8-hydroxy-2-(di-n-propylamino)tetralin and muscimol

8-hydroxy-2-(di-n-propylamino)tetralin has been researched along with muscimol in 28 studies

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-19901 (3.57)18.7374
1990's7 (25.00)18.2507
2000's8 (28.57)29.6817
2010's11 (39.29)24.3611
2020's1 (3.57)2.80

Authors

AuthorsStudies
Bartoccini, F; Carminati, P; Castorina, M; Di Cesare, MA; Di Serio, S; Gallo, G; Ghirardi, O; Giorgi, F; Giorgi, L; Minetti, P; Piersanti, G; Tarzia, G; Tinti, MO1
McBride, WJ; Yoshimoto, K1
Shibata, S; Tominaga, K; Ueki, S; Watanabe, S1
Bradbury, AJ; Higgins, GA; Jones, BJ; Oakley, NR1
Kelder, D; Ross, SB1
al-Dahan, MI; Jalilian Tehrani, MH; Thalmann, RH1
Fletcher, PJ1
Bouysset, F; Laubie, M; Vayssettes-Courchay, C; Verbeuren, TJ1
Javaid, J; Shim, I; Wirtshafter, D1
Crochet, S; Sakai, K2
Andrade, TG; Bueno, C; Pobbe, RL; Sena, LM; Viana, MB; Zangrossi, H1
Guptarak, J; Selvamani, A; Uphouse, L1
de Andrade, TG; Dos Santos, L; Zangrossi, H1
Fletcher, PJ; Funk, D; Lê, AD; Li, Z1
Forsberg, T; Gabrielsson, J; Martinsson, S; Pozarek, S; Ross, SB; Visser, SA1
Francl, JM; Glass, JD; Guinn, J; Kaur, G1
Congleton, MR; Duncan, MJ1
Morrison, SF; Nakamura, K1
Brown, J; Cockburn, C; Nowell, K; Pham-Le, NM1
Ferreira, MD; Menescal-de-Oliveira, L1
Chang, SD; Liang, KC1
Ha, RR; Hong, SI; Jang, CG; Jung, YH; Kim, SY; Kwon, SH; Lee, KH; Lee, SY1
Albrechet-Souza, L; Almada, RC; Brandão, ML1
Almada, RC; Brandão, ML; Coimbra, NC1
Atzori, M; Dinh, L; Galindo-Charles, L; García-Oscos, F; Pérez Padilla, EA; Pineda, JC; Salgado, H; Torres-Ramírez, O1
Jafari-Sabet, M; Nemati, S; Torab, M1
da Silva, GSF; Gargaglioni, LH; Leirão, IP; Zoccal, DB1

Other Studies

28 other study(ies) available for 8-hydroxy-2-(di-n-propylamino)tetralin and muscimol

ArticleYear
2-n-Butyl-9-methyl-8-[1,2,3]triazol-2-yl-9H-purin-6-ylamine and analogues as A2A adenosine receptor antagonists. Design, synthesis, and pharmacological characterization.
    Journal of medicinal chemistry, 2005, Nov-03, Volume: 48, Issue:22

    Topics: Adenine; Adenosine A2 Receptor Antagonists; Animals; Cell Line; Cricetinae; Cricetulus; Drug Design; Humans; Imidazoles; Male; Models, Molecular; Motor Activity; Purines; Radioligand Assay; Rats; Rats, Inbred F344; Structure-Activity Relationship; Triazoles

2005
Regulation of nucleus accumbens dopamine release by the dorsal raphe nucleus in the rat.
    Neurochemical research, 1992, Volume: 17, Issue:5

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Dopamine; Glutamates; Glutamic Acid; Male; Muscimol; Nucleus Accumbens; Raphe Nuclei; Rats; Rats, Inbred Strains; Serotonin; Tetrahydronaphthalenes

1992
Effects of inhibitory and excitatory drugs on the metabolic rhythm of the hamster suprachiasmatic nucleus in vitro.
    European journal of pharmacology, 1992, Jun-24, Volume: 217, Issue:1

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Circadian Rhythm; Cricetinae; Deoxyglucose; Dose-Response Relationship, Drug; Flurazepam; Glutamates; Glutamic Acid; Male; Mesocricetus; Muscimol; Neurons; Pentobarbital; Potassium Chloride; Suprachiasmatic Nucleus; Tetrodotoxin

1992
Behavioural and biochemical consequences following activation of 5HT1-like and GABA receptors in the dorsal raphé nucleus of the rat.
    Neuropharmacology, 1988, Volume: 27, Issue:10

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Anti-Anxiety Agents; Avoidance Learning; Body Temperature; Brain; Buspirone; Hydroxyindoleacetic Acid; Male; Muscimol; Posture; Pyrimidines; Raphe Nuclei; Rats; Rats, Inbred Strains; Receptors, GABA-A; Receptors, Serotonin; Social Behavior; Tetrahydronaphthalenes; Tissue Distribution

1988
Counteraction of the rapid tolerance to 8-OH-DPAT-induced corticosterone secretion in rats by activation of the GABAA receptor-chloride channel complex.
    British journal of pharmacology, 1993, Volume: 109, Issue:1

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Benzodiazepines; Bicuculline; Chloride Channels; Chlormethiazole; Corticosterone; Drug Tolerance; Ion Channels; Male; Membrane Proteins; Muscimol; Pentobarbital; Picrotoxin; Rats; Rats, Sprague-Dawley; Receptors, GABA-A

1993
Regulation of gamma-aminobutyric acidB (GABAB) receptors in cerebral cortex during the estrous cycle.
    Brain research, 1994, Mar-21, Volume: 640, Issue:1-2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Baclofen; Brain Chemistry; Cerebral Cortex; Estrus; Female; In Vitro Techniques; Ligands; Membranes; Muscimol; Rats; Rats, Sprague-Dawley; Receptors, GABA-B

1994
A comparison of the effects of dorsal or median raphe injections of 8-OH-DPAT in three operant tasks measuring response inhibition.
    Behavioural brain research, 1993, Apr-30, Volume: 54, Issue:2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Brain Mapping; Conditioning, Operant; Dose-Response Relationship, Drug; Extinction, Psychological; Male; Motor Activity; Muscimol; Neural Inhibition; Neurons; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Reinforcement Schedule; Serotonin

1993
Evidence against the involvement of the nucleus tractus solitarii in the sympatholytic effect of 8-hydroxy-2-(di-n-propylamino)tetralin in the cat.
    European journal of pharmacology, 1995, Oct-24, Volume: 285, Issue:3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Blood Pressure; Cats; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; GABA Agonists; Heart Rate; Kainic Acid; Kynurenic Acid; Male; Microinjections; Muscimol; Serotonin Receptor Agonists; Solitary Nucleus; Sympatholytics; Synaptic Transmission; Tegmentum Mesencephali

1995
Dissociation of hippocampal serotonin release and locomotor activity following pharmacological manipulations of the median raphe nucleus.
    Behavioural brain research, 1997, Volume: 89, Issue:1-2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Baclofen; Extracellular Space; GABA Agonists; Hippocampus; Hydroxyindoleacetic Acid; Male; Microdialysis; Motor Activity; Muscimol; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Serotonin; Serotonin Receptor Agonists

1997
Role of dorsal raphe neurons in paradoxical sleep generation in the cat: no evidence for a serotonergic mechanism.
    The European journal of neuroscience, 2001, Volume: 13, Issue:1

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Bicuculline; Cats; Excitatory Amino Acid Agonists; Female; GABA Agonists; GABA Antagonists; Kainic Acid; Male; Microdialysis; Muscimol; Neurons; Piperazines; Pyridines; Raphe Nuclei; Serotonin; Serotonin Antagonists; Sleep Stages; Sleep, REM; Wakefulness

2001
Increase in antidromic excitability in presumed serotonergic dorsal raphe neurons during paradoxical sleep in the cat.
    Brain research, 2001, Apr-20, Volume: 898, Issue:2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Cats; Evoked Potentials; Female; GABA Agonists; Male; Membrane Potentials; Mesencephalon; Methoxydimethyltryptamines; Muscimol; Neural Pathways; Neurons; Raphe Nuclei; Reaction Time; Serotonin; Serotonin Receptor Agonists; Sleep, REM

2001
The dorsal raphe nucleus exerts opposed control on generalized anxiety and panic-related defensive responses in rats.
    Behavioural brain research, 2003, Jun-16, Volume: 142, Issue:1-2

    Topics: 5,7-Dihydroxytryptamine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Anxiety; Avoidance Learning; Carbolines; Disease Models, Animal; Escape Reaction; GABA Agonists; GABA Antagonists; Male; Muscimol; Neural Pathways; Panic Disorder; Raphe Nuclei; Rats; Rats, Wistar; Serotonin; Serotonin Receptor Agonists

2003
GABAA-5-HT1A receptor interaction in the mediobasal hypothalamus.
    Brain research, 2004, Nov-19, Volume: 1027, Issue:1-2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Behavior, Animal; Bicuculline; Drug Interactions; Estradiol; Female; GABA Agonists; GABA Antagonists; Hypothalamus, Middle; Muscimol; Ovariectomy; Posture; Progesterone; Rats; Rats, Inbred F344; Receptor, Serotonin, 5-HT1A; Receptors, GABA-A; Serotonin Agents; Sexual Behavior, Animal; Time Factors

2004
Serotonergic neurons in the median raphe nucleus regulate inhibitory avoidance but not escape behavior in the rat elevated T-maze test of anxiety.
    Psychopharmacology, 2005, Volume: 179, Issue:4

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Anxiety; Avoidance Learning; Carbolines; Escape Reaction; Excitatory Amino Acid Antagonists; GABA Agonists; Kainic Acid; Male; Motor Activity; Muscimol; Neurons; Piperazines; Pyridines; Raphe Nuclei; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT1A; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists

2005
Effects of injections of 8-hydroxy-2-(di-n-propylamino)tetralin or muscimol in the median raphe nucleus on c-fos mRNA in the rat brain.
    Neuroscience, 2005, Volume: 131, Issue:2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Brain; Genes, fos; Injections, Intraventricular; Male; Muscimol; Raphe Nuclei; Rats; Rats, Wistar; RNA, Messenger

2005
Rapid and long-lasting tolerance to clomethiazole-induced hypothermia in the rat.
    European journal of pharmacology, 2005, Apr-11, Volume: 512, Issue:2-3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Bicuculline; Body Temperature; Chlormethiazole; Dizocilpine Maleate; Drug Tolerance; Excitatory Amino Acid Antagonists; GABA Agonists; GABA Antagonists; GABA Modulators; Hypothermia; Injections, Subcutaneous; Male; Muscimol; Picrotoxin; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Serotonin 5-HT1 Receptor Agonists; Serotonin Receptor Agonists; Time Factors

2005
On the intrinsic regulation of neuropeptide Y release in the mammalian suprachiasmatic nucleus circadian clock.
    The European journal of neuroscience, 2010, Volume: 31, Issue:6

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Circadian Rhythm; Cricetinae; Electric Stimulation; GABA Agonists; Male; Metergoline; Microdialysis; Motor Activity; Muscimol; Neuropeptide Y; Physical Conditioning, Animal; Radioimmunoassay; Serotonin Antagonists; Serotonin Receptor Agonists; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Suprachiasmatic Nucleus

2010
Neural mechanisms mediating circadian phase resetting by activation of 5-HT(7) receptors in the dorsal raphe: roles of GABAergic and glutamatergic neurotransmission.
    Brain research, 2010, Dec-17, Volume: 1366

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Bicuculline; Circadian Rhythm; Cricetinae; Dizocilpine Maleate; Drug Administration Schedule; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Male; Mesocricetus; Microinjections; Muscimol; N-Methylaspartate; Raphe Nuclei; Receptors, Serotonin; Serotonin Receptor Agonists; Synaptic Transmission

2010
Central efferent pathways for cold-defensive and febrile shivering.
    The Journal of physiology, 2011, Jul-15, Volume: 589, Issue:Pt 14

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adipose Tissue, Brown; Animals; Blood Pressure; Body Temperature Regulation; Cold Temperature; Dinoprostone; Efferent Pathways; Fever; GABA-A Receptor Antagonists; Heart Rate; Male; Mediodorsal Thalamic Nucleus; Medulla Oblongata; Muscimol; N-Methylaspartate; Neural Pathways; Neurons; Preoptic Area; Raphe Nuclei; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT1A; Receptors, GABA-A; Shivering; Skin Temperature; Sympathetic Nervous System; Tachycardia; Thermogenesis

2011
Activation of GABAA or 5HT1A receptors in the raphé pallidus abolish the cardiovascular responses to exogenous stress in conscious rats.
    Brain research bulletin, 2011, Nov-25, Volume: 86, Issue:5-6

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Blood Pressure; GABA-A Receptor Agonists; Heart Rate; Male; Microinjections; Muscimol; Random Allocation; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1A; Receptors, GABA-A; Serotonin; Stress, Physiological; Stress, Psychological; Telemetry

2011
Opioidergic, GABAergic and serotonergic neurotransmission in the dorsal raphe nucleus modulates tonic immobility in guinea pigs.
    Physiology & behavior, 2012, May-15, Volume: 106, Issue:2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Analgesics, Opioid; Animals; Bicuculline; Drug Interactions; GABAergic Neurons; Guinea Pigs; Immobility Response, Tonic; Male; Microinjections; Morphine; Muscimol; Naloxone; Opioid Peptides; Raphe Nuclei; Serotonergic Neurons; Serotonin; Serotonin 5-HT2 Receptor Agonists; Synaptic Transmission

2012
Roles of hippocampal GABA(A) and muscarinic receptors in consolidation of context memory and context-shock association in contextual fear conditioning: a double dissociation study.
    Neurobiology of learning and memory, 2012, Volume: 98, Issue:1

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Association Learning; Conditioning, Psychological; Electroshock; Excitatory Amino Acid Antagonists; Fear; GABA-A Receptor Agonists; Hippocampus; Male; Memory; Muscarinic Antagonists; Muscimol; Rats; Rats, Wistar; Receptors, GABA-A; Receptors, Muscarinic; Scopolamine; Serotonin Receptor Agonists; Valine

2012
Anxiolytic effects of Julibroside C1 isolated from Albizzia julibrissin in mice.
    Progress in neuro-psychopharmacology & biological psychiatry, 2013, Jul-01, Volume: 44

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Albizzia; Analysis of Variance; Animals; Anti-Anxiety Agents; Autoradiography; Brain; Dose-Response Relationship, Drug; Flunitrazepam; Male; Maze Learning; Mice; Mice, Inbred ICR; Motor Activity; Muscimol; Plant Preparations; Protein Binding; Radionuclide Imaging; Saponins; Triterpenes; Tritium

2013
Further evidence for involvement of the dorsal hippocampus serotonergic and γ-aminobutyric acid (GABA)ergic pathways in the expression of contextual fear conditioning in rats.
    Journal of psychopharmacology (Oxford, England), 2013, Volume: 27, Issue:12

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Behavior, Animal; Brain; Conditioning, Psychological; Fear; Freezing Reaction, Cataleptic; gamma-Aminobutyric Acid; Hippocampus; Male; Muscimol; Prefrontal Cortex; Rats; Rats, Wistar; Reflex, Startle; Serotonin; Serotonin Receptor Agonists; Time Factors

2013
Medial prefrontal cortex serotonergic and GABAergic mechanisms modulate the expression of contextual fear: intratelencephalic pathways and differential involvement of cortical subregions.
    Neuroscience, 2015, Jan-22, Volume: 284

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Biotin; Conditioning, Psychological; Dextrans; Fear; Freezing Reaction, Cataleptic; GABA-A Receptor Agonists; gamma-Aminobutyric Acid; Limbic Lobe; Male; Muscimol; Neural Pathways; Neuroanatomical Tract-Tracing Techniques; Neuronal Tract-Tracers; Prefrontal Cortex; Rats, Wistar; Receptor, Serotonin, 5-HT1A; Receptors, GABA-A; Reflex, Startle; Serotonin; Serotonin 5-HT1 Receptor Agonists

2015
Activation of 5-HT receptors inhibits GABAergic transmission by pre-and post-synaptic mechanisms in layer II/III of the juvenile rat auditory cortex.
    Synapse (New York, N.Y.), 2015, Volume: 69, Issue:3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Auditory Cortex; GABA Agonists; GABAergic Neurons; Inhibitory Postsynaptic Potentials; Miniature Postsynaptic Potentials; Muscimol; Piperazines; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Ritanserin; Serotonin Receptor Agonists; Synapses

2015
Cross state-dependency of learning between 5-HT1A and/or 5-HT7 receptor agonists and muscimol in the mouse dorsal hippocampus.
    Journal of psychopharmacology (Oxford, England), 2019, Volume: 33, Issue:6

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amnesia; Animals; Avoidance Learning; CA1 Region, Hippocampal; Conditioning, Classical; GABA-A Receptor Agonists; Male; Memory; Mice; Microinjections; Muscimol; Receptor, Serotonin, 5-HT1A; Receptors, Serotonin; Serotonin Receptor Agonists

2019
Differential modulation of active expiration during hypercapnia by the medullary raphe in unanesthetized rats.
    Pflugers Archiv : European journal of physiology, 2020, Volume: 472, Issue:11

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Abdominal Muscles; Animals; Diaphragm; Exhalation; GABA-A Receptor Agonists; Hypercapnia; Male; Muscimol; Muscle Contraction; Raphe Nuclei; Rats; Rats, Wistar; Serotonin Receptor Agonists; Sleep; Wakefulness

2020