8-hydroxy-2-(di-n-propylamino)tetralin has been researched along with 4-(2'-methoxyphenyl)-1-(2'-(n-(2''-pyridinyl)-4-iodobenzamido)ethyl)piperazine in 26 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 13 (50.00) | 18.2507 |
| 2000's | 10 (38.46) | 29.6817 |
| 2010's | 3 (11.54) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chattopadhyay, A; Harikumar, KG; Kalipatnapu, S; Pucadyil, TJ | 1 |
| Burris, KD; Butkerait, P; Graham, TE; Hallak, H; Manning, DR; Miller, HA; Molinoff, PB; Zheng, Y | 1 |
| Frazer, A; Thielen, RJ | 1 |
| Frederick, D; Kung, HF; Kung, MP; Zhuang, ZP | 1 |
| Fangon, NB; Frazer, A; Thielen, RJ | 1 |
| De Lanerolle, NC; Shaikh, MB; Siegel, A | 1 |
| Leander, JD; Wolff, MC | 1 |
| Ahlemeyer, B; Krieglstein, J | 1 |
| Hull, EM; Lorrain, DS; Matuszewich, L | 1 |
| Cook, DF; Wirtshafter, D | 1 |
| Bjorvatn, B; Fornal, CA; Jacobs, BL; Martín, FJ; Metzler, CW | 1 |
| Koob, GF; Parsons, LH; Weiss, F | 1 |
| Dominguez, J; Hull, EM; Lorrain, DS; Matuszewich, L; Putnam, SK; Trujillo, R | 1 |
| Heils, A; Lesch, KP; Li, Q; Murphy, DL; Van De Kar, LD; Wichems, C | 1 |
| Ferreira, M; Gillis, RA; Sahibzada, N; Taveira-DaSilva, AM; Wasserman, AM | 1 |
| Chen, CA; Manning, DR | 1 |
| Moerschbaecher, JM; Winsauer, PJ | 1 |
| Harrison, AA; Markou, A | 1 |
| Bjorvatn, B; Grønli, J; Sørensen, E; Ursin, R | 1 |
| Amstislavskaya, TG; Popova, NK | 1 |
| Bingaman, M; Gillis, RA; Pace, PP; Taveira-DaSilva, AM; Teng, YD; Wrathall, JR | 1 |
| Bhatt, S; Hassanain, M; Siegel, A | 1 |
| Kondaurova, EM; Naumenko, VS; Popova, NK | 1 |
| Bai, YJ; Cao, JX; Cui, SY; Cui, XY; Wang, LE; Zhang, J; Zhang, QY; Zhang, YH; Zhao, YY | 1 |
| Che, CT; Huang, Z; Ip, SP; Mao, QQ; Xian, YF | 1 |
| Wang, LE; Yin, YQ; Zhang, XQ; Zhang, YH | 1 |
26 other study(ies) available for 8-hydroxy-2-(di-n-propylamino)tetralin and 4-(2'-methoxyphenyl)-1-(2'-(n-(2''-pyridinyl)-4-iodobenzamido)ethyl)piperazine
| Article | Year |
|---|---|
Ligand binding characteristics of the human serotonin1A receptor heterologously expressed in CHO cells.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aminopyridines; Animals; Binding Sites; Binding, Competitive; Cell Membrane; CHO Cells; Clone Cells; Cricetinae; Cricetulus; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Kinetics; Ligands; Piperazines; Radioligand Assay; Receptor, Serotonin, 5-HT1A; Sensitivity and Specificity; Serotonin Antagonists; Serotonin Receptor Agonists; Transfection; Tritium | 2004 |
Expression of the human 5-hydroxytryptamine1A receptor in Sf9 cells. Reconstitution of a coupled phenotype by co-expression of mammalian G protein subunits.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amino Acid Sequence; Aminopyridines; Animals; Baculoviridae; Base Sequence; Cell Line; GTP-Binding Proteins; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Humans; Molecular Sequence Data; Peptide Fragments; Piperazines; Protein Processing, Post-Translational; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Recombinant Proteins; Signal Transduction; Spodoptera | 1995 |
Effects of novel 5-HT1A receptor antagonists on measures of post-synaptic 5-HT1A receptor activation in vivo.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aminopyridines; Animals; Body Temperature; Male; Piperazines; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Serotonin Antagonists | 1995 |
In vivo binding of [123I]4-(2'-methoxyphenyl)-1-[2'-(N-2"-pyridinyl)- p-iodobenzamido-]ethyl-piperazine, p-MPPI, to 5-HT1A receptors in rat brain.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aminopyridines; Animals; Autoradiography; Brain; Iodine Radioisotopes; Isotope Labeling; Ligands; Male; Piperazines; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Serotonin Antagonists; Tissue Distribution | 1994 |
4-(2'-Methoxyphenyl)-1-[2'-[N-(2"-pyridinyl)-p-iodobenzamido]ethyl] piperazine and 4-(2'-methoxyphenyl)-1-[2'-[N-(2"-pyridinyl)-p- fluorobenzamido]ethyl]piperazine, two new antagonists at pre- and postsynaptic serotonin-1A receptors.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aminopyridines; Animals; Autoreceptors; Body Temperature; Brain Chemistry; Dose-Response Relationship, Drug; Guanylyl Imidodiphosphate; Hydroxyindoleacetic Acid; Male; Piperazines; Posture; Rats; Rats, Sprague-Dawley; Serotonin; Serotonin Antagonists | 1996 |
Serotonin 5-HT1A and 5-HT2/1C receptors in the midbrain periaqueductal gray differentially modulate defensive rage behavior elicited from the medial hypothalamus of the cat.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aminopyridines; Animals; Behavior, Animal; Cats; Female; Hypothalamus; Immunohistochemistry; Male; Mesencephalon; Periaqueductal Gray; Piperazines; Receptors, Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists | 1997 |
Differentiation of 5-HT1A receptor ligands by drug discrimination.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Aminopyridines; Animals; Behavior, Animal; Buspirone; Columbidae; Cyclohexylamines; Discrimination Learning; Dose-Response Relationship, Drug; Idazoxan; Ligands; Male; Pindolol; Piperazines; Pyridines; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Antagonists; Serotonin Receptor Agonists | 1997 |
Stimulation of 5-HT1A receptor inhibits apoptosis induced by serum deprivation in cultured neurons from chick embryo.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic beta-Antagonists; Aminopyridines; Animals; Apoptosis; Cells, Cultured; Chick Embryo; Chlorpromazine; Culture Media, Serum-Free; Dopamine Antagonists; Nerve Growth Factors; Neurons; Neuroprotective Agents; Piperazines; Propranolol; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Antagonists; Serotonin Receptor Agonists; Telencephalon | 1997 |
8-OH-DPAT influences extracellular levels of serotonin and dopamine in the medial preoptic area of male rats.
Topics: 5,7-Dihydroxytryptamine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Aminopyridines; Animals; Carrier Proteins; Dopamine; Extracellular Space; Male; Membrane Glycoproteins; Membrane Transport Proteins; Microdialysis; Microinjections; Nerve Tissue Proteins; Piperazines; Preoptic Area; Rats; Rats, Inbred Strains; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin; Serotonin Agents; Serotonin Antagonists; Serotonin Plasma Membrane Transport Proteins; Serotonin Receptor Agonists; Sexual Behavior, Animal | 1998 |
Serotonin-1B agonists induce compartmentally organized striatal Fos expression in rats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aminopyridines; Animals; Corpus Striatum; Immunohistochemistry; Indoles; Male; Nerve Tissue Proteins; Piperazines; Piperidines; Proto-Oncogene Proteins c-fos; Pyridines; Rats; Rats, Sprague-Dawley; Serotonin Antagonists; Serotonin Receptor Agonists | 1998 |
The 5-HT1A receptor antagonist p-MPPI blocks 5-HT1A autoreceptors and increases dorsal raphe unit activity in awake cats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Action Potentials; Aminopyridines; Animals; Autoreceptors; Cats; Drug Interactions; Electroencephalography; Electrophysiology; Male; Motor Activity; Piperazines; Raphe Nuclei; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Antagonists; Serotonin Receptor Agonists; Wakefulness | 1998 |
Serotonin1B receptor stimulation enhances cocaine reinforcement.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aminopyridines; Animals; Cocaine; Cocaine-Related Disorders; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Indoles; Injections, Intraventricular; Male; Oxadiazoles; Piperazines; Pyridines; Pyrroles; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT1B; Receptors, Serotonin; Self Administration; Serotonin Antagonists; Serotonin Receptor Agonists | 1998 |
Partial antagonism of 8-OH-DPAT'S effects on male rat sexual behavior with a D2, but not a 5-HT1A, antagonist.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aminopyridines; Animals; Copulation; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Ejaculation; Male; Piperazines; Preoptic Area; Raclopride; Rats; Rats, Long-Evans; Reaction Time; Salicylamides; Serotonin Antagonists; Sexual Behavior, Animal | 1999 |
Reduction of 5-hydroxytryptamine (5-HT)(1A)-mediated temperature and neuroendocrine responses and 5-HT(1A) binding sites in 5-HT transporter knockout mice.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenocorticotropic Hormone; Aminopyridines; Animals; Autoradiography; Body Temperature; Carrier Proteins; Corticosterone; Dose-Response Relationship, Drug; Hypothalamus; Membrane Glycoproteins; Membrane Transport Proteins; Mice; Mice, Knockout; Nerve Tissue Proteins; Neurosecretory Systems; Oxytocin; Piperazines; Pyridines; Raphe Nuclei; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin; Serotonin Antagonists; Serotonin Plasma Membrane Transport Proteins; Serotonin Receptor Agonists; Time Factors | 1999 |
Reversal of morphine-induced apnea in the anesthetized rat by drugs that activate 5-hydroxytryptamine(1A) receptors.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aminopyridines; Animals; Apnea; Buspirone; Diaphragm; Drug Interactions; Electromyography; Male; Morphine; Muscle Contraction; Piperazines; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists | 2000 |
Regulation of galpha i palmitoylation by activation of the 5-hydroxytryptamine-1A receptor.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aminopyridines; Animals; CHO Cells; Cricetinae; GTP-Binding Protein alpha Subunits, Gi-Go; GTP-Binding Protein alpha Subunits, Gs; Humans; Palmitic Acid; Piperazines; Protein Processing, Post-Translational; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Signal Transduction; Virulence Factors, Bordetella | 2000 |
Differential effects of 5-HT agonists and antagonists on the repeated acquisition and performance of response sequences in monkeys.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aminopyridines; Amphetamines; Animals; Behavior, Animal; Dose-Response Relationship, Drug; Ergolines; Learning; Macaca fascicularis; Macaca mulatta; Piperazines; Pyridines; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Ritanserin; Serotonin Antagonists; Serotonin Receptor Agonists | 2000 |
Serotonergic manipulations both potentiate and reduce brain stimulation reward in rats: involvement of serotonin-1A receptors.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aminopyridines; Animals; Brain; Dose-Response Relationship, Drug; Fluoxetine; Male; Piperazines; Raphe Nuclei; Rats; Rats, Wistar; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Reward; Serotonin Antagonists; Serotonin Receptor Agonists | 2001 |
The selective 5-HT(1A) receptor antagonist p-MPPI antagonizes sleep--waking and behavioural effects of 8-OH-DPAT in rats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aminopyridines; Animals; Arousal; Dose-Response Relationship, Drug; Injections, Intraperitoneal; Injections, Subcutaneous; Male; Piperazines; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Antagonists; Sleep Stages; Wakefulness | 2001 |
Involvement of the 5-HT(1A) and 5-HT(1B) serotonergic receptor subtypes in sexual arousal in male mice.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aminopyridines; Animals; Female; Male; Mice; Mice, Inbred BALB C; Mice, Inbred CBA; Motivation; Piperazines; Quinoxalines; Receptor, Serotonin, 5-HT1B; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Antagonists; Serotonin Receptor Agonists; Sexual Behavior, Animal | 2002 |
Serotonin 1A receptor agonists reverse respiratory abnormalities in spinal cord-injured rats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aminopyridines; Animals; Buspirone; Female; Piperazines; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Respiration; Respiratory Function Tests; Respiratory System Abnormalities; Serotonin Antagonists; Serotonin Receptor Agonists; Spinal Cord Injuries; Wounds, Nonpenetrating | 2003 |
Differential modulation of feline defensive rage behavior in the medial hypothalamus by 5-HT1A and 5-HT2 receptors.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aggression; Aminopyridines; Animals; Behavior, Animal; Cats; Dose-Response Relationship, Drug; Electric Stimulation; Female; Hypothalamus, Middle; Indophenol; Periaqueductal Gray; Piperazines; Predatory Behavior; Rage; Reaction Time; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Agents; Serotonin Antagonists; Time Factors | 2003 |
Central 5-HT3 receptor-induced hypothermia in mice: interstrain differences and comparison with hypothermia mediated via 5-HT1A receptor.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aminopyridines; Animals; Biguanides; Blood-Brain Barrier; Body Temperature; Dose-Response Relationship, Drug; Hypothermia; Male; Mice; Mice, Inbred Strains; Ondansetron; Piperazines; Receptor, Serotonin, 5-HT1A; Receptors, Serotonin, 5-HT3; Serotonin 5-HT1 Receptor Antagonists; Serotonin 5-HT3 Receptor Agonists; Serotonin Antagonists; Serotonin Receptor Agonists; Species Specificity | 2009 |
Potentiating effect of spinosin, a C-glycoside flavonoid of Semen Ziziphi spinosae, on pentobarbital-induced sleep may be related to postsynaptic 5-HT(1A) receptors.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aminopyridines; Animals; Drug Synergism; Drug Therapy, Combination; Drugs, Chinese Herbal; Flavonoids; Glycosides; Male; Monosaccharides; Pentobarbital; Phytotherapy; Piperazines; Rats; Rats, Sprague-Dawley; Seeds; Serotonin; Serotonin 5-HT1 Receptor Antagonists; Sleep; Sleep Initiation and Maintenance Disorders; Sleep, REM; Time Factors; Wakefulness; Ziziphus | 2010 |
Role of 5-HT(1A) and 5-HT(1B) receptors in the antidepressant-like effect of piperine in the forced swim test.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Alkaloids; Aminopyridines; Animals; Antidepressive Agents; Benzodioxoles; Data Interpretation, Statistical; Male; Methiothepin; Mice; Mice, Inbred ICR; Motor Activity; Piperazines; Piperidines; Polyunsaturated Alkamides; Propanolamines; Pyridines; Receptor, Serotonin, 5-HT1A; Receptor, Serotonin, 5-HT1B; Serotonin 5-HT1 Receptor Agonists; Serotonin 5-HT1 Receptor Antagonists; Swimming | 2011 |
Augmentative effect of spinosin on pentobarbital-induced loss of righting reflex in mice associated with presynaptic 5-HT1A receptor.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Administration, Oral; Aminopyridines; Analysis of Variance; Animals; Drugs, Chinese Herbal; Flavonoids; Hypothermia; Male; Mice; Mice, Inbred ICR; Pentobarbital; Piperazines; Receptor, Serotonin, 5-HT1A; Receptors, Presynaptic; Reflex, Righting; Serotonin Receptor Agonists | 2012 |