Compounds > 8-hydroxy-2-(di-n-propylamino)tetralin

8-hydroxy-2-(di-n-propylamino)tetralin and benzofurans

8-hydroxy-2-(di-n-propylamino)tetralin has been researched along with benzofurans in 10 studies

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (20.00)18.2507
2000's6 (60.00)29.6817
2010's2 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Huang, X; Johnson, MP; Nichols, DE; Tomaszewski, Z1
Marona-Lewicka, D; Monte, AP; Nelson, DL; Nichols, DE; Parker, MA; Wainscott, DB1
Lutz, EA; Shannon, HE1
Cryan, JF; Dalvi, A; Lucki, I; Manning, DR; Page, ME; Saucy, B; Sullivan, A1
Bartoszyk, GD; Dawson, LA; Hagan, JJ; Hill, M; Hughes, ZA; Langmead, CJ; Middlemiss, DN; Starr, KR1
Bartoszyk, GD; Hagan, JJ; Kew, JN; Roberts, C1
Bourdiol, N; Colpaert, F; Cuisiat, S; Lacharme, V; Newman-Tancredi, A; Vacher, B1
Bruins Slot, LA; Cussac, D; Grevoz-Barret, C; Lestienne, F; Newman-Tancredi, A1
Ashby, CR; Athanasiou, M; Bartoszyk, GD; Kehne, JH; Pierz, KA; Renda, MJ; Seyfried, CA1
Seyfried, CA; van Amsterdam, C1

Other Studies

10 other study(ies) available for 8-hydroxy-2-(di-n-propylamino)tetralin and benzofurans

ArticleYear
Benzofuran bioisosteres of hallucinogenic tryptamines.
    Journal of medicinal chemistry, 1992, May-29, Volume: 35, Issue:11

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Benzofurans; Ethylamines; Frontal Lobe; Hallucinogens; Hippocampus; Male; Molecular Structure; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin Antagonists; Structure-Activity Relationship; Tetrahydronaphthalenes; Tryptamines

1992
Dihydrobenzofuran analogues of hallucinogens. 3. Models of 4-substituted (2,5-dimethoxyphenyl)alkylamine derivatives with rigidified methoxy groups.
    Journal of medicinal chemistry, 1996, Jul-19, Volume: 39, Issue:15

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Behavior, Animal; Benzofurans; Binding, Competitive; Cell Membrane; Cricetinae; Hallucinogens; Hippocampus; Humans; Ketanserin; Lysergic Acid Diethylamide; Male; Mesocricetus; Molecular Conformation; Molecular Structure; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Structure-Activity Relationship; Tritium

1996
Yohimbine produces antinociception in the formalin test in rats: involvement of serotonin(1A) receptors.
    Psychopharmacology, 2000, Volume: 149, Issue:1

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic alpha-Antagonists; Animals; Benzofurans; Bridged Bicyclo Compounds, Heterocyclic; Dose-Response Relationship, Drug; Ergolines; Formaldehyde; Male; Nociceptors; Oxadiazoles; Pain; Pain Measurement; Piperazines; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1D; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Antagonists; Serotonin Receptor Agonists; Time Factors; Yohimbine

2000
Behavioral and neurochemical effects of 5-(4-[4-(5-Cyano-3-indolyl)-butyl)-butyl]-1-piperazinyl)-benzofuran-2-carboxamide (EMD 68843): a combined selective inhibitor of serotonin reuptake and 5-hydroxytryptamine(1A) receptor partial agonist.
    The Journal of pharmacology and experimental therapeutics, 2002, Volume: 302, Issue:3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antidepressive Agents, Second-Generation; Behavior, Animal; Benzofurans; Brain Chemistry; Cell Line; Extracellular Space; Female; Fluoxetine; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Indoles; Microdialysis; Piperazines; Prefrontal Cortex; Protein Binding; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Selective Serotonin Reuptake Inhibitors; Serotonin Receptor Agonists; Swimming; Vilazodone Hydrochloride

2002
Neurochemical evaluation of the novel 5-HT1A receptor partial agonist/serotonin reuptake inhibitor, vilazodone.
    European journal of pharmacology, 2005, Mar-07, Volume: 510, Issue:1-2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Benzofurans; Benzylamines; Binding, Competitive; Cell Membrane; Dopamine; Dose-Response Relationship, Drug; Extracellular Space; Frontal Lobe; Guanosine 5'-O-(3-Thiotriphosphate); Hippocampus; Indoles; Male; Microdialysis; Norepinephrine; Paroxetine; Piperazines; Piperidones; Pyridines; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin 5-HT1 Receptor Agonists; Serotonin Antagonists; Serotonin Receptor Agonists; Spiro Compounds; Sulfur Radioisotopes; Time Factors; Tritium; Vilazodone Hydrochloride

2005
Effect of vilazodone on 5-HT efflux and re-uptake in the guinea-pig dorsal raphe nucleus.
    European journal of pharmacology, 2005, Jul-04, Volume: 517, Issue:1-2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Benzofurans; Dose-Response Relationship, Drug; Fluoxetine; Guinea Pigs; In Vitro Techniques; Indoles; Male; Piperazines; Pyridines; Raphe Nuclei; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Vilazodone Hydrochloride

2005
Towards a new generation of potential antipsychotic agents combining D2 and 5-HT1A receptor activities.
    Journal of medicinal chemistry, 2007, Feb-22, Volume: 50, Issue:4

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antipsychotic Agents; Behavior, Animal; Benzofurans; Benzylamines; Dopamine D2 Receptor Antagonists; HeLa Cells; Humans; Radioligand Assay; Rats; Serotonin 5-HT1 Receptor Agonists; Signal Transduction; Stereoisomerism; Structure-Activity Relationship

2007
F15063, a potential antipsychotic with dopamine D(2)/D(3) receptor antagonist and 5-HT(1A) receptor agonist properties: influence on immediate-early gene expression in rat prefrontal cortex and striatum.
    European journal of pharmacology, 2009, Oct-12, Volume: 620, Issue:1-3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antipsychotic Agents; Benzofurans; Benzylamines; Clozapine; Cyclopentanes; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Gene Expression Regulation; Genes, Immediate-Early; Haloperidol; Male; Mitogen-Activated Protein Kinase 3; Neostriatum; Piperazines; Prefrontal Cortex; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1A; Receptors, Dopamine; Receptors, Dopamine D3; RNA, Messenger; Serotonin 5-HT1 Receptor Agonists; Serotonin Receptor Agonists; Time Factors

2009
Electrophysiological evidence for rapid 5-HT₁A autoreceptor inhibition by vilazodone, a 5-HT₁A receptor partial agonist and 5-HT reuptake inhibitor.
    European journal of pharmacology, 2013, Aug-15, Volume: 714, Issue:1-3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Benzofurans; Brain Stem; Drug Partial Agonism; Electrophysiological Phenomena; Fenfluramine; Indoles; Male; p-Chloroamphetamine; Piperazines; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1A; Selective Serotonin Reuptake Inhibitors; Serotonergic Neurons; Serotonin Receptor Agonists; Time Factors; Vilazodone Hydrochloride

2013
Mechanism of action of the bimodal antidepressant vilazodone: evidence for serotonin1A-receptor-mediated auto-augmentation of extracellular serotonin output.
    Psychopharmacology, 2014, Volume: 231, Issue:12

    Topics: 5-Hydroxytryptophan; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antidepressive Agents; Benzofurans; Brain; Citalopram; Dose-Response Relationship, Drug; Drug Interactions; Extracellular Space; Fluoxetine; Indoles; Male; Paroxetine; Piperazines; Pyridines; Rats, Wistar; Receptor, Serotonin, 5-HT1A; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin 5-HT1 Receptor Agonists; Serotonin Antagonists; Serotonin Receptor Agonists; Vilazodone Hydrochloride

2014