8-hydroxy-2-(di-n-propylamino)tetralin has been researched along with morphine in 30 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (6.67) | 18.7374 |
| 1990's | 13 (43.33) | 18.2507 |
| 2000's | 10 (33.33) | 29.6817 |
| 2010's | 5 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Flores, CM; Hornby, PJ; Hulihan-Giblin, BA; Kellar, KJ; Lumpkin, MD | 1 |
| Colpaert, FC; Millan, MJ | 1 |
| Dzoljic, MR; Kaplan, CD; Saxena, PR; v Ent, M | 1 |
| Bhargava, HN; Gulati, A | 1 |
| Berendsen, HH; Broekkamp, CL; Oosterloo, SK; van Delft, AM | 1 |
| Berge, OG; Fasmer, OB; Hole, K; Ogren, SO | 1 |
| Alhaider, AA; Wilcox, GL | 1 |
| Cancela, LM; Keller, EA; Molina, VA; Orsingher, OA | 1 |
| Morgan, D; Picker, MJ | 1 |
| Lin, Q; Peng, YB; Willis, WD | 1 |
| Cox, BM; Noble, F | 1 |
| Andrews, P; Matsuki, N; Saito, H; Torii, Y | 1 |
| Dykstra, LA; Powell, KR | 1 |
| Meltzer, HY; Willins, DL | 1 |
| Belknap, JK; Hain, HS; Mogil, JS | 1 |
| Ferreira, M; Gillis, RA; Sahibzada, N; Taveira-DaSilva, AM; Wasserman, AM | 1 |
| Andrews, PL; Hagiwara, H; Kakaimoto, S; Matsuki, N; Okada, F; Toyoda, M; Woods, AJ | 1 |
| Esteban, S; García-Sevilla, JA; Sastre-Coll, A | 1 |
| Cervo, L; De Deurwaerdère, P; Spampinato, U; Stinus, L | 1 |
| Borszcz, GS; Munn, EM | 1 |
| Mogil, JS; Nemmani, KV | 1 |
| Bland, ST; Der-Avakian, A; Grahn, RE; Hammack, SE; Maier, SF; Pepin, JL; Sparks, PD; Watkins, LR; Will, MJ | 1 |
| Bardin, L; Colpaert, FC | 1 |
| Charkhpour, M; Nayebi, AR | 1 |
| Dutschmann, M; Guenther, U; Hoeft, A; Manzke, T; Putensen, C; Wrigge, H; Zinserling, J | 1 |
| Charkhpour, M; Doustar, Y; Hassanzadeh, K; Nayebi, AR | 1 |
| Goeldner, C; Kieffer, BL; Lutz, PE; Pradhan, AA | 1 |
| Ferreira, MD; Menescal-de-Oliveira, L | 1 |
| Haji, A; Kimura, S; Ohi, Y | 1 |
| Bastian, G; Bourgoin, S; Hamon, M; Kayser, V; Michot, B | 1 |
30 other study(ies) available for 8-hydroxy-2-(di-n-propylamino)tetralin and morphine
| Article | Year |
|---|---|
Partial characterization of a neurotransmitter pathway regulating the in vivo release of prolactin.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Bromocriptine; Haloperidol; Male; Mecamylamine; Methysergide; Morphine; Naltrexone; Narcotic Antagonists; Neurotransmitter Agents; Nicotine; Nicotinic Antagonists; Pituitary Gland; Prolactin; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Nicotinic; Receptors, Opioid; Receptors, Serotonin; Serotonin Antagonists; Tetrahydronaphthalenes | 1992 |
5-hydroxytryptamine (HT)1A receptors and the tail-flick response. II. High efficacy 5-HT1A agonists attenuate morphine-induced antinociception in mice in a competitive-like manner.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Analgesia; Animals; Dopamine Agents; Dose-Response Relationship, Drug; Drug Interactions; Hot Temperature; Male; Mice; Morphine; Pressure; Receptors, Serotonin; Sympathomimetics; Tetrahydronaphthalenes | 1991 |
Microinjection of 8-OH-DPAT into nucleus accumbens attenuates naloxone-induced morphine withdrawal syndrome.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Male; Microinjections; Morphine; Naloxone; Naphthalenes; Nucleus Accumbens; Rats; Rats, Inbred Strains; Receptors, Serotonin; Septal Nuclei; Substance Withdrawal Syndrome; Tetrahydronaphthalenes | 1990 |
Down-regulation of hypothalamic 5-HT1A receptors in morphine-abstinent rats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Body Temperature; Body Weight; Down-Regulation; Hypothalamus; Kinetics; Male; Membranes; Morphine; Rats; Rats, Inbred Strains; Receptors, Serotonin; Spinal Cord; Substance Withdrawal Syndrome; Tetrahydronaphthalenes | 1990 |
Effect of metergoline, fenfluramine, and 8-OHDPAT on catalepsy induced by haloperidol or morphine.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Catalepsy; Drug Interactions; Fenfluramine; Haloperidol; Male; Metergoline; Mice; Morphine; Rats; Rats, Inbred Strains; Serotonin; Tetrahydronaphthalenes | 1988 |
The putative serotonin receptor agonist 8-hydroxy-2-(di-n-propylamino)tetralin antagonizes the antinociceptive effect of morphine.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Central Nervous System; Male; Mice; Morphine; Naphthalenes; Pain; Receptors, Serotonin; Tetrahydronaphthalenes | 1985 |
Differential roles of 5-hydroxytryptamine1A and 5-hydroxytryptamine1B receptor subtypes in modulating spinal nociceptive transmission in mice.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Behavior, Animal; Buspirone; Male; Mice; Morphine; N-Methylaspartate; Pain; Piperazines; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Spinal Cord; Substance P; Synaptic Transmission | 1993 |
Lack of adaptive changes in 5-HT sites in perinatally undernourished rats after chronic stress: opioid influence.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adaptation, Physiological; Animals; Animals, Newborn; Behavior, Animal; Dietary Proteins; Endorphins; Female; Immobilization; Methoxydimethyltryptamines; Morphine; Naloxone; Nutrition Disorders; Rats; Receptors, Serotonin; Stress, Physiological | 1994 |
Discriminative stimulus effects of the 5HT1A agonist 8-OH-DPAT: attenuation by mu but not by kappa opioids.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; 8-Hydroxy-2-(di-n-propylamino)tetralin; Analgesics; Animals; Benzomorphans; Discrimination Learning; Drug Therapy, Combination; Fentanyl; Male; Morphine; Narcotics; Pyrimidines; Pyrrolidines; Rats; Receptors, Opioid, kappa; Receptors, Opioid, mu; Serotonin Receptor Agonists | 1995 |
Antinociception and inhibition from the periaqueductal gray are mediated in part by spinal 5-hydroxytryptamine(1A) receptors.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Dose-Response Relationship, Drug; Evoked Potentials; Male; Microdialysis; Morphine; Nociceptors; Propranolol; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, Serotonin; Spinal Cord; Time Factors | 1996 |
Differential desensitization of mu- and delta- opioid receptors in selected neural pathways following chronic morphine treatment.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adenylyl Cyclases; Aminobutyrates; Analgesics; Animals; Brain; Caudate Nucleus; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Glutamic Acid; Male; Morphine; Morphine Dependence; Naloxone; Narcotic Antagonists; Nucleus Accumbens; Oligopeptides; Periaqueductal Gray; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Receptors, Opioid, mu; Serotonin Receptor Agonists; Substance Withdrawal Syndrome; Thalamus | 1996 |
The pharmacology of the emetic response to upper gastrointestinal tract stimulation in Suncus murinus.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Digestive System Physiological Phenomena; Diterpenes; Granisetron; Male; Morphine; Motion; Neurokinin-1 Receptor Antagonists; Nicotine; Piperidines; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; Serotonin Antagonists; Serotonin Receptor Agonists; Shrews; Vomiting | 1996 |
The role of serotonergic receptors in the effects of mu opioids in squirrel monkeys responding under a titration procedure.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Analgesics, Opioid; Analysis of Variance; Animals; Behavior, Animal; Dose-Response Relationship, Drug; Electroshock; Male; Morphine; Pain Measurement; Pyrimidines; Receptors, Opioid, mu; Receptors, Serotonin; Saimiri; Serotonin Antagonists; Serotonin Receptor Agonists | 1996 |
Serotonin 5-HT2C agonists selectively inhibit morphine-induced dopamine efflux in the nucleus accumbens.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Cocaine; Dopamine; Dopamine Uptake Inhibitors; Male; Microdialysis; Morphine; Narcotic Antagonists; Nucleus Accumbens; Piperazines; Pyrazines; Rats; Rats, Sprague-Dawley; Serotonin Antagonists; Serotonin Receptor Agonists | 1998 |
Pharmacogenetic evidence for the involvement of 5-hydroxytryptamine (Serotonin)-1B receptors in the mediation of morphine antinociceptive sensitivity.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Analgesics; Animals; Dose-Response Relationship, Drug; Drug Interactions; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Morphine; Oxadiazoles; Piperazines; Receptors, Serotonin; Sensitivity and Specificity; Serotonin Antagonists; Species Specificity; Time Factors | 1999 |
Reversal of morphine-induced apnea in the anesthetized rat by drugs that activate 5-hydroxytryptamine(1A) receptors.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aminopyridines; Animals; Apnea; Buspirone; Diaphragm; Drug Interactions; Electromyography; Male; Morphine; Muscle Contraction; Piperazines; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists | 2000 |
The emetic and anti-emetic effects of the capsaicin analogue resiniferatoxin in Suncus murinus, the house musk shrew.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Abdomen; Animals; Animals, Newborn; Antiemetics; Behavior, Animal; Capsaicin; Cisplatin; Copper Sulfate; Diterpenes; Dose-Response Relationship, Drug; Female; Indoles; Injections, Intraventricular; Male; Medulla Oblongata; Morphine; Motion Sickness; Nicotine; Piperidines; Proto-Oncogene Proteins c-fos; Serotonin Receptor Agonists; Shrews; Tropisetron; Vagotomy; Vomiting | 2000 |
Supersensitivity of 5-HT1A autoreceptors and alpha2-adrenoceptors regulating monoamine synthesis in the brain of morphine-dependent rats.
Topics: 5-Hydroxytryptophan; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Autoreceptors; Biogenic Monoamines; Brain; Dihydroxyphenylalanine; Male; Morphine; Morphine Dependence; Naloxone; Narcotics; Norepinephrine; Piperazines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Receptor Agonists; Substance Withdrawal Syndrome | 2002 |
Central 5-HT(4) receptors and dopamine-dependent motor behaviors: searching for a functional role.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Apomorphine; Catalepsy; Central Nervous System; Dopamine; Dopamine Agonists; Dopamine Antagonists; Haloperidol; Indoles; Injections, Intraventricular; Male; Morphine; Motor Activity; Narcotics; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Receptors, Serotonin, 5-HT4; Serotonin Antagonists; Serotonin Receptor Agonists; Stereotyped Behavior; Sulfonamides | 2002 |
Increases in the release and metabolism of serotonin in nucleus parafascicularis thalami following systemically administered morphine in the rat.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Analgesics, Opioid; Animals; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Electrochemistry; Extracellular Space; Hydroxyindoleacetic Acid; Intralaminar Thalamic Nuclei; Male; Microdialysis; Morphine; Rats; Rats, Long-Evans; Serotonin; Vocalization, Animal | 2002 |
Serotonin-GABA interactions in the modulation of mu- and kappa-opioid analgesia.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; 5,7-Dihydroxytryptamine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Analgesia; Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; Bicuculline; Diazepam; Dose-Response Relationship, Drug; Drug Interactions; Fenclonine; GABA Antagonists; GABA Modulators; gamma-Aminobutyric Acid; Male; Mice; Mice, Inbred Strains; Morphine; Pain Threshold; Reaction Time; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu; Serotonin; Serotonin Agents; Serotonin Antagonists | 2003 |
Electrolytic lesions and pharmacological inhibition of the dorsal raphe nucleus prevent stressor potentiation of morphine conditioned place preference in rats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Behavior, Animal; Conditioning, Operant; Electrolysis; Electroshock; Injections, Subcutaneous; Male; Microinjections; Morphine; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Reward; Serotonin; Serotonin 5-HT1 Receptor Antagonists; Stress, Psychological | 2004 |
Role of spinal 5-HT(1A) receptors in morphine analgesia and tolerance in rats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Afferent Pathways; Analgesics, Opioid; Animals; Dose-Response Relationship, Drug; Drug Interactions; Drug Tolerance; Injections, Spinal; Male; Morphine; Pain; Pain Measurement; Pain Threshold; Piperazines; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1A; Receptors, Opioid; Serotonin Antagonists; Spinal Cord | 2004 |
Role of 5-HT(1A) and 5-HT(2) receptors of dorsal and median raphe nucleus in tolerance to morphine analgesia in rats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Analgesics, Opioid; Animals; Drug Tolerance; Male; Morphine; Raphe Nuclei; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT1A; Receptors, Serotonin, 5-HT2 | 2006 |
The counteraction of opioid-induced ventilatory depression by the serotonin 1A-agonist 8-OH-DPAT does not antagonize antinociception in rats in situ and in vivo.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Analgesics, Opioid; Animals; Dose-Response Relationship, Drug; Fentanyl; Male; Morphine; Nerve Fibers, Unmyelinated; Pain; Pain Measurement; Pain Threshold; Phrenic Nerve; Piperazines; Pulmonary Ventilation; Pyridines; Rats; Rats, Sprague-Dawley; Reaction Time; Reflex; Respiratory Mechanics; Serotonin 5-HT1 Receptor Agonists; Serotonin Antagonists; Serotonin Receptor Agonists | 2009 |
8-OH-DPAT prevents morphine-induced apoptosis in rat dorsal raphe nucleus: a possible mechanism for attenuating morphine tolerance.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Analgesics, Opioid; Animals; Apoptosis; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Tolerance; Hot Temperature; In Situ Nick-End Labeling; Injections, Intraperitoneal; Male; Morphine; Pain; Pain Measurement; Piperazines; Raphe Nuclei; Rats; Rats, Wistar; Serotonin 5-HT1 Receptor Agonists; Serotonin 5-HT1 Receptor Antagonists; Serotonin Antagonists; Serotonin Receptor Agonists; Time Factors | 2010 |
Sequential and opposing alterations of 5-HT(1A) receptor function during withdrawal from chronic morphine.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Autoradiography; Dose-Response Relationship, Drug; Drug Administration Schedule; Guanosine 5'-O-(3-Thiotriphosphate); Male; Mice; Mice, Inbred C57BL; Morphine; Narcotics; Prefrontal Cortex; Protein Binding; Raphe Nuclei; Receptor, Serotonin, 5-HT1A; Serotonin Receptor Agonists; Sulfur Radioisotopes; Time Factors | 2011 |
Opioidergic, GABAergic and serotonergic neurotransmission in the dorsal raphe nucleus modulates tonic immobility in guinea pigs.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Analgesics, Opioid; Animals; Bicuculline; Drug Interactions; GABAergic Neurons; Guinea Pigs; Immobility Response, Tonic; Male; Microinjections; Morphine; Muscimol; Naloxone; Opioid Peptides; Raphe Nuclei; Serotonergic Neurons; Serotonin; Serotonin 5-HT2 Receptor Agonists; Synaptic Transmission | 2012 |
Effects of cholinesterase inhibitors and serotonin-1A receptor agonists on morphine-induced ventilatory depression and antinociception in rats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Analgesia; Animals; Buspirone; Cholinesterase Inhibitors; Donepezil; Indans; Male; Morphine; Pain; Physostigmine; Piperidines; Rats; Rats, Wistar; Respiratory Insufficiency; Serotonin 5-HT1 Receptor Agonists | 2013 |
Differential pharmacological alleviation of oxaliplatin-induced hyperalgesia/allodynia at cephalic versus extra-cephalic level in rodents.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amines; Analgesics; Animals; Cold Temperature; Cyclohexanecarboxylic Acids; Dipeptides; Formaldehyde; Gabapentin; gamma-Aminobutyric Acid; Ganglia, Spinal; Hyperalgesia; Male; Mice; Mice, Inbred C57BL; Morphine; Organoplatinum Compounds; Oxaliplatin; Piperazines; Piperidines; Quinazolines; Rats; Rats, Sprague-Dawley; Spinal Cord; Touch; TRPA1 Cation Channel; TRPC Cation Channels; Tryptamines | 2014 |