8-hydroxyloxapine has been researched along with loxapine in 5 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (20.00) | 18.7374 |
| 1990's | 2 (40.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (40.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cheung, SW; Remington, G; Tang, SW | 1 |
| Burrows, GD; Fulton, A; Norman, T | 1 |
| Hawes, EM; Hsia, D; Hubbard, JW; McKay, G; Midha, KK | 1 |
| Wo, SK; Wong, YC; Zuo, Z | 1 |
| Cassella, JV; Spyker, DA; Yeung, PP | 1 |
2 trial(s) available for 8-hydroxyloxapine and loxapine
| Article | Year |
|---|---|
The role of metabolites in a bioequivalence study 1: loxapine, 7-hydroxyloxapine and 8-hydroxyloxapine.
Topics: Adolescent; Adult; Humans; Loxapine; Male; Middle Aged; Therapeutic Equivalency | 1993 |
A randomized, placebo-controlled repeat-dose thorough QT study of inhaled loxapine in healthy volunteers.
Topics: Action Potentials; Administration, Inhalation; Adult; Antipsychotic Agents; Biotransformation; Cross-Over Studies; Double-Blind Method; Drug Administration Schedule; Female; Healthy Volunteers; Heart Conduction System; Humans; Least-Squares Analysis; Loxapine; Male; Middle Aged; Risk Assessment; Treatment Outcome; Young Adult | 2015 |
3 other study(ies) available for 8-hydroxyloxapine and loxapine
| Article | Year |
|---|---|
Simultaneous quantitation of loxapine, amoxapine and their 7- and 8-hydroxy metabolites in plasma by high-performance liquid chromatography.
Topics: Amoxapine; Animals; Binding, Competitive; Chromatography, High Pressure Liquid; Corpus Striatum; Humans; Hydroxylation; Loxapine; Rats; Spiperone | 1991 |
Ligand binding and platelet uptake studies of loxapine, amoxapine and their 8-hydroxylated derivatives.
Topics: Amoxapine; Animals; Binding, Competitive; Blood Platelets; Brain; Dibenzoxazepines; Imipramine; Loxapine; Rats; Rats, Inbred Lew; Receptors, Dopamine; Receptors, Serotonin; Serotonin; Spiperone | 1982 |
Investigation of the disposition of loxapine, amoxapine and their hydroxylated metabolites in different brain regions, CSF and plasma of rat by LC-MS/MS.
Topics: Administration, Oral; Amoxapine; Animals; Brain; Chromatography, Liquid; Hydroxylation; Loxapine; Male; Methanol; Perchlorates; Rats; Rats, Wistar; Sensitivity and Specificity; Tandem Mass Spectrometry | 2012 |