Page last updated: 2024-09-03

8-chloro-4-methyl-1,2,3,4,4a,5,6,10b-octahydrobenzo(f)quinolin-3(2h)-one and finasteride

8-chloro-4-methyl-1,2,3,4,4a,5,6,10b-octahydrobenzo(f)quinolin-3(2h)-one has been researched along with finasteride in 1 studies

Compound Research Comparison

Studies
(8-chloro-4-methyl-1,2,3,4,4a,5,6,10b-octahydrobenzo(f)quinolin-3(2h)-one)
Trials
(8-chloro-4-methyl-1,2,3,4,4a,5,6,10b-octahydrobenzo(f)quinolin-3(2h)-one)
Recent Studies (post-2010)
(8-chloro-4-methyl-1,2,3,4,4a,5,6,10b-octahydrobenzo(f)quinolin-3(2h)-one)
Studies
(finasteride)
Trials
(finasteride)
Recent Studies (post-2010) (finasteride)
7002,514405867

Protein Interaction Comparison

ProteinTaxonomy8-chloro-4-methyl-1,2,3,4,4a,5,6,10b-octahydrobenzo(f)quinolin-3(2h)-one (IC50)finasteride (IC50)
Cytochrome P450 2C9 Homo sapiens (human)2
3-oxo-5-alpha-steroid 4-dehydrogenase 1Homo sapiens (human)0.295
3-oxo-5-alpha-steroid 4-dehydrogenase 1 Rattus norvegicus (Norway rat)0.0109
3-oxo-5-alpha-steroid 4-dehydrogenase 2Homo sapiens (human)0.0131
3-oxo-5-alpha-steroid 4-dehydrogenase 2Rattus norvegicus (Norway rat)0.3286
Cytochrome P450 2C19Homo sapiens (human)1

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Andersson, S; Audia, JE; Hirsch, KS; Jones, CD; McQuaid, L; Neubauer, BL; Pennington, P; Russell, DW; Stamm, NB; Toomey, RE1

Other Studies

1 other study(ies) available for 8-chloro-4-methyl-1,2,3,4,4a,5,6,10b-octahydrobenzo(f)quinolin-3(2h)-one and finasteride

ArticleYear
LY191704: a selective, nonsteroidal inhibitor of human steroid 5 alpha-reductase type 1.
    Proceedings of the National Academy of Sciences of the United States of America, 1993, Jun-01, Volume: 90, Issue:11

    Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; 5-alpha Reductase Inhibitors; Androstenes; Animals; Azasteroids; Cell Line; Finasteride; Humans; Isoenzymes; Kinetics; Male; Prostate; Quinolones; Rats; Skin; Transfection

1993