8-methoxymethyl-3-isobutyl-1-methylxanthine has been researched along with zaprinast in 2 studies
| Studies (8-methoxymethyl-3-isobutyl-1-methylxanthine) | Trials (8-methoxymethyl-3-isobutyl-1-methylxanthine) | Recent Studies (post-2010) (8-methoxymethyl-3-isobutyl-1-methylxanthine) | Studies (zaprinast) | Trials (zaprinast) | Recent Studies (post-2010) (zaprinast) |
|---|---|---|---|---|---|
| 33 | 0 | 13 | 576 | 2 | 87 |
| Protein | Taxonomy | 8-methoxymethyl-3-isobutyl-1-methylxanthine (IC50) | zaprinast (IC50) |
|---|---|---|---|
| cGMP-specific 3',5'-cyclic phosphodiesterase | Homo sapiens (human) | 1.9442 | |
| cGMP-specific 3',5'-cyclic phosphodiesterase | Canis lupus familiaris (dog) | 0.76 | |
| Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A | Bos taurus (cattle) | 2.6 | |
| Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A | Homo sapiens (human) | 3.55 | |
| Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B | Bos taurus (cattle) | 2.6 | |
| Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B | Homo sapiens (human) | 3.55 | |
| Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C | Homo sapiens (human) | 3.55 | |
| cGMP-specific 3',5'-cyclic phosphodiesterase | Bos taurus (cattle) | 0.4 | |
| G-protein coupled receptor 35 | Homo sapiens (human) | 0.8294 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ahn, HS; Bercovici, A; Boykow, G; Bronnenkant, A; Chackalamannil, S; Chow, J; Cleven, R; Cook, J; Czarniecki, M; Domalski, C; Fawzi, A; Green, M; Gündes, A; Ho, G; Laudicina, M; Lindo, N; Ma, K; Manna, M; McKittrick, B; Mirzai, B; Nechuta, T; Neustadt, B; Puchalski, C; Pula, K; Zhang, H | 1 |
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
2 other study(ies) available for 8-methoxymethyl-3-isobutyl-1-methylxanthine and zaprinast
| Article | Year |
|---|---|
Potent tetracyclic guanine inhibitors of PDE1 and PDE5 cyclic guanosine monophosphate phosphodiesterases with oral antihypertensive activity.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 3',5'-Cyclic-GMP Phosphodiesterases; Administration, Oral; Animals; Antihypertensive Agents; Blood Pressure; Cyclic Nucleotide Phosphodiesterases, Type 1; Cyclic Nucleotide Phosphodiesterases, Type 5; Guanine; Indicators and Reagents; Isoenzymes; Kinetics; Magnetic Resonance Spectroscopy; Molecular Structure; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Pyrroles; Rats; Rats, Inbred SHR; Structure-Activity Relationship | 1997 |
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |