8-hydroxy-2-(di-n-propylamino)tetralin and 4-(benzodioxan-5-yl)-1-(indan-2-yl)piperazine

8-hydroxy-2-(di-n-propylamino)tetralin has been researched along with 4-(benzodioxan-5-yl)-1-(indan-2-yl)piperazine in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's5 (41.67)18.2507
2000's6 (50.00)29.6817
2010's1 (8.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chaput, C; Millan, MJ; Newman-Tancredi, A; Verrièle, L2
Audinot, V; Bervoets, K; Brocco, M; Canton, H; Gobert, A; Lejeune, F; Mennini, T; Millan, MJ; Rivet, JM; Widdowson, P1
Herremans, AH; Mos, J; Olivier, B; Van Drimmelen, M; Van Hest, A1
Chaput, C; Millan, MJ; Newman-Tancredi, A; Rivet, J; Touzard, M; Verrièle, L1
Bertaglia, A; Cervo, L; Mocaër, E; Samanin, R1
Adhumeau, A; Brocco, M; Dekeyne, A; Gobert, A; Millan, MJ1
Millan, MJ; Newman-Tancredi, A; Verrièle, L1
Gannon, RL1
Carli, M; Dekeyne, A; Di Cara, B; Gobert, A; Jaffard, R; Lestage, P; Meneses, A; Millan, MJ; Mocaer, E; Peglion, JL; Porsolt, R; Rivet, JM; Roux, S1
Cremers, TI; de Boer, SF; Jongsma, ME; Koolhaas, JM; Steenbergen, PJ; Veenema, AH1
Belluzzi, JD; Dao, JM; Leslie, FM; Loughlin, SE; McQuown, SC1

Other Studies

12 other study(ies) available for 8-hydroxy-2-(di-n-propylamino)tetralin and 4-(benzodioxan-5-yl)-1-(indan-2-yl)piperazine

ArticleYear
Labelling of recombinant human and native rat serotonin 5-HT1A receptors by a novel, selective radioligand, [3H]-S 15535: definition of its binding profile using agonists, antagonists and inverse agonists.
    Naunyn-Schmiedeberg's archives of pharmacology, 1998, Volume: 357, Issue:3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Affinity Labels; Animals; Binding, Competitive; CHO Cells; Cricetinae; Guanine Nucleotides; Hippocampus; Humans; Male; Membranes; Piperazines; Radiopharmaceuticals; Rats; Rats, Wistar; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Receptor Agonists

1998
Novel benzodioxopiperazines acting as antagonists at postsynaptic 5-HT1A receptors and as agonists at 5-HT1A autoreceptors: a comparative pharmacological characterization with proposed 5-HT1A antagonists.
    The Journal of pharmacology and experimental therapeutics, 1994, Volume: 268, Issue:1

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Administration, Oral; Animals; Corpus Striatum; Cross-Linking Reagents; Dioxanes; Guinea Pigs; In Vitro Techniques; Male; Neurons; Piperazines; Rats; Rats, Wistar; Receptors, Adrenergic; Receptors, Dopamine; Receptors, Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Synapses

1994
S 15535 and WAY 100,635 antagonise 5-HT-stimulated [35S]GTP gamma S binding at cloned human 5-HT1A receptors.
    European journal of pharmacology, 1996, Jun-20, Volume: 307, Issue:1

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Binding, Competitive; CHO Cells; Cloning, Molecular; Cricetinae; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Piperazines; Pyridines; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Stimulation, Chemical; Tritium

1996
The putative 5-HT1A receptor antagonist DU125530 blocks the discriminative stimulus of the 5-HT1A receptor agonist flesinoxan in pigeons.
    European journal of pharmacology, 1997, May-01, Volume: 325, Issue:2-3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Buspirone; Columbidae; Discrimination Learning; Fluvoxamine; Indoles; Pindolol; Piperazines; Pyridines; Pyrimidines; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Antagonists; Serotonin Receptor Agonists; Thiazoles

1997
The 5HT(1A) receptor ligand, S15535, antagonises G-protein activation: a [35S]GTPgammaS and [3H]S15535 autoradiography study.
    European journal of pharmacology, 1999, Nov-19, Volume: 384, Issue:2-3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Autoradiography; Binding, Competitive; Brain; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); In Vitro Techniques; Ligands; Male; Piperazines; Rats; Rats, Wistar; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin; Serotonin Receptor Agonists; Sulfur Radioisotopes; Tritium

1999
Roles of 5-HT(1A) receptors in the dorsal raphe and dorsal hippocampus in anxiety assessed by the behavioral effects of 8-OH-DPAT and S 15535 in a modified Geller-Seifter conflict model.
    Neuropharmacology, 2000, Apr-03, Volume: 39, Issue:6

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Anxiety; Conditioning, Operant; Conflict, Psychological; Hippocampus; Male; Piperazines; Punishment; Pyridines; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Antagonists; Serotonin Receptor Agonists; Stereotaxic Techniques

2000
The selective serotonin (5-HT)1A receptor ligand, S15535, displays anxiolytic-like effects in the social interaction and Vogel models and suppresses dialysate levels of 5-HT in the dorsal hippocampus of freely-moving rats. A comparison with other anxiolyt
    Psychopharmacology, 2000, Volume: 152, Issue:1

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Anti-Anxiety Agents; Ataxia; Conflict, Psychological; Dialysis; Diazepam; Dose-Response Relationship, Drug; Hippocampus; Interpersonal Relations; Male; Motor Activity; Piperazines; Rats; Rats, Wistar; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists

2000
Differential modulation by GTPgammaS of agonist and inverse agonist binding to h5-HT(1A) receptors revealed by [3H]-WAY100,635.
    British journal of pharmacology, 2001, Volume: 132, Issue:2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; CHO Cells; Cricetinae; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Kinetics; Ligands; Piperazines; Pyridines; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Antagonists; Serotonin Receptor Agonists

2001
Serotonergic serotonin (1A) mixed agonists/antagonists elicit large-magnitude phase shifts in hamster circadian wheel-running rhythms.
    Neuroscience, 2003, Volume: 119, Issue:2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic alpha-Antagonists; Animals; Behavior, Animal; Circadian Rhythm; Cricetinae; Dioxins; Dose-Response Relationship, Drug; Drug Combinations; Male; Motor Activity; Photoperiod; Piperazines; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Spiro Compounds; Suprachiasmatic Nucleus

2003
The serotonin1A receptor partial agonist S15535 [4-(benzodioxan-5-yl)1-(indan-2-yl)piperazine] enhances cholinergic transmission and cognitive function in rodents: a combined neurochemical and behavioral analysis.
    The Journal of pharmacology and experimental therapeutics, 2004, Volume: 311, Issue:1

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Acetylcholine; Aging; Amnesia; Animals; Dialysis; Discrimination Learning; Drug Interactions; Hippocampus; Male; Maze Learning; Memory; Mice; Mice, Inbred C57BL; Piperazines; Prefrontal Cortex; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT1A; Recognition, Psychology; Scopolamine; Serotonin Receptor Agonists; Spatial Behavior

2004
Differences in the effects of 5-HT(1A) receptor agonists on forced swimming behavior and brain 5-HT metabolism between low and high aggressive mice.
    Psychopharmacology, 2005, Volume: 178, Issue:2-3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adaptation, Psychological; Aggression; Agonistic Behavior; Animals; Arousal; Brain; Escape Reaction; Fear; Helplessness, Learned; Injections, Intraperitoneal; Male; Mice; Mice, Inbred Strains; Motor Activity; Piperazines; Reaction Time; Selection, Genetic; Serotonin; Serotonin 5-HT1 Receptor Agonists; Serotonin Receptor Agonists; Swimming

2005
Nicotine alters limbic function in adolescent rat by a 5-HT1A receptor mechanism.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2011, Volume: 36, Issue:7

    Topics: 3,4-Dihydroxyphenylacetic Acid; 8-Hydroxy-2-(di-n-propylamino)tetralin; Age Factors; Analysis of Variance; Animals; Animals, Newborn; Autoradiography; Catecholamines; Dopamine Agonists; Drug Administration Schedule; Drug Interactions; Gene Expression Regulation; Limbic System; Locomotion; Male; Nicotine; Nicotinic Agonists; Piperazines; Protein Binding; Quinpirole; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1A; Reward; RNA, Messenger; Self Administration; Serotonin Plasma Membrane Transport Proteins; Serotonin Receptor Agonists; Time Factors

2011