8-chloro-4-methyl-1,2,3,4,4a,5,6,10b-octahydrobenzo(f)quinolin-3(2h)-one has been researched along with carbostyril in 7 studies
| Studies (8-chloro-4-methyl-1,2,3,4,4a,5,6,10b-octahydrobenzo(f)quinolin-3(2h)-one) | Trials (8-chloro-4-methyl-1,2,3,4,4a,5,6,10b-octahydrobenzo(f)quinolin-3(2h)-one) | Recent Studies (post-2010) (8-chloro-4-methyl-1,2,3,4,4a,5,6,10b-octahydrobenzo(f)quinolin-3(2h)-one) | Studies (carbostyril) | Trials (carbostyril) | Recent Studies (post-2010) (carbostyril) |
|---|---|---|---|---|---|
| 7 | 0 | 0 | 12,855 | 1,323 | 5,611 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (57.14) | 18.2507 |
| 2000's | 3 (42.86) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Andersson, S; Audia, JE; Hirsch, KS; Jones, CD; McQuaid, L; Neubauer, BL; Pennington, P; Russell, DW; Stamm, NB; Toomey, RE | 1 |
| Coleman, NL; Farid, NA; Schreiner, KM; Van Lier, RB; Wrighton, SA | 1 |
| Audia, JE; Gray, HM; Hanke, CW; Hirsch, KS; Hsiao, KC; Jones, CD; Kumar, MV; Lawhorn, DE; Lindzey, J; McQuaid, L; Neubauer, BL; Tindall, DJ; Toomey, RE; Yao, RC | 1 |
| Coleman, NL; Farid, NA | 1 |
| Comerci, A; Danza, G; Guarna, A; Mancina, R; Occhiato, EG; Scarpi, D; Serio, M; Zorn, C | 1 |
| Feix, M; Issa, S; Russell, DW; Schaefer, HE; Schnabel, D; Schweikert, HU; Wolf, L | 1 |
| Makrantonaki, E; Zouboulis, CC | 1 |
7 other study(ies) available for 8-chloro-4-methyl-1,2,3,4,4a,5,6,10b-octahydrobenzo(f)quinolin-3(2h)-one and carbostyril
| Article | Year |
|---|---|
LY191704: a selective, nonsteroidal inhibitor of human steroid 5 alpha-reductase type 1.
Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; 5-alpha Reductase Inhibitors; Androstenes; Animals; Azasteroids; Cell Line; Finasteride; Humans; Isoenzymes; Kinetics; Male; Prostate; Quinolones; Rats; Skin; Transfection | 1993 |
Stereoselective disposition of the enantiomers of the benzoquinolinone LY191704, a human type I 5 alpha-reductase inhibitor. Differences between rats and dogs.
Topics: 5-alpha Reductase Inhibitors; Animals; Dogs; Enzyme Inhibitors; Humans; Male; Microsomes, Liver; Quinolones; Rats; Rats, Inbred F344; Species Specificity; Stereoisomerism | 1996 |
LY191704 inhibits type I steroid 5 alpha-reductase in human scalp.
Topics: 5-alpha Reductase Inhibitors; Animals; Binding, Competitive; Dihydrotestosterone; Humans; Isoenzymes; Male; Mice; Osmolar Concentration; Quinolones; Scalp | 1996 |
High-performance liquid chromatographic determination of the enantiomers of the benzoquinolinone LY191704, a human type 1 5 alpha-reductase inhibitor, in plasma.
Topics: 5-alpha Reductase Inhibitors; Animals; Chromatography, High Pressure Liquid; Dogs; Enzyme Inhibitors; Humans; Quality Control; Quinolones; Rats; Sensitivity and Specificity; Species Specificity; Stereoisomerism | 1997 |
Synthesis of 8-chloro-benzo[c]quinolizin-3-ones as potent and selective inhibitors of human steroid 5alpha-reductase 1.
Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; 5-alpha Reductase Inhibitors; Anti-Inflammatory Agents, Non-Steroidal; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Quinolizines; Quinolones; Sensitivity and Specificity; Structure-Activity Relationship; Titanium | 2000 |
Human osteoblast-like cells express predominantly steroid 5alpha-reductase type 1.
Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; 5-alpha Reductase Inhibitors; Aged; Aged, 80 and over; Azasteroids; Cells, Cultured; Dihydrotestosterone; Enzyme Inhibitors; Female; Humans; Isoenzymes; Male; Middle Aged; Osteoblasts; Quinolones; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2002 |
Testosterone metabolism to 5alpha-dihydrotestosterone and synthesis of sebaceous lipids is regulated by the peroxisome proliferator-activated receptor ligand linoleic acid in human sebocytes.
Topics: 17-Ketosteroids; 5-alpha Reductase Inhibitors; Androstanols; Cell Proliferation; Cells, Cultured; Drug Synergism; Humans; Ligands; Linoleic Acid; Lipids; Peroxisome Proliferator-Activated Receptors; Quinolones; Sebaceous Glands; Testosterone | 2007 |