8-bromo-2--deoxyguanosine and 5--deoxy-5--iodouridine

8-bromo-2--deoxyguanosine has been researched along with 5--deoxy-5--iodouridine* in 1 studies

Other Studies

1 other study(ies) available for 8-bromo-2--deoxyguanosine and 5--deoxy-5--iodouridine

Article	Year
Aqueous-phase Sonogashira alkynylation to synthesize 5-substituted pyrimidine and 8-substituted purine nucleosides. Current protocols in nucleic acid chemistry, 2012, Volume: Chapter 1 In this unit, an efficient method for the synthesis of alkyne-modified nucleosides in an aqueous solvent system is described. The method allows direct palladium-catalyzed alkynylation of readily available unprotected 8-bromo-2'-deoxyguanosine (8-BrdG), 8-bromo-2'-deoxyadenosene (8-BrdA), 8-bromoadenosine (8-BrA), and 5-iodo-2'-deoxyuridine (5-IdU) precursors. The optimal catalyst is derived from palladium acetate, tri-(2,4-dimethyl-5-sulfonatophenyl)phosphane (TXPTS), and CuI. Topics: Alkynes; Benzenesulfonates; Catalysis; Copper; Deoxyguanosine; Idoxuridine; Iodides; Models, Molecular; Palladium; Phosphines; Purine Nucleosides; Pyrimidine Nucleosides	2012

Article

Year

Aqueous-phase Sonogashira alkynylation to synthesize 5-substituted pyrimidine and 8-substituted purine nucleosides.

Current protocols in nucleic acid chemistry, 2012, Volume: Chapter 1

In this unit, an efficient method for the synthesis of alkyne-modified nucleosides in an aqueous solvent system is described. The method allows direct palladium-catalyzed alkynylation of readily available unprotected 8-bromo-2'-deoxyguanosine (8-BrdG), 8-bromo-2'-deoxyadenosene (8-BrdA), 8-bromoadenosine (8-BrA), and 5-iodo-2'-deoxyuridine (5-IdU) precursors. The optimal catalyst is derived from palladium acetate, tri-(2,4-dimethyl-5-sulfonatophenyl)phosphane (TXPTS), and CuI.

Topics: Alkynes; Benzenesulfonates; Catalysis; Copper; Deoxyguanosine; Idoxuridine; Iodides; Models, Molecular; Palladium; Phosphines; Purine Nucleosides; Pyrimidine Nucleosides

2012