Page last updated: 2024-09-05

8-methyladenosine and adenosine

8-methyladenosine has been researched along with adenosine in 6 studies

Compound Research Comparison

Studies
(8-methyladenosine)
Trials
(8-methyladenosine)
Recent Studies (post-2010)
(8-methyladenosine)
Studies
(adenosine)
Trials
(adenosine)
Recent Studies (post-2010) (adenosine)
60132,5361,0758,930

Protein Interaction Comparison

ProteinTaxonomy8-methyladenosine (IC50)adenosine (IC50)
high affinity choline transporter 1 isoform aHomo sapiens (human)0.3851
Sodium/nucleoside cotransporter 1Homo sapiens (human)5.5
Sodium/nucleoside cotransporter 2Homo sapiens (human)5.5
Adenosine receptor A3Homo sapiens (human)0.0011
Adenosine receptor A1Homo sapiens (human)0.0023
Equilibrative nucleoside transporter 1Homo sapiens (human)63
Solute carrier family 28 member 3Homo sapiens (human)3.3

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (33.33)18.2507
2000's2 (33.33)29.6817
2010's2 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hirota, K; Kitade, Y; Maki, Y; Nakata, Y; Pabuccuoglu, A; Torrence, PF1
De Clercq, E; Herdewijn, PA; Ikeda, S; Mamos, P; Van Aerschot, AA; Weyns, NJ1
Giessing, AM; Gondela, A; Hansen, LH; Jensen, SS; Kirpekar, F; Long, K; Rasmussen, A; Vester, B1
Kitade, Y; Kitamura, Y; Kito, S; Nagaoka, K; Ueno, Y1
Kitade, Y; Kitamura, Y; Nagaoka, K; Ueno, Y1
Agris, PF; Cantara, WA; Crain, PF; Fabris, D; Harris, KA; McCloskey, JA; Rozenski, J; Vendeix, FA; Zhang, X1

Other Studies

6 other study(ies) available for 8-methyladenosine and adenosine

ArticleYear
8-Methyladenosine-substituted analogues of 2-5A: synthesis and their biological activities.
    Nucleic acids research, 1991, Aug-11, Volume: 19, Issue:15

    Topics: Adenine Nucleotides; Adenosine; Animals; Endoribonucleases; Kinetics; Liver Extracts; Magnetic Resonance Spectroscopy; Methylation; Oligoribonucleotides; Phosphodiesterase I; Phosphoric Diester Hydrolases; Protein Biosynthesis; Rats; RNA

1991
Antiviral activity of C-alkylated purine nucleosides obtained by cross-coupling with tetraalkyltin reagents.
    Journal of medicinal chemistry, 1993, Oct-01, Volume: 36, Issue:20

    Topics: Adenosine; Antiviral Agents; Cell Line; Herpesvirus 1, Human; HIV-1; HIV-2; Humans; Indicators and Reagents; Organotin Compounds; Respiratory Syncytial Viruses; Vaccinia virus

1993
Identification of 8-methyladenosine as the modification catalyzed by the radical SAM methyltransferase Cfr that confers antibiotic resistance in bacteria.
    RNA (New York, N.Y.), 2009, Volume: 15, Issue:2

    Topics: Adenosine; Anti-Bacterial Agents; Catalysis; Chromatography, High Pressure Liquid; Chromatography, Liquid; Drug Resistance, Bacterial; Escherichia coli; Escherichia coli Proteins; Methylation; Methyltransferases; Nucleic Acid Conformation; RNA, Ribosomal, 23S; Spectrometry, Mass, Electrospray Ionization

2009
Introduction of 8-methyladenosine into 2', 5'-oligoadenylate (2-5A) 2'-terminus induces dramatic shift in binding site of RNase L.
    Nucleic acids symposium series (2004), 2009, Issue:53

    Topics: Adenine Nucleotides; Adenosine; Binding Sites; Endoribonucleases; Humans; Models, Molecular; Oligoribonucleotides

2009
5'-O-dephosphorylated 2',5'-oligoadenylate (2-5A) with 8-methyladenosine at the 2'-terminus activates human RNase L.
    Bioorganic & medicinal chemistry letters, 2010, Feb-01, Volume: 20, Issue:3

    Topics: Adenine Nucleotides; Adenosine; Animals; Crystallography, X-Ray; Endoribonucleases; Enzyme Activation; Humans; Oligoribonucleotides; Phosphorylation; Recombinant Proteins; Snake Venoms

2010
The RNA Modification Database, RNAMDB: 2011 update.
    Nucleic acids research, 2011, Volume: 39, Issue:Database i

    Topics: Adenosine; Cytidine; Databases, Nucleic Acid; RNA; RNA Processing, Post-Transcriptional

2011