Compounds > 8-hydroxyamoxapine

Page last updated: 2024-08-23

8-hydroxyamoxapine and amoxapine

8-hydroxyamoxapine has been researched along with amoxapine in 11 studies

Research

Studies (11)

Timeframe	Studies, this research(%)	All Research%
pre-1990	8 (72.73)	18.7374
1990's	1 (9.09)	18.2507
2000's	0 (0.00)	29.6817
2010's	2 (18.18)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Calvo, B; Domínguez-Gil, A; García, MJ; Mariño, EL; Pedraz, JL	1
Cooper, TB; Suckow, RF	1
Calvo, MB; Domínguez-Gil, A; García, MJ; Ledesma, A; Pedraz, JL; Prieto Aguirre, F	1
Kobayashi, A; Nakazawa, K; Sugita, S	1
Burrows, GD; Fulton, A; Norman, T	1
Ketchum, C; Robinson, CA; Scott, JW	1
Johnson, SM; Khalil, SK; Nygard, G	1
Hassan, FM; Tasset, JJ	1
Hsia, D; Hubbard, JW; McKay, G; Midha, KK; Rawson, MJ	1
Wo, SK; Wong, YC; Zuo, Z	1
Ahmad, S; Kong, R; Liu, T; Phan, AT; Scott, JE; Williams, AL; Wong, ST; Yeh, LA; Zhao, H; Zhu, X	1

Trials

1 trial(s) available for 8-hydroxyamoxapine and amoxapine

Article	Year
The role of metabolites in a bioequivalence study II: amoxapine, 7-hydroxyamoxapine, and 8-hydroxyamoxapine. International journal of clinical pharmacology and therapeutics, 1999, Volume: 37, Issue:9 Topics: Adolescent; Adrenergic Uptake Inhibitors; Adult; Amoxapine; Animals; Biological Availability; Chromatography, High Pressure Liquid; Cross-Over Studies; Humans; Middle Aged; Time Factors	1999

Other Studies

10 other study(ies) available for 8-hydroxyamoxapine and amoxapine

Article	Year
Pharmacokinetics of amoxapine and its active metabolites. International journal of clinical pharmacology, therapy, and toxicology, 1985, Volume: 23, Issue:4 Topics: Adult; Amoxapine; Chromatography, Gas; Dibenzoxazepines; Female; Half-Life; Humans; Kinetics; Male; Time Factors	1985
Determination of amoxapine and metabolites in plasma by liquid chromatography with electrochemical detection. Journal of chromatography, 1985, Feb-27, Volume: 338, Issue:1 Topics: Amoxapine; Chromatography, Liquid; Dibenzoxazepines; Electrochemistry; Humans	1985
[Relation of blood levels of amoxapine and its active metabolites to its pharmacologic response and toxicity]. Medicina clinica, 1985, Sep-14, Volume: 85, Issue:7 Topics: Adolescent; Adult; Aged; Amoxapine; Depressive Disorder; Dibenzoxazepines; Half-Life; Humans; Kinetics; Middle Aged	1985
Determination of amoxapine and its metabolites in human serum by high-performance liquid chromatography. Neuropharmacology, 1985, Volume: 24, Issue:12 Topics: Amoxapine; Chromatography, High Pressure Liquid; Dibenzoxazepines; Humans	1985
Ligand binding and platelet uptake studies of loxapine, amoxapine and their 8-hydroxylated derivatives. Journal of affective disorders, 1982, Volume: 4, Issue:2 Topics: Amoxapine; Animals; Binding, Competitive; Blood Platelets; Brain; Dibenzoxazepines; Imipramine; Loxapine; Rats; Rats, Inbred Lew; Receptors, Dopamine; Receptors, Serotonin; Serotonin; Spiperone	1982
Analysis of amoxapine, 8-hydroxyamoxapine, and maprotiline by high-pressure liquid chromatography. Therapeutic drug monitoring, 1983, Volume: 5, Issue:3 Topics: Amoxapine; Anthracenes; Chromatography, High Pressure Liquid; Dibenzoxazepines; Half-Life; Humans; Maprotiline	1983
Isocratic liquid chromatographic method for the determination of amoxapine and its metabolites. Journal of pharmaceutical sciences, 1984, Volume: 73, Issue:5 Topics: Amoxapine; Chromatography, Liquid; Dibenzoxazepines; Humans; Solutions; Spectrophotometry, Ultraviolet	1984
Liquid-chromatographic determination of amoxapine and 8-hydroxyamoxapine in human serum. Clinical chemistry, 1982, Volume: 28, Issue:10 Topics: Amoxapine; Chromatography, High Pressure Liquid; Dibenzoxazepines; Humans; Spectrophotometry, Ultraviolet	1982
Investigation of the disposition of loxapine, amoxapine and their hydroxylated metabolites in different brain regions, CSF and plasma of rat by LC-MS/MS. Journal of pharmaceutical and biomedical analysis, 2012, Jan-25, Volume: 58 Topics: Administration, Oral; Amoxapine; Animals; Brain; Chromatography, Liquid; Hydroxylation; Loxapine; Male; Methanol; Perchlorates; Rats; Rats, Wistar; Sensitivity and Specificity; Tandem Mass Spectrometry	2012
Old drug new use--amoxapine and its metabolites as potent bacterial β-glucuronidase inhibitors for alleviating cancer drug toxicity. Clinical cancer research : an official journal of the American Association for Cancer Research, 2014, Jul-01, Volume: 20, Issue:13 Topics: Amoxapine; Animals; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Camptothecin; Cell Line, Tumor; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Activation; Female; Glycoproteins; Irinotecan; Mice; Molecular Conformation; Molecular Docking Simulation; Molecular Dynamics Simulation; Neoplasms; Protective Agents; Protein Binding; Xenograft Model Antitumor Assays	2014