Compounds > 8-hydroxy-2-(di-n-propylamino)tetralin

8-hydroxy-2-(di-n-propylamino)tetralin and guanosine diphosphate

8-hydroxy-2-(di-n-propylamino)tetralin has been researched along with guanosine diphosphate in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19901 (12.50)18.7374
1990's2 (25.00)18.2507
2000's5 (62.50)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Peroutka, SJ; Schlegel, JR1
Colpaert, FC; Pauwels, PJ; Tardif, S; Wurch, T1
Dun, NJ; Hwang, LL1
McLoughlin, DJ; Strange, PG1
Carr, IC; Milligan, G; Welsby, PJ; Wilkinson, G1
Morales, M; Oz, M; Rotondo, A; Sun, H; Zhang, L1
Odagaki, Y; Toyoshima, R1
Alper, RH; Raddatz, R1

Other Studies

8 other study(ies) available for 8-hydroxy-2-(di-n-propylamino)tetralin and guanosine diphosphate

ArticleYear
Nucleotide interactions with 5-HT1A binding sites directly labeled by [3H]-8-hydroxy-2-(DI-n-propylamino)tetralin ([3H]-8-OH-DPAT).
    Biochemical pharmacology, 1986, Jun-15, Volume: 35, Issue:12

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adenylyl Cyclases; Animals; Binding, Competitive; Brain; Guanine Nucleotides; Guanosine Diphosphate; Guanosine Monophosphate; Guanosine Triphosphate; In Vitro Techniques; Kinetics; Naphthalenes; Rats; Receptors, Serotonin; Tetrahydronaphthalenes; Tritium

1986
Stimulated [35S]GTP gamma S binding by 5-HT1A receptor agonists in recombinant cell lines. Modulation of apparent efficacy by G-protein activation state.
    Naunyn-Schmiedeberg's archives of pharmacology, 1997, Volume: 356, Issue:5

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Binding, Competitive; Cell Line; Cell Membrane; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; HeLa Cells; Humans; Ligands; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Receptor Agonists

1997
5-Hydroxytryptamine responses in immature rat rostral ventrolateral medulla neurons in vitro.
    Journal of neurophysiology, 1998, Volume: 80, Issue:3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Dopamine Antagonists; Dose-Response Relationship, Drug; GTP-Binding Proteins; Guanosine Diphosphate; Ketanserin; Medulla Oblongata; Membrane Potentials; Neurons; Organ Culture Techniques; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Spiperone; Synaptic Transmission; Thionucleotides

1998
Mechanisms of agonism and inverse agonism at serotonin 5-HT1A receptors.
    Journal of neurochemistry, 2000, Volume: 74, Issue:1

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; CHO Cells; Cricetinae; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Osmolar Concentration; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Receptor Agonists; Sodium

2000
Regulation of the avidity of ternary complexes containing the human 5-HT(1A) receptor by mutation of a receptor contact site on the interacting G protein alpha subunit.
    British journal of pharmacology, 2002, Volume: 137, Issue:3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adenylyl Cyclases; Aminopyridines; Cell Line; Glycine; Guanosine Diphosphate; Heterotrimeric GTP-Binding Proteins; Humans; Isoleucine; Ligands; Mutation; Piperazines; Radioligand Assay; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Recombinant Fusion Proteins; Serotonin Receptor Agonists; Suramin

2002
Direct activation by dopamine of recombinant human 5-HT1A receptors: comparison with human 5-HT2C and 5-HT3 receptors.
    Synapse (New York, N.Y.), 2003, Dec-15, Volume: 50, Issue:4

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Analysis of Variance; Animals; Chelating Agents; CHO Cells; Colforsin; Cricetinae; Cyclic AMP; Dopamine; Dopamine Antagonists; Dose-Response Relationship, Drug; Drug Interactions; Egtazic Acid; Female; G Protein-Coupled Inwardly-Rectifying Potassium Channels; Guanosine Diphosphate; Haloperidol; Humans; Indazoles; Inhibitory Concentration 50; Membrane Potentials; Microinjections; Oocytes; Patch-Clamp Techniques; Pertussis Toxin; Piperazine; Piperazines; Potassium Channels; Potassium Channels, Inwardly Rectifying; Pyridines; Radioligand Assay; Receptor, Serotonin, 5-HT1A; Receptors, Serotonin, 5-HT2; Receptors, Serotonin, 5-HT3; Recombinant Proteins; RNA, Messenger; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Spiperone; Thionucleotides; Tropanes; Xenopus laevis

2003
5-HT1A receptor-mediated G protein activation assessed by [35S]GTPgammaS binding in rat cerebral cortex.
    European journal of pharmacology, 2005, Oct-03, Volume: 521, Issue:1-3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Binding, Competitive; Cell Membrane; Cerebral Cortex; Dose-Response Relationship, Drug; Enzyme Activation; GTP Phosphohydrolases; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Hippocampus; Magnesium Chloride; Male; Piperazines; Pyridines; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1A; Serotonin; Serotonin 5-HT1 Receptor Agonists; Serotonin 5-HT1 Receptor Antagonists; Serotonin Antagonists; Serotonin Receptor Agonists; Sodium Chloride; Sulfur Radioisotopes

2005
Agonist-stimulated [35S]GTPĪ³S binding.
    Current protocols in pharmacology, 2007, Volume: Chapter 2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Hippocampus; Rats; Receptor, Serotonin, 5-HT1A; Sulfur Radioisotopes

2007