Compounds > 8-aminoquinoline
Page last updated: 2024-08-21

8-aminoquinoline and chloroquine

8-aminoquinoline has been researched along with chloroquine in 9 studies

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19901 (11.11)18.7374
1990's0 (0.00)18.2507
2000's3 (33.33)29.6817
2010's3 (33.33)24.3611
2020's2 (22.22)2.80

Authors

AuthorsStudies
Egan, TJ; Hunter, R; Kaschula, CH; Marques, HM; Misplon, A; Walden, J1
Catisti, R; Docampo, R; Rodrigues, CO; Vercesi, AE1
ALVING, AS; BREWER, GJ; CARSON, PE; JOHNSON, CF; KELLERMEYER, RW; TARLOV, AR1
Castanys, S; Castanys-Muñoz, E; Gamarro, F; Pérez-Victoria, JM1
Amnuaysirikul, J; Caridha, D; Gao, X; Grogl, M; Hickman, M; Ishida, H; Li, Q; Magill, AJ; O'Neil, MT; Ohrt, C; Ray, P; Weina, PJ; Zhang, P1
Baresel, PC; Campo, B; Magill, AJ; Ohrt, C; Rochford, R; Sampath, A; Tekwani, BL; Walker, LA1
Chandra, S; Kumari, M; Subbarao, N; Tiwari, N1
Andolina, C; Awuku, NA; Bifani, P; Campo, B; Chaumeau, V; Chhin, C; Chua, ACY; Conway, AJ; Cooper, CA; Doeurk, B; Jiang, RHY; Kim, S; Kittiphanakun, P; Kyle, DE; Maher, SP; Nosten, F; Ouk, S; Péneau, J; Phal, S; Phen, S; Piv, E; Rizopoulos, Z; Rouillier, M; Russell, B; Suriyakan, S; Tat, B; Vantaux, A; Vong, C; Witkowski, B1
Shanks, GD1

Other Studies

9 other study(ies) available for 8-aminoquinoline and chloroquine

ArticleYear
Structure-function relationships in aminoquinolines: effect of amino and chloro groups on quinoline-hematin complex formation, inhibition of beta-hematin formation, and antiplasmodial activity.
    Journal of medicinal chemistry, 2000, Jan-27, Volume: 43, Issue:2

    Topics: Aminoquinolines; Animals; Antimalarials; Hemin; Magnetic Resonance Spectroscopy; Mass Spectrometry; Plasmodium falciparum; Structure-Activity Relationship

2000
Presence of a Na(+)/H(+) exchanger in acidocalcisomes of Leishmania donovani and their alkalization by anti-leishmanial drugs.
    FEBS letters, 2000, May-12, Volume: 473, Issue:2

    Topics: Acridine Orange; Adenosine Triphosphate; Aminoquinolines; Ammonium Chloride; Animals; Antiprotozoal Agents; Butylated Hydroxytoluene; Chloroquine; Hydrogen-Ion Concentration; Leishmania donovani; Pentamidine; Sodium Chloride; Sodium-Hydrogen Exchangers; Vacuoles

2000
Mitigation of the haemolytic effect of primaquine and enhancement of its action against exoerythrocytic forms of the Chesson strain of Piasmodium vivax by intermittent regimens of drug administration: a preliminary report.
    Bulletin of the World Health Organization, 1960, Volume: 22

    Topics: Adult; Aminoquinolines; Antimalarials; Chloroquine; Hemolysis; Humans; Malaria, Vivax; Male; Primaquine

1960
Characterization of an ABCG-like transporter from the protozoan parasite Leishmania with a role in drug resistance and transbilayer lipid movement.
    Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:10

    Topics: Aminoquinolines; Animals; Antiprotozoal Agents; ATP-Binding Cassette Transporters; Base Sequence; Biological Transport, Active; Chloroquine; DNA, Protozoan; Drug Resistance; Fluorescent Dyes; Genes, Protozoan; Humans; Leishmania infantum; Leishmaniasis, Visceral; Lipid Bilayers; Phosphorylcholine; Protozoan Proteins; Recombinant Proteins; Transformation, Genetic

2008
An in vivo drug screening model using glucose-6-phosphate dehydrogenase deficient mice to predict the hemolytic toxicity of 8-aminoquinolines.
    The American journal of tropical medicine and hygiene, 2013, Volume: 88, Issue:6

    Topics: Acute Disease; Aminoquinolines; Anemia, Hemolytic; Animals; Antimalarials; Chloroquine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Genotype; Glucosephosphate Dehydrogenase Deficiency; Glutathione; Haptoglobins; Hemolytic Agents; Male; Mefloquine; Mice; Phenotype; Primaquine; Reticulocyte Count

2013
Humanized mouse model of glucose 6-phosphate dehydrogenase deficiency for in vivo assessment of hemolytic toxicity.
    Proceedings of the National Academy of Sciences of the United States of America, 2013, Oct-22, Volume: 110, Issue:43

    Topics: Aminoquinolines; Anemia, Hemolytic; Animals; Antimalarials; Chloroquine; Combined Modality Therapy; Dapsone; Dose-Response Relationship, Drug; Doxycycline; Drug Evaluation, Preclinical; Erythrocyte Count; Erythrocyte Transfusion; Female; Glucosephosphate Dehydrogenase Deficiency; Humans; Mefloquine; Mice; Mice, Inbred NOD; Mice, SCID; Primaquine; Pyrimethamine; Reproducibility of Results; Sensitivity and Specificity; Transplantation, Heterologous

2013
3D QSAR, pharmacophore and molecular docking studies of known inhibitors and designing of novel inhibitors for M18 aspartyl aminopeptidase of Plasmodium falciparum.
    BMC structural biology, 2016, 08-17, Volume: 16

    Topics: Aminoquinolines; Antimalarials; Chloroquine; Drug Design; Glutamyl Aminopeptidase; Humans; Malaria, Falciparum; Molecular Docking Simulation; Plasmodium falciparum; Quantitative Structure-Activity Relationship

2016
Probing the distinct chemosensitivity of Plasmodium vivax liver stage parasites and demonstration of 8-aminoquinoline radical cure activity in vitro.
    Scientific reports, 2021, 10-07, Volume: 11, Issue:1

    Topics: Aminoquinolines; Antimalarials; Chloroquine; Dose-Response Relationship, Drug; Drug Discovery; Drug Synergism; Humans; Life Cycle Stages; Liver; Malaria, Vivax; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium vivax; ROC Curve; Time Factors

2021
Historical 8-Aminoquinoline Combinations: Not All Antimalarial Drugs Work Well Together.
    The American journal of tropical medicine and hygiene, 2022, 11-14, Volume: 107, Issue:5

    Topics: Aminoquinolines; Antimalarials; Chloroquine; Hemolysis; Humans; Primaquine; Quinine

2022