8-hydroxy-2-(di-n-propylamino)tetralin and dihydroxyphenylalanine

8-hydroxy-2-(di-n-propylamino)tetralin has been researched along with dihydroxyphenylalanine in 27 studies

Research

Studies (27)

TimeframeStudies, this research(%)All Research%
pre-19907 (25.93)18.7374
1990's14 (51.85)18.2507
2000's6 (22.22)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Carlsson, A; Hoffmann, WE; Ljung, E; Lum, JT; Piercey, MF; Svensson, K1
Bolaños, FJ; Fattaccini, CM; Gozlan, H; Haj-Dahmane, S; Hamon, M; Lanfumey, L; Laporte, AM; Schechter, LE1
Andén, NE; Björk, L; Cornfield, LJ; Hacksell, U; Hillver, SE; Lewander, T; Nelson, DL1
Ahlenius, S; Larsson, K; Wijkström, A1
Ahlenius, S; Hillegaart, V; Wijkström, A2
Andén, NE; Björk, L; Hacksell, U; Karlsson, A; Pettersson, C1
Carlsson, A; Fredriksson, K; Grol, CJ; Hacksell, U; Johansson, AM; Sundell, S; Svensson, K1
Andén, NE; Björk, L; Hacksell, U; Hillver, SE; Li, YL; Ross, S; Svensson, B1
Ahlenius, S; Hillegaart, V; Hjorth, S1
Hjorth, S; Magnusson, T1
Andén, NE; Björk, L; Hacksell, U; Höök, BB; Nelson, DL1
Ahlenius, S1
Andén, NE; Björk, L; Hacksell, U; Mellin, C1
Andersson, B; Arvidsson, LE; Carlsson, A; Clark, D; Hacksell, U; Hjorth, S; Johansson, AM; Sanchez, D; Svensson, K; Wikström, H1
Andersson, B; Arvidsson, LE; Carlsson, A; Clark, D; Hacksell, U; Hjorth, S; Johansson, AM; Nilsson, JL; Sanchez, D; Svensson, K1
Cortizo, L; Hacksell, U; Lewander, T; Liu, Y; Svensson, BE; Yu, H1
Hacksell, U; Lewander, T; Liu, Y; Yu, H1
Eaton, MJ; Goudreau, JL; Lookingland, KJ; Moore, KE; Tian, Y1
Eriksson, H; Hu, PS; Jackson, DM; Jerning, E; Johansson, L; Kelder, D; Larsson, LG; Mohell, N; Rényi, L; Ross, SB; Sohn, D; Thorberg, SO; Wallsten, C; Westlind-Danielsson, A1
Ahlenius, S; Henriksson, I; Magnusson, O; Salmi, P1
Liang, SL; Pan, JT1
Ahlenius, S; Kaur, P1
Ahlenius, S; Hillegaart, V; Magnusson, O1
Esteban, S; García-Sevilla, JA; Sastre-Coll, A1
Esteban, S; García-Sevilla, JA; Miralles, A; Moranta, D; Sastre-Coll, A1
Esteban, S; García-Sevilla, JA; Moranta, D1

Other Studies

27 other study(ies) available for 8-hydroxy-2-(di-n-propylamino)tetralin and dihydroxyphenylalanine

ArticleYear
Antagonism of cocaine's pharmacological effects by the stimulant dopaminergic antagonists, (+)-AJ76 and (+)-UH232.
    Brain research, 1992, Aug-21, Volume: 588, Issue:2

    Topics: 3,4-Dihydroxyphenylacetic Acid; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Behavior, Animal; Brain Chemistry; Cocaine; Dihydroxyphenylalanine; Dopamine; Dopamine Antagonists; Electrophysiology; Homovanillic Acid; Male; Microelectrodes; Motor Activity; Rats; Rats, Sprague-Dawley; Tetrahydronaphthalenes

1992
Alterations of central serotoninergic and dopaminergic neurotransmission in rats chronically treated with ipsapirone: biochemical and electrophysiological studies.
    The Journal of pharmacology and experimental therapeutics, 1990, Volume: 255, Issue:3

    Topics: 3,4-Dihydroxyphenylacetic Acid; 5-Hydroxytryptophan; 8-Hydroxy-2-(di-n-propylamino)tetralin; Adenylyl Cyclases; Animals; Autoradiography; Behavior, Animal; Binding Sites; Biogenic Amines; Body Weight; Brain; Brain Stem; Dihydroxyphenylalanine; Dopamine; Drug Administration Schedule; Electrophysiology; Hippocampus; Homovanillic Acid; Hydroxyindoleacetic Acid; Male; Membranes; Neurons; Pyrimidines; Raphe Nuclei; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Synaptic Transmission; Tetrahydronaphthalenes; Time Factors

1990
Pharmacology of the novel 5-hydroxytryptamine1A receptor antagonist (S)-5-fluoro-8-hydroxy-2-(dipropylamino)tetralin: inhibition of (R)-8-hydroxy-2-(dipropylamino)tetralin-induced effects.
    The Journal of pharmacology and experimental therapeutics, 1991, Jul-01, Volume: 258, Issue:1

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Behavior, Animal; Brain; Dihydroxyphenylalanine; Dose-Response Relationship, Drug; Male; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin; Tetrahydronaphthalenes

1991
Behavioral and biochemical effects of the 5-HT1A receptor agonists flesinoxan and 8-OH-DPAT in the rat.
    European journal of pharmacology, 1991, Aug-06, Volume: 200, Issue:2-3

    Topics: 5-Hydroxytryptophan; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Behavior, Animal; Biogenic Monoamines; Carboxy-Lyases; Dihydroxyphenylalanine; Male; Motor Activity; Piperazines; Prosencephalon; Rats; Rats, Inbred Strains; Receptors, Serotonin; Reserpine; Sexual Behavior, Animal; Tetrahydronaphthalenes

1991
Increased dopamine turnover in the ventral striatum by 8-OH-DPAT administration in the rat.
    The Journal of pharmacy and pharmacology, 1990, Volume: 42, Issue:4

    Topics: 5-Hydroxytryptophan; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Biotransformation; Corpus Striatum; Dihydroxyphenylalanine; Dopamine; Male; Methoxydimethyltryptamines; Naphthalenes; Piperazines; Rats; Rats, Inbred Strains; Tetrahydronaphthalenes

1990
(R)- and (S)-5-hydroxy-2-(dipropylamino)tetralin (5-OH DPAT): assessment of optical purities and dopaminergic activities.
    Chirality, 1990, Volume: 2, Issue:2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Brain; Brain Chemistry; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Dihydroxyphenylalanine; Dopamine Agents; In Vitro Techniques; Male; Naphthalenes; Rats; Rats, Inbred Strains; Receptors, Dopamine; Stereoisomerism; Tetrahydronaphthalenes; Tyrosine 3-Monooxygenase

1990
Synthesis and pharmacology of the enantiomers of cis-7-hydroxy-3-methyl-2-(dipropylamino)tetralin.
    Journal of medicinal chemistry, 1990, Volume: 33, Issue:10

    Topics: 5-Hydroxytryptophan; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Apomorphine; Binding, Competitive; Cattle; Chemical Phenomena; Chemistry, Physical; Computer Simulation; Crystallography; Dihydroxyphenylalanine; Dopamine Antagonists; In Vitro Techniques; Isomerism; Male; Molecular Conformation; Molecular Structure; Motor Activity; Rats; Reserpine; Spiperone; Structure-Activity Relationship; Tetrahydronaphthalenes; X-Ray Diffraction

1990
(S)-5-fluoro-8-hydroxy-2-(dipropylamino)tetralin: a putative 5-HT1A-receptor antagonist.
    Journal of medicinal chemistry, 1990, Volume: 33, Issue:6

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Brain; Chemical Phenomena; Chemistry; Dihydroxyphenylalanine; Naphthalenes; Rats; Receptors, Dopamine; Receptors, Dopamine D2; Serotonin; Serotonin Antagonists; Stereoisomerism; Tetrahydronaphthalenes

1990
Effects of 5-HT and 8-OH-DPAT on forebrain monoamine synthesis after local application into the median and dorsal raphe nuclei of the rat.
    Journal of neural transmission. General section, 1990, Volume: 81, Issue:2

    Topics: 5-Hydroxytryptophan; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Catecholamines; Dihydroxyphenylalanine; Enzyme Inhibitors; Frontal Lobe; Hydrazines; Male; Naphthalenes; Raphe Nuclei; Rats; Rats, Inbred Strains; Serotonin; Tetrahydronaphthalenes

1990
The 5-HT 1A receptor agonist, 8-OH-DPAT, preferentially activates cell body 5-HT autoreceptors in rat brain in vivo.
    Naunyn-Schmiedeberg's archives of pharmacology, 1988, Volume: 338, Issue:5

    Topics: 5-Hydroxytryptophan; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Brain; Brain Chemistry; Dihydroxyphenylalanine; Dopamine; Hydroxyindoleacetic Acid; Male; Naphthalenes; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin; Tetrahydronaphthalenes

1988
Resolved N,N-dialkylated 2-amino-8-hydroxytetralins: stereoselective interactions with 5-HT1A receptors in the brain.
    Journal of medicinal chemistry, 1989, Volume: 32, Issue:4

    Topics: 5-Hydroxytryptophan; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Brain Stem; Chemical Phenomena; Chemistry; Corpus Striatum; Dihydroxyphenylalanine; Dopamine; Limbic System; Male; Motor Activity; Naphthalenes; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Serotonin; Serotonin; Stereoisomerism; Structure-Activity Relationship; Tetrahydronaphthalenes

1989
Antipsychotic-like properties of the 5-HT1A agonist 8-OH-DPAT in the rat.
    Pharmacology & toxicology, 1989, Volume: 64, Issue:1

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Avoidance Learning; Behavior, Animal; Dihydroxyphenylalanine; Ergolines; Naphthalenes; Quinpirole; Rats; Serotonin; Sexual Behavior, Animal; Tetrahydronaphthalenes

1989
Evidence for selective inhibition of limbic forebrain dopamine synthesis by 8-OH-DPAT in the rat.
    Naunyn-Schmiedeberg's archives of pharmacology, 1989, Volume: 339, Issue:5

    Topics: 5-Hydroxytryptophan; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Corpus Striatum; Depression, Chemical; Dihydroxyphenylalanine; Dopamine; Ergolines; Hydrazines; Limbic System; Male; Naphthalenes; Piperidines; Quinpirole; Rats; Rats, Inbred Strains; Reserpine; Serotonin; Tetrahydronaphthalenes; Tryptophan Hydroxylase; Tyrosine 3-Monooxygenase

1989
Effects of the C3-methylated derivatives of 8-hydroxy-2-(di-n-propylamino)tetralin (8-OH-DPAT) on central 5-hydroxytryptamine receptors.
    European journal of pharmacology, 1987, Nov-03, Volume: 143, Issue:1

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Behavior, Animal; Dihydroxyphenylalanine; Dopamine; Homovanillic Acid; Male; Motor Activity; Naphthalenes; Potassium Chloride; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin; Stereoisomerism; Tetrahydronaphthalenes; Tryptophan Hydroxylase

1987
(+)-UH 232 and (+)-UH 242: novel stereoselective dopamine receptor antagonists with preferential action on autoreceptors.
    Journal of neural transmission, 1986, Volume: 65, Issue:1

    Topics: 4-Butyrolactone; 5-Hydroxytryptophan; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Apomorphine; Behavior, Animal; Dihydroxyphenylalanine; Dopamine; Dose-Response Relationship, Drug; Drug Interactions; Male; Motor Activity; Naphthalenes; Norepinephrine; Rats; Rats, Inbred Strains; Receptors, Dopamine; Reserpine; Serotonin; Stereoisomerism; Tetrahydronaphthalenes

1986
Novel dopamine receptor agonists and antagonists with preferential action on autoreceptors.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:8

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Brain; Dihydroxyphenylalanine; Male; Motor Activity; Naphthalenes; Rats; Rats, Inbred Strains; Receptors, Dopamine; Stereoisomerism; Tetrahydronaphthalenes

1985
Derivatives of 2-(dipropylamino)tetralin: effect of the C8-substituent on the interaction with 5-HT1A receptors.
    Journal of medicinal chemistry, 1993, Dec-24, Volume: 36, Issue:26

    Topics: 5-Hydroxytryptophan; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Binding, Competitive; Body Temperature; Brain; Cerebral Cortex; Chemical Phenomena; Chemistry, Physical; Dihydroxyphenylalanine; Dopamine; Hippocampus; Hydroxyindoleacetic Acid; Male; Molecular Structure; Motor Activity; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Reserpine; Serotonin; Stereoisomerism

1993
(R)- and (S)-8-acetyl-2-(dipropylamino)tetralin (LY-41): two novel 5-HT1A receptor agonists.
    European journal of pharmacology, 1993, Jan-26, Volume: 231, Issue:1

    Topics: 5-Hydroxytryptophan; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Behavior, Animal; Body Temperature; Dihydroxyphenylalanine; Dopamine; Male; Molecular Structure; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Stereoisomerism; Tetrahydronaphthalenes

1993
Neurochemical evidence that 5-hydroxytryptaminergic neurons tonically inhibit noradrenergic neurons terminating in the hypothalamus.
    Brain research, 1993, Apr-02, Volume: 607, Issue:1-2

    Topics: 3,4-Dihydroxyphenylacetic Acid; 5-Hydroxytryptophan; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Brain Chemistry; Catecholamines; Dihydroxyphenylalanine; Dopamine; Dorsomedial Hypothalamic Nucleus; Dose-Response Relationship, Drug; Female; Hydrolysis; Hypothalamus; Male; Methoxyhydroxyphenylglycol; Neurons; Norepinephrine; Rats; Serotonin; Thalamic Nuclei

1993
The pharmacological characterization of a novel selective 5-hydroxytryptamine1A receptor antagonist, NAD-299.
    The Journal of pharmacology and experimental therapeutics, 1997, Volume: 283, Issue:1

    Topics: 5-Hydroxytryptophan; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Avoidance Learning; Benzopyrans; Body Temperature; Corticosterone; Dihydroxyphenylalanine; Male; Piperazines; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Antagonists

1997
In vivo intrinsic efficacy of the 5-HT1A receptor antagonists NAD-299, WAY-100,635 and (S)-(-)-UH-301 at rat brain monoamine receptors.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 1999, Volume: 9, Issue:1-2

    Topics: 5-Hydroxytryptophan; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Benzopyrans; Brain Chemistry; Dihydroxyphenylalanine; Dose-Response Relationship, Drug; Enzyme Inhibitors; Hippocampus; Hydrazines; Male; Neostriatum; Piperazines; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Biogenic Amine; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Antagonists

1999
An endogenous serotonergic rhythm acting on 5-HT(2A) receptors may be involved in the diurnal changes in tuberoinfundibular dopaminergic neuronal activity and prolactin secretion in female rats.
    Neuroendocrinology, 2000, Volume: 72, Issue:1

    Topics: 3,4-Dihydroxyphenylacetic Acid; 5,7-Dihydroxytryptamine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Circadian Rhythm; Dihydroxyphenylalanine; Dopamine; Estrogens; Female; Ketanserin; Nerve Degeneration; Neurons; Ovariectomy; Pituitary Gland; Prolactin; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Serotonin; Serotonin Agents; Serotonin Antagonists; Serotonin Receptor Agonists

2000
Non-serotonergic potentiation by (-)-pindolol of DOI-induced forward locomotion in rats: possible involvement of beta-adrenoceptors?.
    Journal of neural transmission (Vienna, Austria : 1996), 2000, Volume: 107, Issue:8-9

    Topics: 5-Hydroxytryptophan; 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic beta-Antagonists; Adrenergic Uptake Inhibitors; Animals; Betaxolol; Biogenic Monoamines; Dihydroxyphenylalanine; Drug Synergism; Indophenol; Male; Motor Activity; Pindolol; Piperazines; Piperidines; Propanolamines; Prosencephalon; Pyridines; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT1B; Receptors, Adrenergic, beta; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Reserpine; Serotonin Antagonists; Serotonin Receptor Agonists

2000
A9 and A10 dopamine nuclei as a site of action for effects of 8-OH-DPAT on locomotion in the rat.
    Pharmacology, biochemistry, and behavior, 2000, Volume: 67, Issue:1

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Dihydroxyphenylalanine; Male; Motor Activity; Rats; Rats, Sprague-Dawley; Serotonin Receptor Agonists; Substantia Nigra; Ventral Tegmental Area

2000
Supersensitivity of 5-HT1A autoreceptors and alpha2-adrenoceptors regulating monoamine synthesis in the brain of morphine-dependent rats.
    Naunyn-Schmiedeberg's archives of pharmacology, 2002, Volume: 365, Issue:3

    Topics: 5-Hydroxytryptophan; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Autoreceptors; Biogenic Monoamines; Brain; Dihydroxyphenylalanine; Male; Morphine; Morphine Dependence; Naloxone; Narcotics; Norepinephrine; Piperazines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Receptor Agonists; Substance Withdrawal Syndrome

2002
Withdrawal from chronic ethanol increases the sensitivity of presynaptic 5-HT(1A) receptors modulating serotonin and dopamine synthesis in rat brain in vivo.
    Neuroscience letters, 2002, Jun-28, Volume: 326, Issue:2

    Topics: 5-Hydroxytryptophan; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Brain; Buspirone; Cerebral Cortex; Chronic Disease; Corpus Striatum; Dihydroxyphenylalanine; Dopamine; Ethanol; Hippocampus; Male; Presynaptic Terminals; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin; Serotonin Receptor Agonists; Substance Withdrawal Syndrome

2002
Chronic treatment and withdrawal of the cannabinoid agonist WIN 55,212-2 modulate the sensitivity of presynaptic receptors involved in the regulation of monoamine syntheses in rat brain.
    Naunyn-Schmiedeberg's archives of pharmacology, 2009, Volume: 379, Issue:1

    Topics: 5-Hydroxytryptophan; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Autoreceptors; Benzoxazines; Biogenic Monoamines; Brain; Cannabinoid Receptor Agonists; Cerebellum; Corpus Striatum; Dihydroxyphenylalanine; Hippocampus; Male; Morpholines; Naphthalenes; Norepinephrine; Rats; Rats, Sprague-Dawley; Serotonin; Serotonin 5-HT1 Receptor Agonists; Substance Withdrawal Syndrome

2009