8-hydroxy-2-(di-n-propylamino)tetralin has been researched along with dizocilpine maleate in 31 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 12 (38.71) | 18.2507 |
| 2000's | 12 (38.71) | 29.6817 |
| 2010's | 7 (22.58) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Anzini, M; Brogi, S; Butini, S; Campiani, G; Cappelli, A; Caselli, G; Castriconi, F; Gemma, S; Giordani, A; Giorgi, G; Giuliani, G; Lanza, M; Letari, O; Makovec, F; Manini, M; Mennuni, L; Valenti, S | 1 |
| Belyakov, S; Dambrova, M; Kazoka, H; Kuznecovs, J; Lebedev, A; Liepinsh, E; Mishnev, A; Orlova, N; Ponomaryov, Y; Vavers, E; Veinberg, G; Vikainis, S; Vilskersts, R; Vorona, M; Zvejniece, L | 1 |
| Kelder, D; Rényi, L; Ross, SB | 1 |
| Ensler, K; Evenden, J; Möller, KA; Rényi, L | 1 |
| Carlsson, A; Carlsson, M; Svensson, A | 1 |
| Bengtsson, A; Cortizo, L; Jackson, DM; Johansson, C; Ross, SB | 1 |
| Dourish, CT; McLenachan, AP; Stanhope, KJ | 1 |
| Czyrak, A; Fijał, K; Maćkowiak, M; Michalska, B; Wedzony, K | 1 |
| Matsuyama, S; Nei, K; Tanaka, C | 1 |
| Albers, DS; Moy, LY; Sonsalla, PK | 1 |
| Barrett, JE; Vanover, KE | 1 |
| Bagdy, G; Filakovszky, J; Gerber, K | 1 |
| Ebert, U; Fuchs, E; Kole, MH; Paulus, W; Ziemann, U | 1 |
| Kaneko, T; Kikusui, T; Tonohiro, T | 1 |
| Bonfante, V; Dall'Olio, R; Gaggi, R; Gandolfi, O | 1 |
| Dall'Olio, R; Gaggi, R; Gandolfi, O | 1 |
| Bagdy, G; Filakovszky, J; Halasz, P; Kantor, S | 1 |
| Ago, Y; Baba, A; Matsuda, T; Sakaue, M | 1 |
| van den Buuse, M | 1 |
| Lawrence, AJ; Martin, S; van den Buuse, M | 1 |
| Elvander, E; Lüttgen, M; Madjid, N; Ogren, SO | 1 |
| Forsberg, T; Gabrielsson, J; Martinsson, S; Pozarek, S; Ross, SB; Visser, SA | 1 |
| Bubeníková-Valesová, V; Horácek, J; Pálenícek, T; Votava, M | 1 |
| Bishop, C; Dupre, KB; Eskow, KL; Klioueva, A; Lormand, L; Negron, GE; Park, JY; Steiniger, A | 1 |
| Meneses, A; Perez-García, G | 1 |
| Gronier, B | 1 |
| Congleton, MR; Duncan, MJ | 1 |
| Gogos, A; Kwek, P; van den Buuse, M | 1 |
| Acher, FC; Gruca, P; Lasoń-Tyburkiewicz, M; Papp, M; Pilc, A; Sławińska, A; Wierońska, JM | 1 |
| Beloushko, E; Bourbia, N; Pertovaara, A; Sagalajev, B; Wei, H | 1 |
| Biel, D; Radscheit, K; van den Buuse, M | 1 |
31 other study(ies) available for 8-hydroxy-2-(di-n-propylamino)tetralin and dizocilpine maleate
| Article | Year |
|---|---|
Synthesis and structure-activity relationship studies in serotonin 5-HT(1A) receptor agonists based on fused pyrrolidone scaffolds.
Topics: Animals; Area Under Curve; Humans; Intestinal Absorption; Ligands; Male; Metabolic Clearance Rate; Models, Chemical; Models, Molecular; Molecular Structure; Protein Binding; Protein Structure, Tertiary; Pyrrolidinones; Radioligand Assay; Receptor, Serotonin, 5-HT1A; Receptors, Serotonin, 5-HT3; Serotonin 5-HT1 Receptor Agonists; Structure-Activity Relationship | 2013 |
Synthesis and biological evaluation of 2-(5-methyl-4-phenyl-2-oxopyrrolidin-1-yl)-acetamide stereoisomers as novel positive allosteric modulators of sigma-1 receptor.
Topics: Acetamides; Allosteric Regulation; Animals; Rats; Rats, Wistar; Receptors, sigma; Sigma-1 Receptor; Stereoisomerism; Structure-Activity Relationship | 2013 |
N-methyl-D-aspartate receptor antagonists counteract the long lasting 5-HT1A receptor-induced attenuation of postsynaptic responses in the rat in vivo.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Behavior, Animal; Corticosterone; Dizocilpine Maleate; Ion Channels; Male; Phencyclidine; Piperazines; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Serotonin; Shivering; Synapses | 1992 |
The non-competitive NMDA receptor antagonist (+)MK-801 counteracts the long-lasting attenuation of the hypothermic response induced by acute doses of 8-OH-DPAT in the rat.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Body Temperature; Dizocilpine Maleate; Injections, Subcutaneous; Male; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 1992 |
Synergistic interactions between the NMDA antagonist dizocilpine and the preferential dopamine autoreceptor antagonists (+)-AJ 76 and (+)-UH 232 with regard to locomotor stimulation in monoamine-depleted mice.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Dizocilpine Maleate; Dopamine Antagonists; Drug Synergism; Locomotion; Male; Mice; Motor Activity; N-Methylaspartate; Tetrahydronaphthalenes | 1991 |
Development of tolerance to 8-OH-DPAT induced blockade of acquisition of a passive avoidance response.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Avoidance Learning; Depression, Chemical; Dizocilpine Maleate; Drug Tolerance; Male; Memory; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Receptors, Serotonin; Serotonin Antagonists; Stereoisomerism | 1994 |
Dissociation between cognitive and motor/motivational deficits in the delayed matching to position test: effects of scopolamine, 8-OH-DPAT and EAA antagonists.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Cognition; Conditioning, Operant; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Male; Motor Activity; Muscarinic Antagonists; Pipecolic Acids; Rats; Rats, Sprague-Dawley; Scopolamine; Scopolamine Derivatives; Serotonin Receptor Agonists | 1995 |
Single doses of MK-801, a non-competitive antagonist of NMDA receptors, increase the number of 5-HT1A serotonin receptors in the rat brain.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Autoradiography; Brain; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Male; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Receptors, Serotonin; Serotonin; Serotonin Receptor Agonists | 1997 |
Regulation of GABA release via NMDA and 5-HT1A receptors in guinea pig dentate gyrus.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Calcium; Chromatography, High Pressure Liquid; Dentate Gyrus; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; gamma-Aminobutyric Acid; Glutamic Acid; Guinea Pigs; Magnesium; Male; N-Methylaspartate; Neurons; Piperazines; Receptors, N-Methyl-D-Aspartate; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Antagonists; Serotonin Receptor Agonists; Tetrodotoxin | 1997 |
Lowering ambient or core body temperature elevates striatal MPP+ levels and enhances toxicity to dopamine neurons in MPTP-treated mice.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Body Temperature; Corpus Striatum; Dizocilpine Maleate; Dopamine; Dopamine Agents; Excitatory Amino Acid Antagonists; Methamphetamine; Mice; MPTP Poisoning; Nerve Degeneration; Neurons; Neurotoxins; Serotonin Receptor Agonists; Tyrosine 3-Monooxygenase | 1998 |
An automated learning and memory model in mice: pharmacological and behavioral evaluation of an autoshaped response.
Topics: 4-Aminopyridine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Indoles; Learning; Male; Memory; Mice; Models, Psychological; Muscarinic Antagonists; Pyridines; Scopolamine; Serotonin Receptor Agonists | 1998 |
A serotonin-1A receptor agonist and an N-methyl-D-aspartate receptor antagonist oppose each others effects in a genetic rat epilepsy model.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Action Potentials; Animals; Brain Chemistry; Disease Models, Animal; Dizocilpine Maleate; Epilepsy, Absence; Excitatory Amino Acid Antagonists; Injections, Intraventricular; Male; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Receptor Agonists | 1999 |
Changes in 5-HT1A and NMDA binding sites by a single rapid transcranial magnetic stimulation procedure in rats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amygdala; Animals; Autoradiography; Brain Chemistry; Cerebral Cortex; Dentate Gyrus; Depression; Dizocilpine Maleate; Electric Stimulation; Excitatory Amino Acid Antagonists; Female; Iodine Radioisotopes; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Receptor Agonists; Transcranial Magnetic Stimulation; Tritium | 1999 |
The allocentric place discrimination task is selectively and highly dependent on the central muscarinic system in rats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Brain; Diazepam; Discrimination Learning; Dizocilpine Maleate; Flumazenil; Male; Mecamylamine; Ondansetron; Rats; Rats, Inbred F344; Receptors, Muscarinic; Scopolamine; Swimming | 2000 |
The non-competitive NMDA receptor blocker dizocilpine potentiates serotonergic function.
Topics: 2-Amino-5-phosphonovalerate; 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Benzazepines; Dizocilpine Maleate; Dopamine Antagonists; Excitatory Amino Acid Antagonists; Ketanserin; Male; Motor Activity; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2A; Receptors, Dopamine D1; Receptors, N-Methyl-D-Aspartate; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin; Serotonin Receptor Agonists; Sulpiride | 1999 |
Blockade of the serotonergic system counteracts the dizocilpine-induced changes in dopaminergic function.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Behavior, Animal; Dizocilpine Maleate; Dopamine; Dopamine Agonists; Excitatory Amino Acid Antagonists; Grooming; Ketanserin; Male; Methysergide; Motor Activity; Quinpirole; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Antagonists; Serotonin Receptor Agonists; Stereotyped Behavior | 2000 |
8-OH-DPAT and MK-801 affect epileptic activity independently of vigilance.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Attention; Behavior, Animal; Dizocilpine Maleate; Epilepsy; Injections, Intraventricular; Male; Rats; Sleep | 2001 |
The 5-HT1A receptor agonist MKC-242 reverses isolation rearing-induced deficits of prepulse inhibition in mice.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Acoustic Stimulation; Administration, Oral; Animals; Apomorphine; Dioxanes; Dioxoles; Dizocilpine Maleate; Drug Interactions; Male; Mice; Piperazines; Pyridines; Reflex, Startle; Risperidone; Serotonin 5-HT1 Receptor Agonists; Serotonin Antagonists; Social Isolation | 2003 |
Prepulse inhibition of acoustic startle in spontaneously hypertensive rats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Acoustic Stimulation; Adrenergic Agents; Amphetamine; Analysis of Variance; Animals; Apomorphine; Disease Models, Animal; Dizocilpine Maleate; Dopamine Agonists; Dose-Response Relationship, Radiation; Excitatory Amino Acid Antagonists; Hypertension; Male; Neural Inhibition; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Rats, Sprague-Dawley; Reflex, Acoustic; Reflex, Startle; Serotonin Receptor Agonists; Species Specificity | 2004 |
Prepulse inhibition in fawn-hooded rats: increased sensitivity to 5-HT1A receptor stimulation.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamine; Animals; Apomorphine; Dizocilpine Maleate; Dopamine Agonists; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Neural Inhibition; Rats; Rats, Inbred Strains; Rats, Inbred WKY; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1A; Reflex, Startle; Serotonin Receptor Agonists; Species Specificity | 2004 |
Analysis of the role of 5-HT1A receptors in spatial and aversive learning in the rat.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Analysis of Variance; Animals; Avoidance Learning; Behavior, Animal; Benzopyrans; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Antagonists; Male; Maze Learning; Muscarinic Antagonists; Piperazines; Pyridines; Rats; Rats, Sprague-Dawley; Reaction Time; Receptor, Serotonin, 5-HT1A; Scopolamine; Serotonin Antagonists; Serotonin Receptor Agonists; Spatial Behavior; Time Factors | 2005 |
Rapid and long-lasting tolerance to clomethiazole-induced hypothermia in the rat.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Bicuculline; Body Temperature; Chlormethiazole; Dizocilpine Maleate; Drug Tolerance; Excitatory Amino Acid Antagonists; GABA Agonists; GABA Antagonists; GABA Modulators; Hypothermia; Injections, Subcutaneous; Male; Muscimol; Picrotoxin; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Serotonin 5-HT1 Receptor Agonists; Serotonin Receptor Agonists; Time Factors | 2005 |
The opposite effect of a low and a high dose of serotonin-1A agonist on behavior induced by MK-801.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Acoustic Stimulation; Analysis of Variance; Animals; Behavior, Animal; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Male; Motor Activity; Neural Inhibition; Rats; Rats, Wistar; Reflex, Startle; Serotonin Receptor Agonists | 2007 |
Effects of coincident 5-HT1A receptor stimulation and NMDA receptor antagonism on L-DOPA-induced dyskinesia and rotational behaviors in the hemi-parkinsonian rat.
Topics: 3,4-Dihydroxyphenylacetic Acid; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Corpus Striatum; Dizocilpine Maleate; Dopamine; Dose-Response Relationship, Drug; Dyskinesia, Drug-Induced; Excitatory Amino Acid Antagonists; Hydroxyindoleacetic Acid; Injections, Intraperitoneal; Levodopa; Male; Medial Forebrain Bundle; Motor Activity; Motor Skills; Parkinsonian Disorders; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1A; Receptors, N-Methyl-D-Aspartate; Serotonin; Serotonin Receptor Agonists; Stereotyped Behavior | 2008 |
Ex vivo study of 5-HT(1A) and 5-HT(7) receptor agonists and antagonists on cAMP accumulation during memory formation and amnesia.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amnesia; Animals; Behavior, Animal; Cholinergic Antagonists; Cyclic AMP; Dizocilpine Maleate; Enzyme-Linked Immunosorbent Assay; Excitatory Amino Acid Antagonists; Hippocampus; Learning; Male; Memory; Phenols; Piperazines; Pyrazoles; Pyridines; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT1A; Receptors, Serotonin; Scopolamine; Serotonin Antagonists; Serotonin Receptor Agonists; Sulfonamides; Tetrahydronaphthalenes | 2008 |
Involvement of glutamate neurotransmission and N-methyl-d-aspartate receptor in the activation of midbrain dopamine neurons by 5-HT1A receptor agonists: an electrophysiological study in the rat.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Analysis of Variance; Animals; Dizocilpine Maleate; Dopamine; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; GABA Agents; Glutamic Acid; Male; Neurons; Organophosphonates; Piperazines; Prefrontal Cortex; Pyridines; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Synaptic Transmission; Ventral Tegmental Area | 2008 |
Neural mechanisms mediating circadian phase resetting by activation of 5-HT(7) receptors in the dorsal raphe: roles of GABAergic and glutamatergic neurotransmission.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Bicuculline; Circadian Rhythm; Cricetinae; Dizocilpine Maleate; Drug Administration Schedule; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Male; Mesocricetus; Microinjections; Muscimol; N-Methylaspartate; Raphe Nuclei; Receptors, Serotonin; Serotonin Receptor Agonists; Synaptic Transmission | 2010 |
The role of estrogen and testosterone in female rats in behavioral models of relevance to schizophrenia.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Dizocilpine Maleate; Estrogens; Female; Ovariectomy; Psychomotor Agitation; Random Allocation; Rats; Reflex, Startle; Schizophrenia; Testosterone | 2012 |
The antipsychotic-like effects of the mGlu group III orthosteric agonist, LSP1-2111, involves 5-HT₁A signalling.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aminobutyrates; Amphetamines; Animals; Antipsychotic Agents; Cyclohexanes; Dextroamphetamine; Disease Models, Animal; Dizocilpine Maleate; Dose-Response Relationship, Drug; Male; Mice; Phosphinic Acids; Piperazines; Psychotic Disorders; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT1A; Receptors, Metabotropic Glutamate; Signal Transduction | 2013 |
Bidirectional amygdaloid control of neuropathic hypersensitivity mediated by descending serotonergic pathways acting on spinal 5-HT3 and 5-HT1A receptors.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amygdala; Animals; Dizocilpine Maleate; Glutamic Acid; Male; Neuralgia; Ondansetron; Pain Measurement; Peripheral Nervous System Diseases; Piperazines; Pyridines; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT1A; Receptors, N-Methyl-D-Aspartate; Receptors, Serotonin, 5-HT3; Serotonin 5-HT1 Receptor Agonists; Serotonin 5-HT1 Receptor Antagonists; Serotonin 5-HT3 Receptor Agonists; Serotonin 5-HT3 Receptor Antagonists; Spinal Cord | 2015 |
Does genetic BDNF deficiency in rats interact with neurotransmitter control of prepulse inhibition? Implications for schizophrenia.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Analysis of Variance; Animals; Brain-Derived Neurotrophic Factor; Cohort Studies; Dizocilpine Maleate; Dose-Response Relationship, Drug; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Female; Male; Mesylates; Mutation; Neurotransmitter Agents; Prepulse Inhibition; Pyridines; Pyrroles; Rats; Rats, Mutant Strains; Serotonin Receptor Agonists | 2017 |