Compounds > 8-hydroxynorcocaine
Page last updated: 2024-09-04

8-hydroxynorcocaine and norcocaine

8-hydroxynorcocaine has been researched along with norcocaine in 7 studies

Compound Research Comparison

Studies
(8-hydroxynorcocaine)		Trials
(8-hydroxynorcocaine)		Recent Studies (post-2010)
(8-hydroxynorcocaine)		Studies
(norcocaine)		Trials
(norcocaine)		Recent Studies (post-2010) (norcocaine)
1200133127

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19903 (42.86)18.7374
1990's3 (42.86)18.2507
2000's1 (14.29)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Alroy, J; Powers, JF; Shuster, L1
Kloss, MW; Rauckman, EJ; Rosen, GM1
Freeman, RW; Harbison, RD; Teaf, CM1
Casey, E; Shuster, L; Welankiwar, SS1
Evans, JE; Greenblatt, DJ; LeDuc, BW; Shuster, L; Sinclair, JF; Sinclair, PR1
Bornheim, LM1
Boelsterli, UA; Boess, F; Ndikum-Moffor, FM; Roberts, SM1

Other Studies

7 other study(ies) available for 8-hydroxynorcocaine and norcocaine

ArticleYear
Hepatic morphologic and biochemical changes induced by subacute cocaine administration in mice.
    Toxicologic pathology, 1992, Volume: 20, Issue:1

    Topics: Alanine Transaminase; Animals; Chemical and Drug Induced Liver Injury; Cocaine; Cytochrome P-450 Enzyme System; Endoplasmic Reticulum; Immunohistochemistry; Liver; Male; Mice; Mice, Inbred A; Mice, Inbred C57BL; Microscopy, Electron; Microsomes, Liver; Mitochondria, Liver; Ribosomes

1992
Biotransformation of norcocaine to norcocaine nitroxide by rat brain microsomes.
    Psychopharmacology, 1984, Volume: 84, Issue:2

    Topics: Animals; Biotransformation; Brain; Cocaine; Cytochrome P-450 Enzyme System; Electron Spin Resonance Spectroscopy; In Vitro Techniques; Kinetics; Male; Microsomes; Rats; Rats, Inbred Strains

1984
Cocaine-induced hepatotoxicity: lipid peroxidation as a possible mechanism.
    Drug and chemical toxicology, 1984, Volume: 7, Issue:4

    Topics: Alanine Transaminase; Animals; Chemical and Drug Induced Liver Injury; Cocaine; Cytochrome P-450 Enzyme System; Lipid Peroxides; Male; Malondialdehyde; Mice; Mixed Function Oxygenases; Oxidation-Reduction; Phenobarbital

1984
Metabolism of cocaine and norcocaine to N-hydroxynorcocaine.
    Biochemical pharmacology, 1983, Oct-15, Volume: 32, Issue:20

    Topics: Animals; Chromatography, High Pressure Liquid; Cocaine; Cytochrome P-450 Enzyme Inhibitors; Male; Mass Spectrometry; Mice; Microsomes

1983
Norcocaine and N-hydroxynorcocaine formation in human liver microsomes: role of cytochrome P-450 3A4.
    Pharmacology, 1993, Volume: 46, Issue:5

    Topics: Cells, Cultured; Chromatography, High Pressure Liquid; Cocaine; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Gas Chromatography-Mass Spectrometry; Humans; Immunoblotting; In Vitro Techniques; Microsomes, Liver; Mixed Function Oxygenases

1993
Effect of cytochrome P450 inducers on cocaine-mediated hepatotoxicity.
    Toxicology and applied pharmacology, 1998, Volume: 150, Issue:1

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carboxylic Ester Hydrolases; Chemical and Drug Induced Liver Injury; Cocaine; Cytochrome P-450 Enzyme System; Dexamethasone; Enzyme Induction; Excitatory Amino Acid Antagonists; Hypnotics and Sedatives; Isoenzymes; Liver; Male; Mice; Narcotics; Phencyclidine; Phenobarbital

1998
Effects of cocaine and its oxidative metabolites on mitochondrial respiration and generation of reactive oxygen species.
    Biochemical pharmacology, 2000, Sep-01, Volume: 60, Issue:5

    Topics: Animals; Cell Respiration; Cocaine; Dopamine Uptake Inhibitors; In Vitro Techniques; Mice; Mice, Inbred ICR; Mitochondria; Reactive Oxygen Species; Rhodamines

2000