Compounds > 8-hydroxy-2-(di-n-propylamino)tetralin

8-hydroxy-2-(di-n-propylamino)tetralin and ipsapirone

8-hydroxy-2-(di-n-propylamino)tetralin has been researched along with ipsapirone in 115 studies

Research

Studies (115)

Timeframe	Studies, this research(%)	All Research%
pre-1990	36 (31.30)	18.7374
1990's	73 (63.48)	18.2507
2000's	4 (3.48)	29.6817
2010's	1 (0.87)	24.3611
2020's	1 (0.87)	2.80

Authors

Authors	Studies
Cegła, MT; Duszyńska, B; Mokrosz, JL; Pietrasiewicz, M	1
Glennon, RA	1
Chilmonczyk, Z; Cybulski, J; Gdaniec, M; Kozioł, AE; Leś, A; Woźniakowska, A	1
Adam, G; Caignard, DH; Guardiola-Lemaître, B; Guillaumet, G; Pfeiffer, B; Podona, T; Renard, P	1
Soudijn, W; Tulp, MT; van Steen, BJ; van Wijngaarden, I	1
Adam, G; Baudin, ML; Caignard, DH; Comoy, C; Guardiola-Lemaitre, B; Guillaumet, G; Marot, C; Morin-Allory, L; Pfeiffer, B; Podona, T; Renard, P; Rettori, MC	1
Chaput, C; Millan, MJ; Newman-Tancredi, A; Verrièle, L	1
Audinot, V; Chaput, C; Conte, C; Gavaudan, S; Millan, MJ; Newman-Tancredi, A; Touzard, M; Verrièle, L	1
Buck, LB; Petrascheck, M; Ye, X	1
Jaśkowska, J; Kułaga, D; Satała, G	1
Berthold, EC; Canal, CE; Chen, Y; Gamez-Jimenez, LR; Hampson, AJ; Hiranita, T; Kamble, SH; King, TI; León, F; Lopera-Londoño, C; McCurdy, CR; McMahon, LR; Mottinelli, M; Obeng, S; Patel, A; Restrepo, LF; Sharma, A	1
Akiyama, K; Chen, CC; Fujiwara, Y; Moriya, F; Otsuki, S; Ujike, H	1
Fanelli, RJ; McMonagle-Strucko, K	1
Alvarez Sanz, MC; Levy, AD; Li, Q; Rittenhouse, PA; Van de Kar, LD	1
Murthy, JN; Pranzatelli, MR	1
Heal, DJ; Hearson, M; Martin, KF; Phillips, I; Prow, MR	1
Rigdon, GC; Weatherspoon, JK	1
Kelder, D; Ross, SB	1
Baudrie, V; Bluet-Pajot, MT; Broqua, P; Chaouloff, F	1
Bolaños, FJ; Fattaccini, CM; Gozlan, H; Haj-Dahmane, S; Hamon, M; Lanfumey, L; Laporte, AM; Schechter, LE	1
Baudrie, V; Chaouloff, F	1
Cornelissen, JC; de Kloet, ER; Schipper, J; Sijbesma, H	1
Hjorth, S	1
Antón-Tay, F; Benítez-King, G; Chávez, JL; Hong, E; Martínez, I	1
Brown, CM; Redfern, WS; Small, C; Spedding, M	1
Edwards, E; Nemeroff, CB; Owens, MJ	1
Bohmaker, K; Goldstein, M; Meller, E	1
Darrow, EJ; Strahlendorf, HK; Strahlendorf, JC	1
Francès, H; Khidichian, F; Monier, C	1
Kalkman, HO	2
Eison, AS; Margraf, RR; Wright, RN; Yocca, FD	1
Edwards, E; Harkins, K; Whitaker-Azmitia, PM	1
Davies, M; Fletcher, PJ	1
Davidoff, RA; Hackman, JC; Holohean, AM	1
Frambes, NA; Kirstein, CL; Moody, CA; Spear, LP	1
Bielenberg, GW; Burkhardt, M	1
Bode-Greuel, KM; Glaser, T; Horváth, E; Klisch, J; Traber, J	1
Fredow, G; Glaser, T; Löscher, W; Traber, J; Witte, U	1
Kalkman, HO; Soar, J	1
Bluet-Pajot, MT; Di Sciullo, A; Kordon, C; Mounier, F; Oliver, C; Schmidt, B	1
Davidoff, RA; Gharagozloo, A; Hackman, JC; Holohean, AM	1
Marsden, CA; Martin, KF	1
Bradbury, AJ; Higgins, GA; Jones, BJ; Oakley, NR	1
Adrien, J; Fattaccini, CM; Gozlan, H; Hamon, M; Lanfumey, L	1
Azmitia, EC; Segal, M; Whitaker-Azmitia, PM	1
Berendsen, HH; Broekkamp, CL; Jenck, F	1
Meltzer, HY; Nash, JF	1
Engel, JA; Hjorth, S; Söderpalm, B	1
Rauch, RJ; Stephenson, JD; Stolerman, IP	1
Cooper, SJ; Desa, A	1
Peroutka, SJ	1
Aghajanian, GK; Sprouse, JS	2
Gorzalka, BB; Mendelson, SD	1
Spencer, DG; Traber, J	1
Fozard, JR; Kidd, EJ; Neill, J; Tricklebank, MD	1
Curzon, G; Dourish, CT; Kennett, GA	1
Gonzales, DA; Peroutka, SJ; Shapiro, M	1
Giral, P; Martin, P; Simon, P; Soubrié, P	1
Dourish, CT; Gilbert, F	1
Cassella, JV; Davis, M; Kehne, JH	1
Pranzatelli, MR	1
Winter, JC	1
Brazell, C; Gilbert, F; Stahl, SM; Tricklebank, MD	1
Hiner, BC; Kocsis, JD; Mauk, MD; Peroutka, SJ	1
Fallon, SL; Sinton, CM	1
Brazell, C; Dourish, CT; Gilbert, F; McClue, S; Stahl, SM	1
De Souza, RJ; Goodwin, GM; Green, AR	1
Göthert, M; Kollecker, P; Rohm, N; Zerkowski, HR	1
Peroutka, SJ; Smith, LM	1
De Souza, RJ; Goodwin, GM; Green, AR; Heal, DJ	1
Lorens, SA; Van de Kar, LD	1
Gallagher, JP; Joëls, M; Shinnick-Gallagher, P	1
Fozard, JR; Ramage, AG	1
Geyer, MA; Mansbach, RS	1
Fernández-Guasti, A; López-Rubalcava, C; Picazo, O	1
Fernández-Guasti, A; López-Rubalcava, C	2
Baudrie, V; Bluet-Pajot, MT; Broqua, P; Chaouloff, F; Laude, D; Schmidt, B	1
Emerit, MB; Hamon, M; Riad, M	1
Adrien, J; Chastanet, M; De Vry, J; Glaser, T; Hamon, M; Jolas, T; Laporte, AM; Schreiber, R	1
Cole, BJ; Jones, GH; Turner, JD	1
Hepner, BC; Pomerantz, SM; Wertz, JM	1
De Vry, J; Glaser, T; Opitz, K; Schreiber, R	1
Evenden, JL; Petterson, M; Ryan, CN	1
Bramwell, S; Hjorth, S; McQuade, R; Sharp, T	1
De Vry, J; Schreiber, R	2
Bell, R; Hobson, H	1
Olivier, B; Slangen, JL; Ybema, CE	1
Lum-Ragan, JT; Piercey, MF; Smith, MW	1
Cox, RF; Meller, E; Waszczak, BL	1
Ciccocioppo, R; Cooper, SJ	1
Bagdy, G; Kalogeras, KT	1
Bohmaker, K; Eison, AS; Meller, E; Yocca, FD	1
Korneyev, AY; Seredenin, SB	1
Dunn, AJ; Farrar, GE; Saphier, D; Welch, JE	1
Sánchez, C	1
Löscher, W; Richter, A	1
Morgan, D; Picker, MJ	1
Dykstra, LA; Powell, KR	1
Matheson, GK; Raess, BU; Tunnicliff, G	1
Fornal, CA; Jacobs, BL; Marrosu, F; Metzler, CW	1
Herremans, AH; Mos, J; Olivier, B; Van Drimmelen, M; Van Hest, A	1
Bagdy, G	1
Korf, J; Korte, SM; Luiten, PG; Nyakas, C; Oosterink, BJ	1
Ronken, E; Soudijn, W; van Steen, BJ; van Wijngaarden, I	1
de Boer, SF; Koolhaas, JM; Lesourd, M; Mocaer, E	1
Amstislavskaia, TG; Ivanova, EA; Kucheriavyĭ, SA; Popova, NK	1
Cruz, SL; Fernández-Guasti, A; López-Rubalcava, C	1
Cryan, JF; Kelliher, P; Kelly, JP; Leonard, BE	1
Davidson, C; Hopwood, SE; McLaughlin, DP; Stamford, JA	1
Alberti, I; Boni, C; De Felipe, C; Froger, N; Gardier, AM; Hamon, M; Hunt, SP; Jacquot, C; Lanfumey, L; Lena, I; Moratalla, R; Rupniak, NM	1
Eckler, JR; Rabin, RA; Reissig, CJ; Winter, JC	1

Reviews

4 review(s) available for 8-hydroxy-2-(di-n-propylamino)tetralin and ipsapirone

Article	Year
Central serotonin receptors as targets for drug research. Journal of medicinal chemistry, 1987, Volume: 30, Issue:1 Topics: Animals; Humans; Receptors, Serotonin; Research Design; Serotonin	1987
Classification of opioid and 5-hydroxytryptamine receptors by means of discriminative drug effects. Neuropharmacology, 1987, Volume: 26, Issue:7B Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Conditioning, Classical; Cyclazocine; Discrimination Learning; Dose-Response Relationship, Drug; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Ethylketocyclazocine; Lysergic Acid Diethylamide; Narcotics; Nicotine; Piperazines; Pyrimidines; Receptors, Opioid; Receptors, Serotonin; Research Design; Tetrahydronaphthalenes	1987
5-HT1A receptor influences on rodent social and agonistic behavior: a review and empirical study. Neuroscience and biobehavioral reviews, 1994,Fall, Volume: 18, Issue:3 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Agonistic Behavior; Animals; Dioxins; Male; Mice; Pyrimidines; Receptors, Serotonin; Serotonin Receptor Agonists; Social Behavior; Spiro Compounds	1994
Control of dorsal raphé 5-HT function by multiple 5-HT(1) autoreceptors: parallel purposes or pointless plurality? Trends in neurosciences, 2000, Volume: 23, Issue:10 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antidepressive Agents, Second-Generation; Autoreceptors; Dimerization; Guinea Pigs; Humans; Ion Channels; Ion Transport; Mice; Nerve Tissue Proteins; Neurons; Oxadiazoles; Piperazines; Protein Isoforms; Pyridines; Pyrimidines; Raphe Nuclei; Rats; Receptor, Serotonin, 5-HT1B; Receptor, Serotonin, 5-HT1D; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Second Messenger Systems; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Receptor Agonists; Spiperone; Sumatriptan	2000

Other Studies

111 other study(ies) available for 8-hydroxy-2-(di-n-propylamino)tetralin and ipsapirone

Article	Year
Structure-activity relationship studies of central nervous system agents. 5. Effect of the hydrocarbon chain on the affinity of 4-substituted 1-(3-chlorophenyl)piperazines for 5-HT1A receptor site. Journal of medicinal chemistry, 1992, Jun-26, Volume: 35, Issue:13 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Brain; Central Nervous System; Hydrocarbons; Piperazines; Radioligand Assay; Rats; Receptors, Serotonin; Structure-Activity Relationship; Substrate Specificity; Tetrahydronaphthalenes	1992
Buspirone analogues as ligands of the 5-HT1A receptor. 1. The molecular structure of buspirone and its two analogues. Journal of medicinal chemistry, 1995, May-12, Volume: 38, Issue:10 Topics: Buspirone; Carbon Isotopes; Cations; Electrochemistry; Ligands; Magnetic Resonance Spectroscopy; Molecular Structure; Piperazines; Protons; Receptors, Serotonin	1995
3,4-Dihydro-3-amino-2H-1-benzopyran derivatives as 5-HT1A receptor ligands and potential anxiolytic agents. 1. Synthesis and structure--activity relationship studies. Journal of medicinal chemistry, 1994, Jun-10, Volume: 37, Issue:12 Topics: Animals; Anti-Anxiety Agents; Benzopyrans; Binding Sites; Brain; Columbidae; In Vitro Techniques; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Stereoisomerism; Structure-Activity Relationship	1994
Structure-affinity relationship studies on 5-HT1A receptor ligands. 1. Heterobicyclic phenylpiperazines with N4-alkyl substituents. Journal of medicinal chemistry, 1993, Sep-17, Volume: 36, Issue:19 Topics: Animals; Binding Sites; Brain; Bridged Bicyclo Compounds; Piperazines; Rats; Receptors, Serotonin; Structure-Activity Relationship	1993
3-amino-3,4-dihydro-2H-1-benzopyran derivatives as 5-HT1A receptor ligands and potential anxiolytic agents. 2. Synthesis and quantitative structure-activity relationship studies of spiro[pyrrolidine- and piperidine-2,3'(2'H)-benzopyrans]. Journal of medicinal chemistry, 1996, Oct-11, Volume: 39, Issue:21 Topics: Animals; Anti-Anxiety Agents; Benzopyrans; Colforsin; Cyclic AMP; Hippocampus; Maze Learning; Mice; Models, Molecular; Rats; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Spiro Compounds; Structure-Activity Relationship	1996
Labelling of recombinant human and native rat serotonin 5-HT1A receptors by a novel, selective radioligand, [3H]-S 15535: definition of its binding profile using agonists, antagonists and inverse agonists. Naunyn-Schmiedeberg's archives of pharmacology, 1998, Volume: 357, Issue:3 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Affinity Labels; Animals; Binding, Competitive; CHO Cells; Cricetinae; Guanine Nucleotides; Hippocampus; Humans; Male; Membranes; Piperazines; Radiopharmaceuticals; Rats; Rats, Wistar; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Receptor Agonists	1998
Agonist and antagonist actions of antipsychotic agents at 5-HT1A receptors: a [35S]GTPgammaS binding study. European journal of pharmacology, 1998, Aug-21, Volume: 355, Issue:2-3 Topics: Animals; Antipsychotic Agents; CHO Cells; Cricetinae; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Agents; Sulfur Radioisotopes	1998
An antidepressant that extends lifespan in adult Caenorhabditis elegans. Nature, 2007, Nov-22, Volume: 450, Issue:7169 Topics: Aging; Animals; Antidepressive Agents; Caenorhabditis elegans; Caloric Restriction; Humans; Longevity; Methiothepin; Mianserin; Octopamine; Receptors, Biogenic Amine; Receptors, Serotonin, 5-HT4; Serotonin; Serotonin 5-HT4 Receptor Antagonists; Serotonin Antagonists; Signal Transduction; Starvation	2007
Design, synthesis and biological evaluation of novel serotonin and dopamine receptor ligands being 6-bromohexyl saccharine derivatives. Bioorganic & medicinal chemistry letters, 2019, 11-01, Volume: 29, Issue:21 Topics: Antidepressive Agents; Binding Sites; Dopamine Antagonists; Drug Evaluation, Preclinical; Ligands; Models, Molecular; Molecular Structure; Piperazines; Protein Binding; Receptors, Dopamine; Receptors, Serotonin; Saccharin; Serotonin; Serotonin Antagonists; Structure-Activity Relationship; Thermodynamics	2019
Activity of Journal of medicinal chemistry, 2021, 09-23, Volume: 64, Issue:18 Topics: Analgesics; Animals; Behavior, Animal; Female; HEK293 Cells; Humans; Male; Nociceptive Pain; Rats, Sprague-Dawley; Receptors, Serotonin; Secologanin Tryptamine Alkaloids	2021
Voluntary intake of alcohol is attenuated by ipsapirone in mice and role of 5-HT1A receptor. The Japanese journal of psychiatry and neurology, 1992, Volume: 46, Issue:1 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Alcohol Drinking; Animals; Anti-Anxiety Agents; Hippocampus; Male; Mice; Mice, Inbred C57BL; Pyrimidines; Radioligand Assay; Receptors, Serotonin; Serotonin; Synaptic Membranes; Tetrahydronaphthalenes	1992
Alteration of 5-HT1A receptor binding sites following chronic treatment with ipsapirone measured by quantitative autoradiography. Synapse (New York, N.Y.), 1992, Volume: 12, Issue:1 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antipsychotic Agents; Autoradiography; Body Weight; Kinetics; Male; Pyrimidines; Rats; Receptors, Serotonin; Time Factors; Tritium	1992
Neuroendocrine responses to the serotonin2 agonist DOI are differentially modified by three 5-HT1A agonists. Neuropharmacology, 1992, Volume: 31, Issue:10 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenocorticotropic Hormone; Amphetamines; Animals; Anti-Anxiety Agents; Buspirone; Corticosterone; Male; Neurosecretory Systems; Prolactin; Pyrimidines; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Renin; Serotonin Receptor Agonists	1992
Brainstem 5-hydroxytrytamine1A binding sites are not down-regulated by agonists which induce tolerance in the rat: myoclonus and other serotonergic behaviors. Journal of receptor research, 1992, Volume: 12, Issue:3 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Behavior, Animal; Brain Stem; Buspirone; Down-Regulation; Drug Tolerance; Male; Myoclonus; Pyrimidines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin; Tetrahydronaphthalenes	1992
Characterization of 8-OH-DPAT-induced hypothermia in mice as a 5-HT1A autoreceptor response and its evaluation as a model to selectively identify antidepressants. British journal of pharmacology, 1992, Volume: 107, Issue:1 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antidepressive Agents; Body Temperature; Buspirone; Dose-Response Relationship, Drug; Down-Regulation; Hypothermia; Male; Mice; Mice, Inbred C57BL; Parasympatholytics; Pyrimidines; Receptors, Dopamine D2; Receptors, Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists	1992
5-Hydroxytryptamine 1a receptor agonists block prepulse inhibition of acoustic startle reflex. The Journal of pharmacology and experimental therapeutics, 1992, Volume: 263, Issue:2 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Acoustic Stimulation; Animals; Buspirone; Dose-Response Relationship, Drug; Drug Interactions; Haloperidol; Male; Methoxydimethyltryptamines; Pyrimidines; Rats; Rats, Wistar; Receptors, Serotonin; Reflex, Startle; Schizophrenia; Serotonin Receptor Agonists	1992
Long lasting attenuation of 8-OH-DPAT-induced corticosterone secretion after a single injection of a 5-HT1A receptor agonist. Naunyn-Schmiedeberg's archives of pharmacology, 1992, Volume: 346, Issue:2 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Buspirone; Corticosterone; Drug Interactions; Hydrocortisone; Injections; Male; Piperazines; Pyrimidines; Rats; Rats, Sprague-Dawley; Sensitivity and Specificity; Serotonin Receptor Agonists; Time Factors	1992
Buspirone, ipsapirone and 1-(2-pyrimidinyl)-piperazine decrease cold-induced thyrotropin secretion in rats. European journal of pharmacology, 1991, Nov-05, Volume: 204, Issue:2 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic alpha-Antagonists; Animals; Anti-Anxiety Agents; Buspirone; Cold Temperature; Hypothalamo-Hypophyseal System; Male; Pyrimidines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Tetrahydronaphthalenes; Thyroid Gland; Thyrotropin	1991
Alterations of central serotoninergic and dopaminergic neurotransmission in rats chronically treated with ipsapirone: biochemical and electrophysiological studies. The Journal of pharmacology and experimental therapeutics, 1990, Volume: 255, Issue:3 Topics: 3,4-Dihydroxyphenylacetic Acid; 5-Hydroxytryptophan; 8-Hydroxy-2-(di-n-propylamino)tetralin; Adenylyl Cyclases; Animals; Autoradiography; Behavior, Animal; Binding Sites; Biogenic Amines; Body Weight; Brain; Brain Stem; Dihydroxyphenylalanine; Dopamine; Drug Administration Schedule; Electrophysiology; Hippocampus; Homovanillic Acid; Hydroxyindoleacetic Acid; Male; Membranes; Neurons; Pyrimidines; Raphe Nuclei; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Synaptic Transmission; Tetrahydronaphthalenes; Time Factors	1990
Repeated treatment with the 5-HT1A receptor agonist, ipsapirone, does not affect 8-OH-DPAT- and stress-induced increases in plasma adrenaline levels in the rat. European journal of pharmacology, 1991, Jun-06, Volume: 198, Issue:2-3 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Blood Glucose; Body Weight; Chromatography, High Pressure Liquid; Corticosterone; Epinephrine; Immobilization; Male; Pyrimidines; Radioimmunoassay; Rats; Rats, Inbred Strains; Receptors, Serotonin; Stress, Physiological; Tetrahydronaphthalenes	1991
Species differences in the distribution of central 5-HT1 binding sites: a comparative autoradiographic study between rat and guinea pig. Brain research, 1991, Aug-02, Volume: 555, Issue:2 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Autoradiography; Brain; Guinea Pigs; Ligands; Male; Piperazines; Pyrimidines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin Antagonists; Species Specificity; Tetrahydronaphthalenes	1991
Single-dose 8-OH-DPAT pretreatment does not induce tachyphylaxis to the 5-HT release-reducing effect of 5-HT1A autoreceptor agonists. European journal of pharmacology, 1991, Jun-25, Volume: 199, Issue:2 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Binding Sites; Feedback; Hippocampus; Male; Piperazines; Pyrimidines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin; Tachyphylaxis; Tetrahydronaphthalenes	1991
Further evidence that indorenate is a 5-HT1 agonist. Proceedings of the Western Pharmacology Society, 1991, Volume: 34 Topics: 5-Methoxytryptamine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antihypertensive Agents; Binding, Competitive; Guanosine Triphosphate; Hippocampus; In Vitro Techniques; Male; Membranes; Potassium; Pyrimidines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Tetrahydronaphthalenes	1991
The guinea-pig ileum preparation as a model for 5-HT1A receptors: anomalous effects with RS-30199-193. British journal of pharmacology, 1991, Volume: 104, Issue:2 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Azepines; Buspirone; Calcium; Drug Interactions; Female; Guinea Pigs; Ileum; In Vitro Techniques; Models, Biological; Muscle, Smooth; Naphthalenes; Phorbol 12,13-Dibutyrate; Pyrimidines; Radioligand Assay; Receptors, Serotonin; Reproducibility of Results; Spiro Compounds; Tetrahydronaphthalenes; Tryptamines	1991
Effects of 5-HT1A receptor agonists on hypothalamo-pituitary-adrenal axis activity and corticotropin-releasing factor containing neurons in the rat brain. European journal of pharmacology, 1990, Nov-06, Volume: 190, Issue:1-2 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenocorticotropic Hormone; Animals; Binding, Competitive; Brain; Brain Chemistry; Corticosterone; Corticotropin-Releasing Hormone; Hypothalamo-Hypophyseal System; Kinetics; Male; Neurons; Pituitary-Adrenal System; Pyrimidines; Radioimmunoassay; Rats; Rats, Inbred Strains; Receptors, Glucocorticoid; Receptors, Serotonin; Serotonin Antagonists; Tetrahydronaphthalenes	1990
Receptor reserve for 5-hydroxytryptamine1A-mediated inhibition of serotonin synthesis: possible relationship to anxiolytic properties of 5-hydroxytryptamine1A agonists. Molecular pharmacology, 1990, Volume: 37, Issue:2 Topics: 5-Hydroxytryptophan; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Anti-Anxiety Agents; Buspirone; Cerebral Cortex; Hippocampus; Male; Piperazines; Pyrimidines; Quinolines; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Serotonin; Serotonin; Tetrahydronaphthalenes	1990
Response of cerebellar Purkinje cells to serotonin and the 5-HT1A agonists 8-OH-DPAT and ipsapirone in vitro. European journal of pharmacology, 1990, Jan-10, Volume: 175, Issue:2 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Anti-Anxiety Agents; Cerebellum; Iontophoresis; Male; Naphthalenes; Purkinje Cells; Pyrimidines; Rats; Rats, Inbred Strains; Serotonin; Spiperone; Tetrahydronaphthalenes	1990
Increase in the isolation-induced social behavioural deficit by agonists at 5-HT1A receptors. Neuropharmacology, 1990, Volume: 29, Issue:2 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Anti-Anxiety Agents; Buspirone; Exploratory Behavior; Male; Mice; Motor Activity; Penbutolol; Piperazines; Pyrimidines; Receptors, Serotonin; Social Behavior; Social Isolation; Tetrahydronaphthalenes	1990
Discriminative stimulus properties of 8-OH-DPAT in rats are not altered by pretreatment with para-chlorophenylalanine. Psychopharmacology, 1990, Volume: 101, Issue:1 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Brain Chemistry; Discrimination, Psychological; Dose-Response Relationship, Drug; Fenclonine; Generalization, Psychological; Male; Naphthalenes; Neurotransmitter Agents; Pyrimidines; Rats; Rats, Inbred Strains; Tetrahydronaphthalenes	1990
8-OH-DPAT and buspirone analogs inhibit the ketanserin-sensitive quipazine-induced head shake response in rats. Pharmacology, biochemistry, and behavior, 1990, Volume: 35, Issue:1 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Buspirone; Head; Ketanserin; Male; Naphthalenes; Pindolol; Pyrimidines; Quinolines; Quipazine; Rats; Rats, Inbred Strains; Receptors, Serotonin; Stereotyped Behavior; Tetrahydronaphthalenes	1990
5-HT1A and 5-HT1B agonists play a differential role on the respiratory frequency in rats. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 1990, Volume: 3, Issue:2 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Dose-Response Relationship, Drug; Male; Naphthalenes; Piperazines; Pyrimidines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Reference Values; Respiration; Tetrahydronaphthalenes	1990
The involvement of 5-hydroxytryptaminergic and dopaminergic mechanisms in the eating induced by buspirone, gepirone and ipsapirone. British journal of pharmacology, 1990, Volume: 99, Issue:3 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Buspirone; Dopamine; Dose-Response Relationship, Drug; Eating; Fenclonine; Haloperidol; Male; Pyrimidines; Raphe Nuclei; Rats; Rats, Inbred Strains; Serotonin; Tetrahydronaphthalenes	1990
Changes in membrane potential of frog motoneurons induced by activation of serotonin receptor subtypes. Neuroscience, 1990, Volume: 34, Issue:3 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Membrane Potentials; Motor Neurons; Pyrimidines; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Spinal Cord; Spiperone; Tetrahydronaphthalenes	1990
5-HT1A, 5-HT1B and 5-HT2 receptor agonists induce differential behavioral responses in preweanling rat pups. European journal of pharmacology, 1990, Jun-21, Volume: 182, Issue:1 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Animals, Newborn; Behavior, Animal; Eating; Female; Grooming; Hindlimb; Male; Milk; Motor Activity; Piperazines; Pyrimidines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Tetrahydronaphthalenes	1990
5-hydroxytryptamine1A agonists. A new therapeutic principle for stroke treatment. Stroke, 1990, Volume: 21, Issue:12 Suppl Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Brain; Buspirone; Indoles; Ischemic Attack, Transient; Mice; Pyrimidines; Rats; Rats, Inbred F344; Receptors, Serotonin; Tetrahydronaphthalenes	1990
Effects of 5-hydroxytryptamine1A-receptor agonists on hippocampal damage after transient forebrain ischemia in the Mongolian gerbil. Stroke, 1990, Volume: 21, Issue:12 Suppl Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Cell Survival; Gerbillinae; Hippocampus; Indoles; Ischemic Attack, Transient; Neurons; Pyrimidines; Receptors, Serotonin; Tetrahydronaphthalenes	1990
The behavioural responses to 8-OH-DPAT, ipsapirone and the novel 5-HT1A receptor agonist Bay Vq 7813 in the pig. Naunyn-Schmiedeberg's archives of pharmacology, 1990, Volume: 342, Issue:3 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adenylyl Cyclases; Animals; Behavior, Animal; Female; Hippocampus; Male; Membranes; Piperazines; Pyrimidines; Receptors, Serotonin; Swine; Tetrahydronaphthalenes	1990
Determination of the 5-HT receptor subtype involved in 8-OH-DPAT-induced hyperlocomotion: potential difficulties arising from inadequate pharmacological tools. European journal of pharmacology, 1990, Dec-04, Volume: 191, Issue:3 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Buspirone; Dioxanes; Haloperidol; Male; Motor Activity; Pindolol; Pyrimidines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin Antagonists; Spiro Compounds; Tetrahydronaphthalenes	1990
Changes in anterior pituitary hormone levels after serotonin 1A receptor stimulation. Endocrinology, 1990, Volume: 127, Issue:2 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenocorticotropic Hormone; Animals; Growth Hormone; Luteinizing Hormone; Male; Piperazines; Pituitary Gland, Anterior; Pituitary Hormones, Anterior; Prolactin; Pyrimidines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Reference Values; Serotonin; Serotonin Antagonists; Tetrahydronaphthalenes; Thyrotropin	1990
Serotonin and GABA-induced depolarizations of frog primary afferent fibers. Brain research, 1990, Nov-05, Volume: 532, Issue:1-2 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Afferent Pathways; Animals; gamma-Aminobutyric Acid; In Vitro Techniques; Membrane Potentials; Pyrimidines; Rana pipiens; Receptors, GABA-A; Serotonin; Serotonin Antagonists; Spinal Cord; Tetrahydronaphthalenes; Tetrodotoxin	1990
Involvement of 5-HT1A- and alpha 2-receptors in the decreased 5-hydroxytryptamine release and metabolism in rat suprachiasmatic nucleus after intravenous 8-hydroxy-2-(n-dipropylamino) tetralin. British journal of pharmacology, 1986, Volume: 89, Issue:2 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Anti-Anxiety Agents; Dioxanes; Hydroxyindoleacetic Acid; Idazoxan; Male; Methiothepin; Naphthalenes; Pyrimidines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Serotonin; Serotonin; Suprachiasmatic Nucleus; Tetrahydronaphthalenes	1986
Behavioural and biochemical consequences following activation of 5HT1-like and GABA receptors in the dorsal raphé nucleus of the rat. Neuropharmacology, 1988, Volume: 27, Issue:10 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Anti-Anxiety Agents; Avoidance Learning; Body Temperature; Brain; Buspirone; Hydroxyindoleacetic Acid; Male; Muscimol; Posture; Pyrimidines; Raphe Nuclei; Rats; Rats, Inbred Strains; Receptors, GABA-A; Receptors, Serotonin; Social Behavior; Tetrahydronaphthalenes; Tissue Distribution	1988
Biochemical and electrophysiological evidence for an agonist action of CM 57493 at pre- and postsynaptic 5-hydroxytryptamine1A receptors in brain. The Journal of pharmacology and experimental therapeutics, 1989, Volume: 248, Issue:3 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adenylyl Cyclases; Animals; Brain; Brain Chemistry; Dopamine; In Vitro Techniques; Male; Pyridines; Pyrimidines; Raphe Nuclei; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin; Tetrahydronaphthalenes	1989
Physiological effects of selective 5-HT1a and 5-HT1b ligands in rat hippocampus: comparison to 5-HT. Brain research, 1989, Nov-13, Volume: 502, Issue:1 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Action Potentials; Animals; Hippocampus; In Vitro Techniques; Male; Neural Inhibition; Piperazines; Pyrimidines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin; Tetrahydronaphthalenes	1989
Selective activation of 5HT1A receptors induces lower lip retraction in the rat. Pharmacology, biochemistry, and behavior, 1989, Volume: 33, Issue:4 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Behavior, Animal; Buspirone; Dose-Response Relationship, Drug; Indoles; Lip; Male; Muscles; Naphthalenes; Pyrimidines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin Antagonists; Tetrahydronaphthalenes	1989
Effect of gepirone and ipsapirone on the stimulated and unstimulated secretion of prolactin in the rat. The Journal of pharmacology and experimental therapeutics, 1989, Volume: 249, Issue:1 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; alpha-Methyltyrosine; Animals; Anti-Anxiety Agents; Electric Stimulation; Haloperidol; Male; Methoxydimethyltryptamines; Methyltyrosines; Prolactin; Pyrazines; Pyrimidines; Rats; Rats, Inbred Strains; Receptors, Dopamine; Tetrahydronaphthalenes	1989
Effects of 5-HT1A receptor agonists and L-5-HTP in Montgomery's conflict test. Pharmacology, biochemistry, and behavior, 1989, Volume: 32, Issue:1 Topics: 5-Hydroxytryptophan; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Anti-Anxiety Agents; Buspirone; Conflict, Psychological; Male; Motor Activity; Pyrimidines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Tetrahydronaphthalenes	1989
Beta-adrenoceptor blockade in rats enhances the ambulation induced by 5-HT1A receptor agonists. European journal of pharmacology, 1989, Dec-07, Volume: 173, Issue:2-3 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic beta-Antagonists; Animals; Male; Motor Activity; Pindolol; Piperazines; Pyrimidines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Tetrahydronaphthalenes	1989
Benzodiazepines and putative 5-HT1A agonists increase hypertonic saline consumption in rehydrating rats. Pharmacology, biochemistry, and behavior, 1987, Volume: 28, Issue:2 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Anti-Anxiety Agents; Benzodiazepines; Drinking; Male; Midazolam; Naphthalenes; Pyrimidines; Rats; Rats, Inbred Strains; Receptors, GABA-A; Receptors, Serotonin; Saline Solution, Hypertonic; Self Administration; Sodium Chloride; Tetrahydronaphthalenes	1987
Selective interaction of novel anxiolytics with 5-hydroxytryptamine1A receptors. Biological psychiatry, 1985, Volume: 20, Issue:9 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Anti-Anxiety Agents; Binding, Competitive; Brain; Buspirone; Cattle; Depression, Chemical; Diazepam; Flunitrazepam; In Vitro Techniques; Lorazepam; Pyrimidines; Receptors, Serotonin; Tetrahydronaphthalenes	1985
(-)-Propranolol blocks the inhibition of serotonergic dorsal raphe cell firing by 5-HT1A selective agonists. European journal of pharmacology, 1986, Sep-09, Volume: 128, Issue:3 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Anti-Anxiety Agents; In Vitro Techniques; Iontophoresis; Male; Propranolol; Pyrimidines; Raphe Nuclei; Rats; Rats, Inbred Strains; Receptors, Serotonin; Stereoisomerism; Tetrahydronaphthalenes	1986
Effects of 5-HT1A selective anxiolytics on lordosis behavior: interactions with progesterone. European journal of pharmacology, 1986, Dec-16, Volume: 132, Issue:2-3 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Anti-Anxiety Agents; Buspirone; Drug Interactions; Estrogens; Posture; Progesterone; Pyrimidines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Sexual Behavior, Animal; Tetrahydronaphthalenes	1986
The interoceptive discriminative stimuli induced by the novel putative anxiolytic TVX Q 7821: behavioral evidence for the specific involvement of serotonin 5-HT1A receptors. Psychopharmacology, 1987, Volume: 91, Issue:1 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Anti-Anxiety Agents; Brain; Buspirone; Male; Methoxydimethyltryptamines; Pyrimidines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Tetrahydronaphthalenes	1987
Mediation of the discriminative stimulus properties of 8-hydroxy-2-(di-n-propylamino) tetralin (8-OH-DPAT) by the putative 5-HT1A receptor. European journal of pharmacology, 1987, Jan-06, Volume: 133, Issue:1 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Alprenolol; Animals; Buspirone; Discrimination Learning; Dose-Response Relationship, Drug; Generalization, Psychological; Male; Naphthalenes; Pindolol; Pyrimidines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Tetrahydronaphthalenes	1987
Antidepressant-like action of 5-HT1A agonists and conventional antidepressants in an animal model of depression. European journal of pharmacology, 1987, Feb-24, Volume: 134, Issue:3 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Anti-Anxiety Agents; Antidepressive Agents; Benzodiazepines; Buspirone; Depressive Disorder; Disease Models, Animal; Drug Interactions; Indoles; Male; Motor Activity; Pyrimidines; Rats; Rats, Inbred Strains; Restraint, Physical; Serotonin; Stress, Psychological; Tetrahydronaphthalenes	1987
Modulation of postdecapitation convulsions in rats by alpha-adrenergic and 5-hydroxytryptamine1A agents. Experimental neurology, 1987, Volume: 96, Issue:2 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic alpha-Agonists; Animals; Buspirone; Death; Dioxanes; Male; Prazosin; Pyrimidines; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Serotonin; Seizures; Serotonin; Tetrahydronaphthalenes; Yohimbine	1987
Reversal of helpless behavior in rats by putative 5-HT1A agonists. Biological psychiatry, 1988, Feb-01, Volume: 23, Issue:3 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Anti-Anxiety Agents; Avoidance Learning; Buspirone; Escape Reaction; Helplessness, Learned; Male; Naphthalenes; Pyrimidines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Tetrahydronaphthalenes	1988
Effects of the novel anxiolytics gepirone, buspirone and ipsapirone on free feeding and on feeding induced by 8-OH-DPAT. Psychopharmacology, 1987, Volume: 93, Issue:3 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Anti-Anxiety Agents; Buspirone; Eating; Hyperphagia; Male; Naphthalenes; Pyrimidines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Tetrahydronaphthalenes	1987
Serotonin does not mediate anxiolytic effects of buspirone in the fear-potentiated startle paradigm: comparison with 8-OH-DPAT and ipsapirone. Psychopharmacology, 1988, Volume: 94, Issue:1 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Acoustic Stimulation; Animals; Anti-Anxiety Agents; Buspirone; Conditioning, Operant; Fear; Fenclonine; Male; Pyrimidines; Raphe Nuclei; Rats; Rats, Inbred Strains; Reflex, Startle; Serotonin; Serotonin Antagonists; Tetrahydronaphthalenes	1988
The comparative pharmacology of the behavioral syndromes induced by TRH and by 5-HT in the rat. General pharmacology, 1988, Volume: 19, Issue:2 Topics: 5-Hydroxytryptophan; 5,7-Dihydroxytryptamine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Anti-Anxiety Agents; Antidepressive Agents; Behavior, Animal; Body Temperature; Cisterna Magna; Injections; Male; Pyrimidines; Rats; Rats, Inbred Strains; Serotonin; Tetrahydronaphthalenes; Thiazolidines; Thyrotropin-Releasing Hormone	1988
Generalization of the discriminative stimulus properties of 8-hydroxy-2-(di-n-propylamino)tetralin (8-OH-DPAT) and ipsapirone to yohimbine. Pharmacology, biochemistry, and behavior, 1988, Volume: 29, Issue:1 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Anti-Anxiety Agents; Generalization, Stimulus; Male; Naphthalenes; Pyrimidines; Rats; Rats, Inbred F344; Tetrahydronaphthalenes; Yohimbine	1988
Activation of the 5-HT1A receptor subtype increases rat plasma ACTH concentration. European journal of pharmacology, 1988, Mar-15, Volume: 147, Issue:3 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenocorticotropic Hormone; Animals; Anti-Anxiety Agents; Buspirone; Male; Physostigmine; Pindolol; Pyrimidines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Tetrahydronaphthalenes	1988
Responses of hippocampal pyramidal cells to putative serotonin 5-HT1A and 5-HT1B agonists: a comparative study with dorsal raphe neurons. Neuropharmacology, 1988, Volume: 27, Issue:7 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Action Potentials; Animals; Anti-Anxiety Agents; Hippocampus; Male; Piperazines; Pyrimidines; Raphe Nuclei; Rats; Rats, Inbred Strains; Receptors, Serotonin; Tetrahydronaphthalenes	1988
Buspirone, 8-OH-DPAT and ipsapirone: effects on hippocampal cerebellar and sciatic fiber excitability. Brain research, 1988, Sep-27, Volume: 461, Issue:1 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Anti-Anxiety Agents; Buspirone; Cerebellum; Evoked Potentials; Hippocampus; In Vitro Techniques; Male; Naphthalenes; Nerve Fibers; Organ Specificity; Pyrimidines; Rats; Rats, Inbred Strains; Sciatic Nerve; Serotonin; Tetrahydronaphthalenes	1988
Electrophysiological evidence for a functional differentiation between subtypes of the 5-HT1 receptor. European journal of pharmacology, 1988, Nov-22, Volume: 157, Issue:2-3 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Action Potentials; Animals; Anti-Anxiety Agents; Male; Piperazines; Pyrimidines; Quinoxalines; Raphe Nuclei; Rats; Rats, Inbred Strains; Receptors, Serotonin; Substantia Nigra; Tetrahydronaphthalenes	1988
Relationship of increased food intake and plasma ACTH levels to 5-HT1A receptor activation in rats. Psychoneuroendocrinology, 1988, Volume: 13, Issue:6 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenocorticotropic Hormone; Animals; Anti-Anxiety Agents; Body Weight; Brain; Buspirone; Eating; Male; Naphthalenes; Pyrimidines; Rats; Receptors, Serotonin; Tetrahydronaphthalenes	1988
The effects of a 5-HT1 receptor ligand isapirone (TVX Q 7821) on 5-HT synthesis and the behavioural effects of 5-HT agonists in mice and rats. Psychopharmacology, 1986, Volume: 89, Issue:3 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Behavior, Animal; Drug Interactions; Indoles; Male; Methoxydimethyltryptamines; Mice; Mice, Inbred C57BL; Motor Activity; Pyrimidines; Rats; Rats, Inbred Strains; Receptors, Dopamine; Serotonin; Tetrahydronaphthalenes	1986
Inhibitory presynaptic 5-hydroxytryptamine (5-HT) receptors on the sympathetic nerves of the human saphenous vein. Naunyn-Schmiedeberg's archives of pharmacology, 1986, Volume: 332, Issue:4 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adult; Aged; Electric Stimulation; Female; Humans; In Vitro Techniques; Male; Middle Aged; Norepinephrine; Pyrimidines; Receptors, Serotonin; Saphenous Vein; Serotonin; Serotonin Antagonists; Sympathetic Nervous System; Tetrahydronaphthalenes	1986
Differential effects of 5-hydroxytryptamine1a selective drugs on the 5-HT behavioral syndrome. Pharmacology, biochemistry, and behavior, 1986, Volume: 24, Issue:6 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Behavior, Animal; Buspirone; Dose-Response Relationship, Drug; Methoxydimethyltryptamines; Pyrimidines; Rats; Receptors, Serotonin; Serotonin; Tetrahydronaphthalenes; Time Factors	1986
Effect of chronic treatment with 5-HT1 agonist (8-OH-DPAT and RU 24969) and antagonist (isapirone) drugs on the behavioural responses of mice to 5-HT1 and 5-HT2 agonists. British journal of pharmacology, 1986, Volume: 89, Issue:2 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Body Temperature; Brain Chemistry; Indoles; Injections, Intraventricular; Male; Mice; Mice, Inbred C57BL; Motor Activity; Naphthalenes; Pyrimidines; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Tetrahydronaphthalenes	1986
Differential effects of serotonin (5-HT1A and 5-HT2) agonists and antagonists on renin and corticosterone secretion. Neuroendocrinology, 1987, Volume: 45, Issue:4 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Corticosterone; Ergolines; Fenfluramine; Male; Pyrazines; Pyrimidines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Renin; Serotonin; Serotonin Antagonists; Tetrahydronaphthalenes	1987
Effect of serotonin and serotonin analogues on passive membrane properties of lateral septal neurons in vitro. Brain research, 1987, Aug-04, Volume: 417, Issue:1 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Buspirone; Cell Membrane; Electric Conductivity; Fenfluramine; Male; Membrane Potentials; Pyrimidines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Septum Pellucidum; Serotonin; Tetrahydronaphthalenes	1987
Evidence that the putative 5-HT1A receptor agonists, 8-OH-DPAT and ipsapirone, have a central hypotensive action that differs from that of clonidine in anaesthetised cats. European journal of pharmacology, 1987, Jun-19, Volume: 138, Issue:2 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Anesthesia; Animals; Antihypertensive Agents; Atropine; Blood Pressure; Cats; Clonidine; Dioxanes; Heart Rate; Idazoxan; Male; Naphthalenes; Neurons; Pyrimidines; Receptors, Serotonin; Sympathetic Nervous System; Tetrahydronaphthalenes; Trimethaphan; Vagotomy	1987
Blockade of potentiated startle responding in rats by 5-hydroxytryptamine1A receptor ligands. European journal of pharmacology, 1988, Nov-08, Volume: 156, Issue:3 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Buspirone; Male; Methysergide; Naphthalenes; Piperazines; Pyrimidines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Reflex, Startle; Tetrahydronaphthalenes	1988
Anxiolytic effect of the 5-HT1A compounds 8-hydroxy-2-(di-n-propylamino) tetralin and ipsapirone in the social interaction paradigm: evidence of a presynaptic action. Brain research bulletin, 1995, Volume: 37, Issue:2 Topics: 5,7-Dihydroxytryptamine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Analysis of Variance; Animals; Anti-Anxiety Agents; Hippocampus; Injections; Injections, Intraperitoneal; Injections, Intraventricular; Interpersonal Relations; Ligands; Male; Motor Activity; Pyrimidines; Raphe Nuclei; Rats; Rats, Wistar	1995
Action of ipsapirone and 8-OH-DPAT on exploratory behavior in hamsters (Mesocricetus auratus): effects of antagonists and p-CPA. Pharmacology, biochemistry, and behavior, 1995, Volume: 50, Issue:3 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Analysis of Variance; Animals; Anti-Anxiety Agents; Cricetinae; Exploratory Behavior; Fenclonine; Male; Mesocricetus; Pyrimidines; Serotonin Receptor Agonists	1995
Are 5-HT1A autoreceptors involved in the inhibitory effect of ipsapirone on cold-elicited thyrotropin secretion? Neuroendocrinology, 1993, Volume: 57, Issue:4 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Blood Glucose; Cold Temperature; Corticosterone; Fenclonine; Hydroxyindoleacetic Acid; Hypothalamus; Male; Metergoline; Pindolol; Proadifen; Pyrimidines; Rats; Rats, Wistar; Receptors, Serotonin; Serotonin; Thyrotropin	1993
Neurotrophic effects of ipsapirone and other 5-HT1A receptor agonists on septal cholinergic neurons in culture. Brain research. Developmental brain research, 1994, Oct-14, Volume: 82, Issue:1-2 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Acetylcholine; Animals; Autoradiography; Brain; Cell Division; Cells, Cultured; Choline O-Acetyltransferase; Dose-Response Relationship, Drug; Female; Fetus; Immunohistochemistry; Nerve Growth Factors; Neurons; Piperazines; Pregnancy; Propanolamines; Pyrimidines; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Thiophenes; Tritium	1994
Are postsynaptic 5-HT1A receptors involved in the anxiolytic effects of 5-HT1A receptor agonists and in their inhibitory effects on the firing of serotonergic neurons in the rat? The Journal of pharmacology and experimental therapeutics, 1995, Volume: 272, Issue:2 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Anti-Anxiety Agents; Autoreceptors; Corpus Striatum; Hippocampus; Male; Pyrimidines; Raphe Nuclei; Rats; Rats, Wistar; Receptors, Serotonin; Serotonin Receptor Agonists	1995
5-HT1A receptor agonists improve the performance of normal and scopolamine-impaired rats in an operant delayed matching to position task. Psychopharmacology, 1994, Volume: 116, Issue:2 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Conditioning, Operant; Male; Memory, Short-Term; Piperazines; Psychomotor Performance; Pyrimidines; Rats; Rats, Wistar; Scopolamine; Serotonin Antagonists; Serotonin Receptor Agonists; Space Perception	1994
Serotonergic influences on male sexual behavior of rhesus monkeys: effects of serotonin agonists. Psychopharmacology, 1993, Volume: 111, Issue:1 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Copulation; Dose-Response Relationship, Drug; Ejaculation; Macaca mulatta; Male; Piperazines; Pyrimidines; Serotonin; Serotonin Receptor Agonists; Sexual Behavior, Animal	1993
Ipsapirone and 8-OH-DPAT reduce ethanol preference in rats: involvement of presynaptic 5-HT1A receptors. Psychopharmacology, 1993, Volume: 112, Issue:1 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Alcohol Drinking; Animals; Depression, Chemical; Dose-Response Relationship, Drug; Drinking; Eating; Nucleus Accumbens; Pyrimidines; Raphe Nuclei; Rats; Rats, Inbred Strains; Rats, Wistar; Receptors, Presynaptic; Receptors, Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists	1993
Effects of buspirone and ipsapirone on schedule induced polydipsia: comparison with 8-hydroxy-2-(di-n-propylamino)tetralin (8-OH-DPAT) and raclopride. Psychopharmacology, 1993, Volume: 112, Issue:1 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Buspirone; Conditioning, Operant; Dopamine Antagonists; Drinking Behavior; Male; Pyrimidines; Raclopride; Rats; Rats, Sprague-Dawley; Reinforcement Schedule; Salicylamides; Serotonin Receptor Agonists	1993
Effect of acute and repeated administration of 5-HT1A receptor agonists on 5-HT release in rat brain in vivo. Naunyn-Schmiedeberg's archives of pharmacology, 1993, Volume: 348, Issue:4 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic beta-Antagonists; Animals; Brain Chemistry; Buspirone; Dose-Response Relationship, Drug; Electrodes, Implanted; Electrophysiology; Hippocampus; Male; Microdialysis; Pindolol; Pyrimidines; Rats; Rats, Sprague-Dawley; Serotonin; Serotonin Receptor Agonists	1993
Neuronal circuits involved in the anxiolytic effects of the 5-HT1A receptor agonists 8-OH-DPAT ipsapirone and buspirone in the rat. European journal of pharmacology, 1993, Nov-16, Volume: 249, Issue:3 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amygdala; Animals; Anti-Anxiety Agents; Behavior, Animal; Buspirone; Dose-Response Relationship, Drug; Electroshock; Hippocampus; Male; Pyrimidines; Raphe Nuclei; Rats; Rats, Wistar; Receptors, Serotonin; Serotonin Receptor Agonists; Ultrasonics; Vocalization, Animal	1993
Discriminative stimulus effect of flesinoxan: effect of 5-HT1A antagonists and PCPA. Pharmacology, biochemistry, and behavior, 1994, Volume: 47, Issue:4 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Brain; Discrimination Learning; Fenclonine; Male; Pindolol; Piperazines; Pyrimidines; Rats; Rats, Wistar; Receptors, Serotonin, 5-HT1; Serotonin Antagonists; Serotonin Receptor Agonists	1994
Excitation of noradrenergic cell firing by 5-hydroxytryptamine1A agonists correlates with dopamine antagonist properties. The Journal of pharmacology and experimental therapeutics, 1994, Volume: 268, Issue:3 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Buspirone; Dopamine; Dopamine Antagonists; Haloperidol; Locus Coeruleus; Male; Neurons; Norepinephrine; Pyrimidines; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Serotonin; Serotonin Receptor Agonists; Substantia Nigra	1994
Electrophysiological evidence for a large receptor reserve for inhibition of dorsal raphe neuronal firing by 5-HT1A agonists. Synapse (New York, N.Y.), 1993, Volume: 14, Issue:4 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Electrophysiology; Extracellular Space; Male; Microelectrodes; Neurons; Piperazines; Pyrimidines; Quinolines; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists	1993
Effects of selective 5-HT1 receptor agonists in water-deprived rats on salt intake in two-choice tests. Pharmacology, biochemistry, and behavior, 1993, Volume: 45, Issue:3 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Dose-Response Relationship, Drug; Drinking Behavior; Male; Piperazines; Pyrimidines; Rats; Receptors, Serotonin; Serotonin Receptor Agonists; Sodium Chloride; Taste; Water Deprivation	1993
Stimulation of 5-HT1A and 5-HT2/5-HT1C receptors induce oxytocin release in the male rat. Brain research, 1993, May-21, Volume: 611, Issue:2 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Buspirone; Male; Oxytocin; Piperazines; Pyrimidines; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Ritanserin; Serotonin Antagonists; Serotonin Receptor Agonists	1993
Comparative effects of chronic 8-OH-DPAT, gepirone and ipsapirone treatment on the sensitivity of somatodendritic 5-HT1A autoreceptors. Neuropharmacology, 1993, Volume: 32, Issue:6 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Brain; Chromatography, High Pressure Liquid; Dendrites; Dose-Response Relationship, Drug; Male; Pyrimidines; Rats; Rats, Sprague-Dawley; Receptors, Serotonin	1993
Effect of 5-HT-1A receptor agonists on paw licking reaction on hot plate and unpunished drinking in rat. Life sciences, 1993, Volume: 52, Issue:12 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Buspirone; Drinking Behavior; Indoles; Male; Pain; Prosencephalon; Punishment; Pyrimidines; Radioligand Assay; Rats; Rats, Wistar; Receptors, Serotonin; Serotonin Receptor Agonists; Thirst; Time Factors	1993
Studies on the neuronal circuits involved in the discriminative stimulus effects of 5-hydroxytryptamine1A receptor agonists in the rat. The Journal of pharmacology and experimental therapeutics, 1993, Volume: 265, Issue:2 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Discrimination Learning; Hippocampus; Male; Methoxydimethyltryptamines; Neurons; Piperazines; Pyrimidines; Raphe Nuclei; Rats; Rats, Wistar; Receptors, Serotonin	1993
Central 5-HT1A receptors inhibit adrenocortical secretion. Neuroendocrinology, 1993, Volume: 57, Issue:2 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenal Cortex; Anesthesia; Animals; Corticosterone; Injections, Intraventricular; Male; Paraventricular Hypothalamic Nucleus; Piperazines; Pyrimidines; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Serotonin; Serotonin Antagonists	1993
Serotonergic mechanisms involved in the exploratory behaviour of mice in a fully automated two-compartment black and white text box. Pharmacology & toxicology, 1995, Volume: 77, Issue:1 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic beta-Antagonists; Animals; Anti-Anxiety Agents; Anxiety Disorders; Buspirone; Chlordiazepoxide; Darkness; Diazepam; Disease Models, Animal; Exploratory Behavior; Fenfluramine; Light; Male; Mice; Penbutolol; Propanolamines; Pyrimidines; Selective Serotonin Reuptake Inhibitors; Serotonin Antagonists; Serotonin Receptor Agonists	1995
Behavioural response to pharmacologic manipulation of serotonin receptors in the genetically dystonic hamster. Pharmacology, biochemistry, and behavior, 1995, Volume: 52, Issue:4 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Behavior, Animal; Cricetinae; Dystonia; Motor Activity; Pyrimidines; Receptors, Serotonin; Ritanserin; Serotonin Receptor Agonists	1995
Discriminative stimulus effects of the 5HT1A agonist 8-OH-DPAT: attenuation by mu but not by kappa opioids. Psychopharmacology, 1995, Volume: 122, Issue:4 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; 8-Hydroxy-2-(di-n-propylamino)tetralin; Analgesics; Animals; Benzomorphans; Discrimination Learning; Drug Therapy, Combination; Fentanyl; Male; Morphine; Narcotics; Pyrimidines; Pyrrolidines; Rats; Receptors, Opioid, kappa; Receptors, Opioid, mu; Serotonin Receptor Agonists	1995
The role of serotonergic receptors in the effects of mu opioids in squirrel monkeys responding under a titration procedure. Psychopharmacology, 1996, Volume: 126, Issue:1 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Analgesics, Opioid; Analysis of Variance; Animals; Behavior, Animal; Dose-Response Relationship, Drug; Electroshock; Male; Morphine; Pain Measurement; Pyrimidines; Receptors, Opioid, mu; Receptors, Serotonin; Saimiri; Serotonin Antagonists; Serotonin Receptor Agonists	1996
Effects of repeated doses of azapirones on rat brain 5-HT1A receptors and plasma corticosterone levels. General pharmacology, 1996, Volume: 27, Issue:2 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Brain; Buspirone; Calcium; Corticosterone; Dose-Response Relationship, Drug; Hypothalamo-Hypophyseal System; Neurons; Pituitary-Adrenal System; Pyrimidines; Raphe Nuclei; Rats; Receptors, Serotonin; Serotonin Receptor Agonists	1996
5-HT1A agonists induce hippocampal theta activity in freely moving cats: role of presynaptic 5-HT1A receptors. Brain research, 1996, Nov-11, Volume: 739, Issue:1-2 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Action Potentials; Analysis of Variance; Animals; Cats; Electroencephalography; Hippocampus; Male; Movement; Neurons; Piperazines; Pyrimidines; Receptors, Serotonin; Serotonin Receptor Agonists; Sleep, REM; Theta Rhythm	1996
The putative 5-HT1A receptor antagonist DU125530 blocks the discriminative stimulus of the 5-HT1A receptor agonist flesinoxan in pigeons. European journal of pharmacology, 1997, May-01, Volume: 325, Issue:2-3 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Buspirone; Columbidae; Discrimination Learning; Fluvoxamine; Indoles; Pindolol; Piperazines; Pyridines; Pyrimidines; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Antagonists; Serotonin Receptor Agonists; Thiazoles	1997
Studies on the sites and mechanisms of 5-HT1A receptor-mediated in vivo actions. Acta physiologica Hungarica, 1996, Volume: 84, Issue:4 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Body Temperature; Hormones; Injections, Intravenous; Injections, Intraventricular; Male; Paraventricular Hypothalamic Nucleus; Pyrimidines; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Serotonin Receptor Agonists	1996
Modification of the anxiolytic action of 5-HT1A compounds by GABA-benzodiazepine agents in rats. Pharmacology, biochemistry, and behavior, 1998, Volume: 60, Issue:1 Topics: 5-Methoxytryptamine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Anti-Anxiety Agents; Anxiety; Bicuculline; Buspirone; Diazepam; Drug Interactions; Flumazenil; GABA Agonists; Male; Psychomotor Performance; Pyrimidines; Rats; Rats, Wistar; Receptors, Serotonin; Receptors, Serotonin, 5-HT1	1998
Neuroprotection against N-methyl-D-aspartate-induced excitotoxicity in rat magnocellular nucleus basalis by the 5-HT1A receptor agonist 8-OH-DPAT. European journal of pharmacology, 1998, Oct-02, Volume: 358, Issue:2 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Acetylcholinesterase; Animals; Excitatory Amino Acid Agonists; Male; N-Methylaspartate; Neuroprotective Agents; Pyrimidines; Rats; Rats, Wistar; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Receptor Agonists; Substantia Innominata	1998
Functional characteristics of a series of N4-substituted 1-(2,3-dihydro-1,4-benzodioxin-5-yl)piperazines as 5-HT1A receptor ligands. Structure-activity relationships. Bioorganic & medicinal chemistry letters, 1998, Sep-22, Volume: 8, Issue:18 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adenylyl Cyclases; Animals; CHO Cells; Cricetinae; Frontal Lobe; Humans; Ligands; Models, Chemical; Piperazines; Pyridines; Pyrimidines; Rats; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Antagonists; Serotonin Receptor Agonists; Structure-Activity Relationship	1998
Selective antiaggressive effects of alnespirone in resident-intruder test are mediated via 5-hydroxytryptamine1A receptors: A comparative pharmacological study with 8-hydroxy-2-dipropylaminotetralin, ipsapirone, buspirone, eltoprazine, and WAY-100635. The Journal of pharmacology and experimental therapeutics, 1999, Volume: 288, Issue:3 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aggression; Animals; Behavior, Animal; Buspirone; Male; Piperazines; Pyridines; Pyrimidines; Rats; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Antagonists; Serotonin Receptor Agonists; Spiro Compounds	1999
[Effects of 5-HT1a serotonin receptor agonists on sex motivation in male mice]. Biulleten' eksperimental'noi biologii i meditsiny, 1999, Volume: 127, Issue:2 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Estrus; Female; Male; Mice; Mice, Inbred CBA; Motivation; Piperazines; Pyrimidines; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Receptor Agonists; Sexual Behavior, Animal; Testosterone	1999
Blockade of the anxiolytic-like action of ipsapirone and buspirone, but not that of 8-OH-DPAT, by adrenalectomy in male rats. Psychoneuroendocrinology, 1999, Volume: 24, Issue:4 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenal Medulla; Adrenalectomy; Animals; Anti-Anxiety Agents; Behavior, Animal; Buspirone; Male; Motor Activity; Pyrimidines; Rats; Rats, Wistar; Serotonin Agents	1999
Comparative effects of serotonergic agonists with varying efficacy at the 5-HT(1A) receptor on core body temperature: modification by the selective 5-HT(1A) receptor antagonist WAY 100635. Journal of psychopharmacology (Oxford, England), 1999, Volume: 13, Issue:3 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Body Temperature; Dose-Response Relationship, Drug; Hypothermia; Male; Piperazines; Pyridines; Pyrimidines; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Antagonists; Serotonin Receptor Agonists	1999
5-hydroxytryptamine (5-HT)1A autoreceptor adaptive changes in substance P (neurokinin 1) receptor knock-out mice mimic antidepressant-induced desensitization. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2001, Oct-15, Volume: 21, Issue:20 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antidepressive Agents; Autoreceptors; Drug Resistance; Electrophysiology; Immunohistochemistry; In Vitro Techniques; Male; Mice; Mice, Knockout; Neurons; Paroxetine; Piperazines; Pyridines; Pyrimidines; Raphe Nuclei; Receptors, Neurokinin-1; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; RNA, Messenger; Selective Serotonin Reuptake Inhibitors; Serotonin Antagonists; Serotonin Receptor Agonists; Substance P	2001
The 5-HT1A receptor and the stimulus effects of LSD in the rat. Psychopharmacology, 2005, Volume: 182, Issue:2 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Buspirone; Dose-Response Relationship, Drug; Lysergic Acid Diethylamide; Male; Piperazines; Pyridines; Pyrimidines; Rats; Rats, Inbred F344; Receptor, Serotonin, 5-HT1A; Serotonin 5-HT1 Receptor Agonists	2005