8-hydroxy-2-(di-n-propylamino)tetralin and yohimbine

8-hydroxy-2-(di-n-propylamino)tetralin has been researched along with yohimbine in 50 studies

Research

Studies (50)

TimeframeStudies, this research(%)All Research%
pre-19903 (6.00)18.7374
1990's30 (60.00)18.2507
2000's7 (14.00)29.6817
2010's9 (18.00)24.3611
2020's1 (2.00)2.80

Authors

AuthorsStudies
Bull, D; den Daas, I; Foord, S; Goodson, S; Kilpatrick, G; Lee, M; Rees, S1
Foulon, C; Kung, HF; Kung, MP1
Adham, N; Bard, JA; Branchek, TA; Vaysse, P; Weinshank, RL; Zgombick, J1
Adham, N; Bard, J; Branchek, TA; Durkin, M; Hartig, PR; Kao, HT; Olsen, M; Schecter, LE; Urquhart, D; Weinshank, RL1
Amlaiky, N; Boschert, U; Grailhe, R; Hen, R; Mattei, MG; Matthes, H; Muscatelli, F; Plassat, JL1
Audia, JE; Baez, M; Cohen, ML; Kursar, JD; Lucaites, VL; Nelson, DL; Nissen, JS; Schenck, KW; Wainscott, DB1
Berardi, F; Caccia, C; Fornaretto, MG; Leopoldo, M; McArthur, RA; Perrone, R; Tortorella, V1
Berardi, F; Caccia, C; Colabufo, NA; Fornaretto, MG; Leopoldo, M; McArthur, RA; Perrone, R; Tortorella, V1
Gommeren, W; Haegeman, G; Heylen, L; Lesage, AS; Leysen, JE; Luyten, WH; Schotte, A; Van de Weyer, I; Van Gompel, P; Vanhoenacker, P; Wouters, R1
Audinot, V; Boutin, JA; Cogé, F; Cussac, D; Dekeyne, A; Galizzi, JP; Gobert, A; Lejeune, F; Millan, MJ; Newman-Tancredi, A; Nicolas, JP; Rivet, JM1
Bartoccini, F; Carminati, P; Castorina, M; Di Cesare, MA; Di Serio, S; Gallo, G; Ghirardi, O; Giorgi, F; Giorgi, L; Minetti, P; Piersanti, G; Tarzia, G; Tinti, MO1
Axe, FU; Bembenek, SD; Butler, CR; Coles, F; Dunford, PJ; Edwards, JP; Fourie, AM; Grice, CA; Karlsson, L; Lundeen, K; Riley, JP; Savall, BM; Tays, KL; Wei, J; Williams, KN; Xue, X1
Altenbach, RJ; Brioni, JD; Carr, TL; Chandran, P; Cowart, MD; Esbenshade, TA; Honore, P; Hsieh, GC; Lewis, LG; Liu, H; Manelli, AM; Marsh, KC; Milicic, I; Miller, TR; Strakhova, MI; Vortherms, TA; Wakefield, BD; Wetter, JM; Witte, DG1
Colau, D; Dolusić, E; Frédérick, R; Larrieu, P; Masereel, B; Moineaux, L; Pilotte, L; Pochet, L; Stroobant, V; Van den Eynde, B; Wouters, J1
Anzini, M; Brogi, S; Butini, S; Campiani, G; Cappelli, A; Caselli, G; Castriconi, F; Gemma, S; Giordani, A; Giorgi, G; Giuliani, G; Lanza, M; Letari, O; Makovec, F; Manini, M; Mennuni, L; Valenti, S1
Belyakov, S; Dambrova, M; Kazoka, H; Kuznecovs, J; Lebedev, A; Liepinsh, E; Mishnev, A; Orlova, N; Ponomaryov, Y; Vavers, E; Veinberg, G; Vikainis, S; Vilskersts, R; Vorona, M; Zvejniece, L1
Bienkowski, P; Bucki, A; Jaśkowska, J; Kazek, G; Kowalski, P; Kołaczkowski, M; Marcinkowska, M; Mierzejewski, P; Mitka, K; Pawłowski, M; Siwek, A; Wasik, A; Wesołowska, A1
Benedetti, G; Del Bello, F; Diamanti, E; Giannella, M; Mammoli, V; Marchioro, C; Mattioli, L; Piergentili, A; Pigini, M; Quaglia, W; Titomanlio, F; Varrone, M1
Bienkowski, P; Bucki, A; Jastrzębska-Więsek, M; Kazek, G; Kołaczkowski, M; Marcinkowska, M; Mierzejewski, P; Partyka, A; Pawłowski, M; Siwek, A; Śniecikowska, J; Wasik, A; Wesołowska, A1
Bednarski, M; Gunia-Krzyżak, A; Marona, H; Nitek, W; Pękala, E; Powroźnik, B; Słoczyńska, K; Walczak, M; Waszkielewicz, AM; Żesławska, E1
Filipek, B; Gunia-Krzyżak, A; Marona, H; Nitek, W; Pańczyk, K; Pękala, E; Rapacz, A; Słoczyńska, K; Waszkielewicz, AM; Żelaszczyk, D; Żesławska, E1
Rabin, RA; Winter, JC2
Guyenet, PG; Nosjean, A1
Harris, LT; King, KA; McCall, RB1
Bach, A; Laurie, DJ; Seeburg, PH; Voigt, MM1
Brown, CM; Kilpatrick, AT; MacKinnon, AC; McGrath, JC; Spedding, M2
De Boer, T; De Vos, CJ; Tonnaer, JA; Van Delft, AM1
Davidson, JM; Kwong, LL; Peroutka, SJ; Smith, ER1
Gonzales, DA; Peroutka, SJ; Shapiro, M1
Winter, JC1
Cheng, CH; Costall, B; Ge, J; Naylor, RJ1
Matsuda, H; Matsumoto, K; Osanai, M; Shimada, T; Terasawa, K; Watanabe, H1
Fernández-Guasti, A; Rodríguez-Manzo, G2
Ahrens, O; Flügge, G; Fuchs, E1
Daniel, EE; Kwan, CY; Shimamoto, H; Shimamoto, Y1
Dakshinamurti, K; Lal, KJ1
Arthur, JM; Casañas, SJ; Raymond, JR1
Bobirnac, I; Schoeffter, P1
Bigl, V; Heider, M; Rossner, S; Schliebs, R1
Bonilla-Jaime, H; Retana-Marquez, S; Velazquez-Moctezuma, J1
Bueno, L; Fioramonti, J; Rouzade, ML1
Brustein, E; Rossignol, S1
Lutz, EA; Shannon, HE1
Carvalho-Netto, EF; Nunes-de-Souza, RL1
Centurión, D; Gupta, S; MaassenVanDenBrink, A; Mehotra, S; Sánchez-López, A; Villalón, CM1
Dogas, Z; Pavlinac Dodig, I; Pecotic, R; Stipica Safic, I; Valic, M; Valic, Z1
González-Morales, E; Rodríguez-Manzo, G1

Other Studies

50 other study(ies) available for 8-hydroxy-2-(di-n-propylamino)tetralin and yohimbine

ArticleYear
Cloning and characterisation of the human 5-HT5A serotonin receptor.
    FEBS letters, 1994, Dec-05, Volume: 355, Issue:3

    Topics: Amino Acid Sequence; Animals; Base Sequence; Brain Chemistry; Cloning, Molecular; Genome, Human; GTP-Binding Proteins; Humans; Mice; Molecular Sequence Data; Radioligand Assay; Receptors, Serotonin; Sequence Analysis, DNA; Sequence Homology, Amino Acid; Sequence Homology, Nucleic Acid; Serotonin; Tissue Distribution; Transfection

1994
Synthesis of (R,S)-2'-trans-7-hydroxy-2-[N-n-propyl-N-(3'-iodo-2'- propenyl)-amino]tetralin (trans-7-OH-PIPAT): a new D3 dopamine receptor ligand.
    Journal of medicinal chemistry, 1993, May-14, Volume: 36, Issue:10

    Topics: Binding Sites; Dopamine Agents; Receptors, Dopamine; Receptors, Dopamine D2; Receptors, Dopamine D3; Salicylamides; Stereoisomerism; Tetrahydronaphthalenes

1993
Cloning of a novel human serotonin receptor (5-HT7) positively linked to adenylate cyclase.
    The Journal of biological chemistry, 1993, Nov-05, Volume: 268, Issue:31

    Topics: Adenylyl Cyclases; Base Sequence; Cloning, Molecular; DNA Primers; Humans; Molecular Sequence Data; Receptors, Serotonin; Sequence Alignment; Sequence Homology, Amino Acid; Serotonin Antagonists; Serotonin Receptor Agonists; Signal Transduction

1993
Cloning of another human serotonin receptor (5-HT1F): a fifth 5-HT1 receptor subtype coupled to the inhibition of adenylate cyclase.
    Proceedings of the National Academy of Sciences of the United States of America, 1993, Jan-15, Volume: 90, Issue:2

    Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Amino Acid Sequence; Animals; Base Sequence; Brain Chemistry; Cloning, Molecular; Colforsin; Dose-Response Relationship, Drug; Gene Library; Guinea Pigs; Humans; Indoles; Lymphocytes; Molecular Sequence Data; Receptors, Serotonin; RNA, Messenger; Sequence Homology, Amino Acid; Serotonin; Serotonin Receptor Agonists; Spiperone; Sulfonamides; Sumatriptan; Tissue Distribution

1993
Mouse 5-hydroxytryptamine5A and 5-hydroxytryptamine5B receptors define a new family of serotonin receptors: cloning, functional expression, and chromosomal localization.
    Molecular pharmacology, 1993, Volume: 43, Issue:3

    Topics: Amino Acid Sequence; Animals; Base Sequence; Brain; Cell Line; Chromosome Mapping; Cloning, Molecular; DNA; Gene Expression; Humans; In Situ Hybridization; Mice; Molecular Sequence Data; Receptors, Serotonin; Serotonin Receptor Agonists

1993
Pharmacological characteristics of the newly cloned rat 5-hydroxytryptamine2F receptor.
    Molecular pharmacology, 1993, Volume: 43, Issue:3

    Topics: Animals; Binding Sites; Cell Line; Cloning, Molecular; Gastric Fundus; Inositol 1,4,5-Trisphosphate; Male; Muscle Contraction; Muscle, Smooth; Radioligand Assay; Rats; Rats, Wistar; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Temperature

1993
1-aryl-4-[(1-tetralinyl)alkyl]piperazines: alkylamido and alkylamino derivatives. Synthesis, 5-HT1A receptor affinity, and selectivity. 3.
    Journal of medicinal chemistry, 1996, Aug-02, Volume: 39, Issue:16

    Topics: Animals; Buspirone; Mass Spectrometry; Molecular Structure; Piperazines; Protein Binding; Rats; Receptors, Adrenergic; Receptors, Dopamine; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin; Serotonin Receptor Agonists

1996
Structure-activity relationship studies on the 5-HT(1A) receptor affinity of 1-phenyl-4-[omega-(alpha- or beta-tetralinyl)alkyl]piperazines. 4.
    Journal of medicinal chemistry, 1996, Dec-06, Volume: 39, Issue:25

    Topics: Magnetic Resonance Spectroscopy; Piperazines; Radioligand Assay; Receptors, Serotonin; Structure-Activity Relationship

1996
Alniditan, a new 5-hydroxytryptamine1D agonist and migraine-abortive agent: ligand-binding properties of human 5-hydroxytryptamine1D alpha, human 5-hydroxytryptamine1D beta, and calf 5-hydroxytryptamine1D receptors investigated with [3H]5-hydroxytryptamin
    Molecular pharmacology, 1996, Volume: 50, Issue:6

    Topics: Animals; Benzopyrans; Cattle; Cloning, Molecular; Glioma; HeLa Cells; Humans; Mice; Migraine Disorders; Propylamines; Protein Binding; Pyrimidines; Radioligand Assay; Receptors, Serotonin; Serotonin Receptor Agonists; Signal Transduction; Tritium; Tumor Cells, Cultured; Vasoconstrictor Agents

1996
Agonist and antagonist actions of yohimbine as compared to fluparoxan at alpha(2)-adrenergic receptors (AR)s, serotonin (5-HT)(1A), 5-HT(1B), 5-HT(1D) and dopamine D(2) and D(3) receptors. Significance for the modulation of frontocortical monoaminergic tr
    Synapse (New York, N.Y.), 2000, Volume: 35, Issue:2

    Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Antagonists; Animals; Antidepressive Agents; Body Temperature; Frontal Lobe; Guinea Pigs; Hippocampus; Humans; Mice; Neurons; Piperoxan; Pyrroles; Rats; Receptor, Serotonin, 5-HT1B; Receptor, Serotonin, 5-HT1D; Receptors, Dopamine D2; Receptors, Dopamine D3; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Swine; Synaptic Transmission; Yohimbine

2000
2-n-Butyl-9-methyl-8-[1,2,3]triazol-2-yl-9H-purin-6-ylamine and analogues as A2A adenosine receptor antagonists. Design, synthesis, and pharmacological characterization.
    Journal of medicinal chemistry, 2005, Nov-03, Volume: 48, Issue:22

    Topics: Adenine; Adenosine A2 Receptor Antagonists; Animals; Cell Line; Cricetinae; Cricetulus; Drug Design; Humans; Imidazoles; Male; Models, Molecular; Motor Activity; Purines; Radioligand Assay; Rats; Rats, Inbred F344; Structure-Activity Relationship; Triazoles

2005
Identification of a potent, selective, and orally active leukotriene a4 hydrolase inhibitor with anti-inflammatory activity.
    Journal of medicinal chemistry, 2008, Jul-24, Volume: 51, Issue:14

    Topics: Administration, Oral; Animals; Anti-Inflammatory Agents; Catalysis; Dogs; Drug Evaluation, Preclinical; Enzyme Inhibitors; Epoxide Hydrolases; Humans; Magnetic Resonance Spectroscopy; Mice; Structure-Activity Relationship

2008
cis-4-(Piperazin-1-yl)-5,6,7a,8,9,10,11,11a-octahydrobenzofuro[2,3-h]quinazolin-2-amine (A-987306), a new histamine H4R antagonist that blocks pain responses against carrageenan-induced hyperalgesia.
    Journal of medicinal chemistry, 2008, Nov-27, Volume: 51, Issue:22

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzofurans; Carrageenan; Disease Models, Animal; Drug Design; Drug Evaluation, Preclinical; Humans; Hyperalgesia; Ligands; Mice; Molecular Structure; Pain; Peritonitis; Quinazolines; Rats; Receptors, G-Protein-Coupled; Receptors, Histamine; Receptors, Histamine H4; Stereoisomerism; Structure-Activity Relationship

2008
Tryptophan 2,3-dioxygenase (TDO) inhibitors. 3-(2-(pyridyl)ethenyl)indoles as potential anticancer immunomodulators.
    Journal of medicinal chemistry, 2011, Aug-11, Volume: 54, Issue:15

    Topics: Animals; Antineoplastic Agents; Biological Availability; Cell Line; Drug Design; Enzyme Inhibitors; Humans; Immunologic Factors; Indoles; Kinetics; Mice; Neoplasms; Structure-Activity Relationship; Tryptophan Oxygenase

2011
Synthesis and structure-activity relationship studies in serotonin 5-HT(1A) receptor agonists based on fused pyrrolidone scaffolds.
    European journal of medicinal chemistry, 2013, Volume: 63

    Topics: Animals; Area Under Curve; Humans; Intestinal Absorption; Ligands; Male; Metabolic Clearance Rate; Models, Chemical; Models, Molecular; Molecular Structure; Protein Binding; Protein Structure, Tertiary; Pyrrolidinones; Radioligand Assay; Receptor, Serotonin, 5-HT1A; Receptors, Serotonin, 5-HT3; Serotonin 5-HT1 Receptor Agonists; Structure-Activity Relationship

2013
Synthesis and biological evaluation of 2-(5-methyl-4-phenyl-2-oxopyrrolidin-1-yl)-acetamide stereoisomers as novel positive allosteric modulators of sigma-1 receptor.
    Bioorganic & medicinal chemistry, 2013, May-15, Volume: 21, Issue:10

    Topics: Acetamides; Allosteric Regulation; Animals; Rats; Rats, Wistar; Receptors, sigma; Sigma-1 Receptor; Stereoisomerism; Structure-Activity Relationship

2013
Novel arylsulfonamide derivatives with 5-HT₆/5-HT₇ receptor antagonism targeting behavioral and psychological symptoms of dementia.
    Journal of medicinal chemistry, 2014, Jun-12, Volume: 57, Issue:11

    Topics: Animals; Antidepressive Agents; Antipsychotic Agents; Avoidance Learning; Benzoxazoles; Catalepsy; CHO Cells; Cricetulus; Dementia; Dopamine D2 Receptor Antagonists; HEK293 Cells; Humans; Male; Models, Molecular; Motor Activity; Radioligand Assay; Rats, Wistar; Receptors, Serotonin; Serotonin Antagonists; Structure-Activity Relationship; Sulfonamides

2014
Low Doses of Allyphenyline and Cyclomethyline, Effective against Morphine Dependence, Elicit an Antidepressant-like Effect.
    ACS medicinal chemistry letters, 2012, Jul-12, Volume: 3, Issue:7

    Topics:

2012
Novel 5-HT6 receptor antagonists/D2 receptor partial agonists targeting behavioral and psychological symptoms of dementia.
    European journal of medicinal chemistry, 2015, Mar-06, Volume: 92

    Topics: Animals; Benzamides; Dementia; Dose-Response Relationship, Drug; Drug Partial Agonism; Humans; Indoles; Ligands; Male; Models, Molecular; Molecular Structure; Piperazines; Quinolones; Rats; Rats, Wistar; Receptors, Dopamine D2; Receptors, Serotonin; Structure-Activity Relationship; Swimming

2015
Design, physico-chemical properties and biological evaluation of some new N-[(phenoxy)alkyl]- and N-{2-[2-(phenoxy)ethoxy]ethyl}aminoalkanols as anticonvulsant agents.
    Bioorganic & medicinal chemistry, 2016, Apr-15, Volume: 24, Issue:8

    Topics: Amino Alcohols; Animals; Anticonvulsants; Chemistry, Physical; Dose-Response Relationship, Drug; Drug Design; Epilepsy; Male; Mice; Microsomes, Liver; Molecular Structure; Pilocarpine

2016
Structure-anticonvulsant activity studies in the group of (E)-N-cinnamoyl aminoalkanols derivatives monosubstituted in phenyl ring with 4-Cl, 4-CH
    Bioorganic & medicinal chemistry, 2017, 01-15, Volume: 25, Issue:2

    Topics: Amino Alcohols; Animals; Anticonvulsants; Crystallography, X-Ray; Disease Models, Animal; Dose-Response Relationship, Drug; Electroshock; Mice; Models, Molecular; Molecular Structure; Rats; Seizures; Structure-Activity Relationship

2017
Yohimbine as a serotonergic agent: evidence from receptor binding and drug discrimination.
    The Journal of pharmacology and experimental therapeutics, 1992, Volume: 263, Issue:2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic alpha-Antagonists; Animals; Isoindoles; Male; Piperazines; Pyrimidines; Rats; Rats, Inbred F344; Receptors, Adrenergic, alpha; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Yohimbine

1992
Role of ventrolateral medulla in sympatholytic effect of 8-OHDPAT in rats.
    The American journal of physiology, 1991, Volume: 260, Issue:3 Pt 2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic alpha-Antagonists; Animals; Clonidine; Dioxanes; Idazoxan; Lumbosacral Region; Male; Medulla Oblongata; Neurons; Pressoreceptors; Rats; Rats, Inbred Strains; Reflex; Sympathetic Nervous System; Sympatholytics; Tetrahydronaphthalenes; Yohimbine

1991
Sympatholytic action of yohimbine mediated by 5-HT1A receptors.
    European journal of pharmacology, 1991, Jun-25, Volume: 199, Issue:2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic alpha-Antagonists; Animals; Blood Pressure; Cats; Clonidine; Heart Rate; Injections, Intravenous; Receptors, Serotonin; Spiperone; Sympathetic Nervous System; Tetrahydronaphthalenes; Yohimbine

1991
Molecular cloning and characterization of a rat brain cDNA encoding a 5-hydroxytryptamine1B receptor.
    The EMBO journal, 1991, Volume: 10, Issue:13

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amino Acid Sequence; Animals; Base Sequence; Binding, Competitive; Brain; Cells, Cultured; Cloning, Molecular; DNA; Humans; Methysergide; Molecular Sequence Data; Nucleic Acid Hybridization; Propranolol; Radioligand Assay; Rats; Receptors, Serotonin; RNA, Messenger; Sequence Alignment; Serotonin; Tetrahydronaphthalenes; Transfection; Yohimbine

1991
Heterogeneity of alpha 2-adrenoceptors in rat cortex but not human platelets can be defined by 8-OH-DPAT, RU 24969 and methysergide.
    British journal of pharmacology, 1990, Volume: 99, Issue:3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Binding, Competitive; Blood Platelets; Cerebral Cortex; Guanosine Triphosphate; In Vitro Techniques; Indoles; Kinetics; Male; Methysergide; Naphthalenes; Oxymetazoline; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Species Specificity; Tetrahydronaphthalenes; Yohimbine

1990
Alpha 2-adrenoceptor subtypes and imidazoline-like binding sites in the rat brain.
    British journal of pharmacology, 1990, Volume: 99, Issue:4

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic alpha-Agonists; Animals; Brain Chemistry; Cattle; Cerebral Cortex; Dioxanes; Hippocampus; Humans; Idazoxan; Imidazoles; Imidazoline Receptors; In Vitro Techniques; Indoles; Kinetics; Male; Methysergide; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Drug; Tetrahydronaphthalenes; Yohimbine

1990
Neurochemical studies with the potential antipsychotic compound trans-5-Chloro-2-methyl-2,3,3a,12b-tetrahydro-1H- dibenz[2,3:6,7]oxepino[4,5-c]pyrrolidine maleate.
    Arzneimittel-Forschung, 1990, Volume: 40, Issue:5

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antipsychotic Agents; Apomorphine; Autonomic Nervous System; Benzazepines; Brain Chemistry; Corpus Striatum; Cyclic AMP; Dibenzocycloheptenes; Dibenzoxepins; Heterocyclic Compounds, 4 or More Rings; In Vitro Techniques; Male; Membranes; Mianserin; Prazosin; Quinuclidinyl Benzilate; Rats; Rats, Inbred Strains; Serotonin; Tetrahydronaphthalenes; Yohimbine

1990
Differential interactions of "prosexual" drugs with 5-hydroxytryptamine1A and alpha 2-adrenergic receptors.
    Behavioral neuroscience, 1986, Volume: 100, Issue:5

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic alpha-Antagonists; Animals; Brain; Dioxanes; Ejaculation; Idazoxan; Imidazoles; Indans; Male; Methoxydimethyltryptamines; Rats; Receptors, Adrenergic, alpha; Receptors, Serotonin; Stimulation, Chemical; Tetrahydronaphthalenes; Yohimbine

1986
Modulation of postdecapitation convulsions in rats by alpha-adrenergic and 5-hydroxytryptamine1A agents.
    Experimental neurology, 1987, Volume: 96, Issue:2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic alpha-Agonists; Animals; Buspirone; Death; Dioxanes; Male; Prazosin; Pyrimidines; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Serotonin; Seizures; Serotonin; Tetrahydronaphthalenes; Yohimbine

1987
Generalization of the discriminative stimulus properties of 8-hydroxy-2-(di-n-propylamino)tetralin (8-OH-DPAT) and ipsapirone to yohimbine.
    Pharmacology, biochemistry, and behavior, 1988, Volume: 29, Issue:1

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Anti-Anxiety Agents; Generalization, Stimulus; Male; Naphthalenes; Pyrimidines; Rats; Rats, Inbred F344; Tetrahydronaphthalenes; Yohimbine

1988
The profiles of interaction of yohimbine with anxiolytic and putative anxiolytic agents to modify 5-HT release in the frontal cortex of freely-moving rats.
    British journal of pharmacology, 1993, Volume: 110, Issue:3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Anti-Anxiety Agents; Benzamides; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cerebral Cortex; Clonidine; Dialysis; Diazepam; Drug Interactions; Extracellular Space; Frontal Lobe; Hydroxyindoleacetic Acid; Male; Ondansetron; Rats; Rats, Inbred Strains; Serotonin; Serotonin Antagonists; Yohimbine

1993
The modified light/dark transition test in mice: evaluation of classic and putative anxiolytic and anxiogenic drugs.
    General pharmacology, 1995, Volume: 26, Issue:1

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Anti-Anxiety Agents; Anxiety; Carbolines; Darkness; Light; Male; Methamphetamine; Mice; Motor Activity; Picrotoxin; Yohimbine

1995
Reversal of sexual exhaustion by serotonergic and noradrenergic agents.
    Behavioural brain research, 1994, Jun-30, Volume: 62, Issue:2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic Agents; Animals; Copulation; Dose-Response Relationship, Drug; Ejaculation; Female; Male; Neural Inhibition; Norepinephrine; Rats; Rats, Wistar; Reaction Time; Satiety Response; Serotonin; Serotonin Receptor Agonists; Sexual Behavior, Animal; Yohimbine

1994
Monoamine receptors in the amygdaloid complex of the tree shrew (Tupaia belangeri).
    The Journal of comparative neurology, 1994, May-22, Volume: 343, Issue:4

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amygdala; Animals; Autoradiography; Iodocyanopindolol; Pindolol; Prazosin; Receptors, Biogenic Amine; Tupaiidae; Yohimbine

1994
Rauwolscine induces contraction in the dog mesenteric artery precontracted with KCl and endothelin-1: mediation via 5-hydroxytryptamine1-like receptors.
    The Journal of pharmacology and experimental therapeutics, 1993, Volume: 264, Issue:1

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic alpha-Antagonists; Animals; Dogs; Drug Interactions; Endothelins; Female; In Vitro Techniques; Kinetics; Male; Mesenteric Arteries; Muscle Contraction; Muscle, Smooth, Vascular; Phenylephrine; Potassium Chloride; Rats; Rats, Wistar; Receptors, Adrenergic, alpha; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Yohimbine

1993
Antagonism of the stimulus effects of yohimbine and 8-hydroxydipropylaminotetralin.
    Pharmacology, biochemistry, and behavior, 1993, Volume: 44, Issue:4

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Alprenolol; Animals; Cerebral Cortex; Discrimination, Psychological; Hippocampus; Male; Pindolol; Piperazines; Radioligand Assay; Rats; Rats, Inbred F344; Receptors, Adrenergic, alpha; Serotonin; Serotonin Antagonists; Yohimbine

1993
Hypotensive action of 5-HT receptor agonists in the vitamin B6-deficient hypertensive rat.
    European journal of pharmacology, 1993, Apr-06, Volume: 234, Issue:2-3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antihypertensive Agents; Blood Pressure; Cerebral Cortex; Clonidine; Dose-Response Relationship, Drug; Heart Rate; Hypertension; Male; Neurons; Piperazines; Rats; Rats, Sprague-Dawley; Riboflavin Deficiency; Serotonin; Serotonin Receptor Agonists; Yohimbine

1993
Partial agonist properties of rauwolscine and yohimbine for the inhibition of adenylyl cyclase by recombinant human 5-HT1A receptors.
    Biochemical pharmacology, 1993, Jun-09, Volume: 45, Issue:11

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adenylyl Cyclase Inhibitors; Animals; Binding, Competitive; Cell Membrane; CHO Cells; Cricetinae; Cricetulus; Humans; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Recombinant Proteins; Serotonin Antagonists; Transfection; Yohimbine

1993
Participation of the central noradrenergic system in the reestablishment of copulatory behavior of sexually exhausted rats by yohimbine, naloxone, and 8-OH-DPAT.
    Brain research bulletin, 1995, Volume: 38, Issue:4

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Benzylamines; Central Nervous System; Copulation; Ejaculation; Male; Motivation; Motor Activity; Naloxone; Narcotic Antagonists; Neurotoxins; Norepinephrine; Rats; Rats, Wistar; Satiety Response; Serotonin Receptor Agonists; Sympathetic Nervous System; Sympatholytics; Yohimbine

1995
5-Hydroxytryptamine 5-HT1D receptors mediating inhibition of cyclic AMP accumulation in Madin-Darby canine kidney (MDCK) cells.
    Naunyn-Schmiedeberg's archives of pharmacology, 1995, Volume: 352, Issue:3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Alprostadil; Animals; Cells, Cultured; Cyclic AMP; Dogs; Dose-Response Relationship, Drug; Drug Interactions; Epithelial Cells; Epithelium; Ketanserin; Kidney Cortex; Methiothepin; Oxadiazoles; Pertussis Toxin; Piperazines; Propranolol; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Structure-Activity Relationship; Sumatriptan; Virulence Factors, Bordetella; Yohimbine

1995
Basal forebrain cholinergic immunolesion by 192IgG-saporin: evidence for a presynaptic location of subpopulations of alpha 2- and beta-adrenergic as well as 5-HT2A receptors on cortical cholinergic terminals.
    Neurochemical research, 1997, Volume: 22, Issue:8

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Acetylcholinesterase; Animals; Antibodies, Monoclonal; Autoradiography; Cerebral Cortex; Cholinergic Fibers; Dihydroalprenolol; Immunotoxins; Isotope Labeling; Ketanserin; Male; N-Glycosyl Hydrolases; Prazosin; Presynaptic Terminals; Prosencephalon; Radioligand Assay; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT2A; Receptors, Adrenergic, alpha; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Receptors, Adrenergic, beta; Receptors, Presynaptic; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Ribosome Inactivating Proteins, Type 1; Saporins; Tritium; Yohimbine

1997
Pharmacological features of masculine sexual behavior in an animal model of depression.
    Pharmacology, biochemistry, and behavior, 1998, Volume: 60, Issue:1

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic alpha-Antagonists; Animals; Animals, Newborn; Clomipramine; Depression; Disease Models, Animal; Humans; Male; Muscarinic Agonists; Oxotremorine; Rats; Rats, Wistar; Serotonin Receptor Agonists; Sexual Behavior, Animal; Yohimbine

1998
Decrease in gastric sensitivity to distension by 5-HT1A receptor agonists in rats.
    Digestive diseases and sciences, 1998, Volume: 43, Issue:9

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic alpha-Antagonists; Animals; Male; Pain Threshold; Piperazines; Pyridines; Rats; Rats, Wistar; Serotonin Antagonists; Serotonin Receptor Agonists; Stomach; Yohimbine

1998
Recovery of locomotion after ventral and ventrolateral spinal lesions in the cat. II. Effects of noradrenergic and serotoninergic drugs.
    Journal of neurophysiology, 1999, Volume: 81, Issue:4

    Topics: 5-Hydroxytryptophan; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Cats; Clonidine; Denervation; Electromyography; Free Radical Scavengers; Locomotion; Methoxamine; Norepinephrine; Quipazine; Serotonin; Serotonin Receptor Agonists; Spinal Cord; Sympatholytics; Sympathomimetics; Yohimbine

1999
Yohimbine produces antinociception in the formalin test in rats: involvement of serotonin(1A) receptors.
    Psychopharmacology, 2000, Volume: 149, Issue:1

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic alpha-Antagonists; Animals; Benzofurans; Bridged Bicyclo Compounds, Heterocyclic; Dose-Response Relationship, Drug; Ergolines; Formaldehyde; Male; Nociceptors; Oxadiazoles; Pain; Pain Measurement; Piperazines; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1D; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Antagonists; Serotonin Receptor Agonists; Time Factors; Yohimbine

2000
Use of the elevated T-maze to study anxiety in mice.
    Behavioural brain research, 2004, Jan-05, Volume: 148, Issue:1-2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic alpha-Antagonists; Analysis of Variance; Animals; Anti-Anxiety Agents; Antidepressive Agents; Anxiety; Appetite Depressants; Avoidance Learning; Caffeine; Carbolines; Central Nervous System Stimulants; Conditioning, Classical; Dose-Response Relationship, Drug; Escape Reaction; Imipramine; Inhibition, Psychological; Male; Maze Learning; Mice; Motor Activity; Random Allocation; Reaction Time; Serotonin Agents; Yohimbine

2004
Potential vascular alpha1-adrenoceptor blocking properties of an array of 5-HT receptor ligands in the rat.
    European journal of pharmacology, 2006, Mar-27, Volume: 535, Issue:1-3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Blood Pressure; Buspirone; Clozapine; Decerebrate State; Dose-Response Relationship, Drug; Drug Interactions; Ergotamine; Heart Rate; Ketanserin; Lisuride; Male; Metergoline; Methiothepin; Methysergide; Phenylephrine; Piperazines; Pizotyline; Prazosin; Pyridines; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Serotonin Antagonists; Serotonin Receptor Agonists; Yohimbine

2006
Phrenic long-term depression evoked by intermittent hypercapnia is modulated by serotonergic and adrenergic receptors in raphe nuclei.
    Journal of neurophysiology, 2018, 07-01, Volume: 120, Issue:1

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic alpha-2 Receptor Antagonists; Animals; Hypercapnia; Long-Term Synaptic Depression; Male; Methysergide; Phrenic Nerve; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic; Receptors, Serotonin; Serotonin Antagonists; Yohimbine

2018
Endocannabinoids mediate long-lasting behavioural and physiological changes in male rats induced by the repeated activation of the mesolimbic system by copulation to satiety.
    Behavioural brain research, 2020, 04-06, Volume: 383

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic alpha-2 Receptor Antagonists; Animals; Behavior, Animal; Copulation; Dopamine; Dopamine Antagonists; Dopaminergic Neurons; Endocannabinoids; Male; Mesencephalon; Neuronal Plasticity; Nucleus Accumbens; Rats; Receptor, Cannabinoid, CB1; Receptors, Dopamine; Satiation; Satiety Response; Serotonin 5-HT1 Receptor Agonists; Ventral Tegmental Area; Yohimbine

2020