Compounds > 8-hydroxy-2-(di-n-propylamino)tetralin

8-hydroxy-2-(di-n-propylamino)tetralin and alpha-aminopyridine

8-hydroxy-2-(di-n-propylamino)tetralin has been researched along with alpha-aminopyridine in 54 studies

Research

Studies (54)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	17 (31.48)	18.2507
2000's	24 (44.44)	29.6817
2010's	11 (20.37)	24.3611
2020's	2 (3.70)	2.80

Authors

Authors	Studies
Burris, KD; Butkerait, P; Graham, TE; Hallak, H; Manning, DR; Miller, HA; Molinoff, PB; Zheng, Y	1
Frazer, A; Thielen, RJ	1
Frederick, D; Kung, HF; Kung, MP; Zhuang, ZP	1
Fangon, NB; Frazer, A; Thielen, RJ	1
De Lanerolle, NC; Shaikh, MB; Siegel, A	1
Leander, JD; Wolff, MC	1
Ahlemeyer, B; Krieglstein, J	1
Hull, EM; Lorrain, DS; Matuszewich, L	1
Cook, DF; Wirtshafter, D	1
Bjorvatn, B; Fornal, CA; Jacobs, BL; Martín, FJ; Metzler, CW	1
Chattopadhyay, A; Harikumar, KG	3
Koob, GF; Parsons, LH; Weiss, F	1
Dominguez, J; Hull, EM; Lorrain, DS; Matuszewich, L; Putnam, SK; Trujillo, R	1
Dekeyne, A; Girardon, S; Millan, MJ	1
Heils, A; Lesch, KP; Li, Q; Murphy, DL; Van De Kar, LD; Wichems, C	1
Assié, MB; Cosi, C; Koek, W	1
Ferreira, M; Gillis, RA; Sahibzada, N; Taveira-DaSilva, AM; Wasserman, AM	1
Bartoszyk, GD; Böttcher, H; de Boer, P; Greiner, HE; Harting, J; Liao, Y; Mensonides-Harsema, MM; Wikström, HV	1
Chen, CA; Manning, DR	1
Aerts, J; Brihaye, C; Comar, D; Degueldre, C; Le Bars, D; Lemaire, C; Luxen, A; Plenevaux, A; Pujol, J; Weissmann, D	1
Chattopadhyay, A; Harikumar, KG; John, PT	1
Moerschbaecher, JM; Winsauer, PJ	1
Harrison, AA; Markou, A	1
Bjorvatn, B; Grønli, J; Sørensen, E; Ursin, R	1
Assié, MB; Colpaert, FC; Cosi, C; Koek, W; Patoiseau, JF; Pauwels, PJ; Vacher, B	1
Amstislavskaya, TG; Popova, NK	1
Carr, IC; Milligan, G; Welsby, PJ; Wilkinson, G	1
Bingaman, M; Gillis, RA; Pace, PP; Taveira-DaSilva, AM; Teng, YD; Wrathall, JR	1
Bhatt, S; Hassanain, M; Siegel, A	1
Billinton, A; Duxon, MS; Quinn, LP; Stean, TO; Stratton, SC; Trail, B; Upton, N	1
Chattopadhyay, A; Harikumar, KG; Kalipatnapu, S; Karnik, SS; Pucadyil, TJ; Rangaraj, N	1
Chattopadhyay, A; Harikumar, KG; Kalipatnapu, S; Pucadyil, TJ	1
Gallardo-Ortíz, IA; López-Guerrero, JJ; Orozco-Méndez, M; Villalobos-Molina, R	1
Chattopadhyay, A; Jafurulla, M; Pucadyil, TJ	1
Defraiteur, C; Goblet, D; Luxen, A; Plenevaux, A; Rouchet, N; Scuvée-Moreau, J; Seutin, V	1
Gajendiran, M	1
de Arruda Camargo, GM; de Arruda Camargo, LA; de Souza Villa, P; Menani, JV; Saad, WA	1
Assié, MB; Bruins Slot, L; Buritova, J; Colpaert, FC; Cosi, C; Cussac, D; Heusler, P; Lauressergues, E; Martel, JC; Newman-Tancredi, A; Vacher, B	1
Kondaurova, EM; Naumenko, VS; Popova, NK	1
Amat, J; Christianson, JP; Fleshner, M; Greenwood, BN; Maier, SF; Paul, ED; Ragole, T; Strong, PV; Watkins, LR	1
France, CP; Koek, W; Li, JX; Rice, KC	1
Bai, YJ; Cao, JX; Cui, SY; Cui, XY; Wang, LE; Zhang, J; Zhang, QY; Zhang, YH; Zhao, YY	1
Auclair, AL; Bardin, L; Colpaert, FC; Depoortère, R; Newman-Tancredi, A; Vacher, B	1
Che, CT; Huang, Z; Ip, SP; Mao, QQ; Xian, YF	1
Wang, LE; Yin, YQ; Zhang, XQ; Zhang, YH	1
Amini, E; Jonaidi, H; Taati, M; Zendehdel, M	1
Babapour, V; Baghbanzadeh, A; Hassanpour, S; Mokhtarpouriani, K; Pourrahimi, M; Zendehdel, M	1
Burnett, EJ; Davenport, AT; Friedman, DP; Grant, KA; Hemby, SE	1
Browne, CJ; Fletcher, PJ; Higgins, GA; Soko, AD; Zeeb, FD	1
Baptista-de-Souza, D; Canto-de-Souza, A; Canto-de-Souza, L; Nunes-de-Souza, RL; Pelarin, V	1
Corrêa, FM; Fortaleza, EA; Matthiesen, M; Mendes, LD; Spiacci, A; Zangrossi, H	1
Broadbear, JH; Depoortere, RY; Newman-Tancredi, A; Ralph, D; Tunstall, BJ; Vacy, K	1

Other Studies

54 other study(ies) available for 8-hydroxy-2-(di-n-propylamino)tetralin and alpha-aminopyridine

Article	Year
Expression of the human 5-hydroxytryptamine1A receptor in Sf9 cells. Reconstitution of a coupled phenotype by co-expression of mammalian G protein subunits. The Journal of biological chemistry, 1995, Aug-04, Volume: 270, Issue:31 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amino Acid Sequence; Aminopyridines; Animals; Baculoviridae; Base Sequence; Cell Line; GTP-Binding Proteins; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Humans; Molecular Sequence Data; Peptide Fragments; Piperazines; Protein Processing, Post-Translational; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Recombinant Proteins; Signal Transduction; Spodoptera	1995
Effects of novel 5-HT1A receptor antagonists on measures of post-synaptic 5-HT1A receptor activation in vivo. Life sciences, 1995, Volume: 56, Issue:7 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aminopyridines; Animals; Body Temperature; Male; Piperazines; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Serotonin Antagonists	1995
In vivo binding of [123I]4-(2'-methoxyphenyl)-1-[2'-(N-2"-pyridinyl)- p-iodobenzamido-]ethyl-piperazine, p-MPPI, to 5-HT1A receptors in rat brain. Synapse (New York, N.Y.), 1994, Volume: 18, Issue:4 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aminopyridines; Animals; Autoradiography; Brain; Iodine Radioisotopes; Isotope Labeling; Ligands; Male; Piperazines; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Serotonin Antagonists; Tissue Distribution	1994
4-(2'-Methoxyphenyl)-1-[2'-[N-(2"-pyridinyl)-p-iodobenzamido]ethyl] piperazine and 4-(2'-methoxyphenyl)-1-[2'-[N-(2"-pyridinyl)-p- fluorobenzamido]ethyl]piperazine, two new antagonists at pre- and postsynaptic serotonin-1A receptors. The Journal of pharmacology and experimental therapeutics, 1996, Volume: 277, Issue:2 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aminopyridines; Animals; Autoreceptors; Body Temperature; Brain Chemistry; Dose-Response Relationship, Drug; Guanylyl Imidodiphosphate; Hydroxyindoleacetic Acid; Male; Piperazines; Posture; Rats; Rats, Sprague-Dawley; Serotonin; Serotonin Antagonists	1996
Serotonin 5-HT1A and 5-HT2/1C receptors in the midbrain periaqueductal gray differentially modulate defensive rage behavior elicited from the medial hypothalamus of the cat. Brain research, 1997, Aug-15, Volume: 765, Issue:2 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aminopyridines; Animals; Behavior, Animal; Cats; Female; Hypothalamus; Immunohistochemistry; Male; Mesencephalon; Periaqueductal Gray; Piperazines; Receptors, Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists	1997
Differentiation of 5-HT1A receptor ligands by drug discrimination. European journal of pharmacology, 1997, Aug-27, Volume: 333, Issue:2-3 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Aminopyridines; Animals; Behavior, Animal; Buspirone; Columbidae; Cyclohexylamines; Discrimination Learning; Dose-Response Relationship, Drug; Idazoxan; Ligands; Male; Pindolol; Piperazines; Pyridines; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Antagonists; Serotonin Receptor Agonists	1997
Stimulation of 5-HT1A receptor inhibits apoptosis induced by serum deprivation in cultured neurons from chick embryo. Brain research, 1997, Nov-28, Volume: 777, Issue:1-2 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic beta-Antagonists; Aminopyridines; Animals; Apoptosis; Cells, Cultured; Chick Embryo; Chlorpromazine; Culture Media, Serum-Free; Dopamine Antagonists; Nerve Growth Factors; Neurons; Neuroprotective Agents; Piperazines; Propranolol; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Antagonists; Serotonin Receptor Agonists; Telencephalon	1997
8-OH-DPAT influences extracellular levels of serotonin and dopamine in the medial preoptic area of male rats. Brain research, 1998, Apr-20, Volume: 790, Issue:1-2 Topics: 5,7-Dihydroxytryptamine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Aminopyridines; Animals; Carrier Proteins; Dopamine; Extracellular Space; Male; Membrane Glycoproteins; Membrane Transport Proteins; Microdialysis; Microinjections; Nerve Tissue Proteins; Piperazines; Preoptic Area; Rats; Rats, Inbred Strains; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin; Serotonin Agents; Serotonin Antagonists; Serotonin Plasma Membrane Transport Proteins; Serotonin Receptor Agonists; Sexual Behavior, Animal	1998
Serotonin-1B agonists induce compartmentally organized striatal Fos expression in rats. Neuroreport, 1998, Apr-20, Volume: 9, Issue:6 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aminopyridines; Animals; Corpus Striatum; Immunohistochemistry; Indoles; Male; Nerve Tissue Proteins; Piperazines; Piperidines; Proto-Oncogene Proteins c-fos; Pyridines; Rats; Rats, Sprague-Dawley; Serotonin Antagonists; Serotonin Receptor Agonists	1998
The 5-HT1A receptor antagonist p-MPPI blocks 5-HT1A autoreceptors and increases dorsal raphe unit activity in awake cats. European journal of pharmacology, 1998, Sep-04, Volume: 356, Issue:2-3 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Action Potentials; Aminopyridines; Animals; Autoreceptors; Cats; Drug Interactions; Electroencephalography; Electrophysiology; Male; Motor Activity; Piperazines; Raphe Nuclei; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Antagonists; Serotonin Receptor Agonists; Wakefulness	1998
Modulation of agonist and antagonist interactions in serotonin 1A receptors by alcohols. FEBS letters, 1998, Oct-30, Volume: 438, Issue:1-2 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Alcohols; Aminopyridines; Animals; Binding Sites; Buffers; Butanols; Cattle; Cell Membrane; Dose-Response Relationship, Drug; Ethanol; Hexanols; Hippocampus; Ligands; Octanols; Piperazines; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Antagonists; Serotonin Receptor Agonists; Solubility	1998
Serotonin1B receptor stimulation enhances cocaine reinforcement. The Journal of neuroscience : the official journal of the Society for Neuroscience, 1998, Dec-01, Volume: 18, Issue:23 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aminopyridines; Animals; Cocaine; Cocaine-Related Disorders; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Indoles; Injections, Intraventricular; Male; Oxadiazoles; Piperazines; Pyridines; Pyrroles; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT1B; Receptors, Serotonin; Self Administration; Serotonin Antagonists; Serotonin Receptor Agonists	1998
Partial antagonism of 8-OH-DPAT'S effects on male rat sexual behavior with a D2, but not a 5-HT1A, antagonist. Brain research, 1999, Feb-27, Volume: 820, Issue:1-2 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aminopyridines; Animals; Copulation; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Ejaculation; Male; Piperazines; Preoptic Area; Raclopride; Rats; Rats, Long-Evans; Reaction Time; Salicylamides; Serotonin Antagonists; Sexual Behavior, Animal	1999
Discriminative stimulus properties of the novel serotonin (5-HT)2C receptor agonist, RO 60-0175: a pharmacological analysis. Neuropharmacology, 1999, Volume: 38, Issue:3 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aminopyridines; Animals; Conditioning, Operant; Ethylamines; Fluorobenzenes; Indoles; Male; Mianserin; Piperazines; Piperidines; Pyrazines; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; Reinforcement, Psychology; Serotonin Antagonists; Serotonin Receptor Agonists; Thiophenes	1999
Differential discrimination of G-protein coupling of serotonin(1A) receptors from bovine hippocampus by an agonist and an antagonist. FEBS letters, 1999, Sep-03, Volume: 457, Issue:3 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aminopyridines; Animals; Cattle; Cell Membrane; GTP-Binding Proteins; Guanine Nucleotides; Guanosine 5'-O-(3-Thiotriphosphate); Hippocampus; In Vitro Techniques; Piperazines; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Antagonists; Serotonin Receptor Agonists; Signal Transduction	1999
Reduction of 5-hydroxytryptamine (5-HT)(1A)-mediated temperature and neuroendocrine responses and 5-HT(1A) binding sites in 5-HT transporter knockout mice. The Journal of pharmacology and experimental therapeutics, 1999, Volume: 291, Issue:3 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenocorticotropic Hormone; Aminopyridines; Animals; Autoradiography; Body Temperature; Carrier Proteins; Corticosterone; Dose-Response Relationship, Drug; Hypothalamus; Membrane Glycoproteins; Membrane Transport Proteins; Mice; Mice, Knockout; Nerve Tissue Proteins; Neurosecretory Systems; Oxytocin; Piperazines; Pyridines; Raphe Nuclei; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin; Serotonin Antagonists; Serotonin Plasma Membrane Transport Proteins; Serotonin Receptor Agonists; Time Factors	1999
Correlation between low/high affinity ratios for 5-HT(1A) receptors and intrinsic activity. European journal of pharmacology, 1999, Dec-10, Volume: 386, Issue:1 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aminopyridines; Animals; Colforsin; GTP-Binding Protein alpha Subunits, Gi-Go; Guanylyl Imidodiphosphate; HeLa Cells; Hippocampus; Humans; In Vitro Techniques; Male; Membranes; Pertussis Toxin; Piperazines; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Antagonists; Serotonin Receptor Agonists; Virulence Factors, Bordetella	1999
Reversal of morphine-induced apnea in the anesthetized rat by drugs that activate 5-hydroxytryptamine(1A) receptors. The Journal of pharmacology and experimental therapeutics, 2000, Volume: 292, Issue:2 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aminopyridines; Animals; Apnea; Buspirone; Diaphragm; Drug Interactions; Electromyography; Male; Morphine; Muscle Contraction; Piperazines; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists	2000
Synthesis and in vitro and in vivo functional studies of ortho-substituted phenylpiperazine and N-substituted 4-N-(o-methoxyphenyl)aminopiperidine analogues of WAY100635. Journal of medicinal chemistry, 2000, Feb-10, Volume: 43, Issue:3 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aminopyridines; Animals; Frontal Lobe; Guinea Pigs; Hypothermia; Ileum; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; Piperazines; Pyridines; Radioligand Assay; Rats; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Antagonists; Serotonin Receptor Agonists; Structure-Activity Relationship; Ultrasonics; Vocalization, Animal	2000
Regulation of galpha i palmitoylation by activation of the 5-hydroxytryptamine-1A receptor. The Journal of biological chemistry, 2000, Aug-04, Volume: 275, Issue:31 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aminopyridines; Animals; CHO Cells; Cricetinae; GTP-Binding Protein alpha Subunits, Gi-Go; GTP-Binding Protein alpha Subunits, Gs; Humans; Palmitic Acid; Piperazines; Protein Processing, Post-Translational; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Signal Transduction; Virulence Factors, Bordetella	2000
Tissue distribution, autoradiography, and metabolism of 4-(2'-methoxyphenyl)-1-[2' -[N-2"-pyridinyl)-p-[(18)F]fluorobenzamido]ethyl]piperazine (p-[(18)F]MPPF), a new serotonin 5-HT(1A) antagonist for positron emission tomography: An In vivo study in rats. Journal of neurochemistry, 2000, Volume: 75, Issue:2 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aminopyridines; Animals; Autoradiography; Binding Sites; Brain; Fluorine Radioisotopes; Male; Organ Specificity; Piperazines; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Regression Analysis; Serotonin Antagonists; Tissue Distribution; Tomography, Emission-Computed; Tritium	2000
Role of disulfides and sulfhydryl groups in agonist and antagonist binding in serotonin1A receptors from bovine hippocampus. Cellular and molecular neurobiology, 2000, Volume: 20, Issue:6 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aminopyridines; Animals; Binding Sites; Cattle; Cell Membrane; Dithiothreitol; Ethylmaleimide; Guanosine 5'-O-(3-Thiotriphosphate); Hippocampus; Kinetics; Ligands; Piperazines; Radioligand Assay; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Antagonists; Serotonin Receptor Agonists; Tritium	2000
Differential effects of 5-HT agonists and antagonists on the repeated acquisition and performance of response sequences in monkeys. Behavioural pharmacology, 2000, Volume: 11, Issue:7-8 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aminopyridines; Amphetamines; Animals; Behavior, Animal; Dose-Response Relationship, Drug; Ergolines; Learning; Macaca fascicularis; Macaca mulatta; Piperazines; Pyridines; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Ritanserin; Serotonin Antagonists; Serotonin Receptor Agonists	2000
Serotonergic manipulations both potentiate and reduce brain stimulation reward in rats: involvement of serotonin-1A receptors. The Journal of pharmacology and experimental therapeutics, 2001, Volume: 297, Issue:1 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aminopyridines; Animals; Brain; Dose-Response Relationship, Drug; Fluoxetine; Male; Piperazines; Raphe Nuclei; Rats; Rats, Wistar; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Reward; Serotonin Antagonists; Serotonin Receptor Agonists	2001
The selective 5-HT(1A) receptor antagonist p-MPPI antagonizes sleep--waking and behavioural effects of 8-OH-DPAT in rats. Behavioural brain research, 2001, Volume: 121, Issue:1-2 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aminopyridines; Animals; Arousal; Dose-Response Relationship, Drug; Injections, Intraperitoneal; Injections, Subcutaneous; Male; Piperazines; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Antagonists; Sleep Stages; Wakefulness	2001
5-HT1A receptor activation and antidepressant-like effects: F 13714 has high efficacy and marked antidepressant potential. European journal of pharmacology, 2001, May-25, Volume: 420, Issue:2-3 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aminopyridines; Animals; Antidepressive Agents; Binding, Competitive; Buspirone; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Guanosine 5'-O-(3-Thiotriphosphate); HeLa Cells; Humans; Male; Motor Activity; Piperazines; Piperidines; Pyridines; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Antagonists; Serotonin Receptor Agonists; Swimming	2001
Modulation of antagonist binding to serotonin1A receptors from bovine hippocampus by metal ions. Cellular and molecular neurobiology, 2001, Volume: 21, Issue:5 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aminopyridines; Animals; Cations; Cattle; Cell Membrane; Hippocampus; Kinetics; Ligands; Magnesium; Manganese; Metals; Piperazines; Potassium; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Antagonists; Sodium	2001
Involvement of the 5-HT(1A) and 5-HT(1B) serotonergic receptor subtypes in sexual arousal in male mice. Psychoneuroendocrinology, 2002, Volume: 27, Issue:5 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aminopyridines; Animals; Female; Male; Mice; Mice, Inbred BALB C; Mice, Inbred CBA; Motivation; Piperazines; Quinoxalines; Receptor, Serotonin, 5-HT1B; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Antagonists; Serotonin Receptor Agonists; Sexual Behavior, Animal	2002
Regulation of the avidity of ternary complexes containing the human 5-HT(1A) receptor by mutation of a receptor contact site on the interacting G protein alpha subunit. British journal of pharmacology, 2002, Volume: 137, Issue:3 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adenylyl Cyclases; Aminopyridines; Cell Line; Glycine; Guanosine Diphosphate; Heterotrimeric GTP-Binding Proteins; Humans; Isoleucine; Ligands; Mutation; Piperazines; Radioligand Assay; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Recombinant Fusion Proteins; Serotonin Receptor Agonists; Suramin	2002
Serotonin 1A receptor agonists reverse respiratory abnormalities in spinal cord-injured rats. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2003, May-15, Volume: 23, Issue:10 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aminopyridines; Animals; Buspirone; Female; Piperazines; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Respiration; Respiratory Function Tests; Respiratory System Abnormalities; Serotonin Antagonists; Serotonin Receptor Agonists; Spinal Cord Injuries; Wounds, Nonpenetrating	2003
Differential modulation of feline defensive rage behavior in the medial hypothalamus by 5-HT1A and 5-HT2 receptors. Brain research, 2003, Aug-15, Volume: 981, Issue:1-2 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aggression; Aminopyridines; Animals; Behavior, Animal; Cats; Dose-Response Relationship, Drug; Electric Stimulation; Female; Hypothalamus, Middle; Indophenol; Periaqueductal Gray; Piperazines; Predatory Behavior; Rage; Reaction Time; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Agents; Serotonin Antagonists; Time Factors	2003
LABORAS: Initial pharmacological validation of a system allowing continuous monitoring of laboratory rodent behaviour. Journal of neuroscience methods, 2003, Nov-30, Volume: 130, Issue:1 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aminopyridines; Amphetamine; Angiotensin II; Animals; Antipsychotic Agents; Behavior, Animal; Central Nervous System Stimulants; Feeding Behavior; Haloperidol; Indoles; Injections, Intraventricular; Male; Motor Activity; Piperazines; Psychology, Experimental; Psychotropic Drugs; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1A; Receptor, Serotonin, 5-HT2C; Serotonin Antagonists; Serotonin Receptor Agonists	2003
G-protein-dependent cell surface dynamics of the human serotonin1A receptor tagged to yellow fluorescent protein. Biochemistry, 2004, Dec-21, Volume: 43, Issue:50 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aluminum Compounds; Aminopyridines; Animals; Bacterial Proteins; Binding, Competitive; Cell Membrane; CHO Cells; Cricetinae; Cricetulus; Fluorescence Recovery After Photobleaching; Fluorides; Heterotrimeric GTP-Binding Proteins; Humans; Ligands; Luminescent Proteins; Piperazines; Radioligand Assay; Receptor, Serotonin, 5-HT1A; Transfection	2004
Ligand binding characteristics of the human serotonin1A receptor heterologously expressed in CHO cells. Bioscience reports, 2004, Volume: 24, Issue:2 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aminopyridines; Animals; Binding Sites; Binding, Competitive; Cell Membrane; CHO Cells; Clone Cells; Cricetinae; Cricetulus; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Kinetics; Ligands; Piperazines; Radioligand Assay; Receptor, Serotonin, 5-HT1A; Sensitivity and Specificity; Serotonin Antagonists; Serotonin Receptor Agonists; Transfection; Tritium	2004
WAY 405, a new silent 5-HT (1A) receptor antagonist with low affinity for vascular alpha (1)-adrenoceptors. Autonomic & autacoid pharmacology, 2005, Volume: 25, Issue:4 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aminopyridines; Animals; Aorta; Blood Pressure; Dose-Response Relationship, Drug; Drug Interactions; Heart Rate; In Vitro Techniques; Male; Norepinephrine; Piperazines; Rabbits; Rats; Receptors, Adrenergic, alpha-1; Serotonin 5-HT1 Receptor Antagonists; Serotonin Antagonists; Serotonin Receptor Agonists; Tail; Vasoconstrictor Agents	2005
Prolonged treatment with ligands affects ligand binding to the human serotonin(1A) receptor in Chinese hamster ovary cells. Cellular and molecular neurobiology, 2006, Volume: 26, Issue:3 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aminopyridines; Animals; Cell Membrane; CHO Cells; Cricetinae; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Ligands; Piperazines; Receptor, Serotonin, 5-HT1A; Serotonin 5-HT1 Receptor Agonists; Serotonin 5-HT1 Receptor Antagonists; Serotonin Receptor Agonists	2006
Characterization of 4-(2-hydroxyphenyl)-1-[2'-[N-(2''-pyridinyl)-p-fluorobenzamido]ethyl]piperazine (p-DMPPF) as a new potent 5-HT1A antagonist. British journal of pharmacology, 2007, Volume: 152, Issue:6 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aminopyridines; Animals; Benzamides; Binding, Competitive; Electrophysiology; In Vitro Techniques; Kinetics; Male; Neurons; Piperazines; Protein Binding; Pyridines; Radioligand Assay; Raphe Nuclei; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT1A; Serotonin Antagonists; Serotonin Receptor Agonists	2007
In vivo evidence for serotonin 5-HT2C receptor-mediated long-lasting excitability of lumbar spinal reflex and its functional interaction with 5-HT1A receptor in the mammalian spinal cord. Brain research bulletin, 2008, Mar-28, Volume: 75, Issue:5 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aminopyridines; Amphetamines; Animals; Drug Interactions; Electric Stimulation; Indoles; Lumbosacral Region; Male; Membrane Potentials; Motor Neurons; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT1A; Receptor, Serotonin, 5-HT2C; Reflex, Monosynaptic; Serotonin Antagonists; Serotonin Receptor Agonists; Spinal Cord	2008
Activation of the serotonergic 5-HT1A receptor in the paraventricular nucleus of the hypothalamus inhibits water intake and increases urinary excretion in water-deprived rats. Regulatory peptides, 2008, Oct-09, Volume: 150, Issue:1-3 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aminopyridines; Animals; Diuresis; Dose-Response Relationship, Drug; Drinking; Drug Interactions; Male; Paraventricular Hypothalamic Nucleus; Piperazines; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1A; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Time Factors; Water Deprivation	2008
Signal transduction and functional selectivity of F15599, a preferential post-synaptic 5-HT1A receptor agonist. British journal of pharmacology, 2009, Volume: 156, Issue:2 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aminopyridines; Animals; Autoradiography; Binding, Competitive; CHO Cells; Cricetinae; Cricetulus; Extracellular Signal-Regulated MAP Kinases; In Vitro Techniques; Male; Phosphorylation; Piperidines; Prefrontal Cortex; Proto-Oncogene Proteins c-fos; Pyridines; Pyrimidines; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1A; Serotonin 5-HT1 Receptor Agonists; Signal Transduction	2009
Central 5-HT3 receptor-induced hypothermia in mice: interstrain differences and comparison with hypothermia mediated via 5-HT1A receptor. Neuroscience letters, 2009, Nov-06, Volume: 465, Issue:1 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aminopyridines; Animals; Biguanides; Blood-Brain Barrier; Body Temperature; Dose-Response Relationship, Drug; Hypothermia; Male; Mice; Mice, Inbred Strains; Ondansetron; Piperazines; Receptor, Serotonin, 5-HT1A; Receptors, Serotonin, 5-HT3; Serotonin 5-HT1 Receptor Antagonists; Serotonin 5-HT3 Receptor Agonists; Serotonin Antagonists; Serotonin Receptor Agonists; Species Specificity	2009
5-hydroxytryptamine 2C receptors in the basolateral amygdala are involved in the expression of anxiety after uncontrollable traumatic stress. Biological psychiatry, 2010, Feb-15, Volume: 67, Issue:4 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aminopyridines; Amygdala; Analysis of Variance; Animals; Animals, Newborn; Anxiety; Disease Models, Animal; Electroshock; Indoles; Microdialysis; Rats; Receptor, Serotonin, 5-HT2C; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Social Behavior; Stress Disorders, Traumatic	2010
Differential effects of serotonin 5-HT1A receptor agonists on the discriminative stimulus effects of the 5-HT2A receptor agonist 1-(2,5-dimethoxy-4-methylphenyl)-2-aminopropane in rats and rhesus monkeys. The Journal of pharmacology and experimental therapeutics, 2010, Volume: 333, Issue:1 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aminopyridines; Animals; Discrimination, Psychological; DOM 2,5-Dimethoxy-4-Methylamphetamine; Drug Interactions; Macaca mulatta; Male; Phenethylamines; Piperidines; Rats; Rats, Sprague-Dawley; Serotonin 5-HT1 Receptor Agonists; Serotonin 5-HT2 Receptor Agonists; Tryptamines	2010
Potentiating effect of spinosin, a C-glycoside flavonoid of Semen Ziziphi spinosae, on pentobarbital-induced sleep may be related to postsynaptic 5-HT(1A) receptors. Phytomedicine : international journal of phytotherapy and phytopharmacology, 2010, Volume: 17, Issue:6 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aminopyridines; Animals; Drug Synergism; Drug Therapy, Combination; Drugs, Chinese Herbal; Flavonoids; Glycosides; Male; Monosaccharides; Pentobarbital; Phytotherapy; Piperazines; Rats; Rats, Sprague-Dawley; Seeds; Serotonin; Serotonin 5-HT1 Receptor Antagonists; Sleep; Sleep Initiation and Maintenance Disorders; Sleep, REM; Time Factors; Wakefulness; Ziziphus	2010
F15599, a preferential post-synaptic 5-HT1A receptor agonist: activity in models of cognition in comparison with reference 5-HT1A receptor agonists. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2010, Volume: 20, Issue:9 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aminopyridines; Animals; Cognition; Disease Models, Animal; Enzyme Inhibitors; Male; Memory, Short-Term; Phencyclidine; Piperidines; Pyrimidines; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1A; Reflex, Startle; Serotonin 5-HT1 Receptor Agonists; Signal Transduction	2010
Role of 5-HT(1A) and 5-HT(1B) receptors in the antidepressant-like effect of piperine in the forced swim test. Neuroscience letters, 2011, Oct-24, Volume: 504, Issue:2 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Alkaloids; Aminopyridines; Animals; Antidepressive Agents; Benzodioxoles; Data Interpretation, Statistical; Male; Methiothepin; Mice; Mice, Inbred ICR; Motor Activity; Piperazines; Piperidines; Polyunsaturated Alkamides; Propanolamines; Pyridines; Receptor, Serotonin, 5-HT1A; Receptor, Serotonin, 5-HT1B; Serotonin 5-HT1 Receptor Agonists; Serotonin 5-HT1 Receptor Antagonists; Swimming	2011
Augmentative effect of spinosin on pentobarbital-induced loss of righting reflex in mice associated with presynaptic 5-HT1A receptor. The Journal of pharmacy and pharmacology, 2012, Volume: 64, Issue:2 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Administration, Oral; Aminopyridines; Analysis of Variance; Animals; Drugs, Chinese Herbal; Flavonoids; Hypothermia; Male; Mice; Mice, Inbred ICR; Pentobarbital; Piperazines; Receptor, Serotonin, 5-HT1A; Receptors, Presynaptic; Reflex, Righting; Serotonin Receptor Agonists	2012
The role of central 5-HT(2C) and NMDA receptors on LPS-induced feeding behavior in chickens. The journal of physiological sciences : JPS, 2012, Volume: 62, Issue:5 Topics: 2-Amino-5-phosphonovalerate; 8-Hydroxy-2-(di-n-propylamino)tetralin; Aminopyridines; Animals; Anorexia; Chickens; Feeding Behavior; Indoles; Lipopolysaccharides; Receptor, Serotonin, 5-HT2C; Receptors, N-Methyl-D-Aspartate; Serotonin 5-HT1 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists	2012
The effect of serotonergic system on nociceptin/orphanin FQ induced food intake in chicken. The journal of physiological sciences : JPS, 2013, Volume: 63, Issue:4 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aminopyridines; Animals; Chickens; Feeding Behavior; Fenclonine; Fluoxetine; Indoles; Injections, Intraventricular; Male; Nociceptin; Opioid Peptides; Receptor, Serotonin, 5-HT2C; Serotonin; Serotonin 5-HT2 Receptor Antagonists; Serotonin Antagonists	2013
The effects of chronic ethanol self-administration on hippocampal 5-HT1A receptors in monkeys. Drug and alcohol dependence, 2014, Mar-01, Volume: 136 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Alcoholism; Aminopyridines; Animals; Autoradiography; Central Nervous System Depressants; DNA, Complementary; Ethanol; Gene Expression; Hippocampus; Housing, Animal; Macaca fascicularis; Male; Piperazines; Polymerase Chain Reaction; Receptor, Serotonin, 5-HT1A; Receptors, G-Protein-Coupled; RNA; Self Administration; Serotonin Antagonists; Serotonin Receptor Agonists	2014
Effects of 5-HT Psychopharmacology, 2017, Volume: 234, Issue:5 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aminopyridines; Amphetamines; Animals; Conditioning, Operant; Fluorobenzenes; Indoles; Male; Methylphenidate; Piperazines; Piperidines; Pyridines; Rats; Receptor, Serotonin, 5-HT1A; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2C; Reinforcement, Psychology; Serotonin 5-HT1 Receptor Agonists; Serotonin 5-HT1 Receptor Antagonists; Serotonin 5-HT2 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists; Serotonin Antagonists; Serotonin Receptor Agonists	2017
Interplay between 5-HT Neuropharmacology, 2018, 09-15, Volume: 140 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aminopyridines; Animals; Dose-Response Relationship, Drug; Drug Interactions; Fear; Indoles; Male; Mice; Microinjections; Nociception; Pain Measurement; Periaqueductal Gray; Pyrazines; Receptor, Serotonin, 5-HT1A; Receptor, Serotonin, 5-HT2C; Serotonin 5-HT2 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists	2018
Serotonin 2C receptors in the basolateral amygdala mediate the anxiogenic effect caused by serotonergic activation of the dorsal raphe dorsomedial subnucleus. Journal of psychopharmacology (Oxford, England), 2020, Volume: 34, Issue:4 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aminopyridines; Animals; Anxiety; Basolateral Nuclear Complex; Dorsal Raphe Nucleus; Electric Stimulation; Indoles; Kainic Acid; Male; Piperazines; Pyridines; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT2C; Serotonergic Neurons; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists	2020
Discriminative stimulus properties of the 5-HT1A receptor biased agonists NLX-101 and F13714, in rats trained to discriminate 8-OH-DPAT from saline. Behavioural pharmacology, 2021, 12-01, Volume: 32, Issue:8 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aminopyridines; Animals; Buspirone; Discrimination Learning; Dose-Response Relationship, Drug; Female; Male; Piperazines; Piperidines; Pyridines; Pyrimidines; Rats; Rats, Sprague-Dawley; Serotonin 5-HT1 Receptor Agonists	2021