8-hydroxy-2-(di-n-propylamino)tetralin and sertraline

8-hydroxy-2-(di-n-propylamino)tetralin has been researched along with sertraline in 14 studies

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's8 (57.14)18.2507
2000's3 (21.43)29.6817
2010's3 (21.43)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Buck, LB; Petrascheck, M; Ye, X1
Maj, J; Moryl, E1
Grealy, M; O'Donnell, JM1
Simansky, KJ; Vaidya, AH1
Kelly, JP; Leonard, BE1
Auerbach, SB; Rutter, JJ1
Hyttel, J; Sánchez, C1
Clarke, T; Rollema, H; Schulz, DW; Sprouse, JS1
Connor, TJ; Dredge, K; Harkin, A; Kelly, JP; Leonard, BE; McNamara, M; Redmond, A1
Fornal, CA; Jacobs, BL; Metzler, CW; Mirescu, C; Stein, SK1
Nogueira, RL; Zangrossi, H; Zanoveli, JM1
Chevarin, C; Du, X; Hannan, AJ; Lanfumey, L; Leang, L; Pang, TY; Renoir, T; Zajac, MS1
Alvarado, G; Artigas, F; Bortolozzi, A; Carmona, MC; Castañé, A; Cortés, R; Fernández, G; Ferrés-Coy, A; Montefeltro, A; Perales, JC; Santana, N; Semakova, J; Toth, M1
Davoudi, S; Heydari, A1

Other Studies

14 other study(ies) available for 8-hydroxy-2-(di-n-propylamino)tetralin and sertraline

ArticleYear
An antidepressant that extends lifespan in adult Caenorhabditis elegans.
    Nature, 2007, Nov-22, Volume: 450, Issue:7169

    Topics: Aging; Animals; Antidepressive Agents; Caenorhabditis elegans; Caloric Restriction; Humans; Longevity; Methiothepin; Mianserin; Octopamine; Receptors, Biogenic Amine; Receptors, Serotonin, 5-HT4; Serotonin; Serotonin 5-HT4 Receptor Antagonists; Serotonin Antagonists; Signal Transduction; Starvation

2007
Effects of sertraline and citalopram given repeatedly on the responsiveness of 5-HT receptor subpopulations.
    Journal of neural transmission. General section, 1992, Volume: 88, Issue:2

    Topics: 1-Naphthylamine; 5-Hydroxytryptophan; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Behavior, Animal; Body Temperature; Citalopram; Drug Interactions; Exploratory Behavior; Fenfluramine; Male; Motor Activity; Piperazines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Serotonin; Sertraline; Tetrahydronaphthalenes

1992
Neuroendocrine response to clonidine and 8-OH-DPAT in rats following chronic administration of desipramine or sertraline.
    British journal of pharmacology, 1992, Volume: 105, Issue:4

    Topics: 1-Naphthylamine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Behavior, Animal; Cerebral Cortex; Clonidine; Corticosterone; Desipramine; Dihydroalprenolol; Male; Neurosecretory Systems; Prolactin; Rats; Rats, Inbred Strains; Receptors, Serotonin; Sertraline; Tetrahydronaphthalenes

1992
Behavioral mechanisms for the anorectic action of the serotonin (5-HT) uptake inhibitor sertraline in rats: comparison with directly acting 5-HT agonists.
    Brain research bulletin, 1990, Volume: 25, Issue:6

    Topics: 1-Naphthylamine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Appetite; Eating; Feeding Behavior; Indoles; Male; Piperazines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Satiation; Sertraline; Tetrahydronaphthalenes

1990
The effect of tianeptine and sertraline in three animal models of depression.
    Neuropharmacology, 1994, Volume: 33, Issue:8

    Topics: 1-Naphthylamine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antidepressive Agents; Antidepressive Agents, Tricyclic; Behavior, Animal; Body Temperature; Corticosterone; Depressive Disorder; Hydroxyindoleacetic Acid; Hypothalamus; Indoles; Male; Motor Activity; Neurotransmitter Agents; Olfactory Bulb; Rats; Rats, Sprague-Dawley; Sertraline; Thiazepines

1994
Acute uptake inhibition increases extracellular serotonin in the rat forebrain.
    The Journal of pharmacology and experimental therapeutics, 1993, Volume: 265, Issue:3

    Topics: 1-Naphthylamine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Corpus Striatum; Diencephalon; Fenfluramine; Fluoxetine; Hydroxyindoleacetic Acid; Male; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Serotonin; Sertraline

1993
Isolation-induced aggression in mice: effects of 5-hydroxytryptamine uptake inhibitors and involvement of postsynaptic 5-HT1A receptors.
    European journal of pharmacology, 1994, Nov-03, Volume: 264, Issue:3

    Topics: 1-Naphthylamine; 5-Hydroxytryptophan; 8-Hydroxy-2-(di-n-propylamino)tetralin; Aggression; Analysis of Variance; Animals; Behavior, Animal; Brain; Citalopram; Dose-Response Relationship, Drug; Fenclonine; Fluoxetine; Fluvoxamine; Male; Mice; Paroxetine; Penbutolol; Piperidines; Rats; Rats, Wistar; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Selective Serotonin Reuptake Inhibitors; Sertraline; Synaptosomes

1994
Combined administration of a 5-hydroxytryptamine (5-HT)1D antagonist and a 5-HT reuptake inhibitor synergistically increases 5-HT release in guinea pig hypothalamus in vivo.
    Journal of neurochemistry, 1996, Volume: 67, Issue:5

    Topics: 1-Naphthylamine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Drug Synergism; Guinea Pigs; Hydroxyindoleacetic Acid; Hypothalamus; Indoles; Kinetics; Neurons; Oxadiazoles; Piperazines; Pyridines; Receptor, Serotonin, 5-HT1D; Receptors, Serotonin; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Antagonists; Sertraline

1996
Activity and onset of action of reboxetine and effect of combination with sertraline in an animal model of depression.
    European journal of pharmacology, 1999, Jan-08, Volume: 364, Issue:2-3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amygdala; Analgesics; Animals; Antidepressive Agents; Body Temperature; Clonidine; Depression; Disease Models, Animal; Drug Therapy, Combination; Exploratory Behavior; Hydroxyindoleacetic Acid; Male; Morpholines; Motor Activity; Olfactory Bulb; Rats; Rats, Sprague-Dawley; Reboxetine; Serotonin Receptor Agonists; Sertraline; Swimming

1999
Effects of standardized extracts of St. John's wort on the single-unit activity of serotonergic dorsal Raphe neurons in awake cats: comparisons with fluoxetine and sertraline.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2001, Volume: 25, Issue:6

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Cats; Electrophysiology; Fluoxetine; Hypericum; Male; Membrane Potentials; Neurons; Piperazines; Plant Extracts; Pyridines; Raphe Nuclei; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Sertraline

2001
Enhanced reactivity of 5-HT1A receptors in the rat dorsal periaqueductal gray matter after chronic treatment with fluoxetine and sertraline: evidence from the elevated T-maze.
    Neuropharmacology, 2007, Volume: 52, Issue:4

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Analysis of Variance; Animals; Behavior, Animal; Drug Interactions; Fluoxetine; Male; Maze Learning; Periaqueductal Gray; Rats; Rats, Wistar; Reaction Time; Receptor, Serotonin, 5-HT1A; Selective Serotonin Reuptake Inhibitors; Sertraline

2007
Sexually dimorphic serotonergic dysfunction in a mouse model of Huntington's disease and depression.
    PloS one, 2011, Volume: 6, Issue:7

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Behavior, Animal; Depression; Disease Models, Animal; Feeding Behavior; Female; Gene Expression Regulation; Huntington Disease; Hydroxyindoleacetic Acid; Hyperthermia, Induced; Male; Mice; Mutation; Raphe Nuclei; Receptor, Serotonin, 5-HT1A; Receptor, Serotonin, 5-HT2A; Serotonin; Sertraline; Sex Characteristics; Swimming

2011
Selective siRNA-mediated suppression of 5-HT1A autoreceptors evokes strong anti-depressant-like effects.
    Molecular psychiatry, 2012, Volume: 17, Issue:6

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Administration, Intranasal; Animals; Antidepressive Agents; Autoreceptors; Depression; Disease Models, Animal; Drug Combinations; Drug Design; Fluoxetine; Hippocampus; Hypothermia; Infusions, Intraventricular; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Prefrontal Cortex; Receptor, Serotonin, 5-HT1A; RNA, Small Interfering; Serotonergic Neurons; Sertraline

2012
The effect of sertraline and 8-OH-DPAT on the PTZ_induced seizure threshold: Role of the nitrergic system.
    Seizure, 2017, Volume: 45

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Analysis of Variance; Animals; Convulsants; Disease Models, Animal; Dose-Response Relationship, Drug; Male; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide; Pentylenetetrazole; Piperazines; Pyridines; Seizures; Selective Serotonin Reuptake Inhibitors; Serotonin Antagonists; Sertraline

2017