8-hydroxy-2-(di-n-propylamino)tetralin has been researched along with fluoxetine in 158 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (2.53) | 18.7374 |
| 1990's | 50 (31.65) | 18.2507 |
| 2000's | 66 (41.77) | 29.6817 |
| 2010's | 33 (20.89) | 24.3611 |
| 2020's | 5 (3.16) | 2.80 |
| Authors | Studies |
|---|---|
| Cortizo, L; García, N; Innerárity, A; Labeaga, L; Mosquera, R; Orjales, A; Pumar, MC; Toledo, A | 1 |
| Buck, LB; Petrascheck, M; Ye, X | 1 |
| Andree, TH; Baudy, R; Chlenov, M; Evrard, DA; Failli, A; Golembieski, J; Harrison, BL; Hatzenbuhler, NT; Hornby, G; Kagan, M; Lai, M; Lenicek, S; Mewshaw, RE; Saab, A; Schechter, LE; Shah, U; Smith, DL; Sullivan, KM; Sze, J; Zhang, M; Zhou, D | 1 |
| Aisa, B; Aldana, I; Battaglia, G; Berrade, L; Galiano, S; Guccione, S; Levy, FO; Molinaro, G; Moltzau, LR; Monge, A; Nicoletti, F; Perez-Silanes, S; Ramirez, MJ | 1 |
| Benedetti, G; Del Bello, F; Diamanti, E; Giannella, M; Mammoli, V; Marchioro, C; Mattioli, L; Piergentili, A; Pigini, M; Quaglia, W; Titomanlio, F; Varrone, M | 1 |
| Caselli, G; Del Bello, F; Diamanti, E; Giannella, M; Lanza, M; Mammoli, V; Mattioli, L; Piergentili, A; Pigini, M; Poggesi, E; Quaglia, W; Sabatini, C; Titomanlio, F | 1 |
| Cunningham, KA; Goeders, NE; Paris, JM | 1 |
| Chen, HY; Lee, EH; Liang, KC; Lin, WR; Shiu, WH | 1 |
| Dun, NJ; Wang, MY; Wu, SY | 1 |
| Neuman, RS; Thompson, PM; Zebrowski, G | 1 |
| Fone, KC; Marsden, CA; Robinson, AJ | 1 |
| Bridger, WH; Friedman, E; Yadin, E | 1 |
| Li, ET; Luo, SQ; Ransom, T | 1 |
| Brain, PF; Haug, M; Wallian, L | 1 |
| Ciesielski, L; Gobaille, S; Isel, F; Mandel, P; Molina, V | 1 |
| De Montigny, C; Desjardins, P; Desroches, J; Suranyi-Cadotte, BE; Welner, SA | 1 |
| Li, TK; Lumeng, L; McBride, WJ; Murphy, JM | 1 |
| Cooper, SJ; Neill, JC | 1 |
| Doucet, E; Hamon, M; Laaris, N; Lanfumey, L; Laporte, AM; Le Poul, E | 1 |
| Hong, E; Meneses, A | 1 |
| Kreiss, DS; Lucki, I | 1 |
| Auerbach, SB; Rutter, JJ | 1 |
| Hyttel, J; Sánchez, C | 1 |
| Peltier, R; Schenk, S | 1 |
| Kruk, ZL; O'Connor, JJ | 1 |
| Berendsen, HH; Broekkamp, CL | 2 |
| Han, JS; Qiu, XC; Xu, W | 1 |
| Auerbach, SB; Gundlah, C; Rutter, JJ | 1 |
| Chambers, JW; Coscina, DV; Currie, PJ; Fletcher, PJ | 1 |
| Battaglia, G; Brownfield, MS; Cabrera, TM; Levy, AD; Li, Q; Van de Kar, LD | 1 |
| Aguilar, E; Aguilar, R; Pinilla, L; Ranchal, A | 1 |
| Cheng, CH; Costall, B; Naylor, RJ; Rudd, JA | 1 |
| Cumming, P; Gjedde, A | 1 |
| Maj, J; Moryl, E | 1 |
| Hoebel, BG; Mark, GP; Rada, PV | 1 |
| Bramante, M; Invernizzi, R; Samanin, R | 1 |
| Gallagher, JP; Simms, D | 1 |
| Gale, K; Pasini, A; Tortorella, A | 1 |
| Afkhami-Dastjerdian, S; Carli, M; Reader, TA | 1 |
| Bores, GM; Corbett, R; Klein, JT; Kongsamut, S; Roehr, JE; Smith, CP; Szewczak, MR; Woods-Kettelberger, AT | 1 |
| Li, Q; Muma, NA; van de Kar, LD | 1 |
| Auerbach, SB; Gundlah, C; Heal, DJ; Martin, KF | 1 |
| Battaglia, G; Li, Q; Van de Kar, LD | 1 |
| Rowe, PM | 1 |
| Leander, JD; Wolff, MC | 2 |
| Coscina, DV; Currie, PJ; Fletcher, PJ | 1 |
| Gean, PW; Lu, KT | 1 |
| Ashby, CR; Katsumori, H; Minabe, Y; Watanabe, K | 1 |
| Anmella, MC; Gardier, AM; Jacquot, C; Langlois, M; Malagié, I; Mathe-Allainmat, M; Trillat, AC | 1 |
| Battaglia, G; Evans, S; Garcia, F; Li, Q; Muma, NA; Raap, DK; Van De Kar, LD; Wolf, WA | 1 |
| Battaglia, G; Garcia, F; Muma, NA; Raap, DK; van de Kar, LD; Wolf, WA | 1 |
| Braselton, J; Clarke, T; Reynolds, L; Rollema, H; Sprouse, J | 2 |
| File, SE; Gonzalez, LE; Ouagazzal, AM; Overstreet, DH | 1 |
| Aguerre, S; Berton, O; Chaouloff, F; Durand, M; Mormède, P | 1 |
| Moser, PC; Sanger, DJ | 1 |
| Chau, D; Hoebel, BG; Kosloff, RA; Rada, PV | 1 |
| Gobert, A; Millan, MJ | 1 |
| Cistarelli, L; Gobert, A; Melon, C; Millan, MJ; Rivet, JM | 1 |
| Cousins, MS; Overstreet, DH; Seiden, LS; Vosmer, G | 1 |
| Baschirotto, A; Borsini, F; Brambilla, A; Grippa, N | 1 |
| López-Rubalcava, C; Lucki, I | 1 |
| Jagadeesh, S; Srinivas, BN; Subhash, MN; Vinod, KY | 1 |
| Dawson, LA; Nguyen, HQ; Schechter, LE; Smith, DI | 1 |
| Battaglia, G; Garcia, F; Muma, NA; Raap, DK; Serres, F; Van de Kar, LD | 1 |
| Branchek, TA; Calligaro, DO; Czachura, JF; Dreshfield-Ahmad, LJ; Evans, DC; Hemrick-Luecke, SK; Kallman, MJ; Kendrick, WT; Leander, JD; Nelson, DL; Overshiner, CD; Rasmussen, K; Wainscott, DB; Wolff, MC; Wong, DT; Xu, YC; Zgombick, JM | 1 |
| Artigas, F; Hervás, I; Mengod, G; Romero, L; Scorza, MC; Vilaró, MT | 1 |
| Bouvard, M; Rénéric, JP; Stinus, L | 1 |
| Anheuer, ZE; Bagdy, G; Graf, M; Kantor, S | 1 |
| Harrison, AA; Markou, A | 1 |
| Arai, Y; Hishinuma, T; Hozumi, M; Kinemuchi, H; Kisara, K; Mizugaki, M; Nakagawasai, O; Niijima, F; Oka, R; Satoh, N; Tadano, T; Tan-no, K; Yasuhara, H | 1 |
| Borsini, F; Brambilla, A; Cesana, R; Grippa, N | 1 |
| Blendy, JA; Hen, R; Knobelman, DA; Lucki, I | 1 |
| Kaur, G; Kulkarni, SK | 1 |
| Fornal, CA; Jacobs, BL; Metzler, CW; Mirescu, C; Stein, SK | 1 |
| Costentin, J; El Yacoubi, M; Leroux-Nicollet, I; Naudon, L; Vaugeois, JM | 1 |
| Del Río, J; Lasheras, B; Monge, A; Tordera, RM | 1 |
| Dawson, LA; Nguyen, HQ; Schechter, LE; Smith, DL | 1 |
| Carbone, KM; Moran, TH; Pletnikov, MV; Rubin, SA; Vogel, MW | 1 |
| Cryan, JF; Dalvi, A; Lucki, I; Manning, DR; Page, ME; Saucy, B; Sullivan, A | 1 |
| Battaglia, G; DonCarlos, LL; Garcia, F; Muma, NA; Raap, DK; Van de Kar, LD | 1 |
| Overstreet, DH | 1 |
| Battaglia, G; D'Souza, DN; Garcia, F; Van De Kar, LD; Zhang, Y | 2 |
| Marsden, CA; Mason, R; Muchimapura, S | 1 |
| Sperry, TS; Thompson, CK; Wingfield, JC | 1 |
| Castro, M; del Olmo, E; Diaz, A; Pazos, A | 1 |
| Chapman, KE; Kelly, PA; Lai, M; McCormick, JA; Seckl, JR; Yau, JL | 1 |
| Arancio, O; Battaglia, F; Belzung, C; Dulawa, S; Duman, R; Gross, C; Hen, R; Lee, J; Santarelli, L; Saxe, M; Surget, A; Weisstaub, N | 1 |
| Fernández-Pérez, S; Pache, DM; Sewell, RD | 2 |
| Pan, WJ; Song, HR; Wang, F; Wang, YL; Wu, CF; Yang, JY | 1 |
| Braver, M; Currie, PJ; Mirza, A; Sricharoon, K | 1 |
| Adell, A; Amargós-Bosch, M; Artigas, F; Bortolozzi, A; Toth, M | 1 |
| Aihara, Y; Hasegawa, H; Ishiwata, T; Otokawa, M; Saito, T; Yazawa, T | 1 |
| Cavaillon, JM; Cloëz-Tayarani, I; Fanburg, BL; Kayyali, US | 1 |
| Bae, H; Cho, JH; Hong, M; Jang, CG; Kang, M; Kim, H; Lee, J; Lee, SB; Park, S; Park, SK; Shim, IS; Shin, MK | 1 |
| Gur, E; Lerer, B; Lifschytz, T; Newman, ME | 1 |
| Dalmus, M; De Vry, J; Jentzsch, KR; Melon, C; Schreiber, R | 1 |
| Araujo-Alvarez, JM; Delgado, A; Oviedo-Chávez, A; Querejeta, E; Quiñones-Cárdenas, AR | 1 |
| Bartoszyk, GD; Hagan, JJ; Kew, JN; Roberts, C | 1 |
| Balsara, JJ; Gaikwad, RV; Gaonkar, RK; Jadhav, JH; Jadhav, SA; Thorat, VM | 1 |
| de Bortoli, VC; Nogueira, RL; Zangrossi, H | 1 |
| Alici, T; Aygoren, MO; Kayir, H; Saglam, E; Uzbay, IT | 1 |
| Adrien, J; Barden, N; Evrard, A; Hamon, M | 1 |
| Orsingher, OA; Ramírez, OA; Sodero, AO | 1 |
| Agrati, D; Fernández-Guasti, A; Ferreira, A; Reyes, R | 1 |
| Lee, HM; Prosser, RA; Wehner, A | 1 |
| Nogueira, RL; Zangrossi, H; Zanoveli, JM | 1 |
| Aznavour, N; Descarries, L; Rbah, L; Riad, M; Verdurand, M; Zimmer, L | 1 |
| Challet, E; Clesse, D; Cuesta, M; Mendoza, J; Pévet, P | 1 |
| Borah, M; Radhakrishnan, M; Ramamoorthy, R | 1 |
| Adrien, J; Alexandre, C; Léna, C; Popa, D | 1 |
| Craighead, M; Gartside, SE; Grant, EJ; Ingram, CD; Johnson, DA | 1 |
| Hummel, R; Jacobsen, JP; Mirza, N; Nielsen, EØ; Redrobe, JP; Weikop, P | 1 |
| Castro, E; Del Olmo, E; Díaz, A; Pazos, A; Rodriguez-Gaztelumendi, A | 1 |
| Ansorge, M; Dulawa, SC; Geyer, MA; Gingrich, JA; Hen, R; Holick Pierz, KA; Masten, VL; Shanahan, NA; Waeber, C | 1 |
| Limebeer, CL; Litt, DE; Parker, LA | 1 |
| Glass, JD; Kaur, G; Thind, R | 1 |
| J M, V; N S, J; P V, D; S N, U | 1 |
| Arai, Y; Chancellor, MB; de Groat, WC; Kaiho, Y; Kamo, I; Kitta, T; Miyazato, M; Sugaya, K; Yoshimura, N | 1 |
| Hu, Y; Huang, XY; Luo, CX; Wu, DL; Wu, HY; Ye, ML; Zhang, J; Zhou, QG; Zhu, DY; Zhu, LJ | 1 |
| Guptarak, J; Hiegel, C; Sarkar, J; Uphouse, L | 1 |
| Crespi, F | 1 |
| Ermani, M; Freo, U; Merico, A; Ori, C | 1 |
| Jiang, Z; Shang, J; Wang, W; Zhang, H; Zhang, L | 1 |
| Akagawa, K; Fujiwara, T; Kofuji, T; Snada, M; Yoshikawa, T | 1 |
| Cheng, FC; Feng, JJ; Lin, CH; Wei, JW; Yang, SD | 1 |
| Maswood, N; Miryala, CS; Uphouse, L | 1 |
| Alvarado, G; Artigas, F; Bortolozzi, A; Carmona, MC; Castañé, A; Cortés, R; Fernández, G; Ferrés-Coy, A; Montefeltro, A; Perales, JC; Santana, N; Semakova, J; Toth, M | 1 |
| Jope, RS; Li, X; Polter, AM; Yang, S | 1 |
| Alvarez, E; Artigas, F; Celada, P; Cortés, R; Lladó-Pelfort, L; Oller, S; Pérez, V; Pérez-Egea, R; Portella, MJ; Puigdemont, D; Scorza, MC | 1 |
| Banas, SM; Belmer, A; Boutourlinsky, K; Diaz, SL; Doly, S; Fernández, S; Maroteaux, L; Mazot, P; Moutkine, I; Narboux-Nême, N; Roumier, A | 1 |
| Artigas, F; Bortolozzi, A; Carmona, MC; Castañé, A; Cortés, R; Ferrés-Coy, A; Montefeltro, A; Santana, N; Toth, M | 1 |
| Descarries, L; Riad, M | 1 |
| Li, Q; McAllister, CE; Muma, NA; Sullivan, NR; Van de Kar, LD | 1 |
| Chavira, R; Fernández-Guasti, A; Olvera-Hernández, S | 1 |
| Babapour, V; Baghbanzadeh, A; Hassanpour, S; Mokhtarpouriani, K; Pourrahimi, M; Zendehdel, M | 1 |
| Auregan, G; David, DJ; David, I; Déglon, N; Dranovsky, A; Gaillard, MC; Gardier, AM; Guiard, BP; Hantraye, P; Hen, R; Nguyen, HT; Nicolas, V; Pla, P; Quesseveur, G; Wu, MV | 1 |
| Arrant, AE; Coburn, E; Jacobsen, J; Kuhn, CM | 1 |
| Li, Q; Muma, NA | 1 |
| Aristieta, A; Arrue, A; Miguelez, C; Morera-Herreras, T; Ruiz-Ortega, JA; Ugedo, L; Vidaurrazaga, I; Zumarraga, M | 1 |
| Seyfried, CA; van Amsterdam, C | 1 |
| Bentham, MP; Blakeman, S; Einstein, EB; Mineur, YS; Newbold, SA; Picciotto, MR; Wigestrand, MB | 1 |
| Ceci, A; Doods, H; Hu, B; Treede, RD | 1 |
| Amigó, J; Castro, E; Compan, V; Díaz, A; Martín, A; Pazos, A; Pilar-Cuéllar, F; Vidal, R | 1 |
| Albers, HE; Hardcastle, N; Larkin, TE; Norvelle, A; Riaz, A; Song, Z; Terranova, JI | 1 |
| Antle, MC; Dyck, RH; Kiryanova, V; Smith, VM | 1 |
| Banas, SM; Belmer, A; Diaz, SL; Doly, S; Fernandez, SP; Guiard, BP; Mameli, M; Maroteaux, L; Moutkine, I; Muzerelle, A; Pitychoutis, PM; Quentin, E; Roumier, A; Tchenio, A | 1 |
| Bregman, T; Diwan, M; Fletcher, PJ; Hamani, C; Nobrega, JN; Raymond, R; Scott, B; Volle, J | 1 |
| Ahmadi, SA; Haddadi, R; Sabahi, M | 1 |
| de Boer, SF; de Waard, J; Houwing, DJ; Olivier, JDA; Ramsteijn, AS; Wams, EJ; Woelders, T | 1 |
| Mininni, CJ; Pereyra, AE; Zanutto, BS | 1 |
| Alatorre, A; Barrientos, R; Delgado, A; Nielsen, N; Oviedo-Chávez, A; Querejeta, E | 1 |
| Chen, R; Li, N; Shi, HJ; Wu, DL; Zhu, LJ | 1 |
| Becegato, M; Bioni, VS; Cunha, DMG; Kurita, JPF; Leão, AHFF; Lima, AC; Lopes-Silva, LB; Marinho, GF; Paiva-Santos, MA; Ribeiro, AM; Silva, RH; Wuo-Silva, R | 1 |
2 review(s) available for 8-hydroxy-2-(di-n-propylamino)tetralin and fluoxetine
| Article | Year |
|---|---|
Behavioral characteristics of rat lines selected for differential hypothermic responses to cholinergic or serotonergic agonists.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Behavior, Animal; Cholinergic Agonists; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Fluoxetine; Genetics, Behavioral; Hypothermia; Isoflurophate; Rats; Rats, Inbred Strains; Receptors, Cholinergic; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Selection, Genetic; Selective Serotonin Reuptake Inhibitors; Serotonin Receptor Agonists | 2002 |
Effects of the antidepressant fluoxetine on the subcellular localization of 5-HT1A receptors and SERT.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antidepressive Agents; Autoreceptors; Cats; Cell Membrane; Dendrites; Fluoxetine; Humans; Immunohistochemistry; Microscopy, Immunoelectron; Rats; Receptor, Serotonin, 5-HT1A; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Plasma Membrane Transport Proteins | 2012 |
1 trial(s) available for 8-hydroxy-2-(di-n-propylamino)tetralin and fluoxetine
| Article | Year |
|---|---|
Preclinical and clinical characterization of the selective 5-HT(1A) receptor antagonist DU-125530 for antidepressant treatment.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adult; Animals; Antidepressive Agents; Brain; Depressive Disorder, Major; Drug Therapy, Combination; Female; Fluoxetine; Humans; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Middle Aged; Piperazines; Pyridines; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT1A; Serotonin Antagonists; Serotonin Receptor Agonists; Thiazoles | 2012 |
155 other study(ies) available for 8-hydroxy-2-(di-n-propylamino)tetralin and fluoxetine
| Article | Year |
|---|---|
Syntheses and binding studies of new [(aryl)(aryloxy)methyl]piperidine derivatives and related compounds as potential antidepressant drugs with high affinity for serotonin (5-HT) and norepinephrine (NE) transporters.
Topics: Adrenergic Uptake Inhibitors; Animals; Antidepressive Agents; Brain; Carrier Proteins; Fluoxetine; In Vitro Techniques; Male; Membrane Glycoproteins; Membrane Transport Proteins; Morpholines; Nerve Tissue Proteins; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Piperidines; Radioligand Assay; Rats; Rats, Wistar; Reboxetine; Receptor, Serotonin, 5-HT1A; Receptor, Serotonin, 5-HT2A; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Plasma Membrane Transport Proteins; Stereoisomerism; Structure-Activity Relationship; Symporters | 2003 |
An antidepressant that extends lifespan in adult Caenorhabditis elegans.
Topics: Aging; Animals; Antidepressive Agents; Caenorhabditis elegans; Caloric Restriction; Humans; Longevity; Methiothepin; Mianserin; Octopamine; Receptors, Biogenic Amine; Receptors, Serotonin, 5-HT4; Serotonin; Serotonin 5-HT4 Receptor Antagonists; Serotonin Antagonists; Signal Transduction; Starvation | 2007 |
Advances toward new antidepressants with dual serotonin transporter and 5-HT1A receptor affinity within a class of 3-aminochroman derivatives. Part 2.
Topics: Animals; Antidepressive Agents; Benzopyrans; Cell Line; Cricetinae; Cross-Linking Reagents; Humans; Molecular Structure; Rats; Receptor, Serotonin, 5-HT1A; Selective Serotonin Reuptake Inhibitors; Serotonin 5-HT1 Receptor Antagonists; Serotonin Plasma Membrane Transport Proteins; Structure-Activity Relationship | 2008 |
Novel benzo[b]thiophene derivatives as new potential antidepressants with rapid onset of action.
Topics: Antidepressive Agents; Magnetic Resonance Spectroscopy; Spectrophotometry, Infrared; Thiophenes | 2011 |
Low Doses of Allyphenyline and Cyclomethyline, Effective against Morphine Dependence, Elicit an Antidepressant-like Effect.
Topics: | 2012 |
Exploring multitarget interactions to reduce opiate withdrawal syndrome and psychiatric comorbidity.
Topics: | 2013 |
Chronic cocaine enhances serotonin autoregulation and serotonin uptake binding.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Autoradiography; Behavior, Animal; Brain; Brain Chemistry; Cocaine; Electrophysiology; Fluoxetine; Male; Rats; Rats, Inbred Strains; Serotonin; Tetrahydronaphthalenes | 1992 |
Fluoxetine and 8-OH-DPAT in the lateral septum enhances and impairs retention of an inhibitory avoidance response in rats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Avoidance Learning; Brain Mapping; Dose-Response Relationship, Drug; Fear; Fluoxetine; Injections; Ketanserin; Male; Mental Recall; Rats; Rats, Inbred Strains; Receptors, Serotonin; Retention, Psychology; Ritanserin; Septum Pellucidum; Tetrahydronaphthalenes; Zimeldine | 1992 |
Serotonin via presynaptic 5-HT1 receptors attenuates synaptic transmission to immature rat motoneurons in vitro.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Dose-Response Relationship, Drug; Evoked Potentials; Fluoxetine; Glutamates; Glutamic Acid; In Vitro Techniques; Membrane Potentials; Motor Neurons; Piperazines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin; Spinal Nerve Roots; Synapses; Synaptic Transmission; Tetrahydronaphthalenes | 1991 |
Alteration of neocortical activity in response to noxious stimulation: participation of the dorsal raphe.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Baclofen; Cerebral Cortex; Cortical Synchronization; Epilepsy; Fluoxetine; Male; Physical Stimulation; Raphe Nuclei; Rats; Rats, Inbred Strains; Serotonin; Serotonin Antagonists; Tetrahydronaphthalenes | 1991 |
Characterization of the 5-HT receptor subtypes involved in the motor behaviours produced by intrathecal administration of 5-HT agonists in rats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Clorgyline; Fluoxetine; Injections, Spinal; Ketanserin; Male; Motor Activity; Muscle Contraction; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin; Tetrahydronaphthalenes | 1991 |
Spontaneous alternation behavior: an animal model for obsessive-compulsive disorder?
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Behavior, Animal; Disease Models, Animal; Fluoxetine; Learning; Male; Methoxydimethyltryptamines; Obsessive-Compulsive Disorder; Rats; Rats, Inbred Strains; Tetrahydronaphthalenes | 1991 |
Selective increase in carbohydrate intake by rats treated with 8-hydroxy-2-(di-n-propylamino)-tetraline or buspirone.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Analysis of Variance; Animals; Buspirone; Dietary Carbohydrates; Dose-Response Relationship, Drug; Drug Interactions; Eating; Fluoxetine; Food Preferences; Male; Naphthalenes; Rats; Rats, Inbred Strains; Tetrahydronaphthalenes | 1990 |
Effects of 8-OH-DPAT and fluoxetine on activity and attack by female mice towards lactating intruders.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aggression; Animals; Behavior, Animal; Brain Chemistry; Female; Fluoxetine; Lactation; Mice; Serotonin Antagonists; Tetrahydronaphthalenes | 1990 |
Inhibition of mouse killing behavior by serotonin-mimetic drugs: effects of partial alterations of serotonin neurotransmission.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aggression; Animals; Citalopram; Fenclonine; Fluoxetine; Hydroxyindoleacetic Acid; Male; Methoxydimethyltryptamines; Motor Activity; Propylamines; Raphe Nuclei; Rats; Rats, Inbred Strains; Serotonin; Tetrahydronaphthalenes | 1987 |
Autoradiographic quantification of serotonin1A receptors in rat brain following antidepressant drug treatment.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amitriptyline; Animals; Antidepressive Agents; Brain; Fluoxetine; Male; Rats; Receptors, Serotonin; Tetrahydronaphthalenes | 1989 |
Spiroxatrine augments fluoxetine-induced reduction of ethanol intake by the P line of rats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Alcohol Drinking; Animals; Dioxanes; Dioxins; Dopamine Antagonists; Female; Fluoxetine; Rats; Spiro Compounds; Tetrahydronaphthalenes | 1989 |
Evidence for serotonergic modulation of sucrose sham-feeding in the gastric-fistulated rat.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Brain; Eating; Fenfluramine; Fluoxetine; Male; Neurons; Quipazine; Rats; Rats, Inbred Strains; Satiation; Satiety Response; Serotonin; Stomach; Taste; Tetrahydronaphthalenes | 1988 |
Early desensitization of somato-dendritic 5-HT1A autoreceptors in rats treated with fluoxetine or paroxetine.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Autoradiography; Brain Stem; Electrophysiology; Fluoxetine; In Vitro Techniques; Male; Neurons; Paroxetine; Piperazines; Pyridines; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists | 1995 |
The activation of serotonergic 5-HT1A presynaptic receptors or an enhancement of 5-HT postsynaptic activity increase learning.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Conditioning, Operant; Fluoxetine; Learning; Male; Rats; Rats, Wistar; Receptors, Presynaptic; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Stimulation, Chemical; Synapses | 1995 |
Effects of acute and repeated administration of antidepressant drugs on extracellular levels of 5-hydroxytryptamine measured in vivo.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antidepressive Agents; Autoreceptors; Corpus Striatum; Fluoxetine; Hippocampus; Male; Mianserin; Rats; Rats, Sprague-Dawley; Serotonin | 1995 |
Acute uptake inhibition increases extracellular serotonin in the rat forebrain.
Topics: 1-Naphthylamine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Corpus Striatum; Diencephalon; Fenfluramine; Fluoxetine; Hydroxyindoleacetic Acid; Male; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Serotonin; Sertraline | 1993 |
Isolation-induced aggression in mice: effects of 5-hydroxytryptamine uptake inhibitors and involvement of postsynaptic 5-HT1A receptors.
Topics: 1-Naphthylamine; 5-Hydroxytryptophan; 8-Hydroxy-2-(di-n-propylamino)tetralin; Aggression; Analysis of Variance; Animals; Behavior, Animal; Brain; Citalopram; Dose-Response Relationship, Drug; Fenclonine; Fluoxetine; Fluvoxamine; Male; Mice; Paroxetine; Penbutolol; Piperidines; Rats; Rats, Wistar; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Selective Serotonin Reuptake Inhibitors; Sertraline; Synaptosomes | 1994 |
Effects of serotonergic manipulations on cocaine self-administration in rats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Cocaine; Dose-Response Relationship, Drug; Fluoxetine; Male; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Reinforcement Schedule; Self Administration; Serotonin; Serotonin Receptor Agonists | 1993 |
Effects of 21 days treatment with fluoxetine on stimulated endogenous 5-hydroxytryptamine overflow in the rat dorsal raphe and suprachiasmatic nucleus studied using fast cyclic voltammetry in vitro.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Behavior, Animal; Body Weight; Electric Stimulation; Electrophysiology; Fluoxetine; In Vitro Techniques; Indoles; Male; Methiothepin; Presynaptic Terminals; Raphe Nuclei; Rats; Rats, Wistar; Serotonin; Serotonin Receptor Agonists; Suprachiasmatic Nucleus | 1994 |
Comparison of stimulus properties of fluoxetine and 5-HT receptor agonists in a conditioned taste aversion procedure.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Analysis of Variance; Animals; Avoidance Learning; Conditioning, Classical; Fluoxetine; Male; Mice; Paroxetine; Pyrazines; Serotonin Receptor Agonists; Taste | 1994 |
Serotonin receptor subtypes in spinal antinociception in the rat.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Analgesia; Animals; Female; Fluoxetine; Indoles; Male; Rats; Rats, Wistar; Receptors, Serotonin; Reflex; Serotonin; Skin Temperature; Spinal Cord; Tropisetron | 1994 |
Increase in extracellular serotonin produced by uptake inhibitors is enhanced after chronic treatment with fluoxetine.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Diencephalon; Electrophysiology; Extracellular Space; Fluoxetine; Male; Microdialysis; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Serotonin | 1994 |
Radiofrequency lesions of the PVN fail to modify the effects of serotonergic drugs on food intake.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Body Weight; Clonidine; Feeding Behavior; Fenfluramine; Fluoxetine; Male; Paraventricular Hypothalamic Nucleus; Piperazines; Radio Waves; Rats; Rats, Sprague-Dawley | 1993 |
Long-term fluoxetine, but not desipramine, inhibits the ACTH and oxytocin responses to the 5-HT1A agonist, 8-OH-DPAT, in male rats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenocorticotropic Hormone; Animals; Cerebral Cortex; Desipramine; Fluoxetine; Hypothalamus; Male; Oxytocin; Rats; Rats, Sprague-Dawley; Receptors, Serotonin | 1993 |
Role of the serotonergic system in the control of gonadotropin secretion in prepubertal male rats.
Topics: 5-Hydroxytryptophan; 8-Hydroxy-2-(di-n-propylamino)tetralin; Analysis of Variance; Animals; Fenclonine; Fluoxetine; Follicle Stimulating Hormone; Luteinizing Hormone; Male; Orchiectomy; Pituitary Gland, Anterior; Rats; Rats, Wistar; Receptors, Serotonin; Serotonin; Sexual Maturation; Testosterone | 1994 |
The effect of 5-HT receptor ligands on the uptake of [3H]5-hydroxytryptamine into rat cortical synaptosomes.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Cerebral Cortex; Cocaine; Desipramine; Female; Fluoxetine; In Vitro Techniques; Indoles; Neurotransmitter Uptake Inhibitors; Paroxetine; Piperazines; Rats; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Synaptosomes; Tropisetron | 1993 |
Kinetics of the uptake of [3H]paroxetine in the rat brain.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antipyrine; Autoradiography; Blood Volume; Blood-Brain Barrier; Brain; Fluoxetine; Male; Paroxetine; Rats; Rats, Wistar; Receptors, Serotonin; Tomography, Emission-Computed | 1993 |
Effects of fluoxetine given chronically on the responsiveness of 5-HT receptor subpopulations to their agonists.
Topics: 5-Hydroxytryptophan; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Behavior, Animal; Body Temperature; Exploratory Behavior; Fenfluramine; Fluoxetine; Male; Mice; Motor Activity; Piperazines; Rats; Rats, Wistar; Receptors, Serotonin; Serotonin Receptor Agonists | 1993 |
In vivo modulation of acetylcholine in the nucleus accumbens of freely moving rats: I. Inhibition by serotonin.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Acetylcholine; Animals; Choline; Dose-Response Relationship, Drug; Fluoxetine; Infusions, Parenteral; Interneurons; Kinetics; Male; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Time Factors | 1993 |
Role of 5-HT1A receptors in the effects of acute chronic fluoxetine on extracellular serotonin in the frontal cortex.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Body Weight; Extracellular Space; Fluoxetine; Frontal Lobe; Male; Microdialysis; Piperazines; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists | 1996 |
Modification of serotonin responses in rat dorsolateral septal nucleus neurons by acute and chronic cocaine.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Behavior, Animal; Cocaine; Dose-Response Relationship, Drug; Fluoxetine; Male; Neurons; Rats; Rats, Sprague-Dawley; Septal Nuclei; Serotonin | 1996 |
The anticonvulsant action of fluoxetine in substantia nigra is dependent upon endogenous serotonin.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Anticonvulsants; Bicuculline; Convulsants; Fenclonine; Fluoxetine; gamma-Aminobutyric Acid; Male; Microinjections; Piperazines; Pyrimidines; Rats; Rats, Sprague-Dawley; Seizures; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Receptor Agonists; Substantia Nigra | 1996 |
[3H]8-OH-DPAT binding and serotonin content in rat cerebral cortex after acute fluoxetine, desipramine, or pargyline.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antidepressive Agents; Binding Sites; Cerebral Cortex; Desipramine; Dopamine; Fluoxetine; Gyrus Cinguli; Homovanillic Acid; Male; Monoamine Oxidase; Pargyline; Rats; Rats, Sprague-Dawley; Serotonin; Serotonin Receptor Agonists | 1996 |
Besipirdine (HP 749) reduces schedule-induced polydipsia in rats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Biogenic Amines; Blepharoptosis; Conditioning, Operant; Desipramine; Drinking Behavior; Female; Fluoxetine; Hippocampus; In Vitro Techniques; Indoles; Male; Mice; Neurotransmitter Uptake Inhibitors; Pyridines; Rats; Rats, Wistar; Receptors, Serotonin; Reinforcement Schedule; Selective Serotonin Reuptake Inhibitors; Serotonin Receptor Agonists; Sympatholytics; Synaptosomes | 1996 |
Chronic fluoxetine induces a gradual desensitization of 5-HT1A receptors: reductions in hypothalamic and midbrain Gi and G(o) proteins and in neuroendocrine responses to a 5-HT1A agonist.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenocorticotropic Hormone; Animals; Dose-Response Relationship, Drug; Fluoxetine; Frontal Lobe; GTP-Binding Proteins; Hypothalamus; Male; Mesencephalon; Oxytocin; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Selective Serotonin Reuptake Inhibitors; Serotonin Receptor Agonists | 1996 |
In vivo criteria to differentiate monoamine reuptake inhibitors from releasing agents: sibutramine is a reuptake inhibitor.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Cyclobutanes; Fenfluramine; Fluoxetine; Male; Microdialysis; Paroxetine; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Serotonin | 1997 |
Indirect in vivo 5-HT1A-agonistic effects of the new antidepressant mirtazapine.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Antidepressive Agents, Tricyclic; Behavior, Animal; Conditioning, Operant; Fluoxetine; Male; Mianserin; Mice; Mice, Inbred ICR; Mirtazapine; Pyrazines; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Selective Serotonin Reuptake Inhibitors; Serotonin Receptor Agonists; Taste | 1997 |
Autoradiographic evidence for differential G-protein coupling of 5-HT1A receptors in rat brain: lack of effect of repeated injections of fluoxetine.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Autoradiography; Brain; Fluoxetine; GTP-Binding Proteins; Guanylyl Imidodiphosphate; Hypothalamus; Injections; Male; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Selective Serotonin Reuptake Inhibitors; Serotonin Receptor Agonists; Time Factors; Tissue Distribution | 1997 |
How do antidepressants work?
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antidepressive Agents; Brain; Desipramine; Fluoxetine; Humans; Mianserin; Rats; Selective Serotonin Reuptake Inhibitors; Serotonin | 1995 |
Selective serotonin reuptake inhibitors potentiate 8-OH-DPAT-induced stimulus control in the pigeon.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Citalopram; Columbidae; Conditioning, Operant; Discrimination, Psychological; Drug Synergism; Fluoxetine; Generalization, Stimulus; Imipramine; Male; Neurotransmitter Uptake Inhibitors; Selective Serotonin Reuptake Inhibitors; Serotonin Receptor Agonists | 1998 |
Reversal of fenfluramine and fluoxetine anorexia by 8-OH-DPAT is attenuated following raphe injection of 5,7-dihydroxytryptamine.
Topics: 5,7-Dihydroxytryptamine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Anorexia; Brain; Corpus Striatum; Dopamine; Feeding Behavior; Fenfluramine; Fluoxetine; Hippocampus; Hydroxyindoleacetic Acid; Hypothalamus; Infusions, Parenteral; Male; Neurotoxins; Norepinephrine; Piperazines; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Serotonin; Serotonin Receptor Agonists | 1998 |
Endogenous serotonin inhibits epileptiform activity in rat hippocampal CA1 neurons via 5-hydroxytryptamine1A receptor activation.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Barium; Epilepsy; Excitatory Postsynaptic Potentials; Fluoxetine; Hippocampus; In Vitro Techniques; Ketanserin; Male; Membrane Potentials; Metergoline; Neurons; Oxadiazoles; Picrotoxin; Piperazines; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Synaptic Transmission; Tryptamines | 1998 |
Effect of acute administration of various 5-HT receptor agonists on focal hippocampal seizures in freely moving rats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Behavior, Animal; Electric Stimulation; Electrodes, Implanted; Electroencephalography; Epilepsy, Complex Partial; Fluoxetine; Hippocampus; Kindling, Neurologic; Male; Piperidines; Rats; Rats, Wistar; Selective Serotonin Reuptake Inhibitors; Serotonin Receptor Agonists | 1998 |
Synergistic neurochemical and behavioral effects of fluoxetine and 5-HT1A receptor antagonists.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Analysis of Variance; Animals; Chromatography, High Pressure Liquid; Drug Synergism; Eating; Fluoxetine; Hippocampus; Male; Microdialysis; Piperazines; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Antagonists | 1998 |
Daily injections of fluoxetine induce dose-dependent desensitization of hypothalamic 5-HT1A receptors: reductions in neuroendocrine responses to 8-OH-DPAT and in levels of Gz and Gi proteins.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Body Weight; Cytosol; Dose-Response Relationship, Drug; Drug Administration Schedule; Fluoxetine; GTP-Binding Proteins; Hormones; Hypothalamus; Male; Membrane Proteins; Neurosecretory Systems; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Selective Serotonin Reuptake Inhibitors; Serotonin Receptor Agonists | 1999 |
Sustained desensitization of hypothalamic 5-Hydroxytryptamine1A receptors after discontinuation of fluoxetine: inhibited neuroendocrine responses to 8-hydroxy-2-(Dipropylamino)Tetralin in the absence of changes in Gi/o/z proteins.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenocorticotropic Hormone; Animals; Brain; Drug Interactions; Fluoxetine; GTP-Binding Protein alpha Subunits, Gi-Go; Hypothalamus; Male; Oxytocin; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Selective Serotonin Reuptake Inhibitors; Sensitivity and Specificity; Serotonin Receptor Agonists; Substance Withdrawal Syndrome | 1999 |
Consequences of 5-HT re-uptake blockade on postsynaptic 5-HT1A receptor activation: an electrophysiological and neurochemical study in guinea pig dorsal raphe and hippocampus.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Electrophysiology; Fluoxetine; Guinea Pigs; Hippocampus; Raphe Nuclei; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Receptor Agonists; Synapses; Synaptic Transmission | 1998 |
Chronic fluoxetine in tests of anxiety in rat lines selectively bred for differential 5-HT1A receptor function.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antidepressive Agents, Second-Generation; Anxiety; Depression; Fluoxetine; Hippocampus; Interpersonal Relations; Microinjections; Motor Activity; Rats; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Receptor Agonists; Stereotaxic Techniques; Swimming | 1999 |
Behavioral, neuroendocrine and serotonergic consequences of single social defeat and repeated fluoxetine pretreatment in the Lewis rat strain.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Behavior, Animal; Brain; Corticosterone; Dominance-Subordination; Fluoxetine; Hypothalamo-Hypophyseal System; Male; Neurosecretory Systems; Pituitary-Adrenal System; Rats; Rats, Inbred Lew; Renin; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Receptor Agonists; Stress, Psychological; Tryptophan | 1999 |
5-HT1A receptor antagonists neither potentiate nor inhibit the effects of fluoxetine and befloxatone in the forced swim test in rats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Analysis of Variance; Animals; Antidepressive Agents; Antidepressive Agents, Second-Generation; Drug Interactions; Fluoxetine; Male; Monoamine Oxidase Inhibitors; Oxazoles; Pindolol; Piperazines; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Selective Serotonin Reuptake Inhibitors; Serotonin Antagonists; Swimming | 1999 |
Cholinergic, M1 receptors in the nucleus accumbens mediate behavioral depression. A possible downstream target for fluoxetine.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Acetylcholine; Animals; Arecoline; Depression; Female; Fluoxetine; Microinjections; Motor Activity; Nucleus Accumbens; Pirenzepine; Posture; Rats; Rats, Sprague-Dawley; Receptor, Muscarinic M1; Receptors, Muscarinic; Scopolamine; Swimming | 1999 |
Modulation of dialysate levels of dopamine, noradrenaline, and serotonin (5-HT) in the frontal cortex of freely-moving rats by (-)-pindolol alone and in association with 5-HT reuptake inhibitors: comparative roles of beta-adrenergic, 5-HT1A, and 5-HT1B re
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Betaxolol; Dopamine; Fluoxetine; Frontal Lobe; Guinea Pigs; Humans; Male; Microdialysis; Norepinephrine; Pindolol; Piperazines; Propanolamines; Pyridines; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT1B; Receptors, Adrenergic, beta; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists | 1999 |
Buspirone modulates basal and fluoxetine-stimulated dialysate levels of dopamine, noradrenaline and serotonin in the frontal cortex of freely moving rats: activation of serotonin1A receptors and blockade of alpha2-adrenergic receptors underlie its actions
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Brain Chemistry; Buspirone; Chromatography, High Pressure Liquid; Dopamine; Dopamine Antagonists; Drug Interactions; Fluoxetine; Frontal Lobe; Locomotion; Male; Microdialysis; Neural Inhibition; Norepinephrine; Oxazoles; Piperazines; Pyridines; Raclopride; Rats; Rats, Wistar; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists | 1999 |
Rats selectively bred for responsiveness to 5-hydroxytryptamine(1A) receptor stimulation: differences in differential reinforcement of low rate 72-second performance and response to serotonergic drugs.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic Uptake Inhibitors; Age Factors; Animals; Behavior, Animal; Biogenic Monoamines; Brain Chemistry; Conditioning, Operant; Desipramine; Dose-Response Relationship, Drug; Drug Interactions; Fluoxetine; Hypothermia; Ketanserin; Male; Rats; Receptors, Serotonin; Reinforcement Schedule; Selective Serotonin Reuptake Inhibitors; Serotonin Antagonists; Serotonin Receptor Agonists; Time Factors | 2000 |
Effect of flibanserin (BIMT 17), fluoxetine, 8-OH-DPAT and buspirone on serotonin synthesis in rat brain.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Benzimidazoles; Brain; Buspirone; Dose-Response Relationship, Drug; Fluoxetine; Male; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists | 1999 |
Strain differences in the behavioral effects of antidepressant drugs in the rat forced swimming test.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Analysis of Variance; Animals; Antidepressive Agents; Desipramine; Fluoxetine; Male; Motor Activity; Rats; Rats, Inbred WKY; Rats, Sprague-Dawley; Restraint, Physical; Species Specificity; Stress, Psychological; Swimming | 2000 |
Modulation of 5-HT1A receptor mediated response by fluoxetine in rat brain.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adenylyl Cyclases; Animals; Brain Chemistry; Fluoxetine; Male; Neurons; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Second Messenger Systems; Selective Serotonin Reuptake Inhibitors; Serotonin Receptor Agonists; Tritium | 2000 |
Effects of chronic fluoxetine treatment in the presence and absence of (+/-)pindolol: a microdialysis study.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Dose-Response Relationship, Drug; Fluoxetine; Frontal Lobe; Male; Microdialysis; Pindolol; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Time Factors | 2000 |
Coadministration of 5-hydroxytryptamine(1A) antagonist WAY-100635 prevents fluoxetine-induced desensitization of postsynaptic 5-hydroxytryptamine(1A) receptors in hypothalamus.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenocorticotropic Hormone; Animals; Fluoxetine; GTP-Binding Protein alpha Subunits, Gi-Go; Hypothalamus; Male; Oxytocin; Piperazines; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Antagonists | 2000 |
The novel 5-Hydroxytryptamine(1A) antagonist LY426965: effects on nicotine withdrawal and interactions with fluoxetine.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Acoustic Stimulation; Animals; Body Temperature; Columbidae; Corticosterone; Depression; Discrimination Learning; Drug Interactions; Fluoxetine; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Lip; Male; Microdialysis; Neurons; Nicotine; Piperidines; Posture; Rats; Rats, Long-Evans; Rats, Sprague-Dawley; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Reflex, Startle; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Smoking Cessation; Substance Withdrawal Syndrome; Sulfur Radioisotopes | 2000 |
Desensitization of 5-HT(1A) autoreceptors by a low chronic fluoxetine dose effect of the concurrent administration of WAY-100635.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Brain; Depressive Disorder; Fluoxetine; Male; Neurons; Piperazines; Pyridines; Radioligand Assay; Rats; Rats, Wistar; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin; Serotonin Antagonists | 2001 |
Idazoxan and 8-OH-DPAT modify the behavioral effects induced by either NA, or 5-HT, or dual NA/5-HT reuptake inhibition in the rat forced swimming test.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic alpha-Antagonists; Adrenergic Uptake Inhibitors; Animals; Behavior, Animal; Cyclopropanes; Desipramine; Dose-Response Relationship, Drug; Drug Interactions; Fluoxetine; Idazoxan; Male; Milnacipran; Motor Activity; Rats; Selective Serotonin Reuptake Inhibitors; Serotonin Receptor Agonists | 2001 |
Rapid desensitization of 5-HT(1A) receptors in Fawn-Hooded rats after chronic fluoxetine treatment.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Anxiety Disorders; Body Temperature; Depressive Disorder; Disease Models, Animal; Fluoxetine; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Selective Serotonin Reuptake Inhibitors; Serotonin Receptor Agonists | 2001 |
Serotonergic manipulations both potentiate and reduce brain stimulation reward in rats: involvement of serotonin-1A receptors.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aminopyridines; Animals; Brain; Dose-Response Relationship, Drug; Fluoxetine; Male; Piperazines; Raphe Nuclei; Rats; Rats, Wistar; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Reward; Serotonin Antagonists; Serotonin Receptor Agonists | 2001 |
Central serotonergic mechanisms on head twitch response induced by benzodiazepine receptor agonists.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Anti-Anxiety Agents; Azabicyclo Compounds; Behavior, Animal; Dihydroxytryptamines; Estazolam; Fluoxetine; GABA-A Receptor Agonists; Hypnotics and Sedatives; Ketanserin; Male; Mice; Piperazines; Receptors, GABA-A; Receptors, Serotonin; Selective Serotonin Reuptake Inhibitors; Serotonin Antagonists; Serotonin Receptor Agonists; Triazolam | 2001 |
Lack of interaction between flibanserin and antidepressants in inducing serotonergic syndrome in rats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antidepressive Agents; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Benzimidazoles; Drug Interactions; Fluoxetine; Imipramine; Male; Paroxetine; Rats; Rats, Sprague-Dawley; Serotonin Receptor Agonists; Serotonin Syndrome | 2001 |
Activation of postsynaptic 5-HT(1A) receptors by fluoxetine despite the loss of firing-dependent serotonergic input: electrophysiological and neurochemical studies.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Dose-Response Relationship, Drug; Excitatory Postsynaptic Potentials; Fluoxetine; Guinea Pigs; Hippocampus; Male; Neurons; Raphe Nuclei; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Receptor Agonists; Synaptic Transmission | 2001 |
Regional patterns of compensation following genetic deletion of either 5-hydroxytryptamine(1A) or 5-hydroxytryptamine(1B) receptor in the mouse.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Area Under Curve; Fluoxetine; Gene Deletion; Genotype; Male; Mice; Mice, Knockout; Microdialysis; Piperazines; Pyridines; Receptor, Serotonin, 5-HT1B; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Reverse Transcriptase Polymerase Chain Reaction; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists | 2001 |
Investigations on possible serotonergic involvement in effects of OB-200G (polyherbal preparation) on food intake in female mice.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Disease Models, Animal; Energy Intake; Feeding Behavior; Female; Fluoxetine; Hyperphagia; Mice; Plant Extracts; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Antagonists | 2001 |
Effects of standardized extracts of St. John's wort on the single-unit activity of serotonergic dorsal Raphe neurons in awake cats: comparisons with fluoxetine and sertraline.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Cats; Electrophysiology; Fluoxetine; Hypericum; Male; Membrane Potentials; Neurons; Piperazines; Plant Extracts; Pyridines; Raphe Nuclei; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Sertraline | 2001 |
A chronic treatment with fluoxetine decreases 5-HT(1A) receptors labeling in mice selected as a genetic model of helplessness.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Binding, Competitive; Brain; Depression; Disease Models, Animal; Down-Regulation; Drug Administration Schedule; Female; Fluoxetine; Helplessness, Learned; Mice; Mice, Inbred Strains; Motor Activity; Mutation; Neurons; Radioligand Assay; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Receptor Agonists; Synaptic Transmission; Tritium | 2002 |
Antidepressant-like activity of VN2222, a serotonin reuptake inhibitor with high affinity at 5-HT1A receptors.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antidepressive Agents; Avoidance Learning; Behavior, Animal; Binding, Competitive; Cells, Cultured; Cerebral Cortex; Cyclic AMP; Darkness; Dose-Response Relationship, Drug; Exploratory Behavior; Fluoxetine; HeLa Cells; Humans; Light; Male; Mesencephalon; Mice; Microdialysis; Motor Activity; Norepinephrine; Piperazines; Propanols; Rats; Rats, Wistar; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Receptor Agonists; Synaptosomes; Temperature; Transfection; Tritium | 2002 |
Effect of chronic fluoxetine and WAY-100635 treatment on serotonergic neurotransmission in the frontal cortex.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antidepressive Agents, Second-Generation; Extracellular Space; Fluoxetine; Male; Microdialysis; Piperazines; Prefrontal Cortex; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Synaptic Transmission | 2002 |
Effects of genetic background on neonatal Borna disease virus infection-induced neurodevelopmental damage. II. Neurochemical alterations and responses to pharmacological treatments.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animal Diseases; Animals; Animals, Newborn; Borna Disease; Brain; Brain Chemistry; Carrier Proteins; Dopamine; Dopamine Plasma Membrane Transport Proteins; Female; Fenclonine; Fluoxetine; Genetic Predisposition to Disease; Haloperidol; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Neurons; Neurotransmitter Agents; Norepinephrine; Pregnancy; Rats; Rats, Inbred F344; Rats, Inbred Lew; Receptor, Serotonin, 5-HT2A; Receptors, Dopamine D2; Receptors, Neurotransmitter; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin; Serotonin Plasma Membrane Transport Proteins | 2002 |
Behavioral and neurochemical effects of 5-(4-[4-(5-Cyano-3-indolyl)-butyl)-butyl]-1-piperazinyl)-benzofuran-2-carboxamide (EMD 68843): a combined selective inhibitor of serotonin reuptake and 5-hydroxytryptamine(1A) receptor partial agonist.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antidepressive Agents, Second-Generation; Behavior, Animal; Benzofurans; Brain Chemistry; Cell Line; Extracellular Space; Female; Fluoxetine; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Indoles; Microdialysis; Piperazines; Prefrontal Cortex; Protein Binding; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Selective Serotonin Reuptake Inhibitors; Serotonin Receptor Agonists; Swimming; Vilazodone Hydrochloride | 2002 |
Treatment of cycling female rats with fluoxetine induces desensitization of hypothalamic 5-HT(1A) receptors with no change in 5-HT(2A) receptors.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Analysis of Variance; Animals; Antidepressive Agents, Second-Generation; Body Weight; Corticosterone; DOM 2,5-Dimethoxy-4-Methylamphetamine; Drug Interactions; Estrous Cycle; Female; Fluoxetine; Hypothalamus; Pituitary Hormones; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Receptor Agonists | 2002 |
Selective serotonin reuptake inhibitors decrease impulsive behavior as measured by an adjusting delay procedure in the pigeon.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Alprazolam; Analysis of Variance; Animals; Anti-Anxiety Agents; Chlordiazepoxide; Columbidae; Cyclohexanes; Dose-Response Relationship, Drug; Fluoxetine; Impulsive Behavior; Male; Piperazines; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Reinforcement Schedule; Reward; Selective Serotonin Reuptake Inhibitors; Serotonin Receptor Agonists; Time Factors | 2002 |
Destruction of serotonergic nerve terminals prevents fluoxetine-induced desensitization of hypothalamic 5-HT(1A) receptors.
Topics: 5,7-Dihydroxytryptamine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenocorticotropic Hormone; Animals; Body Weight; Cerebral Cortex; Corticosterone; Dose-Response Relationship, Drug; Fluoxetine; Hypothalamus; Injections, Intraventricular; Male; Oxytocin; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Selective Serotonin Reuptake Inhibitors; Serotonin | 2002 |
Effect of isolation rearing on pre- and post-synaptic serotonergic function in the rat dorsal hippocampus.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Carbachol; Cholinergic Agonists; Fluoxetine; Hippocampus; In Vitro Techniques; Male; Motor Activity; Neurons; Paroxetine; Presynaptic Terminals; Rats; Rats, Inbred Strains; Receptor, Serotonin, 5-HT1B; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Social Isolation; Synapses | 2003 |
Effects of acute treatment with 8-OH-DPAT and fluoxetine on aggressive behaviour in male song sparrows (Melospiza melodia morphna).
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aggression; Animals; Behavior, Animal; Fluoxetine; Male; Selective Serotonin Reuptake Inhibitors; Serotonin Receptor Agonists; Songbirds | 2003 |
Chronic fluoxetine induces opposite changes in G protein coupling at pre and postsynaptic 5-HT1A receptors in rat brain.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Autoradiography; Autoreceptors; Brain; Fluoxetine; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); In Vitro Techniques; Male; Organ Specificity; Radioligand Assay; Rats; Rats, Wistar; Receptors, Presynaptic; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Selective Serotonin Reuptake Inhibitors; Serotonin Receptor Agonists; Synapses | 2003 |
Differential regulation of corticosteroid receptors by monoamine neurotransmitters and antidepressant drugs in primary hippocampal culture.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic beta-Antagonists; Amitriptyline; Animals; Animals, Newborn; Antidepressive Agents; Biogenic Monoamines; Blotting, Western; Carrier Proteins; Culture Techniques; DNA Primers; DNA, Complementary; Drug Interactions; Female; Fluoxetine; Gene Expression Regulation; Hippocampus; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Phenols; Piperazines; Pregnancy; Propranolol; Pyridines; Rats; Rats, Wistar; Receptors, Adrenergic; Receptors, Serotonin; Receptors, Steroid; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Selective Serotonin Reuptake Inhibitors; Serotonin Plasma Membrane Transport Proteins; Serotonin Receptor Agonists; Sulfonamides | 2003 |
Requirement of hippocampal neurogenesis for the behavioral effects of antidepressants.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antidepressive Agents; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Behavior, Animal; Cell Division; Conditioning, Psychological; Dentate Gyrus; Fear; Feeding Behavior; Fluoxetine; Grooming; Hippocampus; Long-Term Potentiation; Male; Mice; Mice, Knockout; Neurons; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Stress, Physiological; Synaptic Transmission | 2003 |
Buspirone differentially modifies short-term memory function in a combined delayed matching/non-matching to position task.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Behavior, Animal; Buspirone; Conditioning, Operant; Cues; Discrimination Learning; Drug Administration Schedule; Fluoxetine; Injections, Intraperitoneal; Injections, Subcutaneous; Male; Memory, Short-Term; Rats; Reaction Time; Receptor, Serotonin, 5-HT1A | 2003 |
Fluoxetine-induced changes in body weight and 5-HT1A receptor-mediated hormone secretion in rats on a tryptophan-deficient diet.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenocorticotropic Hormone; Animals; Body Weight; Brain; Corticosterone; Diet; Fluoxetine; Hormones; Male; Neurosecretory Systems; Oxytocin; Rats; Rats, Sprague-Dawley; Receptors, Serotonin, 5-HT1; Selective Serotonin Reuptake Inhibitors; Serotonin 5-HT1 Receptor Agonists; Serotonin Receptor Agonists; Tryptophan | 2004 |
The serotonergic system may be involved in the sleep-inducing action of oleamide in rats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Buspirone; Fenfluramine; Fluoxetine; Hypnotics and Sedatives; Male; Neural Pathways; Oleic Acids; Piperazines; Pyridines; Rats; Rats, Wistar; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Sleep; Sleep, REM; Wakefulness | 2003 |
Sex differences in the reversal of fluoxetine-induced anorexia following raphe injections of 8-OH-DPAT.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Anorexia; Dose-Response Relationship, Drug; Feeding Behavior; Female; Fluoxetine; Male; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1A; Selective Serotonin Reuptake Inhibitors; Serotonin 5-HT1 Receptor Agonists; Sex Factors | 2004 |
In vivo efflux of serotonin in the dorsal raphe nucleus of 5-HT1A receptor knockout mice.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Dose-Response Relationship, Drug; Extracellular Fluid; Fluoxetine; Handling, Psychological; Male; Mice; Mice, Knockout; Microdialysis; Pyridines; Pyrroles; Raphe Nuclei; Receptor, Serotonin, 5-HT1A; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin 5-HT1 Receptor Agonists; Serotonin Receptor Agonists; Sodium Chloride; Stress, Physiological | 2004 |
Changes of body temperature and extracellular serotonin level in the preoptic area and anterior hypothalamus after thermal or serotonergic pharmacological stimulation of freely moving rats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Anterior Hypothalamic Nucleus; Body Temperature; Cold Temperature; Fluoxetine; Hot Temperature; Hydroxyindoleacetic Acid; Male; Microdialysis; Preoptic Area; Rats; Rats, Wistar; Serotonin | 2004 |
5-HT activates ERK MAP kinase in cultured-human peripheral blood mononuclear cells via 5-HT1A receptors.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Cells, Cultured; Dose-Response Relationship, Drug; Extracellular Signal-Regulated MAP Kinases; Fluoxetine; Humans; Immunologic Factors; Ketanserin; Leukocytes, Mononuclear; Piperazines; Pyridines; Receptor, Serotonin, 5-HT1A; Serotonin; Serotonin 5-HT1 Receptor Agonists | 2004 |
Nelumbinis Semen reverses a decrease in 5-HT1A receptor binding induced by chronic mild stress, a depression-like symptom.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antidepressive Agents; Autoradiography; Depression; Fluoxetine; Hippocampus; Hypericum; Hypothalamus; Male; Plant Extracts; Plants, Medicinal; Prefrontal Cortex; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT1A; Serotonin Receptor Agonists; Stress, Psychological; Sucrose | 2004 |
Effects of triiodothyronine and fluoxetine on 5-HT1A and 5-HT1B autoreceptor activity in rat brain: regional differences.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Autoreceptors; Brain; Brain Chemistry; Depressive Disorder; Down-Regulation; Drug Synergism; Drug Therapy, Combination; Fluoxetine; Hypothalamus; Male; Microdialysis; Neurochemistry; Prefrontal Cortex; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT1A; Receptor, Serotonin, 5-HT1B; Selective Serotonin Reuptake Inhibitors; Serotonin; Triiodothyronine | 2004 |
5-HT1A receptors are differentially involved in the anxiolytic- and antidepressant-like effects of 8-OH-DPAT and fluoxetine in the rat.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Anti-Anxiety Agents; Antidepressive Agents; Antidepressive Agents, Second-Generation; Anxiety; Behavior, Animal; Dose-Response Relationship, Drug; Fenclonine; Fluoxetine; Male; Piperazines; Pyridines; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT1A; Receptors, Presynaptic; Selective Serotonin Reuptake Inhibitors; Serotonin Antagonists; Serotonin Receptor Agonists; Swimming; Vocalization, Animal | 2004 |
In vivo effects of local activation and blockade of 5-HT1B receptors on globus pallidus neuronal spiking.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Action Potentials; Anesthesia; Animals; Behavior, Animal; Denervation; Fluoxetine; Globus Pallidus; Male; Methiothepin; Neurons; Oxadiazoles; Piperazines; Pyridines; Quinolinic Acid; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT1B; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin 5-HT1 Receptor Antagonists; Serotonin Antagonists; Serotonin Receptor Agonists; Tryptamines | 2005 |
Effect of vilazodone on 5-HT efflux and re-uptake in the guinea-pig dorsal raphe nucleus.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Benzofurans; Dose-Response Relationship, Drug; Fluoxetine; Guinea Pigs; In Vitro Techniques; Indoles; Male; Piperazines; Pyridines; Raphe Nuclei; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Vilazodone Hydrochloride | 2005 |
Involvement of central serotonergic systems in dextromethorphan-induced behavioural syndrome in rats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antitussive Agents; Behavior, Animal; Buspirone; Central Nervous System; Dexfenfluramine; Dextromethorphan; Fluoxetine; Male; Propranolol; Rats; Rats, Wistar; Serotonin; Serotonin Receptor Agonists; Syndrome | 2005 |
Co-administration of fluoxetine and WAY100635 improves short-term memory function.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Analysis of Variance; Animals; Antidepressive Agents, Second-Generation; Buspirone; Drug Interactions; Fluoxetine; Male; Memory, Short-Term; Piperazines; Pyridines; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT1A; Serotonin 5-HT1 Receptor Agonists; Serotonin 5-HT1 Receptor Antagonists; Serotonin Antagonists; Serotonin Receptor Agonists | 2005 |
Effects of fluoxetine and buspirone on the panicolytic-like response induced by the activation of 5-HT1A and 5-HT2A receptors in the rat dorsal periaqueductal gray.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Anti-Anxiety Agents; Buspirone; Fluoxetine; Male; Microinjections; Periaqueductal Gray; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT1A; Receptor, Serotonin, 5-HT2A; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Receptor Agonists | 2006 |
Discriminative stimulus properties of tianeptine.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic Uptake Inhibitors; Animals; Antidepressive Agents; Caffeine; Central Nervous System Stimulants; Conditioning, Operant; Cyclohexanols; Discrimination Learning; Discrimination, Psychological; Fluoxetine; Male; Rats; Rats, Wistar; Selective Serotonin Reuptake Inhibitors; Serotonin Receptor Agonists; Thiazepines; Venlafaxine Hydrochloride | 2006 |
Glucocorticoid receptor-dependent desensitization of 5-HT1A autoreceptors by sleep deprivation: studies in GR-i transgenic mice.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Analysis of Variance; Animals; Autoreceptors; Dose-Response Relationship, Drug; Fluoxetine; Humans; Injections, Intraperitoneal; Mice; Mice, Transgenic; Neurons; Receptor, Serotonin, 5-HT1A; Selective Serotonin Reuptake Inhibitors; Serotonin Receptor Agonists; Sleep Deprivation | 2006 |
Altered serotonergic function of dorsal raphe nucleus in perinatally protein-deprived rats: effects of fluoxetine administration.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Action Potentials; Animals; Dose-Response Relationship, Drug; Female; Fluoxetine; Neurons; Pregnancy; Protein Deficiency; Raphe Nuclei; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT1A; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Receptor Agonists | 2006 |
Ovarian steroids counteract serotonergic drugs actions in an animal model of obsessive-compulsive disorder.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Estradiol; Estrous Cycle; Female; Fluoxetine; Obsessive-Compulsive Disorder; Ovariectomy; Ovary; Progesterone; Rats; Rats, Wistar; Selective Serotonin Reuptake Inhibitors; Serotonin Agents; Serotonin Receptor Agonists; Steroids | 2006 |
Serotonergic pre-treatments block in vitro serotonergic phase shifts of the mouse suprachiasmatic nucleus circadian clock.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Action Potentials; Animals; Circadian Rhythm; Colforsin; Dose-Response Relationship, Drug; Drug Interactions; Fluoxetine; In Vitro Techniques; Male; Mice; Neurons; Serotonin; Serotonin Agents; Serotonin Receptor Agonists; Suprachiasmatic Nucleus; Time Factors; Tryptophan | 2006 |
Enhanced reactivity of 5-HT1A receptors in the rat dorsal periaqueductal gray matter after chronic treatment with fluoxetine and sertraline: evidence from the elevated T-maze.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Analysis of Variance; Animals; Behavior, Animal; Drug Interactions; Fluoxetine; Male; Maze Learning; Periaqueductal Gray; Rats; Rats, Wistar; Reaction Time; Receptor, Serotonin, 5-HT1A; Selective Serotonin Reuptake Inhibitors; Sertraline | 2007 |
Unchanged density of 5-HT(1A) autoreceptors on the plasma membrane of nucleus raphe dorsalis neurons in rats chronically treated with fluoxetine.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Cell Membrane; Drug Interactions; Fluoxetine; Hippocampus; Male; Microscopy, Immunoelectron; Models, Neurological; Neurons; Protein Binding; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1A; Selective Serotonin Reuptake Inhibitors; Ultrasonography | 2008 |
Serotonergic activation potentiates light resetting of the main circadian clock and alters clock gene expression in a diurnal rodent.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Analysis of Variance; Animals; Behavior, Animal; Cell Cycle Proteins; Circadian Rhythm; Dose-Response Relationship, Drug; Female; Fluoxetine; Gene Expression Regulation; Hydroxyindoleacetic Acid; Light; Male; Period Circadian Proteins; Rats; Receptors, Cytoplasmic and Nuclear; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Receptor Agonists; Suprachiasmatic Nucleus | 2008 |
Antidepressant-like effects of serotonin type-3 antagonist, ondansetron: an investigation in behaviour-based rodent models.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antidepressive Agents; Behavior, Animal; Cyclohexanols; Desipramine; Dose-Response Relationship, Drug; Drug Interactions; Drug Therapy, Combination; Exploratory Behavior; Fluoxetine; Hindlimb Suspension; Male; Maze Learning; Mice; Motor Activity; Olfactory Bulb; Ondansetron; Paroxetine; Rats; Rats, Wistar; Serotonin 5-HT3 Receptor Agonists; Serotonin 5-HT3 Receptor Antagonists; Stress, Psychological; Venlafaxine Hydrochloride | 2008 |
Lasting syndrome of depression produced by reduction in serotonin uptake during postnatal development: evidence from sleep, stress, and behavior.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Analysis of Variance; Animals; Animals, Newborn; Antidepressive Agents; Behavior, Animal; Choice Behavior; Citalopram; Corticosterone; Depressive Disorder; Disease Models, Animal; Fluoxetine; Food Preferences; Hypothermia; Maze Learning; Mice; Mice, Knockout; Serotonin; Serotonin Plasma Membrane Transport Proteins; Sleep Wake Disorders; Spectrum Analysis; Stress, Physiological; Wakefulness | 2008 |
Glucocorticoid receptor antagonism augments fluoxetine-induced downregulation of the 5-HT transporter.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Analysis of Variance; Animals; Autoradiography; Brain; Citalopram; Densitometry; Down-Regulation; Fluoxetine; In Situ Hybridization; Male; Rats; Receptor, Serotonin, 5-HT1A; Receptors, Glucocorticoid; RNA, Messenger; Selective Serotonin Reuptake Inhibitors; Serotonin 5-HT1 Receptor Agonists; Serotonin Plasma Membrane Transport Proteins; Steroids; Sulfones; Tritium; Tryptophan Hydroxylase | 2009 |
Insensitivity of NMRI mice to selective serotonin reuptake inhibitors in the tail suspension test can be reversed by co-treatment with 5-hydroxytryptophan.
Topics: 5-Hydroxytryptophan; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Body Temperature; Citalopram; Dose-Response Relationship, Drug; Fluoxetine; Genotype; Hindlimb Suspension; Hippocampus; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred DBA; Microdialysis; Motor Activity; Norepinephrine Plasma Membrane Transport Proteins; Prefrontal Cortex; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Receptor Agonists; Species Specificity; Tyrosine 3-Monooxygenase | 2008 |
WAY100635 prevents the changes induced by fluoxetine upon the 5-HT1A receptor functionality.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Autoradiography; Brain; Drug Interactions; Fluoxetine; Guanosine 5'-O-(3-Thiotriphosphate); Male; Piperazines; Protein Binding; Pyridines; Radioisotopes; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT1A; Selective Serotonin Reuptake Inhibitors; Serotonin Antagonists; Serotonin Receptor Agonists; Time Factors | 2008 |
Chronic reductions in serotonin transporter function prevent 5-HT1B-induced behavioral effects in mice.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Female; Fluoxetine; Globus Pallidus; Indoles; Mice; Mice, Inbred BALB C; Mice, Knockout; Motor Activity; Oxadiazoles; Piperazines; Pyridines; Receptor, Serotonin, 5-HT1B; Reflex, Startle; Serotonin 5-HT1 Receptor Agonists; Serotonin 5-HT1 Receptor Antagonists; Serotonin Plasma Membrane Transport Proteins; Substantia Nigra | 2009 |
Effect of 5-HT3 antagonists and a 5-HT(1A) agonist on fluoxetine-induced conditioned gaping reactions in rats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antiemetics; Autoreceptors; Conditioning, Psychological; Dose-Response Relationship, Drug; Fluoxetine; Isoquinolines; Lithium Chloride; Male; Nausea; Ondansetron; Palonosetron; Quinuclidines; Rats; Rats, Sprague-Dawley; Serotonin 5-HT1 Receptor Agonists; Serotonin 5-HT3 Receptor Antagonists | 2009 |
Brief constant light accelerates serotonergic re-entrainment to large shifts of the daily light/dark cycle.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Analysis of Variance; Animals; Circadian Rhythm; Cricetinae; Fluoxetine; Male; Mesocricetus; Motor Activity; Photic Stimulation; Photoperiod; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Agents; Serotonin Receptor Agonists; Time Factors; Tryptophan | 2009 |
Neurosteroids modulate compulsive and persistent behavior in rodents: implications for obsessive-compulsive disorder.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Analysis of Variance; Animals; Behavior, Animal; Dehydroepiandrosterone Sulfate; Disease Models, Animal; Dose-Response Relationship, Drug; Exploratory Behavior; Fluoxetine; Injections, Intraventricular; Male; Maze Learning; Mice; Motor Activity; Obsessive-Compulsive Disorder; Pregnanolone; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Social Isolation; Stress, Physiological | 2009 |
Role of spinal serotonergic pathways in sneeze-induced urethral continence reflex in rats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Female; Fluoxetine; Piperazines; Pressure; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1A; Receptors, Serotonin, 5-HT2; Serotonin 5-HT1 Receptor Agonists; Serotonin 5-HT1 Receptor Antagonists; Serotonin 5-HT2 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists; Sneezing; Spiro Compounds; Sulfonamides; Urethra; Urinary Incontinence, Stress | 2009 |
Neuronal nitric oxide synthase alteration accounts for the role of 5-HT1A receptor in modulating anxiety-related behaviors.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Animals, Newborn; Anxiety Disorders; CREB-Binding Protein; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Exploratory Behavior; Feeding Behavior; Fluoxetine; Gene Expression Regulation, Enzymologic; Hippocampus; Indazoles; Male; Maze Learning; Mice; Mice, Inbred C57BL; Mice, Knockout; Nitric Oxide Synthase Type I; Phosphorylation; Piperazines; Reaction Time; Receptor, Serotonin, 5-HT1A; Selective Serotonin Reuptake Inhibitors; Serotonin Antagonists; Serotonin Receptor Agonists; Time Factors | 2010 |
Role of 5-HT(1A) receptors in fluoxetine-induced lordosis inhibition.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Dose-Response Relationship, Drug; Female; Fluoxetine; Models, Animal; Ovariectomy; Piperazines; Progesterone; Pyridines; Rats; Rats, Inbred F344; Receptor, Serotonin, 5-HT1A; Selective Serotonin Reuptake Inhibitors; Serotonin 5-HT1 Receptor Agonists; Serotonin 5-HT1 Receptor Antagonists; Serotonin Antagonists; Serotonin Receptor Agonists; Sexual Behavior, Animal; Sexual Dysfunctions, Psychological; Time Factors | 2010 |
SK channel blocker apamin attenuates the effect of SSRI fluoxetine upon cell firing in dorsal raphe nucleus: a concomitant electrophysiological and electrochemical in vivo study reveals implications for modulating extracellular 5-HT.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Action Potentials; Amygdala; Analysis of Variance; Animals; Apamin; Drug Administration Routes; Drug Interactions; Electrochemistry; Electrophysiology; Fluoxetine; Male; Neurons; Potassium Channel Blockers; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Receptor Agonists; Time Factors | 2010 |
Chronic treatment with fluoxetine decreases cerebral metabolic responses to the 5-HT1A agonist 8-hydroxy-2(di-N-propylamino)tetralin and increases those to the 5-HT2A/2C agonist 1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane and to the dopaminergic agonist
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Apomorphine; Brain; Dopamine Agonists; Down-Regulation; Drug Administration Schedule; Fluoxetine; Male; Rats; Rats, Inbred F344; Receptor, Serotonin, 5-HT1A; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Selective Serotonin Reuptake Inhibitors; Serotonin Receptor Agonists; Up-Regulation | 2010 |
Differential involvement of 5-HT(1A) and 5-HT(1B/1D) receptors in human interferon-alpha-induced immobility in the mouse forced swimming test.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Buspirone; Depression; Fluoxetine; Interferon-alpha; Male; Mice; Mice, Inbred ICR; Motor Activity; Oxadiazoles; Piperazines; Pyridines; Quinoxalines; Receptor, Serotonin, 5-HT1A; Receptor, Serotonin, 5-HT1B; Receptor, Serotonin, 5-HT1D; Selective Serotonin Reuptake Inhibitors; Serotonin 5-HT1 Receptor Agonists; Serotonin 5-HT1 Receptor Antagonists; Serotonin Antagonists; Serotonin Receptor Agonists; Swimming | 2010 |
HPC-1/syntaxin 1A gene knockout mice show abnormal behavior possibly related to a disruption in 5-HTergic systems.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic Uptake Inhibitors; Amphetamines; Animals; Behavior, Animal; Desipramine; Dopamine Agonists; Dopamine Antagonists; Fluoxetine; Haloperidol; Hippocampus; Humans; Hypothalamus; Inhibition, Psychological; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Phenotype; Piperazines; Quinpirole; Receptor, Serotonin, 5-HT2A; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Plasma Membrane Transport Proteins; Serotonin Receptor Agonists; Social Behavior; Syntaxin 1 | 2010 |
Characterization of 5-HT transporter and receptor system in HeLaS3 cells by [(3)H]8-OH-DPAT and other serotonergic ligands.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Binding, Competitive; Biogenic Amines; Cocaine; Fluoxetine; HeLa Cells; Humans; Kinetics; Ligands; Paroxetine; Radioligand Assay; Receptors, Serotonin; Selective Serotonin Reuptake Inhibitors; Serotonin Plasma Membrane Transport Proteins; Vesicular Biogenic Amine Transport Proteins | 2011 |
Fluoxetine prevents 8-OH-DPAT-induced hyperphagia in Fischer inbred rats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Anorexia; Eating; Estradiol; Female; Fluoxetine; Hyperphagia; Ovariectomy; Progesterone; Rats; Rats, Inbred F344; Selective Serotonin Reuptake Inhibitors | 2011 |
Selective siRNA-mediated suppression of 5-HT1A autoreceptors evokes strong anti-depressant-like effects.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Administration, Intranasal; Animals; Antidepressive Agents; Autoreceptors; Depression; Disease Models, Animal; Drug Combinations; Drug Design; Fluoxetine; Hippocampus; Hypothermia; Infusions, Intraventricular; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Prefrontal Cortex; Receptor, Serotonin, 5-HT1A; RNA, Small Interfering; Serotonergic Neurons; Sertraline | 2012 |
Functional significance of glycogen synthase kinase-3 regulation by serotonin.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; CA1 Region, Hippocampal; CA3 Region, Hippocampal; Chromones; Fear; Fluoxetine; Freezing Reaction, Cataleptic; Gene Knock-In Techniques; Glycogen Synthase Kinase 3; Hippocampus; Male; Mice; Mice, Inbred C57BL; Morpholines; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Proto-Oncogene Proteins c-akt; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin 5-HT1 Receptor Agonists; Signal Transduction | 2012 |
5-HT(2B) receptors are required for serotonin-selective antidepressant actions.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Analysis of Variance; Animals; Bromodeoxyuridine; Cell Differentiation; Chromatography, High Pressure Liquid; Exploratory Behavior; Fluoxetine; Gene Expression Regulation; Hippocampus; Hypothermia; Ki-67 Antigen; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Microdialysis; Neurogenesis; Reaction Time; Receptor, Serotonin, 5-HT2B; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Plasma Membrane Transport Proteins; Serotonin Receptor Agonists; Time Factors; Transcription Factors | 2012 |
Acute 5-HT₁A autoreceptor knockdown increases antidepressant responses and serotonin release in stressful conditions.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Autoreceptors; Behavior, Animal; Disease Models, Animal; Fluoxetine; Gene Knockdown Techniques; Hypothermia; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Microdialysis; Prefrontal Cortex; Raphe Nuclei; Receptor, Serotonin, 5-HT1A; RNA, Messenger; RNA, Small Interfering; Selective Serotonin Reuptake Inhibitors; Serotonin; Stress, Psychological | 2013 |
Estradiol accelerates the effects of fluoxetine on serotonin 1A receptor signaling.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenocorticotropic Hormone; Animals; Drug Interactions; Estradiol; Female; Fluoxetine; Hippocampus; Oxytocin; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1A; Selective Serotonin Reuptake Inhibitors; Serotonin Receptor Agonists; Signal Transduction | 2013 |
Sex- and endocrine-stage-differences in middle-aged rats in an animal model of OCD.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Age Factors; Analysis of Variance; Animals; Disease Models, Animal; Endocrine System; Estradiol; Exploratory Behavior; Female; Fluoxetine; Follicle Stimulating Hormone; Luteinizing Hormone; Male; Maze Learning; Obsessive-Compulsive Disorder; Psychomotor Performance; Rats; Rotarod Performance Test; Selective Serotonin Reuptake Inhibitors; Serotonin Receptor Agonists; Sex Characteristics | 2013 |
The effect of serotonergic system on nociceptin/orphanin FQ induced food intake in chicken.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aminopyridines; Animals; Chickens; Feeding Behavior; Fenclonine; Fluoxetine; Indoles; Injections, Intraventricular; Male; Nociceptin; Opioid Peptides; Receptor, Serotonin, 5-HT2C; Serotonin; Serotonin 5-HT2 Receptor Antagonists; Serotonin Antagonists | 2013 |
BDNF overexpression in mouse hippocampal astrocytes promotes local neurogenesis and elicits anxiolytic-like activities.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antidepressive Agents, Second-Generation; Anxiety; Astrocytes; Behavior, Animal; Brain-Derived Neurotrophic Factor; Depression; Fluoxetine; Gene Expression; Hippocampus; Male; Mice; Neurogenesis; Piperazines; Pyridines; Serotonin Antagonists; Serotonin Receptor Agonists | 2013 |
Lower anxiogenic effects of serotonin agonists are associated with lower activation of amygdala and lateral orbital cortex in adolescent male rats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Age Factors; Amygdala; Animals; Anxiety; Behavior, Animal; Dose-Response Relationship, Drug; Fluoxetine; Male; Piperazines; Prefrontal Cortex; Rats; Serotonin; Serotonin Receptor Agonists | 2013 |
Estradiol potentiates 8-OH-DPAT-induced sumoylation of 5-HT₁A receptor: characterization and subcellular distribution of sumoylated 5-HT₁A receptors.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Brain; Cell Membrane; Drug Synergism; Endoplasmic Reticulum; Estradiol; Estrogens; Female; Fluoxetine; Golgi Apparatus; Protein Processing, Post-Translational; Rats; Receptor, Serotonin, 5-HT1A; Receptors, G-Protein-Coupled; Selective Serotonin Reuptake Inhibitors; Serotonin 5-HT1 Receptor Agonists; Subcellular Fractions; Sumoylation | 2013 |
Modulation of the subthalamic nucleus activity by serotonergic agents and fluoxetine administration.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Action Potentials; Animals; Ethylamines; Fenclonine; Fluoxetine; Indoles; Male; Motor Activity; Neurons; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1A; Receptor, Serotonin, 5-HT2C; Selective Serotonin Reuptake Inhibitors; Serotonin 5-HT1 Receptor Agonists; Serotonin 5-HT2 Receptor Agonists; Serotonin Agents; Serotonin Antagonists; Subthalamic Nucleus | 2014 |
Mechanism of action of the bimodal antidepressant vilazodone: evidence for serotonin1A-receptor-mediated auto-augmentation of extracellular serotonin output.
Topics: 5-Hydroxytryptophan; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antidepressive Agents; Benzofurans; Brain; Citalopram; Dose-Response Relationship, Drug; Drug Interactions; Extracellular Space; Fluoxetine; Indoles; Male; Paroxetine; Piperazines; Pyridines; Rats, Wistar; Receptor, Serotonin, 5-HT1A; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin 5-HT1 Receptor Agonists; Serotonin Antagonists; Serotonin Receptor Agonists; Vilazodone Hydrochloride | 2014 |
Expression of the 5-HT1A serotonin receptor in the hippocampus is required for social stress resilience and the antidepressant-like effects induced by the nicotinic partial agonist cytisine.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Alkaloids; Animals; Antidepressive Agents; Azocines; Disease Models, Animal; Drug Synergism; Fluoxetine; Gene Expression Regulation; HEK293 Cells; Hindlimb Suspension; Hippocampus; Humans; Interpersonal Relations; Male; Mice; Mice, Inbred C57BL; Motor Activity; Quinolizines; Receptor, Serotonin, 5-HT1A; Selective Serotonin Reuptake Inhibitors; Serotonin Receptor Agonists; Stress, Psychological | 2015 |
Duloxetine and 8-OH-DPAT, but not fluoxetine, reduce depression-like behaviour in an animal model of chronic neuropathic pain.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic Neurons; Analgesics; Animals; Antidepressive Agents; Behavior, Animal; Chronic Disease; Depression; Duloxetine Hydrochloride; Fluoxetine; Hyperalgesia; Male; Neuralgia; Norepinephrine; Rats, Wistar; Serotonergic Neurons; Serotonin | 2016 |
The absence of 5-HT
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Anhedonia; Animals; Antidepressive Agents, Second-Generation; Anxiety; Autoreceptors; Axl Receptor Tyrosine Kinase; Brain-Derived Neurotrophic Factor; Depression; Fluoxetine; Guanosine 5'-O-(3-Thiotriphosphate); Hippocampus; Hypothermia; Mice; Mice, Knockout; Neuronal Plasticity; Olfactory Bulb; Proto-Oncogene Proteins; Receptor Protein-Tyrosine Kinases; Receptor, Serotonin, 5-HT1A; Receptor, trkB; Receptors, Serotonin, 5-HT4 | 2016 |
Serotonin and arginine-vasopressin mediate sex differences in the regulation of dominance and aggression by the social brain.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aggression; Animals; Arginine Vasopressin; Behavior, Animal; Female; Fluoxetine; Hypothalamus; Male; Mesocricetus; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Receptor Agonists; Sex Characteristics; Social Dominance | 2016 |
Circadian behavior of adult mice exposed to stress and fluoxetine during development.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Behavior, Animal; Circadian Rhythm; Female; Fluoxetine; Light; Male; Mice; Motor Activity; Photoperiod; Pregnancy; Pregnancy Complications; Prenatal Exposure Delayed Effects; Selective Serotonin Reuptake Inhibitors; Stress, Psychological | 2017 |
Positive regulation of raphe serotonin neurons by serotonin 2B receptors.
Topics: 3,4-Methylenedioxyamphetamine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Action Potentials; Amphetamines; Animals; Body Temperature; Central Nervous System Sensitization; Female; Fluoxetine; Indoles; Male; Mice; Mice, Knockout; Mice, Transgenic; Neurogenesis; Prepulse Inhibition; Raphe Nuclei; Receptor, Serotonin, 5-HT2B; Serotonergic Neurons; Serotonin 5-HT2 Receptor Agonists; Thiophenes; Transcription Factors | 2018 |
Deep brain stimulation and fluoxetine exert different long-term changes in the serotonergic system.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Brain; Deep Brain Stimulation; Fluoxetine; Hippocampus; Iodine Radioisotopes; Pindolol; Prefrontal Cortex; Radioligand Assay; Rats; Receptor, Serotonin, 5-HT1A; Receptor, Serotonin, 5-HT1B; Serotonin; Serotonin Plasma Membrane Transport Proteins; Time Factors; Tritium | 2018 |
The effect of acute and repeated administration of buspirone, 8-OHDPAT and fluoxetine on haloperidol-induced extrapyramidal symptoms.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Buspirone; Catalepsy; Fluoxetine; Haloperidol; Male; Pyramidal Cells; Rats; Rats, Wistar | 2019 |
Perinatal fluoxetine exposure disrupts the circadian response to a phase-shifting challenge in female rats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adaptation, Psychological; Animals; Antidepressive Agents; Circadian Rhythm; Female; Fluoxetine; Rats; Rats, Transgenic; Rats, Wistar; Selective Serotonin Reuptake Inhibitors; Serotonin; Suprachiasmatic Nucleus | 2020 |
Serotonergic modulation of basolateral amygdala nucleus in the extinction of reward-driven learning: The role of 5-HT bioavailability and 5-HT
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Basolateral Nuclear Complex; Biological Availability; Conditioning, Operant; Extinction, Psychological; Fluoxetine; Male; Piperazines; Pyridines; Rats; Rats, Long-Evans; Receptor, Serotonin, 5-HT1A; Reward; Serotonin; Serotonin 5-HT1 Receptor Agonists; Serotonin 5-HT1 Receptor Antagonists | 2021 |
Tonic serotonergic input increases the burst firing mode and diminishes the firing rate of reticular thalamic nucleus neurons through 5-HT1A receptors activation in anesthetized rats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Fluoxetine; GABAergic Neurons; Humans; Rats; Receptor, Serotonin, 5-HT1A; Thalamic Nuclei | 2022 |
Requirement of hippocampal DG nNOS-CAPON dissociation for the anxiolytic and antidepressant effects of fluoxetine.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adaptor Proteins, Signal Transducing; Animals; Anti-Anxiety Agents; Antidepressive Agents; Fluoxetine; Hippocampus; Mice; Nitric Oxide Synthase Type I | 2022 |
Memory and anxiety-like behavior of rats in the plus-maze discriminative avoidance task: Role of serotonergic transmission in the basolateral amygdala.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Anxiety; Avoidance Learning; Basolateral Nuclear Complex; Fluoxetine; Ketanserin; Male; Rats; Rats, Wistar; Serotonin | 2023 |