8-hydroxy-2-(di-n-propylamino)tetralin and robalzotan

8-hydroxy-2-(di-n-propylamino)tetralin has been researched along with robalzotan in 9 studies

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's5 (55.56)18.2507
2000's2 (22.22)29.6817
2010's2 (22.22)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Eriksson, H; Hu, PS; Jackson, DM; Jerning, E; Johansson, L; Kelder, D; Larsson, LG; Mohell, N; Rényi, L; Ross, SB; Sohn, D; Thorberg, SO; Wallsten, C; Westlind-Danielsson, A1
Larsson, LG; Ross, SB; Stenfors, C1
Jerning, E; Mohell, N; Svantesson, GT1
Ahlenius, S; Hillegaart, V1
Ahlenius, S; Henriksson, I; Magnusson, O; Salmi, P1
Malmberg, A; Strange, PG1
Elvander, E; Lüttgen, M; Madjid, N; Ogren, SO1
Hu, XJ; Kehr, J; Ogren, SO; Osborne, P; Stenfors, C; Wang, FH; Yoshitake, T1
Madjid, N; Modica, MN; Ogren, SO; Pittalà, V; Romeo, G; Salerno, L; Siracusa, MA1

Other Studies

9 other study(ies) available for 8-hydroxy-2-(di-n-propylamino)tetralin and robalzotan

ArticleYear
The pharmacological characterization of a novel selective 5-hydroxytryptamine1A receptor antagonist, NAD-299.
    The Journal of pharmacology and experimental therapeutics, 1997, Volume: 283, Issue:1

    Topics: 5-Hydroxytryptophan; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Avoidance Learning; Benzopyrans; Body Temperature; Corticosterone; Dihydroxyphenylalanine; Male; Piperazines; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Antagonists

1997
Differential regional antagonism of 8-OH-DPAT-induced decrease in serotonin synthesis by two 5-HT1A receptor antagonists.
    European journal of pharmacology, 1998, Apr-10, Volume: 346, Issue:2-3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Benzopyrans; Brain Chemistry; Dose-Response Relationship, Drug; Hippocampus; Hypothalamus; Male; Neostriatum; Piperazines; Prefrontal Cortex; Pyridines; Rats; Rats, Sprague-Dawley; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists

1998
Receptor binding characteristics of [3H]NAD-299, a new selective 5-HT1A receptor antagonist.
    European journal of pharmacology, 1998, Nov-06, Volume: 360, Issue:2-3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Benzopyrans; Binding, Competitive; CHO Cells; Cricetinae; Guanine Nucleotides; Hippocampus; Humans; Ions; Kinetics; Male; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Antagonists; Transfection; Tritium

1998
Facilitation and inhibition of male rat ejaculatory behaviour by the respective 5-HT1A and 5-HT1B receptor agonists 8-OH-DPAT and anpirtoline, as evidenced by use of the corresponding new and selective receptor antagonists NAD-299 and NAS-181.
    British journal of pharmacology, 1998, Volume: 125, Issue:8

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic beta-Antagonists; Animals; Benzopyrans; Ejaculation; Female; Male; Morpholines; Pindolol; Piperidines; Propanolamines; Pyridines; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT1B; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Agents; Serotonin Antagonists; Serotonin Receptor Agonists; Sexual Behavior, Animal; Time Factors

1998
In vivo intrinsic efficacy of the 5-HT1A receptor antagonists NAD-299, WAY-100,635 and (S)-(-)-UH-301 at rat brain monoamine receptors.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 1999, Volume: 9, Issue:1-2

    Topics: 5-Hydroxytryptophan; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Benzopyrans; Brain Chemistry; Dihydroxyphenylalanine; Dose-Response Relationship, Drug; Enzyme Inhibitors; Hippocampus; Hydrazines; Male; Neostriatum; Piperazines; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Biogenic Amine; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Antagonists

1999
Site-directed mutations in the third intracellular loop of the serotonin 5-HT(1A) receptor alter G protein coupling from G(i) to G(s) in a ligand-dependent manner.
    Journal of neurochemistry, 2000, Volume: 75, Issue:3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amino Acid Sequence; Benzopyrans; Buspirone; Cell Line; Cell Membrane; Cyclic AMP; GTP-Binding Protein alpha Subunits, Gi-Go; GTP-Binding Protein alpha Subunits, Gs; Humans; Kinetics; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Pertussis Toxin; Protein Structure, Secondary; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Recombinant Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Serotonin; Serotonin Antagonists; Transfection; Virulence Factors, Bordetella

2000
Analysis of the role of 5-HT1A receptors in spatial and aversive learning in the rat.
    Neuropharmacology, 2005, Volume: 48, Issue:6

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Analysis of Variance; Animals; Avoidance Learning; Behavior, Animal; Benzopyrans; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Antagonists; Male; Maze Learning; Muscarinic Antagonists; Piperazines; Pyridines; Rats; Rats, Sprague-Dawley; Reaction Time; Receptor, Serotonin, 5-HT1A; Scopolamine; Serotonin Antagonists; Serotonin Receptor Agonists; Spatial Behavior; Time Factors

2005
The selective 5-HT(1A) receptor antagonist NAD-299 increases acetylcholine release but not extracellular glutamate levels in the frontal cortex and hippocampus of awake rat.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2010, Volume: 20, Issue:7

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Acetylcholine; Animals; Area Under Curve; Benzopyrans; Cholinesterase Inhibitors; Donepezil; Dose-Response Relationship, Drug; Extracellular Fluid; Frontal Lobe; Glutamic Acid; Hippocampus; Indans; Male; Microdialysis; Neostigmine; Piperidines; Rats; Rats, Sprague-Dawley; Serotonin Antagonists; Serotonin Receptor Agonists; Wakefulness

2010
Analysis of mechanisms for memory enhancement using novel and potent 5-HT1A receptor ligands.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2015, Volume: 25, Issue:8

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Avoidance Learning; Benzopyrans; Conditioning, Psychological; Dose-Response Relationship, Drug; Fumarates; Male; Memory; Mice, Inbred C57BL; Molecular Structure; Receptor, Serotonin, 5-HT1A; Serotonin 5-HT1 Receptor Agonists; Serotonin 5-HT1 Receptor Antagonists

2015