Compounds > 8-hydroxy-2-(di-n-propylamino)tetralin

8-hydroxy-2-(di-n-propylamino)tetralin and way 100135

8-hydroxy-2-(di-n-propylamino)tetralin has been researched along with way 100135 in 61 studies

Research

Studies (61)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	32 (52.46)	18.2507
2000's	22 (36.07)	29.6817
2010's	7 (11.48)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Brightwell, CI; Cliffe, IA; Fletcher, A; Forster, EA; Mansell, HL; Reilly, Y; Routledge, C; White, AC	1
Chaput, C; Millan, MJ; Newman-Tancredi, A; Verrièle, L	1
Arborelius, L; Grillner, P; Hacksell, U; Hertel, P; Höök, BB; Nomikos, GG; Svensson, TH	1
Fink, H; Marsden, CA; Voigt, JP	1
Geyer, MA; Sipes, TA	1
Cervo, L; Rossi, C; Samanin, R; Tatarczynska, E	1
Emerit, MB; Hamon, M; Riad, M	1
Löscher, W; Richter, A	1
Cadogan, AK; Kendall, DA; Marsden, CA	1
Fletcher, A; Hartley, JE	1
Fletcher, A; Marsden, CA; Mundey, MK	2
Critchley, DJ; Dourish, CT; Foden, ND; Liddle, CW; Middlefell, VC	1
Dourish, CT; Gurling, J; Routledge, C; Wright, IK	1
Haj-Dahmane, S; Hamon, M; Lanfumey, L	1
Escandon, NA; McCall, RB; Zimmermann, DC	1
Bill, DJ; Bill, SJ; Cliffe, IA; Dover, GM; Fletcher, A; Forster, EA; Haskins, JT; Jones, D; Mansell, HL; Reilly, Y	1
Maura, G; Raiteri, M	1
Bickerdike, MJ; Fletcher, A; Marsden, CA	1
Bietti, G; Borsini, F; Ceci, A; Donetti, A	1
Boksa, J; Charakchieva-Minol, S; Chojnacka-Wójcik, E; Klodzińska, A; Mokrosz, JL	1
Albonetti, E; Farabollini, F; González, MI; Siddiqui, A; Wilson, CA	1
Andrade, M; Caldarola-Pastuszka, M; Jackson, A; Uphouse, L	1
Friedman, E; Tilakaratne, N	1
Bertorello, AM; Pinto-do-O, PC; Soares-da-Silva, P	1
Lima, L; Schmeer, C; Urbina, M	1
Dugar, A; Lakoski, JM	1
Kołodziejczyk, K; Maj, J; Rogóz, Z; Skuza, G	1
Bonvento, G; Borredon, J; Lacombe, P; Seylaz, J	1
Fujii, T; Fujimoto, K; Kawashima, K; Nakai, K; Suzuki, T	1
Comoy, E; Lesourd, M; Protais, P	1
Aguerre, S; Chaouloff, F; Mormede, P	1
Dunn, AJ; Swiergiel, AH	1
Baran, L; Filip, M; Przegaliński, E; Siwanowicz, J	1
Heidenreich, BA; Napier, TC	1
Kalia, V; Kotecha, K; Murray, JF; Salicioni, AM; Siddiqui, A; Wilson, CA	1
Bronowska, A; Dahl, SG; Sylte, I	1
Assié, MB; Colpaert, FC; Cosi, C; Koek, W; Patoiseau, JF; Pauwels, PJ; Vacher, B	1
Lima, L; Obregón, F; Schmeer, C; Urbina, M	1
Esteban, S; García-Sevilla, JA; Sastre-Coll, A	1
Borsini, F; Cassano, GB; Giromella, A; Lucacchini, A; Marazziti, D; Mayer, N; Mazzoni, MR; Naccarato, AG; Palego, L	1
Ajubita, M; Hedo, G; Lopez-Garcia, JA	1
Chocyk, A; Czyrak, A; Fijał, K; Gadek-Michalska, A; Maćkowiak, M; Wedzony, K	1
Bonaventure, P; Hedlund, PB; Kelly, L; Lovenberg, T; Mazur, C; Sutcliffe, JG	1
Abu-Amara, M; Aldairy, C; Hagan, JJ; Siddiqui, A; Wilson, C	1
Carreira, I; Lima, L; Mizrahi, C; Stojanovic, A; Urbina, M	1
Höglund, AU; Kommalage, M	1
Egashira, N; Fujiwara, M; Harada, S; Iwasaki, K; Matsushita, M; Mishima, K; Nishimura, R; Okuno, R	1
Gajendiran, M	1
Chen, W; Marvizón, JC; Song, B	1
Shaharyar, S; Siddiqui, A	1
Imaki, J; Ishihara, S; Kawai, Y; Ohno, Y; Sasa, M; Shimizu, S; Sofue, N	2
Bertoglio, LJ; Carobrez, AP; Moraes, CL	1
Bornstein, JC; Foong, JP; Gwynne, RM; Parry, LJ	1
Anavi-Goffer, S; Bolognini, D; Cascio, MG; Fletcher, PJ; Limebeer, CL; Mechoulam, R; Parker, LA; Pertwee, RG; Rock, EM	1
Antle, MC; Boychuk, JA; McCarthy, RW; Nakanishi, ST; Pittman, QJ; Rodych, JT; Scullion, K; Seto, A; Smith, VM; Teskey, GC; Whelan, PJ; Yamakawa, GR	1
Hasser, EM; Kline, DD; Ostrowski, D; Ostrowski, TD	1
Kazmierska, P; Konopacki, J	1
Iha, HA; Kunisawa, N; Matsubara, N; Nomura, Y; Ohno, Y; Onishi, M; Shimizu, S	1
Li, Y; Li, YH; Wang, J; Xiang, K; Xu, X; Zhao, X; Zheng, L	1

Other Studies

61 other study(ies) available for 8-hydroxy-2-(di-n-propylamino)tetralin and way 100135

Article	Year
(S)-N-tert-butyl-3-(4-(2-methoxyphenyl)-piperazin-1-yl)-2-phenylpropanamide [(S)-WAY-100135]: a selective antagonist at presynaptic and postsynaptic 5-HT1A receptors. Journal of medicinal chemistry, 1993, May-14, Volume: 36, Issue:10 Topics: Animals; Binding Sites; Piperazines; Rats; Receptors, Serotonin; Serotonin Antagonists; Stereoisomerism; Synapses	1993
Labelling of recombinant human and native rat serotonin 5-HT1A receptors by a novel, selective radioligand, [3H]-S 15535: definition of its binding profile using agonists, antagonists and inverse agonists. Naunyn-Schmiedeberg's archives of pharmacology, 1998, Volume: 357, Issue:3 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Affinity Labels; Animals; Binding, Competitive; CHO Cells; Cricetinae; Guanine Nucleotides; Hippocampus; Humans; Male; Membranes; Piperazines; Radiopharmaceuticals; Rats; Rats, Wistar; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Receptor Agonists	1998
5-HT1A receptor antagonists increase the activity of serotonergic cells in the dorsal raphe nucleus in rats treated acutely or chronically with citalopram. Naunyn-Schmiedeberg's archives of pharmacology, 1995, Volume: 352, Issue:2 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Action Potentials; Animals; Citalopram; Electrophysiology; Extracellular Space; Male; Neurons; Piperazines; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Antagonists; Synaptic Transmission	1995
Evidence for the involvement of the 5-HT1A receptor in CCK induced satiety in rats. Naunyn-Schmiedeberg's archives of pharmacology, 1995, Volume: 351, Issue:3 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Cholecystokinin; Eating; Male; Piperazines; Rats; Rats, Wistar; Receptors, Serotonin; Satiety Response; Serotonin Antagonists; Serotonin Receptor Agonists	1995
8-OH-DPAT disruption of prepulse inhibition in rats: reversal with (+)WAY 100,135 and localization of site of action. Psychopharmacology, 1995, Volume: 117, Issue:1 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Dose-Response Relationship, Drug; Hippocampus; Male; Microinjections; Piperazines; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Reflex, Startle; Serotonin Antagonists	1995
Role of 5-HT1A receptors in the antinociceptive action of 8-hydroxy-2-(di-n- propylamino)tetralin in the rat. European journal of pharmacology, 1994, Sep-22, Volume: 263, Issue:1-2 Topics: 5,7-Dihydroxytryptamine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic alpha-Antagonists; Analgesics; Animals; Behavior, Animal; Dioxanes; Dose-Response Relationship, Drug; Drug Interactions; Idazoxan; Injections, Intraventricular; Injections, Subcutaneous; Male; Piperazines; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Serotonin Antagonists	1994
Neurotrophic effects of ipsapirone and other 5-HT1A receptor agonists on septal cholinergic neurons in culture. Brain research. Developmental brain research, 1994, Oct-14, Volume: 82, Issue:1-2 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Acetylcholine; Animals; Autoradiography; Brain; Cell Division; Cells, Cultured; Choline O-Acetyltransferase; Dose-Response Relationship, Drug; Female; Fetus; Immunohistochemistry; Nerve Growth Factors; Neurons; Piperazines; Pregnancy; Propanolamines; Pyrimidines; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Thiophenes; Tritium	1994
The novel selective and silent 5-HT1A receptor antagonist (+)-WAY-100135 aggravates dystonic movements in a mutant hamster model. European journal of pharmacology, 1994, Apr-01, Volume: 255, Issue:1-3 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Behavior, Animal; Cricetinae; Dystonia; Female; Male; Mesocricetus; Mutation; Piperazines; Serotonin Antagonists	1994
Serotonin 5-HT1A receptor activation increases cyclic AMP formation in the rat hippocampus in vivo. Journal of neurochemistry, 1994, Volume: 62, Issue:5 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Analysis of Variance; Animals; Colforsin; Cyclic AMP; Hippocampus; Kinetics; Male; Microdialysis; Piperazines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin Antagonists; Time Factors	1994
The effects of WAY-100135 and 8-hydroxy-2-(di-n-propylamino)tetralin on feeding in the rat. European journal of pharmacology, 1994, Feb-11, Volume: 252, Issue:3 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Behavior, Animal; Dose-Response Relationship, Drug; Feeding Behavior; Hyperphagia; Male; Piperazines; Rats; Rats, Sprague-Dawley; Serotonin Antagonists	1994
Effect of the putative 5-HT1A antagonists WAY100135 and SDZ 216-525 on 5-HT neuronal firing in the guinea-pig dorsal raphe nucleus. Neuropharmacology, 1994, Volume: 33, Issue:1 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Dose-Response Relationship, Drug; Guinea Pigs; In Vitro Techniques; Indoles; Male; Neurons; Piperazines; Raphe Nuclei; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Thiazoles	1994
Effects of the selective 5-HT1A receptor antagonist WAY100135 and its enantiomers on 8-OH-DPAT-induced hyperglycaemia in conscious rats. European journal of pharmacology, 1994, Mar-11, Volume: 254, Issue:1-2 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Blood Glucose; Dose-Response Relationship, Drug; Hyperglycemia; Male; Piperazines; Prazosin; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1; Serotonin Antagonists; Serotonin Receptor Agonists; Stereoisomerism	1994
Neurochemical profile of the selective and silent 5-HT1A receptor antagonist WAY100135: an in vivo microdialysis study. European journal of pharmacology, 1993, Aug-03, Volume: 239, Issue:1-3 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Buspirone; Dopamine; Hippocampus; Injections, Subcutaneous; Male; Microdialysis; Norepinephrine; Piperazines; Rats; Rats, Sprague-Dawley; Serotonin; Serotonin Antagonists; Stereoisomerism	1993
Further assessment of the antagonist properties of the novel and selective 5-HT1A receptor ligands (+)-WAY 100 135 and SDZ 216-525. European journal of pharmacology, 1993, Nov-02, Volume: 249, Issue:1 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adenylyl Cyclases; Animals; Chromans; Electrophysiology; Hippocampus; In Vitro Techniques; Indoles; Male; Piperazines; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Serotonin; Serotonin Receptor Agonists; Spiro Compounds; Thiazoles	1993
Characterization of the serotonin1A receptor antagonist activity of WAY-100135 and spiperone. The Journal of pharmacology and experimental therapeutics, 1994, Volume: 268, Issue:1 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Cats; Membrane Potentials; Neurons; Piperazines; Serotonin Antagonists; Spiperone	1994
WAY100135: a novel, selective antagonist at presynaptic and postsynaptic 5-HT1A receptors. European journal of pharmacology, 1993, Jun-24, Volume: 237, Issue:2-3 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Behavior, Animal; Electrophysiology; Female; Guinea Pigs; Hippocampus; Hypothermia; Ileum; Male; Mice; Piperazines; Radioligand Assay; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Stereoisomerism	1993
Serotonin 5-HT1D and 5-HT1A receptors respectively mediate inhibition of glutamate release and inhibition of cyclic GMP production in rat cerebellum in vitro. Journal of neurochemistry, 1996, Volume: 66, Issue:1 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Afferent Pathways; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cerebellum; Cyclic GMP; Glutamic Acid; Male; N-Methylaspartate; Oxadiazoles; Piperazines; Potassium; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1D; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin; Serotonin Agents; Signal Transduction; Sumatriptan; Synapses; Synaptic Transmission	1996
Attenuation of CCK-induced aversion in rats on the elevated x-maze by the selective 5-HT1A receptor antagonists (+) WAY100135 and WAY100635. Neuropharmacology, 1995, Volume: 34, Issue:7 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Anxiety; Behavior, Animal; Cholecystokinin; Disease Models, Animal; Dose-Response Relationship, Drug; Male; Maze Learning; Peptide Fragments; Piperazines; Pyridines; Rats; Rats, Inbred Strains; Serotonin Antagonists; Sincalide; Time Factors	1995
BIMT 17, a 5-HT1A receptor agonist/5-HT2A receptor antagonist, directly activates postsynaptic 5-HT inhibitory responses in the rat cerebral cortex. Naunyn-Schmiedeberg's archives of pharmacology, 1995, Volume: 352, Issue:3 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic beta-Antagonists; Analysis of Variance; Animals; Antidepressive Agents; Benzimidazoles; Binding, Competitive; Buspirone; Cerebral Cortex; Dose-Response Relationship, Drug; In Vitro Techniques; Iontophoresis; Male; Microelectrodes; Neurons; Piperazines; Prazosin; Propanolamines; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Ritanserin; Serotonin Antagonists; Serotonin Receptor Agonists; Thiophenes	1995
Effects of 8-OHDPAT and 5-HT1A antagonists WAY100135 and WAY100635, on guinea-pig behaviour and dorsal raphe 5-HT neurone firing. British journal of pharmacology, 1996, Volume: 117, Issue:4 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Action Potentials; Animals; Behavior, Animal; Carbidopa; Guinea Pigs; Ketanserin; Male; Neurons; Piperazines; Pyridines; Raphe Nuclei; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists	1996
Structure-activity relationship studies of CNS agents. Part 24: New analogs of N-tert.-butyl-3-[4-(2-methoxyphenyl)-1-piperazinyl]-2-phenylpropanamide (WAY-100135). Die Pharmazie, 1996, Volume: 51, Issue:2 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Behavior, Animal; Binding, Competitive; Cerebral Cortex; Hippocampus; In Vitro Techniques; Male; Piperazines; Radioligand Assay; Rats; Rats, Wistar; Receptors, Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Stereoisomerism; Structure-Activity Relationship	1996
Involvement of the 5-HT1A subtype receptor in the neonatal organization of agonistic behaviour in the rat. Pharmacology, biochemistry, and behavior, 1996, Volume: 54, Issue:1 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Agonistic Behavior; Androgens; Animals; Animals, Newborn; Female; Male; Orchiectomy; Piperazines; Posture; Rats; Rats, Wistar; Receptors, Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Social Behavior	1996
5-HT1A receptor antagonists and lordosis behavior. Neuropharmacology, 1996, Volume: 35, Issue:4 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic beta-Antagonists; Animals; Female; Hypothalamus, Middle; Infusions, Parenteral; Ovariectomy; Ovary; Pindolol; Piperazines; Posture; Propranolol; Rats; Rats, Inbred Strains; Serotonin Antagonists; Serotonin Receptor Agonists; Sexual Behavior, Animal	1996
Genomic responses to 5-HT1A or 5-HT2A/2C receptor activation is differentially regulated in four regions of rat brain. European journal of pharmacology, 1996, Jun-27, Volume: 307, Issue:2 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Blotting, Northern; Brain; Cerebellum; Cerebral Cortex; Corpus Striatum; DNA Probes; Gene Expression; Gene Expression Regulation; Genes, fos; Genes, Immediate-Early; Hippocampus; Ketanserin; Male; Piperazines; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; RNA, Messenger; Serotonin Antagonists; Serotonin Receptor Agonists	1996
Antagonistic actions of renal dopamine and 5-hydroxytryptamine: increase in Na+, K(+)-ATPase activity in renal proximal tubules via activation of 5-HT1A receptors. British journal of pharmacology, 1996, Volume: 117, Issue:6 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Dopamine; Dose-Response Relationship, Drug; In Vitro Techniques; Kidney Tubules, Proximal; Male; Piperazines; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Sodium-Potassium-Exchanging ATPase	1996
5HT1A receptor agonist differentially increases cyclic AMP concentration in intact and lesioned goldfish retina. In vitro inhibition of outgrowth by forskolin. Neurochemistry international, 1996, Volume: 29, Issue:5 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adenylyl Cyclases; Animals; Cells, Cultured; Colforsin; Cyclic AMP; Dopamine Antagonists; Goldfish; Nerve Crush; Nerve Regeneration; Optic Nerve; Piperazines; Retina; Serotonin Antagonists; Serotonin Receptor Agonists	1996
Serotonergic function of aging hippocampal CA3 pyramidal neurons: electrophysiological assessment following administration of 5,7-dihydroxytryptamine in the fimbria-fornix and cingulum bundle. Journal of neuroscience research, 1997, Jan-01, Volume: 47, Issue:1 Topics: 5,7-Dihydroxytryptamine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Aging; Anesthetics, Intravenous; Animals; Chloral Hydrate; Electrophysiology; Excitatory Amino Acid Agonists; Female; Gyrus Cinguli; Iontophoresis; N-Methylaspartate; Piperazines; Pyramidal Cells; Rats; Rats, Inbred F344; Serotonin; Serotonin Agents; Serotonin Antagonists; Serotonin Receptor Agonists	1997
Roxindole, a dopamine autoreceptor agonist with a potential antidepressant activity. II. Effects on the 5-hydroxytryptamine system. Pharmacopsychiatry, 1997, Volume: 30, Issue:2 Topics: 5-Hydroxytryptophan; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antidepressive Agents; Behavior, Animal; Body Temperature; Dopamine Agonists; Fenfluramine; Indoles; Male; Mice; Motor Activity; Oxindoles; Piperazines; Pyridines; Rats; Rats, Wistar; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists	1997
Cerebrovascular consequences of altering serotonergic transmission in conscious rat. Brain research, 1997, Sep-05, Volume: 767, Issue:2 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Analysis of Variance; Animals; Carbon Dioxide; Cerebrovascular Circulation; Laser-Doppler Flowmetry; Linear Models; Male; Motor Activity; Piperazines; Rats; Rats, Sprague-Dawley; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Synaptic Transmission	1997
Effect of WAY-100135 on the hippocampal acetylcholine release potentiated by 8-OH-DPAT, a serotonin1A receptor agonist, in normal and p-chlorophenylalanine-treated rats as measured by in vivo microdialysis. Neuroscience research, 1998, Volume: 31, Issue:1 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Acetylcholine; Animals; Enzyme Inhibitors; Fenclonine; Hippocampus; Male; Microdialysis; Motor Activity; Piperazines; Rats; Rats, Wistar; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Tryptophan Hydroxylase	1998
Similar pharmacological properties of 8-OH-DPAT and alnespirone (S 20499) at dopamine receptors: comparison with buspirone. European journal of pharmacology, 1998, Jul-10, Volume: 352, Issue:2-3 Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Anti-Anxiety Agents; Apomorphine; Behavior, Animal; Benzazepines; Buspirone; Corpus Striatum; Dopamine; Dopamine Agonists; Dose-Response Relationship, Drug; Male; Mice; Piperazines; Raclopride; Salicylamides; Serotonin; Serotonin Antagonists; Spiro Compounds; Tritium	1998
GR 127935 and (+)-WAY 100135 do not affect TFMPP-induced inhibition of 5-HT synthesis in the midbrain and hippocampus of Wistar-Kyoto rats. Neuropharmacology, 1998, Volume: 37, Issue:9 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Antagonists; Adrenergic Uptake Inhibitors; Animals; Hippocampus; Idazoxan; Ketanserin; Male; Mesencephalon; Mianserin; Nerve Endings; Oxadiazoles; Piperazines; Rats; Rats, Inbred WKY; Rats, Wistar; Reserpine; Serotonin; Serotonin Agents; Serotonin Antagonists; Serotonin Receptor Agonists; Species Specificity; Tryptophan Hydroxylase	1998
Lack of evidence for a role of serotonin in interleukin-1-induced hypophagia. Pharmacology, biochemistry, and behavior, 2000, Volume: 65, Issue:3 Topics: 5,7-Dihydroxytryptamine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Eating; Interleukin-1; Ketanserin; Lipopolysaccharides; Male; Mice; Oxadiazoles; Piperazines; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Spiro Compounds; Sulfonamides	2000
Activation of serotonin (5-HT)1A receptors inhibits amphetamine sensitization in mice. Life sciences, 2000, Volume: 66, Issue:11 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamine; Animals; Male; Mice; Motor Activity; Piperazines; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Antagonists; Serotonin Receptor Agonists	2000
Effects of serotonergic 5-HT1A and 5-HT1B ligands on ventral pallidal neuronal activity. Neuroreport, 2000, Sep-11, Volume: 11, Issue:13 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Action Potentials; Animals; Dose-Response Relationship, Drug; Globus Pallidus; Male; Neurons; Piperazines; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1B; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Antagonists; Serotonin Receptor Agonists	2000
Serotonin inhibits luteinizing hormone release via 5-HT1A receptors in the zona incerta of ovariectomised, anaesthetised rats primed with steroids. Neuroendocrinology, 2000, Volume: 72, Issue:5 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Anesthesia; Animals; Estradiol; Female; Luteinizing Hormone; Ovariectomy; Piperazines; Progesterone; Rats; Rats, Wistar; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Ritanserin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Subthalamus	2000
Ligand induced conformational states of the 5-HT(1A) receptor. European journal of pharmacology, 2001, Mar-23, Volume: 416, Issue:1-2 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Binding, Competitive; Buspirone; Ligands; Models, Molecular; Molecular Structure; Piperazines; Protein Conformation; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Rhodopsin; Serotonin Antagonists; Serotonin Receptor Agonists; Thermodynamics	2001
5-HT1A receptor activation and antidepressant-like effects: F 13714 has high efficacy and marked antidepressant potential. European journal of pharmacology, 2001, May-25, Volume: 420, Issue:2-3 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aminopyridines; Animals; Antidepressive Agents; Binding, Competitive; Buspirone; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Guanosine 5'-O-(3-Thiotriphosphate); HeLa Cells; Humans; Male; Motor Activity; Piperazines; Piperidines; Pyridines; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Antagonists; Serotonin Receptor Agonists; Swimming	2001
Further characterization of 5-HT1A receptors in the goldfish retina: role of cyclic AMP in the regulation of the in vitro outgrowth of retinal explants. Neurochemical research, 2001, Volume: 26, Issue:3 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adenine; Adenylyl Cyclase Inhibitors; Animals; Cyclic AMP; Enzyme Inhibitors; Goldfish; Imines; In Vitro Techniques; Piperazines; Quinolines; Radioligand Assay; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Retina; Serotonin Antagonists; Serotonin Receptor Agonists; Tritium	2001
Supersensitivity of 5-HT1A autoreceptors and alpha2-adrenoceptors regulating monoamine synthesis in the brain of morphine-dependent rats. Naunyn-Schmiedeberg's archives of pharmacology, 2002, Volume: 365, Issue:3 Topics: 5-Hydroxytryptophan; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Autoreceptors; Biogenic Monoamines; Brain; Dihydroxyphenylalanine; Male; Morphine; Morphine Dependence; Naloxone; Narcotics; Norepinephrine; Piperazines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Receptor Agonists; Substance Withdrawal Syndrome	2002
Region-dependent effects of flibanserin and buspirone on adenylyl cyclase activity in the human brain. The international journal of neuropsychopharmacology, 2002, Volume: 5, Issue:2 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adenylyl Cyclases; Aged; Aged, 80 and over; Benzimidazoles; Binding, Competitive; Brain; Buspirone; Colforsin; Dose-Response Relationship, Drug; Female; Hippocampus; Humans; Male; Middle Aged; Piperazines; Prefrontal Cortex; Raphe Nuclei; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists	2002
Role of serotonin1A receptors on the modulation of rat spinal mono-synaptic reflexes in vitro. Neuroscience letters, 2002, Dec-06, Volume: 334, Issue:1 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Electric Stimulation; Organ Culture Techniques; Piperazines; Rats; Rats, Wistar; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Reflex, Monosynaptic; Serotonin; Serotonin Agents; Serotonin Antagonists; Serotonin Receptor Agonists; Spinal Cord; Spinal Nerve Roots	2002
8-OHDPAT-induced disruption of prepulse inhibition in rats is attenuated by prolonged corticosterone treatment. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2003, Volume: 28, Issue:7 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenal Glands; Animals; Anti-Inflammatory Agents; Autoradiography; Binding Sites; Body Weight; Corticosterone; Dose-Response Relationship, Drug; Drug Interactions; Gene Expression Regulation; Hippocampus; Hydroxyindoleacetic Acid; In Situ Hybridization; Male; Neural Inhibition; Organ Size; Piperazines; Raphe Nuclei; Rats; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Reflex, Startle; RNA, Messenger; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Time Factors	2003
8-OH-DPAT acts on both 5-HT1A and 5-HT7 receptors to induce hypothermia in rodents. European journal of pharmacology, 2004, Mar-08, Volume: 487, Issue:1-3 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Body Temperature; Body Temperature Regulation; Female; Hypothermia; Imidazoles; Indoles; Mice; Phenols; Piperazines; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1A; Receptors, Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Sulfonamides; Telemetry	2004
5-HT7 receptor subtype as a mediator of the serotonergic regulation of luteinizing hormone release in the zona incerta. European journal of pharmacology, 2004, Apr-26, Volume: 491, Issue:1 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Female; Luteinizing Hormone; Male; Ovariectomy; Phenols; Piperazines; Rats; Rats, Wistar; Receptors, Serotonin; Ritanserin; Serotonin; Serotonin 5-HT1 Receptor Antagonists; Serotonin 5-HT2 Receptor Antagonists; Serotonin Antagonists; Serotonin Receptor Agonists; Subthalamus; Sulfonamides	2004
Differential cAMP levels and serotonin effects in blood peripheral mononuclear cells and lymphocytes from major depression patients. International immunopharmacology, 2004, Volume: 4, Issue:8 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adult; Colforsin; Cyclic AMP; Depressive Disorder, Major; Female; Humans; In Vitro Techniques; Leukocytes, Mononuclear; Lymphocytes; Male; Middle Aged; Norepinephrine; Piperazines; Serotonin; Serotonin 5-HT1 Receptor Agonists; Serotonin 5-HT1 Receptor Antagonists; Serotonin Antagonists	2004
Involvement of spinal serotonin receptors in the regulation of intraspinal acetylcholine release. European journal of pharmacology, 2005, Feb-21, Volume: 509, Issue:2-3 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Acetylcholine; Amphetamines; Animals; Biguanides; Citalopram; Dose-Response Relationship, Drug; Ketanserin; Male; Microdialysis; Piperazines; Pyridines; Pyrroles; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Spinal Cord; Time Factors	2005
Perospirone, a novel antipsychotic drug, inhibits marble-burying behavior via 5-HT1A receptor in mice: implications for obsessive-compulsive disorder. Journal of pharmacological sciences, 2005, Volume: 99, Issue:2 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antipsychotic Agents; Behavior, Animal; Disease Models, Animal; Dose-Response Relationship, Drug; Haloperidol; Indoles; Isoindoles; Male; Mice; Mice, Inbred ICR; Motor Activity; Obsessive-Compulsive Disorder; Piperazines; Receptor, Serotonin, 5-HT1A; Risperidone; Serotonin Antagonists; Serotonin Receptor Agonists; Thiazoles	2005
Neuromodulatory role of 5-hydroxytryptamine type 1A receptors on the excitability of Renshaw cells in the rat spinal cord. Neuroreport, 2006, Aug-21, Volume: 17, Issue:12 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Action Potentials; Animals; Drug Interactions; Interneurons; Lumbosacral Region; Male; Piperazines; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1A; Serotonin Antagonists; Serotonin Receptor Agonists; Spinal Cord	2006
Inhibition of opioid release in the rat spinal cord by serotonin 5-HT(1A) receptors. Brain research, 2007, Jul-16, Volume: 1158 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Analgesics, Opioid; Analysis of Variance; Animals; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; In Vitro Techniques; Male; Neural Inhibition; Oligopeptides; Piperazines; Protein Transport; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1A; Receptors, Opioid, mu; Serotonin Antagonists; Serotonin Receptor Agonists; Spinal Cord	2007
Attenuating effects of prior oestradiol benzoate priming on 5-HT-mediated lordosis behavior in rats are dose-dependent. Acta physiologica Hungarica, 2007, Volume: 94, Issue:3 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Brain; Dopamine Antagonists; Dose-Response Relationship, Drug; Estradiol; Female; Male; Ovariectomy; Phenols; Piperazines; Posture; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT1A; Receptors, Serotonin; Reflex; Serotonin; Serotonin Receptor Agonists; Sexual Behavior, Animal; Sulfonamides	2007
Evaluation of the antibradykinetic actions of 5-HT1A agonists using the mouse pole test. Progress in neuro-psychopharmacology & biological psychiatry, 2008, Jul-01, Volume: 32, Issue:5 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antipsychotic Agents; Behavior, Animal; Disease Models, Animal; Dose-Response Relationship, Drug; Fenclonine; Haloperidol; Hypokinesia; Isoindoles; Male; Mice; Motor Activity; Muscarinic Antagonists; Piperazines; Pyrimidines; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Trihexyphenidyl	2008
Anticataleptic 8-OH-DPAT preferentially counteracts with haloperidol-induced Fos expression in the dorsolateral striatum and the core region of the nucleus accumbens. Neuropharmacology, 2008, Volume: 55, Issue:5 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Behavior, Animal; Catalepsy; Corpus Striatum; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Fenclonine; Gene Expression Regulation; Haloperidol; Male; Mice; Nucleus Accumbens; Oncogene Proteins v-fos; Piperazines; Serotonin Antagonists; Serotonin Receptor Agonists; Statistics, Nonparametric	2008
Interplay between glutamate and serotonin within the dorsal periaqueductal gray modulates anxiety-related behavior of rats exposed to the elevated plus-maze. Behavioural brain research, 2008, Dec-12, Volume: 194, Issue:2 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Analysis of Variance; Animals; Anxiety; Behavior, Animal; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Agonists; Glutamic Acid; Male; Maze Learning; N-Methylaspartate; Periaqueductal Gray; Piperazines; Rats; Rats, Wistar; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists	2008
5-HT(1A), SST(1), and SST(2) receptors mediate inhibitory postsynaptic potentials in the submucous plexus of the guinea pig ileum. American journal of physiology. Gastrointestinal and liver physiology, 2010, Volume: 298, Issue:3 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Electric Stimulation; Excitatory Postsynaptic Potentials; Female; Gene Expression; Guinea Pigs; Idazoxan; Ileum; Inhibitory Postsynaptic Potentials; Lysine; Male; Myenteric Plexus; Neurons; Norepinephrine; Oligopeptides; Piperazines; Quinolines; Receptor, Serotonin, 5-HT1A; Receptors, Somatostatin; Serotonin; Serotonin 5-HT1 Receptor Agonists; Serotonin 5-HT1 Receptor Antagonists; Serotonin Receptor Agonists; Somatostatin; Submucous Plexus; Vasoactive Intestinal Peptide	2010
Cannabidiol, a non-psychotropic component of cannabis, attenuates vomiting and nausea-like behaviour via indirect agonism of 5-HT(1A) somatodendritic autoreceptors in the dorsal raphe nucleus. British journal of pharmacology, 2012, Volume: 165, Issue:8 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antiemetics; Behavior, Animal; Cannabidiol; Cannabis; Female; Male; Nausea; Piperazines; Pyridines; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1A; Serotonin 5-HT1 Receptor Agonists; Serotonin 5-HT1 Receptor Antagonists; Shrews; Vomiting	2012
Serotonin 1A receptors alter expression of movement representations. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2013, Mar-13, Volume: 33, Issue:11 Topics: 5,7-Dihydroxytryptamine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Action Potentials; Analysis of Variance; Animals; Brain Mapping; Chromatography, High Pressure Liquid; Forelimb; H-Reflex; Male; Mice; Mice, Knockout; Microinjections; Motor Cortex; Movement; Neurons; Patch-Clamp Techniques; Piperazines; Psychomotor Performance; Raphe Nuclei; Rats; Rats, Long-Evans; Receptor, Serotonin, 5-HT1A; Serotonin; Serotonin Agents; Spinal Cord; Tryptophan Hydroxylase	2013
Depressed GABA and glutamate synaptic signaling by 5-HT1A receptors in the nucleus tractus solitarii and their role in cardiorespiratory function. Journal of neurophysiology, 2014, Jun-15, Volume: 111, Issue:12 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Excitatory Postsynaptic Potentials; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Male; Phrenic Nerve; Piperazines; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1A; Receptors, GABA-A; Respiration; Serotonin 5-HT1 Receptor Agonists; Serotonin 5-HT1 Receptor Antagonists; Solitary Nucleus; Synaptic Transmission; Tissue Culture Techniques	2014
Development of theta rhythm in hippocampal formation slices perfused with 5-HT1A antagonist, (S)WAY 100135. Brain research, 2015, Nov-02, Volume: 1625 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Analysis of Variance; Animals; Carbachol; Cholinergic Agonists; Dose-Response Relationship, Drug; Electroencephalography; Hippocampus; In Vitro Techniques; Male; Piperazines; Rats; Rats, Wistar; Serotonin Antagonists; Serotonin Receptor Agonists; Theta Rhythm; Time Factors	2015
Serotonergic modulation of nicotine-induced kinetic tremor in mice. Journal of pharmacological sciences, 2017, Volume: 134, Issue:2 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Fenclonine; Humans; Male; Mice; Nicotine; Ondansetron; Piperazines; Receptor, Serotonin, 5-HT1A; Receptors, Serotonin; Ritanserin; Serotonin Antagonists; Serotonin Receptor Agonists; Tremor	2017
Co-activation of both 5-HT Neuroscience letters, 2018, 11-01, Volume: 686 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Animals, Newborn; Excitatory Postsynaptic Potentials; Piperazines; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1A; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Synaptic Transmission; Visual Cortex	2018