8-hydroxy-2-(di-n-propylamino)tetralin and scopolamine hydrobromide

8-hydroxy-2-(di-n-propylamino)tetralin has been researched along with scopolamine hydrobromide in 27 studies

Research

Studies (27)

TimeframeStudies, this research(%)All Research%
pre-19901 (3.70)18.7374
1990's17 (62.96)18.2507
2000's7 (25.93)29.6817
2010's2 (7.41)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Berardi, F; Colabufo, NA; Giudice, G; Govoni, S; Lucchi, L; Perrone, R; Tortorella, V1
Kameyama, T; Kawashima, K; Nabeshima, T1
Buhot, MC; Naïli, S1
Riekkinen, P1
Cole, BJ; Jones, GH; Turner, JD1
Ishimoto, Y; Kamata, T; Katoh, S; Kawakubo, H; Mochizuki, D; Nagatani, T; Sasaki, Y; Takagi, S; Yamaura, Y1
Buhot, MC; Naïli, S; Patra, SK1
Dourish, CT; McLenachan, AP; Stanhope, KJ1
Riekkinen, M; Riekkinen, P; Sirviö, J; Toivanen, T1
Hutson, PH; Patel, S1
Cassel, JC; Erb, C; Jeltsch, H; Klein, J; Köppen, A; Löffelholz, K1
Daws, LC; Janowsky, DS; Orbach, J; Overstreet, DH; Schiller, GD1
Bonalumi, P; Carli, M; Samanin, R1
Barrett, JE; Vanover, KE1
Hong, E; Meneses, A; Terrón, JA1
Hong, E; Meneses, A1
Chau, D; Hoebel, BG; Kosloff, RA; Rada, PV1
Kaneko, T; Kikusui, T; Tonohiro, T1
Pache, DM; Sewell, RD; Spencer, PS1
Balducci, C; Carli, M; Samanin, R1
Santucci, AC; Shaw, C1
Carli, M; Dekeyne, A; Di Cara, B; Gobert, A; Jaffard, R; Lestage, P; Meneses, A; Millan, MJ; Mocaer, E; Peglion, JL; Porsolt, R; Rivet, JM; Roux, S1
Elvander, E; Lüttgen, M; Madjid, N; Ogren, SO1
Cheng, HY; Hsieh, CC; Hsieh, MT; Lin, YT; Lu, MC; Peng, WH; Wu, CR1
Meneses, A; Perez-García, G1
Chang, SD; Liang, KC1
Ilies, MA; John, JS; Salkovitz, M; Sanku, RKK; Walker, EA1

Other Studies

27 other study(ies) available for 8-hydroxy-2-(di-n-propylamino)tetralin and scopolamine hydrobromide

ArticleYear
New sigma and 5-HT1A receptor ligands: omega-(tetralin-1-yl)-n-alkylamine derivatives.
    Journal of medicinal chemistry, 1996, Jan-05, Volume: 39, Issue:1

    Topics: Analgesics, Opioid; Animals; Binding Sites; Brain; Guinea Pigs; Magnetic Resonance Spectroscopy; Male; Pentazocine; Phencyclidine; Piperazines; Propylamines; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; Receptors, Phencyclidine; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Receptors, sigma; Serotonin; Serotonin Receptor Agonists; Structure-Activity Relationship; Tetrahydronaphthalenes

1996
Effect of minaprine on cycloheximide-induced amnesia in mice.
    European journal of pharmacology, 1989, Oct-10, Volume: 169, Issue:2-3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amnesia; Animals; Avoidance Learning; Cycloheximide; Drug Interactions; Male; Mice; p-Chloroamphetamine; Physostigmine; Piperidines; Pyridazines; Ritanserin; Scopolamine; Tetrahydronaphthalenes

1989
Changes in exploratory activity following stimulation of hippocampal 5-HT1A and 5-HT1B receptors in the rat.
    Hippocampus, 1995, Volume: 5, Issue:3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Behavior, Animal; Exploratory Behavior; Habituation, Psychophysiologic; Hippocampus; Male; Motor Activity; Pyridines; Pyrroles; Rats; Rats, Inbred Strains; Receptors, Serotonin; Scopolamine; Serotonin Receptor Agonists; Space Perception; Stimulation, Chemical

1995
5-HT1A and muscarinic acetylcholine receptors jointly regulate passive avoidance behavior.
    European journal of pharmacology, 1994, Sep-01, Volume: 262, Issue:1-2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Avoidance Learning; Behavior, Animal; Choline O-Acetyltransferase; Drug Interactions; Ketanserin; Male; Motor Activity; Muscarinic Agonists; Pain Measurement; Pain Threshold; Rats; Rats, Wistar; Receptors, Muscarinic; Receptors, Serotonin; Scopolamine; Septal Nuclei; Serotonin Receptor Agonists

1994
5-HT1A receptor agonists improve the performance of normal and scopolamine-impaired rats in an operant delayed matching to position task.
    Psychopharmacology, 1994, Volume: 116, Issue:2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Conditioning, Operant; Male; Memory, Short-Term; Piperazines; Psychomotor Performance; Pyrimidines; Rats; Rats, Wistar; Scopolamine; Serotonin Antagonists; Serotonin Receptor Agonists; Space Perception

1994
(R)-1,2,3,4-tetrahydro[1]benzothieno[2,3-c]pyridines: novel optically active compounds with strong 5-HT1A receptor binding ability exhibiting anticonflict activity and lessening of memory impairment.
    Journal of medicinal chemistry, 1993, Nov-12, Volume: 36, Issue:23

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amnesia; Animals; Anti-Anxiety Agents; Avoidance Learning; Conflict, Psychological; Male; Mice; Molecular Structure; Pyridines; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptors, Serotonin; Scopolamine; Stereoisomerism; Structure-Activity Relationship; Thienopyridines; Thiophenes

1993
Spatial memory deficits following stimulation of hippocampal 5-HT1B receptors in the rat.
    European journal of pharmacology, 1995, Oct-24, Volume: 285, Issue:3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Behavior, Animal; Handling, Psychological; Hippocampus; Injections; Male; Maze Learning; Memory Disorders; Memory, Short-Term; Muscarinic Antagonists; Pyridines; Pyrroles; Rats; Receptors, Serotonin; Scopolamine; Serotonin Receptor Agonists; Space Perception

1995
Dissociation between cognitive and motor/motivational deficits in the delayed matching to position test: effects of scopolamine, 8-OH-DPAT and EAA antagonists.
    Psychopharmacology, 1995, Volume: 122, Issue:3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Cognition; Conditioning, Operant; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Male; Motor Activity; Muscarinic Antagonists; Pipecolic Acids; Rats; Rats, Sprague-Dawley; Scopolamine; Scopolamine Derivatives; Serotonin Receptor Agonists

1995
Combined treatment with a 5HT1A receptor agonist and a muscarinic acetylcholine receptor antagonist disrupts water maze navigation behavior.
    Psychopharmacology, 1995, Volume: 122, Issue:2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Cues; Fenclonine; Male; Maze Learning; Muscarinic Antagonists; Psychomotor Performance; Rats; Rats, Wistar; Receptors, Muscarinic; Scopolamine; Serotonin Agents; Serotonin Receptor Agonists; Space Perception

1995
Effects of galanin on 8-OH-DPAT induced decrease in body temperature and brain 5-hydroxytryptamine metabolism in the mouse.
    European journal of pharmacology, 1996, Dec-19, Volume: 317, Issue:2-3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Body Temperature Regulation; Brain Chemistry; Cerebral Cortex; Galanin; Injections, Intraventricular; Male; Mice; Mice, Inbred Strains; Muscarinic Antagonists; Piperazines; Potassium Channels; Pyridines; Receptors, Galanin; Receptors, Gastrointestinal Hormone; Receptors, Serotonin; Scopolamine; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists

1996
Modulation of hippocampal acetylcholine release after fimbria-fornix lesions and septal transplantation in rats.
    Neuroscience letters, 1997, Aug-01, Volume: 231, Issue:1

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Acetylcholine; Animals; Brain Tissue Transplantation; Cholinergic Fibers; Female; Hippocampus; Microdialysis; Muscarinic Antagonists; Neural Pathways; Raphe Nuclei; Rats; Rats, Inbred Strains; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Scopolamine; Septal Nuclei

1997
Cholinergic/serotonergic interactions in hypothermia: implications for rat models of depression.
    Pharmacology, biochemistry, and behavior, 1998, Volume: 59, Issue:4

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aging; Animals; Body Temperature Regulation; Depressive Disorder; Disease Models, Animal; Female; Hypothermia, Induced; Male; Muscarinic Agonists; Muscarinic Antagonists; Oxotremorine; Parasympathetic Nervous System; Rats; Rats, Inbred Strains; Receptors, Serotonin; Scopolamine; Serotonin; Serotonin Receptor Agonists

1998
Stimulation of 5-HT1A receptors in the dorsal raphe reverses the impairment of spatial learning caused by intrahippocampal scopolamine in rats.
    The European journal of neuroscience, 1998, Volume: 10, Issue:1

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Behavior, Animal; Hippocampus; Male; Maze Learning; Microinjections; Muscarinic Antagonists; Piperazines; Pyridines; Raphe Nuclei; Rats; Rats, Inbred Strains; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Scopolamine; Serotonin Antagonists; Serotonin Receptor Agonists; Spatial Behavior

1998
An automated learning and memory model in mice: pharmacological and behavioral evaluation of an autoshaped response.
    Behavioural pharmacology, 1998, Volume: 9, Issue:3

    Topics: 4-Aminopyridine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Indoles; Learning; Male; Memory; Mice; Models, Psychological; Muscarinic Antagonists; Pyridines; Scopolamine; Serotonin Receptor Agonists

1998
Involvement of 5-HT1A receptors in the consolidation of learning in cognitively impaired rats.
    Annals of the New York Academy of Sciences, 1998, Dec-15, Volume: 861

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Cognition; Cognition Disorders; Learning; Piperazines; Pyridines; Rats; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Scopolamine; Serotonin Antagonists; Serotonin Receptor Agonists

1998
5-HT1A receptors modulate the consolidation of learning in normal and cognitively impaired rats.
    Neurobiology of learning and memory, 1999, Volume: 71, Issue:2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Cholinergic Antagonists; Cognition Disorders; Conditioning, Psychological; Excitatory Amino Acid Antagonists; Learning; Male; p-Chloroamphetamine; Rats; Rats, Wistar; Receptors, Neurotransmitter; Receptors, Presynaptic; Scopolamine; Serotonin Antagonists

1999
Cholinergic, M1 receptors in the nucleus accumbens mediate behavioral depression. A possible downstream target for fluoxetine.
    Annals of the New York Academy of Sciences, 1999, Jun-29, Volume: 877

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Acetylcholine; Animals; Arecoline; Depression; Female; Fluoxetine; Microinjections; Motor Activity; Nucleus Accumbens; Pirenzepine; Posture; Rats; Rats, Sprague-Dawley; Receptor, Muscarinic M1; Receptors, Muscarinic; Scopolamine; Swimming

1999
The allocentric place discrimination task is selectively and highly dependent on the central muscarinic system in rats.
    Pharmacology, biochemistry, and behavior, 2000, Jan-01, Volume: 65, Issue:1

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Brain; Diazepam; Discrimination Learning; Dizocilpine Maleate; Flumazenil; Male; Mecamylamine; Ondansetron; Rats; Rats, Inbred F344; Receptors, Muscarinic; Scopolamine; Swimming

2000
Detecting drug effects on short-term memory function using a combined delayed matching and non-matching to position task.
    Journal of pharmacological and toxicological methods, 1999, Volume: 41, Issue:4

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Behavior, Animal; Conditioning, Operant; Dose-Response Relationship, Drug; Male; Memory Disorders; Memory, Short-Term; Muscarinic Antagonists; Psychological Tests; Rats; Rats, Wistar; Scopolamine; Serotonin Receptor Agonists; Time Factors

1999
Low doses of 8-OH-DPAT prevent the impairment of spatial learning caused by intrahippocampal scopolamine through 5-HT(1A) receptors in the dorsal raphe.
    British journal of pharmacology, 2000, Volume: 131, Issue:2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Discrimination Learning; Hippocampus; Male; Muscarinic Antagonists; Piperazines; Pyridines; Raphe Nuclei; Rats; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Scopolamine; Serotonin Antagonists; Serotonin Receptor Agonists; Spatial Behavior

2000
Peripheral 8-OH-DPAT and scopolamine infused into the frontal cortex produce passive avoidance retention impairments in rats.
    Neurobiology of learning and memory, 2003, Volume: 79, Issue:2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Acetylcholine; Animals; Avoidance Learning; Frontal Lobe; Male; Muscarinic Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Retention, Psychology; Scopolamine; Serotonin; Serotonin Receptor Agonists; Stereotaxic Techniques

2003
The serotonin1A receptor partial agonist S15535 [4-(benzodioxan-5-yl)1-(indan-2-yl)piperazine] enhances cholinergic transmission and cognitive function in rodents: a combined neurochemical and behavioral analysis.
    The Journal of pharmacology and experimental therapeutics, 2004, Volume: 311, Issue:1

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Acetylcholine; Aging; Amnesia; Animals; Dialysis; Discrimination Learning; Drug Interactions; Hippocampus; Male; Maze Learning; Memory; Mice; Mice, Inbred C57BL; Piperazines; Prefrontal Cortex; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT1A; Recognition, Psychology; Scopolamine; Serotonin Receptor Agonists; Spatial Behavior

2004
Analysis of the role of 5-HT1A receptors in spatial and aversive learning in the rat.
    Neuropharmacology, 2005, Volume: 48, Issue:6

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Analysis of Variance; Animals; Avoidance Learning; Behavior, Animal; Benzopyrans; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Antagonists; Male; Maze Learning; Muscarinic Antagonists; Piperazines; Pyridines; Rats; Rats, Sprague-Dawley; Reaction Time; Receptor, Serotonin, 5-HT1A; Scopolamine; Serotonin Antagonists; Serotonin Receptor Agonists; Spatial Behavior; Time Factors

2005
Ameliorating effect of emodin, a constitute of Polygonatum multiflorum, on cycloheximide-induced impairment of memory consolidation in rats.
    Journal of ethnopharmacology, 2007, Jul-25, Volume: 112, Issue:3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Administration, Oral; Animals; Baclofen; Bicuculline; Cycloheximide; Dose-Response Relationship, Drug; Emodin; GABA Agonists; GABA Antagonists; Injections, Subcutaneous; Learning; Male; Memory; Memory Disorders; Plant Roots; Polygonatum; Protein Synthesis Inhibitors; Rats; Rats, Sprague-Dawley; Ritanserin; Scopolamine; Serotonin 5-HT1 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists

2007
Ex vivo study of 5-HT(1A) and 5-HT(7) receptor agonists and antagonists on cAMP accumulation during memory formation and amnesia.
    Behavioural brain research, 2008, Dec-16, Volume: 195, Issue:1

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amnesia; Animals; Behavior, Animal; Cholinergic Antagonists; Cyclic AMP; Dizocilpine Maleate; Enzyme-Linked Immunosorbent Assay; Excitatory Amino Acid Antagonists; Hippocampus; Learning; Male; Memory; Phenols; Piperazines; Pyrazoles; Pyridines; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT1A; Receptors, Serotonin; Scopolamine; Serotonin Antagonists; Serotonin Receptor Agonists; Sulfonamides; Tetrahydronaphthalenes

2008
Roles of hippocampal GABA(A) and muscarinic receptors in consolidation of context memory and context-shock association in contextual fear conditioning: a double dissociation study.
    Neurobiology of learning and memory, 2012, Volume: 98, Issue:1

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Association Learning; Conditioning, Psychological; Electroshock; Excitatory Amino Acid Antagonists; Fear; GABA-A Receptor Agonists; Hippocampus; Male; Memory; Muscarinic Antagonists; Muscimol; Rats; Rats, Wistar; Receptors, GABA-A; Receptors, Muscarinic; Scopolamine; Serotonin Receptor Agonists; Valine

2012
Potential learning and memory disruptors and enhancers in a simple, 1-day operant task in mice.
    Behavioural pharmacology, 2018, Volume: 29, Issue:6

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adjuvants, Anesthesia; Animals; Conditioning, Operant; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Activators; Excitatory Amino Acid Antagonists; Ketamine; Learning Disabilities; Male; Memory Disorders; Mice; Mice, Inbred Strains; Reinforcement, Psychology; Scopolamine; Serotonin Receptor Agonists

2018