8-hydroxy-2-(di-n-propylamino)tetralin has been researched along with spiroxatrine in 23 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (30.43) | 18.7374 |
| 1990's | 16 (69.57) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Audinot, V; Chaput, C; Conte, C; Gavaudan, S; Millan, MJ; Newman-Tancredi, A; Touzard, M; Verrièle, L | 1 |
| Miletic, V; Tan, H | 1 |
| Carli, M; Lazarova, M; Samanin, R; Tatarczynska, E | 1 |
| Borbe, HO; Metzenauer, P; Szelenyi, I | 1 |
| Singer, EA; Valenta, B | 1 |
| Drobny, H; Kotai, E; Singer, EA; Valenta, B; Weisz, E | 1 |
| Kalkman, HO; Soar, J | 1 |
| Barrett, JE; Foust, MJ; Harrod, C; Hoffmann, SM; Olmstead, SN; Weissman, BA | 1 |
| Li, TK; Lumeng, L; McBride, WJ; Murphy, JM | 1 |
| Beller, KD; Kolassa, N; Sanders, KH | 1 |
| Beller, KD; Bischler, P; Kolassa, N; Sanders, KH | 1 |
| Lambert, G; Monroe, PJ; Nelson, DL; Yamamura, HI | 1 |
| Herrick-Davis, K; Titeler, M | 1 |
| Anderson, EG; Marszalec, W; Scroggs, RS | 1 |
| Brikas, P; Bueno, L; Fioramonti, J | 1 |
| Anwyl, R; Manahan-Vaughan, D; Rowan, MJ | 2 |
| Dakshinamurti, K; Sharma, SK | 2 |
| Crick, H; Manuel, NA; Wallis, DI | 1 |
| Hayataka, K; O'Connor, MF; Parker, KK; Weber, JT | 1 |
| Honda, M; Ono, H | 1 |
| Chu, TC; Ogidigben, MJ; Potter, DE | 1 |
1 review(s) available for 8-hydroxy-2-(di-n-propylamino)tetralin and spiroxatrine
| Article | Year |
|---|---|
Involvement of brain 5-HT1A receptors in the hypotensive response to urapidil.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic alpha-Antagonists; Animals; Antihypertensive Agents; Blood Pressure; Brain Stem; Cats; Dioxanes; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Female; Heart Rate; Infusions, Intravenous; Male; Piperazines; Receptors, Serotonin; Spiro Compounds; Tetrahydronaphthalenes | 1989 |
22 other study(ies) available for 8-hydroxy-2-(di-n-propylamino)tetralin and spiroxatrine
| Article | Year |
|---|---|
Agonist and antagonist actions of antipsychotic agents at 5-HT1A receptors: a [35S]GTPgammaS binding study.
Topics: Animals; Antipsychotic Agents; CHO Cells; Cricetinae; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Agents; Sulfur Radioisotopes | 1998 |
Diverse actions of 5-hydroxytryptamine on frog spinal dorsal horn neurons in vitro.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Dioxanes; Electric Stimulation; Evoked Potentials; Female; In Vitro Techniques; Ketanserin; Kinetics; Male; Membrane Potentials; Methysergide; Mianserin; Neurons; Rana pipiens; Serotonin; Serotonin Antagonists; Spinal Cord; Spiro Compounds; Synapses; Tetrodotoxin; Tropanes | 1992 |
Stimulation of 5-HT1A receptors in the dorsal hippocampus impairs acquisition and performance of a spatial task in a water maze.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Depression, Chemical; Dioxanes; Discrimination Learning; Dopamine Antagonists; Dose-Response Relationship, Drug; Hippocampus; Male; Psychomotor Performance; Rats; Serotonin Receptor Agonists; Space Perception; Spiro Compounds; Stereotaxic Techniques | 1992 |
5-HT1A-agonistic properties of naftopidil, a novel antihypertensive drug.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antihypertensive Agents; Cats; Dioxanes; Dopamine Antagonists; Female; Hemodynamics; Male; Naphthalenes; Piperazines; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, Serotonin; Spiro Compounds; Tetrahydronaphthalenes | 1991 |
Hypotensive effects of 8-hydroxy-2-(di-n-propylamino)tetralin and 5-methylurapidil following stereotaxic microinjection into the ventral medulla of the rat.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic beta-Antagonists; Animals; Blood Pressure; Dioxanes; Dopamine Antagonists; Heart Rate; Male; Medulla Oblongata; Microinjections; Naphthalenes; Piperazines; Prazosin; Rats; Rats, Inbred Strains; Spiperone; Spiro Compounds; Stereotaxic Techniques; Tetrahydronaphthalenes | 1990 |
[Central presynaptic receptors].
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antihypertensive Agents; Blood Pressure; Brain; Central Nervous System; Dihydroxytryptamines; Dioxanes; Dopamine Antagonists; Heart Rate; Neurons; Neurotransmitter Agents; Norepinephrine; Rabbits; Rats; Receptors, Adrenergic, alpha; Receptors, Serotonin; Serotonin Antagonists; Spinal Cord; Spiro Compounds; Tetrahydronaphthalenes | 1990 |
Determination of the 5-HT receptor subtype involved in 8-OH-DPAT-induced hyperlocomotion: potential difficulties arising from inadequate pharmacological tools.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Buspirone; Dioxanes; Haloperidol; Male; Motor Activity; Pindolol; Pyrimidines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin Antagonists; Spiro Compounds; Tetrahydronaphthalenes | 1990 |
Behavioral and neurochemical effects of the serotonin (5-HT)1A receptor ligand spiroxatrine.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Behavior, Animal; Biogenic Monoamines; Brain Chemistry; Buspirone; Columbidae; Conditioning, Operant; Dioxanes; Dioxins; Dopamine Antagonists; Piribedil; Receptors, Serotonin; Spiro Compounds; Tetrahydronaphthalenes | 1989 |
Spiroxatrine augments fluoxetine-induced reduction of ethanol intake by the P line of rats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Alcohol Drinking; Animals; Dioxanes; Dioxins; Dopamine Antagonists; Female; Fluoxetine; Rats; Spiro Compounds; Tetrahydronaphthalenes | 1989 |
Interaction of urapidil with brain serotonin-1A receptors increases the blood pressure reduction due to peripheral alpha-adrenoceptor inhibition.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic alpha-Antagonists; Animals; Antihypertensive Agents; Blood Pressure; Cats; Dioxanes; Female; Male; Piperazines; Receptors, Serotonin; Serotonin Antagonists; Spiro Compounds; Tetrahydronaphthalenes | 1988 |
[3H]spiroxatrine labels a serotonin1A-like site in the rat hippocampus.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Binding, Competitive; Cell Membrane; Dioxanes; Dioxins; Dopamine; Guanosine Triphosphate; Haloperidol; Hippocampus; Male; Norepinephrine; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin; Spiperone; Spiro Compounds; Tetrahydronaphthalenes; Tritium | 1987 |
[3H]spiroxatrine: a 5-HT1A radioligand with agonist binding properties.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adenylyl Imidodiphosphate; Animals; Binding, Competitive; Cell Membrane; Dioxanes; Dioxins; Guanylyl Imidodiphosphate; Hippocampus; Kinetics; Male; Rats; Rats, Inbred Strains; Receptors, Serotonin; Spiro Compounds; Tetrahydronaphthalenes; Tritium | 1988 |
Serotonin-induced reduction of the calcium-dependent plateau in frog dorsal root ganglion cells is blocked by serotonergic agents acting at 5-hydroxytryptamine1A sites.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Action Potentials; Animals; Calcium; Dioxanes; Ganglia, Spinal; Methiothepin; Rana catesbeiana; Receptors, Serotonin; Serotonin; Spiperone; Spiro Compounds; Tetrahydronaphthalenes | 1988 |
Types of serotonergic receptors involved in the control of reticulo-ruminal myoelectric activity in sheep.
Topics: 5-Methoxytryptamine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Benzimidazoles; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Dioxanes; Dopamine Antagonists; Electromyography; Female; Gastrointestinal Motility; Granisetron; Injections, Intravenous; Injections, Intraventricular; Microelectrodes; Receptors, Serotonin; Reticulum; Ritanserin; Rumen; Serotonin; Serotonin Receptor Agonists; Sheep; Spiro Compounds | 1994 |
5-HT1A receptor-mediated inhibition in the hippocampus of the alert rat--effects of repeated gepirone treatment.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Action Potentials; Animals; Anti-Anxiety Agents; Binding Sites; Dioxanes; Dioxins; Dopamine Antagonists; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Electrodes; Evoked Potentials; Hippocampus; Male; Pyrimidines; Rats; Rats, Wistar; Receptors, Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Spiro Compounds | 1994 |
Effects of serotonergic agents on plasma prolactin levels in pyridoxine-deficient adult male rats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Dioxanes; Dopamine Antagonists; Hypothalamus; Male; Prolactin; Pyridoxal Phosphate; Pyridoxine; Rats; Rats, Sprague-Dawley; Serotonin; Spiro Compounds; Tetrahydronaphthalenes; Vitamin B 6 Deficiency | 1994 |
Suppression of domoic acid induced seizures by 8-(OH)-DPAT.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Dioxanes; Dopamine Antagonists; Dose-Response Relationship, Drug; Electroencephalography; Fourier Analysis; Kainic Acid; Male; Microinjections; Neuromuscular Depolarizing Agents; Rats; Rats, Sprague-Dawley; Seizures; Spiro Compounds | 1993 |
Ketanserin-sensitive depressant actions of 5-HT receptor agonists in the neonatal rat spinal cord.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Animals, Newborn; Depression, Chemical; Dioxanes; Dopamine Antagonists; Drug Interactions; Female; Ketanserin; Male; Motor Neurons; Oxadiazoles; Pindolol; Piperazines; Propranolol; Rats; Rats, Wistar; Receptors, Serotonin; Reflex, Monosynaptic; Serotonin; Serotonin Antagonists; Spinal Cord; Spiro Compounds; Sumatriptan | 1995 |
The azapirone metabolite 1-(2-pyrimidinyl)piperazine depresses excitatory synaptic transmission in the hippocampus of the alert rat via 5-HT1A receptors.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Action Potentials; Animals; Buspirone; Dioxanes; Dose-Response Relationship, Drug; Hippocampus; Male; Rats; Rats, Wistar; Receptors, Serotonin; Spiro Compounds; Synaptic Transmission | 1995 |
Rabbit cerebral cortex 5HT1a receptors.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Binding Sites; Binding, Competitive; Cerebral Cortex; CHO Cells; Cricetinae; Dioxanes; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Kinetics; Propranolol; Rabbits; Rats; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Receptor Agonists; Sesquiterpenes; Spiro Compounds; Tritium | 1997 |
Differential effects of (R)- and (S)-8-hydroxy-2-(di-n-propylamino)tetralin on the monosynaptic spinal reflex in rats.
Topics: 5,6-Dihydroxytryptamine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic alpha-Antagonists; Animals; Decerebrate State; Dioxanes; Dose-Response Relationship, Drug; Male; Norepinephrine; Piperazines; Prazosin; Rats; Rats, Wistar; Reflex, Monosynaptic; Serotonin; Serotonin Agents; Serotonin Antagonists; Serotonin Receptor Agonists; Spinal Cord; Spiro Compounds; Stereoisomerism | 1999 |
8OH-DPAT-Induced ocular hypotension: sites and mechanisms of action.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Ciliary Body; Cyclic AMP; Dioxanes; Dopamine Antagonists; Dose-Response Relationship, Drug; Intraocular Pressure; Iris; Norepinephrine; Ocular Hypertension; Rabbits; Serotonin Receptor Agonists; Spiperone; Spiro Compounds | 1999 |