Compounds > 8-hydroxy-2-(di-n-propylamino)tetralin

8-hydroxy-2-(di-n-propylamino)tetralin and gr 127935

8-hydroxy-2-(di-n-propylamino)tetralin has been researched along with gr 127935 in 29 studies

Research

Studies (29)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's12 (41.38)18.2507
2000's14 (48.28)29.6817
2010's3 (10.34)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gommeren, W; Haegeman, G; Heylen, L; Lesage, AS; Leysen, JE; Luyten, WH; Schotte, A; Van de Weyer, I; Van Gompel, P; Vanhoenacker, P; Wouters, R1
Maura, G; Raiteri, M1
Bobirnac, I; Schoeffter, P1
Crick, H; Manuel, NA; Wallis, DI1
Clarke, T; Rollema, H; Schulz, DW; Sprouse, JS1
Macor, JE; Mansbach, RS; Rovetti, CC1
Audinot, V; Cistarelli, L; Gobert, A; Millan, MJ; Newman-Tancredi, A; Rivet, JM1
Koob, GF; Parsons, LH; Weiss, F1
Aguerre, S; Chaouloff, F; Mormede, P1
Grailhe, R; Hen, R; Moskowitz, MA; Waeber, C; Yu, XJ1
Cohen, ML; Hemrick-Luecke, SH; Schenck, KW1
Belknap, JK; Hain, HS; Mogil, JS1
Dunn, AJ; Swiergiel, AH1
Lutz, EA; Shannon, HE1
Boers, PM; Donaldson, C; Lambert, GA; Zagami, AS1
Dremencov, E; Garcia, F; Gur, E; Lerer, B; Newman, ME; Van de Kar, LD2
Davidson, C; Hopwood, SE; McLaughlin, DP; Stamford, JA1
Dremencov, E; Gur, E; Lerer, B; Newman, ME2
Conway, MW; O'Neill, MF1
Honda, M; Ono, H1
Dremencov, E; Gur, E; Lerer, B; Newman, ME; Van De Kar, LD1
Azampanah, A; Fletcher, PJ; Korth, KM1
Avraham, Y; Berry, EM; Dremencov, E; Gur, E; Newman, ME1
Ansorge, M; Dulawa, SC; Geyer, MA; Gingrich, JA; Hen, R; Holick Pierz, KA; Masten, VL; Shanahan, NA; Waeber, C1
Jiang, Z; Shang, J; Wang, W; Zhang, H; Zhang, L1
Khatri, N; Lin, RC; Paul, IA; Simpson, KL1
Aronsen, D; Bukholt, N; Foote, J; Highgate, Q; Schenk, S; Van de Wetering, R; Webster, J1

Reviews

1 review(s) available for 8-hydroxy-2-(di-n-propylamino)tetralin and gr 127935

ArticleYear
Control of dorsal raphé 5-HT function by multiple 5-HT(1) autoreceptors: parallel purposes or pointless plurality?
    Trends in neurosciences, 2000, Volume: 23, Issue:10

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antidepressive Agents, Second-Generation; Autoreceptors; Dimerization; Guinea Pigs; Humans; Ion Channels; Ion Transport; Mice; Nerve Tissue Proteins; Neurons; Oxadiazoles; Piperazines; Protein Isoforms; Pyridines; Pyrimidines; Raphe Nuclei; Rats; Receptor, Serotonin, 5-HT1B; Receptor, Serotonin, 5-HT1D; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Second Messenger Systems; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Receptor Agonists; Spiperone; Sumatriptan

2000

Other Studies

28 other study(ies) available for 8-hydroxy-2-(di-n-propylamino)tetralin and gr 127935

ArticleYear
Alniditan, a new 5-hydroxytryptamine1D agonist and migraine-abortive agent: ligand-binding properties of human 5-hydroxytryptamine1D alpha, human 5-hydroxytryptamine1D beta, and calf 5-hydroxytryptamine1D receptors investigated with [3H]5-hydroxytryptamin
    Molecular pharmacology, 1996, Volume: 50, Issue:6

    Topics: Animals; Benzopyrans; Cattle; Cloning, Molecular; Glioma; HeLa Cells; Humans; Mice; Migraine Disorders; Propylamines; Protein Binding; Pyrimidines; Radioligand Assay; Receptors, Serotonin; Serotonin Receptor Agonists; Signal Transduction; Tritium; Tumor Cells, Cultured; Vasoconstrictor Agents

1996
Serotonin 5-HT1D and 5-HT1A receptors respectively mediate inhibition of glutamate release and inhibition of cyclic GMP production in rat cerebellum in vitro.
    Journal of neurochemistry, 1996, Volume: 66, Issue:1

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Afferent Pathways; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cerebellum; Cyclic GMP; Glutamic Acid; Male; N-Methylaspartate; Oxadiazoles; Piperazines; Potassium; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1D; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin; Serotonin Agents; Signal Transduction; Sumatriptan; Synapses; Synaptic Transmission

1996
5-Hydroxytryptamine 5-HT1D receptors mediating inhibition of cyclic AMP accumulation in Madin-Darby canine kidney (MDCK) cells.
    Naunyn-Schmiedeberg's archives of pharmacology, 1995, Volume: 352, Issue:3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Alprostadil; Animals; Cells, Cultured; Cyclic AMP; Dogs; Dose-Response Relationship, Drug; Drug Interactions; Epithelial Cells; Epithelium; Ketanserin; Kidney Cortex; Methiothepin; Oxadiazoles; Pertussis Toxin; Piperazines; Propranolol; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Structure-Activity Relationship; Sumatriptan; Virulence Factors, Bordetella; Yohimbine

1995
Ketanserin-sensitive depressant actions of 5-HT receptor agonists in the neonatal rat spinal cord.
    British journal of pharmacology, 1995, Volume: 116, Issue:6

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Animals, Newborn; Depression, Chemical; Dioxanes; Dopamine Antagonists; Drug Interactions; Female; Ketanserin; Male; Motor Neurons; Oxadiazoles; Pindolol; Piperazines; Propranolol; Rats; Rats, Wistar; Receptors, Serotonin; Reflex, Monosynaptic; Serotonin; Serotonin Antagonists; Spinal Cord; Spiro Compounds; Sumatriptan

1995
Combined administration of a 5-hydroxytryptamine (5-HT)1D antagonist and a 5-HT reuptake inhibitor synergistically increases 5-HT release in guinea pig hypothalamus in vivo.
    Journal of neurochemistry, 1996, Volume: 67, Issue:5

    Topics: 1-Naphthylamine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Drug Synergism; Guinea Pigs; Hydroxyindoleacetic Acid; Hypothalamus; Indoles; Kinetics; Neurons; Oxadiazoles; Piperazines; Pyridines; Receptor, Serotonin, 5-HT1D; Receptors, Serotonin; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Antagonists; Sertraline

1996
CP-135,807, a selective 5-HT1D agonist: effects in drug discrimination and punishment procedures in the pigeon.
    Psychopharmacology, 1996, Volume: 128, Issue:3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Behavior, Animal; Columbidae; Conditioning, Operant; Discrimination Learning; Discrimination, Psychological; Dose-Response Relationship, Drug; Indoles; Male; Oxadiazoles; Piperazines; Punishment; Pyridines; Receptors, Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists

1996
Simultaneous quantification of serotonin, dopamine and noradrenaline levels in single frontal cortex dialysates of freely-moving rats reveals a complex pattern of reciprocal auto- and heteroreceptor-mediated control of release.
    Neuroscience, 1998, Volume: 84, Issue:2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Benzopyrans; Dopamine; Dopamine Agonists; Frontal Lobe; Guanabenz; Guinea Pigs; Homeostasis; Idazoxan; Imidazoles; Indoles; Isoindoles; Male; Medetomidine; Models, Neurological; Motor Activity; Norepinephrine; Oxadiazoles; Piperazines; Prazosin; Raclopride; Rats; Rats, Wistar; Receptors, Adrenergic; Receptors, Dopamine; Receptors, Serotonin; Salicylamides; Serotonin

1998
Serotonin1B receptor stimulation enhances cocaine reinforcement.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1998, Dec-01, Volume: 18, Issue:23

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aminopyridines; Animals; Cocaine; Cocaine-Related Disorders; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Indoles; Injections, Intraventricular; Male; Oxadiazoles; Piperazines; Pyridines; Pyrroles; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT1B; Receptors, Serotonin; Self Administration; Serotonin Antagonists; Serotonin Receptor Agonists

1998
GR 127935 and (+)-WAY 100135 do not affect TFMPP-induced inhibition of 5-HT synthesis in the midbrain and hippocampus of Wistar-Kyoto rats.
    Neuropharmacology, 1998, Volume: 37, Issue:9

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Antagonists; Adrenergic Uptake Inhibitors; Animals; Hippocampus; Idazoxan; Ketanserin; Male; Mesencephalon; Mianserin; Nerve Endings; Oxadiazoles; Piperazines; Rats; Rats, Inbred WKY; Rats, Wistar; Reserpine; Serotonin; Serotonin Agents; Serotonin Antagonists; Serotonin Receptor Agonists; Species Specificity; Tryptophan Hydroxylase

1998
Putative 5-ht5 receptors: localization in the mouse CNS and lack of effect in the inhibition of dural protein extravasation.
    Annals of the New York Academy of Sciences, 1998, Dec-15, Volume: 861

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Autoradiography; Binding Sites; Blood Proteins; Brain; Crosses, Genetic; Female; Lysergic Acid Diethylamide; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Organ Specificity; Oxadiazoles; Piperazines; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Trigeminal Ganglion; Tritium

1998
5-Hydroxytryptamine(1A) receptor activation enhances norepinephrine release from nerves in the rabbit saphenous vein.
    The Journal of pharmacology and experimental therapeutics, 1999, Volume: 290, Issue:3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic alpha-Agonists; Adrenergic Fibers; Animals; Electric Stimulation; Ergolines; Male; Muscle Contraction; Norepinephrine; Oxadiazoles; Piperazines; Pyridines; Rabbits; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Saphenous Vein; Serotonin Antagonists; Serotonin Receptor Agonists; Sumatriptan; Synaptic Transmission

1999
Pharmacogenetic evidence for the involvement of 5-hydroxytryptamine (Serotonin)-1B receptors in the mediation of morphine antinociceptive sensitivity.
    The Journal of pharmacology and experimental therapeutics, 1999, Volume: 291, Issue:2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Analgesics; Animals; Dose-Response Relationship, Drug; Drug Interactions; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Morphine; Oxadiazoles; Piperazines; Receptors, Serotonin; Sensitivity and Specificity; Serotonin Antagonists; Species Specificity; Time Factors

1999
Lack of evidence for a role of serotonin in interleukin-1-induced hypophagia.
    Pharmacology, biochemistry, and behavior, 2000, Volume: 65, Issue:3

    Topics: 5,7-Dihydroxytryptamine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Eating; Interleukin-1; Ketanserin; Lipopolysaccharides; Male; Mice; Oxadiazoles; Piperazines; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Spiro Compounds; Sulfonamides

2000
Yohimbine produces antinociception in the formalin test in rats: involvement of serotonin(1A) receptors.
    Psychopharmacology, 2000, Volume: 149, Issue:1

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic alpha-Antagonists; Animals; Benzofurans; Bridged Bicyclo Compounds, Heterocyclic; Dose-Response Relationship, Drug; Ergolines; Formaldehyde; Male; Nociceptors; Oxadiazoles; Pain; Pain Measurement; Piperazines; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1D; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Antagonists; Serotonin Receptor Agonists; Time Factors; Yohimbine

2000
5-HT(1A) and 5-HT(1B/1D) receptors are involved in the modulation of the trigeminovascular system of the cat: a microiontophoretic study.
    Neuropharmacology, 2000, Jul-24, Volume: 39, Issue:10

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Action Potentials; Animals; Benzopyrans; Cats; Electric Stimulation; Iontophoresis; Oxadiazoles; Piperazines; Propylamines; Pyridines; Pyrimidines; Receptor, Serotonin, 5-HT1B; Receptor, Serotonin, 5-HT1D; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Antagonists; Trigeminal Caudal Nucleus

2000
Chronic clomipramine alters presynaptic 5-HT(1B) and postsynaptic 5-HT(1A) receptor sensitivity in rat hypothalamus and hippocampus, respectively.
    Neuropharmacology, 2000, Volume: 39, Issue:12

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antidepressive Agents, Tricyclic; Clomipramine; Corticosterone; Cyclic AMP; Hippocampus; Hypothalamus; Male; Microdialysis; Oxadiazoles; Piperazines; Rats; Receptor, Serotonin, 5-HT1B; Receptors, Presynaptic; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin; Serotonin Antagonists

2000
Chronic repetitive transcranial magnetic stimulation induces subsensitivity of presynaptic serotonergic autoreceptor activity in rat brain.
    Neuroreport, 2000, Sep-11, Volume: 11, Issue:13

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Autoreceptors; Depression; Male; Microdialysis; Oxadiazoles; Piperazines; Prefrontal Cortex; Presynaptic Terminals; Rats; Rats, Inbred Strains; Receptor, Serotonin, 5-HT1B; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin; Serotonin Antagonists; Transcranial Magnetic Stimulation

2000
Functional effects of corticosterone on 5-HT(1A) and 5-HT(1B) receptor activity in rat brain: in vivo microdialysis studies.
    European journal of pharmacology, 2001, Jan-05, Volume: 411, Issue:1-2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Anti-Inflammatory Agents; Brain; Colforsin; Corticosterone; Cyclic AMP; Hippocampus; Hypothalamus; Male; Microdialysis; Oxadiazoles; Piperazines; Rats; Receptor, Serotonin, 5-HT1B; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists

2001
Role of 5-HT(1A) and 5-HT(1B) receptors in the mediation of behavior in the forced swim test in mice.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2001, Volume: 24, Issue:4

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antidepressive Agents, Tricyclic; Behavior, Animal; Dose-Response Relationship, Drug; Female; Imipramine; Indoles; Mice; Mice, Inbred Strains; Motor Activity; Oxadiazoles; Piperazines; Piperidines; Pyridines; Reaction Time; Receptor, Serotonin, 5-HT1B; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Antagonists; Serotonin Receptor Agonists; Swimming

2001
No involvement of 5-HT(7) or 5-HT(1D) receptors in the (R)-8-OH-DPAT-induced depression of the monosynaptic reflex in spinalized rats.
    European journal of pharmacology, 2001, Sep-14, Volume: 427, Issue:2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Clozapine; Decerebrate State; Dose-Response Relationship, Drug; Ergolines; Indoles; Male; Methiothepin; Oxadiazoles; Phenols; Piperazines; Pyridines; Rats; Receptor, Serotonin, 5-HT1D; Receptors, Serotonin; Reflex, Monosynaptic; Serotonin Antagonists; Serotonin Receptor Agonists; Sulfonamides; Time Factors

2001
Effects of chronically administered venlafaxine on 5-HT receptor activity in rat hippocampus and hypothalamus.
    European journal of pharmacology, 2002, Feb-01, Volume: 436, Issue:1-2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Corticosterone; Cyclohexanols; Hippocampus; Hypothalamus; Male; Oxadiazoles; Oxytocin; Piperazines; Rats; Receptors, Serotonin; Selective Serotonin Reuptake Inhibitors; Serotonin Antagonists; Serotonin Receptor Agonists; Venlafaxine Hydrochloride

2002
Activation of 5-HT(1B) receptors in the nucleus accumbens reduces self-administration of amphetamine on a progressive ratio schedule.
    Pharmacology, biochemistry, and behavior, 2002, Volume: 71, Issue:4

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamine; Amphetamines; Animals; Central Nervous System Stimulants; Conditioning, Operant; Dose-Response Relationship, Drug; Food; Male; Nucleus Accumbens; Oxadiazoles; Piperazines; Pyridines; Pyrroles; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1B; Receptors, Serotonin; Reinforcement Schedule; Self Administration; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists

2002
Functional effects of chronic electroconvulsive shock on serotonergic 5-HT(1A) and 5-HT(1B) receptor activity in rat hippocampus and hypothalamus.
    Brain research, 2002, Oct-11, Volume: 952, Issue:1

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Cyclic AMP; Electroshock; Extracellular Space; Hippocampus; Hypothalamus; Male; Oxadiazoles; Piperazines; Rats; Rats, Inbred Strains; Receptor, Serotonin, 5-HT1B; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Synaptic Transmission

2002
The differential effects of food restriction on 5-HT1A and 5-HT1B receptor mediated control of serotonergic transmission in the hippocampus and hypothalamus of rats.
    Nutritional neuroscience, 2003, Volume: 6, Issue:3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Body Weight; Female; Hippocampus; Hypothalamus; Oxadiazoles; Piperazines; Rats; Receptor, Serotonin, 5-HT1B; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists

2003
Chronic reductions in serotonin transporter function prevent 5-HT1B-induced behavioral effects in mice.
    Biological psychiatry, 2009, Mar-01, Volume: 65, Issue:5

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Female; Fluoxetine; Globus Pallidus; Indoles; Mice; Mice, Inbred BALB C; Mice, Knockout; Motor Activity; Oxadiazoles; Piperazines; Pyridines; Receptor, Serotonin, 5-HT1B; Reflex, Startle; Serotonin 5-HT1 Receptor Agonists; Serotonin 5-HT1 Receptor Antagonists; Serotonin Plasma Membrane Transport Proteins; Substantia Nigra

2009
Differential involvement of 5-HT(1A) and 5-HT(1B/1D) receptors in human interferon-alpha-induced immobility in the mouse forced swimming test.
    Arzneimittel-Forschung, 2010, Volume: 60, Issue:3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Buspirone; Depression; Fluoxetine; Interferon-alpha; Male; Mice; Mice, Inbred ICR; Motor Activity; Oxadiazoles; Piperazines; Pyridines; Quinoxalines; Receptor, Serotonin, 5-HT1A; Receptor, Serotonin, 5-HT1B; Receptor, Serotonin, 5-HT1D; Selective Serotonin Reuptake Inhibitors; Serotonin 5-HT1 Receptor Agonists; Serotonin 5-HT1 Receptor Antagonists; Serotonin Antagonists; Serotonin Receptor Agonists; Swimming

2010
Lasting neurobehavioral abnormalities in rats after neonatal activation of serotonin 1A and 1B receptors: possible mechanisms for serotonin dysfunction in autistic spectrum disorders.
    Psychopharmacology, 2014, Volume: 231, Issue:6

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Animals, Newborn; Brain; Citalopram; Exploratory Behavior; Female; Freezing Reaction, Cataleptic; Locomotion; Male; Oxadiazoles; Piperazines; Pyridines; Quinoxalines; Rats; Rats, Long-Evans; Receptor, Serotonin, 5-HT1A; Receptor, Serotonin, 5-HT1B; Selective Serotonin Reuptake Inhibitors; Serotonin Antagonists; Serotonin Receptor Agonists; Social Behavior

2014
Serotonin antagonists fail to alter MDMA self-administration in rats.
    Pharmacology, biochemistry, and behavior, 2016, Volume: 148

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Drug-Seeking Behavior; Extinction, Psychological; Ketanserin; Male; N-Methyl-3,4-methylenedioxyamphetamine; Oxadiazoles; Piperazines; Pyridines; Rats; Rats, Sprague-Dawley; Self Administration; Serotonin Antagonists

2016