8-hydroxyadenine and hexachloroiridic-acid

8-hydroxyadenine has been researched along with hexachloroiridic-acid* in 1 studies

Other Studies

1 other study(ies) available for 8-hydroxyadenine and hexachloroiridic-acid

Article	Year
Gel electrophoretic detection of 7,8-dihydro-8-oxoguanine and 7, 8-dihydro-8-oxoadenine via oxidation by Ir (IV). Nucleic acids research, 1998, May-01, Volume: 26, Issue:9 Two gel electrophoretic methods are described for detection of 7, 8-dihydro-8-oxoguanine and 7,8-dihydro-8-oxoadenine based on their further oxidation with one-electron oxidants including IrCl62-and IrBr62-. The products of nucleobase oxidation lead to enhanced piperidine-sensitive cleavage and to highly visible stop points in a primer extension assay. 8-oxoG and 8-oxoA lesions may be distinguished by the latter's inability to be oxidized by IrBr62-compared to IrCl62-Comparison is also made to oxidation by MnO4-. Topics: Adenine; DNA Damage; DNA Primers; Electrophoresis, Polyacrylamide Gel; Guanine; Iridium; Oxidation-Reduction	1998

Article

Year

Gel electrophoretic detection of 7,8-dihydro-8-oxoguanine and 7, 8-dihydro-8-oxoadenine via oxidation by Ir (IV).

Nucleic acids research, 1998, May-01, Volume: 26, Issue:9

Two gel electrophoretic methods are described for detection of 7, 8-dihydro-8-oxoguanine and 7,8-dihydro-8-oxoadenine based on their further oxidation with one-electron oxidants including IrCl62-and IrBr62-. The products of nucleobase oxidation lead to enhanced piperidine-sensitive cleavage and to highly visible stop points in a primer extension assay. 8-oxoG and 8-oxoA lesions may be distinguished by the latter's inability to be oxidized by IrBr62-compared to IrCl62-Comparison is also made to oxidation by MnO4-.

Topics: Adenine; DNA Damage; DNA Primers; Electrophoresis, Polyacrylamide Gel; Guanine; Iridium; Oxidation-Reduction

1998