8-cyclopentyl-1,3-dimethylxanthine has been researched along with n(6)-cyclopentyladenosine in 31 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 18 (58.06) | 18.2507 |
| 2000's | 13 (41.94) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jacobson, KA; van Galen, PJ; Williams, M | 1 |
| Bey, P; Demeter, DA; Dudley, MW; Lentz, NL; Meng, EC; Ogden, AM; Peet, NP; Weintraub, HJ | 1 |
| Beukers, MW; Dalpiaz, A; IJzerman, AP; Schofield, PR; Townsend-Nicholson, A | 1 |
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Garaschuk, O; Kovalchuk, Yu; Krishtal, O | 1 |
| Fredholm, BB; Gerwins, P | 1 |
| Huguenard, JR; Ulrich, D | 1 |
| Appel, S; Danhof, M; IJzerman, AP; Langemeijer, MW; Mathôt, RA | 1 |
| Delle Donne, KT; Sonsalla, PK | 1 |
| de Carolis, AS; Pèzzola, A; Popoli, P | 1 |
| Crosson, CE; DeBenedetto, R; Gidday, JM | 1 |
| Appel, S; Danhof, M; IJzerman, AP; Mathôt, RA; Soudijn, W; van Schaick, EA | 1 |
| Bartus, RT; Jacobson, KA; Paul, IA; Von Lubitz, DK | 1 |
| Frisella, WA; Sturm, CD; Yoon, KW | 1 |
| Broadley, KJ; Maddock, HL | 1 |
| Broadley, KJ; Ford, WR | 1 |
| Amanatullah, DF; Clair, T; Liotta, LA; Schetz, JA; Stracke, ML; Woodhouse, EC | 1 |
| Bockaert, J; Manzoni, O; Pujalte, D; Williams, J | 1 |
| Kitamura, Y; Matsuoka, Y; Ohta, S; Okazaki, M; Sekino, Y; Takata, K; Taniguchi, T | 1 |
| Lobner, D | 1 |
| Antoniou, K; Ferré, S; Fuxe, K; Goldberg, SR; Justinova, Z; Karcz-Kubicha, M; Müller, CE; Pezzola, A; Popoli, P; Quarta, D; Reggio, R; Solinas, M; Terasmaa, A | 1 |
| Kimura, M; Saitoh, N; Takahashi, T | 1 |
| Antoniou, K; Ferre, S; Goldberg, SR; Highkin, JL; Hockemeyer, J; Justinova, Z; Munzar, P; Pappas, LA; Segal, PN; Solinas, M | 1 |
| Ho, CM; Ho, ST; Peng, SC; Su, CK; Tsai, SK | 1 |
| Herrero, JF; Ramos-Zepeda, G; Rosenow, S; Schröder, W | 1 |
| Inoue, M; Kawamura, Y; Kudo, Y; Manita, S; Miyakawa, H; Sato, K | 1 |
| Ferré, S; Goldberg, SR; Karcz-Kubicha, M; Müller, CE; Schindler, CW; Tella, SR; Thorndike, EB | 1 |
| de Ligt, RA; IJzerman, AP; Leurs, R; Lorenzen, A; Rivkees, SA | 1 |
| Amini, A; Fathollahi, Y; Mirnajafi-Zadeh, J; Mohammad-Zadeh, M | 1 |
| Brown, R; Fredholm, BB; Lai, EY; Mrowka, R; Patzak, A; Persson, AE; Persson, PB; Spielmann, N; Steege, A | 1 |
| Fan, W; Kaplan, GB; Klufas, MA; Leite-Morris, KA | 1 |
1 review(s) available for 8-cyclopentyl-1,3-dimethylxanthine and n(6)-cyclopentyladenosine
| Article | Year |
|---|---|
Adenosine receptors: pharmacology, structure-activity relationships, and therapeutic potential.
Topics: Adenosine; Animals; Humans; Models, Chemical; Receptors, Purinergic; Second Messenger Systems; Structure-Activity Relationship | 1992 |
30 other study(ies) available for 8-cyclopentyl-1,3-dimethylxanthine and n(6)-cyclopentyladenosine
| Article | Year |
|---|---|
A novel synthesis of xanthines: support for a new binding mode for xanthines with respect to adenosine at adenosine receptors.
Topics: Adenosine; Animals; Dogs; Humans; Molecular Conformation; Molecular Structure; Protein Binding; Rats; Receptors, Purinergic; Structure-Activity Relationship; Theophylline; Xanthines | 1990 |
Thermodynamics of full agonist, partial agonist, and antagonist binding to wild-type and mutant adenosine A1 receptors.
Topics: Adenosine; Alanine; Amino Acid Substitution; Animals; Binding, Competitive; CHO Cells; Cricetinae; Entropy; Humans; Kinetics; Point Mutation; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Radioligand Assay; Rats; Receptors, Purinergic P1; Theophylline; Thermodynamics; Threonine; Transfection; Xanthines | 1998 |
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Adenosine-dependent enhancement by methylxanthines of excitatory synaptic transmission in hippocampus of rats.
Topics: Adenosine; Animals; Dose-Response Relationship, Drug; Drug Synergism; Evoked Potentials; Hippocampus; In Vitro Techniques; N-Methylaspartate; Pyramidal Tracts; Rats; Rats, Inbred Strains; Synapses; Synaptic Transmission; Theophylline | 1992 |
ATP and its metabolite adenosine act synergistically to mobilize intracellular calcium via the formation of inositol 1,4,5-trisphosphate in a smooth muscle cell line.
Topics: Adenosine; Adenosine Deaminase; Adenosine Triphosphate; Animals; Calcium; Cell Line; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Inositol 1,4,5-Trisphosphate; Kinetics; Leiomyosarcoma; Muscle, Smooth; Pertussis Toxin; Purinergic Antagonists; Receptors, Purinergic; Theophylline; Type C Phospholipases; Virulence Factors, Bordetella | 1992 |
Purinergic inhibition of GABA and glutamate release in the thalamus: implications for thalamic network activity.
Topics: Adenosine; Animals; Bicuculline; Electric Conductivity; Excitatory Amino Acid Antagonists; Female; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Male; Quinoxalines; Rats; Receptors, Purinergic P1; Synapses; Thalamus; Theophylline | 1995 |
Modelling of the pharmacodynamic interaction of an A1 adenosine receptor agonist and antagonist in vivo: N6-cyclopentyladenosine and 8-cyclopentyltheophylline.
Topics: Adenosine; Animals; Blood Pressure; Blood Proteins; Heart Rate; Male; Models, Chemical; Protein Binding; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptors, Purinergic P1; Theophylline | 1995 |
Protection against methamphetamine-induced neurotoxicity to neostriatal dopaminergic neurons by adenosine receptor activation.
Topics: Adenosine; Animals; Caffeine; Corpus Striatum; Dopamine; Male; Methamphetamine; Mice; MPTP Poisoning; Receptors, Purinergic P1; Theophylline; Tyrosine 3-Monooxygenase | 1994 |
Modulation of striatal adenosine A1 and A2 receptors induces rotational behaviour in response to dopaminergic stimulation in intact rats.
Topics: Adenosine; Animals; Behavior, Animal; Corpus Striatum; Dextroamphetamine; Dopamine; Injections, Intraperitoneal; Male; Phenethylamines; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptors, Purinergic P1; Synaptic Transmission; Theobromine; Theophylline | 1994 |
Functional evidence for retinal adenosine receptors.
Topics: Adenosine; Animals; Cattle; Dopamine; Dose-Response Relationship, Drug; Muscle, Smooth, Vascular; Receptors, Purinergic P1; Retina; Retinal Vessels; Swine; Theophylline; Vasodilation | 1994 |
High-performance liquid chromatography of the adenosine A1 agonist N6-cyclopentyladenosine and the A1 antagonist 8-cyclopentyltheophylline and its application in a pharmacokinetic study in rats.
Topics: Adenosine; Animals; Chromatography, High Pressure Liquid; Drug Stability; Hydrogen-Ion Concentration; Kinetics; Ligands; Male; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptors, Purinergic P1; Theophylline | 1993 |
Effects of chronic administration of adenosine A1 receptor agonist and antagonist on spatial learning and memory.
Topics: Adenosine; Animals; Dose-Response Relationship, Drug; Injections, Intraperitoneal; Learning; Male; Memory; Mice; Mice, Inbred C57BL; Motor Activity; Spatial Behavior; Theophylline | 1993 |
Attenuation of potassium cyanide-mediated neuronal cell death by adenosine.
Topics: Adenosine; Animals; Cell Death; Cells, Cultured; Dizocilpine Maleate; Hippocampus; Neurons; Osmolar Concentration; Potassium Cyanide; Purinergic Antagonists; Theobromine; Theophylline | 1993 |
P1-purinoceptor-mediated vasodilatation and vasoconstriction in hypoxia.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Guinea Pigs; Hypoxia; In Vitro Techniques; Indomethacin; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Phenethylamines; Phenylisopropyladenosine; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Theophylline; Vasoconstriction; Vasodilation | 1996 |
Functional classification of P1-purinoceptors in guinea-pig left and right atria: anomalous characteristics of antagonism by cyclopentyltheophylline.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Guinea Pigs; Heart Atria; Heart Rate; In Vitro Techniques; Male; Myocardial Contraction; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Theophylline | 1997 |
Adenosine receptor mediates motility in human melanoma cells.
Topics: Adenosine; Adenosine Monophosphate; Animals; Chemotaxis; CHO Cells; Cricetinae; Dose-Response Relationship, Drug; Humans; Melanoma, Experimental; Pertussis Toxin; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Transfection; Virulence Factors, Bordetella; Xanthines | 1998 |
Decreased presynaptic sensitivity to adenosine after cocaine withdrawal.
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adenosine; Affinity Labels; Animals; Cocaine; Dipyridamole; Dopamine Uptake Inhibitors; Excitatory Postsynaptic Potentials; Glutamic Acid; Hippocampus; Male; Nucleus Accumbens; Phosphodiesterase Inhibitors; Presynaptic Terminals; Purinergic P1 Receptor Agonists; Rats; Rats, Sprague-Dawley; Stimulation, Chemical; Substance Withdrawal Syndrome; Substance-Related Disorders; Theophylline; Thioinosine; Vasodilator Agents; Xanthines | 1998 |
Endogenous adenosine protects CA1 neurons from kainic acid-induced neuronal cell loss in the rat hippocampus.
Topics: Adenosine; Animals; Apoptosis; Disease Models, Animal; Excitatory Amino Acid Agonists; Glial Fibrillary Acidic Protein; Hippocampus; Histocompatibility Antigens Class II; Injections, Intraventricular; Kainic Acid; Macrophage-1 Antigen; Male; Microtubule-Associated Proteins; Nerve Degeneration; Neuroglia; Neurons; Phosphorylation; Proto-Oncogene Proteins c-jun; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptors, Purinergic P1; Theophylline | 1999 |
Saturation of neuroprotective effects of adenosine in cortical culture.
Topics: Adenosine; Animals; Cell Culture Techniques; Cell Death; Cerebral Cortex; Excitatory Amino Acid Agonists; Extracellular Space; Glucose; Hypoxia; Mice; N-Methylaspartate; Neurons; Neuroprotective Agents; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Theophylline | 2002 |
Involvement of adenosine A1 and A2A receptors in the motor effects of caffeine after its acute and chronic administration.
Topics: Adenosine; Amphetamine; Animals; Behavior, Animal; Caffeine; Central Nervous System Stimulants; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Male; Motor Activity; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A2A; Receptors, Purinergic P1; Theophylline; Time Factors; Triazines; Triazoles; Tritium; Xanthines | 2003 |
Adenosine A(1) receptor-mediated presynaptic inhibition at the calyx of Held of immature rats.
Topics: Adenosine; Animals; Auditory Pathways; Baclofen; Blotting, Western; Brain Stem; Calcium; Calcium Channels; Dose-Response Relationship, Drug; Excitatory Postsynaptic Potentials; GABA-B Receptor Agonists; Gene Expression Regulation, Developmental; Immunohistochemistry; Neural Inhibition; omega-Conotoxin GVIA; Patch-Clamp Techniques; Potassium; Potassium Channels; Presynaptic Terminals; Rats; Rats, Wistar; Receptor, Adenosine A1; Receptors, Presynaptic; Synaptophysin; Tetrodotoxin; Theophylline | 2003 |
Involvement of adenosine A1 and A2A receptors in the adenosinergic modulation of the discriminative-stimulus effects of cocaine and methamphetamine in rats.
Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Animals; Central Nervous System Stimulants; Cocaine; Conditioning, Operant; Discrimination Learning; Discrimination, Psychological; Dose-Response Relationship, Drug; Generalization, Psychological; Male; Methamphetamine; Phenethylamines; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A1; Receptor, Adenosine A2A; Theophylline; Xanthines | 2003 |
The role of intraspinal adenosine A1 receptors in sympathetic regulation.
Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Adenosine A3 Receptor Agonists; Adenosine A3 Receptor Antagonists; Adenosine-5'-(N-ethylcarboxamide); Animals; Dihydropyridines; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A1; Spinal Cord; Splanchnic Nerves; Sympathetic Nervous System; Synaptic Transmission; Theobromine; Theophylline; Triazines; Triazoles | 2004 |
Spinal vs. supraspinal antinociceptive activity of the adenosine A(1) receptor agonist cyclopentyl-adenosine in rats with inflammation.
Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Analgesics; Animals; Blood Pressure; Dose-Response Relationship, Drug; Electric Stimulation; Evoked Potentials, Motor; Female; Hyperalgesia; In Vitro Techniques; Inflammation; Male; Rats; Rats, Wistar; Receptor, Adenosine A1; Reflex, Monosynaptic; Spinal Cord; Spinal Nerve Roots; Stress, Mechanical; Theophylline | 2004 |
Adenosine A(1)-receptor-mediated tonic inhibition of glutamate release at rat hippocampal CA3-CA1 synapses is primarily due to inhibition of N-type Ca(2+) channels.
Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Animals; Calcium Channel Blockers; Calcium Channels, N-Type; Dose-Response Relationship, Drug; Glutamic Acid; Hippocampus; In Vitro Techniques; Male; omega-Agatoxin IVA; omega-Conotoxin GVIA; Rats; Rats, Wistar; Receptor, Adenosine A1; Synapses; Synaptic Transmission; Theophylline | 2004 |
Role of central and peripheral adenosine receptors in the cardiovascular responses to intraperitoneal injections of adenosine A1 and A2A subtype receptor agonists.
Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Animals; Blood Pressure; Caffeine; Heart Rate; Injections, Intraperitoneal; Male; Phenethylamines; Rats; Rats, Sprague-Dawley; Theophylline; Xanthines | 2005 |
A "locked-on," constitutively active mutant of the adenosine A1 receptor.
Topics: Adenosine; Animals; Binding, Competitive; Cell Line; Cell Membrane; Chlorocebus aethiops; Colforsin; COS Cells; Cyclic AMP; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Humans; Kinetics; Mutation; Plasmids; Radioligand Assay; Receptor, Adenosine A1; Sodium; Sulfur Radioisotopes; Theophylline; Thiophenes; Transfection; Tritium; Xanthines | 2005 |
The role of adenosine A(1) receptors in the interaction between amygdala and entorhinal cortex of kindled rats.
Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Amygdala; Analysis of Variance; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Entorhinal Cortex; Kindling, Neurologic; Male; Microinjections; Rats; Rats, Sprague-Dawley; Reaction Time; Receptor, Adenosine A1; Seizures; Time Factors; Xanthines | 2005 |
Contribution of adenosine receptors in the control of arteriolar tone and adenosine-angiotensin II interaction.
Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Angiotensin II; Animals; Arterioles; Feedback; Female; Kidney Glomerulus; Kidney Tubules; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Phenethylamines; Purines; Receptor, Adenosine A1; Receptors, Adenosine A2; Theophylline; Triazines; Triazoles; Vasoconstriction; Vasodilation | 2006 |
Intra-VTA adenosine A1 receptor activation blocks morphine stimulation of motor behavior and cortical and limbic Fos immunoreactivity.
Topics: Adenosine; Adenosine A1 Receptor Agonists; Animals; Biomarkers; Cerebral Cortex; Dose-Response Relationship, Drug; Gene Expression Regulation; Limbic System; Male; Mice; Mice, Inbred C57BL; Morphine; Motor Activity; Neurons; Nucleus Accumbens; Proto-Oncogene Proteins c-fos; Theophylline; Ventral Tegmental Area | 2009 |