Page last updated: 2024-09-03

8-azidoadenosine diphosphate and vanadates

8-azidoadenosine diphosphate has been researched along with vanadates in 8 studies

Compound Research Comparison

Studies
(8-azidoadenosine diphosphate)
Trials
(8-azidoadenosine diphosphate)
Recent Studies (post-2010)
(8-azidoadenosine diphosphate)
Studies
(vanadates)
Trials
(vanadates)
Recent Studies (post-2010) (vanadates)
31005,2007785

Protein Interaction Comparison

ProteinTaxonomy8-azidoadenosine diphosphate (IC50)vanadates (IC50)
Tyrosine-protein phosphatase non-receptor type 1Homo sapiens (human)0.0254

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's8 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ambudkar, SV; Sauna, ZE1
Gimi, K; Senior, AE; Urbatsch, IL; Wilke-Mounts, S1
Ambudkar, SV; Kerr, KM; Sauna, ZE1
Ambudkar, SV; Muller, M; Sauna, ZE; Smith, MM1
Cole, SP; Deeley, RG; Leslie, EM; Mao, Q; Oleschuk, CJ1
Basso, C; Gadsby, DC; Nairn, AC; Vergani, P1
Cole, SP; Conseil, G; Deeley, RG1
Dey, S; Ghosh, P; Maki, N; Moitra, K1

Other Studies

8 other study(ies) available for 8-azidoadenosine diphosphate and vanadates

ArticleYear
Evidence for a requirement for ATP hydrolysis at two distinct steps during a single turnover of the catalytic cycle of human P-glycoprotein.
    Proceedings of the National Academy of Sciences of the United States of America, 2000, Mar-14, Volume: 97, Issue:6

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Adenylyl Imidodiphosphate; ATP Binding Cassette Transporter, Subfamily B, Member 1; Azides; Cell Membrane; DNA, Complementary; Genes, MDR; Humans; Hydrolysis; Kinetics; Models, Biological; Photoaffinity Labels; Protein Binding; Protein Conformation; Time Factors; Vanadates

2000
Investigation of the role of glutamine-471 and glutamine-1114 in the two catalytic sites of P-glycoprotein.
    Biochemistry, 2000, Oct-03, Volume: 39, Issue:39

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Aluminum; Animals; ATP Binding Cassette Transporter, Subfamily B; ATP-Binding Cassette Transporters; Azides; Beryllium; Binding, Competitive; Ca(2+) Mg(2+)-ATPase; Catalytic Domain; Enzyme Activation; Enzyme Inhibitors; Fluorides; Fluorine; Glutamine; Magnesium; Mice; Mutagenesis, Site-Directed; Photoaffinity Labels; Recombinant Proteins; Vanadates

2000
Correlation between steady-state ATP hydrolysis and vanadate-induced ADP trapping in Human P-glycoprotein. Evidence for ADP release as the rate-limiting step in the catalytic cycle and its modulation by substrates.
    The Journal of biological chemistry, 2001, Mar-23, Volume: 276, Issue:12

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; ATP Binding Cassette Transporter, Subfamily B, Member 1; Azides; Catalysis; Humans; Hydrolysis; Kinetics; Vanadates

2001
Functionally similar vanadate-induced 8-azidoadenosine 5'-[alpha-(32)P]Diphosphate-trapped transition state intermediates of human P-glycoprotin are generated in the absence and presence of ATP hydrolysis.
    The Journal of biological chemistry, 2001, Jun-15, Volume: 276, Issue:24

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Affinity Labels; Animals; ATP Binding Cassette Transporter, Subfamily B; Azides; Binding Sites; Cell Line; Cell Membrane; HeLa Cells; Humans; Hydrolysis; Insecta; Kinetics; Phosphorus Radioisotopes; Recombinant Proteins; Thermodynamics; Transfection; Vanadates

2001
Modulation of multidrug resistance protein 1 (MRP1/ABCC1) transport and atpase activities by interaction with dietary flavonoids.
    Molecular pharmacology, 2001, Volume: 59, Issue:5

    Topics: Adenosine Diphosphate; Adenosine Triphosphatases; Antineoplastic Agents, Phytogenic; ATP-Binding Cassette Transporters; Azides; Binding, Competitive; Biological Transport; Cell Division; Chromatography, High Pressure Liquid; Drug Interactions; Estradiol; Estrogen Antagonists; Flavanones; Flavonoids; Glutathione; HeLa Cells; Humans; Kaempferols; Kinetics; Leukotriene C4; Multidrug Resistance-Associated Proteins; Phosphorus Radioisotopes; Quercetin; Transfection; Tritium; Vanadates; Vincristine

2001
Prolonged nonhydrolytic interaction of nucleotide with CFTR's NH2-terminal nucleotide binding domain and its role in channel gating.
    The Journal of general physiology, 2003, Volume: 122, Issue:3

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Alanine; Animals; Azides; Cell Line; Chloride Channels; Cystic Fibrosis Transmembrane Conductance Regulator; Humans; Ion Channel Gating; Kinetics; Lysine; Mutation; Oocytes; Osmolar Concentration; Peptide Fragments; Phosphorylation; Protein Isoforms; Protein Structure, Tertiary; Temperature; Time Factors; Vanadates; Xenopus laevis

2003
Functional importance of three basic residues clustered at the cytosolic interface of transmembrane helix 15 in the multidrug and organic anion transporter MRP1 (ABCC1).
    The Journal of biological chemistry, 2006, Jan-06, Volume: 281, Issue:1

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Amino Acid Sequence; Arginine; Azides; Catalytic Domain; Cell Line; Cytosol; Estradiol; Humans; Kidney; Leukotriene C4; Lysine; Molecular Sequence Data; Multidrug Resistance-Associated Proteins; Mutagenesis, Site-Directed; Phosphorus Radioisotopes; Protein Structure, Secondary; Protein Structure, Tertiary; Structure-Activity Relationship; Tritium; Vanadates

2006
Allosteric modulation bypasses the requirement for ATP hydrolysis in regenerating low affinity transition state conformation of human P-glycoprotein.
    The Journal of biological chemistry, 2006, Apr-21, Volume: 281, Issue:16

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Allosteric Site; Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Azides; Binding Sites; Catalytic Domain; Cell Line; Cell Membrane; Flupenthixol; Humans; Hydrolysis; Insecta; Ligands; Molecular Conformation; Prazosin; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Thioxanthenes; Time Factors; Trypsin; Vanadates

2006