8-(4-sulfophenyl)theophylline has been researched along with adenosine in 217 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 22 (10.14) | 18.7374 |
| 1990's | 126 (58.06) | 18.2507 |
| 2000's | 52 (23.96) | 29.6817 |
| 2010's | 17 (7.83) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| De Koninck, Y; Henry, JL | 1 |
| Späth, L; Starke, K; von Kügelgen, I | 1 |
| Henry, JL; Li, H | 2 |
| Mentzer, RM; Van Wylen, DG; Wang, T | 1 |
| Johnston, WE; McGee, S; Toombs, CF; Vinten-Johansen, J | 1 |
| Baumgold, J; Jacobson, KA; Nikodijevic, O | 1 |
| Miura, K; Okumura, M; Yamamoto, K; Yamashita, Y; Yukimura, T | 1 |
| Hammarström, M; Samuelson, UE; Wiklund, NP | 1 |
| DeLuca, B; Jovetich, M; Middlemiss, PJ; Rathbone, MP | 1 |
| Bjur, RA; Forsyth, KM; Westfall, DP | 1 |
| Bailey, SJ; Hourani, SM; Kitchen, I; Nicholls, J | 1 |
| Holtzman, SG; Mumford, GK | 1 |
| Dole, WP; Heller, LJ; Mohrman, DE | 1 |
| Brackett, LE; Daly, JW | 1 |
| Martin, SE; Patterson, RE; Tidmore, WC | 1 |
| Downey, JM; Liu, GS; Olsson, RA; Stanley, AW; Thornton, J; Van Winkle, DM | 1 |
| Heller, LJ; Trachte, GJ | 1 |
| Cronstein, BN; Salmon, JE | 1 |
| Marangos, PJ; von Lubitz, DK | 1 |
| Dar, MS | 1 |
| Berman, RF; Lupica, CR; Rosen, JB; Whitcomb, K | 1 |
| Phillis, JW | 1 |
| Fowler, JC | 1 |
| Gustafsson, LE; Hedqvist, P; Lindbom, L; Ohlén, A; Persson, MG | 1 |
| Bonifacj, JF; Hasni, H; Laborit, H | 1 |
| Franklin, PH; Murray, TF; Zhang, G | 2 |
| Linden, J; Munshi, R | 1 |
| Cederqvist, B; Gustafsson, LE; Wiklund, NP | 1 |
| Crone, C; Fuglsang, A; Therkildsen, P | 1 |
| Heller, LJ; Regal, JF; Trachte, GJ | 1 |
| Durcan, MJ; Morgan, PF | 1 |
| Berne, RM; Park, TS; Rubio, R; Van Wylen, DG | 2 |
| Gustafsson, LE; Wiklund, NP | 1 |
| Cronstein, BN; Hirschhorn, R; Rose, FR; Weissmann, G | 1 |
| Birch, BD; Gaba, DM; Louie, GL; Maze, M; Vickery, RG | 1 |
| Geiger, JD; Westerberg, VS | 1 |
| Gustafsson, LE; Samuelson, UE; Wiklund, NP | 1 |
| Heller, LJ; Olsson, RA | 1 |
| Bjur, RA; Shinozuka, K; Westfall, DP | 1 |
| Fredholm, BB; Hedqvist, P; Wennmalm, M | 1 |
| Henry, JL; Salter, MW | 1 |
| Evoniuk, G; von Borstel, RW; Wurtman, RJ | 1 |
| Kenakin, TP; Pike, NB | 1 |
| Vertes, RP; Wu, PH | 1 |
| Gustafsson, LE | 1 |
| Cook, DA; Krueger, CA | 1 |
| Ansell, J; Cassidy, J; Czernik, AJ; Petrack, B | 1 |
| Armstrong, S; Downey, JM; Ganote, CE | 2 |
| Burnstock, G; Vials, AJ | 2 |
| Armstrong, S; Ganote, CE | 1 |
| Burnstock, G; Ralevic, V; Rubino, A | 1 |
| Hollingsworth, M; Piper, AS | 1 |
| Roth, S | 1 |
| Chilian, WM; DeFily, DV; Patterson, JL | 1 |
| Arora, CP; Castro, LC; Koos, BJ; Mason, BA; Ogunyemi, DA | 1 |
| Downey, HF; Fan, WL; Gao, ZP; Mallet, RT | 1 |
| Hargittai, PT; Lieberman, EA; Mustafa, SJ; Olanrewaju, HA | 1 |
| Papp, JG; Parratt, JR; Vegh, A | 1 |
| Forghani, R; Krnjević, K | 1 |
| Hashimoto, T; Ishii, R; Kunitomo, M; Shinozuka, K; Takeuchi, K | 1 |
| Hudspeth, DA; McGee, DS; Sato, H; Van Wylen, DG; Vinten-Johansen, J; Williams, MW; Zhao, ZQ | 1 |
| Dawid-Milner, MS; Silva-Carvalho, L; Spyer, KM; St Lambert, JH | 1 |
| Elnazir, BK; Marshall, JM; Thomas, T | 1 |
| Neild, GH; Patel, VC; Woolfson, RG; Yellon, DM | 1 |
| Collis, MG; Hourani, SM; Lewis, CD; Long, CJ | 1 |
| Bullough, DA; Montag, A; Mullane, KM; Young, MA; Zhang, C | 1 |
| Martin, PL; Potts, AA | 1 |
| Downey, JM; Liu, GS; Mullane, K; Olsson, RA; Richards, SC; Walsh, RS | 1 |
| Belardinelli, L; Buchanan, LV; Gibson, JK; Kabell, G | 1 |
| Dawid-Milner, MS; Goldsmith, GR; Silva-Carvalho, L; Spyer, KM | 1 |
| Baxter, GF; Marber, MS; Patel, VC; Yellon, DM | 1 |
| Barrett, R; Belardinelli, L; Rush, W; Sidi, A; Wesley, R | 1 |
| Kokubun, S; Suzuki, H | 1 |
| Haraoka, S; Maekawa, K; Obayashi, N; Saito, D; Uchida, S | 1 |
| Carruthers, AM; Fozard, JR | 1 |
| McGee, DS; Nakanishi, K; Tan, P; Vinten-Johansen, J; Zhao, ZQ | 1 |
| Li, CG; Najbar, A; Rand, MJ | 1 |
| Fozard, JR; Hannon, JP | 1 |
| Burckhartt, B; Cohen, MV; Downey, JM; Mullane, KM; Tsuchida, A; Yang, XM | 1 |
| Abdel-Rahman, AA; el-Mas, MM; Fahim, M; Mustafa, SJ | 1 |
| Gidday, JM; Gonzales, ER; Park, TS; Ruth, VJ | 1 |
| Ahmad, M; Ashraf, M; Suleiman, J | 1 |
| Ervin, MG; Koos, BJ; Mason, BA | 1 |
| Jacobson, KA; Niiya, K; Olsson, RA; Silvia, SK | 1 |
| Cave, AC; Collis, CS; Downey, JM; Hearse, DJ | 1 |
| Lacroix, C; Lynch, AE; McKean, TA; Sterling, H; Streeby, DR; Vestal, RE | 1 |
| Gidday, JM; Park, TS | 1 |
| Burnstock, G; Vials, A | 1 |
| Krnjević, K; Zhu, PJ | 3 |
| Bruns, RF; Montamat, SC; Mudumbi, RV; Vestal, RE | 1 |
| Hirsch, AJ; Liang, BT | 1 |
| Kloner, RA; Li, Y | 1 |
| Lenhard, SD; Martin, SE; Odle, BM; Offenbacher, S; Schmarkey, LS | 1 |
| Chauvelot-Moachon, L; Chen, YL; De Sousa, M; Florentin, I; Giroud, JP; Le Vraux, V; Masson, I | 1 |
| Cohen, MV; Downey, JM; Goto, M; Walsh, RS | 1 |
| Pattison, CW; Pugsley, WB; Walker, DM; Walker, JM; Yellon, DM | 1 |
| Chau, A; Koos, BJ; Ogunyemi, D | 1 |
| Hope, W; Rose'Meyer, RB; White, PJ | 1 |
| Duling, BR; Linden, J; Shepherd, RK | 1 |
| Adeyemo, O; Buchanan, P; Jain, N; Kemp, N; Stone, TW | 1 |
| Albrecht, RF; Koenig, HM; Pelligrino, DA; Wang, Q | 1 |
| DiFrancesco, D; Rocchetti, M; Zaza, A | 1 |
| Hourani, SM; Prentice, DJ | 3 |
| Hettinger-Smith, BD; Leid, M; Murray, TF | 1 |
| Spyer, KM; Thomas, T | 2 |
| Burnstock, G; Höpker, VH; Saffrey, MJ | 1 |
| Marshall, JM; Skinner, MR | 1 |
| Konnaris, K; Lloyd, HG; Temple, DM | 1 |
| Berr, SS; Headrick, JP; Matherne, GP | 1 |
| Cohen, MV; Downey, JM; Goto, M; van Wylen, DG | 1 |
| Abe, T; Gutterman, DD; Morgan, DA | 1 |
| Downey, HF; Gao, ZP; He, MX; Mallet, RT; Sun, J | 1 |
| Funaya, H; Hori, M; Kitakaze, M; Minamino, T; Mori, H; Node, K; Shinozaki, Y | 1 |
| Baxter, GF; Kerac, M; Yellon, DM; Zaman, MJ | 1 |
| Friedman, E; Gao, E; Horwitz, J; Johnson, MD; Roberts, J; Snyder, DL | 1 |
| Byford, AM; Gauthier, NS; Headrick, JP; Linden, J; Matherne, GP | 1 |
| Ji, T; Kessey, K; Mogul, DJ; Overstreet, LS; Trommer, BL | 1 |
| Deguchi, H; Gabazza, EC; Hayashi, N; Suzuki, K; Takeya, H; Urano, H; Wada, H | 1 |
| Hourani, SM; Lewis, CD | 1 |
| Grund, F; Ilebekk, A; Jynge, P; Kirkebøen, KA; Offstad, J; Sommerschild, HT | 1 |
| Hourani, SM; Nicholls, J; Skene, DJ | 1 |
| Hourani, SM; Payne, SL; Prentice, DJ | 1 |
| Asanuma, H; Funaya, H; Hori, M; Kitakaze, M; Kuzuya, T; Minamino, T; Sato, H; Ueda, Y | 1 |
| Friedman, E; Horwitz, J; Pelleg, A; Roberts, J; Snyder, DL; Wang, W | 1 |
| Ebihara, Y; Hasegawa, H; Shinmura, K; Suganuma, Y; Takayama, M; Tamaki, K; Tani, M | 1 |
| Asanuma, H; Funaya, H; Hori, M; Kitakaze, M; Kuzuya, T; Matsuzawa, Y; Minamino, T; Sato, H; Shiraga, M; Tomiyama, Y; Ueda, Y | 1 |
| Coney, AM; Marshall, JM | 2 |
| Burnstock, G; King, BF; Townsend-Nicholson, A; Wildman, SS | 1 |
| Hettinger, BD; Leid, M; Murray, TF | 1 |
| Suarez, J; Torres, JC | 1 |
| Borger, MA; Cohen, G; Li, RK; Merante, F; Mickle, DA; Mohabeer, MK; Rao, V; Shirai, T; Tumiati, LC; Weisel, RD | 2 |
| Assmann, H; Illes, P; Nörenberg, W; Richter, M; Wirkner, K | 1 |
| Florio, C; Frausin, F; Gaion, RM; Vertua, R | 2 |
| Asanuma, H; Hori, M; Kitakaze, M; Koretsune, Y; Kuzuya, T; Minamino, T; Ueda, Y | 1 |
| Crosson, CE; Petrovich, M | 1 |
| Carley, DW; Radulovacki, M | 1 |
| Deindl, E; Ilebekk, A; Jynge, P; Kirkebøen, KA; Lunde, PK; Sommerschild, HT | 1 |
| de Jong, JW; de Jonge, R | 1 |
| Feigl, EO; Gorman, MW; Olsson, RA; Richmond, KN; Tune, JD | 1 |
| Marbán, E; O'Rourke, B; Sasaki, N; Sato, T | 1 |
| Ferguson, JL; Law, WR; Rice, AN; Sam, AD; Sharma, AC | 1 |
| Bradamante, S; de Jong, JW; de Jonge, R; Giacometti, D | 1 |
| Araki, T; Kiyokawa, Y; Power, GG; Sawa, R; Suzuki, S; Yoneyama, Y | 1 |
| Davis, CW; Morse, DM; Smullen, JL | 1 |
| Gitlin, JM; Mitchell, JA; Stanford, SJ | 1 |
| de Zeeuw, S; Duncker, DJ; Liem, DA; van den Doel, MA; Verdouw, PD | 1 |
| Cerniway, RJ; Headrick, JP; Matherne, GP; Peart, J | 1 |
| Cheng, JT; Chi, TC; Liu, IM | 1 |
| Bradley, KK; Bradley, ME | 1 |
| Breschi, MC; Calderone, V; Martinotti, E; Nieri, P | 1 |
| Inoue, H; Kikkawa, K; Mochida, H; Noto, T | 1 |
| Delbro, DS; Giglio, D; Tobin, G | 1 |
| Shimada, H; Sugino, H; Tsuchimoto, K | 1 |
| Bültmann, R; Klebroff, W; Starke, K | 1 |
| Arase, S; Fukui, K; Li, M; Marubayashi, A; Nakaya, Y | 1 |
| Imamura, H; Kido, M; Lu, K; Ninomiya, H; Otani, H; Uchiyama, T | 1 |
| Araki, T; Power, GG; Sawa, R; Suzuki, S; Yoneyama, K; Yoneyama, Y | 1 |
| Duncker, DJ; Kazim, S; Liem, DA; Ploeg, H; Verdouw, PD | 1 |
| Othman, T; Rivkees, SA; Schwartz, M; Turner, CP; Yan, H | 1 |
| Abbas, MR; Coney, AM; Marshall, JM; Ray, CJ | 1 |
| Karasawa, A; Katagiri, C; Kusaka, H; Mizutani, M; Nan-ya, K; Nishikawa, S; Noji, T; Sano, J | 1 |
| Franke, H; Illes, P; Kittner, H; Krügel, U | 1 |
| Barenghi, L; Beemster, P; Bertelli, AA; Bradamante, S; De Jong, JW; De Jonge, R; Piccinini, F | 1 |
| Blood, AB; Hunter, CJ; Power, GG | 1 |
| Bueters, TJ; Joosen, MJ; van Helden, HP | 1 |
| Asakura, M; Asanuma, H; Hori, M; Kitakaze, M; Minamino, T; Mori, H; Node, K; Ogai, A; Ogita, H; Sanada, S; Shinozaki, Y; Takashima, S; Tomoike, H | 1 |
| Ferré, S; Goldberg, SR; Karcz-Kubicha, M; Müller, CE; Schindler, CW; Tella, SR; Thorndike, EB | 1 |
| Burnstock, G; Grishin, SN; Kamaliev, RR; Zefirov, AL; Ziganshin, AU; Ziganshina, LE | 1 |
| Baba, K; Fujiwara, H; Kariya, T; Kawai, T; Minatoguchi, S; Takahashi, M; Takemura, G; Uno, Y; Zhang, C | 1 |
| Farkas, GA; Lee, SD; Nakano, H | 1 |
| Amerson, BS; Guyton, RA; Halkos, ME; Headrick, JP; Kerendi, F; Kin, H; Lofye, MT; Vinten-Johansen, J; Zatta, AJ; Zhao, ZQ | 1 |
| Asanuma, H; Fujita, M; Hirata, A; Hori, M; Kim, J; Kitakaze, M; Minamino, T; Node, K; Ogai, A; Ogita, H; Sanada, S; Tomoike, H; Tsukamoto, O | 1 |
| Boerma, M; Hauer-Jensen, M; Joseph, J; Kennedy, RH; Melchert, RB; Owings, R | 1 |
| Marshall, JM; Walsh, MP | 1 |
| Eppel, GA; Evans, RG; Ventura, S | 1 |
| Driedzic, WR; MacCormack, TJ | 1 |
| Ashton, KJ; Blackburn, MR; Headrick, JP; Matherne, GP; Peart, JN; Reichelt, ME; Willems, L | 1 |
| Coskun, C; Mutlu, D; Savci, V; Suzer, O; Yalcin, M; Yilmaz, MS | 1 |
| Ben Addi, A; Boeynaems, JM; Communi, D; Hua, X; Ledent, C; Lefort, A; Libert, F; Macours, P; Robaye, B; Tilley, SL | 1 |
| Aalkjaer, C; Bek, T; Holmgaard, K; Lambert, JD | 1 |
| Mancardi, D; Pagliaro, P; Penna, C; Tullio, F | 1 |
| Sheppy, E; Wong, T; Wu, C; Wu, X; Zhang, L | 1 |
| Ichinose, TK; O'Leary, DS; Scislo, TJ | 1 |
| Marshall, JM; Ray, CJ | 1 |
| Burnstock, G; Grishin, SN; Kamaliev, RR; Ziganshin, AU; Ziganshin, BA | 1 |
| Davidson, SM; Gonçalves, L; Hausenloy, DJ; Mocanu, MM; Monteiro, P; Paiva, M; Providência, L; Riksen, NP; Rongen, GA; Smits, P; Yellon, DM | 1 |
| Honbo, N; Karliner, JS; Li, L; Vessey, DA | 1 |
| Glaumann, C; Grishina, VA; Gustafsson, LE; Nilsson, KF | 1 |
| Groszmann, RJ; Mehal, WZ; Ripoll, C; Zipprich, A | 1 |
| Boydens, C; Maenhaut, N; Van de Voorde, J | 1 |
| Ishibashi, T; Kaneshiro, T; Machii, H; Maruyama, Y; Saitoh, S; Takeishi, Y; Yamaguchi, O | 1 |
| Ciocan, D; Constantinescu, AO; Ilie, A; Moldovan, M; Zagrean, AM; Zagrean, L | 1 |
| Adair, TH; Cockrell, K; George, EM; Granger, JP | 1 |
| Masereeuw, R; Rongen, GA; van der Hoorn, JW; van der Vliet, JA; Wagener, FA; Warlé, MC; Wever, KE | 1 |
| Aoyama, T; Bai, Y; Iwasa, M; Minatoguchi, S; Murakami, H; Nishigaki, K; Sumi, S; Takemura, G; Uno, B; Ushikoshi, H; Yamada, Y | 1 |
| Berdeaux, A; Chenoune, M; Cohen, MV; Darbera, L; Downey, JM; Ghaleh, B; Lidouren, F; Tissier, R | 1 |
| Grishin, SN; Kamaliev, RR; Teplov, AY; Ziganshin, AU | 1 |
| Ichinose, TK; Li, C; Minic, Z; O'Leary, DS; Scislo, TJ | 1 |
| Gupta, RC; Kohli, S; Lanfear, DE; Rastogi, S; Sabbah, HN; Wang, M; Zhang, K | 1 |
| Caldarone, CA; Callahan, J; Fu, YY; Kato, H; Leung, CH; Nielsen, JM; Redington, AN; Tropak, MB; Wang, L | 1 |
| Ledent, C; Mustafa, SJ; Teng, B; Tilley, S; Zhou, X | 1 |
| Combs, VM; Drew, KL; Jinka, TR | 1 |
| Gabdrakhmanov, AI; Grishin, SN; Khairullin, AE; Ziganshin, AU; Ziganshin, BA; Ziganshina, LE; Zobov, VV | 1 |
1 trial(s) available for 8-(4-sulfophenyl)theophylline and adenosine
| Article | Year |
|---|---|
Relation between adenosine and T-helper 1/T-helper 2 imbalance in women with preeclampsia.
Topics: Adenosine; Adult; CD4-Positive T-Lymphocytes; Female; Humans; In Vitro Techniques; Interferon-gamma; Interleukin-1; Interleukin-2; Interleukin-4; Pre-Eclampsia; Pregnancy; Purinergic P1 Receptor Antagonists; Theophylline | 2002 |
216 other study(ies) available for 8-(4-sulfophenyl)theophylline and adenosine
| Article | Year |
|---|---|
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Peripheral vibration causes an adenosine-mediated postsynaptic inhibitory potential in dorsal horn neurons of the cat spinal cord.
Topics: Adenosine; Adenosine Monophosphate; Animals; Bicuculline; Cats; Evoked Potentials; Iontophoresis; Membrane Potentials; Naloxone; Neurons; Pain; Physical Stimulation; Purinergic Antagonists; Spinal Cord; Strychnine; Synapses; Theophylline; Vibration | 1992 |
Stable adenine nucleotides inhibit [3H]-noradrenaline release in rabbit brain cortex slices by direct action at presynaptic adenosine A1-receptors.
Topics: Adenine Nucleotides; Adenosine; Adenosine Deaminase Inhibitors; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Cerebral Cortex; Drug Interactions; Drug Stability; Electric Stimulation; Female; Male; Nerve Endings; Norepinephrine; Purinergic Antagonists; Rabbits; Receptors, Purinergic; Suramin; Synapses; Theophylline; Tritium; Xanthines | 1992 |
Adenosine-induced hyperpolarization is depressed by glibenclamide in rat CA1 neurones.
Topics: 2-Chloroadenosine; Adenosine; Animals; Glyburide; Hippocampus; In Vitro Techniques; Male; Neurons; Potassium Channels; Rats; Rats, Sprague-Dawley; Receptors, Purinergic; Tetrodotoxin; Theophylline | 1992 |
Interstitial adenosine with dipyridamole: effect of adenosine receptor blockade and adenosine deaminase.
Topics: Adenosine; Adenosine Deaminase; Animals; Coronary Circulation; Dialysis; Dipyridamole; Dogs; Extracellular Space; Female; Hemodynamics; Hypoxanthine; Hypoxanthines; Inosine; Male; Purinergic Antagonists; Theophylline | 1992 |
Myocardial protective effects of adenosine. Infarct size reduction with pretreatment and continued receptor stimulation during ischemia.
Topics: Adenosine; Animals; Coronary Circulation; Coronary Disease; Heart; Hemodynamics; Male; Methods; Myocardial Infarction; Myocardium; Rabbits; Receptors, Purinergic; Theophylline | 1992 |
Penetration of adenosine antagonists into mouse brain as determined by ex vivo binding.
Topics: Adenosine; Animals; Brain Chemistry; Cerebrovascular Circulation; Injections, Intraperitoneal; Locomotion; Male; Mice; Receptors, Purinergic; Theophylline; Time Factors; Xanthines | 1992 |
Role of endothelium-derived relaxing factor in the in vivo renal vascular action of adenosine in dogs.
Topics: Acetylcholine; Adenosine; Animals; Arginine; Dogs; Female; Hemodynamics; Kidney; Male; Nitric Oxide; Nitroarginine; omega-N-Methylarginine; Phenethylamines; Renal Circulation; Theophylline | 1992 |
Adenosine modulation of neuroeffector transmission in guinea-pig uterine smooth muscle.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Electric Stimulation; Female; Guinea Pigs; In Vitro Techniques; Muscle, Smooth; Myometrium; Synaptic Transmission; Theophylline; Uterine Contraction | 1991 |
Extracellular guanosine increases astrocyte cAMP: inhibition by adenosine A2 antagonists.
Topics: Adenosine; Animals; Astrocytes; Brain; Cell Division; Cells, Cultured; Chick Embryo; Cyclic AMP; Guanosine; Purinergic Antagonists; Receptors, Purinergic; Second Messenger Systems; Theophylline; Xanthines | 1991 |
Nucleotide modulation of norepinephrine release from sympathetic nerves in the rat vas deferens.
Topics: Adenosine; Adenosine Triphosphate; Animals; Chromatography, High Pressure Liquid; Male; Neurotransmitter Agents; Norepinephrine; Nucleotides; Rats; Rats, Inbred F344; Receptors, Purinergic; Sympathetic Nervous System; Theophylline; Vas Deferens | 1991 |
Direct effects of adenylyl 5'-(beta,gamma-methylene)diphosphonate, a stable ATP analogue, on relaxant P1-purinoceptors in smooth muscle.
Topics: Adenosine; Adenosine Triphosphate; Animals; Guinea Pigs; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth; Purines; Rats; Rats, Inbred Strains; Receptors, Purinergic; Theophylline | 1991 |
Do adenosinergic substrates mediate methylxanthine effects upon reinforcement thresholds for electrical brain stimulation in the rat?
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Brain; Carbolines; Chlordiazepoxide; Electric Stimulation; Hypothalamic Area, Lateral; Male; Midazolam; Phenylisopropyladenosine; Quinazolines; Rats; Rats, Inbred Strains; Receptors, Purinergic; Reinforcement, Psychology; Self Stimulation; Sensory Thresholds; Theophylline; Triazoles | 1991 |
Adenosine receptor blockade enhances isoproterenol-induced increases in cardiac interstitial adenosine.
Topics: Adenosine; Animals; Extracellular Space; In Vitro Techniques; Isoproterenol; Male; Myocardium; Perfusion; Purinergic Antagonists; Rats; Rats, Inbred Strains; Receptors, Purinergic; Theophylline | 1991 |
Relaxant effects of adenosine analogs on guinea pig trachea in vitro: xanthine-sensitive and xanthine-insensitive mechanisms.
Topics: Adenosine; Animals; Carbachol; Deoxyadenosines; Guinea Pigs; In Vitro Techniques; Male; Muscle Relaxation; Receptors, Purinergic; Theophylline; Thionucleosides; Trachea; Xanthine; Xanthines | 1991 |
Adenosine receptor blockade with 8-p-sulfophenyltheophylline aggravates coronary constriction.
Topics: Adenosine; Animals; Coronary Circulation; Coronary Vessels; Dogs; Drug Synergism; Female; Hemodynamics; Male; Neuropeptide Y; Receptors, Purinergic; Regional Blood Flow; Theophylline; Vascular Resistance; Vasoconstriction | 1991 |
Protection against infarction afforded by preconditioning is mediated by A1 adenosine receptors in rabbit heart.
Topics: Adenosine; Animals; Female; Hemodynamics; Male; Myocardial Infarction; Myocardial Reperfusion; Purines; Rabbits; Receptors, Purinergic; Sulfonamides; Theophylline | 1991 |
Adenosine receptor antagonism attenuates angiotensin II effects on adrenergic neurotransmission in the rabbit isolated vas deferens.
Topics: Adenosine; Adenosine Triphosphate; Angiotensin II; Animals; Electric Stimulation; In Vitro Techniques; Male; Muscle Contraction; Norepinephrine; Purinergic Antagonists; Rabbits; Receptors, Adrenergic; Receptors, Purinergic; Synaptic Transmission; Theophylline; Vas Deferens | 1990 |
Fc gamma receptor-mediated functions in neutrophils are modulated by adenosine receptor occupancy. A1 receptors are stimulatory and A2 receptors are inhibitory.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Antigens, Differentiation; Cell Adhesion; Cells, Cultured; Dose-Response Relationship, Drug; Flow Cytometry; Humans; In Vitro Techniques; Neutrophils; Pertussis Toxin; Phagocytosis; Phenylisopropyladenosine; Receptors, Fc; Receptors, IgG; Receptors, Purinergic; Superoxides; Theophylline; Virulence Factors, Bordetella | 1990 |
Cerebral ischemia in gerbils: postischemic administration of cyclohexyl adenosine and 8-sulfophenyl-theophylline.
Topics: Adenosine; Animals; Blood Pressure; Brain Ischemia; Drug Interactions; Female; Gerbillinae; Theophylline | 1990 |
Central adenosinergic system involvement in ethanol-induced motor incoordination in mice.
Topics: Adenosine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Ataxia; Brain; Dose-Response Relationship, Drug; Drug Synergism; Ethanol; Injections, Intraperitoneal; Injections, Intravenous; Male; Mice; Mice, Inbred Strains; Motor Activity; Phenylisopropyladenosine; Psychomotor Performance; Receptors, Purinergic; Theophylline; Time Factors; Tissue Distribution; Tritium; Xanthines | 1990 |
Adenosine involvement in postictal events in amygdala-kindled rats.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Amygdala; Animals; Anticonvulsants; Caffeine; Electric Stimulation; Electrodes, Implanted; Electroencephalography; Kindling, Neurologic; Male; Rats; Seizures; Theophylline; Time Factors | 1990 |
The selective adenosine A2 receptor agonist, CGS 21680, is a potent depressant of cerebral cortical neuronal activity.
Topics: Adenosine; Animals; Cerebral Cortex; Evoked Potentials; Male; Neural Inhibition; Phenethylamines; Rats; Rats, Inbred Strains; Receptors, Purinergic; Theophylline | 1990 |
Adenosine antagonists alter the synaptic response to in vitro ischemia in the rat hippocampus.
Topics: Action Potentials; Adenosine; Animals; Cell Hypoxia; Electric Stimulation; Hippocampus; In Vitro Techniques; Male; Neural Inhibition; Rats; Rats, Inbred Strains; Theophylline | 1990 |
Adenosine modulation of resting vascular tone in rabbit skeletal muscle.
Topics: Adenosine; Animals; Arteries; Arterioles; Dose-Response Relationship, Drug; Microcirculation; Muscles; Rabbits; Theophylline; Vasoconstriction; Vasomotor System; Xanthines | 1990 |
Action of N6(amido-3-propyl) adenosine hydrochloride (Agr 529) on plasma corticosterone levels in rats.
Topics: Adenosine; Animals; Corticosterone; Male; Pituitary Gland; Rats; Rats, Inbred Strains; Receptors, Purinergic; Theophylline | 1990 |
Anticonvulsant effect of N-ethylcarboxamidoadenosine against kainic acid-induced behavioral seizures in the rat prepiriform cortex.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Dilazep; Kainic Acid; Limbic System; Male; Rats; Rats, Inbred Strains; Seizures; Theophylline | 1990 |
Co-purification of A1 adenosine receptors and guanine nucleotide-binding proteins from bovine brain.
Topics: Adenosine; Affinity Labels; Animals; Brain Chemistry; Cattle; Chromatography, Affinity; Electrophoresis, Polyacrylamide Gel; Ethylmaleimide; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Molecular Weight; Receptors, Purinergic; Theophylline; Thionucleotides; Xanthines | 1989 |
Adenosine enhancement of adrenergic neuroeffector transmission in guinea-pig pulmonary artery.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Electric Stimulation; Female; Guinea Pigs; In Vitro Techniques; Male; Norepinephrine; Pulmonary Artery; Receptors, Purinergic; Sympathetic Nervous System; Synaptic Transmission; Theophylline; Vasoconstriction; Vasodilator Agents | 1989 |
Presynaptic modulation of sympathetic nerve transmission--an element in vasomotor control.
Topics: Adenosine; Adrenergic alpha-Antagonists; Animals; Hydroxydopamines; Muscles; Oxidopamine; Phentolamine; Phenylisopropyladenosine; Rana temporaria; Receptors, Purinergic; Sympathetic Nervous System; Synaptic Transmission; Tetrodotoxin; Theophylline; Vasomotor System; Video Recording; Xanthines | 1989 |
Role of adenosine in hypoxic alterations of anaphylaxis of isolated guinea pig hearts.
Topics: Adenosine; Anaphylaxis; Animals; Antigens; Atrioventricular Node; Coronary Circulation; Guinea Pigs; Heart; Hemodynamics; Histamine; Hypoxia; In Vitro Techniques; Inosine; Male; Myocardium; Theophylline; Thromboxanes | 1989 |
NECA-induced hypomotility in mice: evidence for a predominantly central site of action.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Central Nervous System; Male; Mice; Motor Activity; Receptors, Purinergic; Theophylline | 1989 |
The effect of local infusion of adenosine and adenosine analogues on local cerebral blood flow.
Topics: 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Cerebrovascular Circulation; Dialysis; Injections, Intraventricular; Perfusion; Rats; Rats, Inbred Strains; Theophylline | 1989 |
On the nature of endogenous purines modulating cholinergic neurotransmission in the guinea-pig ileum.
Topics: Adenine Nucleotides; Adenosine; Adenosine Deaminase; AMP Deaminase; Animals; Cholinergic Fibers; Electric Stimulation; Gastrointestinal Motility; Guinea Pigs; Ileum; Male; Muscle Contraction; Muscle, Smooth; Purines; Synaptic Transmission; Theophylline | 1987 |
Adenosine promotes neutrophil chemotaxis.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Chemotaxis, Leukocyte; Drug Synergism; Humans; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Receptors, Purinergic; Stimulation, Chemical; Superoxides; Theophylline; Zymosan | 1988 |
L-phenylisopropyladenosine (L-PIA) diminishes halothane anesthetic requirements and decreases noradrenergic neurotransmission in rats.
Topics: Adenosine; Anesthesia; Animals; Brain; Halothane; Male; Norepinephrine; Phenylisopropyladenosine; Rats; Rats, Inbred Strains; Synaptic Transmission; Theophylline | 1988 |
Central effects of adenosine analogs on stress-induced gastric ulcer formation.
Topics: Adenosine; Animals; Anti-Anxiety Agents; Injections, Intraventricular; Male; Phenylisopropyladenosine; Rats; Rats, Inbred Strains; Receptors, Purinergic; Stomach Ulcer; Stress, Physiological; Theophylline | 1987 |
Dual effects of adenosine and adenosine analogues on motor activity of the human fallopian tube.
Topics: 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adult; Fallopian Tubes; Female; Humans; Lidocaine; Menstruation; Middle Aged; Muscle Contraction; Muscle, Smooth; Phenylisopropyladenosine; Receptors, Cell Surface; Receptors, Purinergic; Tetrodotoxin; Theophylline | 1985 |
Cerebral blood flow and interstitial fluid adenosine during hemorrhagic hypotension.
Topics: Adenosine; Animals; Blood Pressure; Brain; Carbon Dioxide; Cerebrovascular Circulation; Dialysis; Extracellular Space; Hemorrhage; Homeostasis; Hypotension; Male; Rats; Rats, Inbred Strains; Receptors, Purinergic; Theophylline; Vascular Resistance | 1988 |
Inhibition of rat ventricular automaticity by adenosine.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adenylyl Cyclases; Animals; Atropine; Depression, Chemical; Electric Stimulation; Electrocardiography; Heart Rate; Heart Ventricles; Male; Propranolol; Rats; Rats, Inbred Strains; Stereoisomerism; Systole; Theophylline | 1985 |
Characterization of prejunctional purinoceptors on adrenergic nerves of the rat caudal artery.
Topics: 2-Chloroadenosine; Adenosine; Adenosine Triphosphate; Animals; Arteries; Azides; Electric Stimulation; Male; Norepinephrine; Rats; Rats, Inbred F344; Receptors, Purinergic; Sympathetic Nervous System; Theophylline | 1988 |
Adenosine as a modulator of sympathetic nerve-stimulation-induced release of noradrenaline from the isolated rabbit heart.
Topics: Adenosine; Animals; Electric Stimulation; Female; Heart; Male; Myocardial Contraction; Norepinephrine; Rabbits; Receptors, Purinergic; Sympathetic Nervous System; Theophylline | 1988 |
Evidence that adenosine mediates the depression of spinal dorsal horn neurons induced by peripheral vibration in the cat.
Topics: Adenosine; Animals; Bicuculline; Blood Pressure; Caffeine; Cats; Dipyridamole; Injections, Intravenous; Iontophoresis; Naloxone; Neurons; Spinal Cord; Strychnine; Theophylline; Vibration | 1987 |
Antagonism of the cardiovascular effects of adenosine by caffeine or 8-(p-sulfophenyl)theophylline.
Topics: Adenosine; Blood Pressure; Brain; Caffeine; Heart Rate; Hemodynamics; Receptors, Purinergic; Theophylline | 1987 |
An in vitro analysis of purine-mediated renal vasoconstriction in rat isolated kidney.
Topics: 2-Chloroadenosine; Adenosine; Animals; Colforsin; Male; Methoxamine; Phenylisopropyladenosine; Rats; Rats, Inbred Strains; Receptors, Purinergic; Renal Circulation; Theophylline; Vasoconstriction; Xanthines | 1987 |
Potent depressant effects of adenosine analogs on hippocampal slow-wave activity in the unanesthetized rat.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Depression, Chemical; Electroencephalography; Hippocampus; Male; Phenylisopropyladenosine; Rats; Rats, Inbred Strains; Stereoisomerism; Theophylline | 1985 |
Adenosine antagonism and related effects of theophylline derivatives in guinea pig ileum longitudinal muscle.
Topics: 2-Chloroadenosine; Acetylcholine; Adenosine; Animals; Atropine; Choline; Electric Stimulation; Guinea Pigs; Ileum; Male; Muscle Contraction; Muscle, Smooth; Pyrrolidinones; Rolipram; Synaptic Transmission; Tetrodotoxin; Theophylline | 1984 |
Relaxation of rings of canine cerebral artery produced by adenosine and its analogues.
Topics: Adenosine; Animals; Apamin; Cerebral Arteries; Dogs; Female; In Vitro Techniques; Indomethacin; Male; Muscle, Smooth, Vascular; Serotonin; Theophylline; Vasodilation | 1984 |
Potentiation of arginine-induced glucagon secretion by adenosine.
Topics: 2-Chloroadenosine; Adenosine; Animals; Arginine; Drug Synergism; Glucagon; Insulin; Insulin Secretion; Male; Pancreas; Phenylisopropyladenosine; Rats; Theophylline | 1981 |
Preconditioning of isolated rabbit cardiomyocytes: induction by metabolic stress and blockade by the adenosine antagonist SPT and calphostin C, a protein kinase C inhibitor.
Topics: Adenosine; Animals; Cell Size; Cell Survival; Cells, Cultured; Glucose; Heart; Myocardial Ischemia; Myocardium; Naphthalenes; Polycyclic Compounds; Protein Kinase C; Rabbits; Theophylline; Time Factors | 1994 |
Differential effects of ATP- and 2-methylthioATP-induced relaxation in guinea pig coronary vasculature.
Topics: Adenosine; Adenosine Triphosphate; Animals; Arginine; Coronary Vessels; Electrophysiology; Female; Guinea Pigs; In Vitro Techniques; Indomethacin; Male; Muscle Relaxation; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Purinergic Antagonists; Theophylline; Thionucleotides | 1994 |
Adenosine receptor specificity in preconditioning of isolated rabbit cardiomyocytes: evidence of A3 receptor involvement.
Topics: Adenosine; Animals; Antihypertensive Agents; Cells, Cultured; Glucose; Myocardial Infarction; Myocardial Ischemia; Myocardium; Naphthalenes; Phenethylamines; Phenylisopropyladenosine; Polycyclic Compounds; Protein Kinase C; Purinergic Antagonists; Pyruvates; Pyruvic Acid; Rabbits; Receptors, Purinergic P1; Theophylline; Time Factors; Trypan Blue; Xanthines | 1994 |
Contribution of P1-(A2b subtype) and P2-purinoceptors to the control of vascular tone in the rat isolated mesenteric arterial bed.
Topics: 2-Chloroadenosine; Adenosine; Adenosine Triphosphate; Adenosine-5'-(N-ethylcarboxamide); Animals; Antihypertensive Agents; Arginine; Dose-Response Relationship, Drug; Enzyme Inhibitors; In Vitro Techniques; Male; Mesenteric Arteries; Methoxamine; NG-Nitroarginine Methyl Ester; Phenethylamines; Rats; Rats, Wistar; Receptors, Purinergic P1; Receptors, Purinergic P2; Theophylline; Thionucleotides; Vasoconstriction; Vasoconstrictor Agents; Vasodilator Agents | 1995 |
The purinoceptors of the guinea-pig isolated taenia caeci.
Topics: Adenosine; Animals; Cecum; Female; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Receptors, Purinergic; Suramin; Theophylline | 1995 |
Post-ischemic hyperemia in the cat retina: the effects of adenosine receptor blockade.
Topics: Adenosine; Animals; Blood Flow Velocity; Cats; Choroid; Hemodynamics; Hyperemia; Ischemia; Microspheres; Purinergic P1 Receptor Antagonists; Regional Blood Flow; Reperfusion; Retinal Vessels; Theophylline | 1995 |
Endogenous adenosine modulates alpha 2- but not alpha 1-adrenergic constriction of coronary arterioles.
Topics: Adenosine; Adrenergic alpha-Agonists; Animals; Arterioles; Azepines; Blood Pressure; Coronary Circulation; Coronary Vessels; Dogs; Female; Heart Rate; Male; Microscopy, Fluorescence; Muscle, Smooth, Vascular; Phenylephrine; Purinergic P1 Receptor Antagonists; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, alpha-2; Reference Values; Theophylline; Vasoconstriction | 1995 |
Adenosine modulates hypoxia-induced atrial natriuretic peptide release in fetal sheep.
Topics: Adenosine; Animals; Atrial Natriuretic Factor; Blood Pressure; Fetal Blood; Gases; Heart Rate; Hemoglobins; Hydrogen-Ion Concentration; Hypoxia; Purinergic P1 Receptor Antagonists; Sheep; Theophylline | 1995 |
Does interstitial adenosine mediate acute hibernation of guinea pig myocardium?
Topics: 5'-Nucleotidase; Acute Disease; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Cytosol; Guinea Pigs; Heart; Inosine; Lactates; Lactic Acid; Myocardial Ischemia; Myocardial Reperfusion; Myocardial Stunning; Myocardium; Phosphorylation; Theophylline | 1995 |
Role of endothelium in hyperpolarization of coronary smooth muscle by adenosine and its analogues.
Topics: 2-Chloroadenosine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Arginine; Coronary Vessels; Dose-Response Relationship, Drug; Endothelium, Vascular; Humans; In Vitro Techniques; Indomethacin; Membrane Potentials; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; omega-N-Methylarginine; Swine; Theophylline; Vasodilator Agents | 1995 |
Pronounced antiarrhythmic effects of preconditioning in anaesthetized dogs: is adenosine involved?
Topics: Adenosine; Anesthesia, General; Animals; Arrhythmias, Cardiac; Blood Flow Velocity; Blood Pressure; Coronary Circulation; Coronary Vessels; Dogs; Female; Heart; Heart Rate; Hemodynamics; Male; Myocardial Ischemia; Myocardial Reperfusion; Purinergic P1 Receptor Antagonists; Theophylline; Time Factors; Vascular Resistance | 1995 |
Adenosine antagonists have differential effects on induction of long-term potentiation in hippocampal slices.
Topics: Adenosine; Animals; Electric Stimulation; Evoked Potentials; Hippocampus; In Vitro Techniques; Long-Term Potentiation; Male; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Theophylline; Xanthines | 1995 |
Characterization of the facilitatory prejunctional purinoceptor on adrenergic nerves of the rabbit ear artery.
Topics: 2-Chloroadenosine; Adenosine; Adenosine Triphosphate; Adrenergic Fibers; Animals; Arteries; Ear; Female; In Vitro Techniques; Male; Norepinephrine; Purinergic Agonists; Purinergic Antagonists; Rabbits; Receptors, Purinergic; Theophylline | 1995 |
Acadesine reduces myocardial infarct size by an adenosine mediated mechanism.
Topics: Adenosine; Aminoimidazole Carboxamide; Animals; Coronary Circulation; Extracellular Space; In Vitro Techniques; Male; Myocardial Infarction; Myocardial Reperfusion; Myocardium; Rabbits; Receptors, Purinergic P1; Regional Blood Flow; Ribonucleosides; Theophylline | 1995 |
Action of adenosine receptor antagonists on the cardiovascular response to defence area stimulation in the rat.
Topics: Adenosine; Animals; Behavior, Animal; Blood Pressure; Ethanol; Heart Rate; Hemodynamics; Hypothalamus; In Vitro Techniques; Male; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Theophylline; Xanthines | 1994 |
Differentiation of the peripherally mediated from the centrally mediated influences of adenosine in the rat during systemic hypoxia.
Topics: 2-Chloroadenosine; Adenosine; Adenosine Deaminase; Animals; Blood Gas Analysis; Blood Pressure; Heart Rate; Hemodynamics; Hypoxia; Muscle, Skeletal; Purinergic P1 Receptor Antagonists; Rats; Respiration; Theophylline; Vascular Resistance; Vasodilation | 1994 |
Inhibition of nitric oxide synthesis reduces infarct size by an adenosine-dependent mechanism.
Topics: Adenosine; Animals; Arginine; Lactates; Lactic Acid; Male; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide; Perfusion; Rabbits; Theophylline; Time Factors | 1995 |
Characterization of adenosine receptors in the rat isolated aorta.
Topics: Adenosine; Animals; Aorta, Thoracic; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Rats; Rats, Wistar; Receptors, Purinergic P1; Theophylline | 1994 |
Adenosine-mediated inhibition of platelet aggregation by acadesine. A novel antithrombotic mechanism in vitro and in vivo.
Topics: Adenosine; Adenosine Deaminase; Adenosine Kinase; Aminoimidazole Carboxamide; Animals; Aspirin; Blood Physiological Phenomena; Coronary Thrombosis; Coronary Vessels; Dipyridamole; Disease Models, Animal; Dogs; Erythrocytes; Humans; Male; Plasma; Platelet Aggregation; Purinergic P1 Receptor Antagonists; Regional Blood Flow; Ribonucleosides; Theophylline; Tubercidin | 1994 |
The endothelium of the rat renal artery plays an obligatory role in A2 adenosine receptor-mediated relaxation induced by 5'-N-ethylcarboxamidoadenosine and N6-cyclopentyladenosine.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Arginine; Endothelium, Vascular; Glyburide; In Vitro Techniques; Indomethacin; Isoproterenol; Male; Muscle Relaxation; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroprusside; Purinergic P1 Receptor Agonists; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Renal Artery; Renal Circulation; Theophylline; Vasodilator Agents; Xanthines | 1994 |
Evidence that the adenosine A3 receptor may mediate the protection afforded by preconditioning in the isolated rabbit heart.
Topics: Adenosine; Animals; Antihypertensive Agents; Female; In Vitro Techniques; Male; Myocardial Infarction; Myocardial Ischemia; Perfusion; Purinergic Antagonists; Rabbits; Receptors, Purinergic P1; Theophylline; Xanthines | 1994 |
Effects of adenosine on atrial refractoriness and arrhythmias.
Topics: Action Potentials; Adenosine; Animals; Atrial Fibrillation; Dipyridamole; Dogs; Dose-Response Relationship, Drug; Electric Stimulation; Heart Atria; Myocardium; Theophylline | 1994 |
A potential role of central A1 adenosine receptors in the responses to hypothalamic stimulation in the anaesthetized cat.
Topics: Adenosine; Anesthesia; Animals; Blood Pressure; Cats; Chemoreceptor Cells; Electric Stimulation; Ethanol; Hypothalamus; Phrenic Nerve; Pressoreceptors; Receptors, Purinergic P1; Theophylline; Xanthines | 1994 |
Adenosine receptor involvement in a delayed phase of myocardial protection 24 hours after ischemic preconditioning.
Topics: Adenosine; Animals; Heart; Hemodynamics; Male; Myocardial Infarction; Myocardial Ischemia; Myocardial Reperfusion; Rabbits; Receptors, Purinergic P1; Theophylline; Time Factors | 1994 |
Cardiovascular effects of a non-xanthine-selective antagonist of the A1 adenosine receptor in the anaesthetised pig: pharmacological and therapeutic implications.
Topics: Adenine; Adenosine; Anesthesia; Animals; Atropine; Cardiovascular System; Coronary Vessels; Female; Heart; Male; Norbornanes; Propranolol; Purinergic P1 Receptor Antagonists; Regional Blood Flow; Swine; Theophylline | 1994 |
Subtypes of purinoceptors in rat and dog urinary bladder smooth muscles.
Topics: Acetylcholine; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Dogs; Female; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Protein Synthesis Inhibitors; Rats; Rats, Wistar; Receptors, Purinergic P1; Receptors, Purinergic P2; Theophylline; Thionucleotides; Triazines; Urinary Bladder | 1994 |
Role of endothelium-derived nitric oxide and adenosine in functional myocardial hyperemia.
Topics: Adenosine; Animals; Arginine; Coronary Circulation; Dogs; Female; Hemodynamics; Hyperemia; Male; Nitric Oxide; Nitroarginine; Theophylline; Vascular Resistance | 1994 |
The cardiovascular effects of selective adenosine A1 and A2 receptor agonists in the pithed rat: no role for glibenclamide-sensitive potassium channels.
Topics: Adenosine; Adrenergic alpha-Agonists; Angiotensin II; Animals; Benzopyrans; Blood Pressure; Cardiovascular System; Cyclopentanes; Glyburide; Heart Rate; Male; Parasympatholytics; Phenethylamines; Potassium Channels; Rats; Rats, Sprague-Dawley; Receptors, Purinergic; Sensitivity and Specificity; Theophylline; Time Factors | 1993 |
A1 receptor mediated myocardial infarct size reduction by endogenous adenosine is exerted primarily during ischaemia.
Topics: Adenosine; Adrenergic alpha-1 Receptor Antagonists; Animals; Myocardial Infarction; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Phenylisopropyladenosine; Rabbits; Random Allocation; Receptors, Adrenergic, alpha-1; Theophylline; Xanthines | 1994 |
The effect of suramin on vasodilator responses to ATP and 2-methylthio-ATP in the Sprague-Dawley rat coronary vasculature.
Topics: Adenosine; Adenosine Triphosphate; Animals; Coronary Vessels; Drug Interactions; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Perfusion; Rats; Rats, Sprague-Dawley; Suramin; Theophylline; Thionucleotides; Vasodilation; Vasodilator Agents | 1994 |
Pharmacological actions of the coenzymes NAD(H) and NADP(H) on the rat anococcygeus muscle.
Topics: Adenosine; Animals; Arginine; Electric Stimulation; Male; Muscle Contraction; Muscle Relaxation; NAD; NADP; NG-Nitroarginine Methyl Ester; Nitric Oxide; Norepinephrine; Oxidation-Reduction; Rats; Rats, Sprague-Dawley; Theophylline | 1994 |
BW-A522 blocks adenosine A3 receptor-mediated hypotensive responses in the rat.
Topics: Adenosine; Animals; Blood Pressure; Depression, Chemical; Dose-Response Relationship, Drug; Male; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Theophylline; Xanthines | 1994 |
Acadesine extends the window of protection afforded by ischaemic preconditioning.
Topics: Adenosine; Aminoimidazole Carboxamide; Animals; Female; Male; Myocardial Infarction; Myocardial Ischemia; Myocardial Reperfusion; Myocardium; Rabbits; Ribonucleosides; Theophylline; Time Factors | 1994 |
Influence of aortic baroreceptor denervation on adenosine receptor-mediated relaxation of isolated rat aorta.
Topics: Acetylcholine; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Aorta, Thoracic; Arginine; Blood Pressure; Endothelium, Vascular; Heart Rate; In Vitro Techniques; Male; Muscle Denervation; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; omega-N-Methylarginine; Phenylephrine; Pressoreceptors; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Theophylline | 1994 |
Adenosine and cerebrovascular hyperemia during insulin-induced hypoglycemia in newborn piglet.
Topics: Adenosine; Animals; Animals, Newborn; Arterioles; Blood Glucose; Blood Pressure; Brain; Carbon Dioxide; Cerebrovascular Circulation; Hyperemia; Hypoglycemia; Insulin; Muscle, Smooth, Vascular; Oxygen; Partial Pressure; Pia Mater; Regional Blood Flow; Swine; Theophylline; Vasodilation | 1993 |
Adenosine and A1 selective agonists offer minimal protection against ischaemic injury to isolated rat cardiomyocytes.
Topics: Adenosine; Animals; Carbachol; Cell Death; Cells, Cultured; Iodoacetates; Iodoacetic Acid; Isoproterenol; Male; Myocardial Ischemia; Myocardium; Rats; Rats, Sprague-Dawley; Theophylline | 1993 |
Ca2+ preconditioning elicits a unique protection against the Ca2+ paradox injury in rat heart. Role of adenosine. Fixed.
Topics: Adenosine; Animals; Calcium; Male; Microscopy, Electron; Myocardial Reperfusion Injury; Myocardial Stunning; Myocardium; Pertussis Toxin; Phenylisopropyladenosine; Rats; Rats, Sprague-Dawley; Theophylline; Virulence Factors, Bordetella | 1994 |
Adenosine mediates hypoxic release of arginine vasopressin in fetal sheep.
Topics: Adenosine; Animals; Arginine Vasopressin; Blood Pressure; Fetus; Gases; Heart Rate; Hydrogen-Ion Concentration; Hypoxia; Papaverine; Purinergic P1 Receptor Antagonists; Sheep; Theophylline | 1994 |
Covalent binding of a selective agonist irreversibly activates guinea pig coronary artery A2 adenosine receptors.
Topics: Adenosine; Animals; Blood Flow Velocity; Coronary Vessels; Guinea Pigs; Isothiocyanates; Phenethylamines; Receptors, Purinergic; Theophylline; Thiocyanates; Vasodilation | 1993 |
Improved functional recovery by ischaemic preconditioning is not mediated by adenosine in the globally ischaemic isolated rat heart.
Topics: Adenosine; Animals; Coronary Circulation; Disease Models, Animal; Male; Myocardial Contraction; Myocardial Ischemia; Myocardial Reperfusion; Myocardial Reperfusion Injury; Rats; Rats, Wistar; Regional Blood Flow; Theophylline | 1993 |
Effect of adenosine on heart rate in isolated muskrat and guinea pig hearts.
Topics: Adenosine; Adenosine Deaminase; Animals; Arvicolinae; Guinea Pigs; Heart Rate; In Vitro Techniques; Reference Values; Theophylline; Thioinosine; Xanthines | 1993 |
Adenosine-mediated autoregulation of retinal arteriolar tone in the piglet.
Topics: Adenosine; Animals; Arterioles; Homeostasis; Microcirculation; Muscle, Smooth, Vascular; Ocular Hypotension; Oxygen Consumption; Receptors, Purinergic; Retinal Artery; Swine; Theophylline; Thioinosine; Vasodilation; Video Recording | 1993 |
A2-purinoceptor-mediated relaxation in the guinea-pig coronary vasculature: a role for nitric oxide.
Topics: Adenosine; Animals; Antihypertensive Agents; Arginine; Coronary Vessels; Female; Guinea Pigs; In Vitro Techniques; Indomethacin; Male; Muscle Relaxation; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Phenethylamines; Prostaglandins; Receptors, Purinergic; Theophylline; Vasodilation; Xanthines | 1993 |
Adenosine release is a major cause of failure of synaptic transmission during hypoglycaemia in rat hippocampal slices.
Topics: Action Potentials; Adenosine; Animals; Caffeine; Cell Hypoxia; Energy Metabolism; Evoked Potentials; Glucose; Glyburide; Hippocampus; Hypoglycemia; Neural Inhibition; Potassium; Potassium Channels; Rats; Rats, Sprague-Dawley; Synaptic Transmission; Theophylline; Tolbutamide | 1993 |
Manipulation of endogenous adenosine in the rat prepiriform cortex modulates seizure susceptibility.
Topics: Adenosine; Adenosine Deaminase Inhibitors; Adenosine Diphosphate; Adenosine Kinase; Animals; Bicuculline; Cerebral Cortex; Male; Pentostatin; Rats; Rats, Sprague-Dawley; Receptors, Purinergic; Seizures; Theophylline; Thioinosine | 1993 |
Cardiac functional responses to adenosine by PD 81,723, an allosteric enhancer of the adenosine A1 receptor.
Topics: Adenosine; Allosteric Regulation; Animals; Atrial Function; Depression, Chemical; Drug Synergism; Heart; Heart Atria; Heart Rate; Male; Myocardial Contraction; Rats; Rats, Sprague-Dawley; Receptors, Purinergic; Theophylline; Thiophenes; Xanthines | 1993 |
Homologous sensitisation of embryonic chick atrial myocytes to adenosine: mediation by adenosine A1 receptor and guanine nucleotide binding protein.
Topics: Adenosine; Adenosine Deaminase; Adenylyl Cyclases; Animals; Cells, Cultured; Chick Embryo; GTP-Binding Proteins; Isoproterenol; Myocardial Contraction; Myocardium; Phenylisopropyladenosine; Receptors, Purinergic; Theophylline; Up-Regulation | 1993 |
The cardioprotective effects of ischemic 'preconditioning' are not mediated by adenosine receptors in rat hearts.
Topics: Adenosine; Animals; Arrhythmias, Cardiac; Female; Heart; Hemodynamics; Myocardial Ischemia; Myocardial Reperfusion; Myocardium; Necrosis; Purinergic Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Purinergic; Risk Factors; Theophylline | 1993 |
Adenosine regulates coronary blood flow during increased work and decreased supply.
Topics: Adenosine; Animals; Coronary Circulation; Dobutamine; Dogs; Female; Heart; Hemodynamics; Male; Myocardium; Physical Exertion; Theophylline | 1993 |
Inhibition of human monocyte TNF production by adenosine receptor agonists.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Biological Assay; Cells, Cultured; Dexamethasone; Dipyridamole; Endotoxins; Humans; L Cells; Lipopolysaccharides; Male; Mice; Monocytes; Phenylisopropyladenosine; Rats; Rats, Inbred F344; Receptors, Purinergic; Theophylline; Tumor Necrosis Factor-alpha | 1993 |
Hypoxia preconditions rabbit myocardium via adenosine and catecholamine release.
Topics: Adenosine; Adrenergic alpha-Antagonists; Animals; Catecholamines; Heart; Hemodynamics; Hypoxia; In Vitro Techniques; Myocardial Infarction; Myocardial Ischemia; Myocardial Reperfusion; Myocardium; Phenoxybenzamine; Rabbits; Theophylline; Time Factors | 1995 |
Preconditioning in isolated superfused human muscle.
Topics: Adenosine; Animals; Atrial Function; Female; Heart; Humans; In Vitro Techniques; Male; Myocardial Contraction; Myocardial Reperfusion Injury; Perfusion; Rabbits; Receptors, Purinergic P1; Theophylline | 1995 |
Adenosine mediates metabolic and cardiovascular responses to hypoxia in fetal sheep.
Topics: Acidosis; Adenosine; Animals; Blood Pressure; Female; Fetus; Glycolysis; Heart Rate; Hypoxia; Pregnancy; Purinergic P1 Receptor Antagonists; Sheep; Theophylline; Tromethamine | 1995 |
The role of adenosine in the hypotensive actions of morphine.
Topics: Adenosine; Animals; Blood Pressure; Female; Guanethidine; Morphine; Narcotics; Rats; Rats, Wistar; Receptors, Purinergic P1; Theobromine; Theophylline; Xanthines | 1995 |
Adenosine-induced vasoconstriction in vivo. Role of the mast cell and A3 adenosine receptor.
Topics: Adenosine; Animals; Arterioles; Cricetinae; Iodine Radioisotopes; Iodobenzenes; Male; Mast Cells; Mesocricetus; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Theophylline; Vasoconstriction; Vasomotor System; Xanthines | 1996 |
Anxiolytic activity of adenosine receptor activation in mice.
Topics: Adenosine; Analysis of Variance; Animals; Anti-Anxiety Agents; Anxiety; Caffeine; Male; Maze Learning; Mice; Motor Activity; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Theophylline | 1995 |
Role of nitric oxide, adenosine, N-methyl-D-aspartate receptors, and neuronal activation in hypoxia-induced pial arteriolar dilation in rats.
Topics: Adenosine; Animals; Arginine; Arterioles; Dizocilpine Maleate; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Hypoxia, Brain; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Pia Mater; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Tetrodotoxin; Theophylline; Vasodilation | 1995 |
Modulation of the hyperpolarization-activated current (I(f)) by adenosine in rabbit sinoatrial myocytes.
Topics: Acetylcholine; Action Potentials; Adenosine; Analysis of Variance; Animals; Barium Compounds; Cells, Cultured; Chlorides; Egtazic Acid; Heart Conduction System; Manganese Compounds; Membrane Potentials; Models, Cardiovascular; Patch-Clamp Techniques; Purinergic P1 Receptor Antagonists; Rabbits; Receptors, Purinergic P1; Sinoatrial Node; Theophylline | 1996 |
Activation of multiple sites by adenosine analogues in the rat isolated aorta.
Topics: Adenosine; Animals; Aorta, Thoracic; Endothelium, Vascular; Enzyme Inhibitors; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Purines; Rats; Rats, Wistar; Receptors, Purinergic P1; Sulfonamides; Theophylline; Triazines; Triazoles; Xanthines | 1996 |
Chronic exposure to adenosine receptor agonists and antagonists reciprocally regulates the A1 adenosine receptor-adenylyl cyclase system in cerebellar granule cells.
Topics: 2-Chloroadenosine; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adenosine; Adenylyl Cyclases; Animals; Binding, Competitive; Cell Membrane; Cerebellum; GTP-Binding Proteins; Guanylyl Imidodiphosphate; Kinetics; Neurons; Phenylisopropyladenosine; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Theophylline; Time Factors; Xanthines | 1996 |
The role of adenosine receptors in the rostral ventrolateral medulla in the cardiovascular response to defence area stimulation in the rat.
Topics: Adenosine; Animals; Blood Pressure; Cardiovascular Physiological Phenomena; Cardiovascular System; Defense Mechanisms; Electric Stimulation; Heart Rate; Hypothalamus; Male; Medulla Oblongata; Microinjections; Muscle, Skeletal; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Regional Blood Flow; Theophylline | 1996 |
Neurite outgrowth of striatal neurons in vitro: involvement of purines in the growth-promoting effect of myenteric plexus explants.
Topics: 2-Chloroadenosine; Adenosine; Adenosine Triphosphate; Aminohydrolases; Animals; Cells, Cultured; Colforsin; Drug Interactions; Fibroblast Growth Factors; Fibronectins; Gangliosides; Guanosine Triphosphate; Laminin; Myenteric Plexus; Neostriatum; Nerve Growth Factors; Neurites; Neurons; Neuropeptides; Neurotrophin 3; Rats; Rats, Sprague-Dawley; Serotonin; Tetrodotoxin; Theophylline | 1996 |
Studies on the roles of ATP, adenosine and nitric oxide in mediating muscle vasodilatation induced in the rat by acute systemic hypoxia.
Topics: 5'-Nucleotidase; Acute Disease; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Enzyme Inhibitors; Hypoxia; Male; Muscle, Skeletal; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Oxygen Consumption; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Regional Blood Flow; Theophylline; Vasodilation | 1996 |
Release of adenosine from human sensitized lung fragments and its effect on antigen-induced mediator release.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Antigens; Guinea Pigs; Histamine Release; Humans; Immunization; In Vitro Techniques; Leukotrienes; Lung; Mast Cells; Theophylline | 1996 |
Integration of vascular, contractile and metabolic responses to hypoxia: effects of maturation and adenosine.
Topics: Adenosine; Aging; Animals; Coronary Circulation; Coronary Vessels; Energy Metabolism; Heart; Hemodynamics; Hypoxia; In Vitro Techniques; Myocardial Contraction; Myocardium; Rabbits; Theophylline | 1996 |
Attenuated purine production during subsequent ischemia in preconditioned rabbit myocardium is unrelated to the mechanism of protection.
Topics: Adenosine; Animals; Female; Heart; Hemodynamics; Hypoxanthines; In Vitro Techniques; Inosine; Ischemic Preconditioning, Myocardial; Male; Myocardial Ischemia; Myocardium; Phenylephrine; Purinergic P1 Receptor Antagonists; Purines; Rabbits; Receptors, Purinergic P1; Theophylline | 1996 |
Role of adenosine receptor subtypes in neural stunning of sympathetic coronary innervation.
Topics: Adenosine; Animals; Coronary Vessels; Dogs; Female; Male; Myocardial Stunning; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Sympathetic Nervous System; Theobromine; Theophylline; Vasoconstriction; Xanthines | 1997 |
Adenosine receptor blockade enhance glycolysis in hypoperfused guinea-pig myocardium.
Topics: Adenosine; Animals; Enzyme Activation; Glucose; Glycogen; Glycolysis; Guinea Pigs; In Vitro Techniques; Lactic Acid; Myocardial Ischemia; Myocardium; Oxidation-Reduction; Perfusion; Phosphofructokinase-1; Purinergic P1 Receptor Antagonists; Theophylline; Ventricular Function, Left | 1997 |
Adenosine release mediates cyanide-induced suppression of CA1 neuronal activity.
Topics: Adenosine; Animals; Dipyridamole; Evoked Potentials; Excitatory Postsynaptic Potentials; Glyburide; Hippocampus; In Vitro Techniques; Male; Neurons; Potassium Cyanide; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Synapses; Theophylline; Xanthines | 1997 |
Adenosine analogues relax guinea-pig taenia caeci via an adenosine A2B receptor and a xanthine-resistant site.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Cecum; Dose-Response Relationship, Drug; Guinea Pigs; Male; Muscle Relaxation; Muscle, Smooth; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Theophylline; Triazines; Triazoles; Vasodilator Agents; Xanthines | 1997 |
Vesnarinone limits infarct size via adenosine-dependent mechanisms in the canine heart.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Animals; Cardiotonic Agents; Dipyridamole; Dogs; Enzyme Activation; Enzyme Inhibitors; Infusions, Intra-Arterial; Ion Channel Gating; Myocardial Infarction; Myocardial Reperfusion Injury; Potassium Channels; Pyrazines; Quinolines; Receptors, Purinergic P1; Theophylline | 1997 |
Protection against global ischemia in the rabbit isolated heart 24 hours after transient adenosine A1 receptor activation.
Topics: Adenosine; Animals; Blood Pressure; In Vitro Techniques; Ischemic Preconditioning, Myocardial; Male; Myocardial Ischemia; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rabbits; Theophylline | 1997 |
The effect of age on adenosine A1 receptor function in the rat heart.
Topics: Adenosine; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Adrenergic beta-Agonists; Age Factors; Animals; Carbachol; Cardiovascular Agents; Cell Membrane; Colforsin; Heart; Isoproterenol; Male; Muscarinic Agonists; Myocardium; Purinergic P1 Receptor Agonists; Rats; Rats, Inbred F344; Receptors, Purinergic P1; Sulfonic Acids; Theophylline | 1997 |
Endogenous adenosine on membrane properties of CA1 neurons in rat hippocampal slices during normoxia and hypoxia.
Topics: Adenosine; Adenosine Deaminase; Animals; Electric Stimulation; Hippocampus; Hypoxia; In Vitro Techniques; Membrane Potentials; Neurons; Patch-Clamp Techniques; Potassium Channels; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Synapses; Theophylline | 1997 |
Transgenic A1 adenosine receptor overexpression increases myocardial resistance to ischemia.
Topics: Adenosine; Analysis of Variance; Animals; Cell Membrane; Coronary Vessels; Female; Heart; Heart Rate; In Vitro Techniques; Male; Mice; Mice, Transgenic; Myocardial Contraction; Myocardial Ischemia; Myocardial Reperfusion; Myocardium; Myosin Heavy Chains; Promoter Regions, Genetic; Radioligand Assay; Rats; Receptors, Purinergic P1; Recombinant Fusion Proteins; Theophylline; Vascular Resistance | 1997 |
A role for adenosine A2 receptors in the induction of long-term potentiation in the CA1 region of rat hippocampus.
Topics: Adenosine; Animals; Hippocampus; Long-Term Potentiation; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Synaptic Transmission; Theobromine; Theophylline | 1997 |
Dilazep, an antiplatelet agent, inhibits tissue factor expression in endothelial cells and monocytes.
Topics: Adenosine; Dilazep; Endothelium, Vascular; Gene Expression; Humans; Monocytes; Platelet Aggregation Inhibitors; Purinergic P1 Receptor Agonists; Tetradecanoylphorbol Acetate; Theophylline; Thrombin; Thromboplastin; Tumor Necrosis Factor-alpha | 1997 |
Involvement of functional antagonism in the effects of adenosine antagonists and L-NAME in the rat isolated heart.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adrenergic alpha-Agonists; Animals; Anti-Arrhythmia Agents; Enzyme Inhibitors; Heart; Heart Atria; In Vitro Techniques; Male; Myocardial Contraction; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; Phenethylamines; Phenylephrine; Purinergic P1 Receptor Antagonists; Purines; Rats; Rats, Wistar; Sulfonamides; Theophylline; Vasodilator Agents | 1997 |
Importance of endogenous adenosine during ischemia and reperfusion in neonatal porcine hearts.
Topics: Adenosine; Animals; Animals, Newborn; Creatine Kinase; Myocardial Contraction; Myocardial Ischemia; Myocardial Reperfusion; Piperazines; Swine; Theophylline | 1997 |
Use of a newly developed technique to isolate rat pinealocytes and study the effects of adenosine agonists on melatonin production.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Cell Separation; Dose-Response Relationship, Drug; Isoproterenol; Male; Melatonin; Phenethylamines; Pineal Gland; Radioimmunoassay; Rats; Rats, Wistar; Theophylline | 1997 |
Activation of two sites by adenosine receptor agonists to cause relaxation in rat isolated mesenteric artery.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Anti-Arrhythmia Agents; Dinucleoside Phosphates; Dose-Response Relationship, Drug; Male; Mesenteric Arteries; Purinergic P1 Receptor Agonists; Rats; Rats, Wistar; Receptors, Purinergic P1; Theophylline; Triazines; Triazoles; Vasodilation; Vasodilator Agents | 1997 |
Effects of ischemic preconditioning on contractile and metabolic function during hypoperfusion in dogs.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Animals; Blood Flow Velocity; Coronary Circulation; Coronary Vessels; Dogs; Enzyme Inhibitors; Hydrogen-Ion Concentration; Ischemic Preconditioning, Myocardial; Lactic Acid; Myocardial Contraction; Myocardium; Purinergic P1 Receptor Antagonists; Theophylline | 1998 |
Effect of aging on A1-adenosine receptor-mediated inhibition of norepinephrine release in the rat heart.
Topics: Adenosine; Adenosine Deaminase; Aging; Animals; Heart; Male; Myocardium; Norepinephrine; Rats; Rats, Inbred F344; Receptors, Purinergic P1; Synaptosomes; Theophylline | 1998 |
Low concentrations of adenosine receptor blocker decrease protection by hypoxic preconditioning in ischemic rat hearts.
Topics: Adenosine; Adenosine Triphosphate; Animals; Creatine Kinase; Hypoxia; In Vitro Techniques; Ischemic Preconditioning, Myocardial; L-Lactate Dehydrogenase; Lactic Acid; Male; Myocardial Reperfusion Injury; Perfusion; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Theophylline; Ventricular Function, Left | 1998 |
Endogenous adenosine inhibits P-selectin-dependent formation of coronary thromboemboli during hypoperfusion in dogs.
Topics: Adenosine; Animals; Antibodies, Monoclonal; Blood Platelets; Cell Adhesion; Coronary Circulation; Coronary Thrombosis; Dogs; Female; Male; Neutrophils; P-Selectin; Platelet Adhesiveness; Purinergic P1 Receptor Antagonists; Theophylline; Thromboembolism | 1998 |
Role of adenosine and its receptors in the vasodilatation induced in the cerebral cortex of the rat by systemic hypoxia.
Topics: Adenosine; Animals; Blood Flow Velocity; Blood-Brain Barrier; Erythrocytes; Hypoxia; Laser-Doppler Flowmetry; Male; Parietal Lobe; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptors, Purinergic P1; Theophylline; Triazines; Triazoles; Vasodilation | 1998 |
Antagonism of an adenosine/ATP receptor in follicular Xenopus oocytes.
Topics: Adenosine; Adenosine Triphosphate; Animals; Dose-Response Relationship, Drug; Follicle Stimulating Hormone; Oocytes; Potassium Channels; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2; Theophylline; Xenopus laevis | 1998 |
Cyclopentyladenosine-induced homologous down-regulation of A1 adenosine receptors (A1AR) in intact neurons is accompanied by receptor sequestration but not a reduction in A1AR mRNA expression or G protein alpha-subunit content.
Topics: Adenosine; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Cells, Cultured; Cerebellum; Down-Regulation; Gene Expression; GTP-Binding Protein alpha Subunits, Gs; Neurons; Purinergic P1 Receptor Agonists; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; RNA, Messenger; Theophylline; Tritium; Xanthines | 1998 |
Modulatory role of endothelium-derived relaxing factors on the flow-regulated coronary vascular resistance.
Topics: Adenosine; Animals; Coronary Vessels; Guinea Pigs; In Vitro Techniques; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Perfusion; Purinergic P1 Receptor Antagonists; Regional Blood Flow; Theophylline; Vascular Resistance | 1998 |
Optimal myocardial preconditioning in a human model of ischemia and reperfusion.
Topics: Adenosine; Dose-Response Relationship, Drug; Humans; Ischemic Preconditioning, Myocardial; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Protein Kinase C; Purinergic P1 Receptor Antagonists; Theophylline | 1998 |
Adenosine A2A receptors inhibit the conductance of NMDA receptor channels in rat neostriatal neurons.
Topics: Adenosine; Adenylyl Cyclases; Animals; Caffeine; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; In Vitro Techniques; Neostriatum; Neurons; Patch-Clamp Techniques; Phenethylamines; Purinergic P1 Receptor Agonists; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Purinergic P1; Signal Transduction; Theophylline | 1998 |
Involvement of P1 receptors in the effect of forskolin on cyclic AMP accumulation and export in PC12 cells.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Colforsin; Cyclic AMP; PC12 Cells; Probenecid; Purinergic P1 Receptor Antagonists; Rats; Receptors, Purinergic P1; Theophylline; Time Factors | 1999 |
Plasma adenosine levels and platelet activation in patients with atrial fibrillation.
Topics: Adenosine; Adult; Atrial Fibrillation; Case-Control Studies; Female; Humans; Male; Middle Aged; P-Selectin; Platelet Activation; Receptors, Purinergic P1; Theophylline | 1999 |
A novel influence of adenosine on ongoing activity in rat rostral ventrolateral medulla.
Topics: Adenosine; Animals; Antihypertensive Agents; Bicuculline; Electric Stimulation; GABA Antagonists; Hypothalamus; Male; Medulla Oblongata; Neurons; Phenethylamines; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Theophylline; Xanthines | 1999 |
Amplification of the cyclic AMP response to forskolin in pheochromocytoma PC12 cells through adenosine A(2A) purinoceptors.
Topics: Adenosine; Adenosine Deaminase; Adenosine Monophosphate; Animals; Colforsin; Cyclic AMP; Inosine; Kinetics; PC12 Cells; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Purines; Rats; Receptor, Adenosine A2A; Receptors, Purinergic P1; Sulfonamides; Theophylline | 1999 |
Optimal myocardial preconditioning in humans.
Topics: Adenosine; Adenosine Triphosphate; Cells, Cultured; Coronary Artery Bypass; Energy Metabolism; Heart Ventricles; Humans; Ischemic Preconditioning, Myocardial; Lactic Acid; Myocardium; Purinergic P1 Receptor Antagonists; Theophylline | 1999 |
Contributions of adenosine receptor activation to the ocular actions of epinephrine.
Topics: Adenosine; Adrenergic Agonists; Animals; Aqueous Humor; Epinephrine; Inosine; Intraocular Pressure; Ophthalmic Solutions; Pupil; Purinergic P1 Receptor Antagonists; Rabbits; Receptors, Purinergic P1; Theobromine; Theophylline | 1999 |
Role of peripheral adenosine A(1) receptors in the regulation of sleep apneas in rats.
Topics: Adenosine; Animals; Blood Pressure; Dose-Response Relationship, Drug; Male; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Respiration; Sleep Apnea Syndromes; Sleep Stages; Theophylline | 1999 |
Elevated levels of endogenous adenosine alter metabolism and enhance reduction in contractile function during low-flow ischemia: associated changes in expression of Ca(2+)-ATPase and phospholamban.
Topics: Adenosine; Animals; Calcium-Binding Proteins; Calcium-Transporting ATPases; Cardiotonic Agents; Energy Metabolism; Female; Gene Expression Regulation; Heart; In Vitro Techniques; Male; Myocardial Contraction; Myocardial Ischemia; Myocardial Reperfusion; Myocardium; Oxygen Consumption; Piperazines; Swine; Theophylline; Ventricular Function, Left | 1999 |
Ischemic preconditioning and glucose metabolism during low-flow ischemia: role of the adenosine A1 receptor.
Topics: Adenosine; Animals; Glucose; Glycolysis; Ischemic Preconditioning, Myocardial; Male; Myocardial Ischemia; Myocardium; Perfusion; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Regional Blood Flow; Theophylline | 1999 |
Adenosine is not responsible for local metabolic control of coronary blood flow in dogs during exercise.
Topics: Adenosine; Animals; Coronary Circulation; Dogs; Dose-Response Relationship, Drug; Male; Motor Activity; Purinergic P1 Receptor Antagonists; Pyridines; Receptors, Endothelin; Tetrazoles; Theophylline | 2000 |
Adenosine primes the opening of mitochondrial ATP-sensitive potassium channels: a key step in ischemic preconditioning?
Topics: Adenosine; Animals; Decanoic Acids; Diazoxide; Enzyme Inhibitors; Flavoproteins; Hydroxy Acids; Ischemic Preconditioning; Membrane Proteins; Oxidation-Reduction; Polymyxin B; Potassium Channels; Protein Kinase C; Purinergic P1 Receptor Antagonists; Rabbits; Theophylline; Time Factors | 2000 |
Adenosine receptor blockade reveals N-methyl-D-aspartate receptor- and voltage-sensitive dendritic spikes in rat hippocampal CA1 pyramidal cells in vitro.
Topics: Action Potentials; Adenosine; Animals; Dendrites; Drug Synergism; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Hippocampus; In Vitro Techniques; Male; Membrane Potentials; Purinergic P1 Receptor Antagonists; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission; Theophylline | 2000 |
Interdependence of adenosine and nitric oxide in hepato-splanchnic circulation during sepsis.
Topics: Adenosine; Animals; Liver Circulation; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Sprague-Dawley; Sepsis; Splanchnic Circulation; Theophylline | 2000 |
Characterisation of adenosine receptors mediating relaxation in hamster isolated aorta.
Topics: 2-Chloroadenosine; Adenosine; Animals; Aorta; Cricetinae; Dose-Response Relationship, Drug; In Vitro Techniques; Male; Mesocricetus; NG-Nitroarginine Methyl Ester; Nitric Oxide; Phenethylamines; Receptors, Purinergic P1; Theophylline; Thioinosine; Vasodilation | 2000 |
Role of adenosine and glycogen in ischemic preconditioning of rat hearts.
Topics: Adenosine; Adenosine Triphosphate; Animals; Glycogen; Hydrogen-Ion Concentration; Ischemic Preconditioning, Myocardial; Male; Myocardium; Phosphates; Phosphocreatine; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Theophylline | 2001 |
Plasma adenosine levels and P-selectin expression on platelets in preeclampsia.
Topics: Adenosine; Adult; Case-Control Studies; Female; Humans; P-Selectin; Platelet Activation; Pre-Eclampsia; Pregnancy; Theophylline | 2001 |
Differential effects of UTP, ATP, and adenosine on ciliary activity of human nasal epithelial cells.
Topics: Adenosine; Adenosine Triphosphate; Adenosine-5'-(N-ethylcarboxamide); Antineoplastic Agents; Cilia; Cyclic AMP; Dose-Response Relationship, Drug; Epithelial Cells; Humans; Nasal Mucosa; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2; Receptors, Purinergic P2Y1; Receptors, Purinergic P2Y2; Theophylline; Uridine Triphosphate | 2001 |
Identification of two distinct vasodilator pathways activated by ATP in the mesenteric bed of the rat.
Topics: Adenine; Adenosine; Adenosine Triphosphate; Animals; Arachidonic Acids; Capsaicin; Dose-Response Relationship, Drug; Endocannabinoids; Endothelium, Vascular; Enzyme Inhibitors; Guanylate Cyclase; Histamine; In Vitro Techniques; Male; Mesenteric Arteries; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Oxadiazoles; Piperidines; Polyunsaturated Alkamides; Potassium Chloride; Pyrazoles; Pyrilamine; Quinoxalines; Rats; Rats, Wistar; Rimonabant; Signal Transduction; Stereoisomerism; Theophylline; Vasodilation | 2001 |
Role of adenosine in ischemic preconditioning in rats depends critically on the duration of the stimulus and involves both A(1) and A(3) receptors.
Topics: Acetamides; Adenosine; Analysis of Variance; Animals; Cryoprotective Agents; Dihydropyridines; Histamine H1 Antagonists; Ischemic Preconditioning, Myocardial; Male; Myocardial Infarction; Purinergic Antagonists; Purinergic P1 Receptor Antagonists; Pyrilamine; Rats; Rats, Wistar; Receptors, Purinergic; Receptors, Purinergic P1; Theophylline; Time Factors | 2001 |
Cardioprotection with adenosine metabolism inhibitors in ischemic-reperfused mouse heart.
Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Adenosine Kinase; Animals; Enzyme Inhibitors; Female; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Myocardial Contraction; Myocardial Reperfusion Injury; Myocardium; Perfusion; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Theophylline; Tubercidin | 2001 |
Activation of adenosine A1 receptors by drugs to lower plasma glucose in streptozotocin-induced diabetic rats.
Topics: Adenosine; Animals; Blood Glucose; Cholesterol; Diabetes Mellitus, Experimental; Dipyridamole; Disease Models, Animal; Dose-Response Relationship, Drug; Glucose; Glycogen; Hypoglycemic Agents; Insulin; Male; Muscle, Skeletal; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptors, Purinergic P1; Streptozocin; Theophylline; Triglycerides; Xanthines | 2000 |
Purine nucleoside-dependent inhibition of cellular proliferation in 1321N1 human astrocytoma cells.
Topics: 2-Chloroadenosine; Adenosine; Adenosine Triphosphate; Astrocytoma; Brain Neoplasms; Cell Death; Cell Division; Humans; Purine Nucleosides; Purinergic P1 Receptor Antagonists; Theophylline; Tumor Cells, Cultured; Uridine Triphosphate | 2001 |
Adenosine-mediated hypotension in in vivo guinea-pig: receptors involved and role of NO.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Blood Pressure; Diphenhydramine; Dose-Response Relationship, Drug; Enzyme Inhibitors; Guinea Pigs; Heart Rate; Hypotension; Male; Methylene Blue; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Theophylline; Triazines; Triazoles; Vasodilator Agents; Xanthines | 2001 |
Role of adenosine and P2 receptors in the penile tumescence in anesthetized dogs.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Anesthesia; Animals; Dogs; Dose-Response Relationship, Drug; Enzyme Inhibitors; Injections, Intravenous; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Penile Erection; Penis; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2; Theophylline; Thionucleotides; Triazines; Triazoles | 2001 |
On the functional role of muscarinic M2 receptors in cholinergic and purinergic responses in the rat urinary bladder.
Topics: 2-Chloroadenosine; Adenosine; Adenosine Triphosphate; Animals; Carbachol; Diamines; Dose-Response Relationship, Drug; In Vitro Techniques; Male; Muscarinic Agonists; Muscarinic Antagonists; Muscle Contraction; Piperidines; Pirenzepine; Purinergic Agonists; Purinergic Antagonists; Rats; Rats, Sprague-Dawley; Receptor, Muscarinic M2; Receptors, Muscarinic; Receptors, Purinergic; Theophylline; Urinary Bladder | 2001 |
Role of adenosine in renal protection induced by a brief episode of ischemic preconditioning in rats.
Topics: Adenosine; Animals; Blood Pressure; Glomerular Filtration Rate; Heart Rate; Ischemia; Ischemic Preconditioning; Kidney; Male; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptors, Purinergic P1; Renal Artery Obstruction; Renal Circulation; Reperfusion Injury; Theobromine; Theophylline; Time Factors; Ultrasonography, Doppler, Pulsed; Xanthines | 2001 |
Nucleotide-evoked relaxation of rat vas deferens: possible mechanisms.
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Cyclic AMP; Dose-Response Relationship, Drug; In Vitro Techniques; Male; Muscle Relaxation; Nucleotides; Potassium; Rats; Rats, Wistar; Theophylline; Thionucleotides; Vas Deferens | 2002 |
Minoxidil-induced hair growth is mediated by adenosine in cultured dermal papilla cells: possible involvement of sulfonylurea receptor 2B as a target of minoxidil.
Topics: Adenosine; Adenosine Triphosphate; ATP-Binding Cassette Transporters; Calcium; Cells, Cultured; Dermis; DNA Primers; Endothelial Growth Factors; Gene Expression; Hair; Humans; Hypertrichosis; Lymphokines; Minoxidil; Potassium Channels; Potassium Channels, Inwardly Rectifying; Purinergic P1 Receptor Antagonists; Receptors, Drug; Receptors, Purinergic P1; Sulfonylurea Receptors; Theobromine; Theophylline; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors; Vasodilator Agents | 2001 |
Complementary role of extracellular ATP and adenosine in ischemic preconditioning in the rat heart.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Coloring Agents; Extracellular Space; Ischemic Preconditioning; Male; Microdialysis; Organic Chemicals; Purinergic P1 Receptor Antagonists; Purinergic P2 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Receptors, Purinergic P2; Suramin; Theophylline; Ventricular Function, Left; Ventricular Pressure | 2002 |
Sites of action of adenosine in interorgan preconditioning of the heart.
Topics: Adenosine; Animals; Blood Pressure; Coronary Vessels; Ganglionic Blockers; Heart Rate; Hexamethonium; Injections, Intra-Arterial; Injections, Intravenous; Intestine, Small; Ischemia; Ischemic Preconditioning, Myocardial; Male; Mesenteric Arteries; Mesentery; Myocardial Infarction; Myocardial Ischemia; Myocardium; Portal Vein; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptors, Purinergic P1; Theophylline | 2002 |
A1 adenosine receptor activation induces ventriculomegaly and white matter loss.
Topics: Adenosine; Animals; Animals, Newborn; Body Weight; Cell Count; Cerebral Cortex; Cerebral Ventricles; Drug Combinations; Drug Interactions; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Hippocampus; Microscopy, Electron; Myelin Basic Protein; Nerve Degeneration; Nerve Fibers, Myelinated; Neuroglia; Neurons; Presynaptic Terminals; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Telencephalon; Theophylline | 2002 |
Interactions of adenosine, prostaglandins and nitric oxide in hypoxia-induced vasodilatation: in vivo and in vitro studies.
Topics: Adenosine; Animals; Aorta; Cyclooxygenase Inhibitors; Diclofenac; Hypoxia; In Vitro Techniques; Indomethacin; Male; Muscle, Skeletal; Nitric Oxide; Prostaglandins; Rats; Rats, Wistar; Theophylline; Vasodilation | 2002 |
Adenosine uptake inhibition ameliorates cerulein-induced acute pancreatitis in mice.
Topics: Acute Disease; Adenosine; Amylases; Animals; Biological Transport; Ceruletide; Dipyridamole; Female; Lipase; Mice; Mice, Inbred BALB C; Models, Chemical; Pancreatitis; Piperazines; Pyrimidinones; Quinazolines; Theophylline | 2002 |
Purinergic modulation of neuronal activity in the mesolimbic dopaminergic system in vivo.
Topics: Adenosine; Adenosine Triphosphate; Animals; Dopamine; Electroencephalography; Male; Microdialysis; Neurons; Nucleus Accumbens; Purinergic P1 Receptor Antagonists; Purinergic P2 Receptor Antagonists; Purines; Pyridoxal Phosphate; Rats; Rats, Wistar; Receptors, Purinergic P1; Receptors, Purinergic P2; Theophylline; Thionucleotides; Ventral Tegmental Area | 2003 |
Resveratrol provides late-phase cardioprotection by means of a nitric oxide- and adenosine-mediated mechanism.
Topics: Adenosine; Animals; Cardiotonic Agents; Coronary Circulation; Enzyme Inhibitors; Heart; In Vitro Techniques; Male; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Resveratrol; Stilbenes; Theophylline; Time Factors; Vasodilator Agents | 2003 |
Adenosine mediates decreased cerebral metabolic rate and increased cerebral blood flow during acute moderate hypoxia in the near-term fetal sheep.
Topics: Adenosine; Animals; Blood Flow Velocity; Blood Gas Analysis; Blood Glucose; Brain; Cerebrovascular Circulation; Energy Metabolism; Fetal Hypoxia; Gestational Age; Hemoglobins; Infusions, Intravenous; Lactic Acid; Oxyhemoglobins; Purinergic P1 Receptor Antagonists; Sheep; Theophylline; Xanthines | 2003 |
Cardiovascular effects of the adenosine A1 receptor agonist N6-cyclopentyladenosine (CPA) decisive for its therapeutic efficacy in sarin poisoning.
Topics: Adenosine; Animals; Bradycardia; Chemical Warfare Agents; Dose-Response Relationship, Drug; Drug Antagonism; Drug Therapy, Combination; Heart Diseases; Hypotension; Injections, Intramuscular; Male; Poisoning; Purinergic P1 Receptor Agonists; Rats; Sarin; Theophylline | 2004 |
Methotrexate and MX-68, a new derivative of methotrexate, limit infarct size via adenosine-dependent mechanisms in canine hearts.
Topics: 2-Aminoadipic Acid; Adenosine; Animals; Cardiotonic Agents; Dogs; Methotrexate; Myocardial Infarction; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Theophylline | 2004 |
Role of central and peripheral adenosine receptors in the cardiovascular responses to intraperitoneal injections of adenosine A1 and A2A subtype receptor agonists.
Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Animals; Blood Pressure; Caffeine; Heart Rate; Injections, Intraperitoneal; Male; Phenethylamines; Rats; Rats, Sprague-Dawley; Theophylline; Xanthines | 2005 |
The influence of hypothermia on P2 receptor-mediated responses of frog skeletal muscle.
Topics: Action Potentials; Adenosine; Adenosine Triphosphate; Analysis of Variance; Animals; Dose-Response Relationship, Drug; Electric Stimulation; In Vitro Techniques; Muscle Contraction; Muscle, Skeletal; Potassium Chloride; Purinergic P1 Receptor Antagonists; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Rana ridibunda; Receptors, Purinergic P1; Receptors, Purinergic P2; Suramin; Temperature; Theophylline | 2005 |
Alpha1-receptor or adenosine A1-receptor dependent pathway alone is not sufficient but summation of these pathways is required to achieve an ischaemic preconditioning effect in rabbits.
Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Antagonists; Animals; Blood Pressure; Enzyme Inhibitors; Heart Rate; Ischemic Preconditioning, Myocardial; Male; Myocardial Infarction; Protein Kinase C; Quinazolines; Rabbits; Receptor, Adenosine A1; Receptors, Adrenergic, alpha-1; Staurosporine; Theophylline; Tyramine; Vasodilator Agents | 2005 |
Adenosinergic modulation of ventilation in obese zucker rats.
Topics: Adenosine; Aminophylline; Animals; Carbon Dioxide; Hypercapnia; Hypoxia; Male; Obesity; Oxygen; Oxygen Consumption; Rats; Rats, Zucker; Respiration; Theophylline | 2005 |
Postconditioning reduces infarct size via adenosine receptor activation by endogenous adenosine.
Topics: Adenosine; Animals; Male; Myocardial Infarction; Myocardial Reperfusion; Myocardium; Perfusion; Purinergic P1 Receptor Antagonists; Random Allocation; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Theophylline; Triazines; Triazoles; Xanthines | 2005 |
A calcium channel blocker amlodipine increases coronary blood flow via both adenosine- and NO-dependent mechanisms in ischemic hearts.
Topics: Adenosine; Amlodipine; Animals; Calcium Channel Blockers; Coronary Circulation; Coronary Vessels; Dogs; Myocardial Ischemia; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide; Superoxide Dismutase; Theophylline; Vasodilator Agents | 2005 |
Acute dilatory and negative inotropic effects of homocysteine are inhibited by an adenosine blocker.
Topics: Acetylcholine; Adenosine; Animals; Anti-Arrhythmia Agents; Atropine; Calcium Channel Blockers; Coronary Circulation; Dose-Response Relationship, Drug; Heart Rate; Homocysteine; In Vitro Techniques; Male; Muscle Contraction; Muscle Tonus; Muscle, Smooth, Vascular; Myocardial Contraction; Nifedipine; Rats; Rats, Sprague-Dawley; Theophylline; Vasodilation; Vasodilator Agents | 2006 |
The role of adenosine in the early respiratory and cardiovascular changes evoked by chronic hypoxia in the rat.
Topics: Adenosine; Animals; Blood Pressure; Cardiovascular System; Enzyme Inhibitors; Guanidines; Heart Rate; Hemodynamics; Hypoxia; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Rats; Rats, Wistar; Receptor, Adenosine A1; Respiration; Respiratory Function Tests; Theophylline; Xanthines | 2006 |
Regional vascular responses to ATP and ATP analogues in the rabbit kidney in vivo: roles for adenosine receptors and prostanoids.
Topics: Adenosine; Adenosine Triphosphate; Animals; Cyclooxygenase Inhibitors; Ibuprofen; Kidney; Kidney Cortex; Kidney Medulla; Laser-Doppler Flowmetry; Male; Nitric Oxide Synthase; Nitroarginine; Prostaglandins; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Rabbits; Receptors, Purinergic P1; Receptors, Purinergic P2; Regional Blood Flow; Renal Circulation; Theophylline | 2006 |
The impact of hypoxia on in vivo glucose uptake in a hypoglycemic fish, Myoxocephalus scorpius.
Topics: Adenosine; Animals; Atropine; Blood Glucose; Brain Chemistry; Carbohydrate Metabolism; Cardiac Output; Deoxyglucose; Extracellular Fluid; Fishes; Glucose; Glucose-6-Phosphate; Heart Rate; Hypoxia; Lactic Acid; Muscarinic Antagonists; Phosphorylation; Purinergic P1 Receptor Antagonists; Theophylline; Tissue Distribution | 2007 |
Modulation of ischaemic contracture in mouse hearts: a 'supraphysiological' response to adenosine.
Topics: 2-Chloroadenosine; Adenine; Adenosine; Animals; In Vitro Techniques; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Myocardial Contraction; Myocardial Reperfusion Injury; Receptor, Adenosine A1; Theophylline; Time Factors; Ventricular Function, Left; Ventricular Pressure; Xanthines | 2007 |
Hypotensive effects of intravenously administered uridine and cytidine in conscious rats: involvement of adenosine receptors.
Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A2 Receptor Agonists; Animals; Antihypertensive Agents; Blood Pressure; Caffeine; Carotid Arteries; Consciousness; Cytidine; Dose-Response Relationship, Drug; Heart Rate; Hypotension; Injections, Intravenous; Injections, Intraventricular; Male; Rats; Rats, Wistar; Receptor, Adenosine A1; Receptor, Adenosine A2A; Theobromine; Theophylline; Time Factors; Triazines; Triazoles; Uridine; Ventricular Function, Left; Ventricular Pressure; Xanthines | 2008 |
Modulation of murine dendritic cell function by adenine nucleotides and adenosine: involvement of the A(2B) receptor.
Topics: Acetamides; Adenine Nucleotides; Adenosine; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Adenosine-5'-(N-ethylcarboxamide); Animals; Antigens, Surface; Arginase; Cyclic AMP; Cytokines; Dendritic Cells; Gene Expression; Gene Expression Profiling; Interleukin-12; Lipopolysaccharides; Mice; Mice, Inbred C57BL; Mice, Knockout; Nitrites; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Purines; Receptor, Adenosine A2A; Receptor, Adenosine A2B; Receptors, Purinergic P1; Signal Transduction; Theophylline | 2008 |
N-methyl-D-aspartic acid causes relaxation of porcine retinal arterioles through an adenosine receptor-dependent mechanism.
Topics: 2-Amino-5-phosphonovalerate; Adenosine; Adenosine Triphosphate; Animals; Arterioles; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Hydrolysis; Muscle, Smooth, Vascular; N-Methylaspartate; Purinergic P1 Receptor Antagonists; Receptors, N-Methyl-D-Aspartate; Receptors, Purinergic P1; Retinal Artery; Swine; Theophylline; Vasodilation | 2008 |
Intermittent adenosine at the beginning of reperfusion does not trigger cardioprotection.
Topics: Adenosine; Animals; In Vitro Techniques; Male; Myocardial Reperfusion Injury; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Theophylline; Vasodilator Agents | 2009 |
Adenosine as an endogenous regulating factor of hippocampal sharp waves.
Topics: Adenine; Adenosine; Adenosine A1 Receptor Antagonists; Animals; Dizocilpine Maleate; Electric Stimulation; Excitatory Postsynaptic Potentials; Hippocampus; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Membrane Potentials; Mice; Mice, Inbred C57BL; Microelectrodes; Nucleoside Transport Proteins; Patch-Clamp Techniques; Pyramidal Cells; Quinoxalines; Receptor, Adenosine A1; Receptors, N-Methyl-D-Aspartate; Theophylline; Xanthines | 2009 |
Activation of NTS A2a adenosine receptors differentially resets baroreflex control of renal vs. adrenal sympathetic nerve activity.
Topics: Adenosine; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Adrenal Glands; Animals; Antihypertensive Agents; Baroreflex; Blood Pressure; Heart Rate; Kidney; Male; Phenethylamines; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A1; Receptor, Adenosine A2A; Solitary Nucleus; Sympathetic Nervous System; Theophylline; Triazines; Triazoles | 2009 |
Elucidation in the rat of the role of adenosine and A2A-receptors in the hyperaemia of twitch and tetanic contractions.
Topics: Adenosine; Adenosine A2 Receptor Antagonists; Animals; Blood Pressure; Carbon Dioxide; Electric Stimulation; Femoral Artery; Hydrogen-Ion Concentration; Hyperemia; Isometric Contraction; Male; Muscle, Skeletal; Muscle, Smooth, Vascular; Oxygen; Rats; Rats, Wistar; Receptor, Adenosine A2A; Regional Blood Flow; Sciatic Nerve; Theophylline; Time Factors; Triazines; Triazoles; Vasodilation | 2009 |
Interaction of hydrocortisone with ATP and adenosine on nerve-mediated contractions of frog skeletal muscle.
Topics: Adenosine; Adenosine Triphosphate; Animals; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Hydrocortisone; Muscle Contraction; Muscle, Skeletal; Neuromuscular Junction; Purinergic P1 Receptor Antagonists; Purinergic P2 Receptor Antagonists; Pyridoxal Phosphate; Rana ridibunda; Theophylline; Time Factors | 2009 |
Metformin prevents myocardial reperfusion injury by activating the adenosine receptor.
Topics: Adenosine; Animals; Biological Transport; Hypoglycemic Agents; In Vitro Techniques; Male; Metformin; Myocardial Infarction; Myocardial Reperfusion Injury; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Theophylline; Thioinosine | 2009 |
Sphingosine 1-phosphate is an important endogenous cardioprotectant released by ischemic pre- and postconditioning.
Topics: Adenosine; Animals; Animals, Newborn; Cells, Cultured; In Vitro Techniques; Ischemic Preconditioning, Myocardial; Lysophospholipids; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; Myocytes, Cardiac; Perfusion; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Lysosphingolipid; Receptors, Purinergic P1; Recovery of Function; Signal Transduction; Sphingosine; Theophylline; Time Factors; Ventricular Function, Left; Ventricular Pressure | 2009 |
Estimation of endogenous adenosine activity at adenosine receptors in guinea-pig ileum using a new pharmacological method.
Topics: 2-Chloroadenosine; Adenosine; Animals; Dilazep; Dose-Response Relationship, Drug; Guinea Pigs; Ileum; Male; Muscle Contraction; Receptors, Purinergic P1; Synaptic Transmission; Theophylline; Vasodilator Agents | 2010 |
A distinct nitric oxide and adenosine A1 receptor dependent hepatic artery vasodilatatory response in the CCl-cirrhotic liver.
Topics: Adenosine; Adenosine A1 Receptor Antagonists; Animals; Blotting, Western; Caffeine; Carbon Tetrachloride; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Hepatic Artery; Liver Cirrhosis, Experimental; Male; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Perfusion; Portal Vein; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A1; Receptor, Adenosine A2A; Theophylline; Vascular Resistance; Vasodilation; Vasodilator Agents | 2010 |
Hypoxia enhances the relaxing influence of perivascular adipose tissue in isolated mice aorta.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine; Adipose Tissue; Animals; Aorta, Thoracic; Arteries; Cell Hypoxia; Dinoprost; Glyburide; Guanylate Cyclase; Male; Mice; Norepinephrine; Potassium; Prostaglandins; Receptors, Cytoplasmic and Nuclear; Soluble Guanylyl Cyclase; Sulfides; Tetraethylammonium; Theophylline; Vasodilation | 2010 |
Metabolic regulation of coronary vascular tone: role of hydrogen peroxide, purinergic components, and angiotensin.
Topics: Adenosine; Adenosine Diphosphate; Angiotensin Receptor Antagonists; Angiotensins; Animals; Arterioles; Catalase; Coronary Vessels; Hydrogen Peroxide; Imidazoles; In Vitro Techniques; Lactic Acid; Male; Myocytes, Cardiac; Oxygen; Purinergic P1 Receptor Antagonists; Purinergic P2Y Receptor Antagonists; Rats; Rats, Wistar; Superoxides; Tetrazoles; Theophylline; Vascular Resistance; Vasoconstriction; Vasodilation | 2010 |
Endogenous adenosine A1 receptor activation underlies the transient post-ischemic rhythmic delta EEG activity.
Topics: Adenosine; Adenosine A1 Receptor Antagonists; Animals; Delta Rhythm; Disease Models, Animal; Electrocardiography; Electroencephalography; Heart Rate; Ischemic Attack, Transient; Male; Rats; Rats, Wistar; Receptor, Adenosine A1; Statistics, Nonparametric; Theophylline; Xanthines | 2011 |
Effects of maternal hypoxia on muscle vasodilatation evoked by acute systemic hypoxia in adult rat offspring: changed roles of adenosine and A1 receptors.
Topics: Adenosine; Adenosine A1 Receptor Antagonists; Animals; Bradycardia; Endothelium, Vascular; Female; Hypoxia; Male; Muscle, Skeletal; Pregnancy; Prenatal Exposure Delayed Effects; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptor, Adenosine A1; Theophylline; Vasodilation; Xanthines | 2010 |
Regulation of sFlt-1 and VEGF secretion by adenosine under hypoxic conditions in rat placental villous explants.
Topics: Adenosine; Animals; Chorionic Villi; Enzyme-Linked Immunosorbent Assay; Female; Hypoxia; Placenta; Pregnancy; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Theophylline; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-1 | 2010 |
Remote ischaemic preconditioning by brief hind limb ischaemia protects against renal ischaemia-reperfusion injury: the role of adenosine.
Topics: Adenosine; Animals; Hindlimb; Ischemic Preconditioning; Kidney; Male; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Theophylline | 2011 |
Cilostazol protects the heart against ischaemia reperfusion injury in a rabbit model of myocardial infarction: focus on adenosine, nitric oxide and mitochondrial ATP-sensitive potassium channels.
Topics: Adenosine; Animals; Cardiotonic Agents; Cilostazol; Decanoic Acids; Disease Models, Animal; Drug Evaluation, Preclinical; Enzyme Inhibitors; Humans; Hydroxy Acids; Myocardial Infarction; NG-Nitroarginine Methyl Ester; Nitric Oxide; Potassium Channel Blockers; Purinergic P1 Receptor Antagonists; Rabbits; Reperfusion Injury; Superoxides; Tetrazoles; Theophylline | 2011 |
Adenosine and opioid receptors do not trigger the cardioprotective effect of mild hypothermia.
Topics: Adenosine; Analgesics, Opioid; Animals; Fluorocarbons; Hypothermia, Induced; Morphine; Myocardial Infarction; Naloxone; Narcotic Antagonists; Purinergic P1 Receptor Antagonists; Rabbits; Receptors, Opioid; Receptors, Purinergic P1; Theophylline; Time Factors | 2012 |
Opposite effect of ATP on contraction force of tonic and phasic skeletal muscles in frogs.
Topics: Adenosine; Adenosine Triphosphate; Animals; Calcium; Muscle Contraction; Muscle Fibers, Skeletal; Muscle, Skeletal; Rana ridibunda; Receptors, Purinergic P1; Signal Transduction; Suramin; Theophylline | 2011 |
Activation of NTS A(1) adenosine receptors inhibits regional sympathetic responses evoked by activation of cardiopulmonary chemoreflex.
Topics: Adenosine; Animals; Biguanides; Blood Pressure; Cardiovascular Physiological Phenomena; Chemoreceptor Cells; Dose-Response Relationship, Drug; Feedback, Physiological; Heart Rate; Lung; Male; Models, Animal; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A1; Serotonin Receptor Agonists; Solitary Nucleus; Sympathetic Nervous System; Theophylline | 2012 |
Acute intravenous infusion of an adenosine regulating agent improves left ventricular function in dogs with advanced heart failure.
Topics: Adenosine; Aminoimidazole Carboxamide; Animals; Deoxyribonucleosides; Dogs; Heart Failure; Hemodynamics; Infusions, Intravenous; Purinergic P1 Receptor Antagonists; Theophylline; Ventricular Function, Left | 2013 |
Remote cardioprotection by transfer of coronary effluent from ischemic preconditioned rabbit heart preserves mitochondrial integrity and function via adenosine receptor activation.
Topics: Adenosine; Animals; Disease Models, Animal; Ischemic Preconditioning, Myocardial; Male; Mitochondria; Myocardial Infarction; Myocardial Reperfusion Injury; Rabbits; Reactive Oxygen Species; Receptors, Purinergic P1; Theophylline | 2014 |
Metabolic hyperemia requires ATP-sensitive K+ channels and H2O2 but not adenosine in isolated mouse hearts.
Topics: Adenosine; Adenosine A2 Receptor Antagonists; Animals; Coronary Circulation; Free Radical Scavengers; Glyburide; Heart; Hydrogen Peroxide; Hyperemia; In Vitro Techniques; KATP Channels; Mice; Mice, Inbred C57BL; Myocardial Contraction; Myocardium; NG-Nitroarginine Methyl Ester; Potassium Channel Blockers; Pyrimidines; Receptors, Purinergic P1; Theophylline; Triazoles | 2014 |
Translating drug-induced hibernation to therapeutic hypothermia.
Topics: Adenosine; Adenosine A1 Receptor Agonists; Animals; Body Temperature; CA1 Region, Hippocampal; Cell Death; Disease Models, Animal; Heart Arrest; Heart Rate; Hibernation; Hypothermia, Induced; Male; Neurons; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A1; Temperature; Theophylline | 2015 |
Effects of ATP and adenosine on contraction amplitude of rat soleus muscle at different temperatures.
Topics: Adenosine; Adenosine Triphosphate; Analysis of Variance; Animals; Carbachol; Cholinergic Agonists; Electric Stimulation; Hypothermia; Male; Muscle Contraction; Muscle, Skeletal; Nicotinic Antagonists; Purinergic P1 Receptor Antagonists; Purinergic P2 Receptor Antagonists; Rats; Rats, Wistar; Suramin; Temperature; Theophylline; Tubocurarine | 2017 |