8-hydroxy-2-(di-n-propylamino)tetralin has been researched along with 4-iodo-2,5-dimethoxyphenylisopropylamine in 195 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (2.56) | 18.7374 |
| 1990's | 101 (51.79) | 18.2507 |
| 2000's | 64 (32.82) | 29.6817 |
| 2010's | 25 (12.82) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Frescas, S; Gudelsky, GA; Huang, X; Marona-Lewicka, D; Nash, JF; Nichols, DE; Roth, BL | 1 |
| Adham, N; Bard, J; Branchek, TA; Durkin, M; Hartig, PR; Kao, HT; Olsen, M; Schecter, LE; Urquhart, D; Weinshank, RL | 1 |
| Audia, JE; Baez, M; Cohen, ML; Kursar, JD; Lucaites, VL; Nelson, DL; Nissen, JS; Schenck, KW; Wainscott, DB | 1 |
| Barker, EL; Blair, JB; Cumbay, MG; Kurrasch-Orbaugh, D; Marona-Lewicka, D; Nichols, DE; Watts, VJ | 1 |
| Kurrasch-Orbaugh, D; Laban, U; Marona-Lewicka, D; Nichols, DE | 1 |
| Glennon, RA | 3 |
| Bai, F; Johnstone, EM; Little, SP; Nelson, DL; Su, C; Varga, G; Yin, T | 1 |
| Altenbach, RJ; Brioni, JD; Carr, TL; Chandran, P; Cowart, MD; Esbenshade, TA; Honore, P; Hsieh, GC; Lewis, LG; Liu, H; Manelli, AM; Marsh, KC; Milicic, I; Miller, TR; Strakhova, MI; Vortherms, TA; Wakefield, BD; Wetter, JM; Witte, DG | 1 |
| Colau, D; Dolusić, E; Frédérick, R; Larrieu, P; Masereel, B; Moineaux, L; Pilotte, L; Pochet, L; Stroobant, V; Van den Eynde, B; Wouters, J | 1 |
| Anzini, M; Brogi, S; Butini, S; Campiani, G; Cappelli, A; Caselli, G; Castriconi, F; Gemma, S; Giordani, A; Giorgi, G; Giuliani, G; Lanza, M; Letari, O; Makovec, F; Manini, M; Mennuni, L; Valenti, S | 1 |
| Belyakov, S; Dambrova, M; Kazoka, H; Kuznecovs, J; Lebedev, A; Liepinsh, E; Mishnev, A; Orlova, N; Ponomaryov, Y; Vavers, E; Veinberg, G; Vikainis, S; Vilskersts, R; Vorona, M; Zvejniece, L | 1 |
| Bednarski, M; Gunia-Krzyżak, A; Marona, H; Nitek, W; Pękala, E; Powroźnik, B; Słoczyńska, K; Walczak, M; Waszkielewicz, AM; Żesławska, E | 1 |
| Filipek, B; Gunia-Krzyżak, A; Marona, H; Nitek, W; Pańczyk, K; Pękala, E; Rapacz, A; Słoczyńska, K; Waszkielewicz, AM; Żelaszczyk, D; Żesławska, E | 1 |
| Cowen, PJ; Ellis, PM; Gartside, SE; Sharp, T | 1 |
| Fukuda, H; Nagao, T; Ono, H; Yamazaki, J | 1 |
| Alvarez Sanz, MC; Levy, AD; Li, Q; Rittenhouse, PA; Van de Kar, LD | 1 |
| Reid, A; Sawynok, J | 1 |
| Eide, PK | 1 |
| Coscina, DV; Fletcher, PJ; Ming, ZH; Zack, MH | 1 |
| Hasegawa, H; Nakamura, M; Wada, Y; Yamaguchi, N | 1 |
| Mokler, DJ; Sullivan, SA; Winterson, BJ | 1 |
| Miletic, V; Tan, H | 1 |
| Kow, LM; Pfaff, DW; Tsai, YF; Wang, L | 1 |
| Pranzatelli, MR | 1 |
| Baudrie, V; Broqua, P; Chaouloff, F; Layeillon, C | 1 |
| Huang, X; Johnson, MP; Nichols, DE; Tomaszewski, Z | 1 |
| Bagdy, G; Murphy, DL; Sved, AF; Szemeredi, K | 1 |
| Eide, PK; Hole, K | 1 |
| Crisp, T; Donepudi, HB; Perni, VC; Spanos, LJ; Stafinsky, JL; Uram, M | 1 |
| Barzizza, A; Folghera, S; Maura, G; Raiteri, M | 1 |
| Fone, KC; Marsden, CA; Robinson, AJ | 1 |
| Cornelissen, JC; de Kloet, ER; Schipper, J; Sijbesma, H | 1 |
| Pluchino, RS; Pranzatelli, MR | 1 |
| Garratt, JC; Kidd, EJ; Marsden, CA | 1 |
| Baimbridge, KG; Klancnik, JM; Obenaus, A; Phillips, AG | 1 |
| Berendsen, HH; Broekkamp, CL | 4 |
| Ismail, H; Marsden, CA; Upton, N; Wright, IK | 1 |
| Carbone, R; Guido, M; Maura, G; Pestarino, M; Raiteri, M | 1 |
| Ashby, CR; Jiang, LH; Kasser, RJ; Wang, RY | 1 |
| Holtman, JR; King, KA | 1 |
| Geyer, MA; Tapson, GS; Wing, LL | 1 |
| Dollison, AM; Huang, YY; Pranzatelli, MR | 1 |
| Frambes, NA; Kirstein, CL; Moody, CA; Spear, LP | 1 |
| Darmani, NA; Glennon, RA; Martin, BR; Pandey, U | 1 |
| Simansky, KJ; Vaidya, AH | 1 |
| Jackson, DA; White, SR | 1 |
| Dun, NJ; Wang, MY | 1 |
| Bagdy, G; Calogero, AE; Chrousos, GP; Gold, PW; Szemeredi, K; Tartaglia, ME | 1 |
| Arnt, J; Hyttel, J | 1 |
| Gudelsky, GA; Meltzer, HY; Nash, JF | 1 |
| Bagdy, G; Calogero, AE; Murphy, DL; Szemeredi, K | 1 |
| Harris, LT; McCall, RB; Patel, BN | 1 |
| Björklund, M; Jäkälä, P; Kaukua, J; Koivisto, E; Riekkinen, P; Sirviö, J | 1 |
| Baumann, MH; Becketts, KM; Rothman, RB | 1 |
| Graeff, FG; Nogueira, RL | 1 |
| Gower, AJ; Kendall, DA; Marsden, CA; Robson, L | 1 |
| De Almeida, RM; Lucion, AB | 1 |
| Caldarola-Pastuszka, M; Maswood, S; Uphouse, L | 1 |
| Audinot, V; Brocco, M; Gobert, A; Millan, MJ; Schreiber, R; Veiga, S | 1 |
| Riekkinen, P | 1 |
| Bovetto, S; Richard, D | 1 |
| Geyer, MA; Krebs, KM | 1 |
| Ashby, CR; Wang, RY; Zhang, JY | 1 |
| Cools, AR; Ellenbroek, BA; Prinssen, EP | 1 |
| Koike, H; Matsuki, N; Saito, H | 1 |
| Ashby, CR; Edwards, E; Wang, RY; Zhang, JY | 1 |
| Bidzinski, A; Jessa, M; Kostowski, W; Nazar, M; Palejko, W; Plaznik, A; Stefanski, R | 1 |
| Dursun, SM; Handley, SL | 1 |
| Andrade, M; Caldarola-Pastuszka, M; Maswood, S; Uphouse, L | 1 |
| Huang, X; Marona-Lewicka, D; Nichols, DE; Pfaff, RC | 1 |
| Berg, M; Johansson-Wallsten, CE; Meyerson, BJ | 1 |
| Grahame-Smith, DG; Leslie, RA; Moorman, JM | 1 |
| Jeffrey, JJ; Rydelek-Fitzgerald, L; Teitler, M; Wilcox, BD | 1 |
| Bagdy, G; Kalogeras, KT | 1 |
| Helke, CJ; Nickolaus, S; Thor, KB | 1 |
| Bagdy, G; Calogero, AE; D'Agata, R; Moncada, ML | 1 |
| Lund, A; Mjellem, N | 1 |
| Eison, AS; Freeman, RP; Gylys, JA; Wright, RN | 1 |
| Heckman, CJ; Lee, RH; Miller, JF; Paul, KD; Rymer, WZ | 1 |
| Albonetti, E; Farabollini, F; González, MI; Siddiqui, A; Wilson, CA | 1 |
| Endo, K; Hori, Y; Takahashi, T | 1 |
| Friedman, E; Tilakaratne, N | 1 |
| Berendsen, HH; Broekkamp, CL; Kester, RC; Peeters, BW | 1 |
| Capodilupo, JG; Carlock, LR; Walker, PD; Wolf, WA | 1 |
| Hasegawa, Y; Ono, H | 1 |
| Ahlenius, S; Alster, P; Hillegaart, V; Uvnäs-Moberg, K | 1 |
| Koshino, Y; Nakamura, M; Shiraishi, J; Wada, Y | 1 |
| Aghajanian, GK; Duman, RS; Marek, GJ; Vaidya, VA | 1 |
| Henley, WN; Vladic, F | 1 |
| Charakchieva-Minol, S; Chojnacka-Wójcik, E; Dereń-Wesołek, A; Duszyńska, B; Kowalska, T; Kowalski, P; Kłodzińska, A; Majka, Z; Misztal, S; Mokrosz, JL; Mokrosz, MJ; Tatarczyńska, E | 1 |
| Assié, MB; Kleven, MS; Koek, W | 1 |
| Kitamura, Y; Nagatani, T; Takao, K; Yamawaki, S | 1 |
| Maswood, N; Uphouse, L | 1 |
| Meltzer, HY; Willins, DL | 1 |
| Chu, K; Ghosh, S; Kant, GJ; Wylie, RM | 1 |
| Buhot, MC; Compan, V; Daszuta, A; Segu, L | 1 |
| Ahlenius, S; Larsson, K | 1 |
| Haapalinna, A; Koivisto, E; MacDonald, E; Riekkinen, P; Ruotsalainen, S; Sirviö, J; Stefanski, R | 1 |
| Ashby, CR; Katsumori, H; Minabe, Y; Watanabe, K | 1 |
| Caldarola-Pastuszka, M; Maswood, N; Uphouse, L | 1 |
| Baumann, MH; Rothman, RB | 1 |
| Gervais, J; Rouillard, C; Tremblay, PO | 1 |
| Davidowa, H; Heidel, E | 1 |
| Geyer, MA; Krebs-Thomson, K | 1 |
| Ahmad, B; Darmani, NA | 1 |
| Evenden, J; Meyerson, B | 1 |
| Chung, M; Fraga, K; Frieman, VB; Illuzzi, FA; O'Gara, BA; Portnoy, AD | 1 |
| Mørk, A; Sánchez, C | 1 |
| Curzon, G; Heslop, KE | 1 |
| Evenden, JL; Ryan, CN | 1 |
| Deis, RP; Hole, D; Jahn, GA; Kalia, V; Wilson, CA | 1 |
| Abe, K; Edagawa, Y; Saito, H | 1 |
| Bonfante, V; Dall'Olio, R; Gaggi, R; Gandolfi, O | 1 |
| Placantonakis, DG; Schwarz, C; Welsh, JP | 1 |
| Dall'Olio, R; Gaggi, R; Gandolfi, O | 2 |
| Kurasawa, M; Nakamura, K | 1 |
| Negrev, N; Zhelyazkova-Savova, MD | 1 |
| Liang, SL; Pan, JT | 1 |
| Koch, T; Korf, J; Kuipers, SD; Sebens, JB; Ter Horst, GJ | 1 |
| Handley, SL; McCreary, AC | 1 |
| Breese, GR; Knapp, DJ; Overstreet, DH; Sim-Selley, LJ | 1 |
| Goto, F; Ishizaki, K; Obata, H; Saito, S; Sasaki, M | 1 |
| Costall, B; Neill, JC; Wilson, AW | 1 |
| Moerschbaecher, JM; Winsauer, PJ | 1 |
| Bonaccorso, S; Fowler, WL; Ichikawa, J; Ishii, H; Meltzer, HY; O'Laughlin, IA | 1 |
| Akesson, P; Engel, JA; Olausson, P; Söderpalm, B | 1 |
| Goto, F; Ishizaki, K; Obata, H; Sasaki, M | 1 |
| Battaglia, G; D'Souza, D; Garcia, F; Muma, NA; Raap, DK; Van de Kar, LD; Zhang, Y | 1 |
| Chang, YH; Liao, RM | 1 |
| Blier, P; Szabo, ST | 2 |
| Azampanah, A; Fletcher, PJ; Korth, KM | 1 |
| Hirano, H; Matsuda, Y; Watanabe, Y | 1 |
| Almeida, LP; Cabral, AH; Jacob, CA; Landeira-Fernandez, J; Magierek, V; Nogueira, RL; Ramos, PL; Zangrossi, H; Zanoveli, JM | 1 |
| Albers, HE; Caldwell, HK | 1 |
| Aguilar, E; Gonzalez, LC; Pinilla, L; Tena-Sempere, M | 1 |
| Bobula, B; Hess, G; Tokarski, K; Zahorodna, A | 1 |
| Nogueira, RL; Zangrossi, H; Zanoveli, JM | 2 |
| Battaglia, G; Carrasco, GA; D'Souza, DN; Damjanoska, KJ; Dudas, B; Garcia, F; Gray, TS; Muma, NA; Sullivan Hanley, NR; Van de Kar, LD; Zainelli, GM; Zhang, Y | 1 |
| Hay-Schmidt, A; Kiss, A; Mikkelsen, JD | 1 |
| Guimarães, FS; Moreira, FA | 2 |
| Giarola, AS; Large, CH; Sokal, DM | 1 |
| Höglund, AU; Kommalage, M | 1 |
| Blokland, A; Lieben, C; Sik, A | 1 |
| Chandler, SH; Hsiao, CF; Wu, N | 1 |
| Grandoso, L; Pineda, J; Torrecilla, M; Ugedo, L | 1 |
| Hochman, S; Machacek, DW; Sawchuk, M; Shay, BL | 1 |
| Asgari, K; Body, S; Bradshaw, CM; Fone, KC; Szabadi, E; Zhang, Z | 1 |
| de Bortoli, VC; Nogueira, RL; Zangrossi, H | 2 |
| Duron, B; Glérant, JC; Khater-Boidin, J; Salzmann, F | 1 |
| Jazvinsćak Jembrek, M; Lazić, J; Pericić, D; Svob Strac, D | 1 |
| Araki, H; Bekku, N; Yoshimura, H | 1 |
| Hess, G; Zahorodna, A | 1 |
| Araki, H; Fujitani, Y; Gomita, Y; Kitagawa, K; Kitamura, Y; Sendou, T; Shibata, K | 1 |
| Lincoln, C; Selvamani, A; Uphouse, L | 1 |
| Legutko, B; Rogóz, Z; Skuza, G | 1 |
| Gajendiran, M | 2 |
| Aso, E; Castro, E; Maldonado, R; Martín, M; Mato, S; Pazos, A; Valverde, O | 1 |
| Barman, SM; Gebber, GL; Orer, HS | 1 |
| Crews, D; Dias, BG | 1 |
| Ten Eyck, GR | 1 |
| France, CP; Li, JX | 1 |
| Becnel, J; Johnson, O; Nichols, CD | 1 |
| Blier, P; El Mansari, M; Ghanbari, R; Shahid, M | 1 |
| Cools, AR; Groot Kormelink, T; Steenhof, M; Veenvliet, JV; Verheij, MM | 1 |
| Chaiseha, Y; El Halawani, ME; Kang, SW; Kosonsiriluk, S; Leclerc, B; Sartsoongnoen, N | 1 |
| Gomes, KS; Nunes-De-Souza, RL | 1 |
| Anselmo-Franci, JA; Bícego, KC; de Souza Moreno, V; Gargaglioni, LH; Szawka, RE | 1 |
| Ermani, M; Freo, U; Merico, A; Ori, C | 1 |
| Akagawa, K; Fujiwara, T; Kofuji, T; Snada, M; Yoshikawa, T | 1 |
| Geijo-Barrientos, E; Troca-Marín, JA | 1 |
| Blasio, A; Cottone, P; Kaminski, BJ; Narayan, AR; Sabino, V; Steardo, L | 1 |
| Gocho, Y; Saitow, F; Sakai, A; Suzuki, H; Yanagawa, Y | 1 |
| Fox, MA; Hall, FS; Murphy, DL; Panessiti, MG; Uhl, GR | 1 |
| Acher, FC; Gruca, P; Lasoń-Tyburkiewicz, M; Papp, M; Pilc, A; Sławińska, A; Wierońska, JM | 1 |
| Gogos, A; Thwaites, SJ; Van den Buuse, M | 1 |
| Atzori, M; Dinh, L; Galindo-Charles, L; García-Oscos, F; Pérez Padilla, EA; Pineda, JC; Salgado, H; Torres-Ramírez, O | 1 |
| France, CP; Rice, KC; Serafine, KM | 1 |
| Geijo-Barrientos, E; Rovira, V | 1 |
| Gołembiowska, K; Kamińska, K; Kreiner, G; Noworyta-Sokołowska, K; Rogóż, Z | 1 |
| Browne, CJ; Fletcher, PJ; Higgins, GA; Soko, AD; Zeeb, FD | 1 |
| Iha, HA; Kunisawa, N; Matsubara, N; Nomura, Y; Ohno, Y; Onishi, M; Shimizu, S | 1 |
| Banas, SM; Belmer, A; Diaz, SL; Doly, S; Fernandez, SP; Guiard, BP; Mameli, M; Maroteaux, L; Moutkine, I; Muzerelle, A; Pitychoutis, PM; Quentin, E; Roumier, A; Tchenio, A | 1 |
| Cruz-Martínez, AM; Escartín-Pérez, RE; Florán-Garduño, B; López-Alonso, VE; Mancilla-Díaz, JM; Tejas-Juárez, JG | 1 |
| Alemany-González, M; Chanovas, J; Delgado-Sallent, C; Gener, T; Nebot, P; Puig, MV; Tauste Campo, A | 1 |
2 review(s) available for 8-hydroxy-2-(di-n-propylamino)tetralin and 4-iodo-2,5-dimethoxyphenylisopropylamine
| Article | Year |
|---|---|
Higher-end serotonin receptors: 5-HT(5), 5-HT(6), and 5-HT(7).
Topics: Animals; Humans; Ligands; Receptors, Serotonin; Serotonin Agents; Serotonin Antagonists; Serotonin Receptor Agonists | 2003 |
Selective breeding of 5-HT(1A) receptor-mediated responses: application to emotion and receptor action.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Behavior, Animal; Breeding; Emotions; Guanosine 5'-O-(3-Thiotriphosphate); Hypothermia; Mice; Mice, Knockout; Rats; Rats, Mutant Strains; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Antagonists; Serotonin Receptor Agonists | 2000 |
193 other study(ies) available for 8-hydroxy-2-(di-n-propylamino)tetralin and 4-iodo-2,5-dimethoxyphenylisopropylamine
| Article | Year |
|---|---|
1-(2,5-Dimethoxy-4-(trifluoromethyl)phenyl)-2-aminopropane: a potent serotonin 5-HT2A/2C agonist.
Topics: 3T3 Cells; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Binding, Competitive; Cell Line; Discrimination, Psychological; Frontal Lobe; Hippocampus; Iodine Radioisotopes; Ketanserin; Male; Mice; Phenethylamines; Phosphatidylinositols; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Serotonin; Serotonin Receptor Agonists; Tritium | 1994 |
Cloning of another human serotonin receptor (5-HT1F): a fifth 5-HT1 receptor subtype coupled to the inhibition of adenylate cyclase.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Amino Acid Sequence; Animals; Base Sequence; Brain Chemistry; Cloning, Molecular; Colforsin; Dose-Response Relationship, Drug; Gene Library; Guinea Pigs; Humans; Indoles; Lymphocytes; Molecular Sequence Data; Receptors, Serotonin; RNA, Messenger; Sequence Homology, Amino Acid; Serotonin; Serotonin Receptor Agonists; Spiperone; Sulfonamides; Sumatriptan; Tissue Distribution | 1993 |
Pharmacological characteristics of the newly cloned rat 5-hydroxytryptamine2F receptor.
Topics: Animals; Binding Sites; Cell Line; Cloning, Molecular; Gastric Fundus; Inositol 1,4,5-Trisphosphate; Male; Muscle Contraction; Muscle, Smooth; Radioligand Assay; Rats; Rats, Wistar; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Temperature | 1993 |
Effect of ring fluorination on the pharmacology of hallucinogenic tryptamines.
Topics: 3T3 Cells; Animals; Binding, Competitive; CHO Cells; Colforsin; Cricetinae; Cyclic AMP; Discrimination Learning; Drug Evaluation, Preclinical; Fluorine; Hallucinogens; Humans; Hydrolysis; Mice; Phosphatidylinositols; Radioligand Assay; Rats; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Receptor Agonists; Structure-Activity Relationship; Tryptamines | 2000 |
A novel fluorinated tryptamine with highly potent serotonin 5-HT1A receptor agonist properties.
Topics: Fluorides; Indoles; Pyrrolidines; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Receptor Agonists; Tryptamines | 2001 |
Molecular cloning and pharmacological characterization of the guinea pig 5-HT1E receptor.
Topics: Amino Acid Sequence; Animals; Base Sequence; Brain; Chickens; Cloning, Molecular; Cricetinae; Dose-Response Relationship, Drug; Gerbillinae; Guinea Pigs; Haplorhini; Humans; Molecular Sequence Data; Protein Binding; Rabbits; Receptors, Serotonin; Serotonin Agents; Swine | 2004 |
cis-4-(Piperazin-1-yl)-5,6,7a,8,9,10,11,11a-octahydrobenzofuro[2,3-h]quinazolin-2-amine (A-987306), a new histamine H4R antagonist that blocks pain responses against carrageenan-induced hyperalgesia.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzofurans; Carrageenan; Disease Models, Animal; Drug Design; Drug Evaluation, Preclinical; Humans; Hyperalgesia; Ligands; Mice; Molecular Structure; Pain; Peritonitis; Quinazolines; Rats; Receptors, G-Protein-Coupled; Receptors, Histamine; Receptors, Histamine H4; Stereoisomerism; Structure-Activity Relationship | 2008 |
Tryptophan 2,3-dioxygenase (TDO) inhibitors. 3-(2-(pyridyl)ethenyl)indoles as potential anticancer immunomodulators.
Topics: Animals; Antineoplastic Agents; Biological Availability; Cell Line; Drug Design; Enzyme Inhibitors; Humans; Immunologic Factors; Indoles; Kinetics; Mice; Neoplasms; Structure-Activity Relationship; Tryptophan Oxygenase | 2011 |
Synthesis and structure-activity relationship studies in serotonin 5-HT(1A) receptor agonists based on fused pyrrolidone scaffolds.
Topics: Animals; Area Under Curve; Humans; Intestinal Absorption; Ligands; Male; Metabolic Clearance Rate; Models, Chemical; Models, Molecular; Molecular Structure; Protein Binding; Protein Structure, Tertiary; Pyrrolidinones; Radioligand Assay; Receptor, Serotonin, 5-HT1A; Receptors, Serotonin, 5-HT3; Serotonin 5-HT1 Receptor Agonists; Structure-Activity Relationship | 2013 |
Synthesis and biological evaluation of 2-(5-methyl-4-phenyl-2-oxopyrrolidin-1-yl)-acetamide stereoisomers as novel positive allosteric modulators of sigma-1 receptor.
Topics: Acetamides; Allosteric Regulation; Animals; Rats; Rats, Wistar; Receptors, sigma; Sigma-1 Receptor; Stereoisomerism; Structure-Activity Relationship | 2013 |
Design, physico-chemical properties and biological evaluation of some new N-[(phenoxy)alkyl]- and N-{2-[2-(phenoxy)ethoxy]ethyl}aminoalkanols as anticonvulsant agents.
Topics: Amino Alcohols; Animals; Anticonvulsants; Chemistry, Physical; Dose-Response Relationship, Drug; Drug Design; Epilepsy; Male; Mice; Microsomes, Liver; Molecular Structure; Pilocarpine | 2016 |
Structure-anticonvulsant activity studies in the group of (E)-N-cinnamoyl aminoalkanols derivatives monosubstituted in phenyl ring with 4-Cl, 4-CH
Topics: Amino Alcohols; Animals; Anticonvulsants; Crystallography, X-Ray; Disease Models, Animal; Dose-Response Relationship, Drug; Electroshock; Mice; Models, Molecular; Molecular Structure; Rats; Seizures; Structure-Activity Relationship | 2017 |
The 2014 Philip S. Portoghese Medicinal Chemistry Lectureship: The "Phenylalkylaminome" with a Focus on Selected Drugs of Abuse.
Topics: Animals; Central Nervous System Stimulants; Chemistry, Pharmaceutical; Dopamine; Drug Discovery; Hallucinogens; Humans; Illicit Drugs; Norepinephrine; Phenethylamines; Psychotropic Drugs; Receptors, Serotonin; Serotonin | 2017 |
Selective 5-HT1A and 5-HT2 receptor-mediated adrenocorticotropin release in the rat: effect of repeated antidepressant treatments.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenocorticotropic Hormone; Amitriptyline; Amphetamines; Animals; Antidepressive Agents; Lithium; Male; Rats; Rats, Sprague-Dawley; Receptors, Serotonin | 1992 |
5-HT2/5-HT1C receptor-mediated facilitatory action on unit activity of ventral horn cells in rat spinal cord slices.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Action Potentials; Amphetamines; Animals; Anterior Horn Cells; Anti-Anxiety Agents; Electric Stimulation; Isoindoles; Methoxydimethyltryptamines; Piperazines; Pyrimidines; Rats; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Spinal Cord | 1992 |
Neuroendocrine responses to the serotonin2 agonist DOI are differentially modified by three 5-HT1A agonists.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenocorticotropic Hormone; Amphetamines; Animals; Anti-Anxiety Agents; Buspirone; Corticosterone; Male; Neurosecretory Systems; Prolactin; Pyrimidines; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Renin; Serotonin Receptor Agonists | 1992 |
Noradrenergic mediation of spinal antinociception by 5-hydroxytryptamine: characterization of receptor subtypes.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic alpha-Antagonists; Amphetamines; Animals; Desipramine; In Vitro Techniques; Male; Nociceptors; Norepinephrine; Oxidopamine; Piperazines; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Serotonin; Serotonin Receptor Agonists; Spinal Cord | 1992 |
Stimulation of 5-HT1 receptors in the spinal cord changes substance P-induced behaviour.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Analgesia; Animals; Indoles; Injections, Spinal; Male; Mice; Mice, Inbred Strains; Nerve Endings; Neurons; Pain; Piperazines; Quipazine; Receptors, Serotonin; Reference Values; Serotonin; Serotonin Antagonists; Spinal Cord; Stereotyped Behavior; Substance P | 1992 |
A comparison of the effects of the 5-HT1 agonists TFMPP and RU 24969 on feeding following peripheral or medial hypothalamic injection.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Eating; Food Deprivation; Hypothalamus, Middle; Indoles; Male; Microinjections; Piperazines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin Antagonists; Tetrahydronaphthalenes | 1992 |
Role of serotonin receptor subtype in seizures kindled from the feline hippocampus.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Anticonvulsants; Cats; Electric Stimulation; Female; Hallucinogens; Hippocampus; Ketanserin; Kindling, Neurologic; Male; Receptors, Serotonin; Seizures; Tetrahydronaphthalenes | 1992 |
Behaviors induced by 5-hydroxytryptophan in neonatal, preweaning, postweaning, and adult Sprague-Dawley rats.
Topics: 5-Hydroxytryptophan; 8-Hydroxy-2-(di-n-propylamino)tetralin; Aging; Amphetamines; Animals; Animals, Newborn; Behavior, Animal; Female; Pregnancy; Rats; Rats, Sprague-Dawley; Tremor | 1992 |
Diverse actions of 5-hydroxytryptamine on frog spinal dorsal horn neurons in vitro.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Dioxanes; Electric Stimulation; Evoked Potentials; Female; In Vitro Techniques; Ketanserin; Kinetics; Male; Membrane Potentials; Methysergide; Mianserin; Neurons; Rana pipiens; Serotonin; Serotonin Antagonists; Spinal Cord; Spiro Compounds; Synapses; Tetrodotoxin; Tropanes | 1992 |
Electrophysiological analyses of serotonergic actions on neurons in hypothalamic ventromedial nucleus in vitro: receptor subtypes involved and implications for regulation of feeding and lordosis behaviors.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Electrophysiology; Feeding Behavior; Female; In Vitro Techniques; Indoles; Neural Inhibition; Neurons; Piperazines; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Sexual Behavior, Animal; Tropisetron; Ventromedial Hypothalamic Nucleus | 1992 |
Serotonin receptor ontogeny: effects of agonists in 1-day-old rats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aging; Amphetamines; Animals; Animals, Newborn; Female; Indoles; Pregnancy; Rats; Receptors, Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists | 1992 |
The 5-HT2 receptor agonist 1-(2,5-dimethoxy-4-iodophenyl)2-aminopropane increases brain tryptophan levels in the rat.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Brain Chemistry; Dose-Response Relationship, Drug; Male; Piperazines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Tetrahydronaphthalenes; Tryptophan | 1992 |
Benzofuran bioisosteres of hallucinogenic tryptamines.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Benzofurans; Ethylamines; Frontal Lobe; Hallucinogens; Hippocampus; Male; Molecular Structure; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin Antagonists; Structure-Activity Relationship; Tetrahydronaphthalenes; Tryptamines | 1992 |
Pharmacological characterization of serotonin receptor subtypes involved in vasopressin and plasma renin activity responses to serotonin agonists.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Arginine Vasopressin; Blood Pressure; Injections, Intravenous; Male; Piperazines; Radioimmunoassay; Rats; Rats, Inbred Strains; Receptors, Serotonin; Renin; Serotonin Antagonists; Tetrahydronaphthalenes | 1992 |
Different role of 5-HT1A and 5-HT2 receptors in spinal cord in the control of nociceptive responsiveness.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Analgesics; Animals; Behavior, Animal; Injections, Spinal; Male; Mice; Nociceptors; Receptors, Serotonin; Serotonin Antagonists; Substance P; Tetrahydronaphthalenes | 1991 |
Analgesic effects of serotonin and receptor-selective serotonin agonists in the rat spinal cord.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Analgesics; Animals; Biguanides; Injections, Spinal; Male; Pain Measurement; Piperazines; Rats; Rats, Inbred Strains; Reaction Time; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Spinal Cord; Tetrahydronaphthalenes | 1991 |
Release of endogenous aspartate from rat cerebellum slices and synaptosomes: inhibition mediated by a 5-HT2 receptor and by a 5-HT1 receptor of a possibly novel subtype.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Aspartic Acid; Calcium; Cerebellum; Ketanserin; Male; Methiothepin; Potassium; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Synaptosomes; Tetrahydronaphthalenes | 1991 |
Characterization of the 5-HT receptor subtypes involved in the motor behaviours produced by intrathecal administration of 5-HT agonists in rats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Clorgyline; Fluoxetine; Injections, Spinal; Ketanserin; Male; Motor Activity; Muscle Contraction; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin; Tetrahydronaphthalenes | 1991 |
Species differences in the distribution of central 5-HT1 binding sites: a comparative autoradiographic study between rat and guinea pig.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Autoradiography; Brain; Guinea Pigs; Ligands; Male; Piperazines; Pyrimidines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin Antagonists; Species Specificity; Tetrahydronaphthalenes | 1991 |
The relation of central 5-HT1A and 5-HT2 receptors: low dose agonist-induced selective tolerance in the rat.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Behavior, Animal; Body Temperature Regulation; Brain Chemistry; Drug Tolerance; Injections, Intraperitoneal; Male; Motor Activity; Myoclonus; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin Antagonists; Tetrahydronaphthalenes | 1991 |
Effects of repeated treatment with 1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane (DOI) on the autoregulatory control of dorsal raphe 5-HT neuronal firing and cortical 5-HT release.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Analysis of Variance; Animals; Cerebral Cortex; Drug Administration Schedule; Electrophysiology; Male; Motor Activity; Neurons; Raphe Nuclei; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Tetrahydronaphthalenes | 1991 |
The effects of serotonergic compounds on evoked responses in the dentate gyrus and CA1 region of the hippocampal formation of the rat.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Electric Stimulation; Evoked Potentials; Hippocampus; In Vitro Techniques; Ketanserin; Male; Methysergide; Rats; Rats, Inbred Strains; Receptors, Serotonin; Tetrahydronaphthalenes | 1991 |
Attenuation of 5-HT1A and 5-HT2 but not 5-HT1C receptor mediated behaviour in rats following chronic treatment with 5-HT receptor agonists, antagonists or anti-depressants.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Antidepressive Agents; Behavior, Animal; Bridged Bicyclo Compounds; Bridged-Ring Compounds; Male; Mianserin; Penile Erection; Pyrazines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin Antagonists; Tetrahydronaphthalenes; Tranylcypromine | 1991 |
Effect of isolation rearing on 5-HT agonist-induced responses in the rat.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Behavior, Animal; Male; Methoxydimethyltryptamines; Motor Activity; Muscle Contraction; Rats; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Social Isolation; Tetrahydronaphthalenes | 1991 |
5-HT2 presynaptic receptors mediate inhibition of glutamate release from cerebellar mossy fibre terminals.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Calcium; Cerebellum; Glutamates; In Vitro Techniques; Ketanserin; Male; Microscopy, Electron; Nerve Endings; Rats; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Synaptosomes; Tetrahydronaphthalenes; Tetrodotoxin | 1991 |
Electrophysiological characterization of 5-hydroxytryptamine2 receptors in the rat medial prefrontal cortex.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; DOM 2,5-Dimethoxy-4-Methylamphetamine; Ergolines; Frontal Lobe; Ketanserin; Magnesium; Male; Pyridazines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin Antagonists; Sodium Glutamate; Tetrahydronaphthalenes | 1990 |
Characterization of the effects of activation of ventral medullary serotonin receptor subtypes on cardiovascular activity and respiratory motor outflow to the diaphragm and larynx.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Blood Pressure; Cats; Female; Heart Rate; Laryngeal Nerves; Male; Medulla Oblongata; Phrenic Nerve; Piperazines; Receptors, Serotonin; Recurrent Laryngeal Nerve; Respiration; Tetrahydronaphthalenes | 1990 |
5HT-2 mediation of acute behavioral effects of hallucinogens in rats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Behavior, Animal; DOM 2,5-Dimethoxy-4-Methylamphetamine; Dose-Response Relationship, Drug; Hallucinogens; Ketanserin; Male; Mescaline; Piperidines; Quipazine; Rats; Rats, Inbred Strains; Ritanserin; Serotonin; Tetrahydronaphthalenes | 1990 |
The functional significance of neonatal 5,7-dihydroxytryptamine lesions in the rat: response to selective 5-HT1A and 5-HT2,1C agonists.
Topics: 5,7-Dihydroxytryptamine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Animals, Newborn; Behavior, Animal; Brain; Dihydroxytryptamines; Naphthalenes; Rats; Rats, Inbred Strains; Receptors, Serotonin; Tetrahydronaphthalenes | 1990 |
5-HT1A, 5-HT1B and 5-HT2 receptor agonists induce differential behavioral responses in preweanling rat pups.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Animals, Newborn; Behavior, Animal; Eating; Female; Grooming; Hindlimb; Male; Milk; Motor Activity; Piperazines; Pyrimidines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Tetrahydronaphthalenes | 1990 |
Do functional relationships exist between 5-HT1A and 5-HT2 receptors?
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Behavior, Animal; Dose-Response Relationship, Drug; Injections, Intravenous; Ketanserin; Male; Methoxydimethyltryptamines; Mice; Mice, Inbred ICR; Piperazines; Receptors, Serotonin; Serotonin Antagonists; Spiperone; Stereoisomerism; Tetrahydronaphthalenes | 1990 |
Behavioral mechanisms for the anorectic action of the serotonin (5-HT) uptake inhibitor sertraline in rats: comparison with directly acting 5-HT agonists.
Topics: 1-Naphthylamine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Appetite; Eating; Feeding Behavior; Indoles; Male; Piperazines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Satiation; Sertraline; Tetrahydronaphthalenes | 1990 |
Receptor subtypes mediating facilitation by serotonin of excitability of spinal motoneurons.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; In Vitro Techniques; Injections, Intravenous; Iontophoresis; Ketanserin; Male; Methysergide; Microelectrodes; Motor Neurons; Piperidines; Prazosin; Quipazine; Rats; Rats, Inbred Strains; Receptors, Serotonin; Ritanserin; Serotonin; Serotonin Antagonists; Spinal Cord; Tetrahydronaphthalenes | 1990 |
Behavioural evidence for functional interactions between 5-HT-receptor subtypes in rats and mice.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Behavior, Animal; Body Temperature; Male; Mice; Mice, Inbred ICR; Motor Activity; Piperazines; Pyrazines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin Antagonists; Tetrahydronaphthalenes | 1990 |
5-Hydroxytryptamine responses in neonate rat motoneurones in vitro.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Action Potentials; Amphetamines; Animals; Animals, Newborn; Calcium; In Vitro Techniques; Magnesium; Motor Neurons; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Spinal Cord; Tetrahydronaphthalenes; Tetrodotoxin; Time Factors | 1990 |
Mechanisms of serotonin receptor agonist-induced activation of the hypothalamic-pituitary-adrenal axis in the rat.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenocorticotropic Hormone; Amphetamines; Animals; Biomechanical Phenomena; Corticotropin-Releasing Hormone; Dexamethasone; Hypothalamo-Hypophyseal System; Immune Sera; Male; Naphthalenes; Piperazines; Pituitary Gland; Pituitary-Adrenal System; Rats; Receptors, Serotonin; Tetrahydronaphthalenes | 1990 |
Facilitation of 8-OHDPAT-induced forepaw treading of rats by the 5-HT2 agonist DOI.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Alprenolol; Amphetamines; Animals; Behavior, Animal; Cerebral Cortex; Injections, Subcutaneous; Ketanserin; Male; Naphthalenes; Piperidines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Ritanserin; Tetrahydronaphthalenes | 1989 |
Selective cross-tolerance to 5-HT1A and 5-HT2 receptor-mediated temperature and corticosterone responses.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Body Temperature Regulation; Corticosterone; Dose-Response Relationship, Drug; Drug Interactions; Male; Methoxydimethyltryptamines; Naphthalenes; Pyrazines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Tetrahydronaphthalenes; Tryptamines | 1989 |
Serotonin agonists cause parallel activation of the sympathoadrenomedullary system and the hypothalamo-pituitary-adrenocortical axis in conscious rats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenal Cortex; Adrenal Medulla; Adrenocorticotropic Hormone; Amphetamines; Animals; Corticosterone; Epinephrine; Hypothalamo-Hypophyseal System; Kinetics; Male; Naphthalenes; Norepinephrine; Piperazines; Pituitary-Adrenal System; Rats; Rats, Inbred Strains; Reference Values; Serotonin; Sympathetic Nervous System; Tetrahydronaphthalenes | 1989 |
Discriminative stimulus properties of the serotonergic agent 1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane (DOI).
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Discrimination Learning; Dose-Response Relationship, Drug; Isomerism; Male; Piperazines; Rats; Rats, Inbred Strains; Serotonin; Tetrahydronaphthalenes | 1986 |
Effects of serotonin1 and serotonin2 receptor agonists and antagonists on blood pressure, heart rate and sympathetic nerve activity.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Blood Pressure; Cats; Heart Rate; Piperazines; Pyrazines; Receptors, Serotonin; Serotonin Antagonists; Sympathetic Nervous System; Tetrahydronaphthalenes | 1987 |
Modulation of rat neocortical high-voltage spindle activity by 5-HT1/5-HT2 receptor subtype specific drugs.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Analysis of Variance; Animals; Cerebral Cortex; Electroencephalography; Infusions, Parenteral; Ketanserin; Male; Methiothepin; Methysergide; Neural Pathways; Rats; Rats, Wistar; Receptors, Serotonin; Ritanserin; Thalamus | 1995 |
Evidence for alterations in presynaptic serotonergic function during withdrawal from chronic cocaine in rats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Cocaine; Corticosterone; Fenfluramine; Humans; Male; Neurosecretory Systems; Presynaptic Terminals; Rats; Rats, Sprague-Dawley; Serotonin; Serotonin Agents; Substance Withdrawal Syndrome | 1995 |
Role of 5-HT receptor subtypes in the modulation of dorsal periaqueductal gray generated aversion.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Avoidance Learning; Dose-Response Relationship, Drug; Electric Stimulation; Injections; Male; Periaqueductal Gray; Rats; Rats, Wistar; Receptors, Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists | 1995 |
Age-related behavioural, neurochemical and radioligand binding changes in the central 5-HT system of Sprague-Dawley rats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aging; Amphetamines; Animals; Behavior, Animal; Binding, Competitive; Brain Chemistry; Dose-Response Relationship, Drug; Guanosine Triphosphate; Hydroxyindoleacetic Acid; Ketanserin; Male; Radioligand Assay; Rats; Rats, Sprague-Dawley; Serotonin; Serotonin Receptor Agonists | 1993 |
Effects of intracerebroventricular administration of 5-HT receptor agonists on the maternal aggression of rats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aggression; Amphetamines; Analysis of Variance; Animals; Female; Injections, Intraventricular; Maternal Behavior; Piperazines; Rats; Rats, Wistar; Serotonin Receptor Agonists | 1994 |
Agonist activation of 5-HT1A receptors in the median raphe nucleus and female rat lordosis behavior.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Female; Proestrus; Raphe Nuclei; Rats; Rats, Inbred Strains; Serotonin; Serotonin Receptor Agonists; Sexual Behavior, Animal; Ventromedial Hypothalamic Nucleus | 1994 |
(1-(2,5-dimethoxy-4 iodophenyl)-2-aminopropane)-induced head-twitches in the rat are mediated by 5-hydroxytryptamine (5-HT) 2A receptors: modulation by novel 5-HT2A/2C antagonists, D1 antagonists and 5-HT1A agonists.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Behavior, Animal; Benzazepines; Dopamine Antagonists; Male; Piperazines; Quipazine; Rats; Rats, Wistar; Receptors, Adrenergic; Receptors, Dopamine D1; Receptors, Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists | 1995 |
5-HT1A and muscarinic acetylcholine receptors jointly regulate passive avoidance behavior.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Avoidance Learning; Behavior, Animal; Choline O-Acetyltransferase; Drug Interactions; Ketanserin; Male; Motor Activity; Muscarinic Agonists; Pain Measurement; Pain Threshold; Rats; Rats, Wistar; Receptors, Muscarinic; Receptors, Serotonin; Scopolamine; Septal Nuclei; Serotonin Receptor Agonists | 1994 |
Functional assessment of the 5-HT 1A-, 1B-, 2A/2C-, and 3-receptor subtypes on food intake and metabolic rate in rats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Analysis of Variance; Animals; Biguanides; Circadian Rhythm; Darkness; Energy Metabolism; Feeding Behavior; Indoles; Light; Male; Oxygen Consumption; Rats; Rats, Wistar; Receptors, Serotonin; Serotonin Receptor Agonists; Time Factors | 1995 |
Cross-tolerance studies of serotonin receptors involved in behavioral effects of LSD in rats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Behavior, Animal; Dose-Response Relationship, Drug; Drug Tolerance; Lysergic Acid Diethylamide; Male; Motor Activity; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Serotonin Receptor Agonists | 1994 |
Effect of pertussis toxin on the response of rat medial prefrontal cortex cells to the iontophoresis of serotonin receptor agonists.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Action Potentials; Amphetamines; Animals; Frontal Lobe; gamma-Aminobutyric Acid; GTP-Binding Proteins; Iontophoresis; Neurons; Pertussis Toxin; Rats; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin; Serotonin Receptor Agonists; Signal Transduction; Virulence Factors, Bordetella | 1994 |
The role of serotonin receptor subtypes in the behavioural effects of neuroleptic drugs. A paw test study in rats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Antipsychotic Agents; Basal Ganglia Diseases; Behavior, Animal; Clozapine; Haloperidol; Ketanserin; Male; Rats; Rats, Wistar; Receptors, Serotonin; Ritanserin; Serotonin Antagonists; Serotonin Receptor Agonists | 1994 |
5-HT1A receptor-mediated inhibition of N-type calcium current in acutely isolated ventromedial hypothalamic neuronal cells.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Calcium Channel Blockers; Calcium Channels; Cells, Cultured; Ion Channel Gating; Neurons; omega-Conotoxin GVIA; Peptides; Rats; Receptors, Serotonin; Serotonin; Serotonin Receptor Agonists; Ventromedial Hypothalamic Nucleus | 1994 |
Comparison of stimulus properties of fluoxetine and 5-HT receptor agonists in a conditioned taste aversion procedure.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Analysis of Variance; Animals; Avoidance Learning; Conditioning, Classical; Fluoxetine; Male; Mice; Paroxetine; Pyrazines; Serotonin Receptor Agonists; Taste | 1994 |
The induction of serotonin3-like receptor supersensitivity and dopamine receptor subsensitivity in the rat medial prefrontal cortex after the intraventricular administration of the neurotoxin 5,7-dihydroxytryptamine: a microiontophoretic study.
Topics: 5,7-Dihydroxytryptamine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Cerebral Ventricles; Dose-Response Relationship, Drug; Injections, Intraventricular; Iontophoresis; Male; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Receptors, Dopamine; Serotonin; Serotonin Receptor Agonists | 1994 |
Antidepressant treatment and limbic serotonergic mechanisms regulating rat locomotor activity.
Topics: 5,7-Dihydroxytryptamine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Antidepressive Agents; Biogenic Monoamines; Brain Chemistry; Electroshock; Limbic System; Male; Microinjections; Motor Activity; Nucleus Accumbens; Rats; Rats, Wistar; Serotonin; Serotonin Receptor Agonists | 1994 |
The effects of alpha 2-adrenoceptor antagonists on the inhibition of 1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane (DOI)-induced head shakes by 5-HT1A receptor agonists in the mouse.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Amphetamines; Animals; Brain Chemistry; Buspirone; Fenclonine; Male; Mice; Mice, Inbred Strains; Serotonin; Serotonin Receptor Agonists; Stereotyped Behavior | 1993 |
Hypothalamic infusion of the 5-HT2/1C agonist, DOI, prevents the inhibitory actions of the 5-HT1A agonist, 8-OH-DPAT, on lordosis behavior.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Female; Injections; Injections, Intraperitoneal; Posture; Proestrus; Rats; Rats, Inbred F344; Serotonin Receptor Agonists; Sexual Behavior, Animal; Ventromedial Hypothalamic Nucleus | 1994 |
Drug discrimination and receptor binding studies of N-isopropyl lysergamide derivatives.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Binding, Competitive; Conditioning, Operant; Discrimination, Psychological; Hallucinogens; Iodine Radioisotopes; Ketanserin; Lysergic Acid Diethylamide; Male; Models, Molecular; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Reinforcement Schedule | 1994 |
The effects of long-term treatment with the 5-HT1A receptor agonist 8-OH-DPAT and the 5-HT2/1C receptor agonist DOI in the neonatal rat.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Animals, Newborn; Dose-Response Relationship, Drug; Female; Ketanserin; Pregnancy; Rats; Rats, Sprague-Dawley; Serotonin Antagonists; Serotonin Receptor Agonists; Vocalization, Animal | 1993 |
Lithium enhances 5-HT2A receptor-mediated c-fos expression in rat cerebral cortex.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Cerebral Cortex; Gene Expression; Genes, fos; Immunohistochemistry; Lithium; Male; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Serotonin Receptor Agonists | 1993 |
Serotonin-mediated 5-HT2 receptor gene regulation in rat myometrial smooth muscle cells.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Biguanides; Cells, Cultured; Cycloheximide; Female; Gene Expression Regulation; Ketanserin; Medroxyprogesterone Acetate; Myometrium; Piperazines; Quipazine; Rats; Receptors, Serotonin; RNA, Messenger; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Spiperone; Sulpiride; Transcription, Genetic; Up-Regulation | 1993 |
Stimulation of 5-HT1A and 5-HT2/5-HT1C receptors induce oxytocin release in the male rat.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Buspirone; Male; Oxytocin; Piperazines; Pyrimidines; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Ritanserin; Serotonin Antagonists; Serotonin Receptor Agonists | 1993 |
Autoradiographic localization of 5-hydroxytryptamine1A, 5-hydroxytryptamine1B and 5-hydroxytryptamine1C/2 binding sites in the rat spinal cord.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Iodocyanopindolol; Male; Motor Neurons; Pindolol; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Serotonin; Spinal Cord | 1993 |
Effect of selective serotonin agonists on basal, corticotrophin-releasing hormone- and vasopressin-induced ACTH release in vitro from rat pituitary cells.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenocorticotropic Hormone; Amphetamines; Animals; Arginine Vasopressin; Cells, Cultured; Corticotropin-Releasing Hormone; Male; Piperazines; Pituitary Gland, Anterior; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Serotonin Receptor Agonists; Stimulation, Chemical | 1993 |
Chronic, combined treatment with desipramine and mianserin: enhanced 5-HT1A receptor function and altered 5-HT1A/5-HT2 receptor interaction in rats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Behavior, Animal; Body Temperature; Body Weight; Desipramine; Drinking Behavior; Hippocampus; Male; Mianserin; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, Serotonin; Serotonin Receptor Agonists; Spinal Cord | 1993 |
5-HT-dependent myoclonus in guinea pigs: mediation through 5-HT1A-5-HT2 receptor interaction.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Behavior, Animal; Guinea Pigs; Male; Myoclonus; Receptors, Serotonin; Ritanserin; Serotonin; Serotonin Receptor Agonists | 1993 |
Restoration of extensor excitability in the acute spinal cat by the 5-HT2 agonist DOI.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Cats; Decerebrate State; Electromyography; In Vitro Techniques; Quinoxalines; Reflex, Stretch; Serotonin; Serotonin Receptor Agonists | 1996 |
Neonatal organizational effects of the 5-HT2 and 5-HT1A subsystems on adult behavior in the rat.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Animals, Newborn; Anxiety; Behavior, Animal; Exploratory Behavior; Female; Male; Motivation; Motor Activity; Orchiectomy; Rats; Rats, Wistar; Receptors, Serotonin; Ritanserin; Serotonin Antagonists; Serotonin Receptor Agonists; Sex Characteristics; Sexual Behavior, Animal; Testosterone | 1996 |
Long-lasting synaptic facilitation induced by serotonin in superficial dorsal horn neurones of the rat spinal cord.
Topics: 1-Methyl-3-isobutylxanthine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Colforsin; Electrophysiology; Naphthalenes; Neurons; Patch-Clamp Techniques; Phorbol Esters; Protein Kinase C; Rats; Rats, Wistar; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin; Serotonin Receptor Agonists; Spinal Cord; Synapses; Tetrodotoxin | 1996 |
Genomic responses to 5-HT1A or 5-HT2A/2C receptor activation is differentially regulated in four regions of rat brain.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Blotting, Northern; Brain; Cerebellum; Cerebral Cortex; Corpus Striatum; DNA Probes; Gene Expression; Gene Expression Regulation; Genes, fos; Genes, Immediate-Early; Hippocampus; Ketanserin; Male; Piperazines; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; RNA, Messenger; Serotonin Antagonists; Serotonin Receptor Agonists | 1996 |
Modulation of 5-HT receptor subtype-mediated behaviours by corticosterone.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Behavior, Animal; Corticosterone; Locomotion; Male; Pyrazines; Rats; Rats, Wistar; Receptors, Serotonin; Serotonin Receptor Agonists | 1996 |
Preprotachykinin and preproenkephalin mRNA expression within striatal subregions in response to altered serotonin transmission.
Topics: 5,7-Dihydroxytryptamine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Amygdala; Animals; Corpus Striatum; Enkephalins; Fenclonine; Male; Nerve Endings; Organ Specificity; Prosencephalon; Protein Precursors; Rats; Rats, Sprague-Dawley; RNA, Messenger; Serotonin; Serotonin Agents; Tachykinins; Time Factors; Transcription, Genetic | 1996 |
Effects of 8-OH-DPAT, a 5-HT1A receptor agonist, and DOI, a 5-HT2A/2C agonist, on monosynaptic transmission in spinalized rats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Decerebrate State; Dose-Response Relationship, Drug; Male; Motor Neurons; Rats; Rats, Wistar; Reflex, Monosynaptic; Serotonin Receptor Agonists; Synaptic Transmission | 1996 |
Effects of 5-HT agonists, selective for different receptor subtypes, on oxytocin, CCK, gastrin and somatostatin plasma levels in the rat.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Cholecystokinin; Gastrins; Male; Neuropeptides; Oxytocin; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Serotonin Receptor Agonists; Somatostatin | 1996 |
Role of serotonin receptor subtypes in the development of amygdaloid kindling in rats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Amygdala; Animals; Electric Stimulation; Kindling, Neurologic; Male; Rats; Rats, Wistar; Receptors, Serotonin; Serotonin Receptor Agonists | 1997 |
5-HT2A receptor-mediated regulation of brain-derived neurotrophic factor mRNA in the hippocampus and the neocortex.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenalectomy; Amphetamines; Analysis of Variance; Animals; Brain-Derived Neurotrophic Factor; Cerebral Cortex; Dentate Gyrus; Hallucinogens; Hippocampus; Male; Models, Neurological; Neurons; Organ Specificity; Parietal Lobe; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; RNA, Messenger; Serotonin Receptor Agonists; Transcription, Genetic | 1997 |
Hypothyroid-induced changes in autonomic control have a central serotonergic component.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Atropine; Autonomic Nervous System; Blood Pressure; Body Temperature; Brain; Cardiovascular System; Heart Rate; Hypothyroidism; Injections, Intraventricular; Male; Rats; Rats, Sprague-Dawley; Reference Values; Serotonin; Serotonin Receptor Agonists | 1997 |
5-HT1A and 5-HT2A receptor affinity and functional profile of some N-[3-(4-aryl-1-piperazinyl)propyl] derivatives of indolin-2(1H)-one, quinolin-2(1 H)-one and isoquinolin-1(2H)-one. Part 30: Structure-activity relationship studies of CNS agents.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Behavior, Animal; Binding, Competitive; Chemical Phenomena; Chemistry, Physical; Hippocampus; In Vitro Techniques; Indoles; Isoquinolines; Ketanserin; Kinetics; Male; Mice; Piperazines; Quinolones; Radioligand Assay; Rats; Rats, Wistar; Receptors, Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists | 1997 |
Pharmacological characterization of in vivo properties of putative mixed 5-HT1A agonist/5-HT(2A/2C) antagonist anxiolytics. II. Drug discrimination and behavioral observation studies in rats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Anti-Anxiety Agents; Behavior, Animal; Benzopyrans; Discrimination, Psychological; Ketanserin; Lysergic Acid Diethylamide; Male; Nicotinic Acids; Piperazines; Piperidines; Protein Binding; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Ritanserin; Serotonin Antagonists; Serotonin Receptor Agonists | 1997 |
Effects of corticosterone on 5-HT1A and 5-HT2 receptor binding and on the receptor-mediated behavioral responses of rats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Anti-Inflammatory Agents; Behavior, Animal; Corticosterone; Frontal Lobe; Hippocampus; Ketanserin; Male; Radioligand Assay; Rats; Rats, Wistar; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Antagonists; Serotonin Receptor Agonists; Tremor | 1997 |
Indirect in vivo 5-HT1A-agonistic effects of the new antidepressant mirtazapine.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Antidepressive Agents, Tricyclic; Behavior, Animal; Conditioning, Operant; Fluoxetine; Male; Mianserin; Mice; Mice, Inbred ICR; Mirtazapine; Pyrazines; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Selective Serotonin Reuptake Inhibitors; Serotonin Receptor Agonists; Taste | 1997 |
Modulation of the behavioral effects of 8-OH-DPAT by estrogen and DOI.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Behavior, Animal; Body Temperature; Estrogens; Female; Gonadal Steroid Hormones; Ovariectomy; Posture; Pregnancy; Rats; Rats, Inbred F344; Serotonin Receptor Agonists; Sexual Behavior, Animal | 1997 |
Serotonin 5-HT2C agonists selectively inhibit morphine-induced dopamine efflux in the nucleus accumbens.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Cocaine; Dopamine; Dopamine Uptake Inhibitors; Male; Microdialysis; Morphine; Narcotic Antagonists; Nucleus Accumbens; Piperazines; Pyrazines; Rats; Rats, Sprague-Dawley; Serotonin Antagonists; Serotonin Receptor Agonists | 1998 |
Effects of the serotonin agonists 8-OH-DPAT, buspirone, and DOI on water maze performance.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Buspirone; Male; Maze Learning; Rats; Rats, Sprague-Dawley; Serotonin Receptor Agonists | 1998 |
Differential effects of serotonin (5-HT) lesions and synthesis blockade on neuropeptide-Y immunoreactivity and 5-HT1A, 5-HT1B/1D and 5-HT2A/2C receptor binding sites in the rat cerebral cortex.
Topics: 3,4-Dihydroxyphenylacetic Acid; 5,7-Dihydroxytryptamine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Binding, Competitive; Cerebral Cortex; Dipeptides; Dopamine; Female; Fenclonine; Iodine Radioisotopes; Neuronal Plasticity; Neuropeptide Y; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT1D; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin; Serotonin Agents; Tritium | 1998 |
Evidence for an involvement of 5-HT1B receptors in the inhibition of male rat ejaculatory behavior produced by 5-HTP.
Topics: 5-Hydroxytryptophan; 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Ejaculation; Female; Male; Piperazines; Pyridines; Rats; Rats, Wistar; Receptors, Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Sexual Behavior, Animal | 1998 |
5-HT1A receptor agonist (8-OH-DPAT) and 5-HT2 receptor agonist (DOI) disrupt the non-cognitive performance of rats in a working memory task.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Brain; Conditioning, Operant; Dose-Response Relationship, Drug; Hydroxyindoleacetic Acid; Male; Mental Recall; Norepinephrine; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Receptor Agonists | 1998 |
Effect of acute administration of various 5-HT receptor agonists on focal hippocampal seizures in freely moving rats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Behavior, Animal; Electric Stimulation; Electrodes, Implanted; Electroencephalography; Epilepsy, Complex Partial; Fluoxetine; Hippocampus; Kindling, Neurologic; Male; Piperidines; Rats; Rats, Wistar; Selective Serotonin Reuptake Inhibitors; Serotonin Receptor Agonists | 1998 |
Functional integration among 5-hydroxytryptamine receptor families in the control of female rat sexual behavior.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Biguanides; Drug Combinations; Female; Indoles; Ovariectomy; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Sexual Behavior, Animal; Tropisetron | 1998 |
Alterations in serotonergic responsiveness during cocaine withdrawal in rats: similarities to major depression in humans.
Topics: 5-Hydroxytryptophan; 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Behavior, Animal; Cocaine; Depressive Disorder; Dopamine Uptake Inhibitors; Feeding Behavior; Fenfluramine; Male; Prolactin; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Receptor Agonists; Substance Withdrawal Syndrome | 1998 |
Modification of haloperidol-induced pattern of c-fos expression by serotonin agonists.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Antipsychotic Agents; Clozapine; Haloperidol; Male; Prosencephalon; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Receptor Agonists | 1998 |
Interactive effects of cholecystokinin-8S and serotonin on spontaneously active neurons in ventromedial hypothalamic slices.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Postsynaptic Potentials; Female; In Vitro Techniques; Male; Neurons; Oligopeptides; Rats; Rats, Wistar; Receptors, Cholecystokinin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Sincalide; Ventromedial Hypothalamic Nucleus | 1998 |
Evidence for a functional interaction between 5-HT1A and 5-HT2 receptors in rats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Male; Motor Activity; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Receptors, Serotonin, 5-HT1 | 1998 |
Long-term sequential determination of behavioral ontogeny of 5-HT1A and 5-HT2 receptor functions in the rat.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Body Temperature; Female; Head Movements; Hypothermia; Male; Muscle Contraction; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Receptor Agonists; Serotonin Syndrome | 1999 |
The behavior of spontaneously hypertensive and Wistar Kyoto rats under a paced fixed consecutive number schedule of reinforcement.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Chlordiazepoxide; Conditioning, Operant; Dextroamphetamine; Haloperidol; Hypertension; Imipramine; Piperazines; Psychotropic Drugs; Pyridines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Reinforcement Schedule; Species Specificity | 1999 |
Serotonin induces four pharmacologically separable contractile responses in the pharynx of the leech Hirudo medicinalis.
Topics: 5-Methoxytryptamine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Dose-Response Relationship, Drug; Electric Stimulation; In Vitro Techniques; Leeches; Muscle Contraction; Pharynx; Piperazines; Serotonin; Serotonin Receptor Agonists | 1999 |
N-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline studies on the role of 5-HT1A and 5-HT2 receptors in mediating foot-shock-induced ultrasonic vocalisation in adult rats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Benzazepines; Drug Interactions; Male; Piperazines; Pyridines; Quinolines; Rats; Rats, Wistar; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Antagonists; Serotonin Receptor Agonists; Ultrasonics; Vocalization, Animal | 1999 |
Effect of reserpine on behavioural responses to agonists at 5-HT1A, 5-HT1B, 5-HT2A, and 5-HT2C receptor subtypes.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Anxiety; Behavior, Animal; Body Temperature Regulation; Feeding Behavior; Male; Motor Activity; Pain Measurement; Piperazines; Posture; Rats; Rats, Sprague-Dawley; Reserpine; Serotonin Receptor Agonists | 1999 |
The pharmacology of impulsive behaviour in rats VI: the effects of ethanol and selective serotonergic drugs on response choice with varying delays of reinforcement.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Central Nervous System Depressants; Ethanol; Impulsive Behavior; Male; Rats; Rats, Sprague-Dawley; Reinforcement Schedule; Serotonin Antagonists; Serotonin Receptor Agonists | 1999 |
Receptors and neurotransmitters involved in the dual modulation of prolactin release by the serotoninergic system in pregnant and lactating rats.
Topics: 5-Hydroxytryptophan; 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Amphetamines; Analysis of Variance; Animals; Brain Chemistry; Dopamine; Female; Fenclonine; Fenfluramine; Gestational Age; Ketanserin; Metoprolol; Norepinephrine; p-Chloroamphetamine; Prazosin; Pregnancy; Pregnancy, Animal; Prolactin; Rats; Rats, Wistar; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Signal Transduction | 1999 |
The serotonin 5-HT2 receptor-phospholipase C system inhibits the induction of long-term potentiation in the rat visual cortex.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Bicuculline; Electrophysiology; Estrenes; GABA Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Long-Term Potentiation; Male; Phosphodiesterase Inhibitors; Piperazines; Pyrrolidinones; Rats; Rats, Wistar; Receptors, GABA-A; Receptors, Serotonin; Ritanserin; Serotonin Antagonists; Serotonin Receptor Agonists; Tropanes; Type C Phospholipases; Visual Cortex | 2000 |
The non-competitive NMDA receptor blocker dizocilpine potentiates serotonergic function.
Topics: 2-Amino-5-phosphonovalerate; 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Benzazepines; Dizocilpine Maleate; Dopamine Antagonists; Excitatory Amino Acid Antagonists; Ketanserin; Male; Motor Activity; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2A; Receptors, Dopamine D1; Receptors, N-Methyl-D-Aspartate; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin; Serotonin Receptor Agonists; Sulpiride | 1999 |
Serotonin suppresses subthreshold and suprathreshold oscillatory activity of rat inferior olivary neurones in vitro.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Action Potentials; Amphetamines; Animals; Cardiovascular Agents; Electric Impedance; Electrophysiology; Ketanserin; Methysergide; Neurons; Olivary Nucleus; Periodicity; Potassium Channels; Potassium Channels, Inwardly Rectifying; Pyrimidines; Rats; Rats, Sprague-Dawley; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists | 2000 |
Blockade of the serotonergic system counteracts the dizocilpine-induced changes in dopaminergic function.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Behavior, Animal; Dizocilpine Maleate; Dopamine; Dopamine Agonists; Excitatory Amino Acid Antagonists; Grooming; Ketanserin; Male; Methysergide; Motor Activity; Quinpirole; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Antagonists; Serotonin Receptor Agonists; Stereotyped Behavior | 2000 |
Serotonergic mechanisms involved in the attentional and vigilance task performance of rats and the palliative action of aniracetam.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Attention; Male; Nootropic Agents; Palliative Care; Psychomotor Performance; Pyrrolidinones; Rats; Rats, Wistar; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Receptor Agonists | 2000 |
Isoteoline, a putative serotonin antagonist, inhibits meta -chlorophenylpiperazine, but not 1-(2, -dimethoxy-4-iodphenyl)-2-aminopropane and 8-hydroxy-2-(di-n-propylamino)-tetraline-induced increase of serum prolactin levels.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Aporphines; Follicle Stimulating Hormone; Luteinizing Hormone; Male; Piperazines; Prolactin; Rats; Rats, Wistar; Serotonin Antagonists | 2000 |
An endogenous serotonergic rhythm acting on 5-HT(2A) receptors may be involved in the diurnal changes in tuberoinfundibular dopaminergic neuronal activity and prolactin secretion in female rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; 5,7-Dihydroxytryptamine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Circadian Rhythm; Dihydroxyphenylalanine; Dopamine; Estrogens; Female; Ketanserin; Nerve Degeneration; Neurons; Ovariectomy; Pituitary Gland; Prolactin; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Serotonin; Serotonin Agents; Serotonin Antagonists; Serotonin Receptor Agonists | 2000 |
Limited participation of 5-HT(1A) and 5-HT(2A/2C) receptors in the clozapine-induced Fos-protein expression in rat forebrain regions.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Antipsychotic Agents; Clozapine; Corticosterone; Immunohistochemistry; Male; Oncogene Proteins v-fos; Prosencephalon; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Receptor Agonists | 2000 |
Chronic administration of the cholesterol reducing drug gemfibrozil fails to alter 5-HT1A and 5-HT2A mediated receptor behaviours in rats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Anticholesteremic Agents; Cholesterol; Gemfibrozil; Male; Motor Activity; Posture; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Receptor Agonists | 2000 |
Antiallodynic effect of intrathecally administered 5-HT(2) agonists in rats with nerve ligation.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Injections, Spinal; Ligation; Male; Pain Threshold; Posterior Horn Cells; Rats; Rats, Wistar; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Spinal Nerves | 2001 |
Manipulation of operant responding for an ethanol-paired conditioned stimulus in the rat by pharmacological alteration of the serotonergic system.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Alcohol Drinking; Amphetamines; Animals; Buspirone; Conditioning, Operant; Dopamine Antagonists; Ethanol; Female; Fenfluramine; Haloperidol; Piperazines; Rats; Rats, Sprague-Dawley; Reinforcement, Psychology; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Agents; Serotonin Receptor Agonists | 2000 |
Differential effects of 5-HT agonists and antagonists on the repeated acquisition and performance of response sequences in monkeys.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aminopyridines; Amphetamines; Animals; Behavior, Animal; Dose-Response Relationship, Drug; Ergolines; Learning; Macaca fascicularis; Macaca mulatta; Piperazines; Pyridines; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Ritanserin; Serotonin Antagonists; Serotonin Receptor Agonists | 2000 |
D-Cycloserine, a positive modulator of NMDA receptors, inhibits serotonergic function.
Topics: 5-Hydroxytryptophan; 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Behavior, Animal; Cycloserine; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Male; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2A; Receptors, N-Methyl-D-Aspartate; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Receptor Agonists | 2000 |
5-HT(2A) and D(2) receptor blockade increases cortical DA release via 5-HT(1A) receptor activation: a possible mechanism of atypical antipsychotic-induced cortical dopamine release.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Antipsychotic Agents; Benzodiazepines; Cerebral Cortex; Chromatography, High Pressure Liquid; Dopamine; Dopamine D2 Receptor Antagonists; Male; Microdialysis; Olanzapine; Piperazines; Pirenzepine; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Risperidone; Selective Serotonin Reuptake Inhibitors; Serotonin Receptor Agonists; Sulpiride | 2001 |
Effects of 5-HT1A and 5-HT2 receptor agonists on the behavioral and neurochemical consequences of repeated nicotine treatment.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Behavior; Brain; Dopamine; Male; Maze Learning; Microdialysis; Motor Activity; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Receptor Agonists; Time Factors | 2001 |
Effects of 5-HT2 and 5-HT3 receptors on the modulation of nociceptive transmission in rat spinal cord according to the formalin test.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Dose-Response Relationship, Drug; Formaldehyde; Injections, Spinal; Male; Nociceptors; Pain; Pain Measurement; Pyridines; Pyrroles; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT1B; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Receptors, Serotonin, 5-HT3; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Spinal Cord; Synaptic Transmission; Tropanes | 2001 |
Characterization of the functional heterologous desensitization of hypothalamic 5-HT(1A) receptors after 5-HT(2A) receptor activation.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenocorticotropic Hormone; Amphetamines; Animals; Binding, Competitive; Dose-Response Relationship, Drug; Fluorobenzenes; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Hypothalamus; Male; Membrane Proteins; Oxytocin; Piperidines; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Antagonists; Serotonin Receptor Agonists | 2001 |
Different effects of 5-HT receptor agonists on operant response in rats under DRL 10-s and DRL 30-s schedules.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Analysis of Variance; Animals; Conditioning, Operant; Dose-Response Relationship, Drug; Male; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, Serotonin; Reinforcement, Psychology; Serotonin Receptor Agonists; Time Factors | 2001 |
Functional and pharmacological characterization of the modulatory role of serotonin on the firing activity of locus coeruleus norepinephrine neurons.
Topics: 5,7-Dihydroxytryptamine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Antagonists; Amphetamines; Animals; Electric Stimulation; Electrophysiology; Fluorobenzenes; Idazoxan; Locus Coeruleus; Male; Neurons; Norepinephrine; Paroxetine; Patch-Clamp Techniques; Piperazines; Piperidines; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Antagonists | 2001 |
Activation of 5-HT(1B) receptors in the nucleus accumbens reduces self-administration of amphetamine on a progressive ratio schedule.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamine; Amphetamines; Animals; Central Nervous System Stimulants; Conditioning, Operant; Dose-Response Relationship, Drug; Food; Male; Nucleus Accumbens; Oxadiazoles; Piperazines; Pyridines; Pyrroles; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1B; Receptors, Serotonin; Reinforcement Schedule; Self Administration; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists | 2002 |
Effects of estrogen on acetylcholine release in frontal cortex of female rats: involvement of serotonergic neuronal systems.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Acetylcholine; Amphetamines; Animals; Cognition; Diestrus; Drug Implants; Estradiol; Estrogens; Female; Fenfluramine; Frontal Lobe; Microdialysis; Nerve Tissue Proteins; Ovariectomy; Proestrus; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin; Serotonin Receptor Agonists | 2002 |
Chronic imipramine enhances 5-HT(1A) and 5-HT(2) receptors-mediated inhibition of panic-like behavior in the rat dorsal periaqueductal gray.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Avoidance Learning; Electric Stimulation; Escape Reaction; Female; Imipramine; Microinjections; Panic; Periaqueductal Gray; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Receptor Agonists | 2002 |
Effects of serotonin (5-hydroxytryptamine, 5-HT) reuptake inhibition plus 5-HT(2A) receptor antagonism on the firing activity of norepinephrine neurons.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Amphetamines; Animals; Clonidine; Electrophysiology; Idazoxan; Male; Morpholines; Neurons; Norepinephrine; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Selective Serotonin Reuptake Inhibitors; Serotonin Antagonists; Serotonin Receptor Agonists | 2002 |
The effects of serotonin agonists on the hypothalamic regulation of sexual receptivity in Syrian hamsters.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Cricetinae; Female; Hypothalamus; Mesocricetus; Microinjections; Piperazines; Serotonin Receptor Agonists; Sexual Behavior, Animal | 2002 |
5-HT1 and 5-HT2 receptor activation reduces N-methyl-D-aspartate (NMDA)-stimulated LH secretion in prepubertal male and female rats.
Topics: 5-Hydroxytryptophan; 8-Hydroxy-2-(di-n-propylamino)tetralin; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Amphetamines; Animals; Biguanides; Excitatory Amino Acid Agonists; Female; Fenclonine; Luteinizing Hormone; Male; N-Methylaspartate; Rats; Rats, Wistar; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Sexual Maturation | 2003 |
Adaptive changes in the reactivity of 5-HT1A and 5-HT2 receptors induced in rat frontal cortex by repeated imipramine and citalopram.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adaptation, Physiological; Administration, Topical; Amphetamines; Animals; Benzamides; Benzimidazoles; Bridged Bicyclo Compounds, Heterocyclic; Citalopram; Cortical Synchronization; Dose-Response Relationship, Drug; Frontal Lobe; Imipramine; Male; Neurons; Piperazines; Pyridines; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT1A; Receptors, Serotonin, 5-HT2 | 2003 |
Serotonin in the dorsal periaqueductal gray modulates inhibitory avoidance and one-way escape behaviors in the elevated T-maze.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Avoidance Learning; Escape Reaction; Injections, Intraventricular; Male; Maze Learning; Periaqueductal Gray; Piperazines; Rats; Rats, Wistar; Receptors, Serotonin; Serotonin; Serotonin Receptor Agonists | 2003 |
Desensitization of 5-HT1A receptors by 5-HT2A receptors in neuroendocrine neurons in vivo.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenocorticotropic Hormone; Amphetamines; Animals; Antibody Specificity; Corticotropin-Releasing Hormone; Fluorobenzenes; Microinjections; Neurons; Neurosecretory Systems; Oxytocin; Paraventricular Hypothalamic Nucleus; Piperidines; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1A; Receptor, Serotonin, 5-HT2A; Serotonin Antagonists; Serotonin Receptor Agonists | 2004 |
Serotonergic stimulation of the rat hypothalamo-pituitary-adrenal axis: interaction between 5-HT1A and 5-HT2A receptors.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Dose-Response Relationship, Drug; Hypothalamo-Hypophyseal System; Male; Pituitary-Adrenal System; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT1A; Receptor, Serotonin, 5-HT2A; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin 5-HT1 Receptor Agonists; Serotonin 5-HT2 Receptor Agonists; Serotonin Receptor Agonists | 2004 |
Benzodiazepine receptor and serotonin 2A receptor modulate the aversive-like effects of nitric oxide in the dorsolateral periaqueductal gray of rats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Electric Stimulation; GABA Agonists; GABA Modulators; Male; Microinjections; Midazolam; Molsidomine; Nitric Oxide; Nitric Oxide Donors; Periaqueductal Gray; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT2A; Receptors, GABA-A; Reinforcement, Psychology; Serotonin Agents; Serotonin Receptor Agonists; Stereotaxic Techniques | 2004 |
Effects of GABA(B), 5-HT(1A), and 5-HT(2) receptor stimulation on activation and inhibition of the rat lateral amygdala following medial geniculate nucleus stimulation in vivo.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Amygdala; Animals; Anxiety; Baclofen; Evoked Potentials; GABA Agonists; Geniculate Bodies; Ketanserin; Male; Neural Pathways; Piperazines; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1A; Receptors, GABA-B; Receptors, Serotonin, 5-HT2; Serotonin Antagonists; Serotonin Receptor Agonists | 2005 |
Involvement of spinal serotonin receptors in the regulation of intraspinal acetylcholine release.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Acetylcholine; Amphetamines; Animals; Biguanides; Citalopram; Dose-Response Relationship, Drug; Ketanserin; Male; Microdialysis; Piperazines; Pyridines; Pyrroles; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Spinal Cord; Time Factors | 2005 |
Evaluation of DOI, 8-OH-DPAT, eticlopride and amphetamine on impulsive responding in a reaction time task in rats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamine; Amphetamines; Animals; Central Nervous System Stimulants; Dopamine Antagonists; Dose-Response Relationship, Drug; Hallucinogens; Impulsive Behavior; Male; Motor Activity; Rats; Reaction Time; Salicylamides; Serotonin Receptor Agonists | 2005 |
Role of serotonin receptors in panic-like behavior induced by nitric oxide in the rat dorsolateral periaqueductal gray: effects of chronic clomipramine treatment.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Analysis of Variance; Animals; Clomipramine; Histological Techniques; Male; Nitric Oxide; Panic; Periaqueductal Gray; Rats; Rats, Wistar; Serotonin Receptor Agonists | 2005 |
Voltage-dependent calcium currents in trigeminal motoneurons of early postnatal rats: modulation by 5-HT receptors.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Analysis of Variance; Animals; Animals, Newborn; Calcium Channel Blockers; Calcium Channels; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Drug Interactions; Electric Stimulation; In Vitro Techniques; Ketanserin; Membrane Potentials; Motor Neurons; Neural Inhibition; Patch-Clamp Techniques; Piperazines; Rats; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Trigeminal Nuclei | 2005 |
alpha(2)-Adrenoceptor involvement in the in vitro inhibitory effect of citalopram on a subpopulation of rat locus coeruleus neurons.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Action Potentials; Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Amphetamines; Animals; Bridged Bicyclo Compounds, Heterocyclic; Brimonidine Tartrate; Citalopram; Dose-Response Relationship, Drug; Duloxetine Hydrochloride; Idazoxan; In Vitro Techniques; Locus Coeruleus; Male; Methiothepin; Naloxone; Narcotic Antagonists; Neurons; Norepinephrine; Oxazines; Piperazines; Piperidines; Pyridines; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Receptors, Opioid, mu; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Thiophenes | 2005 |
Serotonin 5-HT2 receptors induce a long-lasting facilitation of spinal reflexes independent of ionotropic receptor activity.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Analysis of Variance; Animals; Animals, Newborn; Clozapine; Dose-Response Relationship, Radiation; Drug Interactions; Electric Stimulation; Female; Ganglia, Spinal; Immunohistochemistry; In Vitro Techniques; Male; Pyrazines; Rats; Rats, Sprague-Dawley; Reaction Time; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin, 5-HT2; Reflex; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Spinal Cord; Time Factors | 2005 |
Effects of 5-HT1A and 5-HT2A receptor stimulation on temporal differentiation performance in the fixed-interval peak procedure.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Discrimination Learning; Female; Normal Distribution; Rats; Rats, Wistar; Reaction Time; Receptor, Serotonin, 5-HT1A; Receptor, Serotonin, 5-HT2A; Reinforcement Schedule; Serotonin 5-HT1 Receptor Agonists; Serotonin 5-HT2 Receptor Agonists; Serotonin Receptor Agonists; Statistics, Nonparametric; Time Perception | 2006 |
Chronic imipramine treatment sensitizes 5-HT1A and 5-HT 2 A receptors in the dorsal periaqueductal gray matter: evidence from the elevated T-maze test of anxiety.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Antidepressive Agents, Tricyclic; Anxiety; Buspirone; Imipramine; Male; Motor Activity; Periaqueductal Gray; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT1A; Receptor, Serotonin, 5-HT2A; Serotonin Receptor Agonists | 2005 |
Effects of fluoxetine and buspirone on the panicolytic-like response induced by the activation of 5-HT1A and 5-HT2A receptors in the rat dorsal periaqueductal gray.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Anti-Anxiety Agents; Buspirone; Fluoxetine; Male; Microinjections; Periaqueductal Gray; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT1A; Receptor, Serotonin, 5-HT2A; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Receptor Agonists | 2006 |
Vagal pulmonary afferents and central respiratory effects of 5-HT in newborn rats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Age Factors; Amphetamines; Animals; Animals, Newborn; Decerebrate State; Diaphragm; Electric Stimulation; Hypoglossal Nerve; Injections, Intraventricular; Rats; Respiration; Serotonin; Serotonin Receptor Agonists; Vagotomy; Vagus Nerve | 2005 |
Stimulation of 5-HT 1A receptors increases the seizure threshold for picrotoxin in mice.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Drug Administration Schedule; Drug Therapy, Combination; Ketanserin; Male; Mice; Mice, Inbred CBA; Picrotoxin; Piperazines; Pyridines; Receptor, Serotonin, 5-HT1A; Seizures; Serotonin 5-HT1 Receptor Agonists; Serotonin 5-HT1 Receptor Antagonists; Serotonin 5-HT2 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists; Serotonin Antagonists; Serotonin Receptor Agonists; Stress, Physiological; Swimming | 2005 |
Factors producing a menopausal depressive-like state in mice following ovariectomy.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Affect; Amphetamines; Animals; Depression; Disease Models, Animal; Dose-Response Relationship, Drug; Fear; Female; Fertility; Maze Learning; Mice; Mice, Inbred Strains; Motivation; Motor Activity; Ovariectomy; Species Specificity | 2006 |
Imipramine and citalopram reverse corticosterone-induced alterations in the effects of the activation of 5-HT(1A) and 5-HT(2) receptors in rat frontal cortex.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Benzamides; Bridged Bicyclo Compounds, Heterocyclic; Citalopram; Corticosterone; Depression; Frontal Lobe; Imipramine; Male; Models, Animal; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT1A; Receptors, Serotonin, 5-HT2; Receptors, Serotonin, 5-HT4; Serotonin Antagonists; Serotonin Receptor Agonists; Stress, Psychological | 2006 |
The 5-HT1A receptor full agonist, 8-OH-DPAT inhibits ACTH-induced 5-HT2A receptor hyperfunction in rats: involvement of 5-HT1A receptors in the DOI-induced wet-dog shakes in ACTH-treated rats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenocorticotropic Hormone; Amphetamines; Animals; Body Temperature; Brain; Dose-Response Relationship, Drug; Hypothermia; Ketanserin; Male; Posture; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT1A; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Time Factors; Tremor | 2007 |
The PKC inhibitor, bisindolymaleimide, blocks DOI's attenuation of the effects of 8-OH-DPAT on female rat lordosis behavior.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Analysis of Variance; Animals; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Female; Indoles; Maleimides; Microinjections; Posture; Protein Kinase C; Rats; Rats, Inbred F344; Receptors, Serotonin; Serotonin Receptor Agonists; Sex Factors; Sexual Behavior, Animal; Signal Transduction; Time Factors; Ventromedial Hypothalamic Nucleus | 2007 |
Repeated co-treatment with imipramine and amantadine induces hippocampal brain-derived neurotrophic factor gene expression in rats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amantadine; Amphetamines; Animals; Antidepressive Agents; Behavior, Animal; Brain-Derived Neurotrophic Factor; Cyclic AMP Response Element-Binding Protein; Drug Therapy, Combination; Gene Expression Regulation; Hippocampus; Imipramine; Male; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Serotonin | 2007 |
Differential effects of spinal 5-HT1A receptor activation and 5-HT2A/2C receptor desensitization by chronic haloperidol.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Antipsychotic Agents; Dyskinesia, Drug-Induced; Electrophysiology; Haloperidol; Male; Rats; Rats, Wistar; Receptors, Dopamine D2; Reflex, Monosynaptic; Serotonin 5-HT1 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists; Serotonin Receptor Agonists; Spinal Cord | 2007 |
CB1 knockout mice display impaired functionality of 5-HT1A and 5-HT2A/C receptors.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Autoradiography; Behavior, Animal; Body Temperature; Female; Gene Expression Regulation; Guanosine 5'-O-(3-Thiotriphosphate); Mice; Mice, Knockout; Protein Binding; Receptor, Cannabinoid, CB1; Receptor, Serotonin, 5-HT1A; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2C; Serotonin Receptor Agonists | 2007 |
Role of serotonergic input to the ventrolateral medulla in expression of the 10-Hz sympathetic nerve rhythm.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Axons; Cats; Denervation; Ergolines; Excitatory Amino Acid Agonists; Medulla Oblongata; Microinjections; N-Methylaspartate; Piperazines; Pressoreceptors; Pyridines; Raphe Nuclei; Receptor, Serotonin, 5-HT1A; Serotonin; Serotonin 5-HT1 Receptor Agonists; Serotonin 5-HT1 Receptor Antagonists; Serotonin 5-HT2 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists; Serotonin Receptor Agonists; Sympathetic Nervous System | 2008 |
In vivo evidence for serotonin 5-HT2C receptor-mediated long-lasting excitability of lumbar spinal reflex and its functional interaction with 5-HT1A receptor in the mammalian spinal cord.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aminopyridines; Amphetamines; Animals; Drug Interactions; Electric Stimulation; Indoles; Lumbosacral Region; Male; Membrane Potentials; Motor Neurons; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT1A; Receptor, Serotonin, 5-HT2C; Reflex, Monosynaptic; Serotonin Antagonists; Serotonin Receptor Agonists; Spinal Cord | 2008 |
Alprazolam potentiates the antiaversive effect induced by the activation of 5-HT(1A) and 5-HT (2A) receptors in the rat dorsal periaqueductal gray.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Alprazolam; Amphetamines; Animals; Anti-Anxiety Agents; Dose-Response Relationship, Drug; Electric Stimulation; Male; Microinjections; Periaqueductal Gray; Rats; Rats, Wistar; Serotonin 5-HT1 Receptor Agonists; Serotonin 5-HT2 Receptor Agonists; Serotonin Receptor Agonists; Synaptic Transmission | 2008 |
Regulation of pseudosexual behavior in the parthenogenetic whiptail lizard, Cnemidophorus uniparens.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Cloning, Molecular; Female; Injections, Intraventricular; Lizards; Male; Ovariectomy; Parthenogenesis; Preoptic Area; Receptor, Serotonin, 5-HT1A; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2C; Serotonin; Serotonin 5-HT1 Receptor Agonists; Serotonin 5-HT2 Receptor Agonists; Serotonin Receptor Agonists; Sexual Behavior, Animal; Ventromedial Hypothalamic Nucleus | 2008 |
Serotonin modulates vocalizations and territorial behavior in an amphibian.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aggression; Amphetamines; Animals; Anura; Behavior, Animal; Injections, Intraperitoneal; Male; Motor Activity; Receptor, Serotonin, 5-HT1A; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; Serotonin; Serotonin Receptor Agonists; Social Behavior; Territoriality; Vocalization, Animal | 2008 |
Food restriction and streptozotocin treatment decrease 5-HT1A and 5-HT2A receptor-mediated behavioral effects in rats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Behavior, Animal; Diabetes Mellitus, Experimental; Food Deprivation; Hypoglycemic Agents; Insulin; Male; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1A; Receptor, Serotonin, 5-HT2A; Serotonin 5-HT1 Receptor Agonists; Serotonin 5-HT2 Receptor Agonists; Streptozocin | 2008 |
Serotonin 5-HT(2) and 5-HT(1A)-like receptors differentially modulate aggressive behaviors in Drosophila melanogaster.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aggression; Amphetamines; Analysis of Variance; Animals; Drosophila melanogaster; Drosophila Proteins; Drug Interactions; Female; Gene Expression; Ketanserin; Male; Membrane Glycoproteins; Motor Activity; Piperazines; Pyridines; Receptor, Serotonin, 5-HT1A; Receptors, Serotonin; Receptors, Serotonin, 5-HT2; Serotonin 5-HT1 Receptor Agonists; Serotonin 5-HT1 Receptor Antagonists; Serotonin 5-HT2 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists; Serotonin Antagonists; Serotonin Receptor Agonists; Social Behavior | 2009 |
Electrophysiological characterization of the effects of asenapine at 5-HT(1A), 5-HT(2A), alpha(2)-adrenergic and D(2) receptors in the rat brain.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Action Potentials; Adrenergic alpha-2 Receptor Agonists; Amphetamines; Animals; Apomorphine; Brain; Clonidine; Dibenzocycloheptenes; Dose-Response Relationship, Drug; Heterocyclic Compounds, 4 or More Rings; Male; Neurons; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1A; Receptor, Serotonin, 5-HT2A; Receptors, Adrenergic, alpha-2; Receptors, Dopamine D2; Serotonin 5-HT1 Receptor Agonists; Serotonin 5-HT2 Receptor Agonists | 2009 |
Individual differences in the sensitivity to serotonergic drugs: a pharmacobehavioural approach using rats selected on the basis of their response to novelty.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Avoidance Learning; Dose-Response Relationship, Drug; Exploratory Behavior; Fenfluramine; Individuality; Male; Maze Learning; Piperazines; Piperidines; Pyridines; Rats; Selective Serotonin Reuptake Inhibitors; Serotonin Antagonists; Serotonin Receptor Agonists | 2009 |
Serotonin receptor subtypes influence prolactin secretion in the turkey.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Benzazepines; Female; Pituitary Gland; Prolactin; Receptor, Serotonin, 5-HT1A; Receptor, Serotonin, 5-HT2A; Receptors, Dopamine D1; Serotonin 5-HT1 Receptor Agonists; Serotonin 5-HT2 Receptor Agonists; Serotonin Receptor Agonists; Turkeys | 2010 |
Implication of the 5-HT2A and 5-HT2C (but not 5HT1A) receptors located within the periaqueductal gray in the elevated plus-maze test-retest paradigm in mice.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Analysis of Variance; Animals; Anxiety; Behavior, Animal; Disease Models, Animal; Dose-Response Relationship, Drug; Male; Maze Learning; Mice; Microinjections; Motor Activity; Periaqueductal Gray; Pyrazines; Receptor, Serotonin, 5-HT1A; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2C; Reproducibility of Results; Serotonin 5-HT1 Receptor Agonists; Serotonin 5-HT2 Receptor Agonists; Serotonin Agents | 2009 |
Serotonergic mechanisms on breathing modulation in the rat locus coeruleus.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic alpha-Antagonists; Amphetamines; Animals; Hydroxyindoleacetic Acid; Hypercapnia; Idazoxan; Ketanserin; Locus Coeruleus; Male; Microinjections; Piperazines; Pulmonary Ventilation; Pyridines; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT1A; Receptor, Serotonin, 5-HT2A; Respiration; Serotonin; Serotonin 5-HT1 Receptor Agonists; Serotonin 5-HT1 Receptor Antagonists; Serotonin 5-HT2 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists; Serotonin Antagonists; Serotonin Receptor Agonists | 2010 |
Chronic treatment with fluoxetine decreases cerebral metabolic responses to the 5-HT1A agonist 8-hydroxy-2(di-N-propylamino)tetralin and increases those to the 5-HT2A/2C agonist 1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane and to the dopaminergic agonist
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Apomorphine; Brain; Dopamine Agonists; Down-Regulation; Drug Administration Schedule; Fluoxetine; Male; Rats; Rats, Inbred F344; Receptor, Serotonin, 5-HT1A; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Selective Serotonin Reuptake Inhibitors; Serotonin Receptor Agonists; Up-Regulation | 2010 |
HPC-1/syntaxin 1A gene knockout mice show abnormal behavior possibly related to a disruption in 5-HTergic systems.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic Uptake Inhibitors; Amphetamines; Animals; Behavior, Animal; Desipramine; Dopamine Agonists; Dopamine Antagonists; Fluoxetine; Haloperidol; Hippocampus; Humans; Hypothalamus; Inhibition, Psychological; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Phenotype; Piperazines; Quinpirole; Receptor, Serotonin, 5-HT2A; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Plasma Membrane Transport Proteins; Serotonin Receptor Agonists; Social Behavior; Syntaxin 1 | 2010 |
Inhibition by 5-HT of the synaptic responses evoked by callosal fibers on cortical neurons in the mouse.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Cerebral Cortex; Corpus Callosum; Electric Stimulation; Excitatory Postsynaptic Potentials; Mice; Mice, Inbred ICR; Neurons; Receptor, Serotonin, 5-HT1A; Receptor, Serotonin, 5-HT2A; Serotonin; Synaptic Transmission | 2010 |
A modified adjusting delay task to assess impulsive choice between isocaloric reinforcers in non-deprived male rats: effects of 5-HT₂A/C and 5-HT₁A receptor agonists.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Choice Behavior; Conditioning, Operant; Glucose; Impulsive Behavior; Male; Rats; Rats, Wistar; Reward; Saccharin; Serotonin 5-HT1 Receptor Agonists; Serotonin 5-HT2 Receptor Agonists; Time Factors | 2012 |
Electrophysiological and pharmacological properties of GABAergic cells in the dorsal raphe nucleus.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; GABAergic Neurons; Glutamate Decarboxylase; Green Fluorescent Proteins; Immunohistochemistry; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Patch-Clamp Techniques; Promoter Regions, Genetic; Raphe Nuclei; Receptor, Serotonin, 5-HT1A; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; Serotonin; Serotonin 5-HT1 Receptor Agonists; Serotonin 5-HT2 Receptor Agonists; Synaptic Potentials | 2013 |
An evaluation of the serotonin system and perseverative, compulsive, stereotypical, and hyperactive behaviors in dopamine transporter (DAT) knockout mice.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Autoreceptors; Brain; Compulsive Behavior; Dopamine Plasma Membrane Transport Proteins; Hippocampus; Hyperkinesis; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Prefrontal Cortex; Receptor, Serotonin, 5-HT1A; Reflex, Startle; Serotonin; Serotonin Receptor Agonists; Stereotyped Behavior; Time Factors | 2013 |
The antipsychotic-like effects of the mGlu group III orthosteric agonist, LSP1-2111, involves 5-HT₁A signalling.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aminobutyrates; Amphetamines; Animals; Antipsychotic Agents; Cyclohexanes; Dextroamphetamine; Disease Models, Animal; Dizocilpine Maleate; Dose-Response Relationship, Drug; Male; Mice; Phosphinic Acids; Piperazines; Psychotic Disorders; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT1A; Receptors, Metabotropic Glutamate; Signal Transduction | 2013 |
Schizophrenia-like disruptions of sensory gating by serotonin receptor stimulation in rats: effect of MDMA, DOI and 8-OH-DPAT.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Evoked Potentials; Male; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Schizophrenia; Sensory Gating | 2013 |
Activation of 5-HT receptors inhibits GABAergic transmission by pre-and post-synaptic mechanisms in layer II/III of the juvenile rat auditory cortex.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Auditory Cortex; GABA Agonists; GABAergic Neurons; Inhibitory Postsynaptic Potentials; Miniature Postsynaptic Potentials; Muscimol; Piperazines; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Ritanserin; Serotonin Receptor Agonists; Synapses | 2015 |
Directly Observable Behavioral Effects of Lorcaserin in Rats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Anti-Obesity Agents; Behavior, Animal; Benzazepines; DOM 2,5-Dimethoxy-4-Methylamphetamine; Dose-Response Relationship, Drug; Head Movements; Male; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1A; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2C; Serotonin 5-HT2 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists; Serotonin Antagonists; Serotonin Receptor Agonists; Yawning | 2015 |
Intra- and Interhemispheric Propagation of Electrophysiological Synchronous Activity and Its Modulation by Serotonin in the Cingulate Cortex of Juvenile Mice.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Bicuculline; Electric Stimulation; Electrophysiological Phenomena; GABA-A Receptor Antagonists; Gyrus Cinguli; Male; Mice, Inbred C57BL; Receptor, Serotonin, 5-HT1B; Receptor, Serotonin, 5-HT2A; Serotonin; Serotonin Receptor Agonists; Time Factors | 2016 |
Neurotoxic Effects of 5-MeO-DIPT: A Psychoactive Tryptamine Derivative in Rats.
Topics: 5-Methoxytryptamine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Analysis of Variance; Animals; Corpus Striatum; DNA Damage; Dopamine; Frontal Lobe; Glutamic Acid; Hallucinogens; Illicit Drugs; Male; Microdialysis; Motor Activity; N-Methyl-3,4-methylenedioxyamphetamine; Nucleus Accumbens; Oxidative Stress; Rats, Wistar; Serotonin | 2016 |
Effects of 5-HT
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aminopyridines; Amphetamines; Animals; Conditioning, Operant; Fluorobenzenes; Indoles; Male; Methylphenidate; Piperazines; Piperidines; Pyridines; Rats; Receptor, Serotonin, 5-HT1A; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2C; Reinforcement, Psychology; Serotonin 5-HT1 Receptor Agonists; Serotonin 5-HT1 Receptor Antagonists; Serotonin 5-HT2 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists; Serotonin Antagonists; Serotonin Receptor Agonists | 2017 |
Serotonergic modulation of nicotine-induced kinetic tremor in mice.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Fenclonine; Humans; Male; Mice; Nicotine; Ondansetron; Piperazines; Receptor, Serotonin, 5-HT1A; Receptors, Serotonin; Ritanserin; Serotonin Antagonists; Serotonin Receptor Agonists; Tremor | 2017 |
Positive regulation of raphe serotonin neurons by serotonin 2B receptors.
Topics: 3,4-Methylenedioxyamphetamine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Action Potentials; Amphetamines; Animals; Body Temperature; Central Nervous System Sensitization; Female; Fluoxetine; Indoles; Male; Mice; Mice, Knockout; Mice, Transgenic; Neurogenesis; Prepulse Inhibition; Raphe Nuclei; Receptor, Serotonin, 5-HT2B; Serotonergic Neurons; Serotonin 5-HT2 Receptor Agonists; Thiophenes; Transcription Factors | 2018 |
CB1 receptors in the paraventricular nucleus of the hypothalamus modulate the release of 5-HT and GABA to stimulate food intake in rats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Arachidonic Acids; Cyproheptadine; Drug Interactions; Eating; gamma-Aminobutyric Acid; Male; Microinjections; Paraventricular Hypothalamic Nucleus; Piperazines; Piperidines; Piperidones; Pyrazoles; Pyridines; Pyrroles; Rats; Receptor, Cannabinoid, CB1; Receptors, Serotonin, 5-HT1; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Spiro Compounds; Tritium | 2018 |
Serotonin 5-HT
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Antipsychotic Agents; Brain Waves; Cortical Synchronization; Dopamine Agonists; Dopamine Antagonists; Electroencephalography; Fluorobenzenes; Gamma Rhythm; Haloperidol; Hippocampus; Locomotion; Mice; Neural Pathways; Piperazines; Piperidines; Prefrontal Cortex; Pyridines; Quinpirole; Receptor, Serotonin, 5-HT1A; Receptor, Serotonin, 5-HT2A; Receptors, Dopamine D2; Risperidone; Serotonin Antagonists; Serotonin Receptor Agonists | 2019 |