8-hydroxy-2-(di-n-propylamino)tetralin and urapidil

8-hydroxy-2-(di-n-propylamino)tetralin has been researched along with urapidil in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19906 (50.00)18.7374
1990's6 (50.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Fischer, G; Grohs, JG; Huber, S; Raberger, G1
Kotai, E; Singer, EA; Valenta, B; Weisz, E1
Gross, G; Hanft, G; Schüttler, K; Xin, X1
Beller, KD; Kolassa, N; Sanders, KH2
Beller, KD; Boer, R; Sanders, KH; Walter, B1
Boddeke, HW; Doods, HN; Hoyer, D; Kalkman, HO; Mathy, MJ; van Zwieten, PA1
Friedman, E; Gillis, RA; Hamosh, P; Kellar, KJ; Mandal, AK; Pineo, SV1
Ramage, AG; Wilkinson, SJ1
Dretchen, K; Gatti, PJ; Gillis, RA; Hill, K; Kellar, KJ; Martino-Barrows, A; Namath, IJ; Quest, JA1
Beller, KD; Bischler, P; Kolassa, N; Sanders, KH1
Dakshinamurti, K; Lal, KJ1

Reviews

1 review(s) available for 8-hydroxy-2-(di-n-propylamino)tetralin and urapidil

ArticleYear
Involvement of brain 5-HT1A receptors in the hypotensive response to urapidil.
    The American journal of cardiology, 1989, Aug-15, Volume: 64, Issue:7

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic alpha-Antagonists; Animals; Antihypertensive Agents; Blood Pressure; Brain Stem; Cats; Dioxanes; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Female; Heart Rate; Infusions, Intravenous; Male; Piperazines; Receptors, Serotonin; Spiro Compounds; Tetrahydronaphthalenes

1989

Other Studies

11 other study(ies) available for 8-hydroxy-2-(di-n-propylamino)tetralin and urapidil

ArticleYear
Alpha 1-adrenoceptor blockade and/or 5-HT1A agonism during treadmill exercise in dogs.
    Journal of autonomic pharmacology, 1991, Volume: 11, Issue:2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic alpha-Antagonists; Animals; Blood Pressure; Dogs; Heart Rate; Hemodynamics; Physical Exertion; Piperazines; Receptors, Serotonin; Sympathetic Nervous System; Tetrahydronaphthalenes; Vagus Nerve

1991
Influence of urapidil and 8-OH-DPAT on brain 5-HT turnover and blood pressure in rats.
    Journal of cardiovascular pharmacology, 1990, Volume: 15 Suppl 7

    Topics: 5,7-Dihydroxytryptamine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Blood Pressure; Brain Chemistry; Clonidine; Heart Rate; Male; Piperazines; Rats; Rats, Inbred Strains; Serotonin; Serotonin Antagonists; Spinal Cord; Stereotaxic Techniques; Tetrahydronaphthalenes

1990
Urapidil analogues are potent ligands of the 5-HT1A receptor.
    Journal of cardiovascular pharmacology, 1990, Volume: 15 Suppl 7

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Cerebral Cortex; Guanosine Triphosphate; In Vitro Techniques; Ligands; Male; Piperazines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Serotonin; Serotonin Antagonists; Tetrahydronaphthalenes

1990
Involvement of 5-HT1A receptors in blood pressure reduction by 8-OH-DPAT and urapidil in cats.
    Journal of cardiovascular pharmacology, 1990, Volume: 15 Suppl 7

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic beta-Agonists; Animals; Antihypertensive Agents; Blood Pressure; Cats; Dose-Response Relationship, Drug; Female; Heart Rate; Imidazoles; Male; Pindolol; Piperazines; Receptors, Serotonin; Serotonin Antagonists; Tetrahydronaphthalenes

1990
Is blockade of alpha 1-adrenoceptors favourable in hypotension induced by stimulation of serotonin1A receptors in conscious dogs?
    Drugs, 1990, Volume: 40 Suppl 4

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic alpha-Antagonists; Animals; Antihypertensive Agents; Blood Pressure; Dogs; Dose-Response Relationship, Drug; Heart Rate; Male; Piperazines; Prazosin; Rats; Receptors, Serotonin; Stimulation, Chemical; Swine; Tetrahydronaphthalenes

1990
Central 5-HT1A receptors and the mechanism of the central hypotensive effect of (+)8-OH-DPAT, DP-5-CT, R28935, and urapidil.
    Journal of cardiovascular pharmacology, 1988, Volume: 11, Issue:4

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antihypertensive Agents; Benzimidazoles; Blood Pressure; Brain; Cats; Dioxanes; Dioxins; Female; Male; Naphthalenes; Piperazines; Radioligand Assay; Receptors, Serotonin; Swine; Tetrahydronaphthalenes; Tryptamines

1988
Importance of central nervous system serotonin-1A receptors for mediating the hypotensive effect of urapidil.
    The Journal of pharmacology and experimental therapeutics, 1989, Volume: 251, Issue:2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antihypertensive Agents; Blood Pressure; Cats; Heart Rate; Medulla Oblongata; Piperazines; Prazosin; Receptors, Serotonin; Respiration; Spiperone; Tetrahydronaphthalenes

1989
Evidence that different regional sympathetic outflows vary in their sensitivity to the sympathoinhibitory actions of putative 5-HT1A and alpha 2-adrenoceptor agonists in anaesthetized cats.
    British journal of pharmacology, 1989, Volume: 98, Issue:4

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic alpha-Agonists; Anesthesia; Animals; Cats; Clonidine; Hemodynamics; Imidazoles; Male; Piperazines; Receptors, Serotonin; Sympathetic Nervous System; Tetrahydronaphthalenes

1989
Experimental studies on the neurocardiovascular effects of urapidil.
    Drugs, 1988, Volume: 35 Suppl 6

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic alpha-Antagonists; Animals; Antihypertensive Agents; Cats; Drug Interactions; Female; Hemodynamics; Injections, Intraventricular; Male; Microinjections; Nervous System; Piperazines; Receptors, Drug; Serotonin; Sympathetic Nervous System; Tetrahydronaphthalenes

1988
Interaction of urapidil with brain serotonin-1A receptors increases the blood pressure reduction due to peripheral alpha-adrenoceptor inhibition.
    Journal of hypertension. Supplement : official journal of the International Society of Hypertension, 1988, Volume: 6, Issue:2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic alpha-Antagonists; Animals; Antihypertensive Agents; Blood Pressure; Cats; Dioxanes; Female; Male; Piperazines; Receptors, Serotonin; Serotonin Antagonists; Spiro Compounds; Tetrahydronaphthalenes

1988
Hypotensive action of 5-HT receptor agonists in the vitamin B6-deficient hypertensive rat.
    European journal of pharmacology, 1993, Apr-06, Volume: 234, Issue:2-3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antihypertensive Agents; Blood Pressure; Cerebral Cortex; Clonidine; Dose-Response Relationship, Drug; Heart Rate; Hypertension; Male; Neurons; Piperazines; Rats; Rats, Sprague-Dawley; Riboflavin Deficiency; Serotonin; Serotonin Receptor Agonists; Yohimbine

1993