8-hydroxyguanine has been researched along with 7-deazaguanine* in 1 studies
1 other study(ies) available for 8-hydroxyguanine and 7-deazaguanine
Article | Year |
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Kinetics and thermodynamics of G-quadruplexes.
The melting of tetramolecular DNA or RNA quadruplexes is kinetically irreversible. However, rather than being a hindrance, this kinetic inertia allows us to study association and dissociation processes independently. General rules have been extended to longer DNA motifs or sequences containing modified bases such as 8-oxo or 7-deaza guanine. Results were compared with the canonical TG4T and TG5T tetramers: we demonstrate huge differences (up to 10(5)-fold) in the association constants of these quadruplexes depending on primary sequence. Topics: DNA; G-Quadruplexes; Guanine; Kinetics; Thermodynamics | 2005 |