8-hydroxy-2-(di-n-propylamino)tetralin has been researched along with guanosine triphosphate in 29 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (24.14) | 18.7374 |
| 1990's | 19 (65.52) | 18.2507 |
| 2000's | 3 (10.34) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Newman-Tancredi, A; Strange, PG; Wootton, R | 1 |
| Osborne, NN | 1 |
| Gross, G; Hanft, G; Schüttler, K; Xin, X | 1 |
| Hashimoto, T; Nakai, H; Nishino, N; Tanaka, C | 1 |
| Emerit, MB; Gozlan, H; Hamon, M; Miquel, MC | 1 |
| Deliganis, AV; Peroutka, SJ; Pierce, PA | 1 |
| Antón-Tay, F; Benítez-King, G; Chávez, JL; Hong, E; Martínez, I | 1 |
| Brown, CM; Kilpatrick, AT; MacKinnon, AC; McGrath, JC; Spedding, M | 1 |
| Harrington, MA; Peroutka, SJ | 1 |
| Imai, S; Kitamura, Y; Matsueda, R; Nomura, Y | 1 |
| Hayakawa, H; Sarai, K; Yamawaki, S; Yokota, N; Yoshida, R | 1 |
| Hirose, A; Kumasaka, Y; Nakamura, M; Shimizu, H; Tanaka, H; Tatsuno, T | 1 |
| Balestre, MN; Bockaert, J; Cory, RN; Guillon, G; Rouot, B; Sladeczek, F | 1 |
| Lambert, G; Monroe, PJ; Nelson, DL; Yamamura, HI | 1 |
| Oksenberg, D; Peroutka, SJ | 1 |
| Peroutka, SJ; Schlegel, JR | 1 |
| el Mestikawy, S; Emerit, MB; Gozlan, H; Hall, MD; Hamon, M; Pichat, L | 1 |
| Gower, AJ; Kendall, DA; Marsden, CA; Robson, L | 1 |
| Burris, KD; Butkerait, P; Graham, TE; Hallak, H; Manning, DR; Miller, HA; Molinoff, PB; Zheng, Y | 1 |
| Fuxe, K; Odagaki, Y | 1 |
| Fujiwara, Y; Hamagishi, Y; Hikiji, M; Kashihara, K; Ohnuki, T; Oki, T; Otsuki, S; Roeske, WR; Sora, I; Tomita, H | 1 |
| Bockaert, J; Harris, B; Jouin, P; Le Nguyen, D; McClue, S; Varrault, A | 1 |
| Newman-Tancredi, A; Strange, PG; Sundaram, H | 1 |
| Childers, SR; Sim, LJ; Xiao, R | 1 |
| Boni, C; Fabre, V; Hamon, M; Laporte, AM; Lesourd, M; Mocaër, E | 1 |
| Draguhn, A; Empson, RM; Gloveli, T; Heinemann, U; Schmitz, D | 1 |
| Hillefors, M; von Euler, G | 1 |
| Dewael, Y; Grillner, S; Hill, RH; Svensson, E | 1 |
| Lin, H; Saisch, SG; Strange, PG | 1 |
29 other study(ies) available for 8-hydroxy-2-(di-n-propylamino)tetralin and guanosine triphosphate
| Article | Year |
|---|---|
High-level stable expression of recombinant 5-HT1A 5-hydroxytryptamine receptors in Chinese hamster ovary cells.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adenylyl Cyclases; Animals; Binding, Competitive; Blotting, Northern; Cattle; Cell Membrane; CHO Cells; Colforsin; Cricetinae; Gene Expression; Guanosine Triphosphate; Hippocampus; Humans; Receptors, Serotonin; Recombinant Proteins; Tetrahydronaphthalenes; Transfection | 1992 |
Effects of GTP, forskolin, sodium fluoride, serotonin, dopamine, and carbachol on adenylate cyclase in Teleost retina.
Topics: 1-Methyl-3-isobutylxanthine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Adenylate Cyclase Toxin; Adenylyl Cyclases; Animals; Atropine; Carbachol; Colforsin; Cyclic AMP; Dopamine; Drug Synergism; Fishes; GTP-Binding Proteins; Guanosine Triphosphate; Pertussis Toxin; Retina; Serotonin; Sodium Fluoride; Tetrahydronaphthalenes; Virulence Factors, Bordetella | 1990 |
Urapidil analogues are potent ligands of the 5-HT1A receptor.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Cerebral Cortex; Guanosine Triphosphate; In Vitro Techniques; Ligands; Male; Piperazines; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Serotonin; Serotonin Antagonists; Tetrahydronaphthalenes | 1990 |
Increase in serotonin 5-HT1A receptors in prefrontal and temporal cortices of brains from patients with chronic schizophrenia.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aged; Binding, Competitive; Cell Membrane; Cerebral Cortex; Female; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Hippocampus; Humans; Kinetics; Male; Middle Aged; Receptors, Serotonin; Reference Values; Schizophrenia; Serotonin Antagonists; Temporal Lobe; Tetrahydronaphthalenes | 1991 |
The GTP-insensitive component of high-affinity [3H]8-hydroxy-2-(di-n-propylamino)tetralin binding in the rat hippocampus corresponds to an oxidized state of the 5-hydroxytryptamine1A receptor.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Binding, Competitive; Dithiothreitol; Ethylmaleimide; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Hippocampus; Male; Oxidation-Reduction; Rats; Receptors, Serotonin; Serotonin Antagonists; Tetrahydronaphthalenes; Tetrathionic Acid; Tritium | 1991 |
Differential interactions of dimethyltryptamine (DMT) with 5-HT1A and 5-HT2 receptors.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adenylyl Cyclases; Animals; Binding, Competitive; Cerebral Cortex; Dose-Response Relationship, Drug; Guanosine Triphosphate; Ketanserin; N,N-Dimethyltryptamine; Phosphatidylinositols; Radioligand Assay; Rats; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Tetrahydronaphthalenes | 1991 |
Further evidence that indorenate is a 5-HT1 agonist.
Topics: 5-Methoxytryptamine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antihypertensive Agents; Binding, Competitive; Guanosine Triphosphate; Hippocampus; In Vitro Techniques; Male; Membranes; Potassium; Pyrimidines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Tetrahydronaphthalenes | 1991 |
Heterogeneity of alpha 2-adrenoceptors in rat cortex but not human platelets can be defined by 8-OH-DPAT, RU 24969 and methysergide.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Binding, Competitive; Blood Platelets; Cerebral Cortex; Guanosine Triphosphate; In Vitro Techniques; Indoles; Kinetics; Male; Methysergide; Naphthalenes; Oxymetazoline; Prazosin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Species Specificity; Tetrahydronaphthalenes; Yohimbine | 1990 |
Modulation of 5-hydroxytryptamine1A receptor density by nonhydrolyzable GTP analogues.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adenosine Triphosphate; Animals; Cell Membrane; Cerebral Cortex; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Guanylyl Imidodiphosphate; Kinetics; Models, Theoretical; Rats; Receptors, Serotonin; Tetrahydronaphthalenes; Thionucleotides | 1990 |
Effects of sulfhydryl-modifying reagents, 3-nitro-2-pyridinesulfenyl compounds, on the coupling between inhibitory receptors and GTP-binding proteins Gi/Go in rat brain membranes.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Brain; Cell Membrane; Clonidine; Cysteine; Ethylmaleimide; GTP-Binding Proteins; Guanosine Triphosphate; Indicators and Reagents; Male; Nitro Compounds; Pertussis Toxin; Pyridines; Rats; Receptors, Adrenergic, alpha; Receptors, Serotonin; Sulfhydryl Compounds; Tetrahydronaphthalenes; Virulence Factors, Bordetella | 1990 |
[Multiple [3H]8-hydroxy-2-(di-n-propylamino)-tetralin binding sites in rat brain: modulation by GTP and cations].
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Binding Sites; Biogenic Monoamines; Brain; Cations; Clomipramine; GTP-Binding Proteins; Guanosine Triphosphate; Humans; Male; Naphthalenes; Rats; Rats, Inbred Strains; Tetrahydronaphthalenes | 1989 |
Characterization of the putative anxiolytic SM-3997 recognition sites in rat brain.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Binding, Competitive; Brain; Cations, Divalent; Cell Membrane; Edetic Acid; Guanosine Triphosphate; Hippocampus; Isoindoles; Kinetics; Male; Neurotransmitter Agents; Piperazines; Pyrimidines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin; Sodium; Tetrahydronaphthalenes; Tissue Distribution | 1988 |
The 5-hydroxytryptamine (5-HT2) receptor stimulates inositol phosphate formation in intact and broken WRK1 cells: determination of occupancy-response relationships for 5-HT agonists.
Topics: 5-Methoxytryptamine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Bufotenin; Cell Line; Dibenzylchlorethamine; Dose-Response Relationship, Drug; GTP-Binding Proteins; Guanosine Triphosphate; Indoles; Inositol Phosphates; Kinetics; Mammary Neoplasms, Experimental; Mathematics; N,N-Dimethyltryptamine; Piperazines; Quipazine; Rats; Receptors, Serotonin; Sugar Phosphates; Tetrahydronaphthalenes; Tryptamines | 1987 |
[3H]spiroxatrine labels a serotonin1A-like site in the rat hippocampus.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Binding, Competitive; Cell Membrane; Dioxanes; Dioxins; Dopamine; Guanosine Triphosphate; Haloperidol; Hippocampus; Male; Norepinephrine; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin; Spiperone; Spiro Compounds; Tetrahydronaphthalenes; Tritium | 1987 |
Antagonism of 5-hydroxytryptamine1A (5-HT1A) receptor-mediated modulation of adenylate cyclase activity by pindolol and propranolol isomers.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adenylyl Cyclases; Animals; Colforsin; GTP-Binding Proteins; Guanosine Triphosphate; Hippocampus; In Vitro Techniques; Pindolol; Propranolol; Rats; Receptors, Serotonin; Serotonin Antagonists; Stereoisomerism; Tetrahydronaphthalenes | 1988 |
Nucleotide interactions with 5-HT1A binding sites directly labeled by [3H]-8-hydroxy-2-(DI-n-propylamino)tetralin ([3H]-8-OH-DPAT).
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adenylyl Cyclases; Animals; Binding, Competitive; Brain; Guanine Nucleotides; Guanosine Diphosphate; Guanosine Monophosphate; Guanosine Triphosphate; In Vitro Techniques; Kinetics; Naphthalenes; Rats; Receptors, Serotonin; Tetrahydronaphthalenes; Tritium | 1986 |
Differentiation of pre- and post-synaptic high affinity serotonin receptor binding sites using physico-chemical parameters and modifying agents.
Topics: 5,7-Dihydroxytryptamine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Cerebral Cortex; Corpus Striatum; Guanosine Triphosphate; Hippocampus; Hydrogen-Ion Concentration; Kinetics; Male; Manganese; Naphthalenes; Rats; Rats, Inbred Strains; Receptors, Neurotransmitter; Receptors, Serotonin; Sulfhydryl Reagents; Temperature; Tetrahydronaphthalenes | 1986 |
Age-related behavioural, neurochemical and radioligand binding changes in the central 5-HT system of Sprague-Dawley rats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aging; Amphetamines; Animals; Behavior, Animal; Binding, Competitive; Brain Chemistry; Dose-Response Relationship, Drug; Guanosine Triphosphate; Hydroxyindoleacetic Acid; Ketanserin; Male; Radioligand Assay; Rats; Rats, Sprague-Dawley; Serotonin; Serotonin Receptor Agonists | 1993 |
Expression of the human 5-hydroxytryptamine1A receptor in Sf9 cells. Reconstitution of a coupled phenotype by co-expression of mammalian G protein subunits.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amino Acid Sequence; Aminopyridines; Animals; Baculoviridae; Base Sequence; Cell Line; GTP-Binding Proteins; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Humans; Molecular Sequence Data; Peptide Fragments; Piperazines; Protein Processing, Post-Translational; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Recombinant Proteins; Signal Transduction; Spodoptera | 1995 |
5-HT1A receptor-mediated activation of high-affinity GTPase in rat hippocampal membranes.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Dose-Response Relationship, Drug; Enzyme Activation; GTP Phosphohydrolases; GTP-Binding Proteins; Guanosine Triphosphate; Hippocampus; In Vitro Techniques; Male; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Serotonin | 1995 |
Characterization of a cloned rat serotonin 5-HT1A receptor expressed in the HeLa cell line.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antipsychotic Agents; Binding, Competitive; Cloning, Molecular; Guanosine Triphosphate; HeLa Cells; Humans; Rats; Receptors, Serotonin; Serotonin Receptor Agonists; Spiperone; Transfection | 1993 |
5-Hydroxytryptamine1A receptor synthetic peptides. Mechanisms of adenylyl cyclase inhibition.
Topics: 3T3 Cells; 8-Hydroxy-2-(di-n-propylamino)tetralin; Adenylate Cyclase Toxin; Adenylyl Cyclase Inhibitors; Amino Acid Sequence; Animals; Cell Line; Cell Membrane; Clone Cells; Colforsin; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Hippocampus; Humans; Kinetics; Male; Mice; Molecular Sequence Data; Moths; Peptide Fragments; Pertussis Toxin; Protein Structure, Secondary; Rats; Rats, Wistar; Receptors, Serotonin; Virulence Factors, Bordetella | 1994 |
Characterization of recombinant human serotonin 5HT1A receptors expressed in Chinese hamster ovary cells. [3H]spiperone discriminates between the G-protein-coupled and -uncoupled forms.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; CHO Cells; Cricetinae; GTP-Binding Proteins; Guanosine Triphosphate; Humans; Radioligand Assay; Receptors, Serotonin; Recombinant Proteins; Serotonin Antagonists; Spiperone; Tritium | 1993 |
In vitro autoradiographic localization of 5-HT1A receptor-activated G-proteins in the rat brain.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Autoradiography; Brain; Brain Mapping; Dose-Response Relationship, Drug; GTP-Binding Proteins; Guanosine Triphosphate; In Vitro Techniques; Male; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Serotonin Receptor Agonists | 1997 |
[3H]Alnespirone: a novel specific radioligand of 5-HT1A receptors in the rat brain.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Anti-Anxiety Agents; Autoradiography; Brain; Chlorides; Ethylmaleimide; Guanosine Triphosphate; Hydrogen-Ion Concentration; Ligands; Male; Manganese Compounds; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Receptor Agonists; Spiro Compounds; Temperature | 1997 |
Serotonin reduces synaptic excitation in the superficial medial entorhinal cortex of the rat via a presynaptic mechanism.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Bicuculline; Entorhinal Cortex; Excitatory Postsynaptic Potentials; Female; Guanosine Triphosphate; Hippocampus; In Vitro Techniques; Male; Patch-Clamp Techniques; Piperazines; Potassium Channels; Rats; Rats, Wistar; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Spiperone; Synapses; Synaptic Transmission; Tetrodotoxin | 1998 |
Pharmacology of [3H]R(+)-7-OH-DPAT binding in the rat caudate-putamen.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Benzopyrans; Binding, Competitive; Caudate Nucleus; Clozapine; Dopamine; Dopamine Agonists; Dopamine Antagonists; Guanidines; Guanosine Triphosphate; Haloperidol; Heterotrimeric GTP-Binding Proteins; Indans; Kinetics; Magnesium; Male; Oxazines; Protein Binding; Putamen; Quinpirole; Raclopride; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; Receptors, Dopamine D3; Remoxipride; Sodium; Specific Pathogen-Free Organisms; Sulfones; Sulpiride; Tetrahydronaphthalenes | 2001 |
5-HT inhibits N-type but not L-type Ca(2+) channels via 5-HT1A receptors in lamprey spinal neurons.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Anesthetics, Local; Animals; Cadmium; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Channels, N-Type; Cells, Cultured; Drug Interactions; Electric Conductivity; Free Radical Scavengers; Guanosine Triphosphate; Lampreys; Larva; Membrane Potentials; Neurons; omega-Conotoxin GVIA; Patch-Clamp Techniques; Pertussis Toxin; Potassium Channel Blockers; Receptor, Serotonin, 5-HT1A; Serotonin; Serotonin Receptor Agonists; Spinal Cord; Tetraethylammonium; Tetrodotoxin; Time Factors | 2003 |
Assays for enhanced activity of low efficacy partial agonists at the D(2) dopamine receptor.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; CHO Cells; Cricetinae; Dopamine Agonists; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Meglumine; Receptors, Dopamine D2; Sodium | 2006 |