Page last updated: 2024-09-05

8-gingerol and 6-paradol

8-gingerol has been researched along with 6-paradol in 5 studies

Compound Research Comparison

Studies
(8-gingerol)
Trials
(8-gingerol)
Recent Studies (post-2010)
(8-gingerol)
Studies
(6-paradol)
Trials
(6-paradol)
Recent Studies (post-2010) (6-paradol)
2201926118

Protein Interaction Comparison

ProteinTaxonomy8-gingerol (IC50)6-paradol (IC50)
Cytochrome P450 3A4Homo sapiens (human)5.8
Cytochrome P450 2C8Homo sapiens (human)4.8
Cytochrome P450 2D6Homo sapiens (human)3.8
Cytochrome P450 2B6Homo sapiens (human)6.2
Cytochrome P450 2C19Homo sapiens (human)5.8

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's4 (80.00)24.3611
2020's1 (20.00)2.80

Authors

AuthorsStudies
Chen, H; Chen, X; Hu, Y; Lv, L; Parks, TA; Sang, S; Soroka, D; Warin, RF; Zhu, Y1
Bucar, F; Gröblacher, B; Kunert, O; Maier, V1
Ha, SK; Kim, HJ; Kim, IS; Nakamura, K; Rehman, SU; Yoo, HH1
Bang, JK; Byun, Y; Cha, E; Choi, H; Ham, SY; Kim, HS; Park, HD; Shin, Y; Son, SH1
Cao, H; Li, J; Li, W; Liu, S; Meng, J; Sun, Y; Wang, S; Zhang, Y1

Other Studies

5 other study(ies) available for 8-gingerol and 6-paradol

ArticleYear
Metabolism of [6]-shogaol in mice and in cancer cells.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:4

    Topics: Animals; Anticarcinogenic Agents; Apoptosis; Biotransformation; Catechols; Cell Line, Tumor; Cell Proliferation; Chromatography, High Pressure Liquid; Feces; Female; Humans; Magnetic Resonance Spectroscopy; Mice; Mice, Inbred C57BL; Molecular Structure; Plant Extracts; Spectrometry, Mass, Electrospray Ionization; Zingiber officinale

2012
Putative mycobacterial efflux inhibitors from the seeds of Aframomum melegueta.
    Journal of natural products, 2012, Jul-27, Volume: 75, Issue:7

    Topics: Anti-Bacterial Agents; Catechols; Drug Resistance, Multiple; Ethidium; Fatty Alcohols; Guaiacol; Ketones; Microbial Sensitivity Tests; Molecular Structure; Mycobacterium smegmatis; Nuclear Magnetic Resonance, Biomolecular; Seeds; Zingiberaceae

2012
Effects of 6-paradol, an unsaturated ketone from gingers, on cytochrome P450-mediated drug metabolism.
    Bioorganic & medicinal chemistry letters, 2017, 04-15, Volume: 27, Issue:8

    Topics: Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Guaiacol; Humans; Ketones; Microsomes, Liver; Pharmaceutical Preparations; Recombinant Proteins; Zingiber officinale

2017
Structure-Activity Relationships of 6- and 8-Gingerol Analogs as Anti-Biofilm Agents.
    Journal of medicinal chemistry, 2017, 12-14, Volume: 60, Issue:23

    Topics: Anti-Bacterial Agents; Bacterial Proteins; Biofilms; Catechols; Fatty Alcohols; Humans; Molecular Docking Simulation; Pseudomonas aeruginosa; Pseudomonas Infections; Quorum Sensing; Trans-Activators

2017
A network pharmacology integrated pharmacokinetics strategy to investigate the pharmacological mechanism of absorbed components from crude and processed Zingiberis Rhizoma on deficiency-cold and hemorrhagic syndrome.
    Journal of ethnopharmacology, 2023, Jan-30, Volume: 301

    Topics: Animals; Diacetyl; Drugs, Chinese Herbal; Network Pharmacology; Rats

2023