8-hydroxy-2-(di-n-propylamino)tetralin and piperidines

8-hydroxy-2-(di-n-propylamino)tetralin has been researched along with piperidines in 99 studies

Research

Studies (99)

TimeframeStudies, this research(%)All Research%
pre-199019 (19.19)18.7374
1990's33 (33.33)18.2507
2000's30 (30.30)29.6817
2010's14 (14.14)24.3611
2020's3 (3.03)2.80

Authors

AuthorsStudies
Bell, J; Whitaker-Azmitia, PM; Zhang, XN1
Delarue, C; Idres, S; Lefebvre, H; Vaudry, H1
Ben-Zeev, A; Lerer, B; Newman, ME1
Bajjou, R; Chaouche-Teyara, K; Dabiré, H; De Nanteuil, G; Fournier, B; Laubie, M; Safar, M; Schmitt, H1
Kidd, EJ; Leysen, JE; Marsden, CA1
Blier, P; Chaput, Y; de Montigny, C1
Bird, ED; Crino, PB; Plager, MD; Vogt, BA1
Borsini, F; D'Aranno, V; Lecci, A; Mancinelli, A; Meli, A; Stasi, MA; Volterra, G1
Bennett, DA; Glaeser, BS; Hutchison, AJ; Liebman, JM; Lovell, RA; Sills, MA; Williams, M; Wood, PL1
Crino, PB; Vogt, BA; Volicer, L; Wiley, RG1
Geyer, MA; Tapson, GS; Wing, LL1
Dreteler, GH; Saxena, PR; Wouters, W1
Carlsson, S; Hoffmann, P; Skarphedinsson, JO; Thorén, P1
Backus, LI; Grahame-Smith, DG; Sharp, T1
Jackson, DA; White, SR1
Ramage, AG1
Arnt, J; Hyttel, J1
Amoroso, S; Annunziato, L; Basile, V; Canzoniero, L; Di Renzo, G; Fatatis, A; Taglialatela, M1
Dugovic, C; Janssen, PA; Leysen, JE; Marrannes, R; Wauquier, A1
Ahlenius, S; Fernandez-Guasti, A; Larsson, K1
Kameyama, T; Kawashima, K; Nabeshima, T1
Ahlenius, S; Hillegaart, V; Wijkström, A1
Beck, SG; Clarke, WP; Goldfarb, J1
Engel, G; Hoyer, D; Kalkman, HO1
Hibert, M; Middlemiss, DN1
Allen, GS; Huang, S; Peroutka, SJ1
Glennon, RA1
Gudelsky, GA; Koenig, JI; Meltzer, HY1
Dugovic, C; Wauquier, A1
Bockaert, J; Kemp, DE; Sebben, M; Weiss, S1
Baldessarini, RJ; Campbell, A; Froimowitz, M; Gao, YG; Neumeyer, JL1
Carlsson, M; Clark, D; Eriksson, E; Nilsson, C; Svensson, K1
Baldessarini, RJ; Froimowitz, M; Neumeyer, JL1
Ahlenius, S; Larsson, K1
Piercey, M; Roberts, DC; Smith, A1
Czyrak, A; Frankiewicz, T; Maj, J; Rogóz, Z; Skuza, G1
Conway, PC; Corbett, R; Dunn, RW; Hartman, H; Helsley, GC; Kerman, LL; Strupczewski, JT; Woods, AT1
Hyttel, J; Sánchez, C1
Frölich, D; Göthert, M; Likungu, J; Molderings, GJ1
Andrews, P; Matsuki, N; Saito, H; Torii, Y1
Chen, Y; Matsuki, N; Saito, H1
Audinot-Bouchez, V; Chaput, C; Conte, C; Lavielle, G; Lochon, S; Millan, MJ; Newman-Tancredi, A; Verrièle, L1
Assié, MB; Kleven, MS; Koek, W1
O'Neill, MF; Parameswaran, T1
Cagnotto, A; Crespi, D; Gariboldi, M; Mancini, L; Manzoni, C; Mennini, T; Presti, ML; Vezzani, A1
Cook, DF; Wirtshafter, D1
Ashby, CR; Katsumori, H; Minabe, Y; Watanabe, K1
Ahlenius, S; Hillegaart, V1
Timineri, D; Winter, JC1
Piercey, MF; Ray, CA; Walker, EL1
Dupuis, DS; Hall, H; Pauwels, PJ; Radu, D1
Dekeyne, A; Girardon, S; Millan, MJ1
Ichikawa, J; Meltzer, HY1
Dulawa, SC; Geyer, MA; Gross, C; Hen, R; Stark, KL1
Branchek, TA; Calligaro, DO; Czachura, JF; Dreshfield-Ahmad, LJ; Evans, DC; Hemrick-Luecke, SK; Kallman, MJ; Kendrick, WT; Leander, JD; Nelson, DL; Overshiner, CD; Rasmussen, K; Wainscott, DB; Wolff, MC; Wong, DT; Xu, YC; Zgombick, JM1
Andrews, PL; Hagiwara, H; Kakaimoto, S; Matsuki, N; Okada, F; Toyoda, M; Woods, AJ1
Ahlenius, S; Kaur, P1
Conway, MW; O'Neill, MF1
Fu, D; Javitch, JA; Lin, H; Strange, PG; Wilson, J1
Assié, MB; Colpaert, FC; Cosi, C; Koek, W; Patoiseau, JF; Pauwels, PJ; Vacher, B1
Battaglia, G; D'Souza, D; Garcia, F; Muma, NA; Raap, DK; Van de Kar, LD; Zhang, Y1
Blier, P; Szabo, ST1
Davies, CH; Gill, CH; Hagan, JJ; Soffin, EM1
Dai, J; Ichikawa, J; Meltzer, HY1
Gobert, A; Lejeune, F; Millan, MJ1
Awe, SO; Harris, LC; LeDay, AM; Ohia, SE; Opere, CA; Sharif, NA1
Nagao, Y; Ogawa, S; Sano, S; Takehisa, T; Yokoyama, K1
Chudasama, Y; Dalley, JW; Glennon, JC; Robbins, TW; Theobald, DE; Winstanley, CA1
Aguado, A; Benjamin, D; Di Poce, J; Janes, A; Pohorecky, L; Tomie, A1
Baker, LE; Meltzer, HY; Prus, AJ1
Battaglia, G; Carrasco, GA; D'Souza, DN; Damjanoska, KJ; Dudas, B; Garcia, F; Gray, TS; Muma, NA; Sullivan Hanley, NR; Van de Kar, LD; Zainelli, GM; Zhang, Y1
Grandoso, L; Pineda, J; Torrecilla, M; Ugedo, L1
Balducci, C; Baviera, M; Carli, M; Invernizzi, RW1
Fox, MA; Gallagher, PS; Jensen, CL; Murphy, DL1
Eckler, JR; Rabin, RA; Reissig, CJ; Rice, KC; Winter, JC1
Chidori, S; Egashira, N; Fujiwara, M; Hasebe, N; Higashihara, F; Iwasaki, K; Koushi, E; Matsuda, T; Mishima, K; Nishimura, R; Oishi, R1
Abe, M; Egashira, N; Fujiwara, M; Iwasaki, K; Matsushita, M; Mishima, K; Nishimura, R; Oishi, R; Okuno, R1
Assié, MB; Bruins Slot, L; Buritova, J; Colpaert, FC; Cosi, C; Cussac, D; Heusler, P; Lauressergues, E; Martel, JC; Newman-Tancredi, A; Vacher, B1
Cools, AR; Groot Kormelink, T; Steenhof, M; Veenvliet, JV; Verheij, MM1
Dutschmann, M; Manzke, T; Paton, JF; Pickering, AE; Richter, DW; Simms, AE; Waki, H1
Chen, L; Li, X; Salinas, GD1
Jordan, D; Oskutyte, D; Ramage, AG1
France, CP; Koek, W; Li, JX; Rice, KC1
Hu, XJ; Kehr, J; Ogren, SO; Osborne, P; Stenfors, C; Wang, FH; Yoshitake, T1
Auclair, AL; Bardin, L; Colpaert, FC; Depoortère, R; Newman-Tancredi, A; Vacher, B1
Che, CT; Huang, Z; Ip, SP; Mao, QQ; Xian, YF1
Haji, A; Kimura, S; Ohi, Y1
Higuchi, M; Ishihara, H; Maeda, J; Nakatani, Y; Sakai, M; Suhara, T; Suzuki, M; Takenaka, O; Tokunaga, M; Yoshinaga, T; Zhang, MR1
Bastian, G; Bourgoin, S; Hamon, M; Kayser, V; Michot, B1
Gehlert, DR; Shaw, J1
Guimarães, FS; Joca, SR; Sartim, AG1
McMahon, LR1
Lucot, JB1
Browne, CJ; Fletcher, PJ; Higgins, GA; Soko, AD; Zeeb, FD1
Cruz-Martínez, AM; Escartín-Pérez, RE; Florán-Garduño, B; López-Alonso, VE; Mancilla-Díaz, JM; Tejas-Juárez, JG1
Alemany-González, M; Chanovas, J; Delgado-Sallent, C; Gener, T; Nebot, P; Puig, MV; Tauste Campo, A1
Cardoso, AR; Castro, NG; Hammes, CSO; Macena, MV; Marques, AM; Neves, GA; Pinheiro, FML1
Broadbear, JH; Depoortere, RY; Newman-Tancredi, A; Ralph, D; Tunstall, BJ; Vacy, K1
Depoortere, R; Jastrzębska-Więsek, M; Kołaczkowski, M; Newman-Tancredi, A; Varney, MA; Wesołowska, A1

Other Studies

99 other study(ies) available for 8-hydroxy-2-(di-n-propylamino)tetralin and piperidines

ArticleYear
5-HT3 receptor-active drugs alter development of spinal serotonergic innervation: lack of effect of other serotonergic agents.
    Brain research, 1992, Feb-07, Volume: 571, Issue:2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aging; Animals; Biguanides; Female; Fenfluramine; Hypoglycemic Agents; Maternal-Fetal Exchange; Neurons; Pain; Paroxetine; Piperazines; Piperidines; Pregnancy; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Spinal Cord; Tetrahydronaphthalenes; Tropanes

1992
Benzamide derivatives provide evidence for the involvement of a 5-HT4 receptor type in the mechanism of action of serotonin in frog adrenocortical cells.
    Brain research. Molecular brain research, 1991, Volume: 10, Issue:3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenal Cortex; Adrenal Cortex Hormones; Aldosterone; Animals; Benzamides; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cisapride; Corticosterone; In Vitro Techniques; Kinetics; Methysergide; Piperidines; Rana ridibunda; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Tetrahydronaphthalenes

1991
Chloroamphetamine did not prevent the effects of chronic antidepressants on 5-hydroxytryptamine inhibition of forskolin-stimulated adenylate cyclase in rat hippocampus.
    European journal of pharmacology, 1991, Jul-12, Volume: 207, Issue:3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Antidepressive Agents; Binding Sites; Cerebral Cortex; Chlorides; Colforsin; Hippocampus; Imipramine; Lithium; Lithium Chloride; Male; p-Chloroamphetamine; Paroxetine; Piperidines; Rats; Serotonin; Synapses; Tetrahydronaphthalenes

1991
S14063: a new potent 5-HT1A receptor antagonist devoid of beta-adrenoceptor blocking properties.
    European journal of pharmacology, 1991, Oct-15, Volume: 203, Issue:2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic beta-Antagonists; Animals; Benzothiazoles; Blood Pressure; Heart Rate; Male; Piperidines; Rats; Rats, Inbred Strains; Serotonin Antagonists; Tetrahydronaphthalenes; Thiazoles

1991
Chronic 5-HT2 receptor antagonist treatment alters 5-HT1A autoregulatory control of 5-HT release in rat brain in vivo.
    Journal of neuroscience methods, 1990, Volume: 34, Issue:1-3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Brain Chemistry; Cerebral Cortex; Chromatography, High Pressure Liquid; Hydroxyindoleacetic Acid; Piperidines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Ritanserin; Serotonin Antagonists; Tetrahydronaphthalenes

1990
Presynaptic and postsynaptic modifications of the serotonin system by long-term administration of antidepressant treatments. An in vivo electrophysiologic study in the rat.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 1991, Volume: 5, Issue:4

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antidepressive Agents; Electric Stimulation; Electrophysiology; Hippocampus; Imipramine; Male; Neurons; Paroxetine; Piperidines; Pyramidal Tracts; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Synapses; Tetrahydronaphthalenes

1991
Laminar distributions of muscarinic acetylcholine, serotonin, GABA and opioid receptors in human posterior cingulate cortex.
    Neuroscience, 1990, Volume: 36, Issue:1

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aged; Autoradiography; Cerebral Cortex; Dynorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Female; Humans; Iodocyanopindolol; Ketanserin; Male; Middle Aged; Oxotremorine; Paroxetine; Pindolol; Piperidines; Pirenzepine; Receptors, Cell Surface; Receptors, Cholinergic; Receptors, GABA-A; Receptors, Muscarinic; Receptors, Opioid; Receptors, Serotonin; Serotonin; Tetrahydronaphthalenes

1990
Effect of serotoninergic drugs on stress-induced hyperthermia (SIH) in mice.
    Journal of neural transmission. General section, 1990, Volume: 82, Issue:3

    Topics: 5,7-Dihydroxytryptamine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Anti-Anxiety Agents; Body Temperature Regulation; Buspirone; Diazepam; Ergolines; Fenclonine; Fever; Flumazenil; Imidazoles; Male; Mice; Ondansetron; Piperazines; Piperidines; Ritanserin; Serotonin; Serotonin Antagonists; Stress, Psychological; Tetrahydronaphthalenes

1990
CGS 18102A, a benzopyranopyridine anxiolytic with 5-HT1 agonist and 5-HT2 antagonist properties.
    Progress in clinical and biological research, 1990, Volume: 361

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Anti-Anxiety Agents; Benzopyrans; Binding, Competitive; Cerebral Cortex; Ketanserin; Kinetics; Piperidines; Rats; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Tetrahydronaphthalenes

1990
Cellular localization of serotonin 1A, 1B and uptake sites in cingulate cortex of the rat.
    The Journal of pharmacology and experimental therapeutics, 1990, Volume: 252, Issue:2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Cerebral Cortex; Immunotoxins; Iodocyanopindolol; Male; Paroxetine; Pindolol; Piperidines; Rats; Receptors, Serotonin; Serotonin; Tetrahydronaphthalenes

1990
5HT-2 mediation of acute behavioral effects of hallucinogens in rats.
    Psychopharmacology, 1990, Volume: 100, Issue:3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Behavior, Animal; DOM 2,5-Dimethoxy-4-Methylamphetamine; Dose-Response Relationship, Drug; Hallucinogens; Ketanserin; Male; Mescaline; Piperidines; Quipazine; Rats; Rats, Inbred Strains; Ritanserin; Serotonin; Tetrahydronaphthalenes

1990
Comparison of the cardiovascular effects of the 5-HT1A receptor agonist flesinoxan with that of 8-OH-DPAT in the rat.
    European journal of pharmacology, 1990, May-16, Volume: 180, Issue:2-3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Anesthesia; Animals; Antihypertensive Agents; Atropine; Blood Pressure; Decerebrate State; Heart Rate; Hemodynamics; Imidazoles; In Vitro Techniques; Male; Naphthalenes; Ondansetron; Piperazines; Piperidines; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Receptors, Serotonin; Ritanserin; Serotonin Antagonists; Tetrahydronaphthalenes

1990
Role of different serotonergic receptors in the long-lasting blood pressure depression following muscle stimulation in the spontaneously hypertensive rat.
    Acta physiologica Scandinavica, 1990, Volume: 139, Issue:2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Blood Pressure; Electric Stimulation; Heart Rate; Indoles; Male; Methiothepin; Muscles; Piperidines; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Receptors, Serotonin; Ritanserin; Serotonin Antagonists; Tetrahydronaphthalenes; Time Factors; Tropisetron

1990
Behavioural evidence for a functional interaction between central 5-HT2 and 5-HT1A receptors.
    British journal of pharmacology, 1990, Volume: 100, Issue:4

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Apomorphine; Behavior, Animal; Central Nervous System; Dose-Response Relationship, Drug; Haloperidol; Ketanserin; Male; Methoxydimethyltryptamines; Piperidines; Prazosin; Pyrimidines; Quinolines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Ritanserin; Serotonin; Stereotyped Behavior; Tetrahydronaphthalenes

1990
Receptor subtypes mediating facilitation by serotonin of excitability of spinal motoneurons.
    Neuropharmacology, 1990, Volume: 29, Issue:9

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; In Vitro Techniques; Injections, Intravenous; Iontophoresis; Ketanserin; Male; Methysergide; Microelectrodes; Motor Neurons; Piperidines; Prazosin; Quipazine; Rats; Rats, Inbred Strains; Receptors, Serotonin; Ritanserin; Serotonin; Serotonin Antagonists; Spinal Cord; Tetrahydronaphthalenes

1990
Are drugs that act both on serotonin receptors and alpha 1-adrenoceptors more potent hypotensive agents than those that act only on alpha 1-adrenoceptors?
    Journal of cardiovascular pharmacology, 1988, Volume: 11 Suppl 1

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Blood Pressure; Cats; Cinanserin; Ergolines; Ketanserin; Male; Metergoline; Piperidines; Prazosin; Receptors, Adrenergic, alpha; Receptors, Serotonin; Ritanserin; Serotonin Antagonists; Sympathetic Nervous System; Tetrahydronaphthalenes

1988
Facilitation of 8-OHDPAT-induced forepaw treading of rats by the 5-HT2 agonist DOI.
    European journal of pharmacology, 1989, Feb-14, Volume: 161, Issue:1

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Alprenolol; Amphetamines; Animals; Behavior, Animal; Cerebral Cortex; Injections, Subcutaneous; Ketanserin; Male; Naphthalenes; Piperidines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Ritanserin; Tetrahydronaphthalenes

1989
Pharmacological characterization of serotonin receptors involved in the control of prolactin secretion.
    European journal of pharmacology, 1989, Mar-21, Volume: 162, Issue:2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Fenfluramine; Indoles; Male; Piperidines; Prolactin; Quipazine; Rats; Rats, Inbred Strains; Receptors, Serotonin; Ritanserin; Tetrahydronaphthalenes

1989
Functional role of 5-HT2 receptors in the regulation of sleep and wakefulness in the rat.
    Psychopharmacology, 1989, Volume: 97, Issue:4

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Cinanserin; DOM 2,5-Dimethoxy-4-Methylamphetamine; Dose-Response Relationship, Drug; Indoles; Male; Piperidines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Ritanserin; Sleep; Tetrahydronaphthalenes; Wakefulness

1989
Evidence for the involvement of central 5-HT1A receptors in the mediation of lordosis behavior in the female rat.
    Psychopharmacology, 1989, Volume: 98, Issue:4

    Topics: 5-Hydroxytryptophan; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Betaxolol; Estradiol; Female; Male; Methiothepin; Pindolol; Piperidines; Posture; Propanolamines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Sexual Behavior, Animal; Tetrahydronaphthalenes

1989
Effect of minaprine on cycloheximide-induced amnesia in mice.
    European journal of pharmacology, 1989, Oct-10, Volume: 169, Issue:2-3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amnesia; Animals; Avoidance Learning; Cycloheximide; Drug Interactions; Male; Mice; p-Chloroamphetamine; Physostigmine; Piperidines; Pyridazines; Ritanserin; Scopolamine; Tetrahydronaphthalenes

1989
Evidence for selective inhibition of limbic forebrain dopamine synthesis by 8-OH-DPAT in the rat.
    Naunyn-Schmiedeberg's archives of pharmacology, 1989, Volume: 339, Issue:5

    Topics: 5-Hydroxytryptophan; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Corpus Striatum; Depression, Chemical; Dihydroxyphenylalanine; Dopamine; Ergolines; Hydrazines; Limbic System; Male; Naphthalenes; Piperidines; Quinpirole; Rats; Rats, Inbred Strains; Reserpine; Serotonin; Tetrahydronaphthalenes; Tryptophan Hydroxylase; Tyrosine 3-Monooxygenase

1989
Spiperone differentiates multiple 5-hydroxytryptamine responses in rat hippocampal slices in vitro.
    European journal of pharmacology, 1985, Oct-08, Volume: 116, Issue:1-2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Butyrophenones; Hippocampus; In Vitro Techniques; Ketanserin; Piperidines; Rats; Receptors, Serotonin; Spiperone; Tetrahydronaphthalenes

1985
Molecular pharmacology of 5-HT1 and 5-HT2 recognition sites in rat and pig brain membranes: radioligand binding studies with [3H]5-HT, [3H]8-OH-DPAT, (-)[125I]iodocyanopindolol, [3H]mesulergine and [3H]ketanserin.
    European journal of pharmacology, 1985, Nov-26, Volume: 118, Issue:1-2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Brain Chemistry; Choroid Plexus; Ergolines; In Vitro Techniques; Iodocyanopindolol; Ketanserin; Male; Membranes; Pindolol; Piperidines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin; Swine; Tetrahydronaphthalenes

1985
Stereoselective blockade at the 5-HT autoreceptor and inhibition of radioligand binding to central 5-HT recognition sites by the optical isomers of methiothepin.
    Neuropharmacology, 1986, Volume: 25, Issue:1

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Dibenzothiepins; Frontal Lobe; In Vitro Techniques; Ketanserin; Male; Methiothepin; Piperidines; Rats; Receptors, Serotonin; Serotonin; Stereoisomerism; Tetrahydronaphthalenes

1986
Canine basilar artery contractions mediated by 5-hydroxytryptamine1A receptors.
    The Journal of pharmacology and experimental therapeutics, 1986, Volume: 237, Issue:3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Basilar Artery; Dogs; Dose-Response Relationship, Drug; In Vitro Techniques; Kinetics; Lysergic Acid Diethylamide; Piperidines; Rats; Receptors, Serotonin; Serotonin; Spiperone; Tetrahydronaphthalenes; Tritium; Vasoconstriction

1986
Discriminative stimulus properties of the 5-HT1A agonist 8-hydroxy-2-(di-n-propylamino)tetralin (8-OH DPAT).
    Pharmacology, biochemistry, and behavior, 1986, Volume: 25, Issue:1

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Discrimination Learning; DOM 2,5-Dimethoxy-4-Methylamphetamine; Ketanserin; Male; Naphthalenes; Piperazines; Piperidines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Tetrahydronaphthalenes

1986
Thermoregulatory responses to serotonin (5-HT) receptor stimulation in the rat. Evidence for opposing roles of 5-HT2 and 5-HT1A receptors.
    Neuropharmacology, 1986, Volume: 25, Issue:12

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Body Temperature Regulation; Ketanserin; Male; Methoxydimethyltryptamines; Pindolol; Piperidines; Pyrazines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Spiperone; Tetrahydronaphthalenes

1986
5-HT2 receptors could be primarily involved in the regulation of slow-wave sleep in the rat.
    European journal of pharmacology, 1987, May-07, Volume: 137, Issue:1

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; DOM 2,5-Dimethoxy-4-Methylamphetamine; Dose-Response Relationship, Drug; Indoles; Piperidines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Ritanserin; Sleep; Tetrahydronaphthalenes

1987
Serotonin 5-HT1 receptors mediate inhibition of cyclic AMP production in neurons.
    European journal of pharmacology, 1986, Jan-21, Volume: 120, Issue:2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adenylyl Cyclases; Animals; Brain; Cerebral Cortex; Corpus Striatum; Cyclic AMP; Female; Fetus; Indoles; Ketanserin; Metergoline; Mice; Neurons; Piperidines; Pregnancy; Receptors, Serotonin; Tetrahydronaphthalenes; Vasoactive Intestinal Peptide

1986
Neuropharmacology and stereochemistry of dopamine receptor agonist and antagonist enantiomeric pairs.
    Journal of receptor research, 1988, Volume: 8, Issue:1-4

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aporphines; Dopamine; Molecular Conformation; Naphthalenes; Piperidines; Receptors, Dopamine; Stereoisomerism; Structure-Activity Relationship; Tetrahydronaphthalenes

1988
Compounds with selectivity for dopamine autoreceptors: effects on prolactin secretion in male and female rats.
    Clinical neuropharmacology, 1986, Volume: 9 Suppl 4

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Azepines; Female; Male; Phenanthrenes; Piperidines; Prolactin; Rats; Rats, Inbred Strains; Receptors, Dopamine; Tetrahydronaphthalenes

1986
A stereochemical explanation of the dopamine agonist and antagonist activity of stereoisomeric pairs.
    Journal of medicinal chemistry, 1986, Volume: 29, Issue:9

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Apomorphine; Chemical Phenomena; Chemistry; Dopamine; Dopamine Antagonists; Molecular Conformation; Naphthalenes; Piperidines; Receptors, Dopamine; Stereoisomerism; Structure-Activity Relationship; Tetrahydronaphthalenes; Thermodynamics

1986
Failure to antagonize the 8-hydroxy-2-di-n-propylamino)tetralin-induced facilitation of male rat sexual behavior by the administration of 5-HT receptor antagonists.
    European journal of pharmacology, 1984, Apr-06, Volume: 99, Issue:4

    Topics: 5-Hydroxytryptophan; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Female; Male; Metergoline; Methiothepin; Naphthalenes; Piperidines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin Antagonists; Sexual Behavior, Animal; Tetrahydronaphthalenes

1984
Effect of (-)-DS 121 and (+)-UH 232 on cocaine self-administration in rats.
    Psychopharmacology, 1995, Volume: 120, Issue:1

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Cocaine; Conditioning, Operant; Dopamine Antagonists; Dose-Response Relationship, Drug; Male; Nitriles; Piperidines; Rats; Rats, Inbred Strains; Self Administration

1995
Pharmacological action of zotepine and other antipsychotics on central 5-hydroxytryptamine receptor subtypes.
    Arzneimittel-Forschung, 1994, Volume: 44, Issue:2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antipsychotic Agents; Behavior, Animal; Body Temperature; Clozapine; Dibenzothiepins; Exploratory Behavior; Haloperidol; Isoxazoles; Male; Mice; Motor Activity; Piperazines; Piperidines; Rats; Rats, Wistar; Receptors, Serotonin; Risperidone; Serotonin Antagonists; Serotonin Receptor Agonists

1994
Effects of atypical antipsychotic agents on social behavior in rodents.
    Pharmacology, biochemistry, and behavior, 1993, Volume: 45, Issue:1

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antipsychotic Agents; Apomorphine; Benzazepines; Catalepsy; Chlorpromazine; Clozapine; Diazepam; Haloperidol; Isoxazoles; Male; Mice; Mice, Inbred Strains; Piperidines; Raclopride; Radioligand Assay; Rats; Rats, Wistar; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, Serotonin; Risperidone; Salicylamides; Social Behavior

1993
Isolation-induced aggression in mice: effects of 5-hydroxytryptamine uptake inhibitors and involvement of postsynaptic 5-HT1A receptors.
    European journal of pharmacology, 1994, Nov-03, Volume: 264, Issue:3

    Topics: 1-Naphthylamine; 5-Hydroxytryptophan; 8-Hydroxy-2-(di-n-propylamino)tetralin; Aggression; Analysis of Variance; Animals; Behavior, Animal; Brain; Citalopram; Dose-Response Relationship, Drug; Fenclonine; Fluoxetine; Fluvoxamine; Male; Mice; Paroxetine; Penbutolol; Piperidines; Rats; Rats, Wistar; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Selective Serotonin Reuptake Inhibitors; Sertraline; Synaptosomes

1994
Inhibition of noradrenaline release via presynaptic 5-HT1D alpha receptors in human atrium.
    Naunyn-Schmiedeberg's archives of pharmacology, 1996, Volume: 353, Issue:3

    Topics: 5-Methoxytryptamine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic Uptake Inhibitors; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Cisapride; Corticosterone; Desipramine; Heart Atria; Humans; Indoles; Ketanserin; Male; Middle Aged; Norepinephrine; Oxadiazoles; Piperidines; Receptors, Presynaptic; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Sumatriptan; Tritium; Tryptamines

1996
The pharmacology of the emetic response to upper gastrointestinal tract stimulation in Suncus murinus.
    European journal of pharmacology, 1996, Jul-04, Volume: 307, Issue:3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Digestive System Physiological Phenomena; Diterpenes; Granisetron; Male; Morphine; Motion; Neurokinin-1 Receptor Antagonists; Nicotine; Piperidines; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; Serotonin Antagonists; Serotonin Receptor Agonists; Shrews; Vomiting

1996
Ethanol-induced emesis in the house musk shrew, Suncus murinus.
    Life sciences, 1997, Volume: 60, Issue:4-5

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Acetaldehyde; Alcohol Deterrents; Animals; Antiemetics; Baclofen; Benzamides; Bridged Bicyclo Compounds, Heterocyclic; Central Nervous System Depressants; Disulfiram; Dose-Response Relationship, Drug; Ethanol; Female; GABA Antagonists; Indoles; Injections, Intraperitoneal; Injections, Intraventricular; Injections, Subcutaneous; Male; Piperidines; Serotonin Antagonists; Serotonin Receptor Agonists; Shrews; Tiopronin; Tropisetron; Vagotomy; Vomiting

1997
Agonist activity of antimigraine drugs at recombinant human 5-HT1A receptors: potential implications for prophylactic and acute therapy.
    Naunyn-Schmiedeberg's archives of pharmacology, 1997, Volume: 355, Issue:6

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Benzopyrans; Binding, Competitive; Cell Membrane; Cricetinae; Dihydroergotamine; Guanosine 5'-O-(3-Thiotriphosphate); Guinea Pigs; Humans; In Vitro Techniques; Indoles; Lisuride; Methysergide; Migraine Disorders; Piperazines; Piperidines; Pizotyline; Propranolol; Propylamines; Protein Binding; Pyridines; Pyrimidines; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Recombinant Proteins; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Sumatriptan; Tryptamines

1997
Pharmacological characterization of in vivo properties of putative mixed 5-HT1A agonist/5-HT(2A/2C) antagonist anxiolytics. II. Drug discrimination and behavioral observation studies in rats.
    The Journal of pharmacology and experimental therapeutics, 1997, Volume: 282, Issue:2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Anti-Anxiety Agents; Behavior, Animal; Benzopyrans; Discrimination, Psychological; Ketanserin; Lysergic Acid Diethylamide; Male; Nicotinic Acids; Piperazines; Piperidines; Protein Binding; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Ritanserin; Serotonin Antagonists; Serotonin Receptor Agonists

1997
RU24969-induced behavioural syndrome requires activation of both 5HT1A and 5HT1B receptors.
    Psychopharmacology, 1997, Volume: 132, Issue:3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Indoles; Male; Motor Activity; Piperidines; Pyridines; Rats; Receptor, Serotonin, 5-HT1B; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Antagonists; Serotonin Receptor Agonists; Stereotyped Behavior

1997
Lasting increase in serotonin 5-HT1A but not 5-HT4 receptor subtypes in the kindled rat dentate gyrus: dissociation from local presynaptic effects.
    Journal of neurochemistry, 1998, Volume: 70, Issue:2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Cerebral Cortex; Dentate Gyrus; Dioxanes; Electric Stimulation; Functional Laterality; Hippocampus; Iodine Radioisotopes; Kindling, Neurologic; Male; Neurons; Piperazines; Piperidines; Pyridines; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Receptors, Serotonin, 5-HT4; Serotonin; Serotonin Antagonists; Synapses; Tritium

1998
Serotonin-1B agonists induce compartmentally organized striatal Fos expression in rats.
    Neuroreport, 1998, Apr-20, Volume: 9, Issue:6

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aminopyridines; Animals; Corpus Striatum; Immunohistochemistry; Indoles; Male; Nerve Tissue Proteins; Piperazines; Piperidines; Proto-Oncogene Proteins c-fos; Pyridines; Rats; Rats, Sprague-Dawley; Serotonin Antagonists; Serotonin Receptor Agonists

1998
Effect of acute administration of various 5-HT receptor agonists on focal hippocampal seizures in freely moving rats.
    European journal of pharmacology, 1998, Jun-05, Volume: 350, Issue:2-3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Behavior, Animal; Electric Stimulation; Electrodes, Implanted; Electroencephalography; Epilepsy, Complex Partial; Fluoxetine; Hippocampus; Kindling, Neurologic; Male; Piperidines; Rats; Rats, Wistar; Selective Serotonin Reuptake Inhibitors; Serotonin Receptor Agonists

1998
Facilitation and inhibition of male rat ejaculatory behaviour by the respective 5-HT1A and 5-HT1B receptor agonists 8-OH-DPAT and anpirtoline, as evidenced by use of the corresponding new and selective receptor antagonists NAD-299 and NAS-181.
    British journal of pharmacology, 1998, Volume: 125, Issue:8

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic beta-Antagonists; Animals; Benzopyrans; Ejaculation; Female; Male; Morpholines; Pindolol; Piperidines; Propanolamines; Pyridines; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT1B; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Agents; Serotonin Antagonists; Serotonin Receptor Agonists; Sexual Behavior, Animal; Time Factors

1998
The discriminative stimulus properties of EGb 761, an extract of Ginkgo biloba.
    Pharmacology, biochemistry, and behavior, 1999, Volume: 62, Issue:3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Discrimination, Psychological; Dose-Response Relationship, Drug; Flavonoids; Ginkgo biloba; Injections, Intraperitoneal; Male; Piperazines; Piperidines; Plant Extracts; Plants, Medicinal; Pyridines; Rats; Rats, Inbred F344; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Reinforcement Schedule; Serotonin Antagonists; Serotonin Receptor Agonists

1999
The effects of (+)-UH232 and (-)-DS121 on local cerebral glucose utilization in rats.
    Journal of neural transmission (Vienna, Austria : 1996), 1999, Volume: 106, Issue:1

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamine; Animals; Autoradiography; Brain; Central Nervous System Stimulants; Dopamine Antagonists; Drug Combinations; Glucose; Male; Nitriles; Piperidines; Rats; Rats, Sprague-Dawley

1999
Autoradiographic studies of 5-HT1A-receptor-stimulated [35S]GTPgammaS-binding responses in the human and monkey brain.
    The European journal of neuroscience, 1999, Volume: 11, Issue:5

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Autoradiography; Binding, Competitive; Brain Chemistry; Female; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Indoles; Macaca fascicularis; Male; Oxadiazoles; Piperazines; Piperidines; Pyridines; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Antagonists; Serotonin Receptor Agonists; Sulfur Radioisotopes; Tritium; Tryptamines

1999
Discriminative stimulus properties of the novel serotonin (5-HT)2C receptor agonist, RO 60-0175: a pharmacological analysis.
    Neuropharmacology, 1999, Volume: 38, Issue:3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aminopyridines; Animals; Conditioning, Operant; Ethylamines; Fluorobenzenes; Indoles; Male; Mianserin; Piperazines; Piperidines; Pyrazines; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; Reinforcement, Psychology; Serotonin Antagonists; Serotonin Receptor Agonists; Thiophenes

1999
The effect of serotonin(1A) receptor agonism on antipsychotic drug-induced dopamine release in rat striatum and nucleus accumbens.
    Brain research, 2000, Mar-10, Volume: 858, Issue:2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antipsychotic Agents; Clozapine; Corpus Striatum; Dopamine; Fluorobenzenes; Haloperidol; Male; Microdialysis; Nucleus Accumbens; Piperazines; Piperidines; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Risperidone; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Tritium

2000
Knockout mice reveal opposite roles for serotonin 1A and 1B receptors in prepulse inhibition.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2000, Volume: 22, Issue:6

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Brain; Female; Habituation, Psychophysiologic; Indoles; Mice; Mice, Knockout; Neural Inhibition; Piperazines; Piperidines; Pyridines; Receptor, Serotonin, 5-HT1B; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Reflex, Startle; Serotonin Receptor Agonists

2000
The novel 5-Hydroxytryptamine(1A) antagonist LY426965: effects on nicotine withdrawal and interactions with fluoxetine.
    The Journal of pharmacology and experimental therapeutics, 2000, Volume: 294, Issue:2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Acoustic Stimulation; Animals; Body Temperature; Columbidae; Corticosterone; Depression; Discrimination Learning; Drug Interactions; Fluoxetine; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Lip; Male; Microdialysis; Neurons; Nicotine; Piperidines; Posture; Rats; Rats, Long-Evans; Rats, Sprague-Dawley; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Reflex, Startle; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Smoking Cessation; Substance Withdrawal Syndrome; Sulfur Radioisotopes

2000
The emetic and anti-emetic effects of the capsaicin analogue resiniferatoxin in Suncus murinus, the house musk shrew.
    British journal of pharmacology, 2000, Volume: 130, Issue:6

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Abdomen; Animals; Animals, Newborn; Antiemetics; Behavior, Animal; Capsaicin; Cisplatin; Copper Sulfate; Diterpenes; Dose-Response Relationship, Drug; Female; Indoles; Injections, Intraventricular; Male; Medulla Oblongata; Morphine; Motion Sickness; Nicotine; Piperidines; Proto-Oncogene Proteins c-fos; Serotonin Receptor Agonists; Shrews; Tropisetron; Vagotomy; Vomiting

2000
Non-serotonergic potentiation by (-)-pindolol of DOI-induced forward locomotion in rats: possible involvement of beta-adrenoceptors?.
    Journal of neural transmission (Vienna, Austria : 1996), 2000, Volume: 107, Issue:8-9

    Topics: 5-Hydroxytryptophan; 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic beta-Antagonists; Adrenergic Uptake Inhibitors; Animals; Betaxolol; Biogenic Monoamines; Dihydroxyphenylalanine; Drug Synergism; Indophenol; Male; Motor Activity; Pindolol; Piperazines; Piperidines; Propanolamines; Prosencephalon; Pyridines; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT1B; Receptors, Adrenergic, beta; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Reserpine; Serotonin Antagonists; Serotonin Receptor Agonists

2000
Role of 5-HT(1A) and 5-HT(1B) receptors in the mediation of behavior in the forced swim test in mice.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2001, Volume: 24, Issue:4

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antidepressive Agents, Tricyclic; Behavior, Animal; Dose-Response Relationship, Drug; Female; Imipramine; Indoles; Mice; Mice, Inbred Strains; Motor Activity; Oxadiazoles; Piperazines; Piperidines; Pyridines; Reaction Time; Receptor, Serotonin, 5-HT1B; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Antagonists; Serotonin Receptor Agonists; Swimming

2001
Mechanisms of inverse agonism of antipsychotic drugs at the D(2) dopamine receptor: use of a mutant D(2) dopamine receptor that adopts the activated conformation.
    Journal of neurochemistry, 2001, Volume: 77, Issue:2

    Topics: 1-Methyl-3-isobutylxanthine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antipsychotic Agents; Apomorphine; Binding, Competitive; Bromocriptine; Butaclamol; Chlorpromazine; CHO Cells; Clozapine; Colforsin; Cricetinae; Cricetulus; Cyclic AMP; Dopamine Agonists; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Dose-Response Relationship, Drug; GTP-Binding Proteins; Haloperidol; Humans; Macromolecular Substances; Mutagenesis, Site-Directed; Phenethylamines; Piperidines; Protein Binding; Protein Conformation; Radioligand Assay; Receptors, Dopamine D2; Recombinant Fusion Proteins; Sodium; Spiperone; Structure-Activity Relationship; Sulpiride; Transfection; Tyramine

2001
5-HT1A receptor activation and antidepressant-like effects: F 13714 has high efficacy and marked antidepressant potential.
    European journal of pharmacology, 2001, May-25, Volume: 420, Issue:2-3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aminopyridines; Animals; Antidepressive Agents; Binding, Competitive; Buspirone; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Guanosine 5'-O-(3-Thiotriphosphate); HeLa Cells; Humans; Male; Motor Activity; Piperazines; Piperidines; Pyridines; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Antagonists; Serotonin Receptor Agonists; Swimming

2001
Characterization of the functional heterologous desensitization of hypothalamic 5-HT(1A) receptors after 5-HT(2A) receptor activation.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2001, Oct-15, Volume: 21, Issue:20

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenocorticotropic Hormone; Amphetamines; Animals; Binding, Competitive; Dose-Response Relationship, Drug; Fluorobenzenes; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Hypothalamus; Male; Membrane Proteins; Oxytocin; Piperidines; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Antagonists; Serotonin Receptor Agonists

2001
Functional and pharmacological characterization of the modulatory role of serotonin on the firing activity of locus coeruleus norepinephrine neurons.
    Brain research, 2001, Dec-13, Volume: 922, Issue:1

    Topics: 5,7-Dihydroxytryptamine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Antagonists; Amphetamines; Animals; Electric Stimulation; Electrophysiology; Fluorobenzenes; Idazoxan; Locus Coeruleus; Male; Neurons; Norepinephrine; Paroxetine; Patch-Clamp Techniques; Piperazines; Piperidines; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Antagonists

2001
5-HT7 receptors modulate synchronized network activity in rat hippocampus.
    Neuropharmacology, 2002, Volume: 42, Issue:1

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Dioxanes; Extracellular Space; Hippocampus; Male; Membrane Potentials; Microelectrodes; Nerve Net; Piperazines; Piperidines; Potassium Channels, Calcium-Activated; Pyramidal Cells; Pyridines; Rats; Receptors, Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists

2002
5-HT(1A) and 5-HT(2A) receptors minimally contribute to clozapine-induced acetylcholine release in rat medial prefrontal cortex.
    Brain research, 2002, Jun-07, Volume: 939, Issue:1-2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Acetylcholine; Animals; Clozapine; Corpus Striatum; Dopamine Antagonists; Fluorobenzenes; Haloperidol; Indophenol; Male; Microdialysis; Nucleus Accumbens; Piperazines; Piperidines; Prefrontal Cortex; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Antagonists; Serotonin Receptor Agonists; Time Factors

2002
The selective neurokinin (NK)(1) antagonist, GR205,171, stereospecifically enhances mesocortical dopaminergic transmission in the rat: a combined dialysis and electrophysiological study.
    Brain research, 2002, May-10, Volume: 935, Issue:1-2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Action Potentials; Animals; Antiemetics; Apomorphine; Depression; Dopamine; Dopamine Agonists; Dose-Response Relationship, Drug; Extracellular Space; Isomerism; Male; Microdialysis; Neural Pathways; Neurokinin-1 Receptor Antagonists; Piperidines; Prefrontal Cortex; Presynaptic Terminals; Rats; Rats, Wistar; Receptors, Neurokinin-1; Serotonin Receptor Agonists; Synaptic Transmission; Tetrazoles; Up-Regulation; Ventral Tegmental Area

2002
Pharmacology of serotonin receptors modulating electrically-induced [3h]-norepinephrine release from isolated mammalian iris-ciliary bodies.
    Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 2002, Volume: 18, Issue:4

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Biguanides; Cattle; Ciliary Body; Dose-Response Relationship, Drug; Electric Stimulation; Humans; In Vitro Techniques; Iris; Norepinephrine; Piperidines; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Sulfonamides; Tritium; Tropanes

2002
Stereoselective synthesis of tetrasubstituted (Z)-alkenes from aryl alkyl ketones utilizing the Horner-Wadsworth-Emmons reaction.
    Chemical & pharmaceutical bulletin, 2002, Volume: 50, Issue:9

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Alkenes; Catalysis; Cinnamates; Indicators and Reagents; Ketones; Methylation; Piperidines; Stereoisomerism

2002
Intra-prefrontal 8-OH-DPAT and M100907 improve visuospatial attention and decrease impulsivity on the five-choice serial reaction time task in rats.
    Psychopharmacology, 2003, Volume: 167, Issue:3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Attention; Behavior, Animal; Choice Behavior; Dose-Response Relationship, Drug; Drug Administration Routes; Fluorobenzenes; Impulsive Behavior; Male; Piperidines; Prefrontal Cortex; Rats; Reaction Time; Serotonin Agents; Serotonin Antagonists; Spatial Behavior

2003
Effects of autoshaping procedures on 3H-8-OH-DPAT-labeled 5-HT1a binding and 125I-LSD-labeled 5-HT2a binding in rat brain.
    Brain research, 2003, Jun-13, Volume: 975, Issue:1-2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Anti-Anxiety Agents; Autoradiography; Brain Chemistry; Buspirone; Central Nervous System Depressants; Conditioning, Classical; Corticosterone; Ethanol; Iodine Radioisotopes; Lysergic Acid Diethylamide; Male; Piperidines; Rats; Rats, Long-Evans; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Selective Serotonin Reuptake Inhibitors; Serotonin Receptor Agonists; Zimeldine

2003
Discriminative stimulus properties of 1.25 and 5.0 mg/kg doses of clozapine in rats: examination of the role of dopamine, serotonin, and muscarinic receptor mechanisms.
    Pharmacology, biochemistry, and behavior, 2004, Volume: 77, Issue:2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antipsychotic Agents; Butyrophenones; Clozapine; Discrimination, Psychological; Dopamine; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Dose-Response Relationship, Drug; Fluorobenzenes; Generalization, Stimulus; Haloperidol; Male; Muscarinic Antagonists; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Trihexyphenidyl

2004
Desensitization of 5-HT1A receptors by 5-HT2A receptors in neuroendocrine neurons in vivo.
    The Journal of pharmacology and experimental therapeutics, 2004, Volume: 310, Issue:1

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenocorticotropic Hormone; Amphetamines; Animals; Antibody Specificity; Corticotropin-Releasing Hormone; Fluorobenzenes; Microinjections; Neurons; Neurosecretory Systems; Oxytocin; Paraventricular Hypothalamic Nucleus; Piperidines; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1A; Receptor, Serotonin, 5-HT2A; Serotonin Antagonists; Serotonin Receptor Agonists

2004
alpha(2)-Adrenoceptor involvement in the in vitro inhibitory effect of citalopram on a subpopulation of rat locus coeruleus neurons.
    European journal of pharmacology, 2005, Jul-04, Volume: 517, Issue:1-2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Action Potentials; Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Amphetamines; Animals; Bridged Bicyclo Compounds, Heterocyclic; Brimonidine Tartrate; Citalopram; Dose-Response Relationship, Drug; Duloxetine Hydrochloride; Idazoxan; In Vitro Techniques; Locus Coeruleus; Male; Methiothepin; Naloxone; Narcotic Antagonists; Neurons; Norepinephrine; Oxazines; Piperazines; Piperidines; Pyridines; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Receptors, Opioid, mu; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Thiophenes

2005
Dissociable contribution of 5-HT1A and 5-HT2A receptors in the medial prefrontal cortex to different aspects of executive control such as impulsivity and compulsive perseveration in rats.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2006, Volume: 31, Issue:4

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Analysis of Variance; Animals; Attention; Behavior, Animal; Choice Behavior; Compulsive Behavior; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Antagonists; Fluorobenzenes; Impulsive Behavior; Male; Piperazines; Piperidines; Prefrontal Cortex; Pyridines; Rats; Reaction Time; Receptor, Serotonin, 5-HT1A; Receptor, Serotonin, 5-HT2A; Receptors, N-Methyl-D-Aspartate; Serotonin Antagonists; Serotonin Receptor Agonists

2006
Receptor mediation of exaggerated responses to serotonin-enhancing drugs in serotonin transporter (SERT)-deficient mice.
    Neuropharmacology, 2007, Volume: 53, Issue:5

    Topics: 5-Hydroxytryptophan; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Behavior, Animal; Dose-Response Relationship, Drug; Female; Mice; Mice, Inbred C57BL; Mice, Knockout; Monoamine Oxidase Inhibitors; Piperazines; Piperidines; Polymorphism, Genetic; Pyridines; Receptors, Serotonin; Serotonin Antagonists; Serotonin Plasma Membrane Transport Proteins; Serotonin Receptor Agonists; Serotonin Syndrome; Tranylcypromine

2007
The stimulus effects of 8-OH-DPAT: evidence for a 5-HT2A receptor-mediated component.
    Pharmacology, biochemistry, and behavior, 2008, Volume: 88, Issue:3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Buspirone; Discrimination, Psychological; Dose-Response Relationship, Drug; Fluorobenzenes; Lysergic Acid Diethylamide; Male; Piperazines; Piperidines; Pyridines; Rats; Rats, Inbred F344; Receptor, Serotonin, 5-HT1A; Receptor, Serotonin, 5-HT2A; Serotonin Antagonists; Serotonin Receptor Agonists

2008
Delta(9)-tetrahydrocannabinol prolongs the immobility time in the mouse forced swim test: involvement of cannabinoid CB(1) receptor and serotonergic system.
    European journal of pharmacology, 2008, Jul-28, Volume: 589, Issue:1-3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Behavior, Animal; Brain; Citalopram; Dose-Response Relationship, Drug; Dronabinol; Injections, Intraperitoneal; Male; Mice; Motor Activity; Phenols; Piperazines; Piperidines; Psychotropic Drugs; Pyrazoles; Pyridines; Receptor, Cannabinoid, CB1; Receptor, Serotonin, 5-HT1A; Receptors, Serotonin; Rimonabant; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Succinimides; Sulfonamides; Swimming

2008
Aripiprazole inhibits marble-burying behavior via 5-hydroxytryptamine (5-HT)1A receptor-independent mechanisms.
    European journal of pharmacology, 2008, Sep-11, Volume: 592, Issue:1-3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antipsychotic Agents; Anxiety; Aripiprazole; Behavior, Animal; Benzodiazepines; Catalepsy; Dopamine Agonists; Dopamine D2 Receptor Antagonists; Dose-Response Relationship, Drug; Indoles; Ketanserin; Male; Mice; Mice, Inbred ICR; Olanzapine; Piperazines; Piperidines; Postural Balance; Psychomotor Performance; Pyridines; Quinolones; Quinpirole; Receptor, Serotonin, 5-HT1A; Receptors, Dopamine D2; Serotonin Antagonists; Serotonin Receptor Agonists

2008
Signal transduction and functional selectivity of F15599, a preferential post-synaptic 5-HT1A receptor agonist.
    British journal of pharmacology, 2009, Volume: 156, Issue:2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aminopyridines; Animals; Autoradiography; Binding, Competitive; CHO Cells; Cricetinae; Cricetulus; Extracellular Signal-Regulated MAP Kinases; In Vitro Techniques; Male; Phosphorylation; Piperidines; Prefrontal Cortex; Proto-Oncogene Proteins c-fos; Pyridines; Pyrimidines; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1A; Serotonin 5-HT1 Receptor Agonists; Signal Transduction

2009
Individual differences in the sensitivity to serotonergic drugs: a pharmacobehavioural approach using rats selected on the basis of their response to novelty.
    Psychopharmacology, 2009, Volume: 205, Issue:3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Avoidance Learning; Dose-Response Relationship, Drug; Exploratory Behavior; Fenfluramine; Individuality; Male; Maze Learning; Piperazines; Piperidines; Pyridines; Rats; Selective Serotonin Reuptake Inhibitors; Serotonin Antagonists; Serotonin Receptor Agonists

2009
The potency of different serotonergic agonists in counteracting opioid evoked cardiorespiratory disturbances.
    Philosophical transactions of the Royal Society of London. Series B, Biological sciences, 2009, Sep-12, Volume: 364, Issue:1529

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Analgesics, Opioid; Aniline Compounds; Animals; Blood Pressure; Brain Stem; Cardiovascular Physiological Phenomena; Diaphragm; Electromyography; Fentanyl; Heart; Heart Rate; Histocytochemistry; Phrenic Nerve; Piperidines; Rats; Receptors, Opioid, mu; Serotonin Receptor Agonists; Telemetry; Vascular Resistance

2009
Regulation of serotonin 1B receptor by glycogen synthase kinase-3.
    Molecular pharmacology, 2009, Volume: 76, Issue:6

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Benzamides; Benzazepines; Cell Line; CHO Cells; Cholera Toxin; Colforsin; Cricetinae; Cricetulus; Cyclic AMP; Glycogen Synthase Kinase 3; Humans; Indoles; Male; Maleimides; Mice; Mice, Inbred BALB C; Oxadiazoles; Oximes; Piperidines; Piperidones; Protein Kinase Inhibitors; Purines; Pyridines; Receptor, Serotonin, 5-HT1B; Roscovitine; Serotonin; Spiro Compounds

2009
Evidence that 5-hydroxytryptamine(7) receptors play a role in the mediation of afferent transmission within the nucleus tractus solitarius in anaesthetized rats.
    British journal of pharmacology, 2009, Volume: 158, Issue:5

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Action Potentials; Afferent Pathways; Anesthesia; Animals; Electric Stimulation; Heart; Lung; Male; Neurons; Piperazines; Piperidines; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Serotonin; Serotonin 5-HT1 Receptor Agonists; Serotonin 5-HT1 Receptor Antagonists; Serotonin Antagonists; Solitary Nucleus; Sulfonamides; Synaptic Transmission; Vagus Nerve

2009
Differential effects of serotonin 5-HT1A receptor agonists on the discriminative stimulus effects of the 5-HT2A receptor agonist 1-(2,5-dimethoxy-4-methylphenyl)-2-aminopropane in rats and rhesus monkeys.
    The Journal of pharmacology and experimental therapeutics, 2010, Volume: 333, Issue:1

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aminopyridines; Animals; Discrimination, Psychological; DOM 2,5-Dimethoxy-4-Methylamphetamine; Drug Interactions; Macaca mulatta; Male; Phenethylamines; Piperidines; Rats; Rats, Sprague-Dawley; Serotonin 5-HT1 Receptor Agonists; Serotonin 5-HT2 Receptor Agonists; Tryptamines

2010
The selective 5-HT(1A) receptor antagonist NAD-299 increases acetylcholine release but not extracellular glutamate levels in the frontal cortex and hippocampus of awake rat.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2010, Volume: 20, Issue:7

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Acetylcholine; Animals; Area Under Curve; Benzopyrans; Cholinesterase Inhibitors; Donepezil; Dose-Response Relationship, Drug; Extracellular Fluid; Frontal Lobe; Glutamic Acid; Hippocampus; Indans; Male; Microdialysis; Neostigmine; Piperidines; Rats; Rats, Sprague-Dawley; Serotonin Antagonists; Serotonin Receptor Agonists; Wakefulness

2010
F15599, a preferential post-synaptic 5-HT1A receptor agonist: activity in models of cognition in comparison with reference 5-HT1A receptor agonists.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2010, Volume: 20, Issue:9

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aminopyridines; Animals; Cognition; Disease Models, Animal; Enzyme Inhibitors; Male; Memory, Short-Term; Phencyclidine; Piperidines; Pyrimidines; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1A; Reflex, Startle; Serotonin 5-HT1 Receptor Agonists; Signal Transduction

2010
Role of 5-HT(1A) and 5-HT(1B) receptors in the antidepressant-like effect of piperine in the forced swim test.
    Neuroscience letters, 2011, Oct-24, Volume: 504, Issue:2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Alkaloids; Aminopyridines; Animals; Antidepressive Agents; Benzodioxoles; Data Interpretation, Statistical; Male; Methiothepin; Mice; Mice, Inbred ICR; Motor Activity; Piperazines; Piperidines; Polyunsaturated Alkamides; Propanolamines; Pyridines; Receptor, Serotonin, 5-HT1A; Receptor, Serotonin, 5-HT1B; Serotonin 5-HT1 Receptor Agonists; Serotonin 5-HT1 Receptor Antagonists; Swimming

2011
Effects of cholinesterase inhibitors and serotonin-1A receptor agonists on morphine-induced ventilatory depression and antinociception in rats.
    European journal of pharmacology, 2013, Mar-05, Volume: 703, Issue:1-3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Analgesia; Animals; Buspirone; Cholinesterase Inhibitors; Donepezil; Indans; Male; Morphine; Pain; Physostigmine; Piperidines; Rats; Rats, Wistar; Respiratory Insufficiency; Serotonin 5-HT1 Receptor Agonists

2013
A small-animal pharmacokinetic/pharmacodynamic PET study of central serotonin 1A receptor occupancy by a potential therapeutic agent for overactive bladder.
    PloS one, 2013, Volume: 8, Issue:9

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Administration, Oral; Animals; Computer Simulation; Hippocampus; Microsomes; Piperidines; Positron-Emission Tomography; Protein Binding; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1A; Reflex; Superior Colliculi; Time Factors; Urinary Bladder, Overactive; Urination

2013
Differential pharmacological alleviation of oxaliplatin-induced hyperalgesia/allodynia at cephalic versus extra-cephalic level in rodents.
    Neuropharmacology, 2014, Volume: 79

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amines; Analgesics; Animals; Cold Temperature; Cyclohexanecarboxylic Acids; Dipeptides; Formaldehyde; Gabapentin; gamma-Aminobutyric Acid; Ganglia, Spinal; Hyperalgesia; Male; Mice; Mice, Inbred C57BL; Morphine; Organoplatinum Compounds; Oxaliplatin; Piperazines; Piperidines; Quinazolines; Rats; Rats, Sprague-Dawley; Spinal Cord; Touch; TRPA1 Cation Channel; TRPC Cation Channels; Tryptamines

2014
5-Hydroxytryptamine 1A (5HT1A) receptors mediate increases in plasma glucose independent of corticosterone.
    European journal of pharmacology, 2014, Dec-15, Volume: 745

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Blood Glucose; Corticosterone; Hypoglycemic Agents; Hypothalamus; Insulin; Male; Metyrapone; Mice; Mice, Inbred C57BL; Mifepristone; Piperidines; Receptors, Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists

2014
Antidepressant-like effect of cannabidiol injection into the ventral medial prefrontal cortex-Possible involvement of 5-HT1A and CB1 receptors.
    Behavioural brain research, 2016, Apr-15, Volume: 303

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antidepressive Agents; Arachidonic Acids; Behavior, Animal; Cannabidiol; Endocannabinoids; Male; Motor Activity; Piperazines; Piperidines; Polyunsaturated Alkamides; Prefrontal Cortex; Pyrazoles; Pyridines; Rats; Rats, Wistar; Receptor, Cannabinoid, CB1; Receptor, Serotonin, 5-HT1A; Serotonin 5-HT1 Receptor Agonists; Serotonin Antagonists

2016
Enhanced discriminative stimulus effects of Δ(9)-THC in the presence of cannabidiol and 8-OH-DPAT in rhesus monkeys.
    Drug and alcohol dependence, 2016, Aug-01, Volume: 165

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Cannabidiol; Conditioning, Operant; Discrimination, Psychological; Dose-Response Relationship, Drug; Dronabinol; Drug Synergism; Macaca mulatta; Male; Piperidines; Pyrazoles; Reinforcement Schedule; Rimonabant

2016
Effects of naloxone on motion sickness in cats alone and with broad spectrum antiemetics.
    Autonomic neuroscience : basic & clinical, 2017, Volume: 202

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antiemetics; Cats; Dose-Response Relationship, Drug; Drug Interactions; Emetics; Female; Fentanyl; Models, Animal; Motion Sickness; Naloxone; Neurokinin-1 Receptor Antagonists; Physical Stimulation; Piperidines; Vomiting

2017
Effects of 5-HT
    Psychopharmacology, 2017, Volume: 234, Issue:5

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aminopyridines; Amphetamines; Animals; Conditioning, Operant; Fluorobenzenes; Indoles; Male; Methylphenidate; Piperazines; Piperidines; Pyridines; Rats; Receptor, Serotonin, 5-HT1A; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2C; Reinforcement, Psychology; Serotonin 5-HT1 Receptor Agonists; Serotonin 5-HT1 Receptor Antagonists; Serotonin 5-HT2 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists; Serotonin Antagonists; Serotonin Receptor Agonists

2017
CB1 receptors in the paraventricular nucleus of the hypothalamus modulate the release of 5-HT and GABA to stimulate food intake in rats.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2018, Volume: 28, Issue:11

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Arachidonic Acids; Cyproheptadine; Drug Interactions; Eating; gamma-Aminobutyric Acid; Male; Microinjections; Paraventricular Hypothalamic Nucleus; Piperazines; Piperidines; Piperidones; Pyrazoles; Pyridines; Pyrroles; Rats; Receptor, Cannabinoid, CB1; Receptors, Serotonin, 5-HT1; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Spiro Compounds; Tritium

2018
Serotonin 5-HT
    Neuropharmacology, 2019, 11-01, Volume: 158

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Antipsychotic Agents; Brain Waves; Cortical Synchronization; Dopamine Agonists; Dopamine Antagonists; Electroencephalography; Fluorobenzenes; Gamma Rhythm; Haloperidol; Hippocampus; Locomotion; Mice; Neural Pathways; Piperazines; Piperidines; Prefrontal Cortex; Pyridines; Quinpirole; Receptor, Serotonin, 5-HT1A; Receptor, Serotonin, 5-HT2A; Receptors, Dopamine D2; Risperidone; Serotonin Antagonists; Serotonin Receptor Agonists

2019
Effects of combined 5-HT
    Psychopharmacology, 2020, Volume: 237, Issue:6

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Benzoxazines; Cannabinoid Receptor Antagonists; Cannabinoid Receptor Modulators; Cannabinoids; Dose-Response Relationship, Drug; Drug Therapy, Combination; Fluorobenzenes; Male; Mice; Morpholines; Naphthalenes; Piperidines; Prepulse Inhibition; Receptor, Serotonin, 5-HT2A; Receptors, Cannabinoid; Reflex, Startle; Schizophrenia; Serotonin 5-HT2 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists; Treatment Outcome

2020
Discriminative stimulus properties of the 5-HT1A receptor biased agonists NLX-101 and F13714, in rats trained to discriminate 8-OH-DPAT from saline.
    Behavioural pharmacology, 2021, 12-01, Volume: 32, Issue:8

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aminopyridines; Animals; Buspirone; Discrimination Learning; Dose-Response Relationship, Drug; Female; Male; Piperazines; Piperidines; Pyridines; Pyrimidines; Rats; Rats, Sprague-Dawley; Serotonin 5-HT1 Receptor Agonists

2021
The selective 5-HT 1A receptor agonist, NLX-112, overcomes tetrabenazine-induced catalepsy and depression-like behavior in the rat.
    Behavioural pharmacology, 2022, 08-01, Volume: 33, Issue:5

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antidepressive Agents; Buspirone; Catalepsy; Depression; Huntington Disease; Parkinsonian Disorders; Piperidines; Pyridines; Rats; Receptor, Serotonin, 5-HT1A; Serotonin; Serotonin 5-HT1 Receptor Agonists; Serotonin Receptor Agonists; Tetrabenazine

2022