8-hydroxy-2-(di-n-propylamino)tetralin and n-methyl-3,4-methylenedioxyamphetamine

8-hydroxy-2-(di-n-propylamino)tetralin has been researched along with n-methyl-3,4-methylenedioxyamphetamine in 25 studies

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (16.00)18.2507
2000's14 (56.00)29.6817
2010's7 (28.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Glennon, RA1
Insel, TR; Winslow, JT1
Poland, RE1
Kelly, JP; Leonard, BE; McNamara, MG1
Aguirre, N; Ballaz, S; Del Río, J; Lasheras, B1
Glennon, RA; Young, R1
Ashby, CR; Granoff, MI1
Biello, SM; Dafters, RI1
Biello, SM; Colbron, S; Jones, M1
Colado, MI; Elliott, JM; Green, AR; O'shea, E; Saadat, KS1
Meyer, JS; Oliver, AJ; Piper, BJ; Safain, MG; Vu, HL1
Gudelsky, GA; Nair, SG1
Chang-Fong, J; Dukat, M; El-Zahabi, M; Glennon, RA; Young, R1
Callaghan, PD; Cornish, JL; Hunt, GE; McGregor, IS; Thompson, MR1
Betti, L; Fabbrini, L; Fabiani, O; Giannaccini, G; Giusiani, M; Giusti, L; Lucacchini, A; Macchia, M; Martini, C; Mascia, G; Palego, L; Pirone, A1
DiMicco, JA; Rusyniak, DE; Zaretskaia, MV; Zaretsky, DV1
Callaghan, PD; Hunt, GE; McGregor, IS; Thompson, MR1
El Yacoubi, M; Hamon, M; Hanoun, N; Lanfumey, L; Lesch, KP; Melfort, M; Païzanis, E; Renoir, T; Saurini, F1
Glennon, RA; Khorana, N; Young, R1
Karrenbauer, B; Natusch, C; Sadananda, M; Schwarting, RK1
Abraham, B; Aronsen, D; Colussi-Mas, J; Do, J; Schenk, S1
Gogos, A; Thwaites, SJ; Van den Buuse, M1
Aronsen, D; Schenk, S1
Aronsen, D; Bukholt, N; Foote, J; Highgate, Q; Schenk, S; Van de Wetering, R; Webster, J1
Gołembiowska, K; Kamińska, K; Kreiner, G; Noworyta-Sokołowska, K; Rogóż, Z1

Other Studies

25 other study(ies) available for 8-hydroxy-2-(di-n-propylamino)tetralin and n-methyl-3,4-methylenedioxyamphetamine

ArticleYear
The 2014 Philip S. Portoghese Medicinal Chemistry Lectureship: The "Phenylalkylaminome" with a Focus on Selected Drugs of Abuse.
    Journal of medicinal chemistry, 2017, 04-13, Volume: 60, Issue:7

    Topics: Animals; Central Nervous System Stimulants; Chemistry, Pharmaceutical; Dopamine; Drug Discovery; Hallucinogens; Humans; Illicit Drugs; Norepinephrine; Phenethylamines; Psychotropic Drugs; Receptors, Serotonin; Serotonin

2017
Serotonergic modulation of rat pup ultrasonic vocal development: studies with 3,4-methylenedioxymethamphetamine.
    The Journal of pharmacology and experimental therapeutics, 1990, Volume: 254, Issue:1

    Topics: 3,4-Methylenedioxyamphetamine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; N-Methyl-3,4-methylenedioxyamphetamine; Piperazines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Tetrahydronaphthalenes; Ultrasonics; Vocalization, Animal

1990
Diminished corticotropin and enhanced prolactin responses to 8-hydroxy-2(di-n-propylamino)tetralin in methylenedioxymethamphetamine pretreated rats.
    Neuropharmacology, 1990, Volume: 29, Issue:11

    Topics: 3,4-Methylenedioxyamphetamine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenocorticotropic Hormone; Animals; Drug Interactions; Male; N-Methyl-3,4-methylenedioxyamphetamine; Prolactin; Rats; Rats, Inbred Strains; Reference Values; Serotonin Antagonists; Tetrahydronaphthalenes

1990
Some behavioural and neurochemical aspects of subacute (+/-)3,4-methylenedioxymethamphetamine administration in rats.
    Pharmacology, biochemistry, and behavior, 1995, Volume: 52, Issue:3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic Uptake Inhibitors; Animals; Behavior, Animal; Biogenic Amines; Body Temperature; Brain Chemistry; Corticosterone; Dose-Response Relationship, Drug; Male; Motor Activity; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Rats, Sprague-Dawley

1995
MDMA ('Ecstasy') enhances 5-HT1A receptor density and 8-OH-DPAT-induced hypothermia: blockade by drugs preventing 5-hydroxytryptamine depletion.
    European journal of pharmacology, 1998, Apr-10, Volume: 346, Issue:2-3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Body Temperature; Hydroxyindoleacetic Acid; Hypothalamus; Hypothermia; Male; N-Methyl-3,4-methylenedioxyamphetamine; Prefrontal Cortex; Rats; Rats, Wistar; Receptors, Serotonin; Selective Serotonin Reuptake Inhibitors; Serotonin Agents; Serotonin Receptor Agonists

1998
MDMA stimulus generalization to the 5-HT(1A) serotonin agonist 8-hydroxy-2- (di-n-propylamino)tetralin.
    Pharmacology, biochemistry, and behavior, 2000, Volume: 66, Issue:3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Drug Interactions; Male; N-Methyl-3,4-methylenedioxyamphetamine; Piperazines; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Antagonists; Serotonin Receptor Agonists

2000
Effect of the repeated administration of (+/-)-3,4-methylenedioxymethamphetamine on the behavioral response of rats to the 5-HT1A receptor agonist (+/-)-8-hydroxy-(di-n-propylamino)tetralin.
    Neuropsychobiology, 2001, Volume: 43, Issue:1

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Arousal; Brain; Female; Injections, Subcutaneous; Motor Activity; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Stereotyped Behavior

2001
MDMA and fenfluramine alter the response of the circadian clock to a serotonin agonist in vitro.
    Brain research, 2001, Nov-30, Volume: 920, Issue:1-2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Circadian Rhythm; Drug Interactions; Electrophysiology; Fenfluramine; Hallucinogens; In Vitro Techniques; Male; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Rats, Wistar; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Selective Serotonin Reuptake Inhibitors; Serotonin Receptor Agonists

2001
MDMA alters the response of the circadian clock to a photic and non-photic stimulus.
    Brain research, 2002, Nov-22, Volume: 956, Issue:1

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Biological Clocks; Circadian Rhythm; Cricetinae; Male; Mesocricetus; N-Methyl-3,4-methylenedioxyamphetamine; Photic Stimulation; Raphe Nuclei; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Agents; Serotonin Receptor Agonists; Suprachiasmatic Nucleus

2002
The role of 5-HT in the impairment of thermoregulation observed in rats administered MDMA ('ecstasy') when housed at high ambient temperature.
    Psychopharmacology, 2005, Volume: 179, Issue:4

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Biogenic Monoamines; Body Temperature Regulation; Brain Chemistry; Fenclonine; Fever; Hot Temperature; Housing, Animal; Male; Methysergide; N-Methyl-3,4-methylenedioxyamphetamine; Piperazines; Pyridines; Rats; Serotonin; Serotonin Agents; Serotonin Antagonists; Serotonin Receptor Agonists

2005
Repeated adolescent 3,4-methylenedioxymethamphetamine (MDMA) exposure in rats attenuates the effects of a subsequent challenge with MDMA or a 5-hydroxytryptamine(1A) receptor agonist.
    The Journal of pharmacology and experimental therapeutics, 2006, Volume: 317, Issue:2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aging; Animals; Behavior, Animal; Body Weight; Dose-Response Relationship, Drug; Male; Motor Activity; N-Methyl-3,4-methylenedioxyamphetamine; Neurotoxicity Syndromes; Piperazines; Pyridines; Rats; Rats, Sprague-Dawley; Serotonin 5-HT1 Receptor Agonists

2006
Effect of a serotonin depleting regimen of 3,4-methylenedioxymethamphetamine (MDMA) on the subsequent stimulation of acetylcholine release in the rat prefrontal cortex.
    Brain research bulletin, 2006, Apr-28, Volume: 69, Issue:4

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Acetylcholine; Animals; Male; Microdialysis; N-Methyl-3,4-methylenedioxyamphetamine; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Serotonin; Serotonin Agents; Serotonin Receptor Agonists; Stress, Psychological

2006
N-Methyl-1-(4-methoxyphenyl)-2-aminopropane (PMMA) and N-Methyl-1-(3,4-methylenedioxyphenyl)-2-aminopropane (MDMA) produce non-identical discriminative stimuli in rats.
    Pharmacology, biochemistry, and behavior, 2007, Volume: 86, Issue:3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Cocaine; Discrimination, Psychological; Illicit Drugs; Male; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Rats, Sprague-Dawley; Stereoisomerism; Structure-Activity Relationship

2007
A role for oxytocin and 5-HT(1A) receptors in the prosocial effects of 3,4 methylenedioxymethamphetamine ("ecstasy").
    Neuroscience, 2007, May-11, Volume: 146, Issue:2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Behavior, Animal; Drug Interactions; Enzyme Inhibitors; Hallucinogens; Male; N-Methyl-3,4-methylenedioxyamphetamine; Oxytocin; Piperazines; Proto-Oncogene Proteins c-fos; Pyridines; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT1A; Serotonin Antagonists; Serotonin Receptor Agonists; Social Behavior

2007
Short-term effects of 3,4-methylen-dioxy-metamphetamine (MDMA) on 5-HT(1A) receptors in the rat hippocampus.
    Neurochemistry international, 2007, Volume: 51, Issue:8

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Amphetamine; Animals; Binding Sites; Binding, Competitive; Brain Chemistry; Dopamine Agents; Guanosine 5'-O-(3-Thiotriphosphate); Hippocampus; N-Methyl-3,4-methylenedioxyamphetamine; Radioligand Assay; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT1A; Serotonin; Serotonin Agents; Serotonin Plasma Membrane Transport Proteins; Synaptic Transmission; Time Factors

2007
3,4-Methylenedioxymethamphetamine- and 8-hydroxy-2-di-n-propylamino-tetralin-induced hypothermia: role and location of 5-hydroxytryptamine 1A receptors.
    The Journal of pharmacology and experimental therapeutics, 2007, Volume: 323, Issue:2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Blood Pressure; Body Temperature; Dose-Response Relationship, Drug; Heart Rate; Male; Motor Activity; N-Methyl-3,4-methylenedioxyamphetamine; Piperazines; Pyridines; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1A

2007
Reduced sensitivity to MDMA-induced facilitation of social behaviour in MDMA pre-exposed rats.
    Progress in neuro-psychopharmacology & biological psychiatry, 2008, May-15, Volume: 32, Issue:4

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic Uptake Inhibitors; Animals; Body Temperature; Brain Chemistry; Chromatography, High Pressure Liquid; Male; N-Methyl-3,4-methylenedioxyamphetamine; Piperazines; Pyridines; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT1A; Serotonin Antagonists; Serotonin Receptor Agonists; Social Behavior

2008
Differential long-term effects of MDMA on the serotoninergic system and hippocampal cell proliferation in 5-HTT knock-out vs. wild-type mice.
    The international journal of neuropsychopharmacology, 2008, Volume: 11, Issue:8

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Cell Proliferation; Citalopram; Electrophysiology; Female; Hallucinogens; Hindlimb Suspension; Hippocampus; Injections, Intraperitoneal; Male; Membranes; Mice; Mice, Inbred C57BL; Mice, Knockout; N-Methyl-3,4-methylenedioxyamphetamine; Patch-Clamp Techniques; Raphe Nuclei; Receptor, Serotonin, 5-HT2A; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Agents; Serotonin Plasma Membrane Transport Proteins; Serotonin Receptor Agonists; Swimming

2008
Effect of 8-hydroxy-2-(N,N-di-n-propylamino)tetralin and MDMA on the discriminative stimulus effects of the classical hallucinogen DOM in rats.
    Pharmacology, biochemistry, and behavior, 2009, Volume: 91, Issue:3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Discrimination Learning; Discrimination, Psychological; DOM 2,5-Dimethoxy-4-Methylamphetamine; Dose-Response Relationship, Drug; Drug Synergism; Generalization, Stimulus; Hallucinogens; Isomerism; Male; N-Methyl-3,4-methylenedioxyamphetamine; Piperazines; Rats; Rats, Sprague-Dawley; Serotonin Antagonists; Serotonin Receptor Agonists

2009
50-kHz calls in rats: effects of MDMA and the 5-HT(1A) receptor agonist 8-OH-DPAT.
    Pharmacology, biochemistry, and behavior, 2012, Volume: 101, Issue:2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Dose-Response Relationship, Drug; Male; Motor Activity; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT1A; Serotonin 5-HT1 Receptor Agonists; Vocalization, Animal

2012
Effects of repeated exposure to MDMA on 5HT1a autoreceptor function: behavioral and neurochemical responses to 8-OHDPAT.
    Psychopharmacology, 2013, Volume: 227, Issue:2

    Topics: 5-Hydroxytryptophan; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Autoreceptors; Behavior, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Male; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1A; Serotonin; Serotonin Receptor Agonists; Tryptophan Hydroxylase

2013
Schizophrenia-like disruptions of sensory gating by serotonin receptor stimulation in rats: effect of MDMA, DOI and 8-OH-DPAT.
    Pharmacology, biochemistry, and behavior, 2013, Volume: 112

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Evoked Potentials; Male; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Schizophrenia; Sensory Gating

2013
MDMA self-administration fails to alter the behavioral response to 5-HT(1A) and 5-HT(1B) agonists.
    Psychopharmacology, 2016, Volume: 233, Issue:7

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Behavior, Animal; Indoles; Male; Motor Activity; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Rats, Sprague-Dawley; Serotonin Receptor Agonists

2016
Serotonin antagonists fail to alter MDMA self-administration in rats.
    Pharmacology, biochemistry, and behavior, 2016, Volume: 148

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Drug-Seeking Behavior; Extinction, Psychological; Ketanserin; Male; N-Methyl-3,4-methylenedioxyamphetamine; Oxadiazoles; Piperazines; Pyridines; Rats; Rats, Sprague-Dawley; Self Administration; Serotonin Antagonists

2016
Neurotoxic Effects of 5-MeO-DIPT: A Psychoactive Tryptamine Derivative in Rats.
    Neurotoxicity research, 2016, Volume: 30, Issue:4

    Topics: 5-Methoxytryptamine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Analysis of Variance; Animals; Corpus Striatum; DNA Damage; Dopamine; Frontal Lobe; Glutamic Acid; Hallucinogens; Illicit Drugs; Male; Microdialysis; Motor Activity; N-Methyl-3,4-methylenedioxyamphetamine; Nucleus Accumbens; Oxidative Stress; Rats, Wistar; Serotonin

2016