8-chloro-4-methyl-1,2,3,4,4a,5,6,10b-octahydrobenzo(f)quinolin-3(2h)-one and dihydrotestosterone

8-chloro-4-methyl-1,2,3,4,4a,5,6,10b-octahydrobenzo(f)quinolin-3(2h)-one has been researched along with dihydrotestosterone in 2 studies

Compound Research Comparison

Studies (8-chloro-4-methyl-1,2,3,4,4a,5,6,10b-octahydrobenzo(f)quinolin-3(2h)-one)	Trials (8-chloro-4-methyl-1,2,3,4,4a,5,6,10b-octahydrobenzo(f)quinolin-3(2h)-one)	Recent Studies (post-2010) (8-chloro-4-methyl-1,2,3,4,4a,5,6,10b-octahydrobenzo(f)quinolin-3(2h)-one)	Studies (dihydrotestosterone)	Trials (dihydrotestosterone)	Recent Studies (post-2010) (dihydrotestosterone)
7	0	0	9,325	307	1,517

Protein Interaction Comparison

Protein	Taxonomy	dihydrotestosterone (IC50)
Plasma kallikrein	Homo sapiens (human)	0.0031
Glucocorticoid receptor	Homo sapiens (human)	0.54
Sex hormone-binding globulin	Homo sapiens (human)	0.0038
Progesterone receptor	Oryctolagus cuniculus (rabbit)	0.44
Progesterone receptor	Homo sapiens (human)	7.3
Mineralocorticoid receptor	Homo sapiens (human)	0.36
Sex hormone-binding globulin	Rattus norvegicus (Norway rat)	0.023
Androgen receptor	Homo sapiens (human)	0.0048
Androgen receptor	Rattus norvegicus (Norway rat)	0.4041
Androgen receptor	Mus musculus (house mouse)	0.001
Mineralocorticoid receptor	Rattus norvegicus (Norway rat)	2.1
Testosterone 17-beta-dehydrogenase 3	Homo sapiens (human)	0.0026

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	1 (50.00)	18.2507
2000's	1 (50.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Audia, JE; Gray, HM; Hanke, CW; Hirsch, KS; Hsiao, KC; Jones, CD; Kumar, MV; Lawhorn, DE; Lindzey, J; McQuaid, L; Neubauer, BL; Tindall, DJ; Toomey, RE; Yao, RC	1
Feix, M; Issa, S; Russell, DW; Schaefer, HE; Schnabel, D; Schweikert, HU; Wolf, L	1

Other Studies

2 other study(ies) available for 8-chloro-4-methyl-1,2,3,4,4a,5,6,10b-octahydrobenzo(f)quinolin-3(2h)-one and dihydrotestosterone

Article	Year
LY191704 inhibits type I steroid 5 alpha-reductase in human scalp. The Journal of clinical endocrinology and metabolism, 1996, Volume: 81, Issue:6 Topics: 5-alpha Reductase Inhibitors; Animals; Binding, Competitive; Dihydrotestosterone; Humans; Isoenzymes; Male; Mice; Osmolar Concentration; Quinolones; Scalp	1996
Human osteoblast-like cells express predominantly steroid 5alpha-reductase type 1. The Journal of clinical endocrinology and metabolism, 2002, Volume: 87, Issue:12 Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; 5-alpha Reductase Inhibitors; Aged; Aged, 80 and over; Azasteroids; Cells, Cultured; Dihydrotestosterone; Enzyme Inhibitors; Female; Humans; Isoenzymes; Male; Middle Aged; Osteoblasts; Quinolones; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger	2002

Article

Year

LY191704 inhibits type I steroid 5 alpha-reductase in human scalp.

The Journal of clinical endocrinology and metabolism, 1996, Volume: 81, Issue:6

Topics: 5-alpha Reductase Inhibitors; Animals; Binding, Competitive; Dihydrotestosterone; Humans; Isoenzymes; Male; Mice; Osmolar Concentration; Quinolones; Scalp

1996

Human osteoblast-like cells express predominantly steroid 5alpha-reductase type 1.

The Journal of clinical endocrinology and metabolism, 2002, Volume: 87, Issue:12

Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; 5-alpha Reductase Inhibitors; Aged; Aged, 80 and over; Azasteroids; Cells, Cultured; Dihydrotestosterone; Enzyme Inhibitors; Female; Humans; Isoenzymes; Male; Middle Aged; Osteoblasts; Quinolones; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger

2002