8-hydroxy-2-(di-n-propylamino)tetralin and 5-hydroxy-1-methyl-2--(di-n-propylamino)tetralin methyl ether

8-hydroxy-2-(di-n-propylamino)tetralin has been researched along with 5-hydroxy-1-methyl-2--(di-n-propylamino)tetralin methyl ether in 41 studies

Research

Studies (41)

TimeframeStudies, this research(%)All Research%
pre-19909 (21.95)18.7374
1990's26 (63.41)18.2507
2000's5 (12.20)29.6817
2010's1 (2.44)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hjorth, S; Nissbrandt, H1
Carlsson, A; Hoffmann, WE; Ljung, E; Lum, JT; Piercey, MF; Svensson, K1
Callahan, PM; Cunningham, KA; Piercey, MF1
Carlsson, A; Carlsson, M; Svensson, A1
Lum, JT; Piercey, MF1
Barber, DJ; Cooper, SJ; Rusk, IN1
Carlsson, A; Johansson, AM; Magnusson, T; Svensson, K1
Andersson, B; Arvidsson, LE; Carlsson, A; Clark, D; Hacksell, U; Hjorth, S; Johansson, AM; Sanchez, D; Svensson, K; Wikström, H1
Carlsson, A; Hajos, M; Hjorth, S; Svensson, K1
Alföldi, P; Carlsson, A; Hajós, M; Johansson, AM; Obál, F; Rubicsek, G; Svensson, K1
Carlsson, M; Clark, D; Eriksson, E; Nilsson, C; Svensson, K1
Carlsson, A; Carlsson, M; Eriksson, E; Hjorth, S; Johansson, AM; Svensson, K1
Andersson, B; Arvidsson, LE; Carlsson, A; Clark, D; Hacksell, U; Hjorth, S; Johansson, AM; Nilsson, JL; Sanchez, D; Svensson, K1
Arvidsson, LE; Carlsson, A; Johansson, AM; Nilsson, JL; Svensson, K1
Piercey, M; Roberts, DC; Smith, A1
Griffon, N; Pilon, C; Schwartz, JC; Sokoloff, P1
Aretha, CW; Galloway, MP; Sinha, A1
Caine, SB; Geyer, MA; Swerdlow, NR1
Kling-Petersen, T; Ljung, E; Svensson, K1
Gaĭnetdinov, RR; Grekhova, TV; Raevskiĭ, KS; Sotnikova, TD1
Taubes, G1
Gifford, AN; Johnson, KM1
Carlsson, A; Hansson, L; Löfberg, L; Waters, N1
Carlsson, A; Lagerkvist, S; Löfberg, L; Piercey, M; Waters, N1
Andersson, J; Hartvig, P; Inoue, O; Kanai, T; Långström, B; Lilja, A; Tani, Y; Watanabe, Y1
Andersson, J; Hartvig, P; Ishihara, T; Kanai, T; Lilija, A; Ohno, T; Onoe, H; Tani, Y; Watanabe, Y; Westerberg, G1
Kling-Petersen, T; Ljung, E; Svensson, K; Waters, N1
Emaduddin, M; Takeuchi, H1
Kleven, MS; Koek, W1
Hall, DA; Strange, PG1
Nakajima, S; Patterson, RL1
Carlsson, A; Lahti, AC; Tamminga, CA; Weiler, M1
Piercey, MF; Ray, CA; Walker, EL1
Annoh, N; Harano, M; Tanaka, M; Yamada, S1
Gainetdinov, R; Huotari, M; Männistö, PT1
Fu, D; Javitch, JA; Lin, H; Strange, PG; Wilson, J1
Gainetdinov, RR; Grekhova, TV; Rayevsky, KS; Sotnikova, TD1
Colpaert, FC; Pauwels, PJ; Tardif, S; Wurch, T1
Bisgard, GE; Herman, JK; Keith, IM; O'Halloran, KD; Wang, ZY1
Lin, H; Saisch, SG; Strange, PG1
Braszko, JJ1

Trials

1 trial(s) available for 8-hydroxy-2-(di-n-propylamino)tetralin and 5-hydroxy-1-methyl-2--(di-n-propylamino)tetralin methyl ether

ArticleYear
Effects of the D3 and autoreceptor-preferring dopamine antagonist (+)-UH232 in schizophrenia.
    Journal of neural transmission (Vienna, Austria : 1996), 1998, Volume: 105, Issue:6-7

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adult; Autoreceptors; Behavior; Dopamine Antagonists; Dose-Response Relationship, Drug; Double-Blind Method; Humans; Male; Receptors, Dopamine D2; Receptors, Dopamine D3; Schizophrenia; Schizophrenic Psychology; Stereoisomerism; Time Factors

1998

Other Studies

40 other study(ies) available for 8-hydroxy-2-(di-n-propylamino)tetralin and 5-hydroxy-1-methyl-2--(di-n-propylamino)tetralin methyl ether

ArticleYear
Dopaminergic neurotransmission in somatodendritic and terminal areas of the rat brain: susceptibility to modulation by D1 and D2 receptors and to axotomy.
    Journal of neural transmission. General section, 1992, Volume: 90, Issue:1

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; alpha-Methyltyrosine; Animals; Axons; Azepines; Brain; Corpus Striatum; Dendrites; Dopamine; Dopamine Agents; Dopamine D2 Receptor Antagonists; Male; Methyltyrosines; Nerve Endings; Pargyline; Prosencephalon; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Dopamine D2; Synaptic Transmission; Tyrosine 3-Monooxygenase

1992
Antagonism of cocaine's pharmacological effects by the stimulant dopaminergic antagonists, (+)-AJ76 and (+)-UH232.
    Brain research, 1992, Aug-21, Volume: 588, Issue:2

    Topics: 3,4-Dihydroxyphenylacetic Acid; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Behavior, Animal; Brain Chemistry; Cocaine; Dihydroxyphenylalanine; Dopamine; Dopamine Antagonists; Electrophysiology; Homovanillic Acid; Male; Microelectrodes; Motor Activity; Rats; Rats, Sprague-Dawley; Tetrahydronaphthalenes

1992
Effects of the putative dopamine autoreceptor antagonists (+)-AJ 76 and (+)-UH 232 on the discriminative stimulus properties of cocaine.
    Psychopharmacology, 1992, Volume: 107, Issue:1

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Behavior, Animal; Cocaine; Discrimination, Psychological; Dopamine Antagonists; Dose-Response Relationship, Drug; Drug Interactions; Male; Rats; Rats, Inbred Strains; Tetrahydronaphthalenes

1992
Synergistic interactions between the NMDA antagonist dizocilpine and the preferential dopamine autoreceptor antagonists (+)-AJ 76 and (+)-UH 232 with regard to locomotor stimulation in monoamine-depleted mice.
    Journal of neural transmission. General section, 1991, Volume: 85, Issue:1

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Dizocilpine Maleate; Dopamine Antagonists; Drug Synergism; Locomotion; Male; Mice; Motor Activity; N-Methylaspartate; Tetrahydronaphthalenes

1991
Electrophysiological effects of dopamine autoreceptor antagonists, (+)-AJ 76 and (+)-UH 232.
    European journal of pharmacology, 1990, Jul-03, Volume: 182, Issue:2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamine; Animals; Apomorphine; Dendrites; Dopamine; Dopamine Antagonists; Electrophysiology; Feedback; Haloperidol; In Vitro Techniques; Male; Naphthalenes; Neurons; Rats; Rats, Inbred Strains; Substantia Nigra; Tetrahydronaphthalenes

1990
Yawning induced by the selective dopamine D2 agonist N-0437 is blocked by the selective dopamine autoreceptor antagonist (+)-UH 232.
    Physiology & behavior, 1989, Volume: 45, Issue:6

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Dopamine Agents; Dopamine Antagonists; Drug Interactions; Male; Naphthalenes; Raclopride; Rats; Salicylamides; Tetrahydronaphthalenes; Thiophenes; Time Factors; Yawning

1989
(+)-AJ 76 and (+)-UH 232: central stimulants acting as preferential dopamine autoreceptor antagonists.
    Naunyn-Schmiedeberg's archives of pharmacology, 1986, Volume: 334, Issue:3

    Topics: 4-Butyrolactone; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Apomorphine; Brain; Male; Methyltyrosines; Motor Activity; Naphthalenes; Neurotransmitter Agents; Rats; Rats, Inbred Strains; Receptors, Dopamine; Reserpine; Tetrahydronaphthalenes

1986
(+)-UH 232 and (+)-UH 242: novel stereoselective dopamine receptor antagonists with preferential action on autoreceptors.
    Journal of neural transmission, 1986, Volume: 65, Issue:1

    Topics: 4-Butyrolactone; 5-Hydroxytryptophan; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Apomorphine; Behavior, Animal; Dihydroxyphenylalanine; Dopamine; Dose-Response Relationship, Drug; Drug Interactions; Male; Motor Activity; Naphthalenes; Norepinephrine; Rats; Rats, Inbred Strains; Receptors, Dopamine; Reserpine; Serotonin; Stereoisomerism; Tetrahydronaphthalenes

1986
In vivo dopamine (DA) receptor binding and behavioural effects of the putative DA autoreceptor antagonists (+)-AJ 76 and (+)-UH 232 in rats with a unilateral nigral 6-OH-DA lesion.
    Experimental brain research, 1988, Volume: 70, Issue:3

    Topics: 3,4-Dihydroxyphenylacetic Acid; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Apomorphine; Behavior, Animal; Functional Laterality; Hydroxydopamines; Male; Naphthalenes; Oxidopamine; Rats; Rats, Inbred Strains; Receptors, Dopamine; Substantia Nigra; Tetrahydronaphthalenes

1988
Dopamine autoreceptor antagonists: effects on sleep-wake activity in the rat.
    Pharmacology, biochemistry, and behavior, 1987, Volume: 26, Issue:1

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Electroencephalography; Male; Motor Activity; Naphthalenes; Rats; Receptors, Dopamine; Sleep; Tetrahydronaphthalenes

1987
Compounds with selectivity for dopamine autoreceptors: effects on prolactin secretion in male and female rats.
    Clinical neuropharmacology, 1986, Volume: 9 Suppl 4

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Azepines; Female; Male; Phenanthrenes; Piperidines; Prolactin; Rats; Rats, Inbred Strains; Receptors, Dopamine; Tetrahydronaphthalenes

1986
The putatively selective dopamine autoreceptor antagonists (+)-AJ 76 and (+)-UH 232 stimulate prolactin release in rats.
    European journal of pharmacology, 1986, Nov-04, Volume: 130, Issue:3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Azepines; Male; Naphthalenes; Prolactin; Radioimmunoassay; Rats; Rats, Inbred Strains; Receptors, Dopamine; Reserpine; Tetrahydronaphthalenes

1986
Novel dopamine receptor agonists and antagonists with preferential action on autoreceptors.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:8

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Brain; Dihydroxyphenylalanine; Male; Motor Activity; Naphthalenes; Rats; Rats, Inbred Strains; Receptors, Dopamine; Stereoisomerism; Tetrahydronaphthalenes

1985
A homologous series of N-alkylated cis-(+)-(1 S, 2 R)-5-methoxy-1-methyl-2-aminotetralins: central dopamine receptor antagonists showing profiles ranging from classical antagonism to selectivity for autoreceptors.
    Journal of neural transmission, 1986, Volume: 65, Issue:1

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Corpus Striatum; Dopamine; Drug Interactions; Male; Motor Activity; Naphthalenes; Rats; Rats, Inbred Strains; Receptors, Dopamine; Tetrahydronaphthalenes

1986
Effect of (-)-DS 121 and (+)-UH 232 on cocaine self-administration in rats.
    Psychopharmacology, 1995, Volume: 120, Issue:1

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Cocaine; Conditioning, Operant; Dopamine Antagonists; Dose-Response Relationship, Drug; Male; Nitriles; Piperidines; Rats; Rats, Inbred Strains; Self Administration

1995
The preferential dopamine D3 receptor ligand, (+)-UH232, is a partial agonist.
    European journal of pharmacology, 1995, Aug-25, Volume: 282, Issue:1-3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Ergolines; Humans; Hybrid Cells; Mitogens; Quinpirole; Receptors, Dopamine; Receptors, Dopamine D2; Receptors, Dopamine D3; Recombinant Proteins

1995
Dopamine D3-preferring ligands act at synthesis modulating autoreceptors.
    The Journal of pharmacology and experimental therapeutics, 1995, Volume: 274, Issue:2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Autoreceptors; Dopamine; Ligands; Male; Rats; Rats, Sprague-Dawley; Receptors, Dopamine; Receptors, Dopamine D2; Receptors, Dopamine D3; Tetrahydronaphthalenes

1995
Effects of D3/D2 dopamine receptor agonists and antagonists on prepulse inhibition of acoustic startle in the rat.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 1995, Volume: 12, Issue:2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Acoustic Stimulation; Animals; Apomorphine; Dopamine Agonists; Dopamine Antagonists; Dose-Response Relationship, Drug; Haloperidol; Humans; Male; Rats; Rats, Sprague-Dawley; Receptors, Dopamine; Receptors, Dopamine D2; Receptors, Dopamine D3; Reflex, Startle; Schizophrenia; Tetrahydronaphthalenes

1995
The preferential dopamine autoreceptor antagonist (+)-UH232 antagonizes the positive reinforcing effects of cocaine and d-amphetamine in the ICSS paradigm.
    Pharmacology, biochemistry, and behavior, 1994, Volume: 49, Issue:2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Brain; Cocaine; Dextroamphetamine; Dopamine Antagonists; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Electrodes; Haloperidol; Male; Piperazines; Rats; Rats, Sprague-Dawley; Reinforcement, Psychology; Self Stimulation

1994
[Regulation of liberation and metabolism of dopamine in the dorsal striatum of free-living rats: the role of D2- and D3-dopamine autoreceptors].
    Doklady Akademii nauk, 1994, Volume: 337, Issue:6

    Topics: 3,4-Dihydroxyphenylacetic Acid; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Corpus Striatum; Dopamine; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Homovanillic Acid; Microdialysis; Rats; Receptors, Dopamine; Receptors, Dopamine D2; Receptors, Dopamine D3; Tetrahydronaphthalenes

1994
Will new dopamine receptors offer a key to schizophrenia?
    Science (New York, N.Y.), 1994, Aug-19, Volume: 265, Issue:5175

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Brain; Clozapine; Dopamine Antagonists; Humans; Receptors, Dopamine; Receptors, Dopamine D2; Receptors, Dopamine D3; Receptors, Dopamine D4; Schizophrenia

1994
A pharmacological analysis of the effects of (+)-AJ 76 and (+)-UH 232 at release regulating pre- and postsynaptic dopamine receptors.
    European journal of pharmacology, 1993, Jun-24, Volume: 237, Issue:2-3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antipsychotic Agents; Binding, Competitive; Corpus Striatum; Dopamine; Dopamine Agents; Dopamine Antagonists; Ergolines; Female; In Vitro Techniques; Quinpirole; Rats; Rats, Sprague-Dawley; Receptors, Dopamine; Tetrahydronaphthalenes

1993
Intracerebral infusion of (+)-AJ76 and (+)-UH232: effects on dopamine release and metabolism in vivo.
    European journal of pharmacology, 1994, Jan-14, Volume: 251, Issue:2-3

    Topics: 3,4-Dihydroxyphenylacetic Acid; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Brain; Corpus Striatum; Dialysis; Dopamine; Dopamine Antagonists; Drug Administration Routes; Homovanillic Acid; Male; Nucleus Accumbens; Raclopride; Rats; Rats, Sprague-Dawley; Salicylamides; Tetrahydronaphthalenes

1994
The dopamine D3 receptor and autoreceptor preferring antagonists (+)-AJ76 and (+)-UH232; a microdialysis study.
    European journal of pharmacology, 1993, Sep-28, Volume: 242, Issue:2

    Topics: 3,4-Dihydroxyphenylacetic Acid; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Autoreceptors; Corpus Striatum; Dopamine; Dopamine Antagonists; Haloperidol; Male; Microdialysis; Neurons; Nucleus Accumbens; Raclopride; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; Receptors, Dopamine D3; Salicylamides; Substantia Nigra; Tetrahydronaphthalenes; Ventral Tegmental Area

1993
Positron emission tomography studies on some neurotransmitter receptor systems with 6R-tetrahydrobiopterin pretreatment.
    Advances in experimental medicine and biology, 1993, Volume: 338

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Benzazepines; Benztropine; Biopterins; Brain; Carbon Radioisotopes; Dopamine Antagonists; Glucose; Macaca mulatta; Nicotine; Receptors, Cholinergic; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, Dopamine D3; Receptors, Neurotransmitter; Regional Blood Flow; Spiperone; Tomography, Emission-Computed

1993
Positron emission tomography (PET) study: the effects of 6R-L-erythro-5,6,7,8-tetrahydrobiopterin (R-THBP, SUN 0588) on the central dopamine D1, D2 and D3 receptors in rhesus monkey.
    Advances in experimental medicine and biology, 1993, Volume: 338

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Benzazepines; Biopterins; Brain; Carbon Radioisotopes; Corpus Striatum; Dopamine Antagonists; Frontal Lobe; Kinetics; Macaca mulatta; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D2; Receptors, Dopamine D3; Spiperone; Tomography, Emission-Computed

1993
Effects on locomotor activity after local application of (+)-UH232 in discrete areas of the rat brain.
    Journal of neural transmission (Vienna, Austria : 1996), 1996, Volume: 103, Issue:3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Brain; Cortical Spreading Depression; Dopamine Antagonists; Dose-Response Relationship, Drug; Habituation, Psychophysiologic; Injections, Intraventricular; Male; Microinjections; Motor Activity; Nucleus Accumbens; Raclopride; Rats; Rats, Sprague-Dawley; Salicylamides; Ventral Tegmental Area

1996
Lineweaver-Burk analysis for the blocking effects of mammalian dopamine receptor antagonists on dopamine-induced currents in Achatina giant neurones.
    General pharmacology, 1996, Volume: 27, Issue:7

    Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Dopamine; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Ganglia, Invertebrate; In Vitro Techniques; Membrane Potentials; Neurons; Patch-Clamp Techniques; Receptors, Dopamine; Receptors, Dopamine D1; Snails; Sulpiride

1996
Dopamine D2 receptors play a role in the (-)-apomorphine-like discriminative stimulus effects of (+)-PD 128907.
    European journal of pharmacology, 1997, Feb-19, Volume: 321, Issue:1

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Apomorphine; Benzopyrans; Conditioning, Operant; Discrimination, Psychological; Dopamine Agonists; Dopamine Antagonists; Haloperidol; Male; Oxazines; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2

1997
Evidence that antipsychotic drugs are inverse agonists at D2 dopamine receptors.
    British journal of pharmacology, 1997, Volume: 121, Issue:4

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antipsychotic Agents; Butaclamol; CHO Cells; Colforsin; Cricetinae; Cyclic AMP; Dopamine Agonists; Receptors, Dopamine D2

1997
The involvement of dopamine D2 receptors, but not D3 or D4 receptors, in the rewarding effect of brain stimulation in the rat.
    Brain research, 1997, Jun-20, Volume: 760, Issue:1-2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Clozapine; Dopamine Antagonists; Dose-Response Relationship, Drug; Haloperidol; Male; Nucleus Accumbens; Raclopride; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; Receptors, Dopamine D3; Receptors, Dopamine D4; Reward; Salicylamides; Self Stimulation

1997
The effects of (+)-UH232 and (-)-DS121 on local cerebral glucose utilization in rats.
    Journal of neural transmission (Vienna, Austria : 1996), 1999, Volume: 106, Issue:1

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamine; Animals; Autoradiography; Brain; Central Nervous System Stimulants; Dopamine Antagonists; Drug Combinations; Glucose; Male; Nitriles; Piperidines; Rats; Rats, Sprague-Dawley

1999
Dopamine D(3) receptors modulate evoked dopamine release from slices of rat nucleus accumbens via muscarinic receptors, but not from the striatum.
    The Journal of pharmacology and experimental therapeutics, 1999, Volume: 291, Issue:3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Dopamine; Dopamine Agonists; Dopamine Antagonists; Electric Stimulation; Haloperidol; In Vitro Techniques; Indans; Male; Muscarinic Antagonists; Neostriatum; Nucleus Accumbens; Pirenzepine; Quinpirole; Rats; Rats, Wistar; Receptors, Dopamine D2; Receptors, Dopamine D3; Receptors, Muscarinic

1999
Microdialysis studies on the action of tolcapone on pharmacologically-elevated extracellular dopamine levels in conscious rats.
    Pharmacology & toxicology, 1999, Volume: 85, Issue:5

    Topics: 3,4-Dihydroxyphenylacetic Acid; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Benzophenones; Carbidopa; Catechol O-Methyltransferase; Dopamine; Dopamine Antagonists; Dopamine Uptake Inhibitors; Drug Interactions; Enzyme Inhibitors; Extracellular Space; Haloperidol; Homovanillic Acid; Levodopa; Male; Microdialysis; Nitrophenols; Piperazines; Rats; Rats, Wistar; Time Factors; Tolcapone; Visual Cortex

1999
Mechanisms of inverse agonism of antipsychotic drugs at the D(2) dopamine receptor: use of a mutant D(2) dopamine receptor that adopts the activated conformation.
    Journal of neurochemistry, 2001, Volume: 77, Issue:2

    Topics: 1-Methyl-3-isobutylxanthine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antipsychotic Agents; Apomorphine; Binding, Competitive; Bromocriptine; Butaclamol; Chlorpromazine; CHO Cells; Clozapine; Colforsin; Cricetinae; Cricetulus; Cyclic AMP; Dopamine Agonists; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Dose-Response Relationship, Drug; GTP-Binding Proteins; Haloperidol; Humans; Macromolecular Substances; Mutagenesis, Site-Directed; Phenethylamines; Piperidines; Protein Binding; Protein Conformation; Radioligand Assay; Receptors, Dopamine D2; Recombinant Fusion Proteins; Sodium; Spiperone; Structure-Activity Relationship; Sulpiride; Transfection; Tyramine

2001
Effects of intrastriatal infusion of D2 and D3 dopamine receptor preferring antagonists on dopamine release in rat dorsal striatum (in vivo microdialysis study).
    Pharmacological research, 2001, Volume: 43, Issue:3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Clozapine; Corpus Striatum; Dopamine; Dopamine Agonists; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Haloperidol; Male; Microdialysis; Rats; Rats, Wistar; Receptors, Dopamine D3; Spiperone; Tetrahydronaphthalenes

2001
Real-time analysis of dopamine: antagonist interactions at recombinant human D2long receptor upon modulation of its activation state.
    British journal of pharmacology, 2001, Volume: 134, Issue:1

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Alternative Splicing; Animals; Binding, Competitive; Butaclamol; Calcium; CHO Cells; Clozapine; Cricetinae; Dopamine; Dopamine Antagonists; Dose-Response Relationship, Drug; Genotype; Guanosine 5'-O-(3-Thiotriphosphate); Haloperidol; Humans; Lisuride; Mutation; Plasmids; Receptors, Dopamine; Receptors, Dopamine D2; Recombinant Proteins; Sulfur Radioisotopes; Time Factors

2001
Pharmacological and immunochemical evidence of the dopamine D3 receptor in the goat carotid body.
    Advances in experimental medicine and biology, 2001, Volume: 499

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Carotid Body; Dopamine; Dopamine Agonists; Dopamine Antagonists; Female; Goats; Nerve Fibers; Receptors, Dopamine D2; Receptors, Dopamine D3; Tetrahydronaphthalenes

2001
Assays for enhanced activity of low efficacy partial agonists at the D(2) dopamine receptor.
    British journal of pharmacology, 2006, Volume: 149, Issue:3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; CHO Cells; Cricetinae; Dopamine Agonists; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Meglumine; Receptors, Dopamine D2; Sodium

2006
(+)-UH 232, a partial agonist of the D3 dopamine receptors, attenuates cognitive effects of angiotensin IV and des-Phe(6)-angiotensin IV in rats.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2010, Volume: 20, Issue:4

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Apomorphine; Avoidance Learning; Cognition; Dopamine Antagonists; Dose-Response Relationship, Drug; Drug Interactions; Drug Partial Agonism; Exploratory Behavior; Male; Maze Learning; Rats; Receptors, Angiotensin; Receptors, Dopamine D3; Recognition, Psychology; Stereotyped Behavior

2010