8-hydroxy-2-(di-n-propylamino)tetralin has been researched along with 6-chloro-2-(1-piperazinyl)pyrazine in 29 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (37.93) | 18.7374 |
| 1990's | 9 (31.03) | 18.2507 |
| 2000's | 6 (20.69) | 29.6817 |
| 2010's | 3 (10.34) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Baldy, WJ; Davis, CB; DiStefano, DL; Elgin, RJ; Fedde, CL; Kesslick, JM; Martin, GE; Mathiasen, JR; Scott, MK; Shank, RP | 1 |
| Audia, JE; Baez, M; Cohen, ML; Kursar, JD; Lucaites, VL; Nelson, DL; Nissen, JS; Schenck, KW; Wainscott, DB | 1 |
| Benwell, K; Bickerdike, M; Kennett, G; Knight, AR; Misra, A; Quirk, K; Revell, D | 1 |
| Berendsen, HH; Broekkamp, CL | 4 |
| Bethea, CL; Lorens, SA; Urban, JH; Van de Kar, LD | 1 |
| Gudelsky, GA; Meltzer, HY; Nash, JF | 2 |
| Meltzer, HY; Nash, JF | 1 |
| Barrett, JE; Bolger, GT; Mansbach, RS; Skolnick, P; Weissman, B; Witkin, JM | 1 |
| Gudelsky, GA; Koenig, JI; Meltzer, HY | 3 |
| Lorens, SA; Van de Kar, LD | 1 |
| Harris, LT; McCall, RB; Patel, BN | 1 |
| Berendsen, HH; Broekkamp, CL; Kester, RC; Peeters, BW | 1 |
| Meltzer, HY; Willins, DL | 1 |
| Ishikane, T | 1 |
| Dekeyne, A; Girardon, S; Millan, MJ | 1 |
| Batman, AM; Beardsley, PM; Munzar, P | 1 |
| Hochman, S; Machacek, DW; Sawchuk, M; Shay, BL | 1 |
| Hurley, LM | 1 |
| Abbas, AI; Arbuckle, MI; Caron, MG; Grant, SG; Roth, BL; Yadav, PN; Yao, WD | 1 |
| Gomes, KS; Nunes-De-Souza, RL | 1 |
| Mallmann, ES; Paixão, L; Ribeiro, MF; Spritzer, PM | 1 |
| Aldegunde, M; Mancebo, MJ; Otero-Rodiño, C; Pérez-Maceira, JJ; Soengas, JL | 1 |
| Baptista-de-Souza, D; Canto-de-Souza, A; Canto-de-Souza, L; Nunes-de-Souza, RL; Pelarin, V | 1 |
29 other study(ies) available for 8-hydroxy-2-(di-n-propylamino)tetralin and 6-chloro-2-(1-piperazinyl)pyrazine
| Article | Year |
|---|---|
Activity of aromatic substituted phenylpiperazines lacking affinity for dopamine binding sites in a preclinical test of antipsychotic efficacy.
Topics: Animals; Antipsychotic Agents; Avoidance Learning; Dose-Response Relationship, Drug; Piperazines; Rats; Receptors, Dopamine; Receptors, Serotonin; Structure-Activity Relationship | 1989 |
Pharmacological characteristics of the newly cloned rat 5-hydroxytryptamine2F receptor.
Topics: Animals; Binding Sites; Cell Line; Cloning, Molecular; Gastric Fundus; Inositol 1,4,5-Trisphosphate; Male; Muscle Contraction; Muscle, Smooth; Radioligand Assay; Rats; Rats, Wistar; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Temperature | 1993 |
Pharmacological characterisation of the agonist radioligand binding site of 5-HT(2A), 5-HT(2B) and 5-HT(2C) receptors.
Topics: Binding Sites; Binding, Competitive; Cell Line; Humans; Radioligand Assay; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2B; Receptor, Serotonin, 5-HT2C; Recombinant Proteins; Serotonin 5-HT2 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists; Serotonin Antagonists; Serotonin Receptor Agonists | 2004 |
Attenuation of 5-HT1A and 5-HT2 but not 5-HT1C receptor mediated behaviour in rats following chronic treatment with 5-HT receptor agonists, antagonists or anti-depressants.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Antidepressive Agents; Behavior, Animal; Bridged Bicyclo Compounds; Bridged-Ring Compounds; Male; Mianserin; Penile Erection; Pyrazines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin Antagonists; Tetrahydronaphthalenes; Tranylcypromine | 1991 |
Behavioural evidence for functional interactions between 5-HT-receptor subtypes in rats and mice.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Behavior, Animal; Body Temperature; Male; Mice; Mice, Inbred ICR; Motor Activity; Piperazines; Pyrazines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin Antagonists; Tetrahydronaphthalenes | 1990 |
Effect of selective serotonin (5-HT) agonists and 5-HT2 antagonist on prolactin secretion.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Ergolines; Fenfluramine; Indoles; Male; Prolactin; Pyrazines; Radioimmunoassay; Rats; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Tetrahydronaphthalenes | 1989 |
Selective cross-tolerance to 5-HT1A and 5-HT2 receptor-mediated temperature and corticosterone responses.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Body Temperature Regulation; Corticosterone; Dose-Response Relationship, Drug; Drug Interactions; Male; Methoxydimethyltryptamines; Naphthalenes; Pyrazines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Tetrahydronaphthalenes; Tryptamines | 1989 |
Effect of gepirone and ipsapirone on the stimulated and unstimulated secretion of prolactin in the rat.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; alpha-Methyltyrosine; Animals; Anti-Anxiety Agents; Electric Stimulation; Haloperidol; Male; Methoxydimethyltryptamines; Methyltyrosines; Prolactin; Pyrazines; Pyrimidines; Rats; Rats, Inbred Strains; Receptors, Dopamine; Tetrahydronaphthalenes | 1989 |
Behavioral studies with anxiolytic drugs. IV. Serotonergic involvement in the effects of buspirone on punished behavior of pigeons.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Anti-Anxiety Agents; Buspirone; Columbidae; Dose-Response Relationship, Drug; Ketanserin; Male; Punishment; Pyrazines; Pyrimidines; Receptors, Serotonin; Serotonin; Tetrahydronaphthalenes; Tritium | 1987 |
Antagonism of serotonin receptor mediated neuroendocrine and temperature responses by atypical neuroleptics in the rat.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antipsychotic Agents; Body Temperature; Butyrophenones; Chlorpromazine; Clozapine; Corticosterone; Haloperidol; Male; Neurosecretory Systems; Pyrazines; Pyrimidinones; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin Antagonists; Tetrahydronaphthalenes | 1988 |
Thermoregulatory responses to serotonin (5-HT) receptor stimulation in the rat. Evidence for opposing roles of 5-HT2 and 5-HT1A receptors.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Body Temperature Regulation; Ketanserin; Male; Methoxydimethyltryptamines; Pindolol; Piperidines; Pyrazines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Spiperone; Tetrahydronaphthalenes | 1986 |
Differential effects of serotonin (5-HT1A and 5-HT2) agonists and antagonists on renin and corticosterone secretion.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Corticosterone; Ergolines; Fenfluramine; Male; Pyrazines; Pyrimidines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Renin; Serotonin; Serotonin Antagonists; Tetrahydronaphthalenes | 1987 |
Stimulation of corticosterone and beta-endorphin secretion in the rat by selective 5-HT receptor subtype activation.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; beta-Endorphin; Corticosterone; Endorphins; Ketanserin; Male; Pindolol; Pyrazines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin Antagonists; Spiperone; Tetrahydronaphthalenes | 1987 |
Selective desensitization of serotonin (5-HT) receptor-mediated hyperthermia by mianserin and other 5-HT antagonists.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Body Temperature; Dose-Response Relationship, Drug; Fever; Male; Mianserin; Pyrazines; Rats; Receptors, Serotonin; Serotonin Antagonists; Tetrahydronaphthalenes | 1987 |
Effects of serotonin1 and serotonin2 receptor agonists and antagonists on blood pressure, heart rate and sympathetic nerve activity.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Blood Pressure; Cats; Heart Rate; Piperazines; Pyrazines; Receptors, Serotonin; Serotonin Antagonists; Sympathetic Nervous System; Tetrahydronaphthalenes | 1987 |
Comparison of stimulus properties of fluoxetine and 5-HT receptor agonists in a conditioned taste aversion procedure.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Analysis of Variance; Animals; Avoidance Learning; Conditioning, Classical; Fluoxetine; Male; Mice; Paroxetine; Pyrazines; Serotonin Receptor Agonists; Taste | 1994 |
Modulation of 5-HT receptor subtype-mediated behaviours by corticosterone.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Behavior, Animal; Corticosterone; Locomotion; Male; Pyrazines; Rats; Rats, Wistar; Receptors, Serotonin; Serotonin Receptor Agonists | 1996 |
Indirect in vivo 5-HT1A-agonistic effects of the new antidepressant mirtazapine.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Antidepressive Agents, Tricyclic; Behavior, Animal; Conditioning, Operant; Fluoxetine; Male; Mianserin; Mice; Mice, Inbred ICR; Mirtazapine; Pyrazines; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Selective Serotonin Reuptake Inhibitors; Serotonin Receptor Agonists; Taste | 1997 |
Serotonin 5-HT2C agonists selectively inhibit morphine-induced dopamine efflux in the nucleus accumbens.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Cocaine; Dopamine; Dopamine Uptake Inhibitors; Male; Microdialysis; Morphine; Narcotic Antagonists; Nucleus Accumbens; Piperazines; Pyrazines; Rats; Rats, Sprague-Dawley; Serotonin Antagonists; Serotonin Receptor Agonists | 1998 |
[Effects of serotonergic drugs on the up-regulation of dopamine D2 receptors induced by haloperidol in rat striatum].
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Anti-Dyskinesia Agents; Antipsychotic Agents; Citalopram; Corpus Striatum; Dopamine Antagonists; Haloperidol; Male; Pyrazines; Rats; Rats, Wistar; Receptors, Dopamine D2; Ritanserin; Selective Serotonin Reuptake Inhibitors; Serotonin Receptor Agonists; Up-Regulation | 1998 |
Discriminative stimulus properties of the novel serotonin (5-HT)2C receptor agonist, RO 60-0175: a pharmacological analysis.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aminopyridines; Animals; Conditioning, Operant; Ethylamines; Fluorobenzenes; Indoles; Male; Mianserin; Piperazines; Piperidines; Pyrazines; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; Reinforcement, Psychology; Serotonin Antagonists; Serotonin Receptor Agonists; Thiophenes | 1999 |
Attenuation of nicotine's discriminative stimulus effects in rats and its locomotor activity effects in mice by serotonergic 5-HT2A/2C receptor agonists.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Conditioning, Operant; Discrimination, Psychological; Excitatory Amino Acid Antagonists; Indophenol; Ketamine; Male; Mice; Motor Activity; Nicotine; Nicotinic Agonists; Pyrazines; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2C; Serotonin Antagonists; Serotonin Receptor Agonists | 2005 |
Serotonin 5-HT2 receptors induce a long-lasting facilitation of spinal reflexes independent of ionotropic receptor activity.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Analysis of Variance; Animals; Animals, Newborn; Clozapine; Dose-Response Relationship, Radiation; Drug Interactions; Electric Stimulation; Female; Ganglia, Spinal; Immunohistochemistry; In Vitro Techniques; Male; Pyrazines; Rats; Rats, Sprague-Dawley; Reaction Time; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin, 5-HT2; Reflex; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Spinal Cord; Time Factors | 2005 |
Different serotonin receptor agonists have distinct effects on sound-evoked responses in inferior colliculus.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Acoustic Stimulation; Animals; Chiroptera; Dose-Response Relationship, Drug; Electrodes; Electrophysiology; Evoked Potentials, Auditory; Extracellular Space; gamma-Aminobutyric Acid; Glutamic Acid; Inferior Colliculi; Iontophoresis; Male; Pyrazines; Pyridines; Pyrroles; Receptor, Serotonin, 5-HT1A; Serotonin; Serotonin Receptor Agonists | 2006 |
PSD-95 is essential for hallucinogen and atypical antipsychotic drug actions at serotonin receptors.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Analysis of Variance; Animals; Animals, Newborn; Antipsychotic Agents; Cerebral Cortex; Disks Large Homolog 4 Protein; Gene Expression Regulation; Green Fluorescent Proteins; Guanylate Kinases; Hallucinogens; Hypothermia; Intracellular Signaling Peptides and Proteins; Membrane Proteins; Mice; Mice, Knockout; Microtubule-Associated Proteins; Neural Inhibition; Neurons; Protein Binding; Protein Transport; Proto-Oncogene Proteins c-fos; Pyrazines; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; RNA, Messenger; Serotonin Antagonists; Serotonin Receptor Agonists; Transduction, Genetic | 2009 |
Implication of the 5-HT2A and 5-HT2C (but not 5HT1A) receptors located within the periaqueductal gray in the elevated plus-maze test-retest paradigm in mice.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Analysis of Variance; Animals; Anxiety; Behavior, Animal; Disease Models, Animal; Dose-Response Relationship, Drug; Male; Maze Learning; Mice; Microinjections; Motor Activity; Periaqueductal Gray; Pyrazines; Receptor, Serotonin, 5-HT1A; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2C; Reproducibility of Results; Serotonin 5-HT1 Receptor Agonists; Serotonin 5-HT2 Receptor Agonists; Serotonin Agents | 2009 |
Serotonergic 5-HT2A/2C receptors are involved in prolactin secretion in hyperestrogenic rats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Estradiol; Estrogens; Female; Pindolol; Prolactin; Pyrazines; Rats, Wistar; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2C; Serotonin Antagonists; Serotonin Receptor Agonists | 2014 |
Food intake inhibition in rainbow trout induced by activation of serotonin 5-HT2C receptors is associated with increases in POMC, CART and CRF mRNA abundance in hypothalamus.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Agouti-Related Protein; Animals; Corticotropin-Releasing Hormone; Eating; Fish Proteins; Gene Expression; Hypothalamus; Nerve Tissue Proteins; Oncorhynchus mykiss; Pro-Opiomelanocortin; Pyrazines; Quinoxalines; Receptor, Serotonin, 5-HT1A; Receptor, Serotonin, 5-HT2C; RNA, Messenger; Serotonin Receptor Agonists | 2016 |
Interplay between 5-HT
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aminopyridines; Animals; Dose-Response Relationship, Drug; Drug Interactions; Fear; Indoles; Male; Mice; Microinjections; Nociception; Pain Measurement; Periaqueductal Gray; Pyrazines; Receptor, Serotonin, 5-HT1A; Receptor, Serotonin, 5-HT2C; Serotonin 5-HT2 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists | 2018 |