8-hydroxy-2-(di-n-propylamino)tetralin has been researched along with sb 269970 in 32 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 23 (71.88) | 29.6817 |
| 2010's | 9 (28.13) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Glennon, RA | 1 |
| Berardi, F; Colabufo, NA; Contino, M; Lacivita, E; Leopoldo, M; Perrone, R | 1 |
| Berardi, F; Caccia, S; Colabufo, NA; Contino, M; De Giorgio, P; Fracasso, C; Guzzetti, S; Lacivita, E; Leopoldo, M; Perrone, R | 1 |
| Bienkowski, P; Bucki, A; Jaśkowska, J; Kazek, G; Kowalski, P; Kołaczkowski, M; Marcinkowska, M; Mierzejewski, P; Mitka, K; Pawłowski, M; Siwek, A; Wasik, A; Wesołowska, A | 1 |
| Cagnotto, A; Intagliata, S; Modica, MN; Pittalà, V; Romeo, G; Salerno, L; Salmona, M; Siracusa, MA | 2 |
| Cagnotto, A; Intagliata, S; Kurczab, R; Modica, MN; Pittalà, V; Romeo, G; Salerno, L; Salmona, M; Siracusa, MA | 1 |
| Amata, E; Cagnotto, A; Candido, M; Floresta, G; Intagliata, S; Modica, MN; Pittalà, V; Rescifina, A; Romeo, G; Salerno, L; Salmona, M | 1 |
| Lepailleur, A; Rochais, C; Thirumaran, SL | 1 |
| Allen, L; Hagan, JJ; Langmead, CJ; Middlemiss, DN; Price, GW; Roberts, C | 1 |
| Honda, M; Ono, H | 1 |
| Bonaventure, P; Carruthers, N; Chai, W; Hen, R; Kwok, A; Langlois, X; Lovenberg, TW; Nepomuceno, D; Stark, K | 1 |
| Chapman, KE; Kelly, PA; Lai, M; McCormick, JA; Seckl, JR; Yau, JL | 1 |
| Bonaventure, P; Hedlund, PB; Kelly, L; Lovenberg, T; Mazur, C; Sutcliffe, JG | 1 |
| Duncan, MJ; Grear, KE; Hoskins, MA | 1 |
| Abu-Amara, M; Aldairy, C; Hagan, JJ; Siddiqui, A; Wilson, C | 1 |
| Borszcz, GS; Harte, SE; Kender, RG | 1 |
| Bobirnac, I; Dev, KK; Loetscher, E; Mahé, C; Otten, U; Schoeffter, P | 1 |
| Egashira, N; Fujioka, M; Fujiwara, M; Ishigami, N; Iwasaki, K; Matsushita, M; Mishima, K; Nishimura, R; Yano, A | 1 |
| Pericić, D; Strac, DS; Vlainić, J | 1 |
| Debonnel, G; Faure, C; Haddjeri, N; Mnie-Filali, O; Scarna, H | 1 |
| Egashira, N; Fujiwara, M; Iwasaki, K; Koushi, E; Matsuda, T; Mishima, K; Shoyama, Y | 1 |
| Javid, FA; Naylor, RJ | 1 |
| Shaharyar, S; Siddiqui, A | 1 |
| Chidori, S; Egashira, N; Fujiwara, M; Hasebe, N; Higashihara, F; Iwasaki, K; Koushi, E; Matsuda, T; Mishima, K; Nishimura, R; Oishi, R | 1 |
| Fox, MA; French, HT; Huang, SJ; Jensen, CL; Murphy, DL; Stein, AR; Tolliver, TJ | 1 |
| Meneses, A; Perez-García, G | 2 |
| Bidon, O; Dutschmann, M; Koch, UR; Lalley, PM; Manzke, T; Mörschel, M; Ponimaskin, E; Richter, DW; Schlaf, G | 1 |
| Cheng, JP; Fryer, WM; Garcia, AN; Kline, AE; Shah, MA; Tay, JK; Yelleswarapu, NK | 1 |
| Baba, A; Hashimoto, H; Hayata-Takano, A; Hazama, K; Ogata, K; Seiriki, K; Shintani, N; Tajiri, M | 1 |
| Han, SK; Park, SJ; Yang, EJ | 1 |
2 review(s) available for 8-hydroxy-2-(di-n-propylamino)tetralin and sb 269970
| Article | Year |
|---|---|
Higher-end serotonin receptors: 5-HT(5), 5-HT(6), and 5-HT(7).
Topics: Animals; Humans; Ligands; Receptors, Serotonin; Serotonin Agents; Serotonin Antagonists; Serotonin Receptor Agonists | 2003 |
Structure-activity relationships of serotonin 5-HT
Topics: Animals; Humans; Ligands; Receptors, Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Structure-Activity Relationship | 2019 |
30 other study(ies) available for 8-hydroxy-2-(di-n-propylamino)tetralin and sb 269970
| Article | Year |
|---|---|
Structure-activity relationship study on N-(1,2,3,4-tetrahydronaphthalen-1-yl)-4-aryl-1-piperazinehexanamides, a class of 5-HT7 receptor agents. 2.
Topics: Amides; Animals; Cell Line; Guinea Pigs; Humans; Ileum; Male; Muscle Contraction; Muscle, Smooth; Piperazines; Radioligand Assay; Rats; Rats, Wistar; Receptors, Serotonin; Serotonin Receptor Agonists; Structure-Activity Relationship; Tetrahydronaphthalenes | 2007 |
Structural modifications of N-(1,2,3,4-tetrahydronaphthalen-1-yl)-4-aryl-1-piperazinehexanamides: influence on lipophilicity and 5-HT7 receptor activity. Part III.
Topics: Animals; Blood-Brain Barrier; Brain; Mice; Molecular Structure; Piperazines; Receptors, Serotonin | 2008 |
Novel arylsulfonamide derivatives with 5-HT₆/5-HT₇ receptor antagonism targeting behavioral and psychological symptoms of dementia.
Topics: Animals; Antidepressive Agents; Antipsychotic Agents; Avoidance Learning; Benzoxazoles; Catalepsy; CHO Cells; Cricetulus; Dementia; Dopamine D2 Receptor Antagonists; HEK293 Cells; Humans; Male; Models, Molecular; Motor Activity; Radioligand Assay; Rats, Wistar; Receptors, Serotonin; Serotonin Antagonists; Structure-Activity Relationship; Sulfonamides | 2014 |
Synthesis and binding properties of new long-chain 4-substituted piperazine derivatives as 5-HT₁A and 5-HT₇ receptor ligands.
Topics: Binding Sites; Dose-Response Relationship, Drug; Humans; Ligands; Molecular Structure; Piperazine; Piperazines; Pyrimidines; Quinazolines; Receptor, Serotonin, 5-HT1A; Receptors, Serotonin; Structure-Activity Relationship | 2015 |
Design and synthesis of new homo and hetero bis-piperazinyl-1-propanone derivatives as 5-HT7R selective ligands over 5-HT1AR.
Topics: Drug Design; Humans; Kinetics; Ligands; Piperazine; Piperazines; Propane; Protein Binding; Receptors, Serotonin; Serotonin Antagonists; Structure-Activity Relationship | 2016 |
New N- and O-arylpiperazinylalkyl pyrimidines and 2-methylquinazolines derivatives as 5-HT
Topics: Dose-Response Relationship, Drug; HEK293 Cells; Humans; Ligands; Models, Molecular; Molecular Structure; Pyrimidines; Quinazolines; Receptor, Serotonin, 5-HT1A; Receptors, Serotonin; Structure-Activity Relationship | 2017 |
[1]Benzothieno[3,2-d]pyrimidine derivatives as ligands for the serotonergic 5-HT
Topics: Dose-Response Relationship, Drug; Humans; Ligands; Models, Molecular; Molecular Structure; Pyrimidines; Receptors, Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Structure-Activity Relationship; Thiophenes | 2019 |
The effect of SB-269970, a 5-HT(7) receptor antagonist, on 5-HT release from serotonergic terminals and cell bodies.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Brain; Cerebral Cortex; Dose-Response Relationship, Drug; Guinea Pigs; In Vitro Techniques; Male; Mediodorsal Thalamic Nucleus; Phenols; Piperidones; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Spiro Compounds; Sulfonamides; Tritium | 2001 |
No involvement of 5-HT(7) or 5-HT(1D) receptors in the (R)-8-OH-DPAT-induced depression of the monosynaptic reflex in spinalized rats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Clozapine; Decerebrate State; Dose-Response Relationship, Drug; Ergolines; Indoles; Male; Methiothepin; Oxadiazoles; Phenols; Piperazines; Pyridines; Rats; Receptor, Serotonin, 5-HT1D; Receptors, Serotonin; Reflex, Monosynaptic; Serotonin Antagonists; Serotonin Receptor Agonists; Sulfonamides; Time Factors | 2001 |
Reconsideration of 5-hydroxytryptamine (5-HT)(7) receptor distribution using [(3)H]5-carboxamidotryptamine and [(3)H]8-hydroxy-2-(di-n-propylamino)tetraline: analysis in brain of 5-HT(1A) knockout and 5-HT(1A/1B) double-knockout mice.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Autoradiography; Brain; Brain Chemistry; Mice; Mice, Knockout; Phenols; Radioligand Assay; Receptor, Serotonin, 5-HT1B; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Sulfonamides | 2002 |
Differential regulation of corticosteroid receptors by monoamine neurotransmitters and antidepressant drugs in primary hippocampal culture.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic beta-Antagonists; Amitriptyline; Animals; Animals, Newborn; Antidepressive Agents; Biogenic Monoamines; Blotting, Western; Carrier Proteins; Culture Techniques; DNA Primers; DNA, Complementary; Drug Interactions; Female; Fluoxetine; Gene Expression Regulation; Hippocampus; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Phenols; Piperazines; Pregnancy; Propranolol; Pyridines; Rats; Rats, Wistar; Receptors, Adrenergic; Receptors, Serotonin; Receptors, Steroid; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Selective Serotonin Reuptake Inhibitors; Serotonin Plasma Membrane Transport Proteins; Serotonin Receptor Agonists; Sulfonamides | 2003 |
8-OH-DPAT acts on both 5-HT1A and 5-HT7 receptors to induce hypothermia in rodents.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Body Temperature; Body Temperature Regulation; Female; Hypothermia; Imidazoles; Indoles; Mice; Phenols; Piperazines; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1A; Receptors, Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Sulfonamides; Telemetry | 2004 |
Aging and SB-269970-A, a selective 5-HT7 receptor antagonist, attenuate circadian phase advances induced by microinjections of serotonergic drugs in the hamster dorsal raphe nucleus.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Age Factors; Analysis of Variance; Animals; Circadian Rhythm; Cricetinae; Dose-Response Relationship, Drug; Drug Interactions; Male; Mesocricetus; Microinjections; Phenols; Raphe Nuclei; Serotonin; Serotonin Agents; Serotonin Antagonists; Sulfonamides | 2004 |
5-HT7 receptor subtype as a mediator of the serotonergic regulation of luteinizing hormone release in the zona incerta.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Female; Luteinizing Hormone; Male; Ovariectomy; Phenols; Piperazines; Rats; Rats, Wistar; Receptors, Serotonin; Ritanserin; Serotonin; Serotonin 5-HT1 Receptor Antagonists; Serotonin 5-HT2 Receptor Antagonists; Serotonin Antagonists; Serotonin Receptor Agonists; Subthalamus; Sulfonamides | 2004 |
Activation of 5-HT1A and 5-HT7 receptors in the parafascicular nucleus suppresses the affective reaction of rats to noxious stimulation.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Affect; Analysis of Variance; Animals; Behavior, Animal; Dopamine Antagonists; Dose-Response Relationship, Drug; Drug Interactions; Functional Laterality; Intralaminar Thalamic Nuclei; Male; Medulla Oblongata; Neural Inhibition; Pain; Pain Measurement; Pain Threshold; Phenols; Physical Stimulation; Piperazines; Prosencephalon; Pyridines; Raclopride; Rats; Rats, Long-Evans; Receptor, Serotonin, 5-HT1A; Receptors, Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Spinal Cord; Sulfonamides; Vocalization, Animal | 2005 |
Serotonin 5-HT7 receptors coupled to induction of interleukin-6 in human microglial MC-3 cells.
Topics: 5-Methoxytryptamine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Blotting, Northern; Blotting, Western; Cell Line; Cyclic AMP; Dose-Response Relationship, Drug; Drug Interactions; Gene Expression Regulation; Humans; Interleukin-6; Microglia; Phenols; Receptors, Serotonin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Serotonin; Serotonin Agents; Serotonin Antagonists; Sulfonamides; Transfection | 2005 |
Investigation of mechanisms mediating 8-OH-DPAT-induced impairment of spatial memory: involvement of 5-HT1A receptors in the dorsal hippocampus in rats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic alpha-Antagonists; Analysis of Variance; Animals; Behavior, Animal; Dose-Response Relationship, Drug; Drug Administration Routes; Drug Interactions; Hippocampus; Male; Maze Learning; Memory Disorders; Microinjections; Phenols; Piperazines; Prazosin; Pyridines; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT1A; Serotonin Antagonists; Sulfonamides | 2006 |
Zimelidine decreases seizure susceptibility in stressed mice.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Anticonvulsants; Behavior, Animal; Convulsants; Ketanserin; Male; Mianserin; Mice; Mice, Inbred CBA; Phenols; Picrotoxin; Piperazines; Pyridines; Seizures; Selective Serotonin Reuptake Inhibitors; Serotonin Antagonists; Serotonin Receptor Agonists; Stress, Psychological; Sulfonamides; Swimming; Zimeldine | 2006 |
Effects of the 5-HT7 receptor antagonist SB-269970 on rat hormonal and temperature responses to the 5-HT1A/7 receptor agonist 8-OH-DPAT.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Body Temperature; Body Temperature Regulation; Corticosterone; Male; Phenols; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1A; Receptors, Serotonin; Serotonin 5-HT1 Receptor Agonists; Serotonin Antagonists; Sulfonamides | 2006 |
Involvement of 5-hydroxytryptamine1A receptors in Delta9-tetrahydrocannabinol-induced catalepsy-like immobilization in mice.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Buspirone; Catalepsy; Dose-Response Relationship, Drug; Dronabinol; Hallucinogens; Male; Mice; Motor Activity; Phenols; Piperazines; Postural Balance; Pyridines; Receptor, Serotonin, 5-HT1A; Serotonin Antagonists; Serotonin Receptor Agonists; Sulfonamides | 2006 |
The effect of the 5-HT1A receptor agonist, 8-OH-DPAT, on motion-induced emesis in Suncus murinus.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Female; Male; Methysergide; Motion; Ondansetron; Phenols; Serotonin 5-HT1 Receptor Agonists; Serotonin 5-HT1 Receptor Antagonists; Serotonin Receptor Agonists; Shrews; Sulfonamides; Vomiting | 2006 |
Attenuating effects of prior oestradiol benzoate priming on 5-HT-mediated lordosis behavior in rats are dose-dependent.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Brain; Dopamine Antagonists; Dose-Response Relationship, Drug; Estradiol; Female; Male; Ovariectomy; Phenols; Piperazines; Posture; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT1A; Receptors, Serotonin; Reflex; Serotonin; Serotonin Receptor Agonists; Sexual Behavior, Animal; Sulfonamides | 2007 |
Delta(9)-tetrahydrocannabinol prolongs the immobility time in the mouse forced swim test: involvement of cannabinoid CB(1) receptor and serotonergic system.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Behavior, Animal; Brain; Citalopram; Dose-Response Relationship, Drug; Dronabinol; Injections, Intraperitoneal; Male; Mice; Motor Activity; Phenols; Piperazines; Piperidines; Psychotropic Drugs; Pyrazoles; Pyridines; Receptor, Cannabinoid, CB1; Receptor, Serotonin, 5-HT1A; Receptors, Serotonin; Rimonabant; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Succinimides; Sulfonamides; Swimming | 2008 |
Neurochemical, behavioral, and physiological effects of pharmacologically enhanced serotonin levels in serotonin transporter (SERT)-deficient mice.
Topics: 5-Hydroxytryptophan; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Brain; Brain Chemistry; Catecholamines; Clorgyline; Dopamine Uptake Inhibitors; Drug Synergism; Drug Therapy, Combination; Female; Hydroxyindoleacetic Acid; Hypothermia; Male; Mice; Mice, Knockout; Monoamine Oxidase Inhibitors; Phenols; Piperazines; Pyridines; Serotonin; Serotonin 5-HT1 Receptor Antagonists; Serotonin Plasma Membrane Transport Proteins; Serotonin Receptor Agonists; Serotonin Syndrome; Sulfonamides; Tranylcypromine | 2008 |
Ex vivo study of 5-HT(1A) and 5-HT(7) receptor agonists and antagonists on cAMP accumulation during memory formation and amnesia.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amnesia; Animals; Behavior, Animal; Cholinergic Antagonists; Cyclic AMP; Dizocilpine Maleate; Enzyme-Linked Immunosorbent Assay; Excitatory Amino Acid Antagonists; Hippocampus; Learning; Male; Memory; Phenols; Piperazines; Pyrazoles; Pyridines; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT1A; Receptors, Serotonin; Scopolamine; Serotonin Antagonists; Serotonin Receptor Agonists; Sulfonamides; Tetrahydronaphthalenes | 2008 |
Memory time-course: mRNA 5-HT1A and 5-HT7 receptors.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Conditioning, Classical; Hippocampus; Male; Memory; Phenols; Piperazines; Prefrontal Cortex; Pyrazoles; Pyridines; Raphe Nuclei; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT1A; Receptors, Serotonin; RNA, Messenger; Serotonin 5-HT1 Receptor Agonists; Serotonin 5-HT1 Receptor Antagonists; Serotonin Antagonists; Serotonin Receptor Agonists; Sulfonamides; Tetrahydronaphthalenes; Time Factors | 2009 |
Serotonin targets inhibitory synapses to induce modulation of network functions.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antibodies, Monoclonal; Brain Stem; Buspirone; Cats; DNA Primers; Efferent Pathways; Immunohistochemistry; Membrane Potentials; Nerve Net; Periodicity; Phenols; Piperazines; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Respiratory Mechanics; Reverse Transcriptase Polymerase Chain Reaction; Serotonin; Serotonin Receptor Agonists; Sulfonamides; Synapses | 2009 |
Elucidating the role of 5-HT(1A) and 5-HT(7) receptors on 8-OH-DPAT-induced behavioral recovery after experimental traumatic brain injury.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Behavior, Animal; Brain Injuries; Male; Maze Learning; Motor Activity; Phenols; Piperazines; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1A; Receptors, Serotonin; Recovery of Function; Serotonin Receptor Agonists; Sulfonamides | 2012 |
Serotonin 5-HT(7) receptor blockade reverses behavioral abnormalities in PACAP-deficient mice and receptor activation promotes neurite extension in primary embryonic hippocampal neurons: therapeutic implications for psychiatric disorders.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antipsychotic Agents; Cell Count; Cells, Cultured; Disease Models, Animal; Drug Evaluation, Preclinical; Exploratory Behavior; Freezing Reaction, Cataleptic; Hippocampus; Hyperkinesis; Maze Learning; Mice; Mice, Inbred ICR; Mice, Knockout; Mice, Neurologic Mutants; Nerve Tissue Proteins; Neurites; Phenols; Physical Endurance; Pituitary Adenylate Cyclase-Activating Polypeptide; Pyrazoles; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Sulfonamides; Tetrahydronaphthalenes | 2012 |
Functional expression of 5-HT⁷ receptor on the substantia gelatinosa neurons of the trigeminal subnucleus caudalis in mice.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Action Potentials; Age Factors; Animals; Animals, Newborn; Drug Interactions; Gene Expression Regulation, Developmental; Mice; Neurons; Phenols; Piperazines; Pyridines; Receptors, Serotonin; RNA, Messenger; Serotonin Antagonists; Serotonin Receptor Agonists; Substantia Gelatinosa; Sulfonamides; Trigeminal Nuclei | 2014 |