Page last updated: 2024-09-05

8-gingerol and shogaol

8-gingerol has been researched along with shogaol in 13 studies

Compound Research Comparison

Studies
(8-gingerol)
Trials
(8-gingerol)
Recent Studies (post-2010)
(8-gingerol)
Studies
(shogaol)
Trials
(shogaol)
Recent Studies (post-2010) (shogaol)
220192984228

Protein Interaction Comparison

ProteinTaxonomy8-gingerol (IC50)shogaol (IC50)
Cytochrome P450 3A4Homo sapiens (human)4
Polyunsaturated fatty acid 5-lipoxygenaseHomo sapiens (human)7.4
Transient receptor potential cation channel subfamily V member 1Homo sapiens (human)0.29

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (7.69)29.6817
2010's11 (84.62)24.3611
2020's1 (7.69)2.80

Authors

AuthorsStudies
Altmann, KH; Gertsch, J; Huonker, P; Nievergelt, A; Schoop, R1
Chen, H; Chen, X; Hu, Y; Lv, L; Parks, TA; Sang, S; Soroka, D; Warin, RF; Zhu, Y1
Ha, SK; Kim, HJ; Kim, IS; Nakamura, K; Rehman, SU; Yoo, HH1
Agbedahunsi, JM; Ahmed, T; Choudhary, MI; Ghayur, MN; Gilani, AH; Houghton, PJ; Khalid, A; Nawaz, SA1
Balijepalli, MK; Dugasani, S; Korlakunta, JN; Nadarajah, VD; Pichika, MR; Tandra, S1
Elz, S; Lehmann, J; Pertz, HH; Roth-Ehrang, R1
Cai, B; Li, J; Li, W; Peng, W1
Aneja, R; Asif, G; Brahmbhatt, M; Gundala, SR; Shamsi, SA1
Emala, CW; Townsend, EA; Wakita, R; Xu, C; Zhang, Y1
Aneja, R; Cantuaria, G; Donthamsetty, S; Gundala, SR; Jadhav, GR; Mukkavilli, R; Reid, MD; Vangala, S; Yang, C1
Jung, MY; Park, SY1
Broccoli, M; Budriesi, R; Graziadio, A; Leoni, A; Lianza, M; Micucci, M; Poli, F; Venturini, A1
Cao, H; Li, J; Li, W; Liu, S; Meng, J; Sun, Y; Wang, S; Zhang, Y1

Other Studies

13 other study(ies) available for 8-gingerol and shogaol

ArticleYear
Identification of serotonin 5-HT1A receptor partial agonists in ginger.
    Bioorganic & medicinal chemistry, 2010, May-01, Volume: 18, Issue:9

    Topics: Anti-Anxiety Agents; Caco-2 Cells; Catechols; Cell Line; Fatty Alcohols; Humans; Molecular Structure; Serotonin 5-HT1 Receptor Agonists; Zingiber officinale

2010
Metabolism of [6]-shogaol in mice and in cancer cells.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:4

    Topics: Animals; Anticarcinogenic Agents; Apoptosis; Biotransformation; Catechols; Cell Line, Tumor; Cell Proliferation; Chromatography, High Pressure Liquid; Feces; Female; Humans; Magnetic Resonance Spectroscopy; Mice; Mice, Inbred C57BL; Molecular Structure; Plant Extracts; Spectrometry, Mass, Electrospray Ionization; Zingiber officinale

2012
Effects of 6-paradol, an unsaturated ketone from gingers, on cytochrome P450-mediated drug metabolism.
    Bioorganic & medicinal chemistry letters, 2017, 04-15, Volume: 27, Issue:8

    Topics: Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Guaiacol; Humans; Ketones; Microsomes, Liver; Pharmaceutical Preparations; Recombinant Proteins; Zingiber officinale

2017
Muscarinic, Ca(++) antagonist and specific butyrylcholinesterase inhibitory activity of dried ginger extract might explain its use in dementia.
    The Journal of pharmacy and pharmacology, 2008, Volume: 60, Issue:10

    Topics: Acetylcholine; Alzheimer Disease; Animals; Atropine; Butyrylcholinesterase; Calcium; Calcium Channel Blockers; Catechols; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Drug Synergism; Fatty Alcohols; Gastric Fundus; In Vitro Techniques; Molecular Structure; Muscarinic Agonists; Parasympatholytics; Physostigmine; Plant Extracts; Rats; Rats, Sprague-Dawley; Rhizome; Verapamil; Zingiber officinale

2008
Comparative antioxidant and anti-inflammatory effects of [6]-gingerol, [8]-gingerol, [10]-gingerol and [6]-shogaol.
    Journal of ethnopharmacology, 2010, Feb-03, Volume: 127, Issue:2

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Catechols; Cell Line; Fatty Alcohols; Humans; Mice; Plant Extracts; Structure-Activity Relationship; Zingiber officinale

2010
Effects of ginger constituents on the gastrointestinal tract: role of cholinergic M3 and serotonergic 5-HT3 and 5-HT4 receptors.
    Planta medica, 2011, Volume: 77, Issue:10

    Topics: Animals; Antiemetics; Catechols; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Esophagus; Fatty Alcohols; Gastrointestinal Tract; Guinea Pigs; Ileum; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Myenteric Plexus; Nausea; Phytotherapy; Plants, Medicinal; Rats; Rats, Wistar; Receptor, Muscarinic M3; Receptors, G-Protein-Coupled; Receptors, Serotonin, 5-HT3; Receptors, Serotonin, 5-HT4; Serotonin Antagonists; Vomiting; Zingiber officinale

2011
[Effect of Zingiber offiicinale and Aconitum cainichaeli before and after compatibility on contents of four gingerols].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2012, Volume: 37, Issue:14

    Topics: Aconitum; Catechols; Drug Compounding; Drug Synergism; Fatty Alcohols; Zingiber officinale

2012
Ginger phytochemicals exhibit synergy to inhibit prostate cancer cell proliferation.
    Nutrition and cancer, 2013, Volume: 65, Issue:2

    Topics: Antineoplastic Agents, Phytogenic; Catechols; Cell Line, Tumor; Cell Proliferation; Chromatography, High Pressure Liquid; Drug Synergism; Fatty Alcohols; Humans; Male; Phytochemicals; Plant Extracts; Prostatic Neoplasms; Zingiber officinale

2013
Active components of ginger potentiate β-agonist-induced relaxation of airway smooth muscle by modulating cytoskeletal regulatory proteins.
    American journal of respiratory cell and molecular biology, 2014, Volume: 50, Issue:1

    Topics: Adrenergic beta-Agonists; Asthma; Catechols; Cell Line; Cyclic Nucleotide Phosphodiesterases, Type 4; Cytoskeletal Proteins; Fatty Alcohols; HSP20 Heat-Shock Proteins; Humans; Intracellular Signaling Peptides and Proteins; Muscle Proteins; Muscle Relaxation; Muscle, Smooth; Myocytes, Smooth Muscle; Myosin Light Chains; Phosphatidylinositols; Phospholipase C beta; Phosphoprotein Phosphatases; Phosphoric Monoester Hydrolases; Phosphorylation; Plant Extracts; Potassium Channels; rhoA GTP-Binding Protein; Zingiber officinale

2014
Modulation of cytochrome P450 metabolism and transport across intestinal epithelial barrier by ginger biophenolics.
    PloS one, 2014, Volume: 9, Issue:9

    Topics: Caco-2 Cells; Catechols; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Fatty Alcohols; Gene Expression Regulation; Humans; Intestinal Mucosa; Microsomes, Liver; Plant Extracts; Zingiber officinale

2014
UHPLC-ESI-MS/MS for the Quantification of Eight Major Gingerols and Shogaols in Ginger Products: Effects of Ionization Polarity and Mobile Phase Modifier on the Sensitivity.
    Journal of food science, 2016, Volume: 81, Issue:10

    Topics: Catechols; Chromatography, High Pressure Liquid; Fatty Alcohols; Formates; Ions; Mass Spectrometry; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Zingiber officinale

2016
Ayurvedic preparation of Zingiber officinale Roscoe: effects on cardiac and on smooth muscle parameters.
    Natural product research, 2018, Volume: 32, Issue:18

    Topics: Asia; Cardiovascular System; Catechols; Chromatography, High Pressure Liquid; Fatty Alcohols; Humans; Medicine, Ayurvedic; Muscle, Smooth; Plant Extracts; Rhizome; Zingiber officinale

2018
A network pharmacology integrated pharmacokinetics strategy to investigate the pharmacological mechanism of absorbed components from crude and processed Zingiberis Rhizoma on deficiency-cold and hemorrhagic syndrome.
    Journal of ethnopharmacology, 2023, Jan-30, Volume: 301

    Topics: Animals; Diacetyl; Drugs, Chinese Herbal; Network Pharmacology; Rats

2023