Page last updated: 2024-08-26

8-aminoadenosine and adenosine

8-aminoadenosine has been researched along with adenosine in 19 studies

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19901 (5.26)18.7374
1990's1 (5.26)18.2507
2000's6 (31.58)29.6817
2010's11 (57.89)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cristalli, G; Esker, JL; Jacobson, KA; Ji, XD; Melman, N; Olah, ME; Schneller, SW; Secrist, JA; Siddiqi, SM; Tiwari, KN1
Borgognoni, J; Clay, A; Daniels, Z; Dokurno, P; Drysdale, MJ; Foloppe, N; Francis, GL; Graham, CJ; Howes, R; Macias, AT; Massey, AJ; Murray, JB; Parsons, R; Shaw, T; Surgenor, AE; Terry, L; Wang, Y; Williamson, DS; Wood, M1
Abel-Santos, E; Alvarez, Z; Lee, K1
Barbeau, O; Burke, R; Cheeseman, MD; Collins, I; Dobson, S; Jeganathan, F; Jones, AM; Jones, K; Kadi, N; Rowlands, M; van Montfort, RL; Westwood, IM; Workman, P1
Miles, HT; Roy, KB1
Ayres, M; Davies, KM; Gandhi, V; Krett, NL; Ma, C; Nabhan, C; Rosen, ST1
Gandhi, V; Ghias, K; Krett, NL; Ma, C; Platanias, LC; Rosen, ST1
Balakrishnan, K; Gandhi, V; Keating, MJ; Wierda, WG1
Bokil, P; Ganesh, KN; Gourishankar, A; Vysabhattar, R1
Avram, MJ; Gandhi, V; Krett, NL; McBrayer, SK; Qian, J; Raikoff, K; Rosen, ST; Schumacker, PT; Shanmugam, M; Singhal, S1
Frey, JA; Gandhi, V1
Ayres, ML; Dennison, JB; Gandhi, V; Krett, NL; Medeiros, LJ; Neelapu, SS; Qian, J; Rosen, ST; Shanmugam, M1
Eitaki, M; Inanami, O; Matsuda, A; Meike, S; Yamamori, T; Yasui, H1
Ayres, ML; Chen, LS; Gandhi, V; Keating, MJ; Nowak, BJ; Pillai, RN; Shpall, EJ; Thomas, MW1
Frankfurt, O; Platanias, LC1
Feng, G; Gandhi, V; Krett, NL; McBrayer, SK; Qian, J; Rosen, ST; Shanmugam, M; Yarrington, M1
Bargonetti, J; Hoffman, S; Krett, NL; Polotskaia, A; Rosen, ST; Shanmugam, M1
Matsuzaki, Y; Nakahari, T; Nakano, T; Sano, K; Wu, H1
Bargonetti, J; Polotskaia, A; Rosso, M1

Other Studies

19 other study(ies) available for 8-aminoadenosine and adenosine

ArticleYear
Search for new purine- and ribose-modified adenosine analogues as selective agonists and antagonists at adenosine receptors.
    Journal of medicinal chemistry, 1995, Mar-31, Volume: 38, Issue:7

    Topics: Adenosine; Animals; Cell Membrane; CHO Cells; Corpus Striatum; Cricetinae; In Vitro Techniques; Magnetic Resonance Spectroscopy; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Purines; Radioligand Assay; Rats; Recombinant Proteins; Ribose; Structure-Activity Relationship

1995
Novel adenosine-derived inhibitors of 70 kDa heat shock protein, discovered through structure-based design.
    Journal of medicinal chemistry, 2009, Mar-26, Volume: 52, Issue:6

    Topics: Adenosine; Cell Line, Tumor; Crystallography, X-Ray; Drug Design; Fluorescence Polarization Immunoassay; HSP70 Heat-Shock Proteins; Humans; Molecular Structure

2009
Testing nucleoside analogues as inhibitors of Bacillus anthracis spore germination in vitro and in macrophage cell culture.
    Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:12

    Topics: Alanine; Animals; Bacillus anthracis; Cell Line; Guanosine; Macrophages; Mice; Spores, Bacterial; Structure-Activity Relationship; Thionucleosides

2010
Exploiting Protein Conformational Change to Optimize Adenosine-Derived Inhibitors of HSP70.
    Journal of medicinal chemistry, 2016, 05-26, Volume: 59, Issue:10

    Topics: Adenosine; Crystallography, X-Ray; Dose-Response Relationship, Drug; HSP70 Heat-Shock Proteins; Humans; Models, Molecular; Molecular Conformation; Structure-Activity Relationship

2016
Binding isotherms of nucleosides and polynucleotides measured by continuous ultrafiltration at constant volume: a rapid and precise technique.
    Biochemistry, 1982, Jan-05, Volume: 21, Issue:1

    Topics: Adenosine; Dialysis; Hydrogen Bonding; Poly U; Temperature; Thermodynamics; Ultrafiltration

1982
8-amino-adenosine is a potential therapeutic agent for multiple myeloma.
    Molecular cancer therapeutics, 2004, Volume: 3, Issue:11

    Topics: Adenosine; Apoptosis; Caspases; Cell Line, Tumor; DNA; Dose-Response Relationship, Drug; Enzyme Activation; Humans; Molecular Structure; Multiple Myeloma; Phosphorylation; Polyphosphates; RNA

2004
8-Amino-adenosine induces loss of phosphorylation of p38 mitogen-activated protein kinase, extracellular signal-regulated kinase 1/2, and Akt kinase: role in induction of apoptosis in multiple myeloma.
    Molecular cancer therapeutics, 2005, Volume: 4, Issue:4

    Topics: Adenosine; Adenosine Triphosphate; Apoptosis; Cell Line, Tumor; Cell Proliferation; Cell Survival; Flow Cytometry; Humans; Immunoblotting; JNK Mitogen-Activated Protein Kinases; Kinetics; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Multiple Myeloma; Nucleosides; p38 Mitogen-Activated Protein Kinases; Phosphoric Monoester Hydrolases; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Purines; Signal Transduction; Time Factors

2005
Mechanisms of cell death of chronic lymphocytic leukemia lymphocytes by RNA-directed agent, 8-NH2-adenosine.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2005, Sep-15, Volume: 11, Issue:18

    Topics: Adenosine; Adenosine Triphosphate; Adult; Aged; Aged, 80 and over; Apoptosis; Chromatography, High Pressure Liquid; Humans; Immunoblotting; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphocytes; Middle Aged; Myeloid Cell Leukemia Sequence 1 Protein; Neoplasm Proteins; Proteins; Proto-Oncogene Proteins c-bcl-2; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Time Factors; X-Linked Inhibitor of Apoptosis Protein

2005
Property editing of peptide nucleic acids (PNA): gem-dimethyl, cyanuryl and 8-aminoadenine PNAs.
    Nucleic acids symposium series (2004), 2007, Issue:51

    Topics: Adenosine; Base Pairing; Hydrogen Bonding; Nucleic Acid Denaturation; Peptide Nucleic Acids; Triazines

2007
Targeting glucose consumption and autophagy in myeloma with the novel nucleoside analogue 8-aminoadenosine.
    The Journal of biological chemistry, 2009, Sep-25, Volume: 284, Issue:39

    Topics: Adenosine; Adenosine Triphosphate; Autophagy; Cell Line, Tumor; Cell Membrane; Cell Proliferation; Chloroquine; Cytoplasm; Dose-Response Relationship, Drug; Drug Synergism; Glucose; Glucose Transporter Type 1; Glucose Transporter Type 4; Humans; Immunoblotting; Microscopy, Fluorescence; Multiple Myeloma; Time Factors; Tumor Cells, Cultured

2009
8-Amino-adenosine inhibits multiple mechanisms of transcription.
    Molecular cancer therapeutics, 2010, Volume: 9, Issue:1

    Topics: Adenosine; Adenosine Triphosphate; Cell Line, Tumor; Drug Screening Assays, Antitumor; Gene Expression Regulation, Neoplastic; Humans; Intracellular Space; Models, Biological; Phosphorylation; Protein Structure, Tertiary; RNA; RNA Polymerase II; Transcription, Genetic

2010
8-Aminoadenosine inhibits Akt/mTOR and Erk signaling in mantle cell lymphoma.
    Blood, 2010, Dec-16, Volume: 116, Issue:25

    Topics: Adenosine; Apoptosis; Blotting, Western; Cell Cycle; Cell Proliferation; Extracellular Signal-Regulated MAP Kinases; Flow Cytometry; Humans; Lymphoma, Mantle-Cell; Phosphorylation; Protein Biosynthesis; Proto-Oncogene Proteins c-akt; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; TOR Serine-Threonine Kinases; Transcription, Genetic; Tumor Cells, Cultured

2010
8-Aminoadenosine enhances radiation-induced cell death in human lung carcinoma A549 cells.
    Journal of radiation research, 2011, Volume: 52, Issue:4

    Topics: Adenocarcinoma; Adenosine; Adenosine Triphosphate; Apoptosis; Caspase Inhibitors; Cell Death; Cell Line, Tumor; Dose-Response Relationship, Radiation; Humans; Microscopy, Fluorescence; Multiple Myeloma; Peptides; Propidium; Radiation-Sensitizing Agents; Signal Transduction; X-Rays

2011
Multifaceted actions of 8-amino-adenosine kill BCR-ABL positive cells.
    Leukemia & lymphoma, 2012, Volume: 53, Issue:10

    Topics: Adenosine; Adenosine Triphosphate; Antineoplastic Agents; Apoptosis; Benzamides; Cell Proliferation; Cell Survival; Drug Resistance, Neoplasm; Fusion Proteins, bcr-abl; Gene Expression Regulation, Leukemic; Humans; Imatinib Mesylate; K562 Cells; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Piperazines; Protein Kinase Inhibitors; Pyrimidines; Transcription, Genetic

2012
Non-tyrosine kinase inhibitor-targeting of BCR-ABL expressing cells.
    Leukemia & lymphoma, 2012, Volume: 53, Issue:10

    Topics: Adenosine; Fusion Proteins, bcr-abl; Humans; Leukemia, Myelogenous, Chronic, BCR-ABL Positive

2012
Integrative gene expression profiling reveals G6PD-mediated resistance to RNA-directed nucleoside analogues in B-cell neoplasms.
    PloS one, 2012, Volume: 7, Issue:7

    Topics: 2-Chloroadenosine; Adenosine; Cell Line, Tumor; Clinical Trials, Phase I as Topic; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Gene Expression Profiling; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Glucosephosphate Dehydrogenase; Hematologic Neoplasms; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphoma, Mantle-Cell; Multiple Myeloma; Neoplasm Proteins; Pentose Phosphate Pathway; RNA, Neoplasm

2012
8-Amino-adenosine activates p53-independent cell death of metastatic breast cancers.
    Molecular cancer therapeutics, 2012, Volume: 11, Issue:11

    Topics: Adenosine; Antineoplastic Agents; Autophagy; Breast Neoplasms; Caspase Inhibitors; Cell Death; Cell Line, Tumor; Cyclin-Dependent Kinase Inhibitor p21; Doxycycline; Female; Humans; Mutant Proteins; Neoplasm Metastasis; Oligopeptides; Receptors, Estrogen; Signal Transduction; Transcription, Genetic; Tumor Suppressor Protein p53

2012
ATP-association to intrabacterial nanotransportation system in Vibrio cholerae.
    Medical molecular morphology, 2015, Volume: 48, Issue:4

    Topics: 2,4-Dinitrophenol; Adenosine; Adenosine Triphosphate; Biological Transport; Cholera Toxin; Cytoplasm; Humans; Hydrogen-Ion Concentration; Intestine, Small; Microscopy, Immunoelectron; Type II Secretion Systems; Uncoupling Agents; Vibrio cholerae

2015
Homozygous mdm2 SNP309 cancer cells with compromised transcriptional elongation at p53 target genes are sensitive to induction of p53-independent cell death.
    Oncotarget, 2015, Oct-27, Volume: 6, Issue:33

    Topics: Adenosine; Antineoplastic Agents; Blotting, Western; Cell Death; Cell Line, Tumor; Chromatin Immunoprecipitation; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Humans; Neoplasms; Polymorphism, Single Nucleotide; Proto-Oncogene Proteins c-mdm2; Real-Time Polymerase Chain Reaction; Transcriptional Activation; Tumor Suppressor Protein p53

2015