Compounds > 8-hydroxy-2-(di-n-propylamino)tetralin

8-hydroxy-2-(di-n-propylamino)tetralin and n-(2-(4-(2-methoxyphenyl)-1-piperazinyl)ethyl)-n-(2-pyridinyl)cyclohexanecarboxamide

8-hydroxy-2-(di-n-propylamino)tetralin has been researched along with n-(2-(4-(2-methoxyphenyl)-1-piperazinyl)ethyl)-n-(2-pyridinyl)cyclohexanecarboxamide in 10 studies

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (20.00)18.2507
2000's3 (30.00)29.6817
2010's3 (30.00)24.3611
2020's2 (20.00)2.80

Authors

AuthorsStudies
Chaput, C; Millan, MJ; Newman-Tancredi, A; Verrièle, L1
Audinot, V; Chaput, C; Conte, C; Gavaudan, S; Millan, MJ; Newman-Tancredi, A; Touzard, M; Verrièle, L1
Bartoszyk, GD; Böttcher, H; de Boer, P; Greiner, HE; Harting, J; Liao, Y; Mensonides-Harsema, MM; Wikström, HV1
Bugno, R; Chojnacka-Wójcik, E; Duszyńska, B; Lenda, T; Nikiforuk, A; Paluchowska, MH; Tatarczyńska, E1
Eddershaw, PJ; Gordon, LJ; Lovell, PJ; Moore, SH; Scott, CM; Smith, PW; Starr, KR; Thewlis, KM; Ward, SE; Watson, JM1
Baraldi, A; Brasili, L; Buccioni, M; Cichero, E; Cilia, A; Fossa, P; Franchini, S; Marucci, G; Pirona, L; Prandi, A; Sorbi, C; Tait, A1
Andres-Mach, M; Bączek, T; Belka, M; Czuczwar, SJ; Gomółka, AE; Herold, F; Jastrzębska-Więsek, M; Nowak, G; Partyka, A; Siwek, A; Stefanowicz, J; Słowiński, T; Turło, J; Ulenberg, S; Wesołowska, A; Wróbel, MZ; Zagaja, M; Żołnierek, M; Łuszczki, JJ1
Bączek, T; Belka, M; Bojarski, A; Herold, F; Kleps, J; Kozioł, AE; Król, M; Nowak, G; Siwek, A; Ślifirski, G; Stachowicz, K; Szewczyk, B; Turło, J; Ulenberg, S1
Berthold, EC; Canal, CE; Chen, Y; Gamez-Jimenez, LR; Hampson, AJ; Hiranita, T; Kamble, SH; King, TI; León, F; Lopera-Londoño, C; McCurdy, CR; McMahon, LR; Mottinelli, M; Obeng, S; Patel, A; Restrepo, LF; Sharma, A1
Chen, Z; Collier, T; Fu, H; Liang, SH; Rong, J; Zhou, J1

Reviews

1 review(s) available for 8-hydroxy-2-(di-n-propylamino)tetralin and n-(2-(4-(2-methoxyphenyl)-1-piperazinyl)ethyl)-n-(2-pyridinyl)cyclohexanecarboxamide

ArticleYear
Positron Emission Tomography (PET) Imaging Tracers for Serotonin Receptors.
    Journal of medicinal chemistry, 2022, 08-25, Volume: 65, Issue:16

    Topics: Brain; Humans; Ligands; Positron-Emission Tomography; Radiopharmaceuticals; Receptors, Serotonin

2022

Other Studies

9 other study(ies) available for 8-hydroxy-2-(di-n-propylamino)tetralin and n-(2-(4-(2-methoxyphenyl)-1-piperazinyl)ethyl)-n-(2-pyridinyl)cyclohexanecarboxamide

ArticleYear
Labelling of recombinant human and native rat serotonin 5-HT1A receptors by a novel, selective radioligand, [3H]-S 15535: definition of its binding profile using agonists, antagonists and inverse agonists.
    Naunyn-Schmiedeberg's archives of pharmacology, 1998, Volume: 357, Issue:3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Affinity Labels; Animals; Binding, Competitive; CHO Cells; Cricetinae; Guanine Nucleotides; Hippocampus; Humans; Male; Membranes; Piperazines; Radiopharmaceuticals; Rats; Rats, Wistar; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Receptor Agonists

1998
Agonist and antagonist actions of antipsychotic agents at 5-HT1A receptors: a [35S]GTPgammaS binding study.
    European journal of pharmacology, 1998, Aug-21, Volume: 355, Issue:2-3

    Topics: Animals; Antipsychotic Agents; CHO Cells; Cricetinae; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Agents; Sulfur Radioisotopes

1998
Synthesis and in vitro and in vivo functional studies of ortho-substituted phenylpiperazine and N-substituted 4-N-(o-methoxyphenyl)aminopiperidine analogues of WAY100635.
    Journal of medicinal chemistry, 2000, Feb-10, Volume: 43, Issue:3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aminopyridines; Animals; Frontal Lobe; Guinea Pigs; Hypothermia; Ileum; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; Piperazines; Pyridines; Radioligand Assay; Rats; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Antagonists; Serotonin Receptor Agonists; Structure-Activity Relationship; Ultrasonics; Vocalization, Animal

2000
The influence of modifications in imide fragment structure on 5-HT(1A) and 5-HT(7) receptor affinity and in vivo pharmacological properties of some new 1-(m-trifluoromethylphenyl)piperazines.
    Bioorganic & medicinal chemistry, 2007, Nov-15, Volume: 15, Issue:22

    Topics: Animals; Body Temperature; Cell Line; Cells, Cultured; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Humans; Imides; Ligands; Lip; Maze Learning; Mice; Molecular Structure; Motor Activity; Piperazines; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT1A; Receptors, Serotonin; Stereoisomerism; Structure-Activity Relationship; Swimming

2007
Discovery of potent, orally bioavailable, selective 5-HT1A/B/D receptor antagonists.
    Journal of medicinal chemistry, 2008, May-22, Volume: 51, Issue:10

    Topics: Animals; Blood-Brain Barrier; Cerebral Cortex; Humans; In Vitro Techniques; Piperazines; Quinolines; Radioligand Assay; Rats; Recombinant Proteins; Serotonin 5-HT1 Receptor Antagonists; Structure-Activity Relationship

2008
1,3-Dioxolane-based ligands incorporating a lactam or imide moiety: structure-affinity/activity relationship at alpha1-adrenoceptor subtypes and at 5-HT1A receptors.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:9

    Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-1 Receptor Antagonists; Animals; Dioxolanes; Humans; Imides; Lactams; Ligands; Male; Models, Molecular; Protein Binding; Protein Conformation; Rats; Receptor, Serotonin, 5-HT1A; Receptors, Adrenergic, alpha-1; Serotonin 5-HT1 Receptor Agonists; Serotonin 5-HT1 Receptor Antagonists; Stereoisomerism; Structure-Activity Relationship; Substrate Specificity

2010
Synthesis and biological investigation of new equatorial (β) stereoisomers of 3-aminotropane arylamides with atypical antipsychotic profile.
    Bioorganic & medicinal chemistry, 2016, 09-15, Volume: 24, Issue:18

    Topics: Animals; Antipsychotic Agents; Benzene Derivatives; Dopamine D2 Receptor Antagonists; Male; Mice; Rats, Wistar; Receptor, Serotonin, 5-HT1A; Receptor, Serotonin, 5-HT2A; Receptors, Dopamine D2; Serotonin 5-HT2 Receptor Antagonists; Stereoisomerism; Structure-Activity Relationship; Tropanes

2016
Synthesis of novel pyrido[1,2-c]pyrimidine derivatives with rigidized tryptamine moiety as potential SSRI and 5-HT
    European journal of medicinal chemistry, 2019, Mar-15, Volume: 166

    Topics: Animals; Chemistry Techniques, Synthetic; Drug Design; Ligands; Mice; Pyrimidines; Receptor, Serotonin, 5-HT1A; Selective Serotonin Reuptake Inhibitors; Structure-Activity Relationship; Tryptamines

2019
Activity of
    Journal of medicinal chemistry, 2021, 09-23, Volume: 64, Issue:18

    Topics: Analgesics; Animals; Behavior, Animal; Female; HEK293 Cells; Humans; Male; Nociceptive Pain; Rats, Sprague-Dawley; Receptors, Serotonin; Secologanin Tryptamine Alkaloids

2021