8-hydroxygeraniol and geniposidic-acid

To investigate the chemical constituents of Cistanche tubulosa.. The chemical constituents were isolated by solvent extraction together with various chromatographic techniques including preparative HPLC. The structures were elucidated on the basis of chemical evidence and spectral data.. Four iridoid glycosides, one lignan glycoside and one monoterpenoid were isolated from the 95% ethanol extract from the stem of C. tubulosa and identified as adoxosidic acid(I), 8-epiloganic acid(II), geniposidic acid (III), mussaenosidic acid(IV), (+)-syringaresinol-O-beta-D-gluco pyranoside(V) and 8-hydroxygeraniol(VI).. Compounds I and VI were isolated from the genus of Cistanche for the first time. Compounds III, IV and V were isolated from this plant for the first time.

Topics: Carboxylic Acids; Cistanche; Drugs, Chinese Herbal; Glucosides; Iridoid Glucosides; Iridoids; Magnoliopsida; Plant Stems; Terpenes