Compounds > 8-hydroxy-2-(di-n-propylamino)tetralin

8-hydroxy-2-(di-n-propylamino)tetralin and donepezil

8-hydroxy-2-(di-n-propylamino)tetralin has been researched along with donepezil in 4 studies

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (75.00)24.3611
2020's1 (25.00)2.80

Authors

AuthorsStudies
Belyakov, S; Dambrova, M; Kazoka, H; Kuznecovs, J; Lebedev, A; Liepinsh, E; Mishnev, A; Orlova, N; Ponomaryov, Y; Vavers, E; Veinberg, G; Vikainis, S; Vilskersts, R; Vorona, M; Zvejniece, L1
Fu, Y; Gong, Q; Huang, J; Huang, Y; Li, J; Li, X; Mao, F; Wang, H; Xu, Y; You, H; Zhang, D; Zhang, H; Zhu, J1
Hu, XJ; Kehr, J; Ogren, SO; Osborne, P; Stenfors, C; Wang, FH; Yoshitake, T1
Haji, A; Kimura, S; Ohi, Y1

Other Studies

4 other study(ies) available for 8-hydroxy-2-(di-n-propylamino)tetralin and donepezil

ArticleYear
Synthesis and biological evaluation of 2-(5-methyl-4-phenyl-2-oxopyrrolidin-1-yl)-acetamide stereoisomers as novel positive allosteric modulators of sigma-1 receptor.
    Bioorganic & medicinal chemistry, 2013, May-15, Volume: 21, Issue:10

    Topics: Acetamides; Allosteric Regulation; Animals; Rats; Rats, Wistar; Receptors, sigma; Sigma-1 Receptor; Stereoisomerism; Structure-Activity Relationship

2013
The novel therapeutic strategy of vilazodone-donepezil chimeras as potent triple-target ligands for the potential treatment of Alzheimer's disease with comorbid depression.
    European journal of medicinal chemistry, 2022, Feb-05, Volume: 229

    Topics: Acetylcholinesterase; Alzheimer Disease; Animals; Antidepressive Agents; Binding Sites; Brain; Cholinesterase Inhibitors; Depression; Donepezil; Drug Design; Half-Life; Humans; Ligands; Mice; Molecular Docking Simulation; Rats; Rats, Sprague-Dawley; Serotonin Plasma Membrane Transport Proteins; Structure-Activity Relationship; Vilazodone Hydrochloride

2022
The selective 5-HT(1A) receptor antagonist NAD-299 increases acetylcholine release but not extracellular glutamate levels in the frontal cortex and hippocampus of awake rat.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2010, Volume: 20, Issue:7

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Acetylcholine; Animals; Area Under Curve; Benzopyrans; Cholinesterase Inhibitors; Donepezil; Dose-Response Relationship, Drug; Extracellular Fluid; Frontal Lobe; Glutamic Acid; Hippocampus; Indans; Male; Microdialysis; Neostigmine; Piperidines; Rats; Rats, Sprague-Dawley; Serotonin Antagonists; Serotonin Receptor Agonists; Wakefulness

2010
Effects of cholinesterase inhibitors and serotonin-1A receptor agonists on morphine-induced ventilatory depression and antinociception in rats.
    European journal of pharmacology, 2013, Mar-05, Volume: 703, Issue:1-3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Analgesia; Animals; Buspirone; Cholinesterase Inhibitors; Donepezil; Indans; Male; Morphine; Pain; Physostigmine; Piperidines; Rats; Rats, Wistar; Respiratory Insufficiency; Serotonin 5-HT1 Receptor Agonists

2013