Compounds > 8-hydroxy-2-(di-n-propylamino)tetralin

8-hydroxy-2-(di-n-propylamino)tetralin and 5-carboxamidotryptamine

8-hydroxy-2-(di-n-propylamino)tetralin has been researched along with 5-carboxamidotryptamine in 106 studies

Research

Studies (106)

TimeframeStudies, this research(%)All Research%
pre-19909 (8.49)18.7374
1990's65 (61.32)18.2507
2000's30 (28.30)29.6817
2010's2 (1.89)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Newman-Tancredi, A; Strange, PG; Wootton, R1
Glennon, RA2
Bull, D; den Daas, I; Foord, S; Goodson, S; Kilpatrick, G; Lee, M; Rees, S1
Adham, N; Bard, JA; Branchek, TA; Vaysse, P; Weinshank, RL; Zgombick, J1
Adham, N; Bard, J; Branchek, TA; Durkin, M; Hartig, PR; Kao, HT; Olsen, M; Schecter, LE; Urquhart, D; Weinshank, RL1
Hamblin, MW; Jose, PA; Metcalf, MA; Monsma, FJ; Shen, Y; Sibley, DR1
Amlaiky, N; Hen, R; Plassat, JL1
Arrang, JM; Diaz, J; Leurs, R; Ruat, M; Schwartz, JC; Tardivel-Lacombe, J; Traiffort, E1
Amlaiky, N; Boschert, U; Grailhe, R; Hen, R; Mattei, MG; Matthes, H; Muscatelli, F; Plassat, JL1
Audia, JE; Baez, M; Cohen, ML; Kursar, JD; Lucaites, VL; Nelson, DL; Nissen, JS; Schenck, KW; Wainscott, DB1
Carrupt, PA; Gaillard, P; Schambel, P; Testa, B1
Gommeren, W; Haegeman, G; Heylen, L; Lesage, AS; Leysen, JE; Luyten, WH; Schotte, A; Van de Weyer, I; Van Gompel, P; Vanhoenacker, P; Wouters, R1
Chang, DJ; Eglen, RM; Jasper, JR; Kosaka, A; To, ZP1
Chaput, C; Millan, MJ; Newman-Tancredi, A; Verrièle, L1
Brown, AM; Collin, LL; Ellis, CE; Forbes, IT; Gittins, SA; Gloger, I; Hagan, J; Middlemiss, DN; Riley, G; Thomas, DR1
Audinot, V; Chaput, C; Conte, C; Gavaudan, S; Millan, MJ; Newman-Tancredi, A; Touzard, M; Verrièle, L1
Giannella, M; Leonardi, A; Marucci, G; Melchiorre, C; Piergentili, A; Pigini, M; Poggesi, E; Quaglia, W1
Bolognesi, ML; Budriesi, R; Cavalli, A; Chiarini, A; Gotti, R; Leonardi, A; Melchiorre, C; Minarini, A; Poggesi, E; Recanatini, M; Rosini, M; Tumiatti, V1
Grabtree, GW; Grailhe, R; Hen, R1
Bach, T; Krobert, KA; Kvingedal, AM; Levy, FO; Syversveen, T1
Berardi, F; Colabufo, NA; Lacivita, E; Leopoldo, M; Perrone, R; Tortorella, V1
Bai, F; Johnstone, EM; Little, SP; Nelson, DL; Su, C; Varga, G; Yin, T1
Benwell, K; Bickerdike, M; Kennett, G; Knight, AR; Misra, A; Quirk, K; Revell, D1
Berardi, F; Colabufo, NA; Contino, M; Lacivita, E; Leopoldo, M; Niso, M; Perrone, R; Tortorella, V1
Berardi, F; Colabufo, NA; Contino, M; Lacivita, E; Leopoldo, M; Perrone, R1
Berardi, F; Caccia, S; Colabufo, NA; Contino, M; De Giorgio, P; Fracasso, C; Guzzetti, S; Lacivita, E; Leopoldo, M; Perrone, R1
Amantini, C; Carrieri, A; Del Bello, F; Farande, Y; Giannella, M; Leonardi, A; Lucciarini, R; Piergentili, A; Pigini, M; Poggesi, E; Quaglia, W; Rafaiani, G; Santoni, G1
Benhamú, B; Berkels, R; Lauterbach, T; López-Rodríguez, ML; Marco, I; Martín-Fontecha, M; Ramos, JA; Valhondo, M; Vázquez-Villa, H1
Dzoljic, MR; Saxena, PR; Ukponmwan, OE1
Beckett, SR; Lawrence, AJ; Marsden, CA; Marshall, PW1
Gillette, MU; Medanic, M1
Bockaert, J; Varrault, A1
Buzzi, MG; Byun, B; Moskowitz, MA; Peroutka, SJ1
Feniuk, W; Saxena, PR; Tadipatri, S; van Heuven-Nolsen, D1
Cloëz, I; Fillion, G; Harel-Dupas, C1
Simansky, KJ1
Fone, KC; Marsden, CA; Robinson, AJ1
Bach, A; Laurie, DJ; Seeburg, PH; Voigt, MM1
Laubie, M; Mennecier, P; Verbeuren, TJ1
Hoyer, D; Schoeffter, P1
Bobker, DH; Williams, JT2
Connor, HE; Higgins, GA1
Cherqui, C; Dabire, H; Schmitt, H1
Adler-Graschinsky, E; Butta, NV; Elgoyhen, AB1
Lovick, TA1
Devivo, M; Maayani, S1
Green, JP; Maayani, S; Shenker, A; Weinstein, H1
Feuerstein, TJ; Hertting, G; Lupp, A1
Gilbert, MJ; Newberry, NR1
Galligan, JJ; North, RA; Surprenant, A; Tonini, M1
Alhaider, AA; Wilcox, GL1
Miyamoto, A; Nishio, A; Sakota, T1
Buchheit, KH; Buhl, T1
Ali, Z; Barasi, S; Kozlov, A; Wu, G1
Rusak, B; Ying, SW1
Sillar, KT; Wedderburn, JF1
Pan, ZZ; Wessendorf, MW; Williams, JT1
Atger, F; Barone, P; Fillion, G; Jordan, D; Kopp, N1
Bill, DJ; Bill, SJ; Cliffe, IA; Dover, GM; Fletcher, A; Forster, EA; Haskins, JT; Jones, D; Mansell, HL; Reilly, Y1
Arneklo-Nobin, B; Bodelsson, M; Törnebrandt, K1
Holden-Dye, L; Jacques, PA; Smith, SW; Tembe, EA; Walker, RJ1
Carter, D; Champney, M; Eglen, RM; Hwang, B1
Chiba, S; Fujiwara, T1
Bobirnac, I; Schoeffter, P1
Crick, H; Manuel, NA; Wallis, DI1
Frölich, D; Göthert, M; Likungu, J; Molderings, GJ1
Gutierrez, M; Lübbert, H; Schoeffter, P; Ullmer, C; Weitz-Schmidt, G1
Cortés, R; Hurt, SD; Mengod, G; Palacios, JM; Raurich, A1
Cervera, LS; Corbitt, J; Hensler, JG; Miller, HA1
Castillo, MJ; Castro, ME; del Arco, C; del Olmo, E; Pazos, A; Romón, T1
Grünschlag, CR; Haas, HL; Stevens, DR1
Draguhn, A; Empson, RM; Gloveli, T; Heinemann, U; Schmitz, D1
Gannon, RL; Rea, MA; Weber, ET1
Pearce, WJ; Purdy, R; Teng, GQ; Williams, J; Zhang, L1
De Leyn, P; Demedts, MG; Deneffe, G; Dupont, LJ; Pype, JL; Verleden, GM1
Noma, T; Sugimoto, Y; Yamada, J; Yoshikawa, T1
Barnes, NM; Stowe, RL1
Grailhe, R; Hen, R; Moskowitz, MA; Waeber, C; Yu, XJ1
Fletcher, PJ; Korth, KM1
Bard, JA; Branchek, T; Edvinsson, L; Longmore, J; Nilsson, T; Pantev, E; Shaw, D1
Arnold, PB; Cardenas, CG; Cardenas, LM; Mar, LP; Scroggs, RS; Surmeier, DJ; Vysokanov, AV1
Bult, H; Geerts, IS; Herman, AG; Matthys, KE1
Eison, AS; Gianutsos, G; Mullins, UL1
Carr, KD; Hiller, JM; Li, H; Meller, E1
Coupar, IM; Hemedah, M; Mitchelson, FJ1
Allen, L; Hagan, JJ; Langmead, CJ; Middlemiss, DN; Price, GW; Roberts, C1
Garraway, SM; Hochman, S1
Bonaventure, P; Carruthers, N; Chai, W; Hen, R; Kwok, A; Langlois, X; Lovenberg, TW; Nepomuceno, D; Stark, K1
Awe, SO; Harris, LC; LeDay, AM; Ohia, SE; Opere, CA; Sharif, NA1
Ajubita, M; Hedo, G; Lopez-Garcia, JA1
Jørgensen, H; Kjaer, A; Knigge, U; Riis, M; Warberg, J1
Bonaventure, P; Hedlund, PB; Hein, L; Lovenberg, T; Nepomuceno, D; Sutcliffe, JG1
Duncan, MJ; Grear, KE; Hoskins, MA1
Abu-Amara, M; Aldairy, C; Hagan, JJ; Siddiqui, A; Wilson, C1
Bernhard, M; Bobirnac, I; Dev, KK; Feuerbach, D; Keser, C; Loetscher, E; Mahé, C; Schoeffter, P1
Cowen, DS; Johnson-Farley, NN; Travkina, T1
Bobirnac, I; Dev, KK; Loetscher, E; Mahé, C; Otten, U; Schoeffter, P1
Calama, E; Martín, ML; Morán, A; Ortíz de Urbina, AV; San Román, L1
Adrien, J; Boni, C; Bonnavion, P; Golmard, JL; Jacquin, TD; Leonard, G; Lesch, KP; Loucif, AJ; Macri, B; Melfort, M1
Shaharyar, S; Siddiqui, A1
García, M; Martín, ML; Morán, A; Ortizde Urbina, AV; San Román, L1
Fox, MA; French, HT; Huang, SJ; Jensen, CL; Murphy, DL; Stein, AR; Tolliver, TJ1
Jordan, D; Oskutyte, D; Ramage, AG1
Hadley, JK; Halliwell, JV1

Reviews

2 review(s) available for 8-hydroxy-2-(di-n-propylamino)tetralin and 5-carboxamidotryptamine

ArticleYear
Central serotonin receptors as targets for drug research.
    Journal of medicinal chemistry, 1987, Volume: 30, Issue:1

    Topics: Animals; Humans; Receptors, Serotonin; Research Design; Serotonin

1987
Higher-end serotonin receptors: 5-HT(5), 5-HT(6), and 5-HT(7).
    Journal of medicinal chemistry, 2003, Jul-03, Volume: 46, Issue:14

    Topics: Animals; Humans; Ligands; Receptors, Serotonin; Serotonin Agents; Serotonin Antagonists; Serotonin Receptor Agonists

2003

Trials

1 trial(s) available for 8-hydroxy-2-(di-n-propylamino)tetralin and 5-carboxamidotryptamine

ArticleYear
Autoradiographic analysis of 5-HT receptor subtypes labeled by [3H]5-CT ([3H]5-carboxamidotryptamine).
    Behavioural brain research, 1996, Volume: 73, Issue:1-2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Autoradiography; Brain; Brain Chemistry; Female; Guinea Pigs; Humans; Male; Middle Aged; Radioligand Assay; Rats; Rats, Wistar; Receptors, Serotonin; Serotonin; Serotonin Receptor Agonists; Species Specificity

1996

Other Studies

103 other study(ies) available for 8-hydroxy-2-(di-n-propylamino)tetralin and 5-carboxamidotryptamine

ArticleYear
High-level stable expression of recombinant 5-HT1A 5-hydroxytryptamine receptors in Chinese hamster ovary cells.
    The Biochemical journal, 1992, Aug-01, Volume: 285 ( Pt 3)

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adenylyl Cyclases; Animals; Binding, Competitive; Blotting, Northern; Cattle; Cell Membrane; CHO Cells; Colforsin; Cricetinae; Gene Expression; Guanosine Triphosphate; Hippocampus; Humans; Receptors, Serotonin; Recombinant Proteins; Tetrahydronaphthalenes; Transfection

1992
Cloning and characterisation of the human 5-HT5A serotonin receptor.
    FEBS letters, 1994, Dec-05, Volume: 355, Issue:3

    Topics: Amino Acid Sequence; Animals; Base Sequence; Brain Chemistry; Cloning, Molecular; Genome, Human; GTP-Binding Proteins; Humans; Mice; Molecular Sequence Data; Radioligand Assay; Receptors, Serotonin; Sequence Analysis, DNA; Sequence Homology, Amino Acid; Sequence Homology, Nucleic Acid; Serotonin; Tissue Distribution; Transfection

1994
Cloning of a novel human serotonin receptor (5-HT7) positively linked to adenylate cyclase.
    The Journal of biological chemistry, 1993, Nov-05, Volume: 268, Issue:31

    Topics: Adenylyl Cyclases; Base Sequence; Cloning, Molecular; DNA Primers; Humans; Molecular Sequence Data; Receptors, Serotonin; Sequence Alignment; Sequence Homology, Amino Acid; Serotonin Antagonists; Serotonin Receptor Agonists; Signal Transduction

1993
Cloning of another human serotonin receptor (5-HT1F): a fifth 5-HT1 receptor subtype coupled to the inhibition of adenylate cyclase.
    Proceedings of the National Academy of Sciences of the United States of America, 1993, Jan-15, Volume: 90, Issue:2

    Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Amino Acid Sequence; Animals; Base Sequence; Brain Chemistry; Cloning, Molecular; Colforsin; Dose-Response Relationship, Drug; Gene Library; Guinea Pigs; Humans; Indoles; Lymphocytes; Molecular Sequence Data; Receptors, Serotonin; RNA, Messenger; Sequence Homology, Amino Acid; Serotonin; Serotonin Receptor Agonists; Spiperone; Sulfonamides; Sumatriptan; Tissue Distribution

1993
Molecular cloning and expression of a 5-hydroxytryptamine7 serotonin receptor subtype.
    The Journal of biological chemistry, 1993, Aug-25, Volume: 268, Issue:24

    Topics: Amino Acid Sequence; Animals; Base Sequence; Binding, Competitive; Cell Line; Cell Membrane; Cloning, Molecular; Cyclic AMP; Gene Expression; Kidney Tubules, Proximal; Lysergic Acid Diethylamide; Molecular Sequence Data; Oligodeoxyribonucleotides; Polymerase Chain Reaction; Radioligand Assay; Rats; Receptors, Serotonin; Recombinant Proteins; Serotonin; Transfection

1993
Molecular cloning of a mammalian serotonin receptor that activates adenylate cyclase.
    Molecular pharmacology, 1993, Volume: 44, Issue:2

    Topics: Adenylyl Cyclases; Amino Acid Sequence; Animals; Base Sequence; Brain; Cloning, Molecular; Cyclic AMP; DNA; Drosophila; Enzyme Activation; Humans; Intestinal Mucosa; Mice; Molecular Sequence Data; Myocardium; Receptors, Serotonin; Sequence Homology, Amino Acid; Serotonin Antagonists; Serotonin Receptor Agonists

1993
Molecular cloning, characterization, and localization of a high-affinity serotonin receptor (5-HT7) activating cAMP formation.
    Proceedings of the National Academy of Sciences of the United States of America, 1993, Sep-15, Volume: 90, Issue:18

    Topics: Amino Acid Sequence; Animals; Base Sequence; Blotting, Northern; Brain; CHO Cells; Cricetinae; Cyclic AMP; DNA; Genomic Library; Kinetics; Lysergic Acid Diethylamide; Mianserin; Molecular Sequence Data; Multigene Family; Oligodeoxyribonucleotides; Organ Specificity; Rats; Receptors, Serotonin; Restriction Mapping; Serotonin; Serotonin Receptor Agonists; Transfection

1993
Mouse 5-hydroxytryptamine5A and 5-hydroxytryptamine5B receptors define a new family of serotonin receptors: cloning, functional expression, and chromosomal localization.
    Molecular pharmacology, 1993, Volume: 43, Issue:3

    Topics: Amino Acid Sequence; Animals; Base Sequence; Brain; Cell Line; Chromosome Mapping; Cloning, Molecular; DNA; Gene Expression; Humans; In Situ Hybridization; Mice; Molecular Sequence Data; Receptors, Serotonin; Serotonin Receptor Agonists

1993
Pharmacological characteristics of the newly cloned rat 5-hydroxytryptamine2F receptor.
    Molecular pharmacology, 1993, Volume: 43, Issue:3

    Topics: Animals; Binding Sites; Cell Line; Cloning, Molecular; Gastric Fundus; Inositol 1,4,5-Trisphosphate; Male; Muscle Contraction; Muscle, Smooth; Radioligand Assay; Rats; Rats, Wistar; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Temperature

1993
Binding of arylpiperazines, (aryloxy)propanolamines, and tetrahydropyridylindoles to the 5-HT1A receptor: contribution of the molecular lipophilicity potential to three-dimensional quantitative structure-affinity relationship models.
    Journal of medicinal chemistry, 1996, Jan-05, Volume: 39, Issue:1

    Topics: Indoles; Ligands; Models, Molecular; Molecular Conformation; Molecular Structure; Piperazines; Propanolamines; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin; Structure-Activity Relationship; Tetrahydronaphthalenes

1996
Alniditan, a new 5-hydroxytryptamine1D agonist and migraine-abortive agent: ligand-binding properties of human 5-hydroxytryptamine1D alpha, human 5-hydroxytryptamine1D beta, and calf 5-hydroxytryptamine1D receptors investigated with [3H]5-hydroxytryptamin
    Molecular pharmacology, 1996, Volume: 50, Issue:6

    Topics: Animals; Benzopyrans; Cattle; Cloning, Molecular; Glioma; HeLa Cells; Humans; Mice; Migraine Disorders; Propylamines; Protein Binding; Pyrimidines; Radioligand Assay; Receptors, Serotonin; Serotonin Receptor Agonists; Signal Transduction; Tritium; Tumor Cells, Cultured; Vasoconstrictor Agents

1996
Cloning, expression and pharmacology of a truncated splice variant of the human 5-HT7 receptor (h5-HT7b).
    British journal of pharmacology, 1997, Volume: 122, Issue:1

    Topics: Alternative Splicing; Amino Acid Sequence; Animals; Base Sequence; Cloning, Molecular; Cyclic AMP; DNA, Complementary; Humans; Molecular Sequence Data; Placenta; Radioligand Assay; Rats; Receptors, Serotonin; RNA, Messenger; Sequence Homology, Amino Acid; Sequence Homology, Nucleic Acid

1997
Labelling of recombinant human and native rat serotonin 5-HT1A receptors by a novel, selective radioligand, [3H]-S 15535: definition of its binding profile using agonists, antagonists and inverse agonists.
    Naunyn-Schmiedeberg's archives of pharmacology, 1998, Volume: 357, Issue:3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Affinity Labels; Animals; Binding, Competitive; CHO Cells; Cricetinae; Guanine Nucleotides; Hippocampus; Humans; Male; Membranes; Piperazines; Radiopharmaceuticals; Rats; Rats, Wistar; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Receptor Agonists

1998
Functional characterisation of the human cloned 5-HT7 receptor (long form); antagonist profile of SB-258719.
    British journal of pharmacology, 1998, Volume: 124, Issue:6

    Topics: Adenylyl Cyclases; Cell Line; Cloning, Molecular; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Piperidines; Protein Binding; Receptors, Serotonin; Recombinant Proteins; Serotonin Antagonists; Sulfonamides

1998
Agonist and antagonist actions of antipsychotic agents at 5-HT1A receptors: a [35S]GTPgammaS binding study.
    European journal of pharmacology, 1998, Aug-21, Volume: 355, Issue:2-3

    Topics: Animals; Antipsychotic Agents; CHO Cells; Cricetinae; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Agents; Sulfur Radioisotopes

1998
Structure-activity relationships in 1,4-benzodioxan-related compounds. 6. Role of the dioxane unit on selectivity for alpha(1)-adrenoreceptor subtypes.
    Journal of medicinal chemistry, 1999, Jul-29, Volume: 42, Issue:15

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Aorta, Thoracic; Cerebral Cortex; CHO Cells; Cricetinae; Dioxanes; Guinea Pigs; HeLa Cells; Humans; In Vitro Techniques; Male; Muscle, Smooth; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Receptors, Dopamine D2; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Spleen; Structure-Activity Relationship; Vas Deferens

1999
WB 4101-related compounds. 2. Role of the ethylene chain separating amine and phenoxy units on the affinity for alpha(1)-adrenoreceptor subtypes and 5-HT(1A) receptors.
    Journal of medicinal chemistry, 1999, Oct-07, Volume: 42, Issue:20

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Aorta, Thoracic; CHO Cells; Cloning, Molecular; Cricetinae; Dioxanes; HeLa Cells; Humans; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-1; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Antagonists; Serotonin Receptor Agonists; Spleen; Stereoisomerism; Structure-Activity Relationship; Vas Deferens

1999
Human 5-HT(5) receptors: the 5-HT(5A) receptor is functional but the 5-HT(5B) receptor was lost during mammalian evolution.
    European journal of pharmacology, 2001, Apr-27, Volume: 418, Issue:3

    Topics: 3T3 Cells; Amino Acid Sequence; Animals; Base Sequence; Binding, Competitive; Cell Line; COS Cells; DNA; Evolution, Molecular; Gene Expression; Genes; Humans; Membranes; Mice; Molecular Sequence Data; Phylogeny; Radioligand Assay; Receptors, Serotonin; Sequence Alignment; Sequence Analysis, DNA; Sequence Homology, Amino Acid

2001
The cloned human 5-HT7 receptor splice variants: a comparative characterization of their pharmacology, function and distribution.
    Naunyn-Schmiedeberg's archives of pharmacology, 2001, Volume: 363, Issue:6

    Topics: Adenylyl Cyclases; Alternative Splicing; Binding, Competitive; Brain; Cell Line; Cloning, Organism; Genetic Variation; Humans; Radioligand Assay; Receptors, Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Tissue Distribution

2001
Synthesis and structure-affinity relationships of 1-[omega-(4-aryl-1-piperazinyl)alkyl]-1-aryl ketones as 5-HT(7) receptor ligands.
    Journal of medicinal chemistry, 2003, Feb-13, Volume: 46, Issue:4

    Topics: Animals; Brain; Cell Line; Cricetinae; Guinea Pigs; Humans; Ileum; In Vitro Techniques; Isoxazoles; Ketones; Ligands; Liver; Muscle Contraction; Muscle, Smooth; Piperazines; Radioligand Assay; Rats; Receptors, Serotonin; Structure-Activity Relationship

2003
Molecular cloning and pharmacological characterization of the guinea pig 5-HT1E receptor.
    European journal of pharmacology, 2004, Jan-26, Volume: 484, Issue:2-3

    Topics: Amino Acid Sequence; Animals; Base Sequence; Brain; Chickens; Cloning, Molecular; Cricetinae; Dose-Response Relationship, Drug; Gerbillinae; Guinea Pigs; Haplorhini; Humans; Molecular Sequence Data; Protein Binding; Rabbits; Receptors, Serotonin; Serotonin Agents; Swine

2004
Pharmacological characterisation of the agonist radioligand binding site of 5-HT(2A), 5-HT(2B) and 5-HT(2C) receptors.
    Naunyn-Schmiedeberg's archives of pharmacology, 2004, Volume: 370, Issue:2

    Topics: Binding Sites; Binding, Competitive; Cell Line; Humans; Radioligand Assay; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2B; Receptor, Serotonin, 5-HT2C; Recombinant Proteins; Serotonin 5-HT2 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists; Serotonin Antagonists; Serotonin Receptor Agonists

2004
Structure-affinity relationship study on N-(1,2,3,4-tetrahydronaphthalen-1-yl)-4-aryl-1-piperazinealkylamides, a new class of 5-hydroxytryptamine7 receptor agents.
    Journal of medicinal chemistry, 2004, Dec-16, Volume: 47, Issue:26

    Topics: Amides; Animals; Brain; Guinea Pigs; Ileum; In Vitro Techniques; Ligands; Muscle Contraction; Muscle, Smooth; Piperazines; Radioligand Assay; Rats; Receptor, Serotonin, 5-HT1A; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Stereoisomerism; Structure-Activity Relationship; Tetrahydronaphthalenes

2004
Structure-activity relationship study on N-(1,2,3,4-tetrahydronaphthalen-1-yl)-4-aryl-1-piperazinehexanamides, a class of 5-HT7 receptor agents. 2.
    Journal of medicinal chemistry, 2007, Aug-23, Volume: 50, Issue:17

    Topics: Amides; Animals; Cell Line; Guinea Pigs; Humans; Ileum; Male; Muscle Contraction; Muscle, Smooth; Piperazines; Radioligand Assay; Rats; Rats, Wistar; Receptors, Serotonin; Serotonin Receptor Agonists; Structure-Activity Relationship; Tetrahydronaphthalenes

2007
Structural modifications of N-(1,2,3,4-tetrahydronaphthalen-1-yl)-4-aryl-1-piperazinehexanamides: influence on lipophilicity and 5-HT7 receptor activity. Part III.
    Journal of medicinal chemistry, 2008, Sep-25, Volume: 51, Issue:18

    Topics: Animals; Blood-Brain Barrier; Brain; Mice; Molecular Structure; Piperazines; Receptors, Serotonin

2008
Structure-activity relationships in 1,4-benzodioxan-related compounds. 9. From 1,4-benzodioxane to 1,4-dioxane ring as a promising template of novel alpha1D-adrenoreceptor antagonists, 5-HT1A full agonists, and cytotoxic agents.
    Journal of medicinal chemistry, 2008, Oct-23, Volume: 51, Issue:20

    Topics: Adrenergic alpha-1 Receptor Antagonists; Benzene; Cell Line, Tumor; Cell Survival; Dioxanes; Ethylamines; Humans; Models, Molecular; Molecular Structure; Receptor, Serotonin, 5-HT1A; Receptors, Adrenergic, alpha-1; Serotonin Receptor Agonists; Structure-Activity Relationship

2008
New serotonin 5-HT1A receptor agonists endowed with antinociceptive activity in vivo.
    Journal of medicinal chemistry, 2013, Oct-24, Volume: 56, Issue:20

    Topics: Analgesics; Animals; Binding, Competitive; Cyclic AMP; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP2D6 Inhibitors; HeLa Cells; Heterocyclic Compounds, 2-Ring; Humans; Hydantoins; Kinetics; Ligands; Male; Mice; Models, Chemical; Molecular Structure; Pain; Pain Measurement; Piperazines; Pyridines; Radioligand Assay; Rats; Receptor, Serotonin, 5-HT1A; Serotonin 5-HT1 Receptor Agonists; Serotonin Antagonists

2013
5-HT1-like receptor agonists enhance wakefulness.
    Neuropharmacology, 1992, Volume: 31, Issue:7

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Dose-Response Relationship, Drug; Indoles; Male; Piperazines; Rats; Rats, Wistar; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Sleep; Sleep, REM; Wakefulness

1992
Attenuation of chemically induced defence response by 5-HT1 receptor agonists administered into the periaqueductal gray.
    Psychopharmacology, 1992, Volume: 108, Issue:1-2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aggression; Animals; Exploratory Behavior; Homocysteine; Injections; Male; Periaqueductal Gray; Posture; Rats; Receptors, Serotonin; Serotonin

1992
Serotonin regulates the phase of the rat suprachiasmatic circadian pacemaker in vitro only during the subjective day.
    The Journal of physiology, 1992, Volume: 450

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Biological Clocks; Circadian Rhythm; Culture Techniques; Electrophysiology; Male; Rats; Rats, Inbred Strains; Serotonin; Suprachiasmatic Nucleus

1992
Differential coupling of 5-HT1A receptors occupied by 5-HT or 8-OH-DPAT to adenylyl cyclase.
    Naunyn-Schmiedeberg's archives of pharmacology, 1992, Volume: 346, Issue:4

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adenylyl Cyclases; Cell Line; Cell Membrane; Cells, Cultured; Humans; Receptors, Serotonin; Serotonin; Serotonin Receptor Agonists

1992
Further characterization of the putative 5-HT receptor which mediates blockade of neurogenic plasma extravasation in rat dura mater.
    British journal of pharmacology, 1991, Volume: 103, Issue:2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Blood Pressure; Blood Proteins; Conjunctiva; Dura Mater; Ganglia, Sympathetic; Indoles; Inflammation; Male; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Sulfonamides; Sumatriptan; Sympathectomy; Tetrahydronaphthalenes; Trigeminal Nerve; Vasoconstrictor Agents

1991
Analysis of the 5-HT receptors mediating contractions in the rabbit isolated renal artery.
    British journal of pharmacology, 1991, Volume: 104, Issue:4

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Cocaine; In Vitro Techniques; Indoles; Ketanserin; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Oxidopamine; Phentolamine; Prostaglandin Endoperoxides, Synthetic; Rabbits; Receptors, Serotonin; Renal Artery; Serotonin; Serotonin Antagonists; Sulfonamides; Sumatriptan; Sympathectomy; Tetrahydronaphthalenes; Tyramine; Vasoconstrictor Agents; Vasodilation

1991
The inhibitory effect of trifluoromethylphenylpiperazine on [3H]acetylcholine release in guinea pig hippocampal synaptosomes is mediated by a 5-hydroxytryptamine1 receptor distinct from 1A, 1B, and 1C subtypes.
    Journal of neurochemistry, 1991, Volume: 56, Issue:1

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Acetylcholine; Animals; Guinea Pigs; Hippocampus; Male; Piperazines; Potassium; Quinoxalines; Quipazine; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Synaptosomes; Tetrahydronaphthalenes

1991
Peripheral 5-carboxamidotryptamine (5-CT) elicits drinking by stimulating 5-HT1-like serotonergic receptors in rats.
    Pharmacology, biochemistry, and behavior, 1991, Volume: 38, Issue:2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Dose-Response Relationship, Drug; Drinking Behavior; Feeding Behavior; Indoles; Male; Methysergide; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Stimulation, Chemical; Tetrahydronaphthalenes

1991
Characterization of the 5-HT receptor subtypes involved in the motor behaviours produced by intrathecal administration of 5-HT agonists in rats.
    British journal of pharmacology, 1991, Volume: 103, Issue:2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Clorgyline; Fluoxetine; Injections, Spinal; Ketanserin; Male; Motor Activity; Muscle Contraction; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin; Tetrahydronaphthalenes

1991
Molecular cloning and characterization of a rat brain cDNA encoding a 5-hydroxytryptamine1B receptor.
    The EMBO journal, 1991, Volume: 10, Issue:13

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amino Acid Sequence; Animals; Base Sequence; Binding, Competitive; Brain; Cells, Cultured; Cloning, Molecular; DNA; Humans; Methysergide; Molecular Sequence Data; Nucleic Acid Hybridization; Propranolol; Radioligand Assay; Rats; Receptors, Serotonin; RNA, Messenger; Sequence Alignment; Serotonin; Tetrahydronaphthalenes; Transfection; Yohimbine

1991
5-Hydroxytryptamine-induced vasodilatation in the isolated perfused rat kidney: are endothelial 5-HT1A receptors involved?
    European journal of pharmacology, 1991, Aug-16, Volume: 201, Issue:1

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Acetylcholine; Angiotensin II; Animals; Atrial Natriuretic Factor; Endothelium, Vascular; Kidney; Male; Nitroglycerin; Papaverine; Piperazines; Propanolamines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin; Tetrahydronaphthalenes; Thiophenes; Vasodilation

1991
5-Hydroxytryptamine (5-HT)-induced endothelium-dependent relaxation of pig coronary arteries is mediated by 5-HT receptors similar to the 5-HT1D receptor subtype.
    The Journal of pharmacology and experimental therapeutics, 1990, Volume: 252, Issue:1

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adenylyl Cyclases; Animals; Dinoprost; Dose-Response Relationship, Drug; Endothelium, Vascular; In Vitro Techniques; Radioligand Assay; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Swine; Tetrahydronaphthalenes; Vasodilation

1990
Serotonin-mediated inhibitory postsynaptic potential in guinea-pig prepositus hypoglossi and feedback inhibition by serotonin.
    The Journal of physiology, 1990, Volume: 422

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Action Potentials; Animals; Brain Stem; Dose-Response Relationship, Drug; Feedback; Guinea Pigs; Hypoglossal Nerve; In Vitro Techniques; Male; Neurons; Piperazines; Potassium; Serotonin; Spiperone; Synapses; Tetrahydronaphthalenes; Time Factors

1990
Cardiovascular effects of 5-HT1A receptor agonists injected into the dorsal raphe nucleus of conscious rats.
    European journal of pharmacology, 1990, Jun-21, Volume: 182, Issue:1

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antihypertensive Agents; Atropine Derivatives; Behavior, Animal; Catheterization; Hemodynamics; Injections; Injections, Intravenous; Male; Pindolol; Piperazines; Raphe Nuclei; Rats; Receptors, Serotonin; Serotonin; Tetrahydronaphthalenes

1990
[Hemodynamic profile of 8-OH-DPAT and 5-HT1 agonists in the anesthetized dog].
    Archives des maladies du coeur et des vaisseaux, 1990, Volume: 83, Issue:8

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Analysis of Variance; Anesthesia, General; Animals; Dogs; Hemodynamics; Indoles; Methoxydimethyltryptamines; Receptors, Serotonin; Serotonin; Tetrahydronaphthalenes

1990
Different receptor subtypes mediate the dual presynaptic effects of 5-hydroxytryptamine on peripheral sympathetic neurones.
    Journal of autonomic pharmacology, 1989, Volume: 9, Issue:1

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Cats; Cyproheptadine; Female; Guinea Pigs; Heart Rate; In Vitro Techniques; Ketanserin; Male; Membranes; Metoclopramide; Neurons; Norepinephrine; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Sympathetic Nervous System; Tetrahydronaphthalenes; Tropanes

1989
Serotonin agonists inhibit synaptic potentials in the rat locus ceruleus in vitro via 5-hydroxytryptamine1A and 5-hydroxytryptamine1B receptors.
    The Journal of pharmacology and experimental therapeutics, 1989, Volume: 250, Issue:1

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Bicuculline; Cocaine; Electric Stimulation; In Vitro Techniques; Kinetics; Locus Coeruleus; Male; Neurons; Picrotoxin; Piperazines; Rats; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Synapses; Tetrahydronaphthalenes

1989
Systemic and regional haemodynamic responses to microinjection of 5-HT agonists in the rostral ventrolateral medulla in the rat.
    Neuroscience letters, 1989, Dec-15, Volume: 107, Issue:1-3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Cardiovascular System; Hemodynamics; Medulla Oblongata; Naphthalenes; Rats; Receptors, Serotonin; Serotonin; Tetrahydronaphthalenes

1989
Inhibition of forskolin-stimulated adenylate cyclase activity by 5-HT receptor agonists.
    European journal of pharmacology, 1985, Dec-17, Volume: 119, Issue:3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Colforsin; Dose-Response Relationship, Drug; Guinea Pigs; Hippocampus; In Vitro Techniques; Male; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Spiperone; Tetrahydronaphthalenes

1985
Pharmacological characterization of two 5-hydroxytryptamine receptors coupled to adenylate cyclase in guinea pig hippocampal membranes.
    Molecular pharmacology, 1987, Volume: 31, Issue:4

    Topics: 5-Methoxytryptamine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Adenylyl Cyclases; Animals; Bufotenin; Guinea Pigs; Hippocampus; Kinetics; Male; Mathematics; Membranes; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin; Spiperone; Tetrahydronaphthalenes; Tryptamines

1987
The serotonin (5-HT) autoreceptor in the hippocampus of the rabbit: role of 5-HT biophase concentration.
    Neuropharmacology, 1987, Volume: 26, Issue:8

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Dose-Response Relationship, Drug; Electric Stimulation; Hippocampus; Mathematics; Metergoline; Methiothepin; Methoxydimethyltryptamines; Methysergide; Phentolamine; Pindolol; Quipazine; Rabbits; Receptors, Serotonin; Serotonin; Tetrahydronaphthalenes

1987
A 5-HT1-like receptor mediates a sympathetic ganglionic hyperpolarization.
    European journal of pharmacology, 1987, Dec-15, Volume: 144, Issue:3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Ganglia, Sympathetic; In Vitro Techniques; Ketanserin; Membrane Potentials; Rats; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Tetrahydronaphthalenes; Tropanes

1987
Differential localization of 5-HT1 receptors on myenteric and submucosal neurons.
    The American journal of physiology, 1988, Volume: 255, Issue:5 Pt 1

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Guinea Pigs; In Vitro Techniques; Indicators and Reagents; Intestinal Mucosa; Male; Myenteric Plexus; Neurons; Receptors, Serotonin; Serotonin; Tetrahydronaphthalenes

1988
Differential roles of 5-hydroxytryptamine1A and 5-hydroxytryptamine1B receptor subtypes in modulating spinal nociceptive transmission in mice.
    The Journal of pharmacology and experimental therapeutics, 1993, Volume: 265, Issue:1

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Behavior, Animal; Buspirone; Male; Mice; Morphine; N-Methylaspartate; Pain; Piperazines; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Spinal Cord; Substance P; Synaptic Transmission

1993
Characterization of 5-hydroxytryptamine receptors on the isolated pig basilar artery by functional and radioligand binding studies.
    Japanese journal of pharmacology, 1994, Volume: 65, Issue:3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Basilar Artery; Binding, Competitive; Dose-Response Relationship, Drug; In Vitro Techniques; Ketanserin; Methiothepin; Muscle Contraction; Muscle, Smooth, Vascular; Radioligand Assay; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Structure-Activity Relationship; Swine

1994
Stimulant effects of 5-hydroxytryptamine on guinea pig stomach preparations in vitro.
    European journal of pharmacology, 1994, Sep-01, Volume: 262, Issue:1-2

    Topics: 4-Aminobenzoic Acid; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Atropine; Benzamides; Binding Sites; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Electric Stimulation; Female; Guinea Pigs; In Vitro Techniques; Indoles; Ligands; Male; Metoclopramide; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; para-Aminobenzoates; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Stomach; Tetrodotoxin; Tropanes; Tropisetron

1994
The actions of 5-HT1 agonists and antagonists on nociceptive processing in the rat spinal cord: results from behavioural and electrophysiological studies.
    Brain research, 1994, Oct-24, Volume: 661, Issue:1-2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Injections, Spinal; Male; Neurons; Pain; Piperazines; Rats; Rats, Wistar; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Spinal Cord; Time Factors

1994
Effects of serotonergic agonists on firing rates of photically responsive cells in the hamster suprachiasmatic nucleus.
    Brain research, 1994, Jul-18, Volume: 651, Issue:1-2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Circadian Rhythm; Cricetinae; Light; Male; Metergoline; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Suprachiasmatic Nucleus

1994
Modulation of rhythmic swimming activity in post-embryonic Xenopus laevis tadpoles by 5-hydroxytryptamine acting at 5HT1a receptors.
    Proceedings. Biological sciences, 1994, Jul-22, Volume: 257, Issue:1348

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aging; Animals; Cyproheptadine; Ergolines; Ketanserin; Metamorphosis, Biological; Methysergide; Motor Activity; Piperazines; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Swimming; Xenopus laevis

1994
Modulation by serotonin of the neurons in rat nucleus raphe magnus in vitro.
    Neuroscience, 1993, Volume: 54, Issue:2

    Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Electric Stimulation; Electrophysiology; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Evoked Potentials; In Vitro Techniques; Indoles; Membrane Potentials; Neurons; Quinoxalines; Raphe Nuclei; Rats; Rats, Wistar; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Tropisetron

1993
Quantitative autoradiography of 5-HT1D and 5-HT1E binding sites labelled by [3H]5-HT, in frontal cortex and the hippocampal region of the human brain.
    Brain research, 1994, Feb-28, Volume: 638, Issue:1-2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Autoradiography; Binding, Competitive; Choroid Plexus; Frontal Lobe; Hippocampus; Humans; Kinetics; Neurons; Organ Specificity; Pyramidal Cells; Receptors, Serotonin; Serotonin; Serotonin Receptor Agonists; Tritium

1994
WAY100135: a novel, selective antagonist at presynaptic and postsynaptic 5-HT1A receptors.
    European journal of pharmacology, 1993, Jun-24, Volume: 237, Issue:2-3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Behavior, Animal; Electrophysiology; Female; Guinea Pigs; Hippocampus; Hypothermia; Ileum; Male; Mice; Piperazines; Radioligand Assay; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Stereoisomerism

1993
Endothelial relaxing 5-hydroxytryptamine receptors in the rat jugular vein: similarity with the 5-hydroxytryptamine1C receptor.
    The Journal of pharmacology and experimental therapeutics, 1993, Volume: 264, Issue:2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Endothelium, Vascular; Female; In Vitro Techniques; Jugular Veins; Ketanserin; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Serotonin; Vasodilation

1993
Pharmacological profile of the 5-hydroxytryptamine receptor of Fasciola hepatica body wall muscle.
    Parasitology, 1993, Volume: 106 ( Pt 1)

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Electric Stimulation; Fasciola hepatica; In Vitro Techniques; Isometric Contraction; Muscles; Receptors, Serotonin; Serotonin; Serotonin Receptor Agonists; Tryptamines

1993
Characterization of a postjunctional 5-HT receptor mediating relaxation of guinea-pig isolated ileum.
    European journal of pharmacology, 1995, Jul-14, Volume: 280, Issue:3

    Topics: 5-Methoxytryptamine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Cloning, Molecular; Drug Interactions; Guinea Pigs; Ileum; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; N,N-Dimethyltryptamine; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Substance P; Sumatriptan; Tryptamines

1995
Augmented responses to 5-HT2-receptor-mediated vasoconstrictions in atherosclerotic rabbit common carotid arteries.
    Journal of cardiovascular pharmacology, 1995, Volume: 26, Issue:3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Arteriosclerosis; Carotid Arteries; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelium, Vascular; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Norepinephrine; Piperazines; Potassium Chloride; Rabbits; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Vasoconstriction

1995
5-Hydroxytryptamine 5-HT1D receptors mediating inhibition of cyclic AMP accumulation in Madin-Darby canine kidney (MDCK) cells.
    Naunyn-Schmiedeberg's archives of pharmacology, 1995, Volume: 352, Issue:3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Alprostadil; Animals; Cells, Cultured; Cyclic AMP; Dogs; Dose-Response Relationship, Drug; Drug Interactions; Epithelial Cells; Epithelium; Ketanserin; Kidney Cortex; Methiothepin; Oxadiazoles; Pertussis Toxin; Piperazines; Propranolol; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Structure-Activity Relationship; Sumatriptan; Virulence Factors, Bordetella; Yohimbine

1995
Ketanserin-sensitive depressant actions of 5-HT receptor agonists in the neonatal rat spinal cord.
    British journal of pharmacology, 1995, Volume: 116, Issue:6

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Animals, Newborn; Depression, Chemical; Dioxanes; Dopamine Antagonists; Drug Interactions; Female; Ketanserin; Male; Motor Neurons; Oxadiazoles; Pindolol; Piperazines; Propranolol; Rats; Rats, Wistar; Receptors, Serotonin; Reflex, Monosynaptic; Serotonin; Serotonin Antagonists; Spinal Cord; Spiro Compounds; Sumatriptan

1995
Inhibition of noradrenaline release via presynaptic 5-HT1D alpha receptors in human atrium.
    Naunyn-Schmiedeberg's archives of pharmacology, 1996, Volume: 353, Issue:3

    Topics: 5-Methoxytryptamine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic Uptake Inhibitors; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Cisapride; Corticosterone; Desipramine; Heart Atria; Humans; Indoles; Ketanserin; Male; Middle Aged; Norepinephrine; Oxadiazoles; Piperidines; Receptors, Presynaptic; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Sumatriptan; Tritium; Tryptamines

1996
Functional serotonin 5-HT1D receptors and 5-HT1D beta receptor mRNA expression in human umbilical vein endothelial cells.
    Naunyn-Schmiedeberg's archives of pharmacology, 1995, Volume: 352, Issue:5

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Cells, Cultured; Colforsin; Cyclic AMP; Endothelium, Vascular; Humans; Polymerase Chain Reaction; Receptors, Serotonin; RNA, Messenger; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Sumatriptan; Umbilical Veins

1995
Expression and modulation of 5-hydroxytryptamine1A receptors in P11 cells.
    The Journal of pharmacology and experimental therapeutics, 1996, Volume: 278, Issue:3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adenylyl Cyclases; Animals; Cell Line; Humans; Phosphatidylinositols; Protein Kinase C; Rats; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Second Messenger Systems; Serotonin; Serotonin Receptor Agonists; Signal Transduction; Tetradecanoylphorbol Acetate; Transfection

1996
Identification and characterization of a new serotonergic recognition site with high affinity for 5-carboxamidotryptamine in mammalian brain.
    Journal of neurochemistry, 1997, Volume: 69, Issue:5

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Autoradiography; Binding Sites; Binding, Competitive; Brain; Cerebral Cortex; Ergolines; Ergotamine; Female; Guinea Pigs; Humans; Kinetics; Male; Mammals; Middle Aged; Organ Specificity; Radioligand Assay; Rats; Rats, Wistar; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Tritium

1997
5-HT inhibits lateral entorhinal cortical neurons of the rat in vitro by activation of potassium channel-coupled 5-HT1A receptors.
    Brain research, 1997, Oct-03, Volume: 770, Issue:1-2

    Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; 8-Hydroxy-2-(di-n-propylamino)tetralin; Anesthetics, Local; Animals; Electrophysiology; Entorhinal Cortex; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Lidocaine; Lysine; Male; Neural Inhibition; Neurons; Perforant Pathway; Potassium; Potassium Channels; Propranolol; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin; Serotonin Receptor Agonists; Sympatholytics

1997
Serotonin reduces synaptic excitation in the superficial medial entorhinal cortex of the rat via a presynaptic mechanism.
    The Journal of physiology, 1998, Apr-01, Volume: 508 ( Pt 1)

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Bicuculline; Entorhinal Cortex; Excitatory Postsynaptic Potentials; Female; Guanosine Triphosphate; Hippocampus; In Vitro Techniques; Male; Patch-Clamp Techniques; Piperazines; Potassium Channels; Rats; Rats, Wistar; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Spiperone; Synapses; Synaptic Transmission; Tetrodotoxin

1998
Local administration of serotonin agonists blocks light-induced phase advances of the circadian activity rhythm in the hamster.
    Journal of biological rhythms, 1998, Volume: 13, Issue:3

    Topics: 5,7-Dihydroxytryptamine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Circadian Rhythm; Cricetinae; Light; Male; Mesocricetus; Microinjections; Motor Activity; Photoperiod; Serotonin; Serotonin Receptor Agonists; Suprachiasmatic Nucleus

1998
Effects of maturation, artery size, and chronic hypoxia on 5-HT receptor type in ovine cranial arteries.
    The American journal of physiology, 1998, Volume: 275, Issue:3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aging; Animals; Carotid Artery, Common; Cerebral Arteries; Female; Ketanserin; Male; Methiothepin; Muscle Contraction; Muscle, Smooth, Vascular; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Sheep

1998
The effects of 8-hydroxy-2-(di-n-propylamino)tetralin on the cholinergic contraction in guinea pig and human airways in vitro.
    American journal of respiratory and critical care medicine, 1998, Volume: 158, Issue:5 Pt 1

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Acetylcholine; Animals; Bronchi; Bronchoconstriction; Capsaicin; Cholinergic Fibers; Culture Techniques; Cyclohexane Monoterpenes; Dose-Response Relationship, Drug; Electric Stimulation; Guinea Pigs; Humans; Indoles; Ketanserin; Methysergide; Muscle Contraction; Muscle, Smooth; Neuropeptides; Pindolol; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Thiazoles; Trachea; Tropisetron

1998
Effects of the non-selective 5-HT receptor agonist, 5-carboxamidotryptamine, on plasma glucose levels in rats.
    European journal of pharmacology, 1998, Oct-16, Volume: 359, Issue:1

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Blood Glucose; Glucagon; Hyperglycemia; Insulin; Male; Propranolol; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Vasodilator Agents

1998
Selective labelling of 5-HT7 receptor recognition sites in rat brain using [3H]5-carboxamidotryptamine.
    Neuropharmacology, 1998, Volume: 37, Issue:12

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Binding, Competitive; Brain; Clozapine; Indoles; Kinetics; Male; Pindolol; Piperazines; Pyridines; Radioligand Assay; Rats; Rats, Wistar; Receptors, Serotonin; Recombinant Proteins; Serotonin; Sulfonamides; Tritium

1998
Putative 5-ht5 receptors: localization in the mouse CNS and lack of effect in the inhibition of dural protein extravasation.
    Annals of the New York Academy of Sciences, 1998, Dec-15, Volume: 861

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Autoradiography; Binding Sites; Blood Proteins; Brain; Crosses, Genetic; Female; Lysergic Acid Diethylamide; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Organ Specificity; Oxadiazoles; Piperazines; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Trigeminal Ganglion; Tritium

1998
Activation of 5-HT1B receptors in the nucleus accumbens reduces amphetamine-induced enhancement of responding for conditioned reward.
    Psychopharmacology, 1999, Volume: 142, Issue:2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamine; Animals; Conditioning, Psychological; Indoles; Male; Nucleus Accumbens; Pyridines; Pyrroles; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1B; Receptors, Serotonin; Reward; Serotonin; Serotonin Receptor Agonists; Water

1999
Characterisation of 5-HT receptors in human coronary arteries by molecular and pharmacological techniques.
    European journal of pharmacology, 1999, May-07, Volume: 372, Issue:1

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Cardiovascular System; Coronary Vessels; Dose-Response Relationship, Drug; Gene Expression; Humans; Immunohistochemistry; In Vitro Techniques; Ketanserin; Methiothepin; Oxazoles; Oxazolidinones; Receptor, Serotonin, 5-HT1B; Receptor, Serotonin, 5-HT1D; Receptors, Serotonin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Sumatriptan; Tissue Distribution; Tryptamines; Vasoconstriction

1999
Serotonergic modulation of hyperpolarization-activated current in acutely isolated rat dorsal root ganglion neurons.
    The Journal of physiology, 1999, Jul-15, Volume: 518 ( Pt 2)

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Action Potentials; Animals; Cell Size; Cyclic Nucleotide-Gated Cation Channels; Dopamine Antagonists; Ganglia, Spinal; Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels; In Vitro Techniques; Ion Channels; Male; Membrane Potentials; Neurons, Afferent; Patch-Clamp Techniques; Pindolol; Potassium Channels; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Reverse Transcriptase Polymerase Chain Reaction; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Spiperone

1999
Involvement of 5-HT1B receptors in collar-induced hypersensitivity to 5-hydroxytryptamine of the rabbit carotid artery.
    British journal of pharmacology, 1999, Volume: 127, Issue:6

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Braces; Carotid Arteries; Dose-Response Relationship, Drug; Hypersensitivity; In Vitro Techniques; Ketanserin; Male; Methysergide; Oxadiazoles; Piperazines; Potassium Chloride; Rabbits; Receptor, Serotonin, 5-HT1B; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Ritanserin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Spiperone; Sumatriptan; Tryptamines; Vasoconstriction

1999
Effects of antidepressants on 5-HT7 receptor regulation in the rat hypothalamus.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 1999, Volume: 21, Issue:3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antidepressive Agents; Circadian Rhythm; Depression; Down-Regulation; Hypothalamus; Male; Proto-Oncogene Proteins c-fos; Rats; Rats, Wistar; Receptors, Serotonin; Serotonin; Serotonin Receptor Agonists; Suprachiasmatic Nucleus

1999
5-Hydroxytryptamine(1A) receptor-stimulated [(35)S]GTPgammaS binding in rat brain: absence of regional differences in coupling efficiency.
    The Journal of pharmacology and experimental therapeutics, 2000, Volume: 292, Issue:2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Autoradiography; Brain; Dose-Response Relationship, Drug; Drug Interactions; Guanosine 5'-O-(3-Thiotriphosphate); In Vitro Techniques; Male; Phenoxybenzamine; Piperazines; Protein Binding; Pyridines; Quinolines; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Tryptamines

2000
Characterisation of a 5-HT(7) binding site in mouse ileum.
    European journal of pharmacology, 2000, Jan-17, Volume: 387, Issue:3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Binding Sites; Ergolines; Female; Ileum; Male; Mice; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; Serotonin; Serotonin Antagonists

2000
The effect of SB-269970, a 5-HT(7) receptor antagonist, on 5-HT release from serotonergic terminals and cell bodies.
    British journal of pharmacology, 2001, Volume: 132, Issue:7

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Brain; Cerebral Cortex; Dose-Response Relationship, Drug; Guinea Pigs; In Vitro Techniques; Male; Mediodorsal Thalamic Nucleus; Phenols; Piperidones; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Spiro Compounds; Sulfonamides; Tritium

2001
Pharmacological characterization of serotonin receptor subtypes modulating primary afferent input to deep dorsal horn neurons in the neonatal rat.
    British journal of pharmacology, 2001, Volume: 132, Issue:8

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Animals, Newborn; Ligands; Neurons, Afferent; Patch-Clamp Techniques; Posterior Horn Cells; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Synapses

2001
Reconsideration of 5-hydroxytryptamine (5-HT)(7) receptor distribution using [(3)H]5-carboxamidotryptamine and [(3)H]8-hydroxy-2-(di-n-propylamino)tetraline: analysis in brain of 5-HT(1A) knockout and 5-HT(1A/1B) double-knockout mice.
    The Journal of pharmacology and experimental therapeutics, 2002, Volume: 302, Issue:1

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Autoradiography; Brain; Brain Chemistry; Mice; Mice, Knockout; Phenols; Radioligand Assay; Receptor, Serotonin, 5-HT1B; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Sulfonamides

2002
Pharmacology of serotonin receptors modulating electrically-induced [3h]-norepinephrine release from isolated mammalian iris-ciliary bodies.
    Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 2002, Volume: 18, Issue:4

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Biguanides; Cattle; Ciliary Body; Dose-Response Relationship, Drug; Electric Stimulation; Humans; In Vitro Techniques; Iris; Norepinephrine; Piperidines; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Sulfonamides; Tritium; Tropanes

2002
Role of serotonin1A receptors on the modulation of rat spinal mono-synaptic reflexes in vitro.
    Neuroscience letters, 2002, Dec-06, Volume: 334, Issue:1

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Electric Stimulation; Organ Culture Techniques; Piperazines; Rats; Rats, Wistar; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Reflex, Monosynaptic; Serotonin; Serotonin Agents; Serotonin Antagonists; Serotonin Receptor Agonists; Spinal Cord; Spinal Nerve Roots

2002
Serotonin receptors involved in vasopressin and oxytocin secretion.
    Journal of neuroendocrinology, 2003, Volume: 15, Issue:3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Dose-Response Relationship, Drug; Hypothalamus, Anterior; Injections, Intraventricular; Male; Oxytocin; Paraventricular Hypothalamic Nucleus; Rats; Rats, Wistar; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Vasopressins

2003
Radioligand binding analysis of knockout mice reveals 5-hydroxytryptamine(7) receptor distribution and uncovers 8-hydroxy-2-(di-n-propylamino)tetralin interaction with alpha(2) adrenergic receptors.
    Neuroscience, 2004, Volume: 124, Issue:4

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Autoradiography; Binding Sites; Brain; Mice; Mice, Knockout; Osmolar Concentration; Radioligand Assay; Receptors, Adrenergic, alpha-2; Receptors, Serotonin; Serotonin; Serotonin Receptor Agonists; Tissue Distribution

2004
Aging and SB-269970-A, a selective 5-HT7 receptor antagonist, attenuate circadian phase advances induced by microinjections of serotonergic drugs in the hamster dorsal raphe nucleus.
    Brain research, 2004, May-15, Volume: 1008, Issue:1

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Age Factors; Analysis of Variance; Animals; Circadian Rhythm; Cricetinae; Dose-Response Relationship, Drug; Drug Interactions; Male; Mesocricetus; Microinjections; Phenols; Raphe Nuclei; Serotonin; Serotonin Agents; Serotonin Antagonists; Sulfonamides

2004
5-HT7 receptor subtype as a mediator of the serotonergic regulation of luteinizing hormone release in the zona incerta.
    European journal of pharmacology, 2004, Apr-26, Volume: 491, Issue:1

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Female; Luteinizing Hormone; Male; Ovariectomy; Phenols; Piperazines; Rats; Rats, Wistar; Receptors, Serotonin; Ritanserin; Serotonin; Serotonin 5-HT1 Receptor Antagonists; Serotonin 5-HT2 Receptor Antagonists; Serotonin Antagonists; Serotonin Receptor Agonists; Subthalamus; Sulfonamides

2004
Functional expression of the serotonin 5-HT7 receptor in human glioblastoma cell lines.
    British journal of pharmacology, 2004, Volume: 143, Issue:3

    Topics: 5-Methoxytryptamine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Blotting, Western; Cell Line, Tumor; CHO Cells; Cricetinae; Cricetulus; Cyclic AMP; Dose-Response Relationship, Drug; Gene Expression Regulation, Neoplastic; Glioblastoma; Humans; Protein Isoforms; Receptors, Serotonin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Serotonin

2004
5-HT receptors couple to activation of Akt, but not extracellular-regulated kinase (ERK), in cultured hippocampal neurons.
    Journal of neurochemistry, 2005, Volume: 93, Issue:4

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Analysis of Variance; Animals; Blotting, Western; Brain-Derived Neurotrophic Factor; Cells, Cultured; CHO Cells; Cricetinae; Cricetulus; Dose-Response Relationship, Drug; Drug Interactions; Embryo, Mammalian; Enzyme Activation; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Fluorescent Antibody Technique; Hippocampus; Neurons; Pertussis Toxin; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Receptor, Serotonin, 5-HT1A; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Time Factors; Transfection

2005
Serotonin 5-HT7 receptors coupled to induction of interleukin-6 in human microglial MC-3 cells.
    Neuropharmacology, 2005, Volume: 49, Issue:1

    Topics: 5-Methoxytryptamine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Blotting, Northern; Blotting, Western; Cell Line; Cyclic AMP; Dose-Response Relationship, Drug; Drug Interactions; Gene Expression Regulation; Humans; Interleukin-6; Microglia; Phenols; Receptors, Serotonin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Serotonin; Serotonin Agents; Serotonin Antagonists; Sulfonamides; Transfection

2005
Effect of 5-hydroxytryptamine on neurogenic vasoconstriction in the isolated, autoperfused hindquarters of the rat.
    Clinical and experimental pharmacology & physiology, 2005, Volume: 32, Issue:10

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Biguanides; Biphenyl Compounds; Dose-Response Relationship, Drug; Electric Stimulation; Hindlimb; In Vitro Techniques; Infusions, Intravenous; Male; Methiothepin; Oxadiazoles; Perfusion; Piperazines; Pressure; Quinoxalines; Rats; Rats, Wistar; Ritanserin; Serotonin; Serotonin 5-HT1 Receptor Agonists; Serotonin 5-HT2 Receptor Agonists; Serotonin 5-HT3 Receptor Agonists; Serotonin Agents; Serotonin Antagonists; Serotonin Receptor Agonists; Tryptamines; Vasoconstriction

2005
Gender-dependent regulation of G-protein-gated inwardly rectifying potassium current in dorsal raphe neurons in knock-out mice devoid of the 5-hydroxytryptamine transporter.
    Journal of neurobiology, 2006, Volume: 66, Issue:13

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Drug Interactions; Electric Stimulation; Female; G Protein-Coupled Inwardly-Rectifying Potassium Channels; Guanylyl Imidodiphosphate; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Neurons; Piperazines; Pyridines; Raphe Nuclei; Serotonin; Serotonin Agents; Serotonin Plasma Membrane Transport Proteins; Sex Characteristics; Time Factors

2006
Attenuating effects of prior oestradiol benzoate priming on 5-HT-mediated lordosis behavior in rats are dose-dependent.
    Acta physiologica Hungarica, 2007, Volume: 94, Issue:3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Brain; Dopamine Antagonists; Dose-Response Relationship, Drug; Estradiol; Female; Male; Ovariectomy; Phenols; Piperazines; Posture; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT1A; Receptors, Serotonin; Reflex; Serotonin; Serotonin Receptor Agonists; Sexual Behavior, Animal; Sulfonamides

2007
Diabetes-induced changes in 5-hydroxytryptamine modulation of vagally-induced bradycardia in rat heart.
    Clinical and experimental pharmacology & physiology, 2007, Volume: 34, Issue:11

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Acetylcholine; Animals; Biphenyl Compounds; Blood Glucose; Bradycardia; Cholinergic Agents; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Electric Stimulation; Ergolines; Heart; Heart Rate; Injections, Intravenous; Male; Methiothepin; Oxadiazoles; Piperazines; Pyridines; Rats; Rats, Wistar; Receptors, Serotonin, 5-HT1; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Tryptamines; Vagus Nerve

2007
Neurochemical, behavioral, and physiological effects of pharmacologically enhanced serotonin levels in serotonin transporter (SERT)-deficient mice.
    Psychopharmacology, 2008, Volume: 201, Issue:2

    Topics: 5-Hydroxytryptophan; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Brain; Brain Chemistry; Catecholamines; Clorgyline; Dopamine Uptake Inhibitors; Drug Synergism; Drug Therapy, Combination; Female; Hydroxyindoleacetic Acid; Hypothermia; Male; Mice; Mice, Knockout; Monoamine Oxidase Inhibitors; Phenols; Piperazines; Pyridines; Serotonin; Serotonin 5-HT1 Receptor Antagonists; Serotonin Plasma Membrane Transport Proteins; Serotonin Receptor Agonists; Serotonin Syndrome; Sulfonamides; Tranylcypromine

2008
Evidence that 5-hydroxytryptamine(7) receptors play a role in the mediation of afferent transmission within the nucleus tractus solitarius in anaesthetized rats.
    British journal of pharmacology, 2009, Volume: 158, Issue:5

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Action Potentials; Afferent Pathways; Anesthesia; Animals; Electric Stimulation; Heart; Lung; Male; Neurons; Piperazines; Piperidines; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Serotonin; Serotonin 5-HT1 Receptor Agonists; Serotonin 5-HT1 Receptor Antagonists; Serotonin Antagonists; Solitary Nucleus; Sulfonamides; Synaptic Transmission; Vagus Nerve

2009
Serotonin modulates glutamatergic transmission in the rat olfactory tubercle.
    The European journal of neuroscience, 2010, Volume: 31, Issue:4

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Citalopram; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; In Vitro Techniques; Male; Olfactory Pathways; Oxadiazoles; Quinoxalines; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Receptor Agonists; Synaptic Transmission; Tryptamines

2010