8-hydroxy-2-(di-n-propylamino)tetralin has been researched along with paroxetine in 57 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 30 (52.63) | 18.2507 |
| 2000's | 22 (38.60) | 29.6817 |
| 2010's | 5 (8.77) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cortizo, L; García, N; Innerárity, A; Labeaga, L; Mosquera, R; Orjales, A; Pumar, MC; Toledo, A | 1 |
| Betti, L; Caputo, F; Clerici, F; Fabbrini, L; Gelmi, ML; Giannaccini, G; Lucacchini, A; Palego, L; Pellegrino, S; Schmid, L | 1 |
| Buck, LB; Petrascheck, M; Ye, X | 1 |
| Bell, J; Whitaker-Azmitia, PM; Zhang, XN | 1 |
| Ben-Zeev, A; Lerer, B; Newman, ME | 1 |
| Blier, P; Chaput, Y; de Montigny, C | 1 |
| Bird, ED; Crino, PB; Plager, MD; Vogt, BA | 1 |
| Crino, PB; Vogt, BA; Volicer, L; Wiley, RG | 1 |
| Doucet, E; Hamon, M; Laaris, N; Lanfumey, L; Laporte, AM; Le Poul, E | 1 |
| Hyttel, J; Sánchez, C | 1 |
| Gobbi, M; Mennini, T; Palacios, JM; Pompeiano, M; Regondi, MC | 1 |
| Berendsen, HH; Broekkamp, CL | 1 |
| Frankfurt, M; McEwen, BS; McKittrick, CR; Mendelson, SD | 1 |
| Pranzatelli, MR | 1 |
| Cheng, CH; Costall, B; Naylor, RJ; Rudd, JA | 1 |
| Clark, M; Post, RM; Weiss, SR | 1 |
| Cumming, P; Gjedde, A | 1 |
| Battaglia, G; Pinto, W | 1 |
| McEwen, BS; Mendelson, S; Sakai, RR; Watanabe, Y | 1 |
| Dudley, MW; McCarty, DR; Sprouse, JS | 1 |
| Arranz, B; Eriksson, A; Marcusson, J; Mellerup, E; Plenge, P | 1 |
| Gartside, SE; Hajós, M; Sharp, T; Villa, AE | 1 |
| Haycock, JW; Lowy, MT; Shapiro, LA; Stockmeier, CA; Thompson, PA | 1 |
| Bijak, M; Dziedzicka-Wasylewska, M; Maj, J; Rogoz, R; Rogóz, Z; Skuza, G; Tokarski, T | 1 |
| Gartside, SE; Sharp, T; Umbers, V | 1 |
| Battaglia, G; Li, Q; Muma, NA; Van de Kar, LD | 1 |
| Auerbach, SB; Gundlah, C; Heal, DJ; Martin, KF | 1 |
| Cryan, JF; Leonard, BE; McGrath, C; Norman, TR | 2 |
| Alder, JT; Bray, L; Chen, CP; Foster, OJ; Francis, PT; Kingsbury, AE | 1 |
| Baker, GB; Bourin, M; Colombel, MC; Redrobe, JP | 1 |
| Abe, S; Baba, A; Hori, T; Shiraishi, H; Suzuki, T; Yamamoto, T | 1 |
| Hajós, M; Hajós-Korcsok, E; Sharp, T | 1 |
| Duxon, MS; Starr, KR; Upton, N | 1 |
| Blier, P; Gobbi, G; Lesch, K; Murphy, DL | 1 |
| Abramov, U; Beljajev, S; Bourin, M; Kõks, S; Koovit, I; Vasar, E | 1 |
| Borsini, F; Brambilla, A; Cesana, R; Grippa, N | 1 |
| Alberti, I; Boni, C; De Felipe, C; Froger, N; Gardier, AM; Hamon, M; Hunt, SP; Jacquot, C; Lanfumey, L; Lena, I; Moratalla, R; Rupniak, NM | 1 |
| Blier, P; Szabo, ST | 1 |
| Aida, R; Akiyama, M; Moriya, T; Shibata, S; Shimomura, H; Takahashi, S; Yoshinobu, Y | 1 |
| Duncan, MJ; Hensler, JG | 1 |
| Marsden, CA; Mason, R; Muchimapura, S | 1 |
| Astier, B; Blier, P; Chouvet, G; Debonnel, G; Faure, C; Haddjeri, N; Lucas, G; Mnie-Filali, O; Renaud, B | 1 |
| Camarasa, J; Escubedo, E; Farré, A; Fisas, MA | 1 |
| Cools, AR; de Jong, TR; Olivier, B; Pattij, T; Veening, JG; Waldinger, MD | 1 |
| Bartoszyk, GD; Dawson, LA; Hagan, JJ; Hill, M; Hughes, ZA; Langmead, CJ; Middlemiss, DN; Starr, KR | 1 |
| Battaglia, G; Carrasco, GA; Chen, Z; Muma, NA; Shankaran, M; Sripathirathan, K; Tetzlaff, J; Van De Kar, LD | 1 |
| Cools, AR; de Jong, TR; Dederen, PJ; Olivier, B; Pattij, T; Veening, JG; Waldinger, MD | 1 |
| Cools, AR; de Jong, TR; Olivier, B; Pattij, T; Snaphaan, LJ; Veening, JG; Waldinger, MD | 1 |
| Bourin, M; Chenu, F; David, DJ; Gardier, AM; Guiard, BP; Guilloux, JP; Repérant, C; Toth, M | 1 |
| Andrews, AM; Chenu, F; David, DJ; Deltheil, T; Gardier, AM; Guiard, BP; Hamon, M; Hen, R; Lanfumey, L; Le Maître, E; Leroux-Nicollet, I; Renoir, T; Sokoloff, P | 1 |
| Borah, M; Radhakrishnan, M; Ramamoorthy, R | 1 |
| Chan, JS; de Jong, TR; Olivier, B; Oosting, RS; Snoeren, EM; Waldinger, MD | 1 |
| Cheng, FC; Feng, JJ; Lin, CH; Wei, JW; Yang, SD | 1 |
| Seftel, A | 1 |
| Seyfried, CA; van Amsterdam, C | 1 |
| Ishii, T; Iwai, M; Kinoshita, K; Muroi, Y | 1 |
57 other study(ies) available for 8-hydroxy-2-(di-n-propylamino)tetralin and paroxetine
| Article | Year |
|---|---|
Syntheses and binding studies of new [(aryl)(aryloxy)methyl]piperidine derivatives and related compounds as potential antidepressant drugs with high affinity for serotonin (5-HT) and norepinephrine (NE) transporters.
Topics: Adrenergic Uptake Inhibitors; Animals; Antidepressive Agents; Brain; Carrier Proteins; Fluoxetine; In Vitro Techniques; Male; Membrane Glycoproteins; Membrane Transport Proteins; Morpholines; Nerve Tissue Proteins; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Piperidines; Radioligand Assay; Rats; Rats, Wistar; Reboxetine; Receptor, Serotonin, 5-HT1A; Receptor, Serotonin, 5-HT2A; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Plasma Membrane Transport Proteins; Stereoisomerism; Structure-Activity Relationship; Symporters | 2003 |
1-Aminocyclopentane-1,2,4-tricarboxylic acids screening on glutamatergic and serotonergic systems.
Topics: Animals; Cells, Cultured; Cyclopentanes; Drug Evaluation, Preclinical; Humans; Molecular Structure; Rats; Receptors, Glutamate; Receptors, Serotonin; Serotonin Receptor Agonists; Stereoisomerism; Tricarboxylic Acids | 2007 |
An antidepressant that extends lifespan in adult Caenorhabditis elegans.
Topics: Aging; Animals; Antidepressive Agents; Caenorhabditis elegans; Caloric Restriction; Humans; Longevity; Methiothepin; Mianserin; Octopamine; Receptors, Biogenic Amine; Receptors, Serotonin, 5-HT4; Serotonin; Serotonin 5-HT4 Receptor Antagonists; Serotonin Antagonists; Signal Transduction; Starvation | 2007 |
5-HT3 receptor-active drugs alter development of spinal serotonergic innervation: lack of effect of other serotonergic agents.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aging; Animals; Biguanides; Female; Fenfluramine; Hypoglycemic Agents; Maternal-Fetal Exchange; Neurons; Pain; Paroxetine; Piperazines; Piperidines; Pregnancy; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Spinal Cord; Tetrahydronaphthalenes; Tropanes | 1992 |
Chloroamphetamine did not prevent the effects of chronic antidepressants on 5-hydroxytryptamine inhibition of forskolin-stimulated adenylate cyclase in rat hippocampus.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Antidepressive Agents; Binding Sites; Cerebral Cortex; Chlorides; Colforsin; Hippocampus; Imipramine; Lithium; Lithium Chloride; Male; p-Chloroamphetamine; Paroxetine; Piperidines; Rats; Serotonin; Synapses; Tetrahydronaphthalenes | 1991 |
Presynaptic and postsynaptic modifications of the serotonin system by long-term administration of antidepressant treatments. An in vivo electrophysiologic study in the rat.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antidepressive Agents; Electric Stimulation; Electrophysiology; Hippocampus; Imipramine; Male; Neurons; Paroxetine; Piperidines; Pyramidal Tracts; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Synapses; Tetrahydronaphthalenes | 1991 |
Laminar distributions of muscarinic acetylcholine, serotonin, GABA and opioid receptors in human posterior cingulate cortex.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aged; Autoradiography; Cerebral Cortex; Dynorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Female; Humans; Iodocyanopindolol; Ketanserin; Male; Middle Aged; Oxotremorine; Paroxetine; Pindolol; Piperidines; Pirenzepine; Receptors, Cell Surface; Receptors, Cholinergic; Receptors, GABA-A; Receptors, Muscarinic; Receptors, Opioid; Receptors, Serotonin; Serotonin; Tetrahydronaphthalenes | 1990 |
Cellular localization of serotonin 1A, 1B and uptake sites in cingulate cortex of the rat.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Cerebral Cortex; Immunotoxins; Iodocyanopindolol; Male; Paroxetine; Pindolol; Piperidines; Rats; Receptors, Serotonin; Serotonin; Tetrahydronaphthalenes | 1990 |
Early desensitization of somato-dendritic 5-HT1A autoreceptors in rats treated with fluoxetine or paroxetine.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Autoradiography; Brain Stem; Electrophysiology; Fluoxetine; In Vitro Techniques; Male; Neurons; Paroxetine; Piperazines; Pyridines; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists | 1995 |
Isolation-induced aggression in mice: effects of 5-hydroxytryptamine uptake inhibitors and involvement of postsynaptic 5-HT1A receptors.
Topics: 1-Naphthylamine; 5-Hydroxytryptophan; 8-Hydroxy-2-(di-n-propylamino)tetralin; Aggression; Analysis of Variance; Animals; Behavior, Animal; Brain; Citalopram; Dose-Response Relationship, Drug; Fenclonine; Fluoxetine; Fluvoxamine; Male; Mice; Paroxetine; Penbutolol; Piperidines; Rats; Rats, Wistar; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Selective Serotonin Reuptake Inhibitors; Sertraline; Synaptosomes | 1994 |
Differential effects of 5,7-dihydroxytryptamine-induced serotoninergic degeneration of 5-HT1A receptors and 5-HT uptake sites in the rat brain.
Topics: 5,7-Dihydroxytryptamine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Autoradiography; Brain; Citalopram; Male; Nerve Degeneration; Paroxetine; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Reserpine; Serotonin | 1994 |
Comparison of stimulus properties of fluoxetine and 5-HT receptor agonists in a conditioned taste aversion procedure.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Analysis of Variance; Animals; Avoidance Learning; Conditioning, Classical; Fluoxetine; Male; Mice; Paroxetine; Pyrazines; Serotonin Receptor Agonists; Taste | 1994 |
Effect of 5,7-dihydroxytryptamine, ovariectomy and gonadal steroids on serotonin receptor binding in rat brain.
Topics: 5,7-Dihydroxytryptamine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Autoradiography; Brain Chemistry; Carrier Proteins; Estrogens; Female; Gonadal Steroid Hormones; Hippocampus; Iodocyanopindolol; Male; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Orchiectomy; Ovariectomy; Paroxetine; Pindolol; Progesterone; Rats; Receptors, Serotonin; Serotonin Plasma Membrane Transport Proteins; Ventromedial Hypothalamic Nucleus | 1994 |
Dissociation of the plasticity of 5-HT1A sites and 5-HT transporter sites.
Topics: 5,7-Dihydroxytryptamine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Animals, Newborn; Brain; Carrier Proteins; Kinetics; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Organ Specificity; Paroxetine; Rats; Receptors, Serotonin; Reference Values; Serotonin; Serotonin Plasma Membrane Transport Proteins; Spinal Cord; Tritium | 1994 |
The effect of 5-HT receptor ligands on the uptake of [3H]5-hydroxytryptamine into rat cortical synaptosomes.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Cerebral Cortex; Cocaine; Desipramine; Female; Fluoxetine; In Vitro Techniques; Indoles; Neurotransmitter Uptake Inhibitors; Paroxetine; Piperazines; Rats; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Synaptosomes; Tropisetron | 1993 |
Autoradiographic analysis of serotonin receptors and transporter in kindled rat brain.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amygdala; Animals; Autoradiography; Cerebral Cortex; Hippocampus; Iodine Radioisotopes; Iodocyanopindolol; Kindling, Neurologic; Male; Paroxetine; Pindolol; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Receptors, Serotonin; Seizures; Tritium | 1993 |
Kinetics of the uptake of [3H]paroxetine in the rat brain.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antipyrine; Autoradiography; Blood Volume; Blood-Brain Barrier; Brain; Fluoxetine; Male; Paroxetine; Rats; Rats, Wistar; Receptors, Serotonin; Tomography, Emission-Computed | 1993 |
In vivo EEDQ dose-dependently inactivates rat brain 5-HT receptors but not 5-HT uptake sites.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Analysis of Variance; Animals; Brain; Carrier Proteins; Cerebral Cortex; Dose-Response Relationship, Drug; Iodocyanopindolol; Ketanserin; Kinetics; Male; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Paroxetine; Pindolol; Quinolines; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Serotonin Plasma Membrane Transport Proteins | 1993 |
Stress and antidepressant effects on hippocampal and cortical 5-HT1A and 5-HT2 receptors and transport sites for serotonin.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antidepressive Agents; Antidepressive Agents, Tricyclic; Autoradiography; Carrier Proteins; Cerebral Cortex; Corticosterone; Hippocampus; Imipramine; Male; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Paroxetine; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Restraint, Physical; Serotonin; Serotonin Plasma Membrane Transport Proteins; Stress, Psychological; Thiazepines | 1993 |
Apparent regional differences in 5-HT1A binding may reflect [3H]8-OH-DPAT labeling of serotonin uptake sites.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Binding, Competitive; Cattle; Female; Hippocampus; Membranes; Paroxetine; Radioligand Assay; Raphe Nuclei; Serotonin; Tritium | 1993 |
Effect of aging in human cortical pre- and postsynaptic serotonin binding sites.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adolescent; Adult; Aged; Aging; Binding Sites; Female; Frontal Lobe; Humans; Ketanserin; Male; Middle Aged; Paroxetine; Radioligand Assay; Serotonin; Synapses | 1993 |
Evidence for a repetitive (burst) firing pattern in a sub-population of 5-hydroxytryptamine neurons in the dorsal and median raphe nuclei of the rat.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Anesthetics; Animals; Electrophysiology; Male; Neurons; Paroxetine; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Receptor Agonists | 1995 |
Quantitative subregional distribution of serotonin1A receptors and serotonin transporters in the human dorsal raphe.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Age Factors; Aged; Autoradiography; Carrier Proteins; Humans; Immunohistochemistry; Male; Membrane Glycoproteins; Membrane Transport Proteins; Mesencephalon; Middle Aged; Nerve Tissue Proteins; Paroxetine; Postmortem Changes; Radioligand Assay; Raphe Nuclei; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Plasma Membrane Transport Proteins; Tritium; Tryptophan Hydroxylase | 1996 |
The effects of paroxetine given repeatedly on the 5-HT receptor subpopulations in the rat brain.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Behavior, Animal; Brain Chemistry; Electrophysiology; Hippocampus; Imipramine; Male; Motor Activity; Paroxetine; Piperazines; Rats; Rats, Wistar; Receptors, Serotonin; Selective Serotonin Reuptake Inhibitors; Serotonin Receptor Agonists | 1996 |
Inhibition of 5-HT cell firing in the DRN by non-selective 5-HT reuptake inhibitors: studies on the role of 5-HT1A autoreceptors and noradrenergic mechanisms.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Action Potentials; Amitriptyline; Animals; Clomipramine; Cyclohexanols; Male; Neurons; Paroxetine; Piperazines; Pyridines; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Venlafaxine Hydrochloride | 1997 |
A desensitization of hypothalamic 5-HT1A receptors by repeated injections of paroxetine: reduction in the levels of G(i) and G(o) proteins and neuroendocrine responses, but not in the density of 5-HT1A receptors.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenocorticotropic Hormone; Animals; Autoradiography; GTP-Binding Proteins; Hypothalamus; Male; Oxytocin; Paroxetine; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Selective Serotonin Reuptake Inhibitors | 1997 |
In vivo criteria to differentiate monoamine reuptake inhibitors from releasing agents: sibutramine is a reuptake inhibitor.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Cyclobutanes; Fenfluramine; Fluoxetine; Male; Microdialysis; Paroxetine; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Serotonin | 1997 |
Combining pindolol and paroxetine in an animal model of chronic antidepressant action--can early onset of action be detected?
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic beta-Antagonists; Animals; Antidepressive Agents; Depression; Disease Models, Animal; Drug Therapy, Combination; Exploratory Behavior; Hypothermia; Male; Olfactory Bulb; Paroxetine; Pindolol; Rats; Rats, Sprague-Dawley; Serotonin Receptor Agonists | 1998 |
Post-synaptic 5-HT1A and 5-HT2A receptors are increased in Parkinson's disease neocortex.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Humans; Ketanserin; Kinetics; Neocortex; Parkinson Disease; Paroxetine; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Reference Values | 1998 |
Psychopharmacological profile of the selective serotonin reuptake inhibitor, paroxetine: implication of noradrenergic and serotonergic mechanisms.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amines; Animals; Antidepressive Agents; Apomorphine; Brain; Clonidine; Dopamine Agonists; Dose-Response Relationship, Drug; Drug Interactions; Hypothermia; Indoles; Male; Mice; Motor Activity; Norepinephrine; Paroxetine; Pindolol; Piperazines; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Swimming | 1998 |
Effects of chronic administration of interferon alpha A/D on serotonergic receptors in rat brain.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Brain; Carrier Proteins; Cell Membrane; Cerebral Cortex; Hippocampus; Interferon Type I; Ketanserin; Male; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Paroxetine; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Recombinant Proteins; Selective Serotonin Reuptake Inhibitors; Serotonin Antagonists; Serotonin Plasma Membrane Transport Proteins; Tritium | 1999 |
Onset of the effects of the 5-HT1A antagonist, WAY-100635, alone, and in combination with paroxetine, on olfactory bulbectomy and 8-OH-DPAT-induced changes in the rat.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antidepressive Agents, Second-Generation; Depression; Disease Models, Animal; Drug Synergism; Exploratory Behavior; Hypothermia; Male; Motor Activity; Olfactory Bulb; Paroxetine; Piperazines; Pyridines; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Serotonin Antagonists; Serotonin Receptor Agonists | 1999 |
Role of the medial prefrontal cortex in 5-HT1A receptor-induced inhibition of 5-HT neuronal activity in the rat.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Electrophysiology; Immunohistochemistry; Iontophoresis; Male; Microinjections; Neurons; Oncogene Proteins v-fos; Paroxetine; Piperazines; Prefrontal Cortex; Putamen; Pyridines; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists | 1999 |
Latency to paroxetine-induced anxiolysis in the rat is reduced by co-administration of the 5-HT(1A) receptor antagonist WAY100635.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Anti-Anxiety Agents; Anxiety; Disease Models, Animal; Drug Interactions; Hyperkinesis; Interpersonal Relations; Male; Paroxetine; Piperazines; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Antagonists | 2000 |
Modifications of the serotonergic system in mice lacking serotonin transporters: an in vivo electrophysiological study.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Carrier Proteins; Electrophysiology; Hippocampus; Infusions, Intravenous; Membrane Glycoproteins; Membrane Transport Proteins; Mice; Mice, Knockout; Nerve Tissue Proteins; Neurons; Paroxetine; Piperazines; Pyramidal Tracts; Pyridines; Raphe Nuclei; Receptors, Serotonin; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Antagonists; Serotonin Plasma Membrane Transport Proteins; Serotonin Receptor Agonists; Time Factors | 2001 |
8-OH-DPAT, but not deramciclane, antagonizes the anxiogenic-like action of paroxetine in an elevated plus-maze.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Anxiety; Camphanes; Exploratory Behavior; Male; Motor Activity; Paroxetine; Rats; Rats, Wistar; Receptors, Serotonin; Selective Serotonin Reuptake Inhibitors; Serotonin Antagonists; Serotonin Receptor Agonists | 2001 |
Lack of interaction between flibanserin and antidepressants in inducing serotonergic syndrome in rats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antidepressive Agents; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Benzimidazoles; Drug Interactions; Fluoxetine; Imipramine; Male; Paroxetine; Rats; Rats, Sprague-Dawley; Serotonin Receptor Agonists; Serotonin Syndrome | 2001 |
5-hydroxytryptamine (5-HT)1A autoreceptor adaptive changes in substance P (neurokinin 1) receptor knock-out mice mimic antidepressant-induced desensitization.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antidepressive Agents; Autoreceptors; Drug Resistance; Electrophysiology; Immunohistochemistry; In Vitro Techniques; Male; Mice; Mice, Knockout; Neurons; Paroxetine; Piperazines; Pyridines; Pyrimidines; Raphe Nuclei; Receptors, Neurokinin-1; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; RNA, Messenger; Selective Serotonin Reuptake Inhibitors; Serotonin Antagonists; Serotonin Receptor Agonists; Substance P | 2001 |
Functional and pharmacological characterization of the modulatory role of serotonin on the firing activity of locus coeruleus norepinephrine neurons.
Topics: 5,7-Dihydroxytryptamine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Antagonists; Amphetamines; Animals; Electric Stimulation; Electrophysiology; Fluorobenzenes; Idazoxan; Locus Coeruleus; Male; Neurons; Norepinephrine; Paroxetine; Patch-Clamp Techniques; Piperazines; Piperidines; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Antagonists | 2001 |
Extended action of MKC-242, a selective 5-HT(1A) receptor agonist, on light-induced Per gene expression in the suprachiasmatic nucleus in mice.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Buspirone; Cell Cycle Proteins; Circadian Rhythm; Diazepam; Dioxanes; Dioxoles; GABA Modulators; Gene Expression Regulation; In Situ Hybridization; Light; Male; Mice; Motor Activity; Nuclear Proteins; Paroxetine; Period Circadian Proteins; Piperazines; Pyridines; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; RNA, Messenger; Selective Serotonin Reuptake Inhibitors; Serotonin Antagonists; Serotonin Receptor Agonists; Suprachiasmatic Nucleus; Transcription Factors | 2002 |
Aging alters in a region-specific manner serotonin transporter sites and 5-HT(1A) receptor-G protein interactions in hamster brain.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aging; Animals; Autoradiography; Binding, Competitive; Brain; Carrier Proteins; Cricetinae; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Hippocampus; Male; Membrane Glycoproteins; Membrane Transport Proteins; Mesocricetus; Nerve Tissue Proteins; Paroxetine; Piperazines; Pyridines; Raphe Nuclei; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Selective Serotonin Reuptake Inhibitors; Serotonin Antagonists; Serotonin Plasma Membrane Transport Proteins; Serotonin Receptor Agonists | 2002 |
Effect of isolation rearing on pre- and post-synaptic serotonergic function in the rat dorsal hippocampus.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Carbachol; Cholinergic Agonists; Fluoxetine; Hippocampus; In Vitro Techniques; Male; Motor Activity; Neurons; Paroxetine; Presynaptic Terminals; Rats; Rats, Inbred Strains; Receptor, Serotonin, 5-HT1B; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Social Isolation; Synapses | 2003 |
In-vivo modulation of central 5-hydroxytryptamine (5-HT1A) receptor-mediated responses by the cholinergic system.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Atropine; Body Temperature; Male; Motor Activity; Muscarinic Antagonists; Neurons; Parasympathetic Nervous System; Paroxetine; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1A; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Receptor Agonists; Swimming | 2004 |
Effects of lesopitron on the central nervous system arising from its interaction with 5-HT1A receptors.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Catalepsy; Central Nervous System; Central Nervous System Depressants; Drug Interactions; Female; Hippocampus; Hypothermia; In Vitro Techniques; Ligands; Male; Mice; Paroxetine; Piperazines; Pyrimidines; Radioligand Assay; Rats; Rats, Sprague-Dawley; Rats, Wistar; Selective Serotonin Reuptake Inhibitors; Serotonin 5-HT1 Receptor Agonists; Serotonin Syndrome; Species Specificity | 2004 |
Effects of chronic selective serotonin reuptake inhibitors on 8-OH-DPAT-induced facilitation of ejaculation in rats: comparison of fluvoxamine and paroxetine.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Ejaculation; Female; Fluvoxamine; Male; Paroxetine; Rats; Rats, Wistar; Selective Serotonin Reuptake Inhibitors; Serotonin Receptor Agonists; Sexual Behavior, Animal | 2005 |
Neurochemical evaluation of the novel 5-HT1A receptor partial agonist/serotonin reuptake inhibitor, vilazodone.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Benzofurans; Benzylamines; Binding, Competitive; Cell Membrane; Dopamine; Dose-Response Relationship, Drug; Extracellular Space; Frontal Lobe; Guanosine 5'-O-(3-Thiotriphosphate); Hippocampus; Indoles; Male; Microdialysis; Norepinephrine; Paroxetine; Piperazines; Piperidones; Pyridines; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin 5-HT1 Receptor Agonists; Serotonin Antagonists; Serotonin Receptor Agonists; Spiro Compounds; Sulfur Radioisotopes; Time Factors; Tritium; Vilazodone Hydrochloride | 2005 |
Paroxetine is effective in desensitizing 5-HT1A receptor function in adult offspring exposed prenatally to cocaine.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenocorticotropic Hormone; Animals; Cocaine; Corticosterone; Female; Fetus; Growth; Oxytocin; Paroxetine; Piperazines; Pregnancy; Prolactin; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1A; Renin; Weight Gain | 2005 |
Effects of chronic paroxetine pretreatment on (+/-)-8-hydroxy-2-(di-n-propyl-amino)tetralin induced c-fos expression following sexual behavior.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Brain; Ejaculation; Female; Immunohistochemistry; Male; Oxytocin; Paroxetine; Proto-Oncogene Proteins c-fos; Rats; Rats, Wistar; Selective Serotonin Reuptake Inhibitors; Serotonin Receptor Agonists; Sexual Behavior, Animal | 2005 |
Effects of chronic treatment with fluvoxamine and paroxetine during adolescence on serotonin-related behavior in adult male rats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Acoustic Stimulation; Analysis of Variance; Animals; Behavior, Animal; Body Weight; Dose-Response Relationship, Radiation; Drug Interactions; Fluvoxamine; Inhibition, Psychological; Male; Maze Learning; Paroxetine; Rats; Rats, Wistar; Reaction Time; Reflex, Startle; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Receptor Agonists; Sexual Behavior, Animal; Swimming | 2006 |
Blockade of 5-HT1A receptors by (+/-)-pindolol potentiates cortical 5-HT outflow, but not antidepressant-like activity of paroxetine: microdialysis and behavioral approaches in 5-HT1A receptor knockout mice.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Analysis of Variance; Animals; Area Under Curve; Behavior, Animal; Cerebral Cortex; Dose-Response Relationship, Drug; Drug Interactions; Immobility Response, Tonic; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Microdialysis; Paroxetine; Pindolol; Raphe Nuclei; Receptor, Serotonin, 5-HT1A; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Swimming | 2006 |
Brain-derived neurotrophic factor-deficient mice exhibit a hippocampal hyperserotonergic phenotype.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Autoradiography; Brain Chemistry; Brain-Derived Neurotrophic Factor; Citalopram; Dose-Response Relationship, Drug; Electrophysiology; Hippocampus; Male; Mice; Mice, Knockout; Microdialysis; Paroxetine; Phenotype; Raphe Nuclei; Receptor, Serotonin, 5-HT1A; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Plasma Membrane Transport Proteins; Serotonin Receptor Agonists; Synaptic Transmission | 2008 |
Antidepressant-like effects of serotonin type-3 antagonist, ondansetron: an investigation in behaviour-based rodent models.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antidepressive Agents; Behavior, Animal; Cyclohexanols; Desipramine; Dose-Response Relationship, Drug; Drug Interactions; Drug Therapy, Combination; Exploratory Behavior; Fluoxetine; Hindlimb Suspension; Male; Maze Learning; Mice; Motor Activity; Olfactory Bulb; Ondansetron; Paroxetine; Rats; Rats, Wistar; Serotonin 5-HT3 Receptor Agonists; Serotonin 5-HT3 Receptor Antagonists; Stress, Psychological; Venlafaxine Hydrochloride | 2008 |
A new female rat animal model for hypoactive sexual desire disorder; behavioral and pharmacological evidence.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Apomorphine; Disease Models, Animal; Dopamine Agonists; Female; Male; Paroxetine; Rats; Rats, Wistar; Selective Serotonin Reuptake Inhibitors; Serotonin 5-HT1 Receptor Agonists; Sexual Behavior, Animal; Sexual Dysfunctions, Psychological | 2011 |
Characterization of 5-HT transporter and receptor system in HeLaS3 cells by [(3)H]8-OH-DPAT and other serotonergic ligands.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Binding, Competitive; Biogenic Amines; Cocaine; Fluoxetine; HeLa Cells; Humans; Kinetics; Ligands; Paroxetine; Radioligand Assay; Receptors, Serotonin; Selective Serotonin Reuptake Inhibitors; Serotonin Plasma Membrane Transport Proteins; Vesicular Biogenic Amine Transport Proteins | 2011 |
Re: A new female rat animal model for hypoactive sexual desire disorder; behavioral and pharmacological evidence.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Apomorphine; Dopamine Agonists; Female; Male; Paroxetine; Selective Serotonin Reuptake Inhibitors; Serotonin 5-HT1 Receptor Agonists; Sexual Dysfunctions, Psychological | 2011 |
Mechanism of action of the bimodal antidepressant vilazodone: evidence for serotonin1A-receptor-mediated auto-augmentation of extracellular serotonin output.
Topics: 5-Hydroxytryptophan; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antidepressive Agents; Benzofurans; Brain; Citalopram; Dose-Response Relationship, Drug; Drug Interactions; Extracellular Space; Fluoxetine; Indoles; Male; Paroxetine; Piperazines; Pyridines; Rats, Wistar; Receptor, Serotonin, 5-HT1A; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin 5-HT1 Receptor Agonists; Serotonin Antagonists; Serotonin Receptor Agonists; Vilazodone Hydrochloride | 2014 |
Serotonin modulates the dehydration-induced changes in tolerance for bitter water.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Dehydration; Drinking; Drinking Behavior; Drinking Water; Food Preferences; Male; Mice, Inbred BALB C; Models, Animal; Paroxetine; Proto-Oncogene Proteins c-fos; Quinine; Raphe Nuclei; Selective Serotonin Reuptake Inhibitors; Serotonergic Neurons; Serotonin; Time Factors; Tryptophan Hydroxylase; Water Deprivation | 2015 |