Compounds > 8-hydroxy-2-(di-n-propylamino)tetralin

8-hydroxy-2-(di-n-propylamino)tetralin and uh 301

8-hydroxy-2-(di-n-propylamino)tetralin has been researched along with uh 301 in 35 studies

Research

Studies (35)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	30 (85.71)	18.2507
2000's	5 (14.29)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Andén, NE; Björk, L; Hacksell, U; Hillver, SE; Li, YL; Ross, S; Svensson, B	1
Audinot, V; Chaput, C; Conte, C; Gavaudan, S; Millan, MJ; Newman-Tancredi, A; Touzard, M; Verrièle, L	1
Björk, L; Fredriksson, A; Hacksell, U; Lewander, T	1
Arborelius, L; Nomikos, GG; Svensson, TH	1
Griebel, G; Haefely, WE; Jenck, F; Martin, JR; Moreau, JL; Widmer, U	1
Andén, NE; Björk, L; Cornfield, LJ; Hacksell, U; Hillver, SE; Lewander, T; Nelson, DL	1
Björk, L; Hacksell, U; Lewander, T; Lindgren, S	1
Hacksell, U; Johansson, CE; Meyerson, BJ	1
Arborelius, L; Grillner, P; Hacksell, U; Hertel, P; Höök, BB; Nomikos, GG; Svensson, TH	1
Groenink, L; Maes, RA; Mos, J; Olivier, B; Van der Gugten, J	2
Arborelius, L; Hacksell, U; Höök, BB; Svensson, TH	1
Bengtsson, A; Cortizo, L; Jackson, DM; Johansson, C; Ross, SB	1
Ahlenius, S; Cortizo, L; Wadenberg, ML	1
Berg, M; Johansson-Wallsten, CE; Meyerson, BJ	1
Hjorth, S	1
Hacksell, U; Lewander, T; Liu, Y; Yu, H	1
Arborelius, L; Chergui, K; Chouvet, G; Hacksell, U; Höök, BB; Murase, S; Nomikos, GG; Svensson, TH	1
Gommans, J; Hijzen, TH; Maes, RA; Mos, J; Olivier, B	1
Arborelius, L; Grillner, P; Hacksell, U; Hertel, P; Höök, BB; Nomikos, GG; Salmi, P; Svensson, TH	1
Arborelius, L; Hacksell, U; Höök, BB; Nomikos, GG; Svensson, TH	1
Hacksell, U; Lewander, T; Liu, Y; Malmberg, A; Mohell, N; Yu, H	1
Cortizo, L; Hacksell, U; Höök, BB; Johansson, AM; Mohell, N; Westlind-Danielsson, A	1
Darmani, NA; Reeves, SL	1
Dahl, SG; Edvardsen, O; Sylte, I	1
Björk, L; Cortizo, L; Csöregh, I; Ertan, A; Hacksell, U; Hillver, SE; Höök, BB; Johansson, AM; Johansson, L; Lewander, T; Nordvall, G	1
Bussières, N; El Manira, A; Svensson, E; Zhang, W	1
Darmani, NA; Zhao, W	1
Hong, E; Meneses, A; Terrón, JA	1
Ahlenius, S; Henriksson, I; Magnusson, O; Salmi, P	1
Björk, E; Dahlin, M	1
Ahlenius, S; Kaur, P	1
Lewander, T; Yan, H; Yu, H	1
Koprowska, M; Krotewicz, M; Romaniuk, A; Strzelczuk, M; Wieczorek, M	1
Luthman, J; O'Neill, HC; Rose, GM; Stevens, KE	1

Other Studies

35 other study(ies) available for 8-hydroxy-2-(di-n-propylamino)tetralin and uh 301

Article	Year
(S)-5-fluoro-8-hydroxy-2-(dipropylamino)tetralin: a putative 5-HT1A-receptor antagonist. Journal of medicinal chemistry, 1990, Volume: 33, Issue:6 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Brain; Chemical Phenomena; Chemistry; Dihydroxyphenylalanine; Naphthalenes; Rats; Receptors, Dopamine; Receptors, Dopamine D2; Serotonin; Serotonin Antagonists; Stereoisomerism; Tetrahydronaphthalenes	1990
Agonist and antagonist actions of antipsychotic agents at 5-HT1A receptors: a [35S]GTPgammaS binding study. European journal of pharmacology, 1998, Aug-21, Volume: 355, Issue:2-3 Topics: Animals; Antipsychotic Agents; CHO Cells; Cricetinae; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Agents; Sulfur Radioisotopes	1998
Effects of (R)-8-OH-DPAT and the enantiomers of UH-301 on motor activities in the rat: antagonism of (R)-8-OH-DPAT-induced effects. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 1992, Volume: 2, Issue:2 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Exploratory Behavior; Male; Motor Activity; Rats; Rats, Inbred Strains; Serotonin Antagonists; Stereoisomerism; Tetrahydronaphthalenes	1992
The novel 5-HT1A receptor antagonist (S)-UH-301 prevents (R)-8-OH-DPAT-induced decrease in interstitial concentrations of serotonin in the rat hippocampus. European journal of pharmacology, 1992, Jun-17, Volume: 216, Issue:3 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Analysis of Variance; Animals; Dialysis; Hippocampus; Male; Rats; Rats, Wistar; Serotonin; Serotonin Antagonists; Stereoisomerism	1992
Behavioral profile of the 5HT1A receptor antagonist (S)-UH-301 in rodents and monkeys. Brain research bulletin, 1992, Volume: 29, Issue:6 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Acoustic Stimulation; Animals; Brain; Cerebral Ventricles; Conditioning, Operant; Conflict, Psychological; Ergolines; Exploratory Behavior; Feeding Behavior; Injections, Intraventricular; Ketanserin; Learning; Mice; Mice, Inbred DBA; Motor Activity; N-Methylaspartate; Rats; Receptors, Serotonin; Seizures; Serotonin; Serotonin Antagonists	1992
Pharmacology of the novel 5-hydroxytryptamine1A receptor antagonist (S)-5-fluoro-8-hydroxy-2-(dipropylamino)tetralin: inhibition of (R)-8-hydroxy-2-(dipropylamino)tetralin-induced effects. The Journal of pharmacology and experimental therapeutics, 1991, Jul-01, Volume: 258, Issue:1 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Behavior, Animal; Brain; Dihydroxyphenylalanine; Dose-Response Relationship, Drug; Male; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin; Tetrahydronaphthalenes	1991
(S)-UH-301 antagonizes (R)-8-OH-DPAT-induced cardiovascular effects in the rat. European journal of pharmacology, 1991, Jul-09, Volume: 199, Issue:3 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Cardiovascular System; Consciousness; Male; Rats; Rats, Inbred Strains; Serotonin Antagonists; Sodium Chloride; Stereoisomerism; Tetrahydronaphthalenes	1991
The novel 5-HT1A receptor antagonist (S)-UH-301 antagonizes 8-OH-DPAT-induced effects on male as well as female rat copulatory behaviour. European journal of pharmacology, 1991, Sep-04, Volume: 202, Issue:1 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Copulation; Ejaculation; Female; Male; Rats; Rats, Inbred Strains; Serotonin Antagonists; Sexual Behavior, Animal; Tetrahydronaphthalenes	1991
5-HT1A receptor antagonists increase the activity of serotonergic cells in the dorsal raphe nucleus in rats treated acutely or chronically with citalopram. Naunyn-Schmiedeberg's archives of pharmacology, 1995, Volume: 352, Issue:2 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Action Potentials; Animals; Citalopram; Electrophysiology; Extracellular Space; Male; Neurons; Piperazines; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Antagonists; Synaptic Transmission	1995
The corticosterone-enhancing effects of the 5-HT1A receptor antagonist, (S)-UH301, are not mediated by the 5-HT1A receptor. European journal of pharmacology, 1995, Jan-16, Volume: 272, Issue:2-3 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Behavior, Animal; Blood Glucose; Corticosterone; Male; Piperazines; Rats; Rats, Wistar; Receptors, Serotonin; Serotonin Antagonists	1995
The 5-HT1A receptor antagonist (S)-UH-301 blocks the qR)-8-OH-DPAT-induced inhibition of serotonergic dorsal raphe cell firing in the rat. Journal of neural transmission. General section, 1994, Volume: 96, Issue:3 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Action Potentials; Animals; Dose-Response Relationship, Drug; Electrophysiology; Male; Neurons; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Serotonin; Serotonin Antagonists	1994
Development of tolerance to 8-OH-DPAT induced blockade of acquisition of a passive avoidance response. Neuropharmacology, 1994, Volume: 33, Issue:8 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Avoidance Learning; Depression, Chemical; Dizocilpine Maleate; Drug Tolerance; Male; Memory; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Receptors, Serotonin; Serotonin Antagonists; Stereoisomerism	1994
(S)-UH301, a silent 5-HT1A receptor antagonist, enhances plasma corticosterone levels in the rat. Life sciences, 1994, Volume: 55, Issue:5 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Blood Glucose; Corticosterone; Dose-Response Relationship, Drug; Male; Rats; Rats, Wistar; Serotonin Antagonists	1994
Evidence for specific interactions between 5-HT1A and dopamine D2 receptor mechanisms in the mediation of extrapyramidal motor functions in the rat. Pharmacology, biochemistry, and behavior, 1994, Volume: 47, Issue:3 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Betaxolol; Catalepsy; Dopamine D2 Receptor Antagonists; Extrapyramidal Tracts; Male; Pindolol; Raclopride; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; Receptors, Serotonin; Salicylamides; Serotonin Antagonists	1994
The effects of long-term treatment with the 5-HT1A receptor agonist 8-OH-DPAT and the 5-HT2/1C receptor agonist DOI in the neonatal rat. European journal of pharmacology, 1993, Oct-19, Volume: 243, Issue:2 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Animals, Newborn; Dose-Response Relationship, Drug; Female; Ketanserin; Pregnancy; Rats; Rats, Sprague-Dawley; Serotonin Antagonists; Serotonin Receptor Agonists; Vocalization, Animal	1993
Serotonin 5-HT1A autoreceptor blockade potentiates the ability of the 5-HT reuptake inhibitor citalopram to increase nerve terminal output of 5-HT in vivo: a microdialysis study. Journal of neurochemistry, 1993, Volume: 60, Issue:2 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Chromatography, High Pressure Liquid; Citalopram; Dialysis; Feedback; Hippocampus; Male; Microchemistry; Nerve Endings; Penbutolol; Rats; Rats, Sprague-Dawley; Serotonin; Serotonin Antagonists	1993
(R)- and (S)-8-acetyl-2-(dipropylamino)tetralin (LY-41): two novel 5-HT1A receptor agonists. European journal of pharmacology, 1993, Jan-26, Volume: 231, Issue:1 Topics: 5-Hydroxytryptophan; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Behavior, Animal; Body Temperature; Dihydroxyphenylalanine; Dopamine; Male; Molecular Structure; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Stereoisomerism; Tetrahydronaphthalenes	1993
The 5-HT1A receptor selective ligands, (R)-8-OH-DPAT and (S)-UH-301, differentially affect the activity of midbrain dopamine neurons. Naunyn-Schmiedeberg's archives of pharmacology, 1993, Volume: 347, Issue:4 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Action Potentials; Animals; Dopamine D2 Receptor Antagonists; Dose-Response Relationship, Drug; Electrophysiology; Injections, Intravenous; Injections, Intraventricular; Male; Neurons; Raclopride; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; Receptors, Serotonin; Salicylamides; Serotonin Antagonists; Substantia Nigra; Tegmentum Mesencephali	1993
Discriminative stimulus properties of flesinoxan: effects of enantiomers, (S)-UH301 and WAY-100635. European journal of pharmacology, 1995, Sep-15, Volume: 284, Issue:1-2 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Administration, Oral; Analgesics, Opioid; Animals; Discrimination Learning; Discrimination, Psychological; Dose-Response Relationship, Drug; Fentanyl; Generalization, Psychological; Injections, Subcutaneous; Male; Piperazines; Pyridines; Rats; Rats, Wistar; Serotonin Antagonists; Stereoisomerism	1995
The 5-HT1A receptor antagonist (S)-UH-301 augments the increase in extracellular concentrations of 5-HT in the frontal cortex produced by both acute and chronic treatment with citalopram. Naunyn-Schmiedeberg's archives of pharmacology, 1996, Volume: 353, Issue:6 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Analysis of Variance; Animals; Body Temperature; Citalopram; Extracellular Space; Male; Microdialysis; Raphe Nuclei; Rats; Rats, Wistar; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists	1996
The 5-HT1A receptor antagonist (S)-UH-301 decreases dopamine release in the rat nucleus accumbens and striatum. Journal of neural transmission (Vienna, Austria : 1996), 1996, Volume: 103, Issue:5 Topics: 3,4-Dihydroxyphenylacetic Acid; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Corpus Striatum; Dopamine; Homovanillic Acid; Hydroxyindoleacetic Acid; Injections, Subcutaneous; Male; Microdialysis; Nucleus Accumbens; Rats; Rats, Wistar; Serotonin Antagonists; Serotonin Receptor Agonists	1996
Differential serotoninergic and dopaminergic activities of the (R)- and the (S)-enantiomers of 2-(di-n-propylamino)tetralin. European journal of pharmacology, 1996, May-15, Volume: 303, Issue:3 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Behavior, Animal; Body Temperature; Dopamine; Dopamine Agonists; Male; Rats; Rats, Sprague-Dawley; Receptors, Dopamine; Receptors, Serotonin; Serotonin; Serotonin Receptor Agonists; Stereoisomerism; Tetrahydronaphthalenes	1996
Derivatives of (R)- and (S)-5-fluoro-8-hydroxy-2-(dipropylamino)tetralin: synthesis and interactions with 5-HT1A receptors. Journal of medicinal chemistry, 1996, Sep-27, Volume: 39, Issue:20 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Binding Sites; Binding, Competitive; Brain; Cyclic AMP; Molecular Structure; Rats; Receptors, Serotonin; Serotonin Antagonists; Stereoisomerism; Structure-Activity Relationship; Vasoactive Intestinal Peptide	1996
The mechanism by which the selective 5-HT1A receptor antagonist S-(-) UH 301 produces head-twitches in mice. Pharmacology, biochemistry, and behavior, 1996, Volume: 55, Issue:1 Topics: 5-Hydroxytryptophan; 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic beta-Antagonists; Animals; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Fenfluramine; Head Movements; Male; Mice; Mice, Inbred ICR; Presynaptic Terminals; Receptors, Serotonin; Selective Serotonin Reuptake Inhibitors; Serotonin Antagonists; Serotonin Receptor Agonists; Synaptic Vesicles; Tryptophan	1996
Molecular modelling of UH-301 and 5-HT(1a) receptor interactions. Protein engineering, 1996, Volume: 9, Issue:2 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Chemical Phenomena; Chemistry; Dopamine Agonists; Humans; Hydrogen Bonding; Models, Molecular; Molecular Structure; Protein Binding; Protein Conformation; Receptors, Serotonin; Serotonin Antagonists; Tetrahydronaphthalenes	1996
Synthesis and pharmacology of the enantiomers of UH301: opposing interactions with 5-HT1A receptors. Chirality, 1996, Volume: 8, Issue:8 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Behavior, Animal; Body Temperature; Chemical Phenomena; Chemistry, Physical; Crystallography, X-Ray; Dopamine; Male; Molecular Structure; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin; Serotonin Antagonists; Stereoisomerism	1996
5-HT inhibits calcium current and synaptic transmission from sensory neurons in lamprey. The Journal of neuroscience : the official journal of the Society for Neuroscience, 1997, Mar-01, Volume: 17, Issue:5 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Action Potentials; Afferent Pathways; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Depression, Chemical; Dopamine; Excitatory Amino Acid Agonists; Fluorescent Dyes; Ganglia, Spinal; Interneurons; Isoquinolines; Lampreys; Large-Conductance Calcium-Activated Potassium Channels; Locomotion; Neurons, Afferent; Potassium Channels; Potassium Channels, Calcium-Activated; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Second Messenger Systems; Serotonin; Serotonin Antagonists; Spinal Cord; Synaptic Transmission	1997
Production of serotonin syndrome by 8-OH DPAT in Cryptotis parva. Physiology & behavior, 1998, Nov-15, Volume: 65, Issue:2 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic beta-Antagonists; Animals; Dose-Response Relationship, Drug; Female; Fluorobenzenes; Injections, Intraperitoneal; Male; Phenols; Piperazines; Propranolol; Serotonin Antagonists; Serotonin Receptor Agonists; Serotonin Syndrome; Shrews	1998
Involvement of 5-HT1A receptors in the consolidation of learning in cognitively impaired rats. Annals of the New York Academy of Sciences, 1998, Dec-15, Volume: 861 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Cognition; Cognition Disorders; Learning; Piperazines; Pyridines; Rats; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Scopolamine; Serotonin Antagonists; Serotonin Receptor Agonists	1998
In vivo intrinsic efficacy of the 5-HT1A receptor antagonists NAD-299, WAY-100,635 and (S)-(-)-UH-301 at rat brain monoamine receptors. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 1999, Volume: 9, Issue:1-2 Topics: 5-Hydroxytryptophan; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Benzopyrans; Brain Chemistry; Dihydroxyphenylalanine; Dose-Response Relationship, Drug; Enzyme Inhibitors; Hippocampus; Hydrazines; Male; Neostriatum; Piperazines; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Biogenic Amine; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Antagonists	1999
Nasal absorption of (S)-UH-301 and its transport into the cerebrospinal fluid of rats. International journal of pharmaceutics, 2000, Feb-15, Volume: 195, Issue:1-2 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Absorption; Administration, Inhalation; Animals; Area Under Curve; Biological Availability; Chromatography, High Pressure Liquid; Injections, Intravenous; Male; Nasal Cavity; Rats; Rats, Sprague-Dawley; Serotonin Antagonists; Tissue Distribution	2000
Non-serotonergic potentiation by (-)-pindolol of DOI-induced forward locomotion in rats: possible involvement of beta-adrenoceptors?. Journal of neural transmission (Vienna, Austria : 1996), 2000, Volume: 107, Issue:8-9 Topics: 5-Hydroxytryptophan; 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic beta-Antagonists; Adrenergic Uptake Inhibitors; Animals; Betaxolol; Biogenic Monoamines; Dihydroxyphenylalanine; Drug Synergism; Indophenol; Male; Motor Activity; Pindolol; Piperazines; Piperidines; Propanolamines; Prosencephalon; Pyridines; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT1B; Receptors, Adrenergic, beta; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Reserpine; Serotonin Antagonists; Serotonin Receptor Agonists	2000
An integrative pharmacokinetic and pharmacodynamic study of the 5-HT1A receptor antagonist (S)-UH-301 in the rat. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2002, Volume: 12, Issue:2 Topics: 5-Hydroxytryptophan; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Area Under Curve; Body Temperature; Brain; Dose-Response Relationship, Drug; Levodopa; Male; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Antagonists	2002
Fear behavior and regional brain monoamines distribution after R(+)-8-OHDPAT and R(+)-UH-301 injections into the dorsal raphe nucleus in rats. Acta neurobiologiae experimentalis, 2002, Volume: 62, Issue:2 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Behavior, Animal; Biogenic Monoamines; Brain; Fear; Injections; Male; Raphe Nuclei; Rats; Rats, Wistar; Serotonin Antagonists; Serotonin Receptor Agonists; Tissue Distribution	2002
The 5-HT(1A) receptor active compounds (R)-8-OH-DPAT and (S)-UH-301 modulate auditory evoked EEG responses in rats. Amino acids, 2006, Volume: 31, Issue:4 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamine; Animals; Electroencephalography; Evoked Potentials, Auditory; Male; Motor Activity; Random Allocation; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1A; Serotonin; Serotonin 5-HT1 Receptor Agonists; Serotonin 5-HT1 Receptor Antagonists; Serotonin Antagonists; Serotonin Receptor Agonists	2006